Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionfibroblast growth factor receptor activity

FGFR1 FGFR3 FGFR4

1.57e-0651093GO:0005007
GeneOntologyMolecularFunctionfibroblast growth factor binding

KL FGFR1 FGFR3 FGFR4

1.34e-05271094GO:0017134
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

ERBB2 NRP2 FGFR1 FGFR3 FGFR4

2.81e-05651095GO:0004714
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

ERBB2 NRP2 FGFR1 FGFR3 FGFR4

1.02e-04851095GO:0019199
GeneOntologyMolecularFunctiongrowth factor binding

ERBB2 NRP2 KL FGFR1 FGFR3 FGFR4

2.16e-041561096GO:0019838
GeneOntologyMolecularFunctionferric-chelate reductase (NADPH) activity

STEAP1B STEAP1

2.92e-0451092GO:0052851
GeneOntologyMolecularFunctionferric-chelate reductase activity

STEAP1B STEAP1

2.92e-0451092GO:0000293
GeneOntologyMolecularFunctioncupric reductase (NADH) activity

STEAP1B STEAP1

2.92e-0451092GO:0008823
GeneOntologyMolecularFunctioncholesterol transfer activity

CETP GRAMD1A GRAMD1C

2.95e-04241093GO:0120020
GeneOntologyMolecularFunctionsterol transfer activity

CETP GRAMD1A GRAMD1C

3.33e-04251093GO:0120015
GeneOntologyMolecularFunctiontransporter activity

TPTE ABCA2 XKR9 RASA3 CETP TRPC1 GRAMD1A SLC44A2 GRIA4 XKR4 SLC3A2 SLC25A32 SCN10A TRPV2 SV2C SLC35F2 GRAMD1C

6.04e-04128910917GO:0005215
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions, NAD or NADP as acceptor

STEAP1B STEAP1

6.09e-0471092GO:0016723
GeneOntologyMolecularFunctionlipid transporter activity

ABCA2 XKR9 CETP GRAMD1A XKR4 GRAMD1C

7.26e-041961096GO:0005319
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

ERBB2 NRP2 FGFR1 FGFR3 FGFR4

1.20e-031451095GO:0004713
GeneOntologyMolecularFunctionphosphoric ester hydrolase activity

TPTE PTPRU FAM83B PPP2R5A PTPRN2 PDE8B PLCG2 PIP4P2

1.26e-033861098GO:0042578
GeneOntologyMolecularFunctionNAD(P)H oxidase H2O2-forming activity

KMO NOX1

1.88e-03121092GO:0016174
GeneOntologyBiologicalProcessregulation of neuron differentiation

RELN BRINP1 NOX1 ASPM BRINP2 FGFR1 FGFR3 NEUROG2 NEUROG3 CNTN2 WDR62

9.97e-0825510811GO:0045664
GeneOntologyBiologicalProcessaxon ensheathment in central nervous system

ABCA2 ULK4 FGFR3 MYRF CNTN2

7.57e-07331085GO:0032291
GeneOntologyBiologicalProcesscentral nervous system myelination

ABCA2 ULK4 FGFR3 MYRF CNTN2

7.57e-07331085GO:0022010
GeneOntologyBiologicalProcesspositive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

KL FGFR1 FGFR3

2.76e-0661083GO:0090080
GeneOntologyBiologicalProcessoligodendrocyte development

ABCA2 ULK4 FGFR3 MYRF CNTN2

1.43e-05591085GO:0014003
GeneOntologyBiologicalProcessneuron migration

RELN NRP2 ASPM ULK4 FGFR1 NEUROG2 CNTN2 WDR62

1.95e-052181088GO:0001764
GeneOntologyBiologicalProcessforebrain development

RELN RRM1 NRP2 ASPM ULK4 FGFR1 FGFR3 NEUROG2 NEUROG3 CNTN2 WDR62

5.18e-0548910811GO:0030900
GeneOntologyBiologicalProcessoligodendrocyte differentiation

ERBB2 ABCA2 ULK4 FGFR3 MYRF CNTN2

8.45e-051371086GO:0048709
GeneOntologyBiologicalProcessneutrophil extravasation

PRTN3 PIK3CG FUT7

1.08e-04181083GO:0072672
GeneOntologyBiologicalProcesscentral nervous system development

ERBB2 RELN ABCA2 BRINP1 RRM1 NRP2 ASPM BRINP2 ULK4 SNTG2 FGFR1 FGFR3 NEUROG2 MYRF NEUROG3 CNTN2 WDR62

1.57e-04119710817GO:0007417
GeneOntologyBiologicalProcessalveolar secondary septum development

FGFR3 FGFR4

1.62e-0441082GO:0061144
GeneOntologyBiologicalProcesspositive regulation of parathyroid hormone secretion

FGFR1 FGFR4

1.62e-0441082GO:2000830
GeneOntologyBiologicalProcesscentral nervous system neuron development

BRINP1 NRP2 FGFR1 NEUROG2 CNTN2

1.73e-04991085GO:0021954
GeneOntologyBiologicalProcessglial cell development

ERBB2 ABCA2 ULK4 FGFR3 MYRF CNTN2

1.78e-041571086GO:0021782
GeneOntologyBiologicalProcessphosphatidylinositol-mediated signaling

PIK3CG FGFR1 PLCG2

2.61e-04241083GO:0048015
GeneOntologyBiologicalProcessiron ion import across cell outer membrane

STEAP1B STEAP1

2.69e-0451082GO:0098706
GeneOntologyBiologicalProcessregulation of parathyroid hormone secretion

FGFR1 FGFR4

2.69e-0451082GO:2000828
HumanPhenoCloverleaf skull

EXTL3 FGFR1 FGFR3

1.49e-058343HP:0002676
MousePhenoabnormal neuronal precursor cell number

ERBB2 BRINP1 ASPM NEUROG2 WDR62

1.14e-0552805MP:0004979
MousePhenoabnormal sensory neuron innervation pattern

ERBB2 RELN NRP2 TENM3 FGFR3 CNTN2

1.40e-0592806MP:0000968
MousePhenodecreased neuronal precursor cell number

ERBB2 ASPM NEUROG2 WDR62

5.69e-0537804MP:0004981
MousePhenolong incisors

WWP2 FGFR1 FGFR3

9.58e-0516803MP:0004831
MousePhenomacrodontia

WWP2 FGFR1 FGFR3

9.58e-0516803MP:0030091
MousePhenoincreased hair follicle number

PPP2R5A CUX1

9.67e-053802MP:0012110
MousePhenoabnormal cell motility

TPTE ERBB2 RELN DNAH10 NRP2 NOX1 PIK3CG ASPM TRPV2 FGFR1 PLCG2 FUT7 NEUROG2 WDR62 BRWD1

1.28e-048858015MP:0020846
DomainFGF_rcpt_fam

FGFR1 FGFR3 FGFR4

7.70e-0741093IPR016248
DomainC2_dom

TPTE RASA3 WWP2 FER1L6 WWC2 PIK3CG HECW2 PLCG2

5.33e-061641098IPR000008
Domain-

RASA3 WWP2 FER1L6 WWC2 PIK3CG HECW2 PLCG2

2.58e-0514810972.60.40.150
DomainFerric_reduct

NOX1 STEAP1B STEAP1

4.09e-05121093PF01794
DomainFe3_Rdtase_TM_dom

NOX1 STEAP1B STEAP1

4.09e-05121093IPR013130
DomainBRINP

BRINP1 BRINP2

1.01e-0431092IPR033237
DomainDUF4782

GRAMD1A GRAMD1C

1.01e-0431092IPR031968
DomainVAST

GRAMD1A GRAMD1C

1.01e-0431092PS51778
DomainDUF4782

GRAMD1A GRAMD1C

1.01e-0431092PF16016
DomainC2

RASA3 WWP2 FER1L6 WWC2 HECW2 PLCG2

1.85e-041421096PS50004
DomainConA-like_dom

PAPPA2 COL12A1 TSPEAR PTPRU NRP2 FAT1 BTN1A1

3.00e-042191097IPR013320
DomainLongin

SEC22A SEC22C

3.34e-0451092PF13774
Domain-

SEC22A SEC22C

3.34e-04510923.30.450.50
DomainLongin

SEC22A SEC22C

3.34e-0451092SM01270
DomainLongin_dom

SEC22A SEC22C

3.34e-0451092IPR010908
DomainLONGIN

SEC22A SEC22C

3.34e-0451092PS50859
DomainHECT

WWP2 HECW2 HERC2

5.11e-04271093PF00632
DomainHECTc

WWP2 HECW2 HERC2

5.11e-04271093SM00119
DomainHECT_dom

WWP2 HECW2 HERC2

5.11e-04271093IPR000569
DomainHECT

WWP2 HECW2 HERC2

5.11e-04271093PS50237
DomainC2

RASA3 WWP2 FER1L6 HECW2 PLCG2

1.03e-031311095PF00168
DomainPH

RASA3 RALGPS2 PLEKHH1 PLEKHM2 SNTG2 PLCG2 ARHGAP21

1.23e-032781097SM00233
DomainC2

RASA3 WWP2 FER1L6 HECW2 PLCG2

1.25e-031371095SM00239
DomainPH_DOMAIN

RASA3 RALGPS2 PLEKHH1 PLEKHM2 SNTG2 PLCG2 ARHGAP21

1.25e-032791097PS50003
DomainPH_domain

RASA3 RALGPS2 PLEKHH1 PLEKHM2 SNTG2 PLCG2 ARHGAP21

1.28e-032801097IPR001849
DomainMAC_perforin

BRINP1 BRINP2

1.47e-03101092IPR001862
DomainTyr_kinase_cat_dom

ERBB2 FGFR1 FGFR3 FGFR4

1.76e-03881094IPR020635
DomainTyrKc

ERBB2 FGFR1 FGFR3 FGFR4

1.76e-03881094SM00219
DomainTRP_channel

TRPC1 TRPV2

1.79e-03111092IPR004729
DomainXK-related

XKR9 XKR4

1.79e-03111092PF09815
DomainMACPF

BRINP1 BRINP2

1.79e-03111092PF01823
DomainXK_rel

XKR9 XKR4

1.79e-03111092IPR018629
DomainMACPF

BRINP1 BRINP2

2.14e-03121092IPR020864
DomainMACPF

BRINP1 BRINP2

2.14e-03121092SM00457
DomainPH

RASA3 RALGPS2 PLEKHH1 PLEKHM2 PLCG2 ARHGAP21

2.26e-032291096PF00169
DomainPROTEIN_KINASE_TYR

ERBB2 FGFR1 FGFR3 FGFR4

2.51e-03971094PS00109
DomainTyr_kinase_AS

ERBB2 FGFR1 FGFR3 FGFR4

2.51e-03971094IPR008266
DomainWW

WWP2 WWC2 HECW2

2.60e-03471093PF00397
DomainWW

WWP2 WWC2 HECW2

2.76e-03481093SM00456
DomainIg-like_fold

PAPPA2 SEMA4B COL12A1 MMP23B PTPRU CD1D BTN1A1 FGFR1 FGFR3 FGFR4 CNTN2

2.78e-0370610911IPR013783
DomainWW_DOMAIN_1

WWP2 WWC2 HECW2

3.29e-03511093PS01159
DomainWW_DOMAIN_2

WWP2 WWC2 HECW2

3.29e-03511093PS50020
DomainWW_dom

WWP2 WWC2 HECW2

3.47e-03521093IPR001202
DomainGRAM

GRAMD1A GRAMD1C

3.84e-03161092SM00568
DomainMAM

PTPRU NRP2

4.33e-03171092SM00137
DomainIon_trans_dom

TPTE TRPC1 SCN10A TRPV2

4.48e-031141094IPR005821
DomainIon_trans

TPTE TRPC1 SCN10A TRPV2

4.48e-031141094PF00520
DomainLaminin_G

COL12A1 TSPEAR FAT1

4.73e-03581093IPR001791
DomainMAM

PTPRU NRP2

4.86e-03181092PF00629
DomainMAM_dom

PTPRU NRP2

4.86e-03181092IPR000998
DomainMAM_2

PTPRU NRP2

4.86e-03181092PS50060
Domain-

PAPPA2 COL12A1 MMP23B PTPRU CD1D BTN1A1 FGFR1 FGFR3 FGFR4 CNTN2

5.40e-03663109102.60.40.10
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL

ERBB2 FGFR1 FGFR3 FGFR4

1.00e-0525784M47934
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

ERBB2 FGFR1 FGFR3 PLCG2 FGFR4

1.28e-0555785M47952
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

ERBB2 KL PPP2R5A FGFR1 FGFR3 FGFR4

3.73e-05113786MM14783
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

ERBB2 KL PPP2R5A FGFR1 FGFR3 FGFR4

4.76e-05118786M713
PathwayWP_HEAD_AND_NECK_SQUAMOUS_CELL_CARCINOMA

ERBB2 FAT1 PIK3CG FGFR1 FGFR3

5.45e-0574785M39857
PathwayREACTOME_IRS_MEDIATED_SIGNALLING

KL FGFR1 FGFR3 FGFR4

7.52e-0541784MM14505
PathwayREACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER

ERBB2 KL FGFR1 FGFR3 FGFR4

9.44e-0583785M27163
PathwayREACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R

KL FGFR1 FGFR3 FGFR4

1.29e-0447784MM14885
PathwayREACTOME_IRS_MEDIATED_SIGNALLING

KL FGFR1 FGFR3 FGFR4

1.40e-0448784M26916
PathwayREACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE

KL FGFR1 FGFR3 FGFR4

1.40e-0448784MM15441
PathwayREACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R

KL FGFR1 FGFR3 FGFR4

2.22e-0454784M27168
PathwayREACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE

KL FGFR1 FGFR3 FGFR4

2.22e-0454784M620
PathwayREACTOME_PI3K_AKT_SIGNALING_IN_CANCER

ERBB2 KL FGFR1 FGFR3 FGFR4

3.54e-04110785M27162
PathwayREACTOME_SIGNALING_BY_FGFR_IN_DISEASE

FGFR1 FGFR3 FGFR4 CUX1

4.03e-0463784M635
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

ERBB2 WWP2 KL PPP2R5A FGFR1 FGFR3 FGFR4

4.81e-04252787MM15585
PathwayREACTOME_NRCAM_INTERACTIONS

NRP2 CNTN2

6.23e-047782M27378
PathwayKEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY

FGFR1 FGFR3 FGFR4

6.55e-0431783M47396
PathwayREACTOME_SIGNALING_BY_INSULIN_RECEPTOR

KL FGFR1 FGFR3 FGFR4

8.23e-0476784MM15442
PathwayREACTOME_SIGNALING_BY_FGFR

KL FGFR1 FGFR3 FGFR4

8.64e-0477784MM14722
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

GRIA4 KMO SLC25A32 DLGAP3 NOX1 SCN10A PLCG2 CNTN2

9.37e-04367788M48346
PathwayKEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY

FGFR1 FGFR3 FGFR4

9.39e-0435783M47379
PathwayREACTOME_SIGNALING_BY_INSULIN_RECEPTOR

KL FGFR1 FGFR3 FGFR4

1.09e-0382784M1021
PathwayWP_GLIOBLASTOMA_SIGNALING

ERBB2 PIK3CG FGFR1 PLCG2

1.14e-0383784M39637
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY

ERBB2 FGFR1 FGFR3 FGFR4

1.14e-0383784M47961
Pubmed

Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.

KL FGFR1 FGFR3 FGFR4

4.72e-105110428094278
Pubmed

FGFR3 and FGFR4 do not mediate renal effects of FGF23.

KL FGFR1 FGFR3 FGFR4

1.41e-096110418753255
Pubmed

Regulation of fibroblast growth factor-23 signaling by klotho.

KL FGFR1 FGFR3 FGFR4

1.41e-096110416436388
Pubmed

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.

KL FGFR1 FGFR3 FGFR4

1.41e-096110419966287
Pubmed

Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism.

KL FGFR1 FGFR3 FGFR4

1.41e-096110429720668
Pubmed

FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development.

RELN FGFR1 FGFR3 FGFR4 NEUROG2

1.46e-0825110518625063
Pubmed

Differential expression of the fibroblast growth factor receptor (FGFR) multigene family in normal human adult tissues.

FGFR1 FGFR3 FGFR4

1.23e-07411039212826
Pubmed

FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer.

FGFR1 FGFR3 FGFR4

1.23e-074110336142417
Pubmed

Immunohistochemical detection of fibroblast growth factor receptors in normal endocrine cells and related tumors of the digestive system.

FGFR1 FGFR3 FGFR4

1.23e-074110311759058
Pubmed

Differential expression of fibroblast growth factor receptors in the developing murine choroid plexus.

FGFR1 FGFR3 FGFR4

1.23e-074110312644244
Pubmed

Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9.

FGFR1 FGFR3 FGFR4

1.23e-07411039664689
Pubmed

Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients.

FGFR1 FGFR3 FGFR4

1.23e-074110327154171
Pubmed

Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin.

FGFR1 FGFR3 FGFR4

1.23e-074110312373339
Pubmed

The FGF system has a key role in regulating vascular integrity.

FGFR1 FGFR3 FGFR4

1.23e-074110318776942
Pubmed

RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector.

FGFR1 FGFR3 FGFR4

1.23e-074110317304337
Pubmed

Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice.

KL FGFR1 FGFR3 FGFR4

1.67e-0716110424470103
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

SEMA4B ERBB2 ABCA2 COL12A1 GOLM2 GRAMD1A PTDSS1 EXTL3 RRM1 SLC3A2 NRP2 NXPE3 FAT1 TENM3 FGFR4 ARHGAP21 WDR62

2.36e-0712011101735696571
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

SEMA4B ERBB2 VPS39 GOLM2 WWP2 EXTL3 NRP2 FAT1 MROH1 C15orf61 FGFR1 STEAP1B RAB2A PIP4P2 MYRF CUX1

2.40e-0710611101633845483
Pubmed

Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity.

RELN NEUROG2 CUX1 CNTN2

2.80e-0718110427320921
Pubmed

Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.

FGFR1 FGFR3 FGFR4

3.06e-075110315987787
Pubmed

The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes.

FGFR1 FGFR3 FGFR4

3.06e-075110327078042
Pubmed

Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors.

FGFR1 FGFR3 FGFR4

3.06e-075110316091423
Pubmed

FGF-dependent regulation of VEGF receptor 2 expression in mice.

FGFR1 FGFR3 FGFR4

3.06e-075110321633168
Pubmed

FGF23 induced left ventricular hypertrophy mediated by FGFR4 signaling in the myocardium is attenuated by soluble Klotho in mice.

KL FGFR1 FGFR4

3.06e-075110331758962
Pubmed

Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands.

FGFR1 FGFR3 FGFR4

3.06e-075110327206683
Pubmed

Expression of fibroblast growth factor receptors in peri-implantation mouse embryos.

FGFR1 FGFR3 FGFR4

3.06e-07511039771645
Pubmed

Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands.

FGFR1 FGFR3 FGFR4

3.06e-07511039013630
Pubmed

The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein.

FGFR1 FGFR3 FGFR4

3.06e-075110311566361
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA4B ERBB2 ABCA2 RASA3 VPS39 KHNYN EXTL3 FAT1 MROH1 ZBED4 PLEKHM2 ULK4 FGFR1 HERC2 MYRF ARHGAP21

4.11e-0711051101635748872
Pubmed

Phospholipase C-gamma as a signal-transducing element.

KL FGFR1 FGFR3 FGFR4

5.44e-0721110410579907
Pubmed

Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault.

FGFR1 FGFR3 FGFR4

6.11e-076110310572038
Pubmed

FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.

FGFR1 FGFR3 FGFR4

6.11e-076110319515808
Pubmed

Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1.

FGFR1 FGFR3 FGFR4

6.11e-076110324026051
Pubmed

FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells.

FGFR1 FGFR3 FGFR4

6.11e-07611039010207
Pubmed

Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domains.

FGFR1 FGFR3 FGFR4

6.11e-076110316365308
Pubmed

Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum.

FGFR1 FGFR3 FGFR4

6.11e-076110319232523
Pubmed

Differential expression of receptor tyrosine kinases (RTKs) and IGF-I pathway activation in human uterine leiomyomas.

ERBB2 FGFR1 FGFR3

6.11e-076110318231572
Pubmed

FGF signaling expands embryonic cortical surface area by regulating Notch-dependent neurogenesis.

FGFR1 FGFR3 NEUROG2 CUX1

6.63e-0722110422031906
Pubmed

Expression patterns of FGF receptors in the developing mammalian cochlea.

FGFR1 FGFR3 FGFR4

1.07e-067110320131355
Pubmed

FGF as a target-derived chemoattractant for developing motor axons genetically programmed by the LIM code.

FGFR1 FGFR3 FGFR4

1.07e-067110316772167
Pubmed

Activin and basic fibroblast growth factor regulate neurogenesis of murine embryonal carcinoma cells.

FGFR1 FGFR3 FGFR4

1.07e-06711038959336
Pubmed

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c.

FGFR1 FGFR3 FGFR4

1.70e-068110318187602
Pubmed

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.

FGFR1 FGFR3 FGFR4

1.70e-068110317623664
Pubmed

ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner.

ERBB2 FGFR3 FGFR4

1.70e-068110311940572
Pubmed

Syndecan-4 dependent FGF stimulation of mouse vibrissae growth.

FGFR1 FGFR3 FGFR4

1.70e-068110316989989
Pubmed

FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system.

KL FGFR1 FGFR3 FGFR4

2.12e-0629110421876757
Pubmed

NPAS1 represses the generation of specific subtypes of cortical interneurons.

RELN FGFR1 FGFR3 CUX1

2.12e-0629110425467980
Pubmed

Expression of Fgf receptors 1, 2, and 3 in the developing mid- and hindbrain of the mouse.

FGFR1 FGFR3 FGFR4

2.55e-069110315830353
Pubmed

Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development.

FGFR1 FGFR3 FGFR4

2.55e-069110331613912
Pubmed

Integration of FGF and TWIST in calvarial bone and suture development.

FGFR1 FGFR3 FGFR4

2.55e-069110310751173
Pubmed

The expression of fibroblast growth factors and their receptors in the embryonic and neonatal mouse inner ear.

FGFR1 FGFR3 FGFR4

2.55e-069110311335076
Pubmed

Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination.

FGFR1 FGFR3 FGFR4

2.55e-069110315229180
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

SEMA4B RELN PTPRU FGFR1 FGFR3 CUX1

3.16e-06126110616284245
Pubmed

Members of the Plag gene family are expressed in complementary and overlapping regions in the developing murine nervous system.

RELN NEUROG2 NEUROG3

3.63e-0610110316193498
Pubmed

Laminar patterning in the developing neocortex by temporally coordinated fibroblast growth factor signaling.

FGFR1 FGFR3 FGFR4

3.63e-0610110315470137
Pubmed

Regulation of external genitalia development by concerted actions of FGF ligands and FGF receptors.

FGFR1 FGFR3 FGFR4

3.63e-0610110315340846
Pubmed

The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence.

RELN NRP2 NEUROG2 CUX1

4.60e-0635110420943929
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

RELN COL12A1 FGFR1 FGFR3 FGFR4 NEUROG2 NEUROG3

4.98e-06210110716537572
Pubmed

Fgf20 is required for sensory epithelial specification in the developing cochlea.

FGFR1 FGFR3 FGFR4

4.99e-0611110318524904
Pubmed

Nervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain.

RELN CUX1 CNTN2

4.99e-0611110320170731
Pubmed

Fibroblast growth factor signalling in the hair growth cycle: expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle.

FGFR1 FGFR3 FGFR4

4.99e-061111038901049
Pubmed

Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens.

FGFR1 FGFR3 FGFR4

4.99e-0611110326906157
Pubmed

The murine gene, Traube, is essential for the growth of preimplantation embryos.

FGFR1 FGFR3 FGFR4

4.99e-0611110311071758
Pubmed

Immunohistochemical study of genesis of the mouse oral vestibule.

FGFR1 FGFR3 FGFR4

6.63e-0612110314964469
Pubmed

Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures.

FGFR1 FGFR3 FGFR4

6.63e-0612110310751172
Pubmed

Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4.

FGFR1 FGFR3 FGFR4

6.63e-0612110310918587
Pubmed

Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling.

FGFR1 FGFR3 FGFR4

6.63e-0612110312460940
Pubmed

The roles of FGF signaling in germ cell migration in the mouse.

FGFR1 FGFR3 FGFR4

6.63e-0612110316291796
Pubmed

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.

ERBB2 FGFR1 FGFR3 FGFR4

7.93e-0640110430898150
Pubmed

Testis Determination Requires a Specific FGFR2 Isoform to Repress FOXL2.

FGFR1 FGFR3 FGFR4

8.60e-0613110328938467
Pubmed

A quantitative method for evaluation of FGF family and FGF receptor family gene expression by RT-PCR.

FGFR1 FGFR3 FGFR4

8.60e-061311039385055
Pubmed

A point mutation in Fgf9 impedes joint interzone formation leading to multiple synostoses syndrome.

FGFR1 FGFR3 FGFR4

8.60e-0613110328169396
Pubmed

Expression of the fibroblast growth factor family and their receptor family genes during mouse brain development.

FGFR1 FGFR3 FGFR4

8.60e-061311038883961
Pubmed

Receptor specificity of the fibroblast growth factor family.

FGFR1 FGFR3 FGFR4

8.60e-061311038663044
Pubmed

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators.

RELN WWC2 STEAP1B STEAP1

9.66e-0642110423863479
Pubmed

Molecular cloning and characterization of a novel human Rab ( Rab2B) gene.

RAB2B RAB2A

9.91e-062110212376746
Pubmed

Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling.

FGFR1 FGFR3

9.91e-062110221779335
Pubmed

Fibroblast growth factor receptor 1 and 3 expression is associated with regulatory PI3K/AKT kinase activity, as well as invasion and prognosis, in human laryngeal cancer.

FGFR1 FGFR3

9.91e-062110229299828
Pubmed

siRNA mediated knockdown of fibroblast growth factor receptors 1 or 3 inhibits FGF-induced anchorage-independent clonogenicity but does not affect MAPK activation.

FGFR1 FGFR3

9.91e-062110216685373
Pubmed

Involvement of alpha-klotho and fibroblast growth factor receptor in the development of secondary hyperparathyroidism.

KL FGFR1

9.91e-062110220068287
Pubmed

Molecular analysis of 23 Pakistani families with autosomal recessive primary microcephaly using targeted next-generation sequencing.

ASPM WDR62

9.91e-062110227784895
Pubmed

Oncogene mutation profiling reveals poor prognosis associated with FGFR1/3 mutation in liposarcoma.

FGFR1 FGFR3

9.91e-062110227237367
Pubmed

Ligand specificity and heparin dependence of fibroblast growth factor receptors 1 and 3.

FGFR1 FGFR3

9.91e-06211021379594
Pubmed

FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung.

FGFR3 FGFR4

9.91e-06211029716527
Pubmed

Fibroblast growth factor receptors control epithelial-mesenchymal interactions necessary for alveolar elastogenesis.

FGFR3 FGFR4

9.91e-062110220093646
Pubmed

FGFR4 does not contribute to progression of chronic kidney disease.

KL FGFR4

9.91e-062110231575945
Pubmed

Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy.

RAB2B RAB2A

9.91e-062110228063257
Pubmed

Altered expressions of fibroblast growth factor receptors and alveolarization in neonatal mice exposed to 85% oxygen.

FGFR3 FGFR4

9.91e-062110217957151
Pubmed

Role of FGF Receptors and Their Pathways in Adrenocortical Tumors and Possible Therapeutic Implications.

FGFR1 FGFR4

9.91e-062110234956100
Pubmed

Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains.

FGFR1 FGFR3

9.91e-062110211585811
Pubmed

Genome-wide copy number aberrations and HER2 and FGFR1 alterations in primary breast cancer by molecular inversion probe microarray.

ERBB2 FGFR1

9.91e-062110228125801
Pubmed

Parathyroid Klotho and FGF-receptor 1 expression decline with renal function in hyperparathyroid patients with chronic kidney disease and kidney transplant recipients.

KL FGFR1

9.91e-062110220686451
Pubmed

Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis.

FGFR1 FGFR4

9.91e-062110218480409
Pubmed

RAS-MAPK Reactivation Facilitates Acquired Resistance in FGFR1-Amplified Lung Cancer and Underlies a Rationale for Upfront FGFR-MEK Blockade.

FGFR1 FGFR3

9.91e-062110229654068
Pubmed

CD98 regulates the phosphorylation of HER2 and a bispecific anti-HER2/CD98 antibody inhibits the growth signal of human breast cancer cells.

ERBB2 SLC3A2

9.91e-062110236811310
Pubmed

FGFR4 and Klotho Polymorphisms Are Not Associated with Cardiovascular Outcomes in Chronic Kidney Disease.

KL FGFR4

9.91e-062110234673637
Pubmed

Fibroblast growth factor receptor-1 protein expression is associated with prognosis in estrogen receptor-positive/human epidermal growth factor receptor-2-negative primary breast cancer.

ERBB2 FGFR1

9.91e-062110226801869
Pubmed

Inhibition of STEAP1 ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells.

STEAP1B STEAP1

9.91e-062110237209327
Pubmed

Fibroblast growth factor receptors-1 and -3 play distinct roles in the regulation of bladder cancer growth and metastasis: implications for therapeutic targeting.

FGFR1 FGFR3

9.91e-062110223468956
Pubmed

Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients.

KL FGFR1

9.91e-062110219890272
InteractionFGF23 interactions

KL FGFR1 FGFR3 FGFR4

5.17e-0881074int:FGF23
InteractionKLB interactions

KL FGFR1 FGFR3 FGFR4

3.60e-07121074int:KLB
InteractionKL interactions

KL FGFR1 FGFR3 FGFR4

7.22e-07141074int:KL
InteractionGRAMD2B interactions

GOLM2 GRAMD1A SEC22A MYRF GRAMD1C

2.79e-06421075int:GRAMD2B
InteractionFGF6 interactions

FGFR1 FGFR3 FGFR4

5.01e-0671073int:FGF6
InteractionFGF18 interactions

FGFR1 FGFR3 FGFR4

5.01e-0671073int:FGF18
InteractionFGF5 interactions

FGFR1 FGFR3 FGFR4

7.99e-0681073int:FGF5
InteractionFGF7 interactions

FGFR1 FGFR3 FGFR4

7.75e-05161073int:FGF7
InteractionFGF9 interactions

FGFR1 FGFR3 FGFR4

7.75e-05161073int:FGF9
InteractionGARIN4 interactions

RAB2B RAB2A

8.35e-0531072int:GARIN4
InteractionFGF17 interactions

DDX31 FGFR1 FGFR3 FGFR4

8.66e-05441074int:FGF17
GeneFamilyC2 and WW domain containing

WWP2 WWC2

1.15e-044802838
GeneFamilyProteases, serine|STEAP family

STEAP1B STEAP1

1.92e-0458021324
GeneFamilyReceptor Tyrosine Kinases|CD molecules

FGFR1 FGFR3 FGFR4

7.32e-0440803321
GeneFamilyBlood group antigens|XK related family

XKR9 XKR4

1.04e-0311802955
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

GRAMD1A GRAMD1C

1.46e-03138021146
GeneFamilySNAREs|BCL2 homology region 3 (BH3) only

SEC22A SEC22C

1.96e-03158021124
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASA3 RALGPS2 PLEKHH1 PLEKHM2 ARHGAP21

2.20e-03206805682
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRU PTPRN2

3.84e-0321802813
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

FGFR1 FGFR3 FGFR4 CNTN2

5.67e-03161804593
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HOMTN

RELN TMEM169 GRIA4 XKR4 NRP2 TENM3 TRPV2 BRINP2 SV2C PIP4P2 CNTN2

7.66e-0738911011M39073
CoexpressionPEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_6

KMO FAM83B BRINP2 UGT2B28

6.43e-06291104M2412
CoexpressionGSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_DN

GRAMD1A EXTL3 ZDHHC12 RAB2A NEUROG3 STEAP1 BRWD1

2.22e-052001107M4108
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

SEMA4B PRTN3 DNAH10 RALGPS2 NXPE3 SCD ASPM

3.81e-071841107c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

SEMA4B PRTN3 DNAH10 RALGPS2 NXPE3 SCD ASPM

3.81e-0718411072fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA2 NXPE3 PLEKHH1 SCD MYRF ARHGAP21 CNTN2

5.44e-071941107cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell(3)_Chondrocytes-(30)_Chondro|World / Cell class and subclass of bone marrow stroma cells in homeostatis

PAPPA2 COL12A1 GOLM2 WWP2 TENM3 FGFR1 FGFR3

6.03e-071971107a07ab2564ca7d577fd47f444dd7b0c25556e9fc4
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

RELN TSPEAR NRP2 TENM3 HECW2 SNTG2

5.37e-061781106c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN CETP NRP2 SCD SNTG2 FUT7

5.54e-0617911061c0c0647a111f691dae55f4ed8c51006059ce020
ToppCellwk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PAPPA2 COL12A1 WWP2 TENM3 FGFR1 STEAP1

6.10e-0618211060e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA4B PRTN3 DNAH10 NXPE3 SCD ASPM

6.49e-061841106a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA4B PRTN3 DNAH10 NXPE3 SCD ASPM

6.49e-061841106081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

SEMA4B PRTN3 DNAH10 NXPE3 SCD ASPM

6.49e-06184110645f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SEMA4B PRTN3 DNAH10 NXPE3 SCD ASPM

6.49e-06184110684c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SEMA4B PRTN3 DNAH10 NXPE3 SCD ASPM

6.49e-061841106d31d4116d1d196633784863781fa45673607a421
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B RALGPS2 KMO SCD PLCG2 BRWD1

7.12e-061871106b51af2824e65734f333b1325117f4a2e88b17c23
ToppCellfacs-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B RALGPS2 KMO SCD PLCG2 BRWD1

7.12e-0618711063ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA2 PLEKHH1 SCD MYRF ARHGAP21 CNTN2

8.53e-061931106947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCellNS-critical-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERBB2 FER1L6 PLEKHH1 FGFR3 MYRF STEAP1

8.78e-0619411062172d951896265243d14996eacce5aab5e14e26e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA2 NRP2 SCD MYRF ARHGAP21 CNTN2

9.04e-0619511061e28617ca55e5f318a228357737b968dfac8cca0
ToppCellTracheal-10x5prime-Stromal-Schwann|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RELN ABCA2 XKR4 SCD SV2C CNTN2

9.31e-061961106b6226163d9fc93ecfff2115bb74408303a000490
ToppCellfacs-Brain_Non-Myeloid-Cortex|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA2 PPP1R3G PLEKHH1 FGFR3 MYRF CNTN2

9.31e-061961106256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 FAT1 TENM3 BRINP2 FGFR1 FGFR3

9.58e-0619711062ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA2 PLEKHH1 SCD MYRF ARHGAP21 CNTN2

9.58e-06197110682b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellMacroglial-Oligodendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABCA2 PLEKHH1 SCD HECW2 MYRF CNTN2

1.04e-0520011064dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA2 PLEKHH1 SCD MYRF ARHGAP21 CNTN2

1.04e-052001106acdef0b9096c774040948fc75621ff2b08ea2ee8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA2 PLEKHH1 SCD MYRF ARHGAP21 CNTN2

1.04e-052001106091a18d6efed81cab99955c3047f172170f70476
ToppCellMacroglial-Oligodendrocytes-OPALIN--|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABCA2 PLEKHH1 SCD HECW2 MYRF CNTN2

1.04e-05200110626b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA2 PLEKHH1 SCD MYRF ARHGAP21 CNTN2

1.04e-0520011063b8513defe25262ab4b492345b2628570eaefd17
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Macroglial-Glia_progenitor_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

CATSPERE PRTN3 DDX31 WDR91 PLCG2 MYRF

1.04e-0520011060b91c8da21ba488109f15c9b927c1dcaf8c6b0ae
ToppCellMacroglial-Oligodendrocytes-OPALIN---|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABCA2 PLEKHH1 SCD HECW2 MYRF CNTN2

1.04e-0520011061314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCellMacroglial-Oligodendrocytes-OPALIN-|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABCA2 PLEKHH1 SCD HECW2 MYRF CNTN2

1.04e-0520011068b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCellMacroglial-Oligodendrocytes-OPALIN----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABCA2 PLEKHH1 SCD HECW2 MYRF CNTN2

1.04e-052001106272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCellMacroglial-Oligodendrocytes-OPALIN|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABCA2 PLEKHH1 SCD HECW2 MYRF CNTN2

1.04e-0520011065f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_ALM_Olfr111_Spon1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PAPPA2 COL12A1 NRP2 ZDHHC12 SCN10A

1.60e-051271105cd69ba386796715e87674f8324d2acaad1d4d094
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 FAM83B ASPM SNTG2 WDR62

1.93e-05132110502491930097b75aaeedab9e8200711b0dc610944
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B PPP1R3G TENM3 FGFR3 STAG3

4.03e-0515411055ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCellControl-Endothelial-Epi-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 WDR91 SEC22C MROH1 PTPRN2

4.42e-0515711054d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCellControl-Endothelial-Epi-like-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 WDR91 SEC22C MROH1 PTPRN2

4.42e-0515711052c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_naive|lymph-node_spleen / Manually curated celltypes from each tissue

RALGPS2 PPP1R3G KMO STEAP1B STAG3

4.56e-0515811057098847804dd90fa1dd74536e4e90f989b630fe4
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 DNAH10 KL SCN10A SNTG2

4.56e-051581105f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 DNAH10 KL SCN10A SNTG2

4.56e-0515811058c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN TSPEAR NRP2 HECW2 SNTG2

4.98e-051611105fb59d96c2aa9e4654f02bf6ce36bf832776cb4dd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN TSPEAR NRP2 HECW2 SNTG2

4.98e-051611105c53c461fc721a7960cef86662f49e2a495520701
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN TSPEAR NRP2 HECW2 SNTG2

5.13e-0516211052ac02523348660e514d464f8f2434ee0c312d784
ToppCellHealthy_Control-Lymphoid-B-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

RALGPS2 PLEKHH1 PTPRN2 FUT7 GRAMD1C

5.29e-051631105d84bd41b4494c7d5c7f88d511bfe481fb12f079d
ToppCellControl-APC-like-Monocytes|Control / group, cell type (main and fine annotations)

DDX60 KMO SLC35F2 STEAP1B PIP4P2

5.29e-0516311054bc80a2c741d462724b6f3902377d48c57478932
ToppCellHealthy_Control-Lymphoid-B|Healthy_Control / Condition, Lineage, Cell class and cell subclass

RALGPS2 PLEKHH1 PTPRN2 FUT7 GRAMD1C

5.29e-0516311050f723ec2503afa1b3ebb0754972438ffb6e6179d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RELN TSPEAR NRP2 HECW2 SNTG2

5.44e-051641105a784f47f67a5eda84d58ad7d9400e3978edbb487
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RELN TSPEAR NRP2 HECW2 SNTG2

5.44e-0516411051a1795969673232191425dde84ab24ee6a98143f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RELN TSPEAR NRP2 HECW2 SNTG2

5.44e-0516411058f074940afdbda88a4b697a7ddc687e09a4b818b
ToppCellAdult-Epithelial-lung_goblet_cell-D175|Adult / Lineage, Cell type, age group and donor

FER1L6 NWD2 PTPRN2 PDE8B STEAP1

5.44e-0516411056e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

RELN NRP2 HECW2 SNTG2 STEAP1B

5.93e-05167110597d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCellmild-Lymphocytic-B_cells_2|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SEMA4B RALGPS2 KMO PLCG2 STAG3

5.93e-0516711050811f7559c2a7151693771e52e14af3978997118
ToppCellCOVID-19-Heart-Adipocyte|Heart / Disease (COVID-19 only), tissue and cell type

NWD2 TENM3 SCD FGFR4 STEAP1

6.27e-051691105bd39f85b48207955f80ca120a11e15a0124117b9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN TSPEAR NRP2 HECW2 SNTG2

6.45e-0517011056035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN TSPEAR NRP2 HECW2 SNTG2

6.45e-051701105c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN TSPEAR NRP2 HECW2 SNTG2

6.45e-051701105dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN TSPEAR NRP2 SV2C SNTG2

6.45e-0517011054848965bc7e9356c6601bb41eeea1553d2eea87e
ToppCellCD8+_Memory_T_cell-FLU-3|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

TRPC1 RALGPS2 SCD GRAMD1C WDR62

6.82e-05172110545ac433dbb3796f69e886c04457b2971403050ee
ToppCelldroplet-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 KMO NXPE3 SCD BRWD1

7.01e-05173110525d72fa7a84baf5660ead6da67327590f5c91860
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

FAT1 TENM3 ASPM FGFR1 FGFR3

7.20e-051741105fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USP30 SEMA4B RALGPS2 WDR91 FUT7

7.40e-05175110587e557f7508c88b2087db5d57e77d5e2c92ca083
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

RELN TSPEAR NRP2 HECW2 SNTG2

7.60e-05176110598c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

RELN TSPEAR NRP2 HECW2 SNTG2

7.60e-051761105c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellwk_08-11-Mesenchymal-Chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PAPPA2 COL12A1 WWP2 TENM3 STEAP1

7.60e-0517611051af28b701c4598ce761f85adbd5d79e4918d265a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN TSPEAR NRP2 HECW2 SNTG2

7.81e-051771105c274fbdc141855ff4581d437d4997c64cc193278
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RRM1 NXPE3 TRPV2 FUT7 WDR62

7.81e-051771105f10f77130dbb2c0ad1b436ceb4fb1deac2b0267c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN TSPEAR NRP2 HECW2 SNTG2

7.81e-051771105f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RRM1 SLC25A32 SLC35F2 FUT7 WDR62

7.81e-0517711051d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCellCOVID-19-Heart-Lymph_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

RELN TSPEAR NRP2 HECW2 SNTG2

7.81e-051771105326fde0734ef0d7272693966d346ca479b9d8147
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN TSPEAR NRP2 HECW2 SNTG2

7.81e-051771105c8a51e480b978dc0ded85583261f2c892e085be8
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX31 TRPC1 RALGPS2 NXPE3 FGFR1

8.23e-051791105025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERBB2 FER1L6 PLEKHH1 PLCG2 ARHGAP21

8.23e-0517911056e965e424eebef50f0202cff75f458be395cfca1
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RRM1 CD1D PIK3CG PIP4P2 WDR62

8.23e-05179110506d412fc096d88de168969466ce422f0ab5553b2
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN CETP TSPEAR NRP2 FUT7

8.23e-051791105dfd5b25f2a6a5a8bf4714f1516cb0997de72b06f
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN RRM1 NRP2 TENM3 WDR62

8.23e-051791105df4d0b2fe47d2c7def729b3217cb01ced01495ff
ToppCellCOVID-19_Moderate-B_intermediate|World / disease group, cell group and cell class

SEMA4B RALGPS2 KMO PLCG2 STEAP1B

8.45e-051801105bd81b87a6dc81e5ab4a6c948eb0c80f14401a6a7
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

VPS13C BRINP1 NRP2 FGFR3 FGFR4

8.45e-051801105adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCellfacs-Kidney-nan-24m-Mesenchymal-kidney_interstitial_fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRTN3 MMP23B FGFR1 FUT7 WDR62

8.67e-051811105c7f5aedcb74c21fb587a95a16d700e2a38a380ee
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA4B RALGPS2 KMO STEAP1B STAG3

8.67e-0518111056df40f86c569b6ecfc3137a68d1355b012dbf6bf
ToppCellfacs-Kidney-nan-24m-Mesenchymal-kidney_interstitial_fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRTN3 MMP23B FGFR1 FUT7 WDR62

8.67e-0518111050ec9621a078d004bbd25a587757d24b5cf162959
ToppCellfacs-Skin-Telogen-3m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM83B PPP2R5A SCD EPHX3 CUX1

9.13e-051831105ed1e0b07475f9951728682ed70b85367cf2a744d
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

PPP2R5A NWD2 TENM3 PDE8B SCD

9.13e-0518311053f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCA2 PLEKHH1 SCD MYRF CNTN2

9.13e-05183110593213124e55d1b673dd345188caf8b5bd31d99fe
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ERBB2 COL12A1 MMP23B WWC2 MYRF

9.13e-0518311056821dca076318115d360ff426eb1218cfe104063
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCA2 PLEKHH1 SCD MYRF CNTN2

9.37e-051841105f6d6b3ddada66dae28d3306415bf4efe0934208a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN COL12A1 DNAH10 FAT1 CNTN2

9.37e-0518411052cbed6462fea2622871bb7e49b0df3d984239281
ToppCellMesenchymal_cells-Chondrocytes|World / Lineage and Cell class

COL12A1 WWP2 FGFR3 PPP1R36 STEAP1

9.37e-0518411051e03f9f08de5ad4d45388a95afad9f23ff0d0e28
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN COL12A1 DNAH10 FAT1 CNTN2

9.37e-051841105ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN COL12A1 DNAH10 FAT1 CNTN2

9.37e-0518411052b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN CETP NRP2 SCD SNTG2

9.37e-0518411053b0389c3a5a16697de860e98ebc48ed39ede646f
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

SEMA4B XKR9 FER1L6 NOX1 PTPRN2

9.37e-051841105d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN XKR4 NRP2 FAT1 TENM3

9.61e-05185110534fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B RALGPS2 KMO SCD BRWD1

9.61e-051851105eb338fcda0b237c2e0b9b4b0daf51febbfe1d79c
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B RALGPS2 KMO SCD BRWD1

9.61e-051851105c31bb53852caf36964b83b28bcaee07b679da779
ToppCell18-Distal-Epithelial-Epithelial|Distal / Age, Tissue, Lineage and Cell class

RELN TMEM169 XKR4 NWD2 CNTN2

9.61e-051851105d2a266724f3f70f746a78034f308d98f8b7a66e3
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCA2 PLEKHH1 SCD MYRF CNTN2

9.61e-0518511051d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCA2 PLEKHH1 SCD MYRF CNTN2

9.61e-051851105b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN XKR4 NRP2 FAT1 TENM3

9.61e-0518511058816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MMP23B KMO KL FGFR4

9.84e-059711042cd5cafdf0a9a468baaafd4613d790fc048ee53e
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Coch_(Coch)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MMP23B KMO KL FGFR4

9.84e-05971104adda7a49b7754ed110e212346768bf52107c26fc
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Coch_(Coch)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MMP23B KMO KL FGFR4

9.84e-059711046d865ec3a413f595de17e0a5f8c61666ebb3e252
Drug3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)-phenylamino)pyrimidin-4-yl)-1-methylurea

FGFR1 FGFR3 FGFR4

4.37e-0741103ctd:C568950
DrugQuinethazone [73-49-4]; Up 200; 13.8uM; PC3; HT_HG-U133A

ABCA2 RALGPS2 KMO PPP2R5A SCN10A FGFR1 FGFR3 GRAMD1C WDR62

5.16e-0719811094529_UP
DrugPalifermin

FGFR1 FGFR3 FGFR4

2.17e-0661103DB00039
DrugFlucytosine [2022-85-7]; Down 200; 31uM; MCF7; HT_HG-U133A

ABCA2 KHNYN IBTK WWC2 FGFR4 RAB2A STAG3 BRWD1

4.52e-0619311085289_DN
DrugPhenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; PC3; HT_HG-U133A

EXTL3 KMO NRP2 NOX1 PDE8B SCN10A MYRF GRAMD1C

4.52e-0619311086699_DN
Drug(R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; HL60; HT_HG-U133A

RELN ABCA2 EXTL3 PTPRU NRP2 PDE8B SCN10A SV2C

5.45e-0619811082496_UP
Drugnitrobenzyl-DOTA

PTPRN2 FGFR1 FGFR3 FGFR4

2.41e-05351104CID000129949
Diseasebone disease (implicated_via_orthology)

FGFR1 FGFR3 FGFR4

4.61e-0751073DOID:0080001 (implicated_via_orthology)
Diseaseoral squamous cell carcinoma (is_implicated_in)

FAT1 BRINP2 FGFR3 FGFR4

3.13e-06281074DOID:0050866 (is_implicated_in)
Diseasevenous thromboembolism, von Willebrand factor measurement

DDX31 SLC44A2 PLCG2 MYRF

1.65e-05421074EFO_0004286, EFO_0004629
Diseasehigh grade glioma (implicated_via_orthology)

FGFR1 FGFR3 FGFR4 WDR62

1.98e-05441074DOID:3070 (implicated_via_orthology)
Diseaseosteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty

FGFR3 CUX1 BRWD1

5.88e-05211073EFO_0004616, EFO_0010726, EFO_1000786
DiseaseTWIST1-related craniosynostosis

FGFR1 FGFR3

7.78e-0541072cv:C4551902
Diseasestomach cancer (is_marker_for)

TRPC1 CD1D ASPM FGFR4 CUX1

1.72e-041421075DOID:10534 (is_marker_for)
DiseaseHead and Neck Neoplasms

ERBB2 FAT1 FGFR1

2.34e-04331073C0018671
DiseaseCraniosynostosis syndrome

FGFR1 FGFR3

2.70e-0471072cv:C0010278
Diseasevenous thromboembolism

PAPPA2 RELN SLC44A2 PPP1R3G SV2C PLCG2 FBXO15 BRWD1

2.78e-044601078EFO_0004286
Diseaseprotein FAM177A1 measurement

CETP SLC44A2

3.60e-0481072EFO_0801948
Diseasecirculating alpha-Klotho measurement

KL FGFR1

3.60e-0481072EFO_0020102
Diseasekynurenine measurement

KMO PLEKHH1 BRWD1

3.85e-04391073EFO_0008529
DiseaseNeoplasm of uncertain or unknown behavior of breast

ERBB2 FGFR1 HERC2

4.47e-04411073C0496956
DiseaseBreast adenocarcinoma

ERBB2 FGFR1 HERC2

4.47e-04411073C0858252
DiseaseMalignant Head and Neck Neoplasm

ERBB2 FAT1 FGFR1

5.51e-04441073C0278996
DiseaseAsthma, Occupational

TENM3 HERC2

5.75e-04101072C0264423
Diseaselevel of Phosphatidylcholine (O-18:2_16:0) in blood serum

CETP MYRF

5.75e-04101072OBA_2045132
DiseaseHead and Neck Carcinoma

ERBB2 FGFR1

5.75e-04101072C3887461
Diseaseglucagon-like peptide-1 measurement

COL12A1 ULK4

5.75e-04101072EFO_0008465
DiseasePathological accumulation of air in tissues

KL PPP2R5A

8.40e-04121072C0013990
Diseasemood disorder

RELN SV2C

9.90e-04131072EFO_0004247
DiseaseCarcinogenesis

ERBB2 CUX1

9.90e-04131072C0596263
DiseaseAutosomal recessive primary microcephaly

ASPM WDR62

1.33e-03151072cv:C3711387
Diseaselevel of Phosphatidylcholine (O-18:1_20:4) in blood serum

CETP MYRF

1.33e-03151072OBA_2045131
Diseaselysophosphatidylcholine measurement

CETP SCD MYRF

1.50e-03621073EFO_0010224
Diseasegliosarcoma

FGFR1 FGFR3

1.51e-03161072C0206726
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

ASPM WDR62

1.51e-03161072DOID:0070296 (is_implicated_in)
Diseasewaist-hip ratio

PAPPA2 XKR9 DNAH10 WWP2 ZDHHC12 PPP2R5A PDE8B FGFR1 FGFR4 ARHGAP21 CUX1 CNTN2

1.64e-03122610712EFO_0004343
DiseaseFEV/FEC ratio

XKR9 VPS13C BRINP1 FAM83B NRP2 WWC2 ULK4 FGFR1 FGFR3 FGFR4 CUX1 CNTN2

1.66e-03122810712EFO_0004713
Diseaselung non-small cell carcinoma (is_implicated_in)

SLC3A2 FAT1 FGFR1 FGFR4

1.67e-031391074DOID:3908 (is_implicated_in)
DiseaseBrachycephaly

FGFR1 FGFR3

1.71e-03171072C0221356
Diseasestem Cell Factor measurement

CETP PLCG2 MYRF

1.88e-03671073EFO_0008291
Diseaseesterified cholesterol measurement, high density lipoprotein cholesterol measurement

CETP MYRF

2.14e-03191072EFO_0004612, EFO_0008589
Diseasevenous thromboembolism, plasminogen activator inhibitor 1 measurement

SLC44A2 PLCG2

2.62e-03211072EFO_0004286, EFO_0004792
Diseaselevel of Phosphatidylcholine (16:1_18:2) in blood serum

CETP MYRF

2.62e-03211072OBA_2045083
DiseaseAutosomal Recessive Primary Microcephaly

ASPM WDR62

2.87e-03221072C3711387
DiseasePrimary microcephaly

ASPM WDR62

2.87e-03221072C0431350
Diseasevenous thromboembolism, tissue plasminogen activator measurement

SLC44A2 PLCG2

3.14e-03231072EFO_0004286, EFO_0004791
Diseaselung non-small cell carcinoma (is_marker_for)

RRM1 SLC3A2 FGFR4 CUX1

3.39e-031691074DOID:3908 (is_marker_for)
DiseaseNeoplasm of the genitourinary tract

ERBB2 FGFR3

3.41e-03241072cv:C0042065
Diseasestomach carcinoma (is_marker_for)

ERBB2 SLC3A2

3.41e-03241072DOID:5517 (is_marker_for)
DiseaseGiant Cell Glioblastoma

FAT1 FGFR1 FGFR3

3.57e-03841073C0334588

Protein segments in the cluster

PeptideGeneStartEntry
VERTSYNGHLTIWFT

C21orf62

71

Q9NYP8
RRRFTHQSDVWSYGV

ERBB2

896

P04626
FYSNIFRWETTISIA

GRAMD1C

111

Q8IYS0
RMLYFWFSERVFHSL

CETP

276

P11597
HLWTNYTTRAFIFLS

CATSPERE

531

Q5SY80
NRWKTFFETVHIYLR

BRINP1

606

O60477
TIGSIFFTWRLYNER

BTN1A1

261

Q13410
STVINWFHNYRSRIR

CUX1

1286

P39880
LFDRVYTHQSDVWSF

FGFR4

661

P22455
RAAITLQHYFRTWQT

ASPM

2861

Q8IZT6
YRLWSLERTAHTFES

GRAMD1A

631

Q96CP6
QYVWHTSSGENLFRI

NWD2

1381

Q9ULI1
YDITRRDTFNHLTTW

RAB2A

86

P61019
YDITRRETFNHLTSW

RAB2B

86

Q8WUD1
RWFRLTNHEFTYHKS

RASA3

601

Q14644
RTVTQFHFLSWYDRG

PTPRN2

901

Q92932
SSAWSTVFRHVRYEN

SLC25A32

11

Q9H2D1
GRIFYVDHVNRTTTW

HECW2

821

Q9P2P5
SATEFIRRSYFEVFW

NOX1

191

Q9Y5S8
RLDRESTSHYWLTVF

FAT1

1096

Q14517
VVAFDVYNHRWRSLT

KLHL34

336

Q8N239
IETLRFAHNYIWALT

NEUROG2

151

Q9H2A3
FAHNYIWALTETLRL

NEUROG2

156

Q9H2A3
RFAHNYIWALTQTLR

NEUROG3

126

Q9Y4Z2
ASTSWRHFAEVAYIV

HERC2

1111

O95714
AGRFHTVLWTREAVY

IBTK

291

Q9P2D0
LLNENFRREYWTIFH

GPR50

296

Q13585
CEYFILRNIHTFEFW

DDX60

351

Q8IY21
HTTKSFLRNWRIESY

FAM83B

486

Q5T0W9
VLFLVSRFSPYEWHT

GRIA4

561

P48058
TLRAWFQVIEANYHS

PDE8B

596

O95263
IFNWVLSYRRDSDIF

FUT7

136

Q11130
LTWVFLALYFSRHQV

NRP2

6

O60462
NDYTLSFWRSGRVQH

PLCG2

571

P16885
DFFTRVALYVDWIRS

PRTN3

231

P24158
VFEDYVHSSERRVSW

DDX31

696

Q9H8H2
FSAYDVLFHQWLQSR

MROH1

221

Q8NDA8
SIYHASEFTQWRRVI

RELN

981

P78509
VRHFQFLRWSAYRDT

PTPRU

1336

Q92729
EAFSRYNISWQLSVH

PAPPA2

556

Q9BXP8
VTFSRIRYHEAVQRW

KMO

401

O15229
NIHISDEWYTRFRVS

COL12A1

2121

Q99715
WETLQHIFRVYRSSF

CD1D

81

P15813
ALFDRIYTHQSDVWS

FGFR1

671

P11362
SRRFYHLANDNFIWI

FBXO15

101

Q8NCQ5
RNFTLTVTDFYRSWN

EXTL3

591

O43909
SVFRTVHTQGQWAYR

DLGAP3

726

O95886
FDRLTVEEHLWFYSR

ABCA2

1076

Q9BZC7
FSYIRHWDQNERFLV

SLC3A2

551

P08195
YLLSFRRQGSTHWQT

CNTN2

746

Q02246
VWEVRYIEHNARTFN

BRWD1

1226

Q9NSI6
FSWRYQLREFQSRFH

EPHX3

111

Q9H6B9
ELGVTHYRFSISWAR

KL

141

Q9UEF7
VQYFWDRGHRDITVF

KHNYN

466

O15037
FQTDFRVYLHLRQTW

SLC44A2

301

Q8IWA5
LFDRVYTHQSDVWSF

FGFR3

666

P22607
AIYWERSLFFRIKHT

DNAH10

571

Q8IVF4
YELRNLWQLFFHVTV

SEC22A

271

Q96IW7
STDFYHTQDFLEWRR

SEC22C

21

Q9BRL7
VAFTRRFNHVSFWVV

RALGPS2

91

Q86X27
SSGYWVLVVHFTRRE

PLEKHM2

61

Q8IWE5
VYFISSWGDQTFRLH

FER1L6

581

Q2WGJ9
VVLAFNYWSISSRHV

GOLM2

26

Q6P4E1
RITAYNVWAVINHFS

TAS2R46

81

P59540
GSAYQFHSWRVFVIV

SV2C

311

Q496J9
VHLFGDSTIRQWFEY

NXPE3

356

Q969Y0
LRWDHFNLTYRILSF

MMP23B

86

O75900
YDSVFSVVRRHQFRW

CMAS

166

Q8NFW8
FARRFRATYVSWAIA

PIP4P2

216

Q8N4L2
RDTLFYGVFTSQWHR

SEMA4B

336

Q9NPR2
FLSVHSSYQWELRLT

OCSTAMP

371

Q9BR26
RAVTVRYTFTEWRSF

PPP1R3G

246

B7ZBB8
VSTFDWVRAERTYHL

SNTG2

336

Q9NY99
LSWFILHARYRVIHF

SLC35F2

151

Q8IXU6
VSDSLTWREFHYIQS

STEAP1

241

Q9UHE8
SVSDSLTWREFHYIQ

STEAP1B

221

Q6NZ63
LGNRWKTFFETVHVY

BRINP2

631

Q9C0B6
SSSHFQVAERALYFW

PPP2R5A

361

Q15172
SWLFARVTETVHTSY

C15orf61

126

A6NNL5
FWFLRSEIAQSRHYQ

PIK3CG

696

P48736
WYIFSLAHVAIFVTR

TRPC1

596

P48995
FWLHTSFIENNRLYL

TPTE

496

P56180
FYYVDHNTRTTTWQR

WWP2

346

O00308
VFYIDHNTRRTSWID

WWC2

26

Q6AWC2
LSAFYNTHDLTRWEL

STAG3

706

Q9UJ98
AIETYNLLSERWFTH

RRM1

186

P23921
YRIVEHSWFESFIIF

SCN10A

1146

Q9Y5Y9
RRHVFIWISFIDSYF

TRPV2

456

Q9Y5S1
SLSVQVFSFRWFVHD

XKR4

156

Q5GH76
VFERSPFLTQYHTVW

TENM3

916

Q9P273
QLIWSVVRHYSEQFL

VPS13C

3396

Q709C8
TFCTYVAWIVFRRQH

PPP1R36

241

Q96LQ0
SEYRWHINFTTFFID

SCD

311

O00767
HQFSSWESRIYAVAT

PLEKHH1

416

Q9ULM0
QSVDLIFTRLWIYSH

RWDD2B

181

P57060
LDRALYWHFLTDTFT

TPGS2

176

Q68CL5
SYFVTVGNRHVRFWF

WDR62

211

O43379
AFIRWLEEFTSQYSR

USP30

91

Q70CQ3
FDGRTFSVNSIIYRW

TSPEAR

606

Q8WU66
LRVAARDLTWFQYHS

UGT2B28

476

Q9BY64
TWEFISSHRIAYLRQ

ZDHHC12

211

Q96GR4
FLVYNEERTFWHKIS

TMEM169

191

Q96HH4
VSFSNHRTRSWDYIE

ARHGAP21

486

Q5T5U3
YFSRQWADTFIVSLH

WDR91

146

A4D1P6
ITWERIISHFDIFAF

PTDSS1

156

P48651
EIVVNNRITWLFHYS

TDH

111

Q8IZJ6
ILWYLFRHSTADSLR

ULK4

651

Q96C45
LHLIFSYSVWVLRDF

VPS39

551

Q96JC1
IWVSVRFFHEGQYVF

XKR9

26

Q5GH70
REYLTLTAHWVSFES

ZBED4

741

O75132
VRLIQVYHISRNSWF

KLHL38

446

Q2WGJ6
WPITILSFREFTYHF

MYRF

1106

Q9Y2G1