Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesstrunk neural crest cell migration

LAMA5 NRP2

4.68e-056372GO:0036484
GeneOntologyBiologicalProcesstrunk segmentation

LAMA5 NRP2

4.68e-056372GO:0035290
GeneOntologyBiologicalProcessregulation of blood-brain barrier permeability

ZEB2 TJP3

1.40e-0410372GO:1905603
GeneOntologyBiologicalProcessneural crest cell migration

LAMA5 ZEB2 NRP2

1.87e-0462373GO:0001755
GeneOntologyBiologicalProcessmesenchymal cell migration

LAMA5 ZEB2 NRP2

2.05e-0464373GO:0090497
HumanPhenoBowed humerus

LAMA5 SPARC

4.52e-05872HP:0003865
DomainSPARC_Ca_bdg

SPARC SPOCK1

1.00e-048362PF10591
DomainSPARC/Testican_Ca-bd-dom

SPARC SPOCK1

1.00e-048362IPR019577
DomainFA58C

SSPOP NRP2

7.41e-0421362SM00231
DomainFA58C_3

SSPOP NRP2

7.41e-0421362PS50022
DomainFA58C_1

SSPOP NRP2

7.41e-0421362PS01285
DomainFA58C_2

SSPOP NRP2

7.41e-0421362PS01286
DomainGalactose-bd-like

LAMA5 SSPOP NRP2

7.82e-0494363IPR008979
DomainConA-like_dom

LAMA5 TRIM6 CELSR2 NRP2

8.07e-04219364IPR013320
DomainF5_F8_type_C

SSPOP NRP2

9.71e-0424362PF00754
DomainFA58C

SSPOP NRP2

9.71e-0424362IPR000421
DomainEGF_1

LAMA5 TENM4 CELSR2 SSPOP

1.42e-03255364PS00022
DomainEGF_LAM_2

LAMA5 CELSR2

1.52e-0330362PS50027
DomainEGF_LAM_1

LAMA5 CELSR2

1.52e-0330362PS01248
DomainEGF_2

LAMA5 TENM4 CELSR2 SSPOP

1.63e-03265364PS01186
DomainTNFR/NGFR_Cys_rich_reg

LAMA5 CELSR2

1.84e-0333362IPR001368
DomainLaminin_EGF

LAMA5 CELSR2

2.07e-0335362PF00053
DomainEGF_Lam

LAMA5 CELSR2

2.07e-0335362SM00180
DomainLAM_G_DOMAIN

LAMA5 CELSR2

2.43e-0338362PS50025
DomainLaminin_EGF

LAMA5 CELSR2

2.43e-0338362IPR002049
DomainLaminin_G_2

LAMA5 CELSR2

2.69e-0340362PF02210
DomainLamG

LAMA5 CELSR2

3.25e-0344362SM00282
DomainKAZAL

SPARC SPOCK1

3.54e-0346362SM00280
DomainKAZAL_2

SPARC SPOCK1

4.18e-0350362PS51465
DomainKazal_dom

SPARC SPOCK1

4.34e-0351362IPR002350
DomainLaminin_G

LAMA5 CELSR2

5.58e-0358362IPR001791
Domain-

SSPOP NRP2

8.71e-03733622.60.120.260
Pubmed

SPARC-null mice exhibit increased adiposity without significant differences in overall body weight.

SPARC SPOCK1

1.29e-06240212721366
Pubmed

Expression of SC1 is associated with the migration of myotomes along the dermomyotome during somitogenesis in early mouse embryos.

SPARC SPOCK1

3.87e-0634029732554
Pubmed

Asialoglycoprotein receptor genes are linked on chromosome 11 in the mouse.

SPARC ASGR2

7.73e-0644023234178
Pubmed

Pathogenic variants in MDFIC cause recessive central conducting lymphatic anomaly with lymphedema.

LAMA5 NRP2

1.93e-05640235235341
Pubmed

Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1.

KIRREL2 NRP2

3.60e-05840224797530
Pubmed

Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow.

LAMA5 NRP2

3.60e-05840232182215
Pubmed

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.

CELSR2 SSPOP

1.34e-041540220473291
Pubmed

Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation.

LAMA5 NRP2

1.73e-041740222306086
Pubmed

An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation.

TENM4 PBX3

1.95e-041840217350578
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

CELSR2 PBX3 ZEB2 NRP2

1.97e-0425140429031500
Pubmed

Gene expression in cortical interneuron precursors is prescient of their mature function.

PBX3 ZEB2

2.18e-041940218250082
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PHLDB3 LAMA5 KMT2B CELSR2 CANT1 USP40 TJP3

2.39e-04110540735748872
Pubmed

Multiple roles of lymphatic vessels in peripheral lymph node development.

LAMA5 NRP2

2.42e-042040230355615
Pubmed

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.

KMT2B UTY

2.42e-042040219047629
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

LAMA5 SSPOP ZEB2

2.44e-041054039628581
Pubmed

Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1.

ZEB2 NRP2

2.67e-042140223312517
Pubmed

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.

FADS1 CELSR2

4.12e-042640219060910
Pubmed

A global genomic transcriptional code associated with CNS-expressed genes.

SYPL2 HIPK3 ZEB2 NRP2

4.84e-0431840416919269
Pubmed

Goofy coordinates the acuity of olfactory signaling.

KIRREL2 NRP2

7.07e-043440223926254
Pubmed

Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development.

ZEB2 NRP2

8.83e-043840231597102
Pubmed

Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.

FADS1 PBX3 NRP2

9.27e-0416640319906978
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LAMA5 SPARC SSPOP

1.08e-0317540328071719
GeneFamilySPARC family

SPARC SPOCK1

6.91e-0582921278
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MSANTD2 MIDEAS

3.25e-0353292532
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TENM4 PBX3 ZEB2 STARD9 NRP2

6.52e-071854059f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TENM4 PBX3 ZEB2 STARD9 NRP2

6.87e-0718740513731298bc562ec29582f5da1b4c97261284f6f1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CATSPER3 SPARC KIRREL2 SPOCK1

1.07e-05153404c1335e7d7407412431ed4d8c7dfcb2c6086d8483
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PHLDB3 TENT4B PBX3 STARD9

1.69e-05172404a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PHLDB3 TENT4B PBX3 STARD9

1.81e-05175404f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TENM4 PBX3 ZEB2 NRP2

2.25e-051854041ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPARC PBX3 SPOCK1 NRP2

2.60e-0519240420ede290e01ad574afd122d72b59dbc52c595fad
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC KIRREL2 SPOCK1 NRP2

2.71e-051944041374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPARC PBX3 ZEB2 DKK2

2.88e-051974049af431323da6d099459b7360af40e5df998cffbd
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPARC TENM4 SPOCK1 DKK2

2.88e-051974042744cc94883c5d0424677cf5093bbab622933e9b
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Papillary_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

TENT4B UTY GNA13

2.51e-041374032a5d2a99a2c532480d00b80a4885514a8a5c80fa
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LAMA5 KIRREL2 SSPOP

2.85e-04143403d0ed8c25da1327085e042c2e03cb7503e2c52ce0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LAMA5 KIRREL2 SSPOP

2.85e-041434038900b92a24289204b9ec7baccc11594fec7694f1
ToppCell(08)_PNEC-(1)_24hpi|(08)_PNEC / shred by cell type and Timepoint

TENT4B SPOCK1

3.08e-0429402f1b59a0b6bce5772bfb084f08507cf775e7eae8c
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SPARC ZEB2

3.76e-0432402ba89b22a5ce8ee9f3099b1fa84721724b94c7759
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SPARC ZEB2

3.76e-043240258b212d4f2955f06a195df0f79ad95a8ff145b83
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA5 KIRREL2 DNLZ

3.82e-04158403e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA5 KIRREL2 DNLZ

3.82e-04158403d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CELSR2 MIDEAS ASGR2

3.89e-04159403ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CELSR2 MIDEAS ASGR2

3.89e-041594032f6c60ddff2208a68146f9786143d9aefd528840
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 SPARC NRP2

4.11e-041624032787be283b7a705647058aeb9bc54006ce5ffe95
ToppCellBAL-Mild-cDC_0|Mild / Compartment, Disease Groups and Clusters

CELSR2 MIDEAS ASGR2

4.18e-041634037047d3ba847930f42a6d5f71e18d49f3071c6409
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CATSPER3 SPOCK1 STARD9

4.25e-04164403f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC TTC22 DKK2

4.33e-04165403f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|356C / Donor, Lineage, Cell class and subclass (all cells)

PHLDB3 TENT4B STARD9

4.41e-04166403c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC KMT2B KIRREL2

4.49e-041674032184c2760b6142e62124a2454a552723e20d4f61
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 SPARC NRP2

4.72e-041704038d3c51364a332020810836e2055c60893c10d7f3
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDB3 ZEB2 NRP2

4.89e-04172403b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDB3 ZEB2 NRP2

4.89e-041724032f1673fcb2356684d60871debb0f159aec553a1c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC KIRREL2 SPOCK1

4.89e-041724036c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

LAMA5 MMP24 TRIM6

4.89e-041724030be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYPL2 DNLZ NRP2

5.06e-0417440316204ff504b7b382b4d90ca35003ad5336020e07
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPARC PBX3 NRP2

5.06e-041744039d22a554617a93701d0945de63cc3e7b24322c40
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LAMA5 SUN3 CELSR2

5.06e-041744032cd6638b361ca05ab83d09ce657194aed97873b7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC KIRREL2 SPOCK1

5.06e-04174403dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC SPOCK1 ZEB2

5.14e-041754031b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-HSC-MPP|lymph-node_spleen / Manually curated celltypes from each tissue

SUN3 SPARC IGLV10-54

5.23e-04176403de67ed15a50d2515ba6d152c1011a3367f77aedd
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 SPARC NRP2

5.31e-041774034a697866ed542d3201714234cee03451adf1dcc9
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Macrophage|bone_marrow / Manually curated celltypes from each tissue

SPARC TRIM6 NRP2

5.40e-0417840311a338032b59b936c5e65517c4160f7dd47a2cda
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

SPARC ZEB2 STARD9

5.49e-04179403342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCellThalamus-Macroglia|Thalamus / BrainAtlas - Mouse McCarroll V32

FADS1 SSPOP ZEB2

5.67e-041814034f62b63854a4e9fea6e839f0340e78392c66fb0e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC SPOCK1 ZEB2

5.67e-04181403a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

SPARC SPOCK1 DKK2

5.67e-04181403bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPARC TENM4 CELSR2

5.67e-041814033aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC SPOCK1 ZEB2

5.67e-04181403526e858a848470b6d2d5248788004d9735ed3add
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPARC TENM4 CELSR2

5.67e-04181403997ba1be2824b00d684f2163d0114656ed11fa53
ToppCell5'-Adult-Appendix-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPARC TENM4 CELSR2

5.67e-04181403e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PBX3 ZEB2 DKK2

5.76e-04182403205d9ad1ea4b7adee8054496cdde46c9c401a19a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC KIRREL2 SPOCK1

5.76e-04182403cde8fa4f42d25545abaa9ee885b4b1e24a5a8e08
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FADS1 TTC22 ZEB2

5.76e-04182403c6172aca2475bf0948a78e39f0dae6388504a915
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC TRIM6 NRP2

5.85e-04183403709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC TRIM6 NRP2

5.85e-04183403dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCellBasal|World / shred by cell class for mouse tongue

LAMA5 SPARC FADS1

5.85e-04183403c6729a207526ff4aa48176207b9353176f631fea
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_KLHL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHLDB3 SPARC DKK2

5.85e-04183403439b1d1373b7cc73d65f3b59037a6def7cf8f4ba
ToppCell10x5'-blood-Myeloid_Dendritic-DC1|blood / Manually curated celltypes from each tissue

TRIM6 PBX3 USP40

5.95e-0418440309fa465d1852b9b7e0405c27d4e5de276c9ba871
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZEB2 DKK2 NRP2

5.95e-04184403fea4fe648e9749177d0783443dc26a7df5807883
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZEB2 DKK2 NRP2

5.95e-0418440396a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPARC TENM4 SPOCK1

5.95e-041844034d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZEB2 DKK2 NRP2

5.95e-04184403780eb72da43527f0c72effac3423ec7384f05f20
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIDEAS UTY GNA13

6.04e-04185403eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC KIRREL2 SPOCK1

6.14e-041864031094c7140131454b2583200e1c01e81ccab3db23
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PBX3 ZEB2 NRP2

6.14e-041864037def03dd856b765bd3f493288641981c4f7fd26e
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TENM4 ZEB2 ASGR2

6.14e-0418640323b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPOCK1 ZEB2 STARD9

6.23e-0418740315d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPOCK1 ZEB2 STARD9

6.23e-04187403f62074b631fd45ad299c69d71b09267b04d656ee
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 DKK2 NRP2

6.23e-041874033912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

SPARC TENM4 SPOCK1

6.23e-04187403a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC ZEB2 STARD9

6.23e-04187403958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC ZEB2 STARD9

6.23e-0418740348bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZEB2 GNA13 NRP2

6.33e-041884033be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC KIRREL2 SPOCK1

6.33e-041884039db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC DKK2 NRP2

6.33e-04188403da862ea3c74f42d0dbae38b09211a45c593d477e
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC DKK2 NRP2

6.33e-04188403b82a7667ef74a05e8bc744f6c090a7cc7b8efe32
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPOCK1 ZEB2 STARD9

6.33e-0418840332f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC DKK2 NRP2

6.33e-0418840319672d284fe89c9c3c7697514ca1f659329c34f4
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SPARC ZEB2 NRP2

6.43e-041894039c2492c38f27e4c699b40680652e4c64911cce52
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

TENM4 ZEB2 NRP2

6.43e-0418940346c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC ZEB2 STARD9

6.43e-04189403fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC PBX3 SPOCK1

6.43e-04189403d00410010283dc6191ce9857d6c7952678fed588
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPARC PBX3 NRP2

6.43e-041894030a490730cdc912d5233de59057550de0e4065747
ToppCellfacs-Skin-nan-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZEB2 DKK2 NRP2

6.43e-0418940329287525120be2953b76881ba3cfc4379c265e7a
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

LAMA5 SPARC NRP2

6.43e-041894039a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCellfacs-Skin-nan-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZEB2 DKK2 NRP2

6.43e-041894037150dad9a92a715487c2d8130fa01b752ea69663
ToppCellfacs-Skin-nan-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZEB2 DKK2 NRP2

6.43e-041894036e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PBX3 ZEB2 NRP2

6.53e-041904037986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-3|TCGA-Ovary / Sample_Type by Project: Shred V9

SPARC ZEB2 NRP2

6.63e-0419140380d30d8eedb4c70b58440646325bc04c5700803e
ToppCellfacs-Thymus-Epithelium-3m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC TRIM6 NRP2

6.63e-04191403a157cee0fbc9dce64308128c3578e7327fa178b7
ToppCellfacs-Thymus-Epithelium-3m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC TRIM6 NRP2

6.63e-04191403d2311a5b0cf186839000f9f272b6fbc2270ddb44
ToppCellfacs-Thymus-Epithelium-3m-Endothelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC TRIM6 NRP2

6.63e-041914036676ef9aeb890668cb69e67865404061b8467c25
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-cDC2|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TENM4 ZEB2 ASGR2

6.73e-0419240390274b85f3d612b6a6d435860cd6d049ddeb1d96
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

SPARC TENM4 SPOCK1

6.73e-0419240360b1312e84f6d6448365a952469c506c00b5fe93
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SPARC TENM4 SPOCK1

6.73e-04192403d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPARC ZEB2 NRP2

6.73e-04192403de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPARC ZEB2 NRP2

6.73e-0419240325492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPARC PBX3 ZEB2

6.73e-04192403f053b89bfd6048c227667ff01c38df7c51d8a496
ToppCellControl-Myeloid-cMonocyte|Control / Disease state, Lineage and Cell class

TENT4B ZEB2 ASGR2

6.73e-04192403ad04c9c4bdebf94615cee1904ca48197e62c923b
ToppCellPBMC-Severe-cDC_0|Severe / Compartment, Disease Groups and Clusters

FADS1 CELSR2 ASGR2

6.73e-041924034f4774b925058191673b4ba4b4d05b8b37f61795
ToppCelldroplet-Bladder-nan-3m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC MIDEAS DKK2

6.83e-04193403e55f79bad6888b84b0ad5fccded498b170e3c6dc
ToppCell10x5'-blood|World / Manually curated celltypes from each tissue

SPARC BEND2 ASGR2

6.83e-04193403359d4242a7e5e51a3eaf6fe51bc1c653a402b054
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPARC PBX3 ZEB2

6.83e-04193403164cc8d51a67c2df3112338acbb1f93c5f838376
Diseaseasialoglycoprotein receptor 1 measurement

CELSR2 ASGR2

9.67e-064382EFO_0020164
Diseasedelta-5 desaturase measurement, response to polyunsaturated fatty acid supplementation

FADS1 HDGFL2

2.17e-0417382EFO_0007764, EFO_0009131
Diseasesodium-coupled monocarboxylate transporter 1 measurement

FADS1 CELSR2

2.72e-0419382EFO_0802076
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

FADS1 TTC22

5.15e-0426382OBA_2045191
Diseaseaortic stenosis

FADS1 CELSR2

7.33e-0431382EFO_0000266
Diseaseserum alanine aminotransferase measurement

LAMA5 MMP24 FADS1 TENM4 CELSR2 TJP3

7.91e-04869386EFO_0004735
Diseasebipolar I disorder

FADS1 TENM4 STARD9

7.97e-04141383EFO_0009963
DiseaseC-reactive protein measurement, high density lipoprotein cholesterol measurement

FADS1 CELSR2

8.83e-0434382EFO_0004458, EFO_0004612
Diseasefree cholesterol to total lipids in IDL percentage

FADS1 CELSR2

1.41e-0343382EFO_0022278
Diseaseapolipoprotein B measurement

SYPL2 FADS1 CELSR2 MIDEAS ASGR2

1.53e-03663385EFO_0004615
Diseasefree cholesterol to total lipids in small HDL percentage

FADS1 CELSR2

1.98e-0351382EFO_0022285
Diseasetotal cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement

FADS1 CELSR2

1.98e-0351382EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Diseaseomega-6 polyunsaturated fatty acid measurement

FADS1 CELSR2 ASGR2

2.08e-03197383EFO_0005680
Diseasefree cholesterol to total lipids in large HDL percentage

FADS1 CELSR2

2.38e-0356382EFO_0022279
Diseasefree cholesterol to total lipids in medium HDL percentage

FADS1 CELSR2

2.73e-0360382EFO_0022282
Diseasetriglycerides in medium LDL measurement

FADS1 CELSR2

2.91e-0362382EFO_0022322
Diseasefree cholesterol in very large HDL measurement

FADS1 CELSR2

2.91e-0362382EFO_0022273
Diseasecholesterol in very large VLDL measurement

FADS1 CELSR2

3.19e-0365382EFO_0022230
Diseaselow density lipoprotein cholesterol measurement, physical activity

FADS1 CELSR2

3.29e-0366382EFO_0003940, EFO_0004611
Diseasetotal lipids in very large HDL measurement

FADS1 CELSR2

3.29e-0366382EFO_0022312
Diseasetotal lipids in large VLDL

FADS1 CELSR2

3.39e-0367382EFO_0022175
Diseasefree cholesterol in large VLDL measurement

FADS1 CELSR2

3.49e-0368382EFO_0022265
Diseasecholesterol in very large HDL measurement

FADS1 CELSR2

3.59e-0369382EFO_0022229
Diseasetotal cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer

FADS1 CELSR2

3.59e-0369382EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
DiseaseManic Disorder

TENM4 STARD9

3.79e-0371382C0024713
DiseaseManic

TENM4 STARD9

4.56e-0378382C0338831
DiseaseDepression, Bipolar

TENM4 STARD9

4.67e-0379382C0005587

Protein segments in the cluster

PeptideGeneStartEntry
LHGNHWEDLGFQGAN

ELMOD3

191

Q96FG2
SPDNGDHDNWGNLAA

CATSPER3

201

Q86XQ3
VTQPDNWHGHELGGS

ASGR2

261

P07307
PGRANDGDWHHAQLA

CELSR2

1691

Q9HCU4
SNHDLGWQNLGRPHT

DKK2

156

Q9UBU2
QEDWGNHSQDLHGYP

MSANTD2

236

Q6P1R3
TGDEHSPGNWGHLDQ

CES1P1

181

Q9UKY3
TTNNNNNHHQPGAWA

TENT4B

26

Q8NDF8
LRQHLEGWGHNPENC

PHLDB3

511

Q6NSJ2
DEPWTLGNANHDGND

MMP24

261

Q9Y5R2
HNLNANGGWQDATTP

PBX3

401

P40426
QAGVQWHDHSSLQPQ

BEND2

86

Q8NDZ0
THNAHNWRLGQAPAN

CANT1

71

Q8WVQ1
LHGDDNGWTPNLDSN

NRP2

311

O60462
GQGQGQHEESWQDVP

KMT2B

326

Q9UMN6
LHIPWGDNSNQQHGD

GNA13

106

Q14344
AWSQEGPHRQHQGAE

LAMA5

3446

O15230
SQVQHFGSGHQEWNG

HIPK3

1056

Q9H422
GFNEGLWEIQNNPHA

HDGFL2

76

Q7Z4V5
PGCQNHHIIADNLGW

DNLZ

101

Q5SXM8
QAQAGWLQHDFGHLS

FADS1

171

O60427
QGAAWLQQHQGHPPK

IGLV10-54

51

A0A075B6I4
QPGQEATGNLFLHHW

MIDEAS

366

Q6PJG2
EQVAQWHDEQGHNGL

IPO9

726

Q96P70
WISGNAANGQHDLHI

KIRREL2

76

Q6UWL6
ETPWHGQGQGQDQDQ

SYPL2

236

Q5VXT5
NGSDNWNGGQSLSHH

UTY

396

O14607
WNGGQSLSHHPVQQV

UTY

401

O14607
GHSWAPGSQHQDACN

SSPOP

4126

A2VEC9
PREAWGFGHNHQALQ

STARD9

1776

Q9P2P6
PNHQEWDSGEHTNAC

ZNF572

106

Q7Z3I7
VHWQFGQLDQHPIDG

SPARC

231

P09486
NNHNWNTHGDPVEDP

SUN3

146

Q8TAQ9
AGPNHGNFLDNDQWL

SPOCK1

31

Q08629
LGWANGENQVEHSPH

TRAV7

16

A0A075B6U4
AGGAQEPAHAQENWL

TENM4

226

Q6N022
EGQHQGQWPPADTRH

nan

191

Q3C1V9
HQGAQVDSRHPQGQW

TJP3

866

O95049
GGVEHPWHNNEILQA

ZEB2

91

O60315
LQGPSGHWESHQDQT

USP40

941

Q9NVE5
EVAHEHPGNLNAWAN

TTC22

91

Q5TAA0
QPQSGYWVIGLQHNH

TRIM6

396

Q9C030