Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

SETD1A KMT2D SETD1B

2.18e-068693GO:0140945
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

SETD1A KMT2D SETD1B

4.66e-0610693GO:0140999
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

SETD1A KMT2D SETD1B

4.32e-0520693GO:0042800
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

SOX12 MEF2B KMT2D ERFL NFATC4 ESRRA INSM1 ARX SOX17 PDX1 SIX5 CC2D1B HES1 IRF7 CIC

7.68e-0514126915GO:0000981
GeneOntologyMolecularFunctionhistone methyltransferase activity

SETD1A KMT2D SETD1B PRDM13

1.07e-0471694GO:0042054
GeneOntologyMolecularFunctionchromatin binding

TLE4 POLG INSM1 ARX PDX1 PPP2R3B PRDM13 HES1 CIC MED12

2.14e-047396910GO:0003682
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

SOX12 MEF2B NFATC4 ESRRA INSM1 ARX SOX17 PDX1 SIX5 CC2D1B HES1 IRF7 MED12

2.94e-0412446913GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

SOX12 MEF2B NFATC4 ESRRA INSM1 ARX SOX17 PDX1 SIX5 CC2D1B HES1 IRF7 MED12

3.61e-0412716913GO:0000987
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

SOX12 MEF2B NFATC4 ESRRA INSM1 ARX SOX17 PDX1 SIX5 CC2D1B HES1 IRF7 CIC MED12

3.98e-0414596914GO:0000977
GeneOntologyMolecularFunctionprotein methyltransferase activity

SETD1A KMT2D SETD1B PRDM13

4.46e-04103694GO:0008276
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

SETD1A KMT2D SETD1B

4.73e-0444693GO:0140938
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A1 COL4A2 COL22A1

5.39e-0446693GO:0030020
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

NFATC4 ESRRA INSM1 ARX CC2D1B HES1

8.30e-04320696GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

NFATC4 ESRRA INSM1 ARX CC2D1B HES1

9.14e-04326696GO:0001217
GeneOntologyMolecularFunctionhistone modifying activity

SETD1A KDM5B KMT2D SETD1B PRDM13

1.18e-03229695GO:0140993
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

SETD1A KMT2D SETD1B

1.69e-0368693GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

SETD1A KMT2D SETD1B

1.76e-0369693GO:0016278
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

SOX12 MEF2B KMT2D ESRRA ARX SOX17 SIX5

3.16e-03560697GO:0001228
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

SETD1A SOX17 PRDM13 HES1 ZFPM1 MED12

3.17e-03417696GO:0061629
GeneOntologyMolecularFunctiontranscription coregulator activity

KDM5B KMT2D WTIP TLE4 EWSR1 ZFPM1 MED12

3.22e-03562697GO:0003712
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

SOX12 MEF2B KMT2D ESRRA ARX SOX17 SIX5

3.35e-03566697GO:0001216
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

SETD1A TLE4 SOX17 PRDM13 HES1 ZFPM1 MED12

3.90e-03582697GO:0140297
GeneOntologyMolecularFunctiontranscription factor binding

SETD1A NFATC4 TLE4 SOX17 PRDM13 HES1 ZFPM1 MED12

4.33e-03753698GO:0008134
GeneOntologyMolecularFunctionN-methyltransferase activity

SETD1A KMT2D SETD1B

5.76e-03105693GO:0008170
GeneOntologyMolecularFunctionmethyltransferase activity

SETD1A KMT2D SETD1B PRDM13

6.34e-03213694GO:0008168
GeneOntologyMolecularFunctionprotein serine/threonine phosphatase activity

SSH3 PPP2R3B PHLPP1

6.38e-03109693GO:0004722
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

SOX12 KDM5B WTIP NFATC4 TLE4 ESRRA INSM1 ARX RBM15B PDX1 PRDM13 SIX5 CC2D1B ZFTA HES1 IRF7 ZNF318 ZFPM1 CIC

9.77e-0813996919GO:0045892
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

SOX12 KDM5B WTIP NFATC4 TLE4 ESRRA INSM1 ARX RBM15B PDX1 PRDM13 SIX5 CC2D1B ZFTA HES1 IRF7 ZNF318 ZFPM1 CIC

1.14e-0714136919GO:1902679
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

SOX12 NFATC4 TLE4 ESRRA INSM1 ARX PDX1 PRDM13 CC2D1B HES1 IRF7 ZFPM1 CIC

3.99e-0510536913GO:0000122
GeneOntologyCellularComponentchromatin

SOX12 SETD1A KDM5B MEF2B NFATC4 CPSF6 ESRRA ARX SOX17 PDX1 SIX5 HES1 IRF7 ZFPM1 ZNF385A CIC

1.94e-0514806916GO:0000785
GeneOntologyCellularComponentcollagen type IV trimer

COL4A1 COL4A2

1.60e-046692GO:0005587
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A1 COL4A2

2.97e-048692GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A1 COL4A2

2.97e-048692GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A1 COL4A2

2.97e-048692GO:0098645
GeneOntologyCellularComponentmethyltransferase complex

SETD1A KMT2D SETD1B RBM15B

4.50e-04108694GO:0034708
GeneOntologyCellularComponentnuclear speck

SETD1A SETD1B NFATC4 CPSF6 RBM15B PDX1 SNRNP70

5.41e-04431697GO:0016607
GeneOntologyCellularComponentactin filament bundle

LPP DIAPH3 ZYX PPP1R12C

6.29e-04118694GO:0032432
GeneOntologyCellularComponenttranscription regulator complex

MEF2B WTIP NFATC4 TLE4 INSM1 SOX17 SIX5 ZFPM1

7.55e-04596698GO:0005667
GeneOntologyCellularComponentSet1C/COMPASS complex

SETD1A SETD1B

1.25e-0316692GO:0048188
GeneOntologyCellularComponenthistone methyltransferase complex

SETD1A KMT2D SETD1B

1.96e-0375693GO:0035097
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A1 COL4A2

2.17e-0321692GO:0098644
GeneOntologyCellularComponentcollagen trimer

COL4A1 COL4A2 COL22A1

3.09e-0388693GO:0005581
MousePhenoabnormal pancreas development

COL4A2 INSM1 PDX1 HES1

1.03e-0535554MP:0003934
MousePhenoincreased PP cell number

INSM1 PDX1

1.52e-052552MP:0009185
MousePhenoabnormal pancreatic endocrine progenitor cell physiology

INSM1 PDX1

1.52e-052552MP:0011911
MousePhenoabnormal bile duct development

SOX17 PDX1 HES1

2.54e-0515553MP:0002929
MousePhenoabnormal pancreatic delta cell morphology

INSM1 ARX PDX1

3.11e-0516553MP:0005218
MousePhenopancreatic islet hypoplasia

INSM1 PDX1

9.07e-054552MP:0009169
MousePhenobuphthalmos

COL4A1 COL4A2

9.07e-054552MP:0009274
MousePhenoabnormal pancreatic epsilon cell morphology

INSM1 PDX1

1.51e-045552MP:0009189
MousePhenoabnormal platelet alpha-granule number

ZFPM1 ZNF385A

1.51e-045552MP:0020429
MousePhenodecreased platelet alpha-granule number

ZFPM1 ZNF385A

1.51e-045552MP:0020431
MousePhenoanterior polar cataract

COL4A1 COL4A2

1.51e-045552MP:0010259
MousePhenoabsent pancreas

SOX17 PDX1

1.51e-045552MP:0003655
MousePhenopolar cataract

COL4A1 COL4A2

2.26e-046552MP:0010258
MousePhenoabnormal pancreatic alpha cell number

INSM1 ARX PDX1

3.45e-0435553MP:0020577
MousePhenoabnormal megakaryocyte morphology

DIDO1 ZFPM1 ZNF385A VASP

3.59e-0486554MP:0002417
MousePhenoabnormal PP cell morphology

INSM1 PDX1

4.19e-048552MP:0009184
MousePhenomacrophthalmia

COL4A1 COL4A2

4.19e-048552MP:0001296
DomainHMG_box_dom

SOX12 KMT2D MIA2 SOX17 CIC

3.84e-0665685IPR009071
DomainN-SET

SETD1A SETD1B

1.31e-052682PF11764
DomainCOMPASS_Set1_N-SET

SETD1A SETD1B

1.31e-052682IPR024657
DomainN-SET

SETD1A SETD1B

1.31e-052682SM01291
DomainSET

SETD1A KMT2D SETD1B PRDM13

2.34e-0546684SM00317
DomainPost-SET_dom

SETD1A KMT2D SETD1B

2.50e-0516683IPR003616
DomainPostSET

SETD1A KMT2D SETD1B

2.50e-0516683SM00508
DomainPOST_SET

SETD1A KMT2D SETD1B

2.50e-0516683PS50868
DomainSET_dom

SETD1A KMT2D SETD1B PRDM13

3.26e-0550684IPR001214
DomainSET

SETD1A KMT2D SETD1B PRDM13

3.26e-0550684PS50280
DomainHMG_box

SOX12 KMT2D SOX17 CIC

4.11e-0553684PF00505
DomainHMG

SOX12 KMT2D SOX17 CIC

4.43e-0554684SM00398
Domain-

SOX12 KMT2D SOX17 CIC

4.77e-05556841.10.30.10
DomainRRM_1

SETD1A SETD1B CPSF6 RBM15B EWSR1 SNRNP70

1.09e-04208686PF00076
DomainRRM

SETD1A SETD1B CPSF6 RBM15B EWSR1 SNRNP70

1.38e-04217686SM00360
DomainRRM_dom

SETD1A SETD1B CPSF6 RBM15B EWSR1 SNRNP70

1.76e-04227686IPR000504
DomainRRM

SETD1A SETD1B CPSF6 RBM15B EWSR1 SNRNP70

1.89e-04230686PS50102
DomainC4

COL4A1 COL4A2

1.94e-046682SM00111
Domain-

COL4A1 COL4A2

1.94e-0466822.170.240.10
DomainCollagen_VI_NC

COL4A1 COL4A2

1.94e-046682IPR001442
DomainC4

COL4A1 COL4A2

1.94e-046682PF01413
DomainSPOC_C

RBM15B DIDO1

1.94e-046682IPR012921
DomainNC1_IV

COL4A1 COL4A2

1.94e-046682PS51403
DomainSPOC

RBM15B DIDO1

1.94e-046682PF07744
Domain-

SETD1A SETD1B CPSF6 RBM15B EWSR1 SNRNP70

2.60e-042446863.30.70.330
DomainNucleotide-bd_a/b_plait

SETD1A SETD1B CPSF6 RBM15B EWSR1 SNRNP70

3.51e-04258686IPR012677
DomainSET

SETD1A KMT2D SETD1B

4.46e-0441683PF00856
DomainHMG_BOX_2

SOX12 SOX17 CIC

1.00e-0354683PS50118
DomainZF_MATRIN

ZNF318 ZNF385A

1.92e-0318682PS50171
DomainLIM

WTIP LPP ZYX

2.04e-0369683PF00412
Domain-

WTIP LPP ZYX

2.12e-03706832.10.110.10
DomainZnf_LIM

WTIP LPP ZYX

2.21e-0371683IPR001781
DomainLIM_DOMAIN_1

WTIP LPP ZYX

2.21e-0371683PS00478
DomainLIM_DOMAIN_2

WTIP LPP ZYX

2.21e-0371683PS50023
DomainLIM

WTIP LPP ZYX

2.21e-0371683SM00132
DomainPHD

KDM5B KMT2D DIDO1

2.58e-0375683PF00628
DomainZnf_PHD-finger

KDM5B KMT2D DIDO1

3.00e-0379683IPR019787
DomainCollagen

COL4A1 COL4A2 COL22A1

3.68e-0385683IPR008160
DomainCollagen

COL4A1 COL4A2 COL22A1

3.68e-0385683PF01391
Domain-

SSH3 ARX PDX1 SIX5 TIGD5

3.69e-032836851.10.10.60
DomainPHD

KDM5B KMT2D DIDO1

4.19e-0389683SM00249
DomainZnf_PHD

KDM5B KMT2D DIDO1

4.46e-0391683IPR001965
DomainZnF_U1

ZNF318 ZNF385A

4.98e-0329682SM00451
DomainZnf_U1

ZNF318 ZNF385A

4.98e-0329682IPR003604
DomainZF_PHD_2

KDM5B KMT2D DIDO1

5.03e-0395683PS50016
DomainZF_PHD_1

KDM5B KMT2D DIDO1

5.18e-0396683PS01359
DomainHomeodomain-like

SSH3 ARX PDX1 SIX5 TIGD5

7.20e-03332685IPR009057
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

SETD1A KMT2D SETD1B ZFPM1

1.85e-0544514MM15527
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A1 COL4A2 P3H2 COL22A1

6.81e-0561514MM14637
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A1 COL4A2 P3H2 COL22A1

9.84e-0567514M26999
PathwayREACTOME_COLLAGEN_FORMATION

COL4A1 COL4A2 P3H2 COL22A1

1.61e-0476514MM14573
PathwayREACTOME_COLLAGEN_FORMATION

COL4A1 COL4A2 P3H2 COL22A1

3.09e-0490514M631
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

SETD1A KMT2D SETD1B

3.44e-0438513MM17073
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

SETD1A KMT2D SETD1B ZFPM1

3.95e-0496514M27792
PathwayPID_ECADHERIN_STABILIZATION_PATHWAY

LPP ZYX VASP

4.32e-0441513M232
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A1 COL4A2 COL22A1

4.32e-0441513MM15538
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

INSM1 PDX1 HES1

4.64e-0442513M17541
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

SETD1A KMT2D SETD1B

4.64e-0442513M48018
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

KMT2D TLE4 SOX17

4.64e-0442513M27272
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A1 COL4A2 COL22A1

5.32e-0444513M27812
PathwayBIOCARTA_NPP1_PATHWAY

COL4A1 COL4A2

5.67e-0410512M22040
PathwayBIOCARTA_NPP1_PATHWAY

COL4A1 COL4A2

5.67e-0410512MM1560
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

SETD1A KMT2D SETD1B

6.07e-0446513MM14933
PathwayBIOCARTA_VITCB_PATHWAY

COL4A1 COL4A2

6.91e-0411512M15422
PathwayWP_PTF1A_RELATED_REGULATORY_PATHWAY

PDX1 HES1

6.91e-0411512M39548
PathwayWP_FOCAL_ADHESION

COL4A1 COL4A2 ZYX VASP PPP1R12C

7.39e-04199515M39402
PathwayBIOCARTA_VITCB_PATHWAY

COL4A1 COL4A2

8.28e-0412512MM1526
PathwayBIOCARTA_ACE2_PATHWAY

COL4A1 COL4A2

9.76e-0413512MM1347
PathwayWP_PTF1A_RELATED_REGULATORY_PATHWAY

PDX1 HES1

9.76e-0413512MM15904
PathwayBIOCARTA_ACE2_PATHWAY

COL4A1 COL4A2

9.76e-0413512M12950
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A1 COL4A2

1.14e-0314512MM1458
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A1 COL4A2

1.14e-0314512M6487
PathwayREACTOME_SIGNALING_BY_PDGF

COL4A1 COL4A2 RASA1

1.14e-0357513MM14713
PathwayREACTOME_SIGNALING_BY_PDGF

COL4A1 COL4A2 RASA1

1.20e-0358513M2049
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A1 COL4A2

1.31e-0315512MM14922
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

COL4A1 COL4A2

1.31e-0315512M27161
PathwayWP_HISTONE_MODIFICATIONS

SETD1A KMT2D SETD1B

1.66e-0365513M39374
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A1 COL4A2

1.89e-0318512M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A1 COL4A2

1.89e-0318512MM14882
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

SETD1A KMT2D SETD1B

2.06e-0370513M27231
PathwayREACTOME_SCAVENGING_BY_CLASS_A_RECEPTORS

COL4A1 COL4A2

2.11e-0319512M27221
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

SETD1A KMT2D SETD1B ZFPM1

2.24e-03153514MM15522
PathwayBIOCARTA_AMI_PATHWAY

COL4A1 COL4A2

2.34e-0320512M15394
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A1 COL4A2

2.34e-0320512MM15061
PathwayPID_ECADHERIN_KERATINOCYTE_PATHWAY

ZYX VASP

2.58e-0321512M184
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A1 COL4A2

3.09e-0323512M15997
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A1 COL4A2

3.09e-0323512MM1427
Pubmed

A census of human transcription factors: function, expression and evolution.

SOX12 KMT2D NFATC4 ESRRA INSM1 ARX SOX17 PDX1 SIX5 HES1 IRF7 ZFPM1 ZNF385A CIC

2.53e-09908691419274049
Pubmed

A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for Zfp800 in pancreas development.

INSM1 ARX SOX17 PDX1

8.28e-082169433653874
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

C9orf40 CPSF6 GORASP1 LPP SEC16A SNX18 DIAPH3 SNRNP70 NCKAP5L ZYX VASP MED12 HSPB8

1.14e-071038691326673895
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

INTS5 KMT2D TLE4 ESRRA SEC16A RBM15B DIDO1 ZNF318 ZFPM1 ZYX CIC

3.49e-07774691115302935
Pubmed

Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.

SETD1A KMT2D SETD1B

4.16e-07869323130995
Pubmed

The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.

SETD1A KMT2D SETD1B

4.16e-07869322266653
Pubmed

Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.

SETD1A KMT2D SETD1B

6.22e-07969322665483
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

CPSF6 SEC16A PHLPP1 DIDO1 ZNF318 DIAPH3 KIFC1

7.89e-0725669733397691
Pubmed

Human CpG binding protein interacts with MLL1, MLL2 and hSet1 and regulates Hox gene expression.

SETD1A KMT2D KIFC1

1.22e-061169318082152
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

KDM5B NFATC4 ESRRA SIX5 DIDO1 EWSR1 TIGD5 ZNF318 ZYX CIC

1.34e-06709691022988430
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SETD1A KMT2D LPP SEC16A DIDO1 ZNF318 DIAPH3 ZYX MED12

1.39e-0654969938280479
Pubmed

Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.

SETD1A KMT2D SETD1B

1.62e-061269327563068
Pubmed

Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase.

LPP ZYX VASP

1.62e-061269315465019
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

KMT2D CPSF6 DIDO1 EWSR1 ZNF318 SNRNP70 VARS1 ZYX VASP CIC MED12 KIFC1

1.62e-061103691234189442
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

KDM5B KMT2D TLE4 SEC16A ZNF318 DIAPH3 CIC MED12

1.79e-0641869834709266
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

KMT2D CPSF6 SEC16A ZNF318 DIAPH3 NCKAP5L

1.84e-0618469632908313
Pubmed

Loss of migfilin expression has no overt consequences on murine development and homeostasis.

WTIP LPP ZYX

2.11e-061369321224394
Pubmed

The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity.

WTIP LPP ZYX

2.11e-061369322286099
Pubmed

Sox17 regulates organ lineage segregation of ventral foregut progenitor cells.

SOX17 PDX1 HES1

2.68e-061469319619492
Pubmed

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.

SETD1A KMT2D SETD1B RBM15B

3.05e-065069437974198
Pubmed

The septum transversum mesenchyme induces gall bladder development.

SOX17 PDX1 HES1

3.34e-061569323951403
Pubmed

Type IV procollagen missense mutations associated with defects of the eye, vascular stability, the brain, kidney function and embryonic or postnatal viability in the mouse, Mus musculus: an extension of the Col4a1 allelic series and the identification of the first two Col4a2 mutant alleles.

COL4A1 COL4A2

3.88e-06269217179069
Pubmed

Prevalence of COL4A1 and COL4A2 mutations in severe fetal multifocal hemorrhagic and/or ischemic cerebral lesions.

COL4A1 COL4A2

3.88e-06269232515830
Pubmed

Sequence variants in COL4A1 and COL4A2 genes in Ecuadorian families with keratoconus.

COL4A1 COL4A2

3.88e-06269221527998
Pubmed

Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage.

COL4A1 COL4A2

3.88e-06269239216230
Pubmed

PDX-1/Hes-1 interactions determine cholangiocyte proliferative response to injury in rodents: possible implications for sclerosing cholangitis.

PDX1 HES1

3.88e-06269223207146
Pubmed

Is there relation between COL4A1/A2 mutations and antenatally detected fetal intraventricular hemorrhage?

COL4A1 COL4A2

3.88e-06269224317722
Pubmed

The Col4a2em1(IMPC)Wtsi mouse line: lessons from the Deciphering the Mechanisms of Developmental Disorders program.

COL4A1 COL4A2

3.88e-06269231331924
Pubmed

4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease.

COL4A1 COL4A2

3.88e-06269230351356
Pubmed

Sox17 regulates insulin secretion in the normal and pathologic mouse β cell.

SOX17 PDX1

3.88e-06269225144761
Pubmed

Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly.

COL4A1 COL4A2

3.88e-06269215905400
Pubmed

Association of the CAG repeat polymorphism in mitochondrial polymerase gamma (POLG1) with male infertility: a case-control study in an Algerian population.

POLG MED12

3.88e-06269234077112
Pubmed

Allelic heterogeneity contributes to variability in ocular dysgenesis, myopathy and brain malformations caused by Col4a1 and Col4a2 mutations.

COL4A1 COL4A2

3.88e-06269224203695
Pubmed

Head-to-head arrangement of murine type IV collagen genes.

COL4A1 COL4A2

3.88e-0626923198626
Pubmed

Intracerebral hemorrhage in a neonate with an intragenic COL4A2 duplication.

COL4A1 COL4A2

3.88e-06269233247988
Pubmed

Material-driven fibronectin assembly rescues matrix defects due to mutations in collagen IV in fibroblasts.

COL4A1 COL4A2

3.88e-06269232413593
Pubmed

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.

MEF2B KMT2D

3.88e-06269221796119
Pubmed

NMR studies demonstrate a unique AAB composition and chain register for a heterotrimeric type IV collagen model peptide containing a natural interruption site.

COL4A1 COL4A2

3.88e-06269226209635
Pubmed

Replication of Top Loci From COL4A1/2 Associated With White Matter Hyperintensity Burden in Patients With Ischemic Stroke.

COL4A1 COL4A2

3.88e-06269233148145
Pubmed

The genes for the alpha 1(IV) and alpha 2(IV) chains of human basement membrane collagen type IV are arranged head-to-head and separated by a bidirectional promoter of unique structure.

COL4A1 COL4A2

3.88e-0626922846280
Pubmed

LPP, an actin cytoskeleton protein related to zyxin, harbors a nuclear export signal and transcriptional activation capacity.

LPP VASP

3.88e-06269210637295
Pubmed

Genotype-phenotype correlations in pathology caused by collagen type IV alpha 1 and 2 mutations.

COL4A1 COL4A2

3.88e-06269227794444
Pubmed

Do mutations in COL4A1 or COL4A2 cause thin basement membrane nephropathy (TBMN)?

COL4A1 COL4A2

3.88e-06269217216253
Pubmed

Epilepsy and related challenges in children with COL4A1 and COL4A2 mutations: A Gould syndrome patient registry.

COL4A1 COL4A2

3.88e-06269234735964
Pubmed

Neurologic phenotypes associated with COL4A1/2 mutations: Expanding the spectrum of disease.

COL4A1 COL4A2

3.88e-06269230413629
Pubmed

Next-generation sequencing in a large pedigree segregating visceral artery aneurysms suggests potential role of COL4A1/COL4A2 in disease etiology.

COL4A1 COL4A2

3.88e-06269234281442
Pubmed

The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation.

SETD1A SETD1B

3.88e-06269224550110
Pubmed

Anti-angiogenic collagen fragment arresten is increased from 16 weeks' gestation in pre-eclamptic plasma.

COL4A1 COL4A2

3.88e-06269226343951
Pubmed

Col4a1 mutations cause progressive retinal neovascular defects and retinopathy.

COL4A1 COL4A2

3.88e-06269226813606
Pubmed

Extensive homology between the carboxyl-terminal peptides of mouse alpha 1(IV) and alpha 2(IV) collagen.

COL4A1 COL4A2

3.88e-0626923597383
Pubmed

Alpha 1(IV) and alpha 2(IV) collagen genes are regulated by a bidirectional promoter and a shared enhancer.

COL4A1 COL4A2

3.88e-0626923200851
Pubmed

COL4A2 mutations impair COL4A1 and COL4A2 secretion and cause hemorrhagic stroke.

COL4A1 COL4A2

3.88e-06269222209247
Pubmed

COL4A1 and COL4A2 mutations and disease: insights into pathogenic mechanisms and potential therapeutic targets.

COL4A1 COL4A2

3.88e-06269222914737
Pubmed

Role of α1 and α2 chains of type IV collagen in early fibrotic lesions of idiopathic interstitial pneumonias and migration of lung fibroblasts.

COL4A1 COL4A2

3.88e-06269226006016
Pubmed

TLE4 acts as a corepressor of Hes1 to inhibit inflammatory responses in macrophages.

TLE4 HES1

3.88e-06269229869113
Pubmed

Alternative Lengthening of Telomeres and Differential Expression of Endocrine Transcription Factors Distinguish Metastatic and Non-metastatic Insulinomas.

ARX PDX1

3.88e-06269232103422
Pubmed

In Vivo and In Vitro Characterization of the RNA Binding Capacity of SETD1A (KMT2F).

SETD1A SETD1B

3.88e-06269238003223
Pubmed

Crystal structure of NC1 domains. Structural basis for type IV collagen assembly in basement membranes.

COL4A1 COL4A2

3.88e-06269211970952
Pubmed

A novel sequence in the type IV collagen promoter binds nuclear proteins from Engelbreth-Holm-Swarm tumor.

COL4A1 COL4A2

3.88e-0626921630813
Pubmed

Further refinement of COL4A1 and COL4A2 related cortical malformations.

COL4A1 COL4A2

3.88e-06269230315939
Pubmed

Cutting Edge: The RNA-Binding Protein Ewing Sarcoma Is a Novel Modulator of Lymphotoxin β Receptor Signaling.

EWSR1 LTBR

3.88e-06269231969387
Pubmed

Prenatal clinical manifestations in individuals with COL4A1/2 variants.

COL4A1 COL4A2

3.88e-06269232732225
Pubmed

Identification, purification, and characterization of a zyxin-related protein that binds the focal adhesion and microfilament protein VASP (vasodilator-stimulated phosphoprotein).

ZYX VASP

3.88e-0626927644520
Pubmed

The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link.

COL4A1 COL4A2

3.88e-06269212011424
Pubmed

The structural genes for alpha 1 and alpha 2 chains of human type IV collagen are divergently encoded on opposite DNA strands and have an overlapping promoter region.

COL4A1 COL4A2

3.88e-0626923182844
Pubmed

The arrangement of intra- and intermolecular disulfide bonds in the carboxyterminal, non-collagenous aggregation and cross-linking domain of basement-membrane type IV collagen.

COL4A1 COL4A2

3.88e-0626922844531
Pubmed

Post-translational modification of type IV collagen with 3-hydroxyproline affects its interactions with glycoprotein VI and nidogens 1 and 2.

COL4A1 COL4A2

3.88e-06269229491144
Pubmed

Identification of a novel sequence element in the common promoter region of human collagen type IV genes, involved in the regulation of divergent transcription.

COL4A1 COL4A2

3.88e-0626928317999
Pubmed

Human transcription factor protein interaction networks.

SETD1A KMT2D NFATC4 TLE4 SEC16A SOX17 SIX5 DIDO1 EWSR1 ZNF318 SNRNP70 CIC KIFC1

4.07e-061429691335140242
Pubmed

Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression.

ARX PDX1 HES1

4.11e-061669321856296
Pubmed

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.

SETD1A KMT2D SETD1B

4.11e-061669324368734
Pubmed

New nomenclature for chromatin-modifying enzymes.

SETD1A KDM5B KMT2D SETD1B

5.18e-065769418022353
Pubmed

Neurog3-dependent pancreas dysgenesis causes ectopic pancreas in Hes1 mutant mice.

SOX17 PDX1 HES1

5.97e-061869330093553
Pubmed

NEUROD1 Is Required for the Early α and β Endocrine Differentiation in the Pancreas.

INSM1 ARX PDX1

7.08e-061969334201511
Pubmed

Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas.

ARX PDX1 HES1

8.32e-062069319501159
Pubmed

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.

SETD1A KMT2D SETD1B

8.32e-062069329785026
Pubmed

Expression of Sox transcription factors in the developing mouse pancreas.

SOX12 SOX17 PDX1

9.69e-062169312815626
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SETD1A INTS5 KMT2D ITPRIPL2 SETD1B POLG SEC16A CENPV ZFPM1 CIC MED12

1.07e-051105691135748872
Pubmed

Genetic interaction mapping in mammalian cells using CRISPR interference.

SETD1A KMT2D SETD1B MED12

1.11e-056969428481362
Pubmed

Structural basis for activity regulation of MLL family methyltransferases.

SETD1A KMT2D SETD1B

1.12e-052269326886794
Pubmed

The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.

ARX PDX1 HES1

1.12e-052269327993987
Pubmed

WDR82, a key epigenetics-related factor, plays a crucial role in normal early embryonic development in mice.

SETD1A SETD1B

1.16e-05369221123813
Pubmed

Sertoli cells of the mouse testis originate from the coelomic epithelium.

COL4A1 COL4A2

1.16e-0536929808783
Pubmed

Xist-dependent imprinted X inactivation and the early developmental consequences of its failure.

ARX SOX17

1.16e-05369228134930
Pubmed

Human collagen genes encoding basement membrane alpha 1 (IV) and alpha 2 (IV) chains map to the distal long arm of chromosome 13.

COL4A1 COL4A2

1.16e-0536923025878
Pubmed

VASP, zyxin and TES are tension-dependent members of Focal Adherens Junctions independent of the α-catenin-vinculin module.

ZYX VASP

1.16e-05369226611125
Pubmed

Molecular insight into the SETD1A/B N-terminal region and its interaction with WDR82.

SETD1A SETD1B

1.16e-05369237030068
Pubmed

Elevated TGFβ signaling contributes to cerebral small vessel disease in mouse models of Gould syndrome.

COL4A1 COL4A2

1.16e-05369236435425
Pubmed

Integrated bioinformatics analysis reveals novel key biomarkers and potential candidate small molecule drugs in gastric cancer.

COL4A1 COL4A2

1.16e-05369230975489
Pubmed

Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins.

ZYX VASP

1.16e-05369210801818
Pubmed

Association of polyadenylation cleavage factor I with U1 snRNP.

CPSF6 SNRNP70

1.16e-05369214561889
Pubmed

Functional interaction between COL4A1/COL4A2 and SMAD3 risk loci for coronary artery disease.

COL4A1 COL4A2

1.16e-05369226310581
Pubmed

The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers.

SETD1A SETD1B

1.16e-05369233567280
Pubmed

CUX2/KDM5B/SOX17 Axis Affects the Occurrence and Development of Breast Cancer.

KDM5B SOX17

1.16e-05369235881915
Pubmed

Interaction of osteogenin, a heparin binding bone morphogenetic protein, with type IV collagen.

COL4A1 COL4A2

1.16e-0536922211625
Pubmed

Lysyl hydroxylase 3-mediated post-translational modifications are required for proper biosynthesis of collagen α1α1α2(IV).

COL4A1 COL4A2

1.16e-05369236403858
Pubmed

Type IV collagen alpha-chain composition in synovial lining from trauma patients and patients with rheumatoid arthritis.

COL4A1 COL4A2

1.16e-05369218050191
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

SOX12 MEF2B NFATC4 ESRRA ARX PDX1 HES1 IRF7

1.23e-0554469828473536
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

CPSF6 SEC16A EWSR1 ZNF318 IRGQ SNRNP70 ZYX

1.45e-0539969735987950
Pubmed

Pak3 promotes cell cycle exit and differentiation of β-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice.

INSM1 ARX PDX1

1.47e-052469324163148
InteractionPOLR2A interactions

SETD1A INTS5 KMT2D SETD1B CPSF6 PHLPP1 DIDO1 HES1 EWSR1 SNRNP70 CIC MED12

2.08e-075366812int:POLR2A
InteractionHDAC1 interactions

KDM5B KMT2D TLE4 INSM1 PDX1 PHLPP1 HES1 IRF7 ZNF318 ZFPM1 DIAPH3 SNRNP70 VARS1 CIC MED12

3.27e-0611086815int:HDAC1
InteractionHCFC1 interactions

SETD1A KMT2D SETD1B CPSF6 PHLPP1 DIDO1 CIC

5.81e-05293687int:HCFC1
InteractionFEV interactions

SETD1A KMT2D TLE4 SIX5 CIC KIFC1

6.32e-05203686int:FEV
InteractionKDM1A interactions

KDM5B KMT2D TLE4 INSM1 SEC16A HES1 ZNF318 ZFPM1 DIAPH3 VARS1 CIC MED12

6.51e-059416812int:KDM1A
InteractionPAX9 interactions

KDM5B KMT2D TLE4 EWSR1 CIC

7.78e-05130685int:PAX9
InteractionWDR82 interactions

SETD1A KMT2D SETD1B CPSF6 RBM15B SNRNP70

8.24e-05213686int:WDR82
InteractionCXXC1 interactions

SETD1A KMT2D SETD1B IRF7 KIFC1

8.37e-05132685int:CXXC1
InteractionSMG7 interactions

KMT2D CPSF6 TLE4 SEC16A ZNF318 ZYX VASP

9.88e-05319687int:SMG7
InteractionTRMT2A interactions

RASA1 IRF7 SNRNP70 VASP CIC

1.07e-04139685int:TRMT2A
InteractionFOXC1 interactions

SEC16A SOX17 EWSR1 SNRNP70 VARS1 CIC

1.20e-04228686int:FOXC1
InteractionPHLPP1 interactions

CPSF6 SEC16A PHLPP1 DIDO1 ZNF318 DIAPH3 KIFC1

1.29e-04333687int:PHLPP1
InteractionNCOA6 interactions

SETD1A KMT2D SETD1B SOX17 EWSR1

1.30e-04145685int:NCOA6
InteractionUBP1 interactions

TLE4 EWSR1 VASP CIC

1.47e-0479684int:UBP1
InteractionPHF21A interactions

KMT2D SEC16A ZNF318 DIAPH3 NCKAP5L ZYX CIC

1.55e-04343687int:PHF21A
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ERFL WTIP SIX5 IRGQ SNRNP70 VASP CIC PPP1R12C

4.15e-041192698chr19q13
GeneFamilyRNA binding motif containing

SETD1A SETD1B CPSF6 RBM15B EWSR1 SNRNP70

3.23e-05213526725
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD1A KMT2D SETD1B

1.26e-0434523487
GeneFamilyCollagens

COL4A1 COL4A2 COL22A1

3.12e-0446523490
GeneFamilyLIM domain containing

WTIP LPP ZYX

6.51e-04595231218
GeneFamilySRY-boxes

SOX12 SOX17

1.34e-0319522757
GeneFamilyPHD finger proteins

KDM5B KMT2D DIDO1

2.21e-039052388
GeneFamilyAtaxins|Trinucleotide repeat containing

KMT2D MED12

2.33e-0325522775
CoexpressionGINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN

SETD1A KMT2D RBM15B CC2D1B SNRNP70 NCKAP5L VARS1 CIC PPP1R12C

2.24e-07338689M17094
CoexpressionAMIT_EGF_RESPONSE_480_HELA

COL4A1 COL4A2 P3H2 LTBR ZYX VASP

4.35e-06164686M8729
CoexpressionLIM_MAMMARY_LUMINAL_MATURE_DN

COL4A1 COL4A2 WTIP P3H2 TLE4

4.65e-0694685M2580
CoexpressionLIM_MAMMARY_LUMINAL_MATURE_DN

COL4A1 COL4A2 WTIP P3H2 TLE4

4.89e-0695685MM1328
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPERIC

COL4A1 COL4A2 ITPRIPL2 NFATC4 LPP SNX18 HES1 LTBR ZYX HSPB8 TMBIM1

5.92e-067956811M39050
CoexpressionGSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_DN

COL4A1 COL4A2 KDM5B SNX18 ZYX TMBIM1

1.31e-05199686M7485
CoexpressionYAMAZAKI_TCEB3_TARGETS_UP

COL4A1 COL4A2 LPP SOX17 ZYX

7.24e-05166685M1542
CoexpressionYAMAZAKI_TCEB3_TARGETS_UP

COL4A1 COL4A2 LPP SOX17 ZYX

1.03e-04179685MM660
CoexpressionESC_V6.5_UP_LATE.V1_UP

COL4A1 COL4A2 SOX17 SIX5 ZFPM1

1.18e-04184685M2772
CoexpressionGSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN

TLE4 SOX17 SIX5 VASP FCMR

1.62e-04197685M3438
CoexpressionGSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP

KMT2D TBC1D1 TLE4 SNX18 CIC

1.66e-04198685M7948
CoexpressionGSE27786_NKCELL_VS_NKTCELL_DN

MEF2B INSM1 CENPV ANKRD40 MED12

1.70e-04199685M4852
CoexpressionGSE21670_UNTREATED_VS_TGFB_TREATED_CD4_TCELL_DN

COL4A1 COL4A2 PHLPP1 SIX5 TMBIM1

1.70e-04199685M7472
CoexpressionGSE22589_HEALTHY_VS_HIV_AND_SIV_INFECTED_DC_DN

SETD1B SNX18 DIDO1 ZFTA IRGQ

1.74e-04200685M7796
CoexpressionGSE27786_CD4_TCELL_VS_NKCELL_DN

ITPRIPL2 MIA2 HES1 LTBR DIAPH3

1.74e-04200685M4823
CoexpressionGSE3920_UNTREATED_VS_IFNA_TREATED_FIBROBLAST_DN

KMT2D ABI3 LPP ZFTA FCMR

1.74e-04200685M6687
CoexpressionGSE17721_0.5H_VS_12H_POLYIC_BMDC_UP

ESRRA SEC16A TIGD5 LTBR SNRNP70

1.74e-04200685M4084
CoexpressionGSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_DN

CENPV ZNF318 DIAPH3 VARS1 ZYX

1.74e-04200685M7161
CoexpressionGSE40273_GATA1_KO_VS_WT_TREG_DN

LPP PHLPP1 HES1 VASP MED12

1.74e-04200685M9133
CoexpressionGSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_UP

TBC1D1 SOX17 LTBR ZFPM1 CIC

1.74e-04200685M5630
CoexpressionNABA_COLLAGENS

COL4A1 COL4A2 COL22A1

1.91e-0443683MM17060
CoexpressionNABA_COLLAGENS

COL4A1 COL4A2 COL22A1

2.05e-0444683M3005
ToppCellHippocampus-Endothelial|Hippocampus / BrainAtlas - Mouse McCarroll V32

COL4A1 COL4A2 ITPRIPL2 WTIP NFATC4 SIX5

5.35e-0719269636deadab892d3e639a71f33697bb2d3cbbaa5372
ToppCellThalamus-Endothelial|Thalamus / BrainAtlas - Mouse McCarroll V32

COL4A1 COL4A2 ITPRIPL2 NFATC4 SIX5

1.04e-05186695dcc6e4417c4123d5ca6b96fa8ca4874626aaebdb
ToppCellGlobus_pallidus-Endothelial|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL4A1 COL4A2 ITPRIPL2 NFATC4 HES1

1.12e-05189695ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 COL4A2 SOX17 HES1 HSPB8

1.30e-051956958ab45ab94c722c4aef0229ee1121cd744bf659dd
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

NFATC4 P3H2 TBC1D1 LPP HES1

1.37e-0519769561749ccafeb938c310cff1de5ff924a1c794325a
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

NFATC4 P3H2 TBC1D1 LPP HES1

1.37e-051976959d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell(02)_MMP9/10+-(1)_GFP|(02)_MMP9/10+ / shred by cell type by condition

COL4A1 COL4A2 COL22A1 VARS1 TMBIM1

1.44e-05199695448ba982be804007f991d469eca9d885b21ae499
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABI3 SNX18 ZNF385A ZYX VASP

1.44e-05199695fa5ad81554969fffe5e779614d071d9194a7182c
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_capillary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A1 COL4A2 CRACDL SOX17 HES1

1.47e-052006952d962c9d63e9e5f1a06870e383609672e7b1738c
ToppCelldistal-3-Endothelial-Capillary|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 COL4A2 SOX17 HES1 HSPB8

1.47e-05200695bb792bfe34da99c400993155ffd8e0c15af29c26
ToppCell10x5'v1-week_17-19-Myeloid_monocytic-monocyte-CD14_monocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ABI3 LTBR ZNF385A ZYX VASP

1.47e-0520069507197f95282ee607db17b92fea1376051e65fc50
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Fos_(Layer_2/3,_IEG+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MIA2 PRDM13 FCMR

9.03e-0556693a6a0345ddb9db1441fc048bc4d7b05f625de2ccd
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POLG SOX17 DIAPH3 NCKAP5L

9.84e-051556948e239470799426ea474a36f57e1b7e0d9365ca5f
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 SOX17 IRF7

1.01e-041566940695ac0f02d059ecf813d61d3c9d4c76d1d85834
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 SOX17 IRF7

1.01e-041566941c2920f4356789a9c11d5ea1eaafb18a50b19ed7
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 SOX17 IRF7

1.01e-04156694a45fbe02cd03bd4a097f21368bc1179779ba0db8
ToppCellfacs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D1 TIGD5 KIFC1 FCMR

1.03e-041576940fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCellAT1_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A2 WTIP DIAPH3

1.17e-04162694ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOWAHA GALR1 C9orf40 CIC

1.25e-0416569450f1fa7434ebb777e15d5273d1ff41070cff6db3
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

WTIP P3H2 TBC1D1 LPP

1.25e-04165694f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 ITPRIPL2 RASA1 LTBR

1.44e-041716947c8304573b892ef9ea4e048cba9ea9fbab848dcd
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

WTIP P3H2 TBC1D1 LPP

1.44e-04171694e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A1 COL4A2 NFATC4 LPP

1.50e-04173694f8e3dded726bb3a6c24bfedf8c6732bb46262308
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALR1 INSM1 ARX FCMR

1.54e-04174694ecdff386d7f0bc57c170a2c1f4deae5ba7e431b5
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

COL4A1 COL4A2 SOX17 SIX5

1.54e-04174694fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A1 COL4A2 TBC1D1 LPP

1.57e-041756941125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 COL4A2 SOX17 HES1

1.60e-04176694269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MIA2 RBM15B CENPV TIGD5

1.60e-0417669476fdf211bce101e83a27d822cb399487bd107027
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A1 COL4A2 NFATC4 LPP

1.64e-04177694e65c0568dc5852108e9802273499bc7cf88fafab
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A2 WTIP LPP

1.64e-04177694a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A2 WTIP LPP

1.64e-041776943645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALR1 INSM1 ARX FCMR

1.68e-04178694d3cbdec9d75f076e565baca05ede292cca7758a4
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

COL4A1 COL4A2 DIDO1 ZFTA

1.68e-04178694edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCellEndothelial|World / shred by cell class for turbinate

COL4A1 COL4A2 P3H2 SOX17

1.71e-04179694052b2681974be00efb8503fa4e2c85d91d5ebd06
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

COL4A1 COL4A2 TBC1D1 LPP

1.71e-04179694a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD207+CD1a+_LCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

ABI3 P3H2 ZNF385A VASP

1.75e-04180694289f8c4b53ffd164fee1f459a9315c0deb5f76d0
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A1 COL4A2 CRACDL ZFTA

1.75e-04180694efc4c5a4dea456527526bbfd88cf70d803893671
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2B ZNF318 VARS1 FCMR

1.75e-04180694b51b10781082bc0305ba6a81e978729b329f7771
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 IRF7 TIGD5 SNRNP70

1.79e-04181694709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBC1D1 LPP ZYX HSPB8

1.82e-041826947b86703559438e2d5ef3dad963ee0d772513f313
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3 TBC1D1 IRF7 VASP

1.86e-04183694c12a4603cf81b5736553a4530cea5cefab80556f
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-DC1|lymph-node_spleen / Manually curated celltypes from each tissue

P3H2 LTBR ZNF385A ZYX

1.86e-04183694c9e3d91f4c3395a73295b92e25608e0effb5d241
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-Late_cap|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL4A1 COL4A2 ABI3 SOX17

1.86e-041836943e69cc605f166a1f04e3d077935f7cfd806f1ffd
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A2 P3H2 DIAPH3

1.86e-041836946821dca076318115d360ff426eb1218cfe104063
ToppCelldroplet-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 ABI3 SOX17

1.90e-04184694fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WTIP P3H2 LPP PPP1R12C

1.90e-0418469489ae8bf1a6c2d355d279d23a5e24a08d9ec2334e
ToppCelldroplet-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A1 COL4A2 ABI3 SOX17

1.90e-04184694ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCell(4)_Endothelial_cells-(40)_EC-arterial|World / Cell class and subclass of bone marrow stroma cells in homeostatis

COL4A1 COL4A2 ABI3 SOX17

1.90e-041846947e1a2971321ddcfa00d78d3e3ba7960e532f9392
ToppCelldroplet-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 ABI3 SOX17

1.90e-041846941d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WTIP P3H2 LPP PPP1R12C

1.90e-0418469434c84ac9a32eaf96f45b79485119cad65905817d
ToppCelldroplet-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 ABI3 SOX17

1.90e-0418469476caad53d55fff5acca27bf190a6de7b27437d9f
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A1 COL4A2 ABI3 SOX17

1.90e-041846941fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A1 COL4A2 ABI3 SOX17

1.90e-041846942467207aaea307873ab286f89cfc7668a227a694
ToppCellE12.5-Endothelial-capillary_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A1 COL4A2 ABI3 SOX17

1.94e-04185694e005d3c01a908157f780bbc1d53dd2ed814a39d2
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFATC4 TBC1D1 LPP NCKAP5L

1.94e-0418569438486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCellE12.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A1 COL4A2 ABI3 SOX17

1.94e-041856940bccc424d0466f7f82baa00127c733640a2d50fb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFATC4 TBC1D1 LPP NCKAP5L

1.94e-041856943c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCellIPF-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

COL4A1 COL4A2 WTIP P3H2

1.98e-04186694d436ee6cabbde8553ec5e6e55022274090d9f41a
ToppCellE17.5-Endothelial-unknown_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A1 COL4A2 ABI3 SOX17

2.02e-04187694da885c26ccc5189b1ff1f607552e00a5c0e49e7e
ToppCellCOPD-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

COL4A1 COL4A2 TBC1D1 HES1

2.02e-04187694406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCellE17.5-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A1 COL4A2 ABI3 SOX17

2.02e-041876941f358d02ec69d44dea2e2831af9473ed05dcf8cc
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 LPP ZYX HSPB8

2.02e-041876943912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

COL4A1 COL4A2 WTIP DIAPH3

2.02e-0418769477f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

COL4A2 DIDO1 ZFTA NCKAP5L

2.06e-0418869414bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCellEntopeduncular-Endothelial|Entopeduncular / BrainAtlas - Mouse McCarroll V32

COL4A1 COL4A2 ITPRIPL2 VASP

2.06e-0418869494774652fd42bad5012356672ffac8b6d2c22d37
ToppCellSubstantia_nigra-Endothelial|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

COL4A1 COL4A2 NFATC4 LPP

2.11e-04189694bef8234bd9c4d6e3cdef0791d8066b39ba56ebba
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A1 COL4A2 TBC1D1 VASP

2.11e-0418969426cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

COL4A1 COL4A2 SOX17 HES1

2.11e-041896949a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCellIPF-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

ABI3 TLE4 SNX18 HES1

2.11e-041896945c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCellStriatum-Endothelial|Striatum / BrainAtlas - Mouse McCarroll V32

COL4A1 COL4A2 ITPRIPL2 WTIP

2.11e-0418969495ee3b6d7fbbfcf91c780dfcd0926acec05f0a2d
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

COL4A1 COL4A2 WTIP DIAPH3

2.11e-041896945a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A1 COL4A2 ABI3 SOX17

2.11e-0418969428b9e96a5206b7fdae9b17daf05c8f5d24b6c5ec
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A1 COL4A2 TBC1D1 VASP

2.15e-041906942ab604d35456beba71c25511e0f819000e6642d2
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 COL4A2 RASA1 LPP

2.15e-04190694d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 COL4A2 SOX17 HES1

2.15e-041906946847afca73e1b76c2e86187ccb1a164aefd8f17b
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 COL4A2 SOX17 ZYX

2.15e-04190694a318d80dd5cc33d43048883b0e7844b5aa280aab
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 COL4A2 SOX17 HES1

2.15e-041906942245f61ae0a720db21e29fcd4e910cf590d2655d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A2 P3H2 DIAPH3

2.19e-04191694d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellfacs-BAT-Fat-24m-Endothelial-endothelial_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 SOX17 HES1

2.19e-041916943550a5ed68e723182ddf85b019a6f2525a17bf52
ToppCellfacs-BAT-Fat-24m-Endothelial|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 SOX17 HES1

2.19e-04191694245ce7d1a26f9aa47acd2827b22b997886919832
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A1 COL4A2 TBC1D1 VASP

2.19e-041916942ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCellfacs-BAT-Fat-24m-Endothelial-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 SOX17 HES1

2.19e-0419169412a291918be26cb5d2b185f6a8996f4d23042cf4
ToppCellfacs-Thymus-Epithelium-24m-Endothelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 SOX17 LTBR

2.24e-0419269439afea574725ce0c67afdd79facdb34f819a828d
ToppCellfacs-Thymus-Epithelium-24m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 SOX17 LTBR

2.24e-04192694597db951b1fbc37db22134c3d27d3ec4ceaa85f7
ToppCellfacs-Thymus-Epithelium-24m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 SOX17 LTBR

2.24e-04192694bc275a9eccb1c7a46fd58b15ca5acdd9f7495842
ToppCellE15.5-Endothelial|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A1 COL4A2 ABI3 SOX17

2.24e-0419269488cc7f14d031a0613d032eb01c93e88c72d3938f
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 LPP ZYX HSPB8

2.24e-04192694d0fb6885f023d55a2b7984c99db9c6463258f788
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 COL4A2 ABI3 SOX17

2.24e-041926943c8603f977de34ee0d2bb50635f6722112a6a4db
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A1 COL4A2 LPP ZYX

2.28e-04193694173f1d83133f5ffa88e2a75d28835ad7acd2aa90
ToppCellE15.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A1 COL4A2 ABI3 SOX17

2.28e-041936949f4ffce4e1440b009b0b5947ebf52b12a644704d
ToppCellnormal-na-Myeloid-non-classical_monocyte-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

ABI3 SNX18 HES1 VASP

2.28e-04193694053adc7ed9f997b503e12239a684bb9f5896e10c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 SOX17 HES1

2.28e-04193694e4b440d50ae7391b26924778be6d9d53e0692449
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 SOX17 HES1

2.28e-04193694e523dc5751f6fdcd4fc1a62b1eecd43f6ae79da9
ToppCellIPF-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

COL4A1 COL4A2 SOX17 HSPB8

2.28e-04193694d7750a7575ef257963b7f1c64fa67c52dbff797b
ToppCellE15.5-Endothelial-proliferative_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A1 COL4A2 ABI3 SOX17

2.28e-04193694ed6fc4f731624be702563d7d2f0bf366bec1e042
ToppCellCOPD-Endothelial|COPD / Disease state, Lineage and Cell class

COL4A1 COL4A2 SOX17 HES1

2.28e-04193694093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCellE15.5-Endothelial-capillary_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A1 COL4A2 ABI3 SOX17

2.28e-041936943b3ffba483d114e9036a6fc64895fc37fc19d3e5
ToppCellPND10-Endothelial-Endothelial_blood-vessel|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 COL4A2 SOX17 HES1

2.28e-041936941d8acf81dcbfe81c7a73ce50c9f38fe0cbc74486
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 SOX17 HES1

2.28e-041936941772f2ac217727de63c4a9303881b3a19a6bb0f0
ToppCellE15.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A1 COL4A2 ABI3 SOX17

2.28e-041936941719a741f8458f658e2965853020f485c22d6106
DrugMonobenzone [103-16-2]; Down 200; 20uM; MCF7; HT_HG-U133A

MIA2 C9orf40 CPSF6 TBC1D1 SSH3 HES1

2.16e-051896865312_DN
DrugPropoxycaine hydrochloride [550-83-4]; Down 200; 12uM; PC3; HT_HG-U133A

SOX12 KDM5B SETD1B C9orf40 HSPB8 TMBIM1

2.36e-051926867155_DN
DrugAcetazolamide [59-66-5]; Down 200; 18uM; MCF7; HT_HG-U133A

SOX12 SETD1B MIA2 C9orf40 SSH3 LTBR

2.65e-051966861686_DN
DrugPivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A

SETD1A C9orf40 PHLPP1 ANKRD40 ZYX MED12

2.65e-051966866014_DN
DrugZimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; HL60; HG-U133A

RASA1 CPSF6 GORASP1 DIDO1 IRGQ ANKRD40

2.72e-051976862012_DN
Drugexemestane; Down 200; 0.01uM; MCF7; HG-U133A

SOX12 POLG LTBR ANKRD40 ZYX CIC

2.88e-05199686165_DN
DrugAtropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; MCF7; HT_HG-U133A

SSH3 TLE4 ZNF318 ZYX CIC MED12

2.88e-051996867219_DN
DrugDipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A

COL4A1 COL4A2 SOX12 MIA2 CIC FCMR

2.97e-052006866766_UP
Diseaseintracranial aneurysm (is_implicated_in)

KMT2D SOX17 COL22A1

2.32e-0612663DOID:10941 (is_implicated_in)
Diseaseneurodevelopmental disorder with speech impairment and dysmorphic facies (implicated_via_orthology)

SETD1A SETD1B

4.93e-062662DOID:0070417 (implicated_via_orthology)
DiseaseDevelopmental Porencephaly

COL4A1 COL4A2

4.93e-062662C4082301
DiseasePost-traumatic Porencephaly

COL4A1 COL4A2

4.93e-062662C3698507
DiseaseCongenital porencephaly

COL4A1 COL4A2

4.93e-062662C0302892
DiseasePorencephaly

COL4A1 COL4A2

4.93e-062662C4082173
DiseasePORENCEPHALY, FAMILIAL

COL4A1 COL4A2

4.93e-062662C1867983
DiseaseHEMORRHAGE, INTRACEREBRAL, SUSCEPTIBILITY TO

COL4A1 COL4A2

4.93e-062662C3281105
DiseasePorencephaly, Type 1, Autosomal Dominant

COL4A1 COL4A2

4.93e-062662C4551998
DiseaseHemorrhage, intracerebral, susceptibility to

COL4A1 COL4A2

1.48e-053662cv:C3281105
DiseaseHEMORRHAGE, INTRACEREBRAL, SUSCEPTIBILITY TO

COL4A1 COL4A2

1.48e-053662614519
Diseaselymphocyte:monocyte ratio

CPSF6 TBC1D1 LPP PHLPP1 LTBR VARS1

4.56e-05288666EFO_0600088
DiseasePhyllodes Tumor

KMT2D MED12

4.91e-055662C0010701
DiseaseMalignant Cystosarcoma Phyllodes

KMT2D MED12

4.91e-055662C0600066
DiseaseCerebral Primitive Neuroectodermal Tumor

HES1 EWSR1

1.37e-048662C0751675
DiseaseSpongioblastoma

HES1 EWSR1

1.37e-048662C0334584
DiseaseEpendymoblastoma

HES1 EWSR1

1.37e-048662C0700367
DiseaseMedulloepithelioma

HES1 EWSR1

1.37e-048662C0334596
DiseaseNeuroectodermal Tumor, Primitive

HES1 EWSR1

1.37e-048662C0206663
DiseaseSmall cell carcinoma of lung

COL4A2 INSM1 COL22A1

2.44e-0454663C0149925
Diseaseage at menopause

TLE4 POLG DIDO1 ZFPM1 MED12

5.83e-04302665EFO_0004704
Diseaseneoplasm of mature B-cells

LPP PHLPP1

9.12e-0420662EFO_0000096
Diseaseplatelet crit

COL4A1 COL4A2 P3H2 TLE4 PHLPP1 ZNF318 LTBR ZFPM1

1.25e-03952668EFO_0007985
Diseaseplatelet-to-lymphocyte ratio

TBC1D1 TLE4 LTBR ZFPM1 VARS1

1.32e-03363665EFO_0008446
Diseaseplatelet component distribution width

COL4A1 MIA2 P3H2 LPP EWSR1 LTBR ZFPM1

1.47e-03755667EFO_0007984
Diseasebrain cancer (implicated_via_orthology)

INSM1 HES1

1.55e-0326662DOID:1319 (implicated_via_orthology)
DiseaseNephrotic Syndrome

COL4A1 COL4A2

1.67e-0327662C0027726
DiseaseCerebral Hemorrhage

COL4A1 COL4A2

1.79e-0328662C2937358
Diseasespontaneous coronary artery dissection

COL4A1 COL4A2

2.20e-0331662EFO_0010820

Protein segments in the cluster

PeptideGeneStartEntry
YPRLGPPTPGEPEAP

ZNF385A

241

Q96PM9
PFGGAPGPDAPPLTP

ERFL

151

A0A1W2PQ73
FLPPPFPPPGGDRGR

EWSR1

551

Q01844
PPPYPGGPTAPLLEE

CDIP1

6

Q9H305
PPGLPGPPGPDGFLF

COL4A2

436

P08572
PPLLPPGEPPLLGTF

ANKRD40

161

Q6AI12
FSGPVPPPPPLGFLG

DIAPH3

606

Q9NSV4
GLPGPPGPPGPYDII

COL4A1

1341

P02462
PGPPAPADPLGYLPL

RBM15B

241

Q8NDT2
LEPPGTPGPGPALPL

PPP2R3B

71

Q9Y5P8
ETLGPGGGFPPLPPP

RASA1

126

P20936
DELGLPPPPPGFGPD

ABI3

286

Q9P2A4
EDRNPLYPGPPPPGG

TMBIM1

11

Q969X1
GPGPPAAPPPALDAL

NCKAP5L

166

Q9HCH0
VPAEGRTPPPFPGEP

HSPB8

81

Q9UJY1
LPGEPTPPPGLLLFP

KIFC1

321

Q9BW19
SGEELLALPPPPPPG

PDX1

231

P52945
GPRDGLGPEPQEPPP

ZFPM1

916

Q8IX07
PGGEGDFLPPPPPPL

LPP

61

Q93052
FGAPGPRPPSPFDDP

MED12

626

Q93074
PLGGPGPLGEFLPPP

KDM5B

16

Q9UGL1
AVPPPQGGPPGPFLA

IRF7

146

Q92985
PPPPGEGPGAELPLF

P3H2

96

Q8IVL5
LPDEEKGPPGPAPEP

CRACDL

446

Q6NV74
ALPLGAPPPDALPPG

GORASP1

221

Q9BQQ3
PGPPLGSFPFLPGGP

MEF2B

241

Q02080
PEPPAPEPGPLFGIG

GALR1

16

P47211
DRPPPPVLFPGQPFG

CPSF6

271

Q16630
FAELPVPPGFPPIPG

CC2D1B

436

Q5T0F9
EGPGEPPPPELALLP

CENPV

76

Q7Z7K6
FPGPRGPAPPFPEEN

DIDO1

1771

Q9BTC0
DCPPGPPGLPGLPGF

COL22A1

1116

Q8NFW1
PFVPPPPALDELGGP

ARX

181

Q96QS3
PPPVLPGPGEELPGA

C9orf40

101

Q8IXQ3
PGAEPGYPPEPGDPK

PRDM13

666

Q9H4Q3
EVDPLPFPGPFPAGP

ESRRA

166

P11474
EAPPPVFPLRPGGLP

IRGQ

426

Q8WZA9
RGPGPGPPLPPAAAL

INSM1

181

Q01101
FAPPPPLVPIPGGAA

HES1

181

Q14469
GDGVFLVAPPPPPLP

ITPRIPL2

316

Q3MIP1
GPGFVPPPLAPIRGP

MIA2

1296

Q96PC5
PPDDGPPGELGPDGP

SNRNP70

326

P08621
ALPPPGPEAEPALPG

POLG

156

A0A3B3IS91
PFPPPRLPALEQGPG

VARS1

51

P26640
PEPAGPSIPGLLAPP

SOX17

276

Q9H6I2
PGPGAELDPAAPPPA

PPP1R12C

76

Q9BZL4
PPLPLARDPGSPGPF

NFATC4

301

Q14934
PGLLPNFPAPPPEGL

SIX5

641

Q8N196
LDLGLGPRPPPEPGP

SETD1B

586

Q9UPS6
SPGEGVLGPPPPPRL

INTS5

456

Q6P9B9
PPGGAFGEAFLPFPP

SETD1A

706

O15047
PFPPLPPEPEGGGEE

SSH3

496

Q8TE77
DPEPPGPPDPPVAFG

CIC

511

Q96RK0
LEPSGPGLPPGVPPL

SEC16A

1996

O15027
PEPEPAPFGPPGAAA

SOWAHA

86

Q2M3V2
PVPFPPDALIGPGIP

TLE4

461

Q04727
PPPGPGPAEEGAREP

SOX12

16

O15370
VPPGGFEPLPVAPPA

SNX18

81

Q96RF0
PLEPVCEDGPFGPPP

TBC1D1

696

Q86TI0
GEAPVPGPGAPLPPA

FCMR

331

O60667
TPEPPYPIPEEGDPG

LTBR

381

P36941
EGALGGAFPPPPPPI

ZYX

86

Q15942
FGGPPRAPPADLPLP

PHLPP1

291

O60346
PLPALPLPPGREGGP

WTIP

181

A6NIX2
LPDRAPAPPPPAEGG

TIGD5

216

Q53EQ6
LGEPGPPGVEPPPQL

ZNF318

1721

Q5VUA4
DGQEPGGLALPPPPP

ZFTA

551

C9JLR9
EALEGGGPPPPPALP

VASP

111

P50552
PGPLGPEERPPPAAD

KMT2D

3091

O14686