Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	negative regulation of hepatocyte apoptotic process	CFLAR IGF1R	5.70e-05	8	30	2	GO:1903944
GeneOntologyBiologicalProcess	response to glucocorticoid	CFLAR BMP6 IGF1R AGL	8.17e-05	160	30	4	GO:0051384
GeneOntologyBiologicalProcess	negative regulation of monoatomic ion transport	ATP7A HECW1 HECW2 CNR1	1.06e-04	171	30	4	GO:0043271
GeneOntologyBiologicalProcess	cellular response to iron ion	BMP6 ATP7A	1.12e-04	11	30	2	GO:0071281
GeneOntologyBiologicalProcess	regulation of hepatocyte apoptotic process	CFLAR IGF1R	1.12e-04	11	30	2	GO:1903943
GeneOntologyBiologicalProcess	response to corticosteroid	CFLAR BMP6 IGF1R AGL	1.43e-04	185	30	4	GO:0031960
GeneOntologyBiologicalProcess	positive regulation of steroid hormone biosynthetic process	BMP6 IGF1R	1.58e-04	13	30	2	GO:0090031
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection organization	CFLAR ULK4 IGF1R ATP7A HECW1 HECW2 CNR1	1.70e-04	846	30	7	GO:0120035
GeneOntologyBiologicalProcess	regulation of cell projection organization	CFLAR ULK4 IGF1R ATP7A HECW1 HECW2 CNR1	1.92e-04	863	30	7	GO:0031344
GeneOntologyBiologicalProcess	regulation of neuron projection development	CFLAR ULK4 IGF1R HECW1 HECW2 CNR1	2.15e-04	612	30	6	GO:0010975
GeneOntologyBiologicalProcess	steroid biosynthetic process	BMP6 IGF1R MSMO1 SCARB1	2.28e-04	209	30	4	GO:0006694
GeneOntologyBiologicalProcess	hormone biosynthetic process	BMP6 IGF1R SCARB1	2.36e-04	83	30	3	GO:0042446
GeneOntologyBiologicalProcess	negative regulation of sodium ion transmembrane transporter activity	HECW1 HECW2	2.42e-04	16	30	2	GO:2000650
GeneOntologyBiologicalProcess	negative regulation of sodium ion transmembrane transport	HECW1 HECW2	2.74e-04	17	30	2	GO:1902306
GeneOntologyBiologicalProcess	response to wounding	CFLAR IGF1R ATP7A AP3B1 CYP4F11 SCARB1	3.21e-04	659	30	6	GO:0009611
GeneOntologyBiologicalProcess	pyramidal neuron differentiation	ULK4 ATP7A	3.44e-04	19	30	2	GO:0021859
GeneOntologyBiologicalProcess	positive regulation of hormone biosynthetic process	BMP6 IGF1R	3.44e-04	19	30	2	GO:0046886
GeneOntologyBiologicalProcess	negative regulation of sodium ion transport	HECW1 HECW2	4.64e-04	22	30	2	GO:0010766
GeneOntologyBiologicalProcess	regulation of steroid hormone biosynthetic process	BMP6 IGF1R	5.53e-04	24	30	2	GO:0090030
Domain	HECW_N	HECW1 HECW2	2.67e-06	2	31	2	IPR032348
Domain	HECW_N	HECW1 HECW2	2.67e-06	2	31	2	PF16562
Domain	HECT	HERC6 HECW1 HECW2	1.18e-05	27	31	3	PF00632
Domain	HECTc	HERC6 HECW1 HECW2	1.18e-05	27	31	3	SM00119
Domain	HECT_dom	HERC6 HECW1 HECW2	1.18e-05	27	31	3	IPR000569
Domain	HECT	HERC6 HECW1 HECW2	1.18e-05	27	31	3	PS50237
Domain	WW	HECW1 HECW2	2.75e-03	47	31	2	PF00397
Domain	WW	HECW1 HECW2	2.87e-03	48	31	2	SM00456
Domain	WW_DOMAIN_2	HECW1 HECW2	3.23e-03	51	31	2	PS50020
Domain	WW_DOMAIN_1	HECW1 HECW2	3.23e-03	51	31	2	PS01159
Domain	WW_dom	HECW1 HECW2	3.36e-03	52	31	2	IPR001202
Pubmed	Regulation of upstream binding factor 1 activity by insulin-like growth factor I receptor signaling.	IGF1R UBTF	7.69e-07	2	31	2	15533945
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	HERC6 HECW1 HECW2	1.64e-06	26	31	3	26949039
Pubmed	Dual regulation of upstream binding factor 1 levels by IRS-1 and ERKs in IGF-1-receptor signaling.	IGF1R UBTF	2.31e-06	3	31	2	17443674
Pubmed	Nuclear DNA helicase II (RNA helicase A) binds to an F-actin containing shell that surrounds the nucleolus.	UBTF DHX9	4.61e-06	4	31	2	14729462
Pubmed	Insulin-like growth factor I receptor signaling and nuclear translocation of insulin receptor substrates 1 and 2.	IGF1R UBTF	4.61e-06	4	31	2	12554758
Pubmed	NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.	HECW1 HECW2	7.68e-06	5	31	2	14684739
Pubmed	Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia.	BMP6 IGF1R	1.15e-05	6	31	2	16886151
Pubmed	Sporadic Hirschsprung Disease: Mutational Spectrum and Novel Candidate Genes Revealed by Next-generation Sequencing.	ZFHX3 AGL	1.61e-05	7	31	2	29093530
Pubmed	Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse.	IGF1R ATP7A	2.15e-05	8	31	2	16461637
Pubmed	NEDL2 is an essential regulator of enteric neural development and GDNF/Ret signaling.	HECW1 HECW2	4.21e-05	11	31	2	25555806
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	GRB7 CPSF2 AP3B1 UBTF DHX9	5.55e-05	469	31	5	37314180
Pubmed	NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner.	HECW1 HECW2	6.95e-05	14	31	2	27119228
Pubmed	HERC5/IFI16/p53 signaling mediates breast cancer cell proliferation and migration.	HECW1 UBE2H HECW2	7.15e-05	90	31	3	35671810
Pubmed	Molecular phylogenetics and the origins of placental mammals.	ATP7A CNR1	8.02e-05	15	31	2	11214319
Pubmed	A large-scale candidate gene association study of age at menarche and age at natural menopause.	BMP6 IGF1R CNR1 SCARB1	1.02e-04	275	31	4	20734064
Pubmed	SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.	HECW1 HECW2	1.30e-04	19	31	2	21572392
Pubmed	Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.	HECW1 HECW2	1.60e-04	21	31	2	37005481
Pubmed	Many sequence variants affecting diversity of adult human height.	BMP6 SAMD3 CPSF2	2.81e-04	143	31	3	18391951
Pubmed	Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.	CFLAR CYP4F11	2.86e-04	28	31	2	20689807
Pubmed	Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.	ZFHX3 CNR1	3.08e-04	29	31	2	31491374
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	CPSF2 HECW2 ZMYM6	3.43e-04	153	31	3	10718198
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	AP3B1 UBTF DHX9	3.63e-04	156	31	3	22952844
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	SAMD3 HECW2 AGL ATAD2B DHX9	4.51e-04	736	31	5	29676528
Pubmed	A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo.	MSMO1 SCARB1	5.02e-04	37	31	2	26108225
Pubmed	Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.	ZFHX3 UBTF	5.30e-04	38	31	2	28218735
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	HECW1 HECW2	1.12e-03	36	25	2	823
GeneFamily	Olfactory receptors, family 51	OR51G2 OR51B6	1.68e-03	44	25	2	164
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX3 KDM7A IGF1R UBE2H	5.99e-06	172	31	4	d354424c1f861b6607dfd63b9724f4c237b30275
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	CFLAR ZFHX3 IGF1R UBTF ATAD2B	3.66e-06	175	31	5	1058_DN
Drug	Dorzolamide hydrochloride [130693-82-2]; Down 200; 11uM; HL60; HT_HG-U133A	CFLAR IGF1R AP3B1 SCARB1 DHX9	5.61e-06	191	31	5	6142_DN
Drug	Ketoconazole [65277-42-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A	CFLAR BMP6 ZFHX3 HERC6 UBTF	6.52e-06	197	31	5	5685_DN
Drug	Altretamine [654-05-6]; Down 200; 19uM; MCF7; HT_HG-U133A	CFLAR BMP6 HERC6 UBE2H SCARB1	6.69e-06	198	31	5	5688_DN
Drug	torcetrapib	ATP7A SCARB1 DHX9	1.58e-05	36	31	3	CID000159325
Drug	D04031	CFLAR ATP7A DHX9	2.53e-05	42	31	3	CID011954380
Drug	sorafenib	CFLAR IGF1R ATP7A DHX9	6.07e-05	158	31	4	CID000216239
Drug	PR-350	ATP7A DHX9	6.42e-05	9	31	2	CID000164486
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	CFLAR ZFHX3 IGF1R UBTF	8.06e-05	170	31	4	1050_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	CFLAR ZFHX3 IGF1R UBTF	8.06e-05	170	31	4	7043_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	CFLAR IGF1R HERC6 UBTF	8.06e-05	170	31	4	5260_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	CFLAR IGF1R UBTF ATAD2B	8.82e-05	174	31	4	1659_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	CFLAR ZFHX3 IGF1R UBTF	9.22e-05	176	31	4	981_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	CFLAR ZFHX3 IGF1R UBTF	9.43e-05	177	31	4	6434_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	CFLAR ZFHX3 IGF1R UBTF	9.43e-05	177	31	4	7550_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	CFLAR ZFHX3 UBTF ATAD2B	9.64e-05	178	31	4	4436_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	CFLAR IGF1R UBTF ATAD2B	9.64e-05	178	31	4	1471_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	CFLAR IGF1R UBTF ATAD2B	9.64e-05	178	31	4	1672_DN
Drug	trichostatin A; Down 200; 0.1uM; MCF7; HG-U133A	CFLAR ZFHX3 IGF1R UBTF	9.85e-05	179	31	4	332_DN
Drug	Ketanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; PC3; HT_HG-U133A	CFLAR IGF1R UBTF DHX9	1.21e-04	189	31	4	6649_DN
Drug	Estriol [50-27-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A	CFLAR ZFHX3 UBTF SCARB1	1.26e-04	191	31	4	7220_DN
Drug	Pronethalol hydrochloride [51-02-5]; Down 200; 15uM; MCF7; HT_HG-U133A	CFLAR UBTF ZMYM6 DHX9	1.29e-04	192	31	4	4104_DN
Drug	Forskolin, from Coleus forskohlii; Down 200; 0.5uM; PC3; HT_HG-U133A	CFLAR IGF1R HERC6 ATAD2B	1.29e-04	192	31	4	7104_DN
Drug	Pseudopelletierine hydrochloride [6164-62-1]; Down 200; 21uM; HL60; HG-U133A	CFLAR KDM7A IGF1R ATAD2B	1.32e-04	193	31	4	1774_DN
Drug	Tocopherol (R,S) [10191-41-0]; Down 200; 9.2uM; PC3; HT_HG-U133A	BMP6 ZFHX3 KDM7A SCARB1	1.34e-04	194	31	4	6616_DN
Drug	Biperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; MCF7; HT_HG-U133A	CFLAR KDM7A AP3B1 ZMYM6	1.34e-04	194	31	4	3321_DN
Drug	SB 202190; Down 200; 1uM; MCF7; HT_HG-U133A	CFLAR AP3B1 ZMYM6 DHX9	1.37e-04	195	31	4	7054_DN
Drug	Oxethazaine [126-27-2]; Down 200; 8.6uM; HL60; HG-U133A	IGF1R HECW1 ATAD2B DHX9	1.37e-04	195	31	4	1984_DN
Drug	rhodotorulic acid	GRB7 DHX9	1.39e-04	13	31	2	CID000029337
Drug	Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; PC3; HT_HG-U133A	CFLAR IGF1R HECW1 UBE2H	1.40e-04	196	31	4	5831_UP
Drug	Cyclobenzaprine hydrochloride [6202-23-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A	GRB7 AP3B1 ZMYM6 SCARB1	1.40e-04	196	31	4	4834_DN
Drug	Cholecalciferol [67-97-0]; Down 200; 10.4uM; HL60; HT_HG-U133A	CFLAR AP3B1 UBTF SCARB1	1.40e-04	196	31	4	2436_DN
Drug	Benzthiazide [91-33-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A	CFLAR AP3B1 ZMYM6 DHX9	1.40e-04	196	31	4	3329_DN
Drug	Buflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A	CFLAR AP3B1 ZMYM6 SCARB1	1.40e-04	196	31	4	4840_DN
Drug	pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A	CFLAR BMP6 ZMYM6 DHX9	1.42e-04	197	31	4	5925_UP
Drug	Niridazole [61-57-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A	CFLAR BMP6 AP3B1 ZMYM6	1.42e-04	197	31	4	5682_DN
Drug	Iobenguane sulfate; Down 200; 10.8uM; PC3; HT_HG-U133A	CFLAR ZFHX3 AP3B1 ZMYM6	1.45e-04	198	31	4	7299_DN
Drug	nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A	CFLAR KDM7A AP3B1 CYP4F11	1.45e-04	198	31	4	1648_UP
Drug	Dihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; HL60; HG-U133A	GRB7 KDM7A HECW1 ATAD2B	1.45e-04	198	31	4	1391_UP
Drug	Nitrendipine [39562-70-4]; Down 200; 11uM; MCF7; HT_HG-U133A	BMP6 ZFHX3 CYP4F11 ZMYM6	1.45e-04	198	31	4	5405_DN
Drug	Calciferol [50-14-6]; Up 200; 10uM; MCF7; HT_HG-U133A	CFLAR AP3B1 ZMYM6 SCARB1	1.45e-04	198	31	4	5346_UP
Drug	Homosalate [118-56-9]; Up 200; 15.2uM; PC3; HT_HG-U133A	IGF1R HECW1 CNR1 SCARB1	1.45e-04	198	31	4	3797_UP
Drug	Conessine [546-06-5]; Up 200; 11.2uM; MCF7; HT_HG-U133A	CFLAR KDM7A IGF1R SCARB1	1.48e-04	199	31	4	4777_UP
Drug	Spironolactone [52-01-7]; Down 200; 9.6uM; PC3; HT_HG-U133A	CFLAR BMP6 ZFHX3 HERC6	1.48e-04	199	31	4	5781_DN
Drug	Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; MCF7; HT_HG-U133A	CFLAR ZFHX3 HERC6 SCARB1	1.48e-04	199	31	4	5358_UP
Drug	Nomifensine maleate [32795-47-4]; Down 200; 11.2uM; MCF7; HT_HG-U133A	CFLAR UBTF ZMYM6 SCARB1	1.48e-04	199	31	4	7217_DN
Drug	Antineoplastic Agents	IGF1R MSMO1	1.86e-04	15	31	2	ctd:D000970
Drug	Predenema	ATP7A DHX9	2.13e-04	16	31	2	CID000012422
Drug	SnET2	ATP7A DHX9	2.41e-04	17	31	2	CID006918321
Drug	amelubant	ATP7A DHX9	2.71e-04	18	31	2	CID009604655
Drug	8-Bromo Cyclic Adenosine Monophosphate	CFLAR BMP6 SAMD3 MSMO1 CNR1 SCARB1	2.99e-04	693	31	6	ctd:D015124
Drug	val-mCyd	ATP7A DHX9	3.36e-04	20	31	2	CID006918726
Drug	AM 251	ZMYM6 CNR1 DHX9	3.58e-04	102	31	3	ctd:C103505
Drug	AC1L1G4K	GRB7 ATP7A	3.71e-04	21	31	2	CID000003522
Drug	KRM-1648	ATP7A DHX9	4.07e-04	22	31	2	CID006540558
Drug	AC1Q6NIK	ATP7A DHX9	4.86e-04	24	31	2	CID000065939
Drug	etravirine	ATP7A DHX9	4.86e-04	24	31	2	CID000193962
Drug	AC1L2IZE	ATP7A DHX9	4.86e-04	24	31	2	CID000072928
Drug	ICI 182,780	GRB7 BMP6 IGF1R DHX9	4.86e-04	272	31	4	CID000104741
Drug	conivaptan	ATP7A DHX9	5.28e-04	25	31	2	CID000151171
Drug	LB80380	ATP7A DHX9	5.28e-04	25	31	2	CID006480442
Drug	VX-497	ATP7A DHX9	6.17e-04	27	31	2	CID000153241
Drug	Caspofungin [inn]	ATP7A DHX9	6.17e-04	27	31	2	CID000151068
Drug	ValboroPro	ATP7A DHX9	6.63e-04	28	31	2	CID006918572
Drug	dichloromethanediamine	CFLAR IGF1R ATP7A HECW1 UBTF	7.45e-04	539	31	5	CID005311048
Drug	inogatran	ATP7A DHX9	7.62e-04	30	31	2	CID000066005
Drug	pentazocine HCl	ATP7A CNR1	9.80e-04	34	31	2	CID000004736
Drug	dronedarone	ATP7A DHX9	1.10e-03	36	31	2	CID000208898
Drug	AK602	ATP7A DHX9	1.16e-03	37	31	2	CID000464989
Drug	ethylnylestradiol	CFLAR BMP6 IGF1R MSMO1 CYP4F11 UBTF SCARB1	1.22e-03	1251	31	7	CID000003285
Drug	treprostinil sodium	ATP7A DHX9	1.22e-03	38	31	2	CID000054786
Drug	Anisomycin [22862-76-6]; Up 200; 15uM; HL60; HT_HG-U133A	BMP6 UBE2H ATAD2B	1.25e-03	157	31	3	1304_UP
Drug	liarozole	ATP7A DHX9	1.29e-03	39	31	2	CID000060652
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	CFLAR ZFHX3 UBTF	1.35e-03	161	31	3	4768_DN
Disease	age at diagnosis, type 1 diabetes mellitus	SEC14L3 GRB7 HECW1	3.44e-05	62	30	3	EFO_0004918, MONDO_0005147
Disease	Cannabis Abuse	CNR1 SCARB1	4.47e-05	10	30	2	C0006868
Disease	Cannabis-Related Disorder	CNR1 SCARB1	4.47e-05	10	30	2	C0236735
Disease	Hashish Abuse	CNR1 SCARB1	4.47e-05	10	30	2	C0018614
Disease	diabetic neuropathy (implicated_via_orthology)	IGF1R CNR1	9.02e-05	14	30	2	DOID:9743 (implicated_via_orthology)
Disease	sexual dimorphism measurement	ULK4 BMP6 ZFHX3 IGF1R AP3B1 SCARB1 ATAD2B	9.74e-05	1106	30	7	EFO_0021796
Disease	Cannabis Dependence	CNR1 SCARB1	1.35e-04	17	30	2	C0006870
Disease	diabetes mellitus (implicated_via_orthology)	BMP6 IGF1R	3.20e-04	26	30	2	DOID:9351 (implicated_via_orthology)
Disease	Marijuana Abuse	CNR1 SCARB1	4.27e-04	30	30	2	C0024809
Disease	body surface area	ULK4 BMP6 ZFHX3 IGF1R AP3B1	4.39e-04	643	30	5	EFO_0022196
Disease	Growth Disorders	IGF1R ATP7A	6.16e-04	36	30	2	C0018273
Disease	Developmental delay (disorder)	IGF1R UBTF	6.51e-04	37	30	2	C0424605
Disease	breast cancer (is_marker_for)	BMP6 ZFHX3 IGF1R	8.69e-04	185	30	3	DOID:1612 (is_marker_for)
Disease	hemolysis	UBTF ATAD2B	1.05e-03	47	30	2	EFO_0009473
Disease	forced expiratory volume	BMP6 AP3B1 AGL SCARB1 ATAD2B	1.10e-03	789	30	5	EFO_0004314
Disease	vital capacity	BMP6 ZFHX3 IGF1R AP3B1 SCARB1 ATAD2B	1.33e-03	1236	30	6	EFO_0004312
Disease	obesity (implicated_via_orthology)	BMP6 ZFHX3 CNR1	1.34e-03	215	30	3	DOID:9970 (implicated_via_orthology)
Disease	body weight	ULK4 BMP6 ZFHX3 IGF1R CPSF2 AP3B1	1.48e-03	1261	30	6	EFO_0004338
Disease	Alzheimer's disease (biomarker_via_orthology)	IGF1R ATP7A	1.59e-03	58	30	2	DOID:10652 (biomarker_via_orthology)
Disease	insulin resistance	AP3B1 MSMO1	1.65e-03	59	30	2	EFO_0002614
Disease	obsolete_red blood cell distribution width	BMP6 IGF1R AP3B1 HECW2 SCARB1 ATAD2B	2.07e-03	1347	30	6	EFO_0005192
Disease	tissue plasminogen activator measurement, coronary artery disease	SEC14L3 SCARB1	2.38e-03	71	30	2	EFO_0001645, EFO_0004791
Disease	esophagus squamous cell carcinoma (is_marker_for)	GRB7 BMP6	2.58e-03	74	30	2	DOID:3748 (is_marker_for)
Disease	Lung diseases	IGF1R AP3B1	2.86e-03	78	30	2	C0024115
Disease	phosphatidylcholine measurement	ZFHX3 ZMYM6 SCARB1	2.96e-03	284	30	3	EFO_0010226

Protein segments in the cluster

Peptide	Gene	Start	Entry
FDLMKCFQIYPGGKP	ZNF354C	201	Q86Y25
GSFFKQAKKSYPMFP	CPSF2	451	Q9P2I0
FFCFMQDLPPLKYDP	AADACL3	71	Q5VUY0
PYLAGKPKMFFIQNY	CFLAR	346	O15519
YFFPRQPCIFGDKMV	AP3B1	886	O00203
AMGFPAFVKKQPKYL	ATP7A	231	Q04656
GLKKGMFFNPDPYLK	HECW2	196	Q9P2P5
CLPGFLFQFIPYMKK	MSMO1	66	Q15800
EPFPKMLGLLVCFYN	OTOA	336	Q7RTW8
FPKPFVQKYCLMGVQ	KDM7A	261	Q6ZMT4
GLKKGMFFNPDPYLK	HECW1	216	Q76N89
FEKFKIQPPRGCLFY	ATAD2B	426	Q9ULI0
IKAGKMYFAFNPKLC	IGF1R	441	P08069
FPPFMNPFIYSIKTK	OR51B6	281	Q9H340
IFPLPFMLKRFPYCG	OR51G2	161	Q8NGK0
PKPEKKRYFLFGMLC	HERC6	751	Q8IVU3
KLYGMPTDFGFCVKP	GRB7	291	Q14451
AVAPKDMIFYGFLKP	CYP4F11	116	Q9HBI6
GPYDKQPFMVAFFKV	BMP6	351	P22004
LMIPAKDGVKLPYFF	ADA2	341	Q9NZK5
DMASKLGYFPQKFPL	CNR1	36	P21554
KLFPVGYNLMKPFLS	SEC14L3	196	Q9UDX4
MKYPSPFFVFGEKIR	DHX9	1036	Q08211
KLFPFLKCPYQMFRE	SAMD3	331	Q8N6K7
INKYFPGMFPFKDKF	SCARB1	191	Q8WTV0
YPFKSPSIGFMNKIF	UBE2H	61	P62256
PELLFYKGKMFLFCG	ZMYM6	441	O95789
FPKKPLTPYFRFFME	UBTF	111	P17480
GCLLYEMFSGKPPFF	ULK4	206	Q96C45
GFVLYGKRKPILMCF	ZFHX3	271	Q15911
MFFYLKQIPRYLIPC	AGL	991	P35573