Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainSp1_fam

SP2 SP8 SP6 SP5 SP7

5.58e-09101415IPR030450
DomainAxin_b-cat-bd

AXIN1 AXIN2

5.66e-0521412IPR014936
DomainAxin_TNKS-bd

AXIN1 AXIN2

5.66e-0521412IPR032101
DomainAXIN1_TNKS_BD

AXIN1 AXIN2

5.66e-0521412PF16646
DomainAxin_b-cat_bind

AXIN1 AXIN2

5.66e-0521412PF08833
DomainDENND6

DENND6A DENND6B

5.66e-0521412IPR024224
DomainABL9/DENND6_dom

DENND6A DENND6B

3.36e-0441412IPR018307
DomainAvl9

DENND6A DENND6B

3.36e-0441412PF09794
DomainGPR1/GPR3/GPR5

ADGRG5 ADGRG3

3.36e-0441412IPR003910
Pubmed

Sp8 exhibits reciprocal induction with Fgf8 but has an opposing effect on anterior-posterior cortical area patterning.

SP8 SP6 SP5 SP7

3.69e-089146417509151
Pubmed

Mammalian SP/KLF transcription factors: bring in the family.

SP2 SP8 SP6 SP5 SP7

6.04e-0825146515820306
Pubmed

The gamma2 subunit of GABA(A) receptors is a substrate for palmitoylation by GODZ.

ZDHHC21 GABRG2 ZDHHC7

2.89e-074146315229235
Pubmed

Sp5 and Sp8 recruit β-catenin and Tcf1-Lef1 to select enhancers to activate Wnt target gene transcription.

AXIN2 SP8 SP5

4.00e-068146326969725
Pubmed

Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.

WNT10B AXIN2 SP8 SP5

1.11e-0533146418480165
Pubmed

Retinoid signaling is essential for patterning the endoderm of the third and fourth pharyngeal arches.

EPHA2 EPHA4

1.75e-052146210725232
Pubmed

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway.

AXIN1 AXIN2

1.75e-052146211809808
Pubmed

TR4 nuclear receptor suppresses HCC cell invasion via downregulating the EphA2 expression.

NR2C2 EPHA2

1.75e-052146229449527
Pubmed

Axin2 regulates chondrocyte maturation and axial skeletal development.

AXIN1 AXIN2

1.75e-052146219623616
Pubmed

Pharmacogenetic angiogenesis profiling for first-line chemotherapy in patients with advanced gastric cancer.

COL18A1 NOS3

1.75e-052146223641912
Pubmed

Evolving Models of Pavlovian Conditioning: Cerebellar Cortical Dynamics in Awake Behaving Mice.

GABRG2 SLC12A5

1.75e-052146226655909
Pubmed

Axin1 and Axin2 are regulated by TGF- and mediate cross-talk between TGF- and Wnt signaling pathways.

AXIN1 AXIN2

1.75e-052146218083923
Pubmed

Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer.

AXIN1 AXIN2

1.75e-052146215042511
Pubmed

Significant Associations between AXIN1 rs1805105, rs12921862, rs370681 Haplotypes and Variant Genotypes of AXIN2 rs2240308 with Risk of Congenital Heart Defects.

AXIN1 AXIN2

1.75e-052146233096676
Pubmed

Angiotensin AT1 receptor-associated protein Arap1 in the kidney vasculature is suppressed by angiotensin II.

NOS3 ARAP1

1.75e-052146222357923
Pubmed

A Novel Occulta-Type Spina Bifida Mediated by Murine Double Heterozygotes EphA2 and EphA4 Receptor Tyrosine Kinases.

EPHA2 EPHA4

1.75e-052146229312933
Pubmed

Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I.

INPP5A PLEK

1.75e-05214628999861
Pubmed

Eph-A2 and Eph-A4 expression in human benign and malignant thyroid lesions: an immunohistochemical study.

EPHA2 EPHA4

1.75e-052146221873938
Pubmed

Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation.

AXIN1 AXIN2

1.75e-052146228107521
Pubmed

Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors.

WNT10B WNT9A AXIN2 SP7

2.19e-0539146424586192
Pubmed

Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines.

AXIN1 AXIN2

5.24e-053146233811251
Pubmed

Differential expressions of the eph family of receptor tyrosine kinase genes (sek, elk, eck) in the developing nervous system of the mouse.

EPHA2 EPHA4

5.24e-05314627609620
Pubmed

Mouse axin and axin2/conductin proteins are functionally equivalent in vivo.

AXIN1 AXIN2

5.24e-053146215899843
Pubmed

Colorectal cancer and genetic alterations in the Wnt pathway.

AXIN1 AXIN2

5.24e-053146217143297
Pubmed

The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling.

AXIN1 AXIN2

5.24e-053146221383061
Pubmed

Coordinated action of Axin1 and Axin2 suppresses β-catenin to regulate muscle stem cell function.

AXIN1 AXIN2

5.24e-053146225866367
Pubmed

Insulin-like growth factor 1 receptor (IGF1R) signaling regulates osterix expression and cartilage matrix mineralization during endochondral ossification.

IGF1R SP7

5.24e-053146226475121
Pubmed

ADGB variants cause asthenozoospermia and male infertility.

ADGB CFAP69

5.24e-053146236995441
Pubmed

A cerebellar learning model of vestibulo-ocular reflex adaptation in wild-type and mutant mice.

GABRG2 SLC12A5

5.24e-053146224849355
Pubmed

A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases.

EPHA2 EPHA4

5.24e-053146216977320
Pubmed

ECK, a human EPH-related gene, maps to 1p36.1, a common region of alteration in human cancers.

EPHA2 EPHA4

5.24e-05314629119409
Pubmed

Mutations in components of the Wnt signaling pathway in gastric cancer.

AXIN1 AXIN2

5.24e-053146218330950
Pubmed

Interferon-inducible transmembrane proteins of the innate immune response act as membrane organizers by influencing clathrin and v-ATPase localization and function.

ATP6V0B IFITM1

5.24e-053146222467717
Pubmed

Prognostic Significance of High EphA1-4 Expression Levels in Locally Advanced Gastric Cancer.

EPHA2 EPHA4

5.24e-053146229491103
Pubmed

Role of Epiprofin, a zinc-finger transcription factor, in limb development.

AXIN2 SP8 SP6

6.68e-0519146319913006
Pubmed

Genome-wide transcriptional profiling reveals that HIV-1 Vpr differentially regulates interferon-stimulated genes in human monocyte-derived dendritic cells.

TNFSF9 IFITM1 OAS3 APOBEC3A

7.44e-0553146426116899
Pubmed

Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/β-catenin signaling.

AXIN2 PHEX SP7

9.12e-0521146334172578
Pubmed

Epithelial Wnt10a Is Essential for Tooth Root Furcation Morphogenesis.

WNT10B WNT9A AXIN2

9.12e-0521146331914354
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ATP13A1 JADE1 CAPN10 ZNF462 MEGF11

9.17e-05107146511347906
Pubmed

Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells.

DENND6A DENND6B

1.04e-044146222595670
Pubmed

Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation.

AXIN2 SP7

1.04e-044146225422448
Pubmed

A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes.

EPHA2 EPHA4

1.04e-044146210607706
Pubmed

Frameshift mutations of ATBF1, WNT9A, CYLD and PARK2 in gastric and colorectal carcinomas with high microsatellite instability.

CYLD WNT9A

1.04e-044146220854080
Pubmed

Mutations in WNT10B Are Identified in Individuals with Oligodontia.

WNT10B AXIN2

1.04e-044146227321946
Pubmed

Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer.

AXIN2 SP5

1.04e-044146224609463
Pubmed

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway.

AXIN1 AXIN2

1.04e-044146211336703
Pubmed

DENN domain proteins: regulators of Rab GTPases.

DENND6A DENND6B

1.04e-044146221330364
Pubmed

Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon.

AXIN1 AXIN2

1.04e-044146212072559
Pubmed

Blood flow controls bone vascular function and osteogenesis.

WNT10B NOS3 SP7

1.05e-0422146327922003
Pubmed

Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling.

WNT10B AXIN2 SP5

1.37e-0424146319165927
Pubmed

Mycn deficiency underlies the development of orofacial clefts in mice and humans.

WNT10B WNT9A SP7

1.37e-0424146334590686
Pubmed

Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

TM6SF2 ELFN2 RIPOR1 WDR90

1.46e-0463146411572484
Pubmed

Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.

IGF1R EPHA2 EPHA4

1.56e-0425146315254900
Pubmed

Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome.

EPHA2 EPHA4

1.74e-045146221935409
Pubmed

SP8 Transcriptional Regulation of Cyclin D1 During Mouse Early Corticogenesis.

AXIN2 SP8

1.74e-045146229599703
Pubmed

A 2.5-Mb transcript map of a tumor-suppressing subchromosomal transferable fragment from 11p15.5, and isolation and sequence analysis of three novel genes.

TSPAN32 PHLDA2

1.74e-04514629403053
Pubmed

Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway.

AXIN1 AXIN2

1.74e-045146211438668
Pubmed

A receptor protein tyrosine kinase implicated in the segmental patterning of the hindbrain and mesoderm.

EPHA2 EPHA4

1.74e-04514621295734
Pubmed

sFRP4-dependent Wnt signal modulation is critical for bone remodeling during postnatal development and age-related bone loss.

AXIN2 SP7

1.74e-045146227117872
Pubmed

Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.

DNAH7 DNAH6

1.74e-045146239056782
Pubmed

The SIAH E3 ubiquitin ligases promote Wnt/β-catenin signaling through mediating Wnt-induced Axin degradation.

AXIN1 AXIN2

1.74e-045146228546513
Pubmed

Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes. The Finnish Diabetes Prevention Study.

PCSK1 IGF1R

1.74e-045146215127203
Pubmed

Clinical significance of ephrin (eph)-A1, -A2, -a4, -a5 and -a7 receptors in pancreatic ductal adenocarcinoma.

EPHA2 EPHA4

1.74e-045146219949912
Pubmed

Phosphorylation of protein S by platelet kinases enhances its activated protein C cofactor activity.

CSNK2B PROC

1.74e-045146223580615
Pubmed

Conserved molecular interactions within the HBO1 acetyltransferase complexes regulate cell proliferation.

JADE1 ING4

1.74e-045146222144582
Pubmed

Eph receptors are involved in the activity-dependent synaptic wiring in the mouse cerebellar cortex.

EPHA2 EPHA4

1.74e-045146221559471
Pubmed

Embryonic stem cells express multiple Eph-subfamily receptor tyrosine kinases.

EPHA2 EPHA4

1.74e-04514628552593
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

TCEA1 SP2 ZNF536 ZDHHC7 TUT1 RNF187 ZNF462 ZRANB2 SP6 ING4 SP7

2.13e-047091461122988430
Pubmed

Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development.

WNT10B WNT9A AXIN2

2.20e-0428146324394376
Pubmed

The scaffolding protein JADE1 physically links the acetyltransferase subunit HBO1 with its histone H3-H4 substrate.

JADE1 ING4

2.60e-046146229382722
Pubmed

Regulation by afadin of cyclical activation and inactivation of Rap1, Rac1, and RhoA small G proteins at leading edges of moving NIH3T3 cells.

SIPA1 ARAP1

2.60e-046146219589776
Pubmed

EphA4 is not required for Purkinje cell compartmentation.

EPHA2 EPHA4

2.60e-046146211978390
Pubmed

Nkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cells.

SP2 SP5

2.60e-046146216201967
Pubmed

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.

AXIN1 AXIN2

2.60e-046146219759537
Pubmed

Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling.

AXIN1 AXIN2

2.60e-046146221799911
Pubmed

Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer.

AXIN1 AXIN2

2.60e-046146218708403
Pubmed

TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.

NR2C2 PDLIM7

2.60e-046146216446357
Pubmed

DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors.

ZDHHC21 ZDHHC7

2.60e-046146222031296
Pubmed

Cell-type-specific regulation of distinct sets of gene targets by Pax3 and Pax3/FKHR.

EPHA2 EPHA4

2.60e-046146215688035
Pubmed

Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract.

WNT10B WNT9A AXIN2

2.71e-0430146321936019
Pubmed

Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos.

AXIN2 SP8 SP5

2.71e-0430146331789450
Pubmed

Functional analysis of secreted and transmembrane proteins critical to mouse development.

ADAM23 EPHA2 EPHA4

2.99e-0431146311431694
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CYLD ZNF536 STRIP2 SLC12A5 SV2B RIPOR1 MCF2L MEGF11

3.40e-04407146812693553
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

ADGRG5 ADGRG3 GPR20 GPR148

3.51e-0479146412679517
Pubmed

Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development.

WNT10B AXIN2 SP5

3.61e-0433146327414999
Pubmed

PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells.

NOS3 PROC

3.63e-047146226457757
Pubmed

RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling.

AXIN1 AXIN2

3.63e-047146221478859
Pubmed

Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21.

WNT10B WNT9A

3.63e-04714629441749
Pubmed

Reciprocal interaction between mesenchymal stem cells and transit amplifying cells regulates tissue homeostasis.

AXIN2 IGF1R

3.63e-047146233480845
Pubmed

Modeled changes of cerebellar activity in mutant mice are predictive of their learning impairments.

GABRG2 SLC12A5

3.63e-047146227805050
Pubmed

A new gain-of-function mouse line to study the role of Wnt3a in development and disease.

AXIN2 SP5

3.63e-047146227411055
Pubmed

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin.

AXIN1 AXIN2

3.63e-047146210698523
Pubmed

TGIF governs a feed-forward network that empowers Wnt signaling to drive mammary tumorigenesis.

AXIN1 AXIN2

3.63e-047146225873176
Pubmed

Several receptor tyrosine kinase genes of the Eph family are segmentally expressed in the developing hindbrain.

EPHA2 EPHA4

3.63e-04714627947319
Pubmed

Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy.

CYLD ADGB

3.63e-047146222019778
Pubmed

Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling.

WNT10B AXIN1 AXIN2

3.94e-0434146323293290
Pubmed

GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis.

WNT9A NKX3-2 AXIN2

4.30e-0435146331167144
Pubmed

Ovarian development in mice requires the GATA4-FOG2 transcription complex.

WNT9A AXIN2 SP5

4.67e-0436146318927154
Pubmed

Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals.

WNT9A NKX3-2 AXIN2

4.67e-0436146331604927
Pubmed

Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.

ADGRG5 ADGRG3

4.82e-048146212435584
GeneFamilyZinc fingers C2H2-type|Sp transcription factors

SP2 SP8 SP6 SP5 SP7

4.96e-109975755
GeneFamilyAdhesion G protein-coupled receptors, subfamily G

ADGRG5 ADGRG3

5.88e-047972917
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

SP2 ZNF536 ZNF678 REPIN1 ZNF462 SP8 ZNF837 SP6 SP5 ZBTB11 SP7

1.60e-03718971128
GeneFamilyFibronectin type III domain containing

ELFN2 IGF1R EPHA2 FNDC9 EPHA4

1.71e-03160975555
GeneFamilyFibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors

EPHA2 EPHA4

2.49e-03149721095
GeneFamilyC2 domain containing|Calpains

CAPN10 ADGB

2.86e-0315972975
GeneFamilyDyneins, axonemal

DNAH7 DNAH6

3.68e-0317972536
GeneFamilyWnt family|Endogenous ligands

WNT10B WNT9A

4.59e-0319972360
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBGABA

GABRG2 TMC7 ADAM23 SCAMP1 BRINP1 ELFN2 SLC12A5 PTPN5 ZNF462 BLCAP FBXL16 NALF1 SV2B SCN3A MCF2L

8.03e-0670314415M39070
CoexpressionAtlasBM Top 100 - accumbens

GABRG2 STRIP2 SLC12A5 PTPN5 FBXL16 KCNQ5

1.18e-05781386BM Top 100 - accumbens
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK1 GABRG2 ADAM23 NDFIP2 BRINP1 NALF1 KCNQ5 SV2B EPHA4

1.74e-0819514692e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellMesenchymal_cells-Stromal_fibro.|Mesenchymal_cells / Lineage and Cell class

TMC7 TNFSF9 COL28A1 ECM1 SLC12A5 COL18A1 TLR5 GPRC5B

1.54e-071811468f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PCSK1 GABRG2 XKR7 FBXL16 SV2B SCN3A ELAPOR1 PROC

1.98e-07187146898477ba04a42a8da80a72f41a182429f46283595
ToppCellCOVID-19-Heart-EC_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

PTPN5 APOLD1 SV2B MCF2L NOS3 TBCD GPRC5B EPHA4

2.15e-071891468fe49852ba15f948b384d6b4c258927c70b741357
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL28A1 DNAH7 ADGB CFAP54 WDR90 CFAP69 DNAH6 CFAP46

2.62e-0719414684a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 GABRG2 SLC12A5 PTPN5 KCNQ5 SCN3A ELAPOR1 FNDC9

2.73e-071951468ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH7 LRRC9 ADGB CFAP54 WDR90 CFAP69 DNAH6 CFAP46

2.95e-07197146874a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-4|TCGA-Cervix / Sample_Type by Project: Shred V9

DNAH7 XKR7 CFAP54 CFAP69 DNAH6 MEGF11 CFAP46

4.52e-071421467369f2e51e0283a4de70e6c7a3b95672c0838f205
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MPV17L PKD2L1 ELFN2 FAM221B SP8 NALF1 TLR5

4.97e-071441467e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 ELFN2 APOLD1 SCN3A DNAH6 NOS3 SFT2D1

6.55e-07150146796b160f163030fbf48aedc37d6ae224e11492c52
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH7 LRRC9 ADGB CFAP54 CFAP69 DNAH6 CFAP46

1.46e-061691467fba841664939c771881ba97f14ef1df6635c04ff
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PCSK1 ADGRG3 SLC12A5 XKR7 SV2B SCN3A PROC

1.84e-0617514679941c35601134d88d1b3249c81f8b43a8fc61610
ToppCellE18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG3 REPIN1 ELFN2 COL18A1 APOLD1 SCN3A RIPOR1

1.98e-0617714678dfadd9852e0c256363471a7cfe6af120c8c51e0
ToppCellE18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG3 REPIN1 ELFN2 COL18A1 APOLD1 SCN3A RIPOR1

1.98e-061771467767b2af5f224d100b22bed32f86cec1cd17e8711
ToppCellE18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG3 REPIN1 ELFN2 COL18A1 APOLD1 SCN3A RIPOR1

1.98e-0617714675ef2527e9b41e62f1724cdabaad9d8979266bb7d
ToppCellE18.5-Endothelial-Endothelial_lymphatic|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG3 REPIN1 ELFN2 COL18A1 APOLD1 SCN3A RIPOR1

1.98e-061771467ae1d2fdd4f67f50c906b27ea084de058c6908aa2
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

PTPN5 NALF1 SV2B MCF2L NOS3 TBCD EPHA4

2.47e-061831467ff95382cfed592190d0636d2b750328471f82e0d
ToppCelldroplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 WNT9A COL18A1 TRAM1L1 APOLD1 TSPAN4 NOS3

2.85e-0618714679c9ae8725905ba0cfe407878006ed06c2480fb72
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 WNT9A COL18A1 TRAM1L1 APOLD1 TSPAN4 NOS3

2.85e-0618714679e9460e57cdc9cd0a0de2866b140e06d0bc19a8f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAM23 NDFIP2 BRINP1 KCNQ5 SV2B DNAH6 EPHA4

3.06e-061891467a75226616340045b581d08429d2e123e041dee55
ToppCell(01)_Cycling_Basal_(homeostasis)-(4)_1wkpi|(01)_Cycling_Basal_(homeostasis) / shred by cell type and Timepoint

TNFSF9 TM6SF2 ELFN2 SP8 SP6 MCF2L

3.12e-061221466b2a070939c0660c82a1130ef423fd627e9e087ab
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRIP2 SLC12A5 PTPN5 FBXL16 KCNQ5 SCN3A FNDC9

3.17e-0619014671c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PCSK1 GABRG2 PKD2L1 XKR7 SV2B SCN3A ELAPOR1

3.17e-0619014672375e604eacd38f61f3e661ba2f76d286fcceca7
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAM23 NDFIP2 BRINP1 KCNQ5 SV2B DNAH6 EPHA4

3.17e-06190146749e09cdb843b3d889a06a811aa5affae68b25a75
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PCSK1 GABRG2 FBXL16 SV2B SCN3A ELAPOR1 PROC

3.17e-061901467b1095b2a7467c152d16e4f19a9515aeb61fc9e3d
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PCSK1 SLC12A5 XKR7 FBXL16 SV2B ELAPOR1 PROC

3.17e-061901467b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCellLAM-Endothelial-LymEndo|LAM / Condition, Lineage and Cell class

ADGRG3 COL18A1 APOLD1 SV2B SCN3A NOS3 GPRC5B

3.51e-06193146768eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PCSK1 GABRG2 PKD2L1 XKR7 SV2B SCN3A ELAPOR1

3.51e-0619314678603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 GPR20 INPP5A IFITM1 ADRA1D APOLD1 SCN3A

3.64e-061941467b8a130ffae68ffe550bf335460a1ec1035cf8d8d
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MPV17L DNAH7 ADGB WDR90 CFAP69 DNAH6 CFAP46

3.76e-06195146779dc031258579ea328181dda33710dd897f1064a
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PCSK1 GABRG2 SLC12A5 SV2B SCN3A ELAPOR1 PROC

3.76e-0619514675f33ece997f074598b4201ff74f592ee07c86a06
ToppCellcontrol-Myeloid-Neutrophils_2|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ADGRG3 PDLIM7 IFITM1 OAS3 APOBEC3A DDX60L PLEK

4.02e-0619714678819db1550bf14566c6d33d97f7f83419e867ace
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 ADAM23 BRINP1 SLC12A5 NALF1 KCNQ5 EPHA4

4.16e-0619814678ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNAH7 LRRC9 ADGB CFAP54 PIK3C2G SV2B DNAH6

4.44e-06200146796701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

DNAH7 ADGB CFAP54 WDR90 CFAP69 DNAH6 CFAP46

4.44e-0620014676a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ECM1 DNAH7 LRRC9 ADGB CFAP54 ELAPOR1 DNAH6

4.44e-062001467da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ECM1 DNAH7 LRRC9 ADGB CFAP54 ELAPOR1 DNAH6

4.44e-06200146772c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_smooth_muscle-like|E16.5-samps / Age Group, Lineage, Cell class and subclass

ZNF536 TM6SF2 FAM221B LRRC9 PHEX CFAP69

4.93e-0613214669633653dba1edee47d915212fb6e68426da49de5
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH7 LRRC9 ADGB CFAP54 DNAH6 CFAP46

9.50e-061481466d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH7 LRRC9 ADGB CFAP54 DNAH6 CFAP46

9.50e-061481466c8e93b87212f55774223caa385859c566fa1981f
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

DNAH7 ADGB CFAP54 ELAPOR1 DNAH6 CFAP46

1.07e-0515114668216462e723fec2797387929dde095370947e10a
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH7 LRRC9 ADGB CFAP54 DNAH6 CFAP46

1.19e-0515414664e3bc24043144143842627cacf6f90dda2228910
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH7 LRRC9 ADGB CFAP54 DNAH6 CFAP46

1.19e-0515414669ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH7 LRRC9 ADGB CFAP54 DNAH6 CFAP46

1.19e-0515414667556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH7 LRRC9 ADGB CFAP54 DNAH6 CFAP46

1.19e-05154146658072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH7 LRRC9 ADGB CFAP54 DNAH6 CFAP46

1.24e-0515514665f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH7 LRRC9 ADGB CFAP54 DNAH6 CFAP46

1.24e-0515514660944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH7 CFAP54 WDR90 CFAP69 DNAH6 CFAP46

1.33e-051571466410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

ATP13A1 ELFN2 STRIP2 EPHA2 SCART1 WDR90

1.43e-051591466655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellE16.5-Endothelial-Endothelial_lymphatic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG3 TMC7 SIPA1 APOLD1 SCN3A RIPOR1

1.89e-051671466b93103a868fba63a8910bffb690a6242b9252833
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG3 TMC7 SIPA1 APOLD1 SCN3A RIPOR1

1.89e-051671466fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG3 TMC7 SIPA1 APOLD1 SCN3A RIPOR1

1.89e-051671466f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG3 TMC7 SIPA1 APOLD1 SCN3A RIPOR1

1.89e-05167146626cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

2.02e-05169146614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 IFITM1 TSPAN32 PHLDA2 MFAP4 PLEK

2.23e-0517214663ffe721f62c0d20c1d765ecb15ed4e1aa88099f7
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 IFITM1 TSPAN32 PHLDA2 MFAP4 PLEK

2.23e-0517214662bbe3f601a56577d200aa7ba7031f7c19b988cc1
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 TNFSF9 IFITM1 ECM1 AXIN2 WDR90

2.30e-051731466a5b6c3d58f7a8e533330798b81496009a31548af
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 IFITM1 TSPAN32 PHLDA2 MFAP4 PLEK

2.30e-0517314667c5e4809205ce1a0a301c15442af00a2e2b9b301
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 TNFSF9 IFITM1 ECM1 AXIN2 WDR90

2.30e-051731466cc094992b8027f4cef38f0fb0b76f0d07210d1e2
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRG3 MPV17L TSPAN32 JMY KCNQ5 SCART1

2.38e-051741466c0204a0d0a979a489e8d30dc5396e99da14c119c
ToppCellThalamus-Neuronal-Excitatory|Thalamus / BrainAtlas - Mouse McCarroll V32

NR2C2 WNT9A RNF187 FBXL16 SV2B ELAPOR1

2.54e-051761466d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Neutrophil|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRG3 TSPAN32 AXIN2 ADRA1D ELAPOR1 S1PR4

2.54e-051761466676839d07450b313222622e0ffd305c732cbad6d
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRG3 COL18A1 APOLD1 DNAH6 NOS3 SP7

2.54e-051761466460cb302c5b3d609c65b924e1d4e8ea057a68485
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ZNF536 DNAH7 ADGB CFAP54 DNAH6 CFAP46

2.62e-051771466c38138fb5ad9766c2d240811210c854338cd612e
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

2.79e-0517914665e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-3|TCGA-Endometrium / Sample_Type by Project: Shred V9

ADGRG5 TNFSF9 ZDHHC7 PHLDA2 ELFN2 S1PR4

2.79e-051791466f36776299e570345e18dc38cdef4cfc90e7ed7c2
ToppCellwk_20-22-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PCSK1 GABRG2 XKR7 FBXL16 ELAPOR1 PROC

2.79e-05179146606f92c884189197c86793191c05f65e34925c097
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MPV17L DNAH7 WDR90 CFAP69 DNAH6 CFAP46

2.88e-0518014661f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH7 ADGB CFAP54 DENND6B WDR90 CFAP46

2.88e-05180146692fb01b91261b3103454924cde56add337b41844
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

DNAH7 ADGB CFAP54 DENND6B DNAH6 CFAP46

3.06e-0518214667ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-pDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ELFN2 FAM221B PHEX EPHA2 PLEK PROC

3.06e-05182146602c0824373a0ecebc922d4ca848ace9d570722c4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DNAH7 KCNQ5 SV2B DNAH6 CFAP46 EPHA4

3.06e-05182146614a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

DNAH7 LRRC9 ADGB CFAP54 DNAH6 CFAP46

3.06e-051821466e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCellwk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PCSK1 GABRG2 SLC12A5 SV2B ELAPOR1 PROC

3.16e-0518314668820cfed27b292bc0bc9cde4005219ed41900552
ToppCellMesenchymal_cells-Osteoblasts|Mesenchymal_cells / Lineage and Cell class

MPV17L FAM221B PHEX EPHA2 SCN3A SP7

3.16e-051831466d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCell10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ADGRG3 OXER1 IRF2BP1 DGKQ MCF2L ZBTB11

3.16e-051831466f9a3af96c0fb7d5c4d7df6db8b2c42e322418c08
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

3.25e-0518414665daff849625f2f41d56615569c0ed59cd733b34c
ToppCellCiliated_cells-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

3.35e-0518514664fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

3.35e-0518514665e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

3.35e-051851466f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell18-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

PCSK1 PKD2L1 FBXL16 SV2B SCN3A ELAPOR1

3.35e-051851466f8fc7b12b4e18d23d84e95488be93c4352d325f3
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

3.46e-05186146676033438426d8f9c72cd6691a7baf92104c9f03d
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 ADAM23 INPP5A IGF1R APOLD1 NOS3

3.46e-0518614662cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 ADAM23 INPP5A IGF1R APOLD1 NOS3

3.46e-05186146690d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

3.46e-05186146685787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

3.56e-051871466f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellE12.5-Endothelial|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRG3 SIPA1 COL18A1 APOLD1 NOS3 S1PR4

3.56e-051871466b8ed57b3c39ffbf750cd08a3e03ec11dae43d00e
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 GPR20 IFITM1 ADRA1D APOLD1 SCN3A

3.56e-051871466accb8a78b885703a27d4b560f0053f03d82ff3af
ToppCell3'_v3-blood-Myeloid_Dendritic-DC1|blood / Manually curated celltypes from each tissue

TNFSF9 PHLDA2 ADGB EPHA2 PLEK PROC

3.67e-051881466411d4dd5c9dee7ebd8db352640cf009e7b033ba9
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRG3 WNT9A COL18A1 APOLD1 NOS3 GPRC5B

3.67e-051881466dc52dd2957be3f40001f0a56f3d9ac9d66ea466e
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

3.67e-05188146634b11f72ca73153d02edcd09b38983ad1a504659
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRG3 WNT9A COL18A1 APOLD1 NOS3 GPRC5B

3.67e-0518814662ef08313087e91985bcffc46c3798470cdeec49c
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRG3 WNT9A COL18A1 APOLD1 NOS3 GPRC5B

3.67e-0518814661f1604b6dc0a8ad0be3d9aac0bef448459c22465
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

3.67e-0518814662b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCelldroplet-Limb_Muscle-nan-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 ADGRG3 APOLD1 RIPOR1 MCF2L NOS3

3.78e-051891466a3f6ebd1622d36d114e42f6e0618d7b2fe8b9a2f
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

3.78e-05189146668a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCelldroplet-Limb_Muscle-nan-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER2 ADGRG3 APOLD1 RIPOR1 MCF2L NOS3

3.78e-051891466d86455cf20769d70d62e2c1dd92cbc93c67aada5
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRIP2 PTPN5 FBXL16 KCNQ5 SCN3A FNDC9

3.78e-0518914663e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRIP2 PTPN5 FBXL16 KCNQ5 SCN3A FNDC9

3.78e-051891466851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

DNAH7 ADGB CFAP54 CFAP69 DNAH6 CFAP46

3.78e-051891466b679920f0993e917dd86da082113bfbd85ea1ca5
Drug2-propylpentanoic acid; Down 200; 50uM; PC3; HT_HG-U133A

IRF2BP1 ADAM23 PDLIM7 NKX3-2 IFITM1 DNAH7 ADRA1D ING4 EPHA4

4.52e-0619614494446_DN
DrugQuinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; PC3; HT_HG-U133A

CYLD TUT1 ECM1 AXIN1 PHEX IGF1R RIPOR1 MCF2L TBCD

4.91e-0619814495793_DN
Diseasemetachronous colorectal adenoma

ZNF536 TSPAN32 SLC6A11 NALF1

5.40e-05451354EFO_0803377
Diseasecardiovascular disease

INPP5A PKD2L1 AXIN1 ADRA1D APOLD1 EPHA2 SP6 MCF2L NOS3

2.65e-044571359EFO_0000319
DiseaseFebrile Convulsions

GABRG2 SLC12A5

7.32e-0491352C0009952
Diseaselevel of Sterol ester (27:1/16:1) in blood serum

PKD2L1 TM6SF2

7.32e-0491352OBA_2045190
DiseaseOligodontia

WNT10B AXIN2

1.33e-03121352C4082304
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

GABRG2 SCN3A

1.33e-03121352DOID:0060170 (implicated_via_orthology)
Diseasecerebral white matter volume change measurement

ADRA1D SCART1

1.33e-03121352EFO_0021499
Diseasesleep duration, triglyceride measurement

INPP5A MPV17L TM6SF2 SLC30A10

1.35e-031041354EFO_0004530, EFO_0005271
Diseasemyopathy (implicated_via_orthology)

PDLIM7 COL18A1 MEGF11

1.39e-03481353DOID:423 (implicated_via_orthology)
Diseasecardiomyopathy (biomarker_via_orthology)

IGF1R NOS3

1.57e-03131352DOID:0050700 (biomarker_via_orthology)
DiseaseRespiratory Depression

IGF1R TBCD

1.57e-03131352C0235063
DiseaseRespiratory Insufficiency

IGF1R TBCD

1.57e-03131352C0035229
DiseaseRespiratory Failure

IGF1R TBCD

1.57e-03131352C1145670
Diseasefrontotemporal dementia, age at onset

BANF2 COL28A1

1.57e-03131352EFO_0004847, MONDO_0017276
DiseaseHypodontia

WNT10B AXIN2

1.82e-03141352C0020608
Diseaselifestyle measurement, alcohol consumption measurement

BRINP1 TSPAN32 ADRA1D CFAP54

1.96e-031151354EFO_0007878, EFO_0010724
Diseasecolorectal health

ST7 ADRA1D NALF1 MDFIC2 EPHA4

2.37e-032011355EFO_0008460
Diseaseomega-3 polyunsaturated fatty acid measurement, diet measurement

ADRA1D EPHA2

2.39e-03161352EFO_0008111, EFO_0010119
Diseaseliver fat measurement, liver disease biomarker

TM6SF2 SLC30A10

2.39e-03161352EFO_0006845, EFO_0010821
Diseaselow density lipoprotein particle size measurement

BANF2 PKD2L1 SP6

2.40e-03581353EFO_0008593
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

DGKQ TM6SF2 JMY BUD23 SP6

2.63e-032061355EFO_0004612, EFO_0020947
Diseasebody fat percentage, type 2 diabetes mellitus

SP6 ARAP1

2.70e-03171352EFO_0007800, MONDO_0005148
Diseasebody surface area

PCSK1 ZNF678 KCNG3 AXIN1 AXIN2 ZNF462 IGF1R GPRC5B EPHA4

2.88e-036431359EFO_0022196
DiseaseCongenital hernia of foramen of Morgagni

IGF1R KCNQ5

3.38e-03191352C0265699
DiseaseCongenital hernia of foramen of Bochdalek

IGF1R KCNQ5

3.38e-03191352C0265700
Diseaseacetone measurement

SCART1 SFT2D1

3.38e-03191352EFO_0010989
DiseaseFetal Growth Retardation

IGF1R NOS3

3.74e-03201352C0015934
DiseaseBenign Neoplasm

APOBEC3A EPHA2 NOS3

3.78e-03681353C0086692
DiseaseNeoplasms

APOBEC3A EPHA2 NOS3

3.78e-03681353C0027651
DiseaseCongenital diaphragmatic hernia

IGF1R KCNQ5

4.12e-03211352C0235833
Diseasegastric ulcer (biomarker_via_orthology)

COL18A1 NOS3

4.12e-03211352DOID:10808 (biomarker_via_orthology)
DiseaseAgents acting on the renin-angiotensin system use measurement

WNT9A SIPA1 ADRA1D APOLD1 SP6 NOS3

4.52e-033351356EFO_0009931

Protein segments in the cluster

PeptideGeneStartEntry
WRHTQFAVERCGFCG

CEP295NL

11

Q96MC4
FDGCISISAVQWLCN

BUD23

116

O43709
CRCFGAWQQFVQRGS

C1orf167

686

Q5SNV9
AAFKCWCQALDDIFR

CFAP54

1936

Q96N23
RWIQCSKHDVFCGFL

ADAM23

646

O75077
LFNACVSGSWDCVNL

ASB9

106

Q96DX5
WDCIATCFFIDTAHN

CARNMT1

306

Q8N4J0
GFWGTFLESQRSCVC

BRINP1

401

O60477
TLALFCWISDRAFCE

ACER2

186

Q5QJU3
IWLDFEDFCVCFQNI

ADGB

631

Q8N7X0
WQGQGRAAAFLCCSF

C9orf163

11

Q8N9P6
CFSWGCAGEVRAFLQ

APOBEC3A

101

P31941
FFVFQVFCVGLWCLD

ATP13A1

246

Q9HD20
CARAVCAFVWLAAGA

GPR20

166

Q99678
LEFCGETWSSLCTFF

FGFBP1

211

Q14512
QGVWDVCRTASRFCL

CFAP46

591

Q8IYW2
LCSDFIWGLAGFLCD

DGKQ

76

P52824
FALFNSLQGVFICCW

ADGRG3

506

Q86Y34
REKCVDTLDFWFACN

AXIN2

101

Q9Y2T1
CFSRCQREDVFWLPL

CAPN10

136

Q9HC96
SCFFWVVLFSAGCKV

CD180

6

Q99467
ARFSAWLECVCVVTF

DENND6B

36

Q8NEG7
RVGFAAFSVLWACCS

ANXA2R

171

Q3ZCQ2
AFSVLWACCSRICGA

ANXA2R

176

Q3ZCQ2
ACWNELFTLGLAQCA

NR2C2

421

P49116
CFAAQLGFELISWLC

RIC1

1081

Q4ADV7
ALRNFFYSCAGWCVV

PIK3C2G

1011

O75747
FAASQFLLACGVLWF

PTPN5

91

P54829
AICIGWFTAECIVRF

KCNG3

226

Q8TAE7
LCIGAAAFSQCEEWS

KCNK9

171

Q9NPC2
NFCYELILSRFCAWD

LRRC9

406

Q6ZRR7
FFCRWQGCGDRQLLQ

APOLD1

171

Q96LR9
WVRGSLVLFGSCTFC

OTOP3

161

Q7RTS5
WTGLFCTQRCPAAFF

MEGF11

731

A6BM72
ECSWAGLFSFQDLRA

JMY

226

Q8N9B5
EWANCFTLCCRAVGF

NGLY1

311

Q96IV0
AVLAFICLQFWCVRC

FNDC9

126

Q8TBE3
FGLEFIIRIWSAGCC

KCNQ5

171

Q9NR82
CDGCNFHFLWESAAA

ELAPOR1

841

Q6UXG2
CEYFILSNLNVFGCW

DDX60L

336

Q5H9U9
WEGATSCTCDRGFFR

EPHA4

301

P54764
FEGWRCVDRDFCANI

IGF1R

271

P08069
FIRTRWCIADCAFDL

INPP5A

166

Q14642
RVCLFLSSGCWFLGS

OR2T4

171

Q8NH00
FCEALQDACWSRLGG

COL18A1

411

P39060
CFESNFLCAACDRRW

FAM221B

356

A6H8Z2
CDAGWTMFCQNVRFL

LRRC31

466

Q6UY01
WKCNCSFLDFAIFLI

LRRC52

186

Q8N7C0
CDFLFSGANSVWCET

MRGPRX3

161

Q96LB0
WGAIAACTVFARCLI

OXA1L

141

Q15070
ALGFSWHDTCFVCAI

PDLIM7

416

Q9NR12
ETWRFGAAACKVNLF

OXER1

156

Q8TDS5
RGWAQAAFQAACETF

NOS3

696

P29474
RFLWGVLFALCFSCL

GPRC5B

126

Q9NZH0
WEGRFCQREVSFLNC

PROC

126

P04070
FIFNWLGFCLSFCIT

NDFIP2

241

Q9NV92
ASVAAAPAVCCWRLF

NKX3-2

41

P78367
AVCFRVALACWVGGL

OR6S1

141

Q8NH40
QSGAWCCFDEFNRID

DNAH6

1516

Q9C0G6
LAALFLICYSCWGNC

BLCAP

51

P62952
DKQVNSCARFWFSGC

COL28A1

1091

Q2UY09
NEAEFQRWLICCFGA

BANF2

56

Q9H503
WFCCVFGDSLLETVS

CENPL

161

Q8N0S6
ARACFALLWGCALAA

EPHA2

6

P29317
CADLLDFWFACTGFR

AXIN1

111

O15169
CTALIANCFWRIYAE

GPR148

231

Q8TDV2
LSCGAWACFDEFNRI

DNAH7

1371

Q8WXX0
SFFCCFEDCRTGAWR

GABRG2

416

P18507
WCFLARYGTAELCAH

C1orf112

461

Q9NSG2
DSFSAWLHCVCVVGF

DENND6A

56

Q8IWF6
SWFCGLRGNEFFCEV

CSNK2B

11

P67870
SLWRQCSDCPFFQEC

MCF2L

736

O15068
HWCCTRQGEARFSCF

ECM1

256

Q16610
WDGRFDGVQLCSFAC

CYLD

276

Q9NQC7
CQGNARVLAFLEWCE

CFAP69

441

A5D8W1
LLGWNCLCAFDRCSS

S1PR4

181

O95977
WGLGVLLFCAATACF

SBK3

226

P0C264
LLFCAATACFPWDVA

SBK3

231

P0C264
FGVCFLSCLDVWNLK

FPGT

506

O14772
WDFSEAVCRGCVNFE

IRF2BP1

26

Q8IU81
DCSIEWFHFACVGLT

ING4

216

Q9UNL4
CASLILACLFCQFWD

MDFIC2

106

A0A1B0GVS7
AFGLQCCLLFLLASW

MUCL3

11

Q3MIW9
WGLFCSSRFLNATCD

SLC12A5

341

Q9H2X9
TIFAWEQGCRQDCFN

OAS3

636

Q9Y6K5
LFNTLFLNWCCLGFI

IFITM1

41

P13164
CRLLVGALWAFSCFI

OR1M1

141

Q8NGA1
SLYLRWCCQVQDFGL

FBXL16

401

Q8N461
RGWACFCALLNVLSI

SLC35G5

101

Q96KT7
VESCWFFGDFLCRLH

TAAR5

96

O14804
FVCNWLFCGKSFTRS

SP5

326

Q6BEB4
GDNSQFCWRNLFSCI

STRIP2

651

Q9ULQ0
QCLFCGTSIAAWNAL

SV2B

596

Q7L1I2
FCRACVVRFWAEEDG

RNF187

31

Q5TA31
IFNHCFTGNCVIDWL

PLEK

151

P08567
VQNCAALSSGAFWFR

MFAP4

196

P55083
DCNCFRSIDLGWSGF

MEP1A

556

Q16819
GRVVFNCACRDVLAW

SIPA1

626

Q96FS4
VTLFLNIFGCLAWFC

SCAMP1

161

O15126
NIFGCLAWFCVDSAR

SCAMP1

166

O15126
LAWFCVDSARAVDFG

SCAMP1

171

O15126
TTFVVCNECGNRWKF

TCEA1

286

P23193
YRFANVFLIWDCCDA

SCN3A

731

Q9NY46
CNWLFCGKRFTRSDE

SP6

286

Q3SY56
WALVCSLCNEKFGAS

JADE1

311

Q6IE81
FCSAEFRDWNCKSIF

ST7

551

Q9NRC1
AWTFIGCLLRLSFCG

OR5P3

156

Q8WZ94
LAWARASALCLNFNC

NOX3

51

Q9HBY0
FVCNWLFCGKRFTRS

SP8

386

Q8IXZ3
FACHLCGQSFRGWVA

REPIN1

116

Q9BWE0
GFFLFLWFCSQRCRS

ADGRG5

496

Q8IZF4
RAFCDVWAAVDVLCC

ADRA1D

166

P25100
IWAAAPNRFCADCGA

ARAP1

541

Q96P48
QPRACACGEAFAWRA

ZNF837

196

Q96EG3
NTRLKWFAICFVCGV

SFT2D1

31

Q8WV19
LLIFQDCAAWFACCL

SLC30A10

131

Q6XR72
LDSQDSGSLCFCFRW

TBC1D17

481

Q9HA65
FSCIWGTFILISENC

TRAM1L1

131

Q8N609
GQVCVWDTRAGRCFL

WDR90

1321

Q96KV7
FECLTCGVAWADARS

ZBTB11

886

O95625
IFQCIECGRNFSWRS

ZNF678

96

Q5SXM1
DCCWVLCALLVFFSD

XKR7

56

Q5GH72
CGFLWATFICFSQQS

MPV17L

156

Q2QL34
CNWLFCGKRFTRSDE

SP7

326

Q8TDD2
SSFLWFAIRCGCSLD

TSPAN32

216

Q96QS1
AQFFSCVSCWDLRGS

TUT1

496

Q9H6E5
VCNWFFCGKRFTRSD

SP2

556

Q02086
VFVAFWACALAVGVC

ATP6V0B

11

Q99437
WACALAVGVCYTIFD

ATP6V0B

16

Q99437
PCDNFFRFACDGWIS

PHEX

76

P78562
IFECICIGWVYGSNR

SLC6A11

481

P48066
WTEAFRCAGNESLLF

SCART1

291

Q4G0T1
ASAVVLRCEGECWLF

ELAC1

21

Q9H777
SNWDFFIVGCEVIFC

PKD2L1

346

Q9P0L9
LAAACAVFLACPWAV

TNFSF9

41

P41273
DFRCAGESCWNAAIA

PHLDA2

81

Q53GA4
RGLFSANDWQCKTCS

ZRANB2

61

O95218
RCEVCGQVFSQAWFL

ZNF536

346

O15090
CVGEDNHWLFLQLCF

ZDHHC21

126

Q8IVQ6
NAWSIIQTDFRCCGV

TSPAN4

136

O14817
LECQFQFRFERWNCT

WNT9A

91

O14904
CEFCGRAFSQGSEWE

ZNF462

2416

Q96JM2
ILCGFQFISCVRGQW

ZDHHC7

191

Q9NXF8
TNVRDAACYVCWAFA

TBCD

461

Q9BTW9
DTWGCFFVCNLLYAL

TM6SF2

331

Q9BZW4
CQFKTCWRAAPEFRA

WNT10B

256

O00744
GWCLEAFSYAQGRCL

TLR5

766

O60602
FLTFWDQCTERLSCF

RIPOR1

971

Q6ZS17
CNKIFAGWDFCITNR

TMC7

306

Q7Z402
PFNCECDLFGFLAWL

ELFN2

186

Q5R3F8
CFTVENADAVCARNW

NALF1

181

B1AL88
TAFVLFCAWCALNSA

PCSK1

11

P29120