Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	RRH OR2B11 OR5K3 OR5M10 GPR15 OR4D5 OR5V1 OR6N2 OR1J1 IL17RE DDR2 GABRA2 GABRA3 OR4C45	3.51e-07	1353	42	14	GO:0004888
GeneOntologyMolecularFunction	olfactory receptor activity	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	2.74e-06	431	42	8	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	RRH OR2B11 OR5K3 OR5M10 GPR15 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	1.11e-05	884	42	10	GO:0004930
GeneOntologyMolecularFunction	benzodiazepine receptor activity	GABRA2 GABRA3	2.35e-04	11	42	2	GO:0008503
GeneOntologyMolecularFunction	K63-linked deubiquitinase activity	USP9X STAMBP	5.09e-04	16	42	2	GO:0061578
GeneOntologyMolecularFunction	GABA-gated chloride ion channel activity	GABRA2 GABRA3	6.47e-04	18	42	2	GO:0022851
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH1 DNAH11	6.47e-04	18	42	2	GO:0008569
GeneOntologyMolecularFunction	GABA-A receptor activity	GABRA2 GABRA3	7.22e-04	19	42	2	GO:0004890
GeneOntologyMolecularFunction	GABA receptor activity	GABRA2 GABRA3	9.71e-04	22	42	2	GO:0016917
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GABRA2 GABRA3	1.16e-03	24	42	2	GO:0099507
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	CACNA1H NALCN	1.36e-03	26	42	2	GO:0005248
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH1 DNAH11	1.58e-03	28	42	2	GO:0051959
GeneOntologyMolecularFunction	odorant binding	OR5K3 OR5M10 OR6N2	2.41e-03	127	42	3	GO:0005549
GeneOntologyMolecularFunction	monoatomic ion channel activity	CACNA1H PIEZO2 NALCN GABRA2 GABRA3	2.65e-03	459	42	5	GO:0005216
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH1 DNAH11	2.75e-03	37	42	2	GO:0045505
GeneOntologyMolecularFunction	channel activity	CACNA1H PIEZO2 NALCN GABRA2 GABRA3	4.70e-03	525	42	5	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	CACNA1H PIEZO2 NALCN GABRA2 GABRA3	4.74e-03	526	42	5	GO:0022803
GeneOntologyMolecularFunction	ligand-gated monoatomic anion channel activity	GABRA2 GABRA3	4.96e-03	50	42	2	GO:0099095
GeneOntologyMolecularFunction	gated channel activity	CACNA1H PIEZO2 GABRA2 GABRA3	5.22e-03	334	42	4	GO:0022836
GeneOntologyMolecularFunction	sodium channel activity	CACNA1H NALCN	5.36e-03	52	42	2	GO:0005272
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GABRA2 GABRA3	6.41e-03	57	42	2	GO:1904315
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	GABRA2 GABRA3	7.08e-03	60	42	2	GO:0099529
GeneOntologyMolecularFunction	transmitter-gated channel activity	GABRA2 GABRA3	8.26e-03	65	42	2	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	GABRA2 GABRA3	8.26e-03	65	42	2	GO:0022824
GeneOntologyBiologicalProcess	detection of stimulus	RRH OR2B11 OR5K3 OR5M10 PIEZO2 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	1.09e-06	722	41	10	GO:0051606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR2B11 OR5K3 OR5M10 PIEZO2 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	1.67e-06	582	41	9	GO:0050906
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	1.81e-06	432	41	8	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	3.12e-06	465	41	8	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	4.26e-06	485	41	8	GO:0050907
GeneOntologyBiologicalProcess	sensory perception	RRH OR2B11 OR5K3 OR5M10 PIEZO2 OR4D5 CHM OR5V1 OR6N2 OR1J1 OR4C45	5.31e-06	1072	41	11	GO:0007600
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	7.51e-06	524	41	8	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	1.03e-05	547	41	8	GO:0007606
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	RRH OR2B11 OR5K3 OR5M10 GPR15 OR4D5 OR5V1 OR6N2 OR1J1 PREX1 OR4C45	6.21e-05	1395	41	11	GO:0007186
GeneOntologyBiologicalProcess	cortisol metabolic process	CACNA1H CYP11A1	2.51e-04	12	41	2	GO:0034650
GeneOntologyBiologicalProcess	synaptic transmission, GABAergic	NALCN GABRA2 GABRA3	4.28e-04	74	41	3	GO:0051932
GeneOntologyBiologicalProcess	glucocorticoid biosynthetic process	CACNA1H CYP11A1	5.78e-04	18	41	2	GO:0006704
GeneOntologyCellularComponent	presynaptic active zone membrane	CACNA1H GABRA2 GABRA3	5.17e-04	78	42	3	GO:0048787
GeneOntologyCellularComponent	GABA-A receptor complex	GABRA2 GABRA3	6.59e-04	19	42	2	GO:1902711
GeneOntologyCellularComponent	GABA receptor complex	GABRA2 GABRA3	8.08e-04	21	42	2	GO:1902710
Domain	GPCR_Rhodpsn_7TM	RRH OR2B11 OR5K3 OR5M10 GPR15 OR4D5 OR5V1 OR6N2 OR1J1	7.52e-06	670	39	9	IPR017452
Domain	7tm_1	RRH OR2B11 OR5K3 OR5M10 GPR15 OR4D5 OR5V1 OR6N2 OR1J1	8.18e-06	677	39	9	PF00001
Domain	G_PROTEIN_RECEP_F1_1	RRH OR2B11 OR5K3 OR5M10 GPR15 OR4D5 OR5V1 OR6N2 OR1J1	8.99e-06	685	39	9	PS00237
Domain	G_PROTEIN_RECEP_F1_2	RRH OR2B11 OR5K3 OR5M10 GPR15 OR4D5 OR5V1 OR6N2 OR1J1	9.64e-06	691	39	9	PS50262
Domain	GPCR_Rhodpsn	RRH OR2B11 OR5K3 OR5M10 GPR15 OR4D5 OR5V1 OR6N2 OR1J1	9.76e-06	692	39	9	IPR000276
Domain	Olfact_rcpt	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1	1.49e-05	393	39	7	IPR000725
Domain	GABAAa_rcpt	GABRA2 GABRA3	6.34e-05	6	39	2	IPR001390
Domain	ATPase_dyneun-rel_AAA	DNAH1 DNAH11	3.81e-04	14	39	2	IPR011704
Domain	Dynein_heavy_chain_D4_dom	DNAH1 DNAH11	3.81e-04	14	39	2	IPR024317
Domain	Dynein_HC_stalk	DNAH1 DNAH11	3.81e-04	14	39	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH1 DNAH11	3.81e-04	14	39	2	IPR013602
Domain	DHC_N2	DNAH1 DNAH11	3.81e-04	14	39	2	PF08393
Domain	MT	DNAH1 DNAH11	3.81e-04	14	39	2	PF12777
Domain	AAA_8	DNAH1 DNAH11	3.81e-04	14	39	2	PF12780
Domain	AAA_5	DNAH1 DNAH11	3.81e-04	14	39	2	PF07728
Domain	DHC_fam	DNAH1 DNAH11	4.39e-04	15	39	2	IPR026983
Domain	Dynein_heavy_dom	DNAH1 DNAH11	4.39e-04	15	39	2	IPR004273
Domain	Dynein_heavy	DNAH1 DNAH11	4.39e-04	15	39	2	PF03028
Domain	GABAA/Glycine_rcpt	GABRA2 GABRA3	1.05e-03	23	39	2	IPR006028
Domain	Neurotransmitter_ion_chnl_CS	GABRA2 GABRA3	3.97e-03	45	39	2	IPR018000
Domain	Neur_chan_memb	GABRA2 GABRA3	4.15e-03	46	39	2	PF02932
Domain	Neur_chan_LBD	GABRA2 GABRA3	4.33e-03	47	39	2	PF02931
Domain	Neur_channel	GABRA2 GABRA3	4.33e-03	47	39	2	IPR006201
Domain	Neur_chan_lig-bd	GABRA2 GABRA3	4.33e-03	47	39	2	IPR006202
Domain	NEUROTR_ION_CHANNEL	GABRA2 GABRA3	4.33e-03	47	39	2	PS00236
Domain	Neurotrans-gated_channel_TM	GABRA2 GABRA3	4.33e-03	47	39	2	IPR006029
Domain	-	GABRA2 GABRA3	4.33e-03	47	39	2	2.70.170.10
Domain	Channel_four-helix_dom	CACNA1H NALCN	6.31e-03	57	39	2	IPR027359
Domain	-	CACNA1H NALCN	6.31e-03	57	39	2	1.20.120.350
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	3.97e-06	417	33	8	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR2B11 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	2.65e-05	389	33	7	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	8.37e-05	636	33	8	M41834
Pathway	BIOCARTA_FLUMAZENIL_PATHWAY	GABRA2 GABRA3	1.89e-04	9	33	2	M22034
Pathway	BIOCARTA_GABA_PATHWAY	GABRA2 GABRA3	2.36e-04	10	33	2	MM1401
Pathway	BIOCARTA_GABA_PATHWAY	GABRA2 GABRA3	2.36e-04	10	33	2	M477
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	6.79e-09	340	42	8	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	6.79e-09	340	42	8	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	7.27e-09	343	42	8	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR2B11 OR5K3 OR5M10 OR4D5 OR5V1 OR6N2 OR1J1 OR4C45	7.78e-09	346	42	8	14611657
Pubmed	Differential roles of GABA(A) receptor subtypes in benzodiazepine-induced enhancement of brain-stimulation reward.	GABRA2 GABRA3	1.42e-06	2	42	2	22763624
Pubmed	Transient expression of GABAA receptor alpha2 and alpha3 subunits in differentiating cerebellar neurons.	GABRA2 GABRA3	1.42e-06	2	42	2	14766194
Pubmed	Molecular and neuronal substrate for the selective attenuation of anxiety.	GABRA2 GABRA3	1.42e-06	2	42	2	11021797
Pubmed	Neural basis of benzodiazepine reward: requirement for α2 containing GABAA receptors in the nucleus accumbens.	GABRA2 GABRA3	1.42e-06	2	42	2	24553732
Pubmed	Reversal of pathological pain through specific spinal GABAA receptor subtypes.	GABRA2 GABRA3	1.42e-06	2	42	2	18202657
Pubmed	Linking GABA(A) receptor subunits to alcohol-induced conditioned taste aversion and recovery from acute alcohol intoxication.	GABRA2 GABRA3	1.42e-06	2	42	2	23147414
Pubmed	Functional expression of the GABA(A) receptor α2 and α3 subunits at synapses between intercalated medial paracapsular neurons of mouse amygdala.	GABRA2 GABRA3	1.42e-06	2	42	2	22666188
Pubmed	Dissecting the role of diazepam-sensitive γ-aminobutyric acid type A receptors in defensive behavioral reactivity to mild threat.	GABRA2 GABRA3	1.42e-06	2	42	2	23067879
Pubmed	Enrichment of GABAA Receptor α-Subunits on the Axonal Initial Segment Shows Regional Differences.	GABRA2 GABRA3	1.42e-06	2	42	2	26973458
Pubmed	Functional mapping of GABA A receptor subtypes in the amygdala.	GABRA2 GABRA3	1.42e-06	2	42	2	15341600
Pubmed	Mutations in DNAH1, which encodes an inner arm heavy chain dynein, lead to male infertility from multiple morphological abnormalities of the sperm flagella.	DNAH1 DNAH11	1.42e-06	2	42	2	24360805
Pubmed	Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric acidA receptors.	GABRA2 GABRA3	1.42e-06	2	42	2	8391122
Pubmed	Specific subtypes of GABAA receptors mediate phasic and tonic forms of inhibition in hippocampal pyramidal neurons.	GABRA2 GABRA3	4.27e-06	3	42	2	16835366
Pubmed	The alpha 1, alpha 2, and alpha 3 subunits of GABAA receptors: comparison in seizure-prone and -resistant mice and during development.	GABRA2 GABRA3	4.27e-06	3	42	2	1356407
Pubmed	The effects of the nonselective benzodiazepine lorazepam and the α2 /α3 subunit-selective GABAA receptor modulators AZD7325 and AZD6280 on plasma prolactin levels.	GABRA2 GABRA3	4.27e-06	3	42	2	27128218
Pubmed	Specific GABAA circuits for visual cortical plasticity.	GABRA2 GABRA3	4.27e-06	3	42	2	15017002
Pubmed	Analysis of the presence and abundance of GABAA receptors containing two different types of alpha subunits in murine brain using point-mutated alpha subunits.	GABRA2 GABRA3	4.27e-06	3	42	2	15304513
Pubmed	Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.	DNAH1 DNAH11	8.53e-06	4	42	2	18492703
Pubmed	Molecular motors: the driving force behind mammalian left-right development.	DNAH1 DNAH11	8.53e-06	4	42	2	10652513
Pubmed	Association study between GABA receptor genes and anxiety spectrum disorders.	GABRA2 GABRA3	8.53e-06	4	42	2	19842164
Pubmed	Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype.	GABRA2 GABRA3	8.53e-06	4	42	2	25865415
Pubmed	The α1, α2, α3, and γ2 subunits of GABAA receptors show characteristic spatial and temporal expression patterns in rhombencephalic structures during normal human brain development.	GABRA2 GABRA3	8.53e-06	4	42	2	26518133
Pubmed	Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon.	GABRA2 GABRA3	8.53e-06	4	42	2	25080596
Pubmed	GABA(A) receptor downregulation in brains of subjects with autism.	GABRA2 GABRA3	8.53e-06	4	42	2	18821008
Pubmed	Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors.	GABRA2 GABRA3	1.42e-05	5	42	2	30104684
Pubmed	GABAA receptor signaling in caudal periaqueductal gray regulates maternal aggression and maternal care in mice.	GABRA2 GABRA3	2.13e-05	6	42	2	20457185
Pubmed	Modelling extracellular domains of GABA-A receptors: subtypes 1, 2, 3, and 5.	GABRA2 GABRA3	2.13e-05	6	42	2	15033447
Pubmed	Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex.	GABRA2 GABRA3	2.98e-05	7	42	2	7560270
Pubmed	Lamina-specific alterations in cortical GABA(A) receptor subunit expression in schizophrenia.	GABRA2 GABRA3	2.98e-05	7	42	2	20843900
Pubmed	Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO).	GABRA2 GABRA3	2.98e-05	7	42	2	35228700
Pubmed	Developmental changes in GABA receptor subunit composition within the gonadotrophin-releasing hormone-1 neuronal system.	GABRA2 GABRA3	2.98e-05	7	42	2	16101898
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH1 DNAH11	2.98e-05	7	42	2	9256245
Pubmed	gamma-Aminobutyric acidA receptors displaying association of gamma 3-subunits with beta 2/3 and different alpha-subunits exhibit unique pharmacological properties.	GABRA2 GABRA3	3.97e-05	8	42	2	8175718
Pubmed	GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1.	GABRA2 GABRA3	3.97e-05	8	42	2	11528422
Pubmed	Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.	MRPL45 THOC2 USP9X TOP3A	5.97e-05	175	42	4	37866880
Pubmed	Inhibitory synapse dysfunction and epileptic susceptibility associated with KIF2A deletion in cortical interneurons.	GABRA2 GABRA3	6.37e-05	10	42	2	36733270
Pubmed	Functional modifications of acid-sensing ion channels by ligand-gated chloride channels.	GABRA2 GABRA3	6.37e-05	10	42	2	21789198
Pubmed	Review: Central non-glucocorticoid inhibitors of the hypothalamo-pituitary-adrenal axis.	GABRA2 GABRA3	7.78e-05	11	42	2	9924185
Pubmed	γ1 GABAA Receptors in Spinal Nociceptive Circuits.	GABRA2 GABRA3	7.78e-05	11	42	2	39137998
Pubmed	Region and layer-specific expression of GABAA receptor isoforms and KCC2 in developing cortex.	GABRA2 GABRA3	7.78e-05	11	42	2	38894703
Pubmed	Chromosomal localization of GABAA receptor subunit genes: relationship to human genetic disease.	GABRA2 GABRA3	9.32e-05	12	42	2	2561974
Pubmed	Involvement of neurotransmitters in the action of growth hormone-releasing hormone antagonist on passive avoidance learning.	GABRA2 GABRA3	1.10e-04	13	42	2	22640814
Pubmed	Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice.	GABRA2 GABRA3	1.10e-04	13	42	2	22569571
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH1 DNAH11	1.28e-04	14	42	2	9373155
Pubmed	Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells.	TCERG1 BAG6 USP9X	2.10e-04	95	42	3	29490077
Pubmed	GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.	GABRA2 GABRA3	2.15e-04	18	42	2	18985723
Pubmed	Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.	GABRA2 GABRA3	2.15e-04	18	42	2	19078961
Pubmed	Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce syncope.	PIEZO2 GABRA2	2.15e-04	18	42	2	37914931
Pubmed	Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus.	GABRA2 GABRA3	2.95e-04	21	42	2	25708312
Pubmed	Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala.	GABRA2 GABRA3	3.24e-04	22	42	2	38736483
Pubmed	The human olfactory receptor gene family.	OR5M10 OR4D5 OR5V1 OR6N2 OR1J1	4.73e-04	541	42	5	14983052
Pubmed	The transcription factor c-Maf controls touch receptor development and function.	CACNA1H PIEZO2	4.90e-04	27	42	2	22345400
Pubmed	TopBP1 controls BLM protein level to maintain genome stability.	USP9X TOP3A	5.66e-04	29	42	2	24239288
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	TNIK THOC2 SLCO2A1 GABRA3	6.63e-04	329	42	4	17474147
Pubmed	Primary Ciliary Dyskinesia	DNAH1 DNAH11	6.90e-04	32	42	2	20301301
Pubmed	Murine txk: a protein tyrosine kinase gene regulated by T cell activation.	DDR2 GABRA2	6.90e-04	32	42	2	7542761
Pubmed	Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.	GABRA2 GABRA3	8.26e-04	35	42	2	37758766
Pubmed	A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis.	PIEZO2 GSG1L2	1.13e-03	41	42	2	23509962
Cytoband	Ensembl 112 genes in cytogenetic band chr3q11	OR5K3 GPR15	1.13e-03	54	42	2	chr3q11
GeneFamily	Dyneins, axonemal	DNAH1 DNAH11	3.81e-04	17	31	2	536
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRA2 GABRA3	4.78e-04	19	31	2	563
GeneFamily	Olfactory receptors, family 5	OR5K3 OR5M10 OR5V1	9.17e-04	112	31	3	152
GeneFamily	X-linked mental retardation\|Angiotensin receptors	THOC2 USP9X	3.71e-03	53	31	2	103
GeneFamily	Olfactory receptors, family 4	OR4D5 OR4C45	2.05e-02	129	31	2	151
Drug	Zolpidem	GABRA2 GABRA3	9.95e-06	3	42	2	DB00425
Drug	etizolam	GABRA2 GABRA3	1.99e-05	4	42	2	ctd:C044610
Drug	Flumazenil	GABRA2 GABRA3	1.99e-05	4	42	2	DB01205
Drug	Eszopiclone	GABRA2 GABRA3	3.31e-05	5	42	2	DB00402
Drug	Lorazepam	GABRA2 GABRA3	3.31e-05	5	42	2	ctd:D008140
Drug	Zopiclone	GABRA2 GABRA3	3.31e-05	5	42	2	DB01198
Drug	Meprobamate	GABRA2 GABRA3	4.96e-05	6	42	2	DB00371
Drug	Flunitrazepam	GABRA2 GABRA3	4.96e-05	6	42	2	DB01544
Drug	Gabrene	SLCO2A1 GABRA2 GABRA3	5.50e-05	40	42	3	CID005361323
Drug	Quazepam	GABRA2 GABRA3	6.94e-05	7	42	2	DB01589
Drug	Adinazolam	GABRA2 GABRA3	9.24e-05	8	42	2	DB00546
Drug	Fludiazepam	GABRA2 GABRA3	9.24e-05	8	42	2	DB01567
Drug	Clotiazepam	GABRA2 GABRA3	9.24e-05	8	42	2	DB01559
Drug	Cinolazepam	GABRA2 GABRA3	9.24e-05	8	42	2	DB01594
Drug	Prazepam	GABRA2 GABRA3	9.24e-05	8	42	2	DB01588
Drug	Halazepam	GABRA2 GABRA3	9.24e-05	8	42	2	DB00801
Drug	Estazolam	GABRA2 GABRA3	9.24e-05	8	42	2	DB01215
Drug	1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane	GABRA2 GABRA3	9.24e-05	8	42	2	ctd:C091518
Drug	tiotidine	GABRA2 GABRA3	1.19e-04	9	42	2	ctd:C023990
Drug	Ethchlorvynol	GABRA2 GABRA3	1.19e-04	9	42	2	DB00189
Drug	Diazepam	GABRA2 GABRA3	1.19e-04	9	42	2	DB00829
Drug	Clonazepam	GABRA2 GABRA3	1.48e-04	10	42	2	DB01068
Drug	Secobarbital	GABRA2 GABRA3	1.48e-04	10	42	2	DB00418
Drug	Chlordiazepoxide	GABRA2 GABRA3	1.48e-04	10	42	2	DB00475
Drug	Metharbital	GABRA2 GABRA3	1.48e-04	10	42	2	DB00463
Drug	Pentobarbital	GABRA2 GABRA3	1.48e-04	10	42	2	DB00312
Drug	Talbutal	GABRA2 GABRA3	1.48e-04	10	42	2	DB00306
Drug	Clobazam	GABRA2 GABRA3	1.48e-04	10	42	2	DB00349
Drug	Butalbital	GABRA2 GABRA3	1.48e-04	10	42	2	DB00241
Drug	Butabarbital	GABRA2 GABRA3	1.48e-04	10	42	2	DB00237
Drug	Bromazepam	GABRA2 GABRA3	1.48e-04	10	42	2	DB01558
Drug	Barbituric acid derivative	GABRA2 GABRA3	1.48e-04	10	42	2	DB01496
Drug	Barbital	GABRA2 GABRA3	1.48e-04	10	42	2	DB01483
Drug	Methylphenobarbital	GABRA2 GABRA3	1.48e-04	10	42	2	DB00849
Drug	Oxazepam	GABRA2 GABRA3	1.48e-04	10	42	2	DB00842
Drug	Hexobarbital	GABRA2 GABRA3	1.48e-04	10	42	2	DB01355
Drug	Aprobarbital	GABRA2 GABRA3	1.48e-04	10	42	2	DB01352
Drug	Amobarbital	GABRA2 GABRA3	1.48e-04	10	42	2	DB01351
Drug	Heptabarbital	GABRA2 GABRA3	1.48e-04	10	42	2	DB01354
Drug	Butethal	GABRA2 GABRA3	1.48e-04	10	42	2	DB01353
Drug	Primidone	GABRA2 GABRA3	1.48e-04	10	42	2	DB00794
Drug	Midazolam	GABRA2 GABRA3	1.48e-04	10	42	2	DB00683
Drug	Flurazepam	GABRA2 GABRA3	1.48e-04	10	42	2	DB00690
Drug	Thiopental	GABRA2 GABRA3	1.81e-04	11	42	2	DB00599
Drug	Alprazolam	GABRA2 GABRA3	1.81e-04	11	42	2	DB00404
Drug	Temazepam	GABRA2 GABRA3	1.81e-04	11	42	2	DB00231
Drug	Nitrazepam	GABRA2 GABRA3	1.81e-04	11	42	2	DB01595
Drug	Lorazepam	GABRA2 GABRA3	1.81e-04	11	42	2	DB00186
Drug	Triazolam	GABRA2 GABRA3	1.81e-04	11	42	2	DB00897
Drug	Clorazepate	GABRA2 GABRA3	1.81e-04	11	42	2	DB00628
Drug	Phenobarbital	GABRA2 GABRA3	1.81e-04	11	42	2	DB01174
Drug	5 beta-pregnanediol	CYP11A1 GABRA2 GABRA3	1.86e-04	60	42	3	CID000012547
Drug	AC1L1J7N	CYP11A1 SLCO2A1 GABRA2	2.25e-04	64	42	3	CID000004902
Drug	etomidate	CYP11A1 GABRA2 GABRA3	3.06e-04	71	42	3	CID000036339
Drug	Gd 7	CYP11A1 PAEP	3.92e-04	16	42	2	CID000092808
Drug	alprazolam	CACNA1H CYP11A1 GABRA2 GABRA3	4.35e-04	193	42	4	CID000002118
Drug	dihydroxyaflavinine	GABRA2 GABRA3	4.44e-04	17	42	2	CID000156857
Drug	Natamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A	RRH GPR15 CHM GABRA2	4.80e-04	198	42	4	3548_UP
Drug	Benzthiazide [91-33-8]; Up 200; 9.2uM; HL60; HT_HG-U133A	RRH MBOAT2 SLCO2A1 GABRA3	4.98e-04	200	42	4	2989_UP
Drug	Nadolol [42200-33-9]; Up 200; 13uM; HL60; HT_HG-U133A	PLAC1 KLF3 SLCO2A1 TOP3A	4.98e-04	200	42	4	3020_UP
Disease	ARTHROGRYPOSIS, DISTAL, TYPE 2B	PIEZO2 NALCN	2.82e-05	6	41	2	C1834523
Disease	Distal arthrogryposis	PIEZO2 NALCN	6.74e-05	9	41	2	cv:C0265213
Disease	osteoarthritis (is_implicated_in)	BAG6 DDR2	6.96e-04	28	41	2	DOID:8398 (is_implicated_in)
Disease	migraine disorder, glucose measurement	CACNA1H OR5V1	8.54e-04	31	41	2	EFO_0004468, MONDO_0005277
Disease	response to allopurinol, uric acid measurement	OR4D5 NALCN	9.10e-04	32	41	2	EFO_0004761, EFO_0006337
Disease	Primary ciliary dyskinesia	DNAH1 DNAH11	1.15e-03	36	41	2	cv:C0008780

Protein segments in the cluster

Peptide	Gene	Start	Entry
CTVENPVTQLIMYMD	CEACAM18	296	A8MTB9
MSHYTTPMVLQQAAI	BAG6	361	P46379
YMISVNMHCSVLLLT	GPR15	111	P49685
TIAFHQTMMCNFLPT	DNAH11	2686	Q96DT5
PNLQYIVMHSIAMTS	CHM	331	P24386
MSKNICISLVTVPYM	OR5M10	136	Q6IEU7
VAHMMYTTIFQITVN	GSG1L2	176	A8MUP6
LAMFKCQTHQTMPVT	RRH	306	O14718
CQTHQTMPVTSILPM	RRH	311	O14718
QDTTTPIQSMMCQYL	PAEP	126	P09466
MYTSHLQQPLMVSLS	KLF3	156	P57682
SYCIMIIIGVENMHN	MBOAT2	86	Q6ZWT7
NDMHYECMTPCQVTS	MIPOL1	91	Q8TD10
FIPVTDHSMNVCMRV	DDR2	166	Q16832
YSQHTQMVMALTLRC	IL17RE	281	Q8NFR9
YTMRLTVQAECPMHL	GABRA2	156	P47869
ICKPLHYATIMTQSM	OR4C45	121	A6NMZ5
KHSTINIVDIYPMMC	ENPP4	361	Q9Y6X5
MIITQTSHCYMTSLG	GABRA3	1	P34903
ICNPLQYHTMMSKTL	OR5K3	126	A6NET4
HYATIMTQSQCVMLV	OR1J1	131	Q8NGS3
CYTTTTVPQMLVNMG	OR2B11	76	Q5JQS5
ICYTTSNVPQMMVHL	OR5V1	71	Q9UGF6
HYPIIMTTTLCAKMA	OR6N2	131	Q8NGY6
YCNIIVPTMDTVQMS	DNAH1	2196	Q9P2D7
AIYQMFHTSVPMLNL	CYP11A1	236	P05108
IICVNVITMSMEHYN	CACNA1H	1626	O95180
HYTLIMNQTVCALLM	OR4D5	131	Q8NGN0
KPQHMPCEALTYMTT	NXPE1	246	Q8N323
MVTVHPFMLNNDVCV	PLAC1	36	Q9HBJ0
CYMNSVIQQLYMIPS	USP9X	1566	Q93008
TVYAMAVMNHHVCPV	TMEM150A	21	Q86TG1
PSHVVQVRCSSMMNQ	MRPL45	191	Q9BRJ2
HLNPMSYTQHCITTM	PREX1	1011	Q8TCU6
SLIACISHNPLYMMV	SLCO2A1	526	Q92959
EMPTSVAYIHSNQIM	TNIK	1281	Q9UKE5
VHKYITSCEMVMAPV	THOC2	846	Q8NI27
AMMQIVSCPYVKTVA	TCERG1	381	O14776
THCSYQMMLPESVAI	STAMBP	351	O95630
CYFVIILNHMVSASM	PIEZO2	1926	Q9H5I5
HLYGQNVTMVMTSVS	TOP3A	76	Q13472
CNMMFSSPLIAQSHY	ZMAT1	126	Q5H9K5
ISVCMNTPMTFEHYP	NALCN	51	Q8IZF0