Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
MousePheno	abnormal sinoatrial node conduction	TBX3 MTO1 PRKAG2 IDUA TBX5	1.87e-06	42	69	5	MP:0006142
MousePheno	abnormal impulse conducting system morphology	TBX3 PRKAG2 TBX5	1.35e-05	10	69	3	MP:0004123
MousePheno	failure of heart looping	EPHB4 TBX3 MED12 TBX5	5.80e-05	43	69	4	MP:0004251
MousePheno	abnormal heart rate	TBX3 TOX FCGR2A CACNA2D2 SCARB1 HEY2 MTO1 PRKAG2 IDUA TBX5	6.11e-05	445	69	10	MP:0001629
MousePheno	abnormal circulating enzyme level	HEXB TBX3 TRMT10A TCF7 ALMS1 TOX FCGR2A ABCA13 PRF1 CECR2 GPN1 LRP1 HPSE2 AASDH SIK3 IDUA SLITRK1 DGAT2L6	8.44e-05	1372	69	18	MP:0001570
MousePheno	sinoatrial block	MTO1 IDUA TBX5	8.91e-05	18	69	3	MP:0010520
MousePheno	abnormal impulse conducting system conduction	TBX3 TOX FCGR2A CECR2 SCARB1 MTO1 PRKAG2 IDUA TBX5	1.46e-04	400	69	9	MP:0003137
MousePheno	abnormal heartbeat	TBX3 TOX FCGR2A CACNA2D2 SCARB1 HEY2 MTO1 PRKAG2 IDUA TBX5	1.63e-04	501	69	10	MP:0004085
MousePheno	abnormal enzyme/coenzyme level	HEXB TBX3 TRMT10A TCF7 ALMS1 TOX FCGR2A ABCA13 PRF1 CECR2 GPN1 LRP1 HPSE2 AASDH SIK3 IDUA SLITRK1 DGAT2L6	1.73e-04	1451	69	18	MP:0005319
MousePheno	abnormal P wave	TBX3 IDUA TBX5	2.16e-04	24	69	3	MP:0004070
Domain	DUF89	ARMT1 PANK4	2.14e-05	2	87	2	IPR002791
Domain	DUF89	ARMT1 PANK4	2.14e-05	2	87	2	PF01937
Domain	HMG_BOX_2	SOX7 TCF7 TOX MAEL	1.16e-04	54	87	4	PS50118
Domain	-	SOX7 TCF7 TOX MAEL	1.25e-04	55	87	4	1.10.30.10
Domain	HMG_box_dom	SOX7 TCF7 TOX MAEL	2.39e-04	65	87	4	IPR009071
Domain	ITI_HC_C	ITIH6 ITIH5	3.18e-04	6	87	2	IPR010600
Domain	Fatty_acid_hydroxylase	MSMO1 SC5D	3.18e-04	6	87	2	IPR006694
Domain	FA_hydroxylase	MSMO1 SC5D	3.18e-04	6	87	2	PF04116
Domain	ITI_HC_C	ITIH6 ITIH5	3.18e-04	6	87	2	PF06668
Domain	DAGAT	MOGAT1 DGAT2L6	4.44e-04	7	87	2	PF03982
Domain	DAGAT	MOGAT1 DGAT2L6	4.44e-04	7	87	2	IPR007130
Domain	-	HEXB HPSE2 IDUA	5.74e-04	35	87	3	3.20.20.80
Domain	VIT	ITIH6 ITIH5	5.90e-04	8	87	2	PF08487
Domain	VIT	ITIH6 ITIH5	5.90e-04	8	87	2	SM00609
Domain	Glyco_hydro_catalytic_dom	HEXB HPSE2 IDUA	7.32e-04	38	87	3	IPR013781
Domain	VIT	ITIH6 ITIH5	9.42e-04	10	87	2	PS51468
Domain	VIT	ITIH6 ITIH5	9.42e-04	10	87	2	IPR013694
Domain	HMG_box	SOX7 TCF7 TOX	1.93e-03	53	87	3	PF00505
Domain	Glycoside_hydrolase_SF	HEXB HPSE2 IDUA	1.93e-03	53	87	3	IPR017853
Domain	HMG	SOX7 TCF7 TOX	2.04e-03	54	87	3	SM00398
Domain	VWA	CACNA2D2 ITIH6 ITIH5	2.26e-03	56	87	3	PF00092
Domain	TF_T-box	TBX3 TBX5	2.79e-03	17	87	2	IPR001699
Domain	TBOX	TBX3 TBX5	2.79e-03	17	87	2	SM00425
Domain	TF_T-box_CS	TBX3 TBX5	2.79e-03	17	87	2	IPR018186
Domain	-	TBX3 TBX5	2.79e-03	17	87	2	2.60.40.820
Domain	TBOX_3	TBX3 TBX5	2.79e-03	17	87	2	PS50252
Domain	T-box	TBX3 TBX5	2.79e-03	17	87	2	PF00907
Domain	TBOX_1	TBX3 TBX5	2.79e-03	17	87	2	PS01283
Domain	TBOX_2	TBX3 TBX5	2.79e-03	17	87	2	PS01264
Domain	-	CACNA2D2 ITIH6 ITIH5	4.99e-03	74	87	3	3.40.50.410
Domain	JmjC	KDM3A KDM3B	5.54e-03	24	87	2	PF02373
Domain	VWFA	CACNA2D2 ITIH6 ITIH5	6.63e-03	82	87	3	PS50234
Domain	VWA	CACNA2D2 ITIH6 ITIH5	7.09e-03	84	87	3	SM00327
Pathway	WP_CHOLESTEROL_METABOLISM	MSMO1 SC5D SCARB1 LRP1 TM7SF2	3.03e-05	72	71	5	M46457
Pathway	KEGG_MEDICUS_REFERENCE_CHOLESTEROL_BIOSYNTHESIS	MSMO1 SC5D TM7SF2	3.38e-05	13	71	3	M47945
Pathway	KEGG_STEROID_BIOSYNTHESIS	MSMO1 SC5D TM7SF2	7.91e-05	17	71	3	M5872
Pathway	WP_GLYCOSAMINOGLYCAN_DEGRADATION	HEXB HPSE2 IDUA	7.91e-05	17	71	3	M39832
Pathway	KEGG_GLYCOSAMINOGLYCAN_DEGRADATION	HEXB HPSE2 IDUA	1.53e-04	21	71	3	M3624
Pathway	WP_8P231_COPY_NUMBER_VARIATION_SYNDROME	SOX7 FCGR2A HEPACAM2 TBX5	1.54e-04	54	71	4	M48073
Pathway	REACTOME_CHOLESTEROL_BIOSYNTHESIS	MSMO1 SC5D TM7SF2	3.28e-04	27	71	3	M16227
Pathway	REACTOME_CHOLESTEROL_BIOSYNTHESIS	MSMO1 SC5D TM7SF2	3.28e-04	27	71	3	MM14735
Pubmed	Arid3b is essential for second heart field cell deployment and heart patterning.	SOX7 KDM3A TBX3 HEY2 TBX5	1.15e-07	43	94	5	25336743
Pubmed	MyoR modulates cardiac conduction by repressing Gata4.	TBX3 CACNA2D2 TBX5	2.26e-06	10	94	3	25487574
Pubmed	A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo.	MSMO1 SC5D SCARB1 TM7SF2	3.09e-06	37	94	4	26108225
Pubmed	Genome-wide association study of PR interval.	TBX3 BCAT1 TBX5	4.13e-06	12	94	3	20062060
Pubmed	Loss of Tbx2 delays optic vesicle invagination leading to small optic cups.	TBX3 PMEL TBX5	6.81e-06	14	94	3	19576202
Pubmed	A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification.	ARHGAP11A ARHGAP11B	7.23e-06	2	94	2	27957544
Pubmed	Protooncogenic Role of ARHGAP11A and ARHGAP11B in Invasive Ductal Carcinoma: Two Promising Breast Cancer Biomarkers.	ARHGAP11A ARHGAP11B	7.23e-06	2	94	2	38046902
Pubmed	Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases.	TRMU MTO1	7.23e-06	2	94	2	15509579
Pubmed	Molecular characterization of putative modulatory factors in two Spanish families with A1555G deafness.	TRMU MTO1	7.23e-06	2	94	2	18391568
Pubmed	Identification of a novel percent mammographic density locus at 12q24.	TBX3 TBX5	7.23e-06	2	94	2	22532574
Pubmed	Two mutations produce intron insertion in mRNA and elongated beta-subunit of human beta-hexosaminidase.	HEXB IDUA	7.23e-06	2	94	2	2170400
Pubmed	ArhGAP11A mediates amyloid-β generation and neuropathology in an Alzheimer's disease-like mouse model.	ARHGAP11A ARHGAP11B	7.23e-06	2	94	2	37302068
Pubmed	TBX3 and TBX5 duplication: A family with an atypical overlapping Holt-Oram/ulnar-mammary syndrome phenotype.	TBX3 TBX5	7.23e-06	2	94	2	33930582
Pubmed	Control of sinus venous valve and sinoatrial node development by endocardial NOTCH1.	TBX3 HEY2 TBX5	1.04e-05	16	94	3	31591643
Pubmed	Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia.	LRP1 CD68 MERTK	1.26e-05	17	94	3	30647151
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 KDM3A CECR2 KDM3B SMPD4 IGSF9 SIK3 ARHGAP11A ARHGAP11B	1.38e-05	529	94	9	14621295
Pubmed	Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.	TOX ABCA13 MAEL	1.80e-05	19	94	3	25367360
Pubmed	Transcriptional Patterning of the Ventricular Cardiac Conduction System.	TBX3 TBX5	2.16e-05	3	94	2	32290757
Pubmed	The ROS-sensitive microRNA-9/9* controls the expression of mitochondrial tRNA-modifying enzymes and is involved in the molecular mechanism of MELAS syndrome.	TRMU MTO1	2.16e-05	3	94	2	25149473
Pubmed	Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family.	TBX3 TBX5	2.16e-05	3	94	2	8988164
Pubmed	Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease.	TBX3 TBX5	2.16e-05	3	94	2	22543974
Pubmed	TCF-1 and TOX regulate the memory formation of intestinal group 2 innate lymphoid cells in asthma.	TCF7 TOX	2.16e-05	3	94	2	39245681
Pubmed	Expression of Drosophila omb-related T-box genes in the developing human and mouse neural retina.	TBX3 TBX5	2.16e-05	3	94	2	11726608
Pubmed	Zfp703 Is a Wnt/β-Catenin Feedback Suppressor Targeting the β-Catenin/Tcf1 Complex.	ZNF703 TCF7	2.16e-05	3	94	2	27090637
Pubmed	Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans.	SCARB1 LRP1	2.16e-05	3	94	2	29853565
Pubmed	Genetic analyses in a variant of Mayer-Rokitansky-Kuster-Hauser syndrome (MURCS association).	TBX3 TBX5	2.16e-05	3	94	2	18726671
Pubmed	Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells.	TCF7 TOX	2.16e-05	3	94	2	29768177
Pubmed	cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins.	KDM3B FAM53C	2.16e-05	3	94	2	11087669
Pubmed	Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium.	EPHB4 HEY2 TBX5	3.71e-05	24	94	3	25497097
Pubmed	Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms.	TCF7 TOX	4.32e-05	4	94	2	32396847
Pubmed	Combined Loss of JMJD1A and JMJD1B Reveals Critical Roles for H3K9 Demethylation in the Maintenance of Embryonic Stem Cells and Early Embryogenesis.	KDM3A KDM3B	4.32e-05	4	94	2	29526734
Pubmed	Protein complex interactor analysis and differential activity of KDM3 subfamily members towards H3K9 methylation.	KDM3A KDM3B	4.32e-05	4	94	2	23593242
Pubmed	Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis.	ARHGAP11A ARHGAP11B	4.32e-05	4	94	2	31883789
Pubmed	In-silico QTL mapping of postpubertal mammary ductal development in the mouse uncovers potential human breast cancer risk loci.	TBX3 TBX5	4.32e-05	4	94	2	25552398
Pubmed	Human TBX1 missense mutations cause gain of function resulting in the same phenotype as 22q11.2 deletions.	TBX3 TBX5	4.32e-05	4	94	2	17273972
Pubmed	Molecular cloning and expression of murine thromboxane synthase.	TBX3 TBX5	4.32e-05	4	94	2	7688225
Pubmed	JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor.	KDM3A KDM3B	4.32e-05	4	94	2	16603237
Pubmed	Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development.	ARHGAP11A ARHGAP11B	4.32e-05	4	94	2	36924763
Pubmed	Evidence of a role for T-box genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity.	TBX3 TBX5	4.32e-05	4	94	2	8798150
Pubmed	Novel copy number variants and major limb reduction malformation: Report of three cases.	TBX3 TBX5	4.32e-05	4	94	2	26749485
Pubmed	Interaction network of human early embryonic transcription factors.	ZNF703 TBX3 TNRC18 ALMS1 ATXN1L MED12 PRRC2B	4.85e-05	351	94	7	38297188
Pubmed	Myocardial Tbx20 regulates early atrioventricular canal formation and endocardial epithelial-mesenchymal transition via Bmp2.	TBX3 HEY2 TBX5	5.34e-05	27	94	3	21983003
Pubmed	Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2.	TBX3 HEY2 TBX5	5.96e-05	28	94	3	15901664
Pubmed	Critical role of phosphodiesterase 2A in mouse congenital heart defects.	TBX3 HEY2 TBX5	5.96e-05	28	94	3	29409032
Pubmed	Cholesteryl ester transfer protein (CETP) expression enhances HDL cholesteryl ester liver delivery, which is independent of scavenger receptor BI, LDL receptor related protein and possibly LDL receptor.	SCARB1 LRP1	7.19e-05	5	94	2	17055779
Pubmed	Association of the 3' UTR transcription factor LBP-1c/CP2/LSF polymorphism with late-onset Alzheimer's disease.	SCARB1 LRP1	7.19e-05	5	94	2	12555245
Pubmed	Study of modifiers factors associated to mitochondrial mutations in individuals with hearing impairment.	TRMU MTO1	7.19e-05	5	94	2	19338775
Pubmed	Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.	TBX3 TBX5	7.19e-05	5	94	2	22706305
Pubmed	Development and maturation of invariant NKT cells in the presence of lysosomal engulfment.	HEXB IDUA	7.19e-05	5	94	2	19637231
Pubmed	Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay.	TBX3 TBX5	7.19e-05	5	94	2	19592579
Pubmed	Complement component C1q regulates macrophage expression of Mer tyrosine kinase to promote clearance of apoptotic cells.	LRP1 MERTK	7.19e-05	5	94	2	22422887
Pubmed	Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development.	TBX3 TBX5	7.19e-05	5	94	2	8853987
Pubmed	The transcription factor TCF-1 enforces commitment to the innate lymphoid cell lineage.	TCF7 TOX	7.19e-05	5	94	2	31358996
Pubmed	The level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cup.	TBX3 TBX5	7.19e-05	5	94	2	17173667
Pubmed	Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo.	SCARB1 LRP1	7.19e-05	5	94	2	18992221
Pubmed	Mouse thromboxane A2 receptor: cDNA cloning, expression and northern blot analysis.	TBX3 TBX5	7.19e-05	5	94	2	1375456
Pubmed	Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid.	SCARB1 LRP1	7.19e-05	5	94	2	11240025
Pubmed	NOTCH maintains developmental cardiac gene network through WNT5A.	EPHB4 HEY2 TBX5	8.96e-05	32	94	3	30347193
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	KDM3A PRMT5 KDM3B	9.84e-05	33	94	3	26864203
Pubmed	Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells.	FCGR2A PRF1	1.08e-04	6	94	2	27403737
Pubmed	Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q).	KDM3B FAM53C	1.08e-04	6	94	2	11161817
Pubmed	Reduced sodium channel function unmasks residual embryonic slow conduction in the adult right ventricular outflow tract.	TBX3 HEY2	1.08e-04	6	94	2	23661717
Pubmed	Somatic gene therapy for dyslipidemias.	SCARB1 LRP1	1.08e-04	6	94	2	10482304
Pubmed	Lack of genetic interaction between Tbx20 and Tbx3 in early mouse heart development.	TBX3 TBX5	1.08e-04	6	94	2	23936153
Pubmed	The transcriptional repressor Tbx3 delineates the developing central conduction system of the heart.	TBX3 TBX5	1.08e-04	6	94	2	15158141
Pubmed	Suppression of lymphoma and epithelial malignancies effected by interferon gamma.	PRF1 MERTK	1.08e-04	6	94	2	12093877
Pubmed	Perforin- and granzyme-mediated cytotoxic effector functions are essential for protection against Francisella tularensis following vaccination by the defined F. tularensis subsp. novicida ΔfopC vaccine strain.	FCGR2A PRF1	1.08e-04	6	94	2	22493083
Pubmed	Microarray analysis of Tbx5-induced genes expressed in the developing heart.	HEY2 TBX5	1.08e-04	6	94	2	16894625
Pubmed	H3K9 Demethylases JMJD1A and JMJD1B Control Prospermatogonia to Spermatogonia Transition in Mouse Germline.	KDM3A KDM3B	1.08e-04	6	94	2	32679061
Pubmed	Evolution of mouse T-box genes by tandem duplication and cluster dispersion.	TBX3 TBX5	1.08e-04	6	94	2	8878690
Pubmed	An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo.	LRP1 MERTK	1.08e-04	6	94	2	24509082
Pubmed	Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis.	TBX3 TBX5	1.50e-04	7	94	2	22203979
Pubmed	The sinus venosus progenitors separate and diversify from the first and second heart fields early in development.	TBX3 TBX5	1.50e-04	7	94	2	20110338
Pubmed	A census of human transcription factors: function, expression and evolution.	SOX7 TBX3 TCF7 MAFA HEY2 SIX5 MAEL ZNF230 TFAP2C TBX5	1.75e-04	908	94	10	19274049
Pubmed	Atrial identity is determined by a COUP-TFII regulatory network.	HEY2 TBX5	2.00e-04	8	94	2	23725765
Pubmed	Npa3 interacts with Gpn3 and assembly factor Rba50 for RNA polymerase II biogenesis.	RPAP1 GPN1	2.00e-04	8	94	2	32985767
Pubmed	A combined analysis of genomic and primary protein structure defines the phylogenetic relationship of new members if the T-box family.	TBX3 TBX5	2.00e-04	8	94	2	9503012
Pubmed	A 3-Mb map of a large Segmental duplication overlapping the alpha7-nicotinic acetylcholine receptor gene (CHRNA7) at human 15q13-q14.	ARHGAP11A ARHGAP11B	2.00e-04	8	94	2	11829490
Pubmed	Tbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodeling.	TBX3 TBX5	2.00e-04	8	94	2	17460765
Pubmed	Genomic organization of the DGAT2/MOGAT gene family in cattle (Bos taurus) and other mammals.	MOGAT1 DGAT2L6	2.00e-04	8	94	2	14970677
Pubmed	Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes.	PRMT5 MED12	2.00e-04	8	94	2	23749998
Pubmed	Gradual differentiation and confinement of the cardiac conduction system as indicated by marker gene expression.	TBX3 CACNA2D2	2.00e-04	8	94	2	31306714
Pubmed	Embryonic Microglia Interact with Hypothalamic Radial Glia during Development and Upregulate the TAM Receptors MERTK and AXL following an Insult.	CD68 MERTK	2.57e-04	9	94	2	33406432
Pubmed	Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region.	ARHGAP11A ARHGAP11B	2.57e-04	9	94	2	17554679
Pubmed	Mechanisms of immunity to Ehrlichia muris: a model of monocytotropic ehrlichiosis.	FCGR2A PRF1	2.57e-04	9	94	2	14742542
Pubmed	Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction.	TBX3 TBX5	3.21e-04	10	94	2	32672536
Pubmed	Msx1 and Msx2 are functional interacting partners of T-box factors in the regulation of Connexin43.	TBX3 TBX5	3.21e-04	10	94	2	18285513
Pubmed	Development and differentiation of early innate lymphoid progenitors.	TCF7 TOX	3.21e-04	10	94	2	29183988
Pubmed	Dynamic expression of Tbx2 subfamily genes in development of the mouse reproductive system.	TBX3 TBX5	3.21e-04	10	94	2	22223620
Pubmed	Pitx1 determines the morphology of muscle, tendon, and bones of the hindlimb.	TBX3 TBX5	3.21e-04	10	94	2	16989801
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	USP34 ALMS1 TOX KDM3B SIK3	3.73e-04	225	94	5	12168954
Pubmed	Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy.	TBX3 TBX5	3.91e-04	11	94	2	17668378
Pubmed	Tbx6, a mouse T-Box gene implicated in paraxial mesoderm formation at gastrulation.	TBX3 TBX5	3.91e-04	11	94	2	8954725
Pubmed	Mechanism Sharing Between Genetic and Gestational Hypoxia-Induced Cardiac Anomalies.	HEY2 TBX5	3.91e-04	11	94	2	30151366
Pubmed	Functional synergy of a human-specific and an ape-specific metabolic regulator in human neocortex development.	ARHGAP11A ARHGAP11B	3.91e-04	11	94	2	38658571
Pubmed	The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation.	HEY2 TBX5	3.91e-04	11	94	2	11784028
Pubmed	Bmp4 from the optic vesicle specifies murine retina formation.	TBX3 PMEL	3.91e-04	11	94	2	25792196
Pubmed	The HAND1 frameshift A126FS mutation does not cause hypoplastic left heart syndrome in mice.	HEY2 TBX5	3.91e-04	11	94	2	29016838
Pubmed	PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors.	PRMT5 CD68	3.91e-04	11	94	2	37883229
Pubmed	Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.	KDM3A PTPN7 KDM3B	4.06e-04	53	94	3	36265442
GeneFamily	Fatty acid hydroxylase domain containing	MSMO1 SC5D	1.40e-04	6	56	2	552
GeneFamily	Diacylglycerol O-acyltransferase 2 family	MOGAT1 DGAT2L6	2.61e-04	8	56	2	1235
GeneFamily	Olfactory receptors, family 10	OR10G9 OR10G7 OR10G4	1.12e-03	66	56	3	157
GeneFamily	Cadherin related	CDHR2 DCHS1	1.24e-03	17	56	2	24
GeneFamily	T-boxes	TBX3 TBX5	1.40e-03	18	56	2	766
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM3A KDM3B	2.49e-03	24	56	2	485
GeneFamily	Ataxins\|Trinucleotide repeat containing	TNRC18 MED12	2.70e-03	25	56	2	775
GeneFamily	Calcium voltage-gated channel subunits	CACNB3 CACNA2D2	2.92e-03	26	56	2	253
GeneFamily	Immunoglobulin like domain containing	FCGR2A IGSF9 HEPACAM2 MERTK	3.00e-03	193	56	4	594
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	SCARB1 CD68	3.15e-03	27	56	2	1253
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP11A ARHGAP11B	1.05e-02	50	56	2	721
GeneFamily	Fibronectin type III domain containing	EPHB4 IGSF9 MERTK	1.34e-02	160	56	3	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	IGSF9 HEPACAM2 MERTK	1.36e-02	161	56	3	593
Coexpression	SCHMIDT_POR_TARGETS_IN_LIMB_BUD_UP	MSMO1 SC5D TM7SF2 AASDH	2.24e-06	27	91	4	M2383
Coexpression	SCHMIDT_POR_TARGETS_IN_LIMB_BUD_UP	MSMO1 SC5D TM7SF2 AASDH	2.61e-06	28	91	4	MM1310
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBX3 FAM13C LRP1 HPSE2 CSMD2 ITIH5 TBX5	1.64e-07	197	91	7	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCF7 TOX GJB4 TM7SF2 PGLYRP2 AASDH	6.30e-07	149	91	6	efa30fcd9370f98eb7445f295eb4d0305ff455c3
ToppCell	Monocytes-Tissue-resident_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	FCGR2A SERPINF1 TLR5 CD68 BCAT1 CTNND1	2.59e-06	190	91	6	07215e8f292cb54c670037aaf28393cddbe5548c
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBX3 FAM13C FAM178B HPSE2 PGLYRP2 ITIH5	3.29e-06	198	91	6	d1827e3707b929e3a3562989a0c11537d344e164
ToppCell	distal-2-Hematologic-IGSF21+_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FCGR2A SERPINF1 BCAT1 DNAAF9 MERTK TFAP2C	3.29e-06	198	91	6	bcb62e466fc9b9b58cef30a87b98101d19a82ed4
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF703 FCGR2A LRP1 CD68 CTNND1 MERTK	3.39e-06	199	91	6	18b6087863fda22e3e2a2167e7daeb347df1d95b
ToppCell	Sigmoid-Macrophage-Macrophage\|Sigmoid / Region, Cell class and subclass	FCGR2A SERPINF1 LRP1 CD68 CTNND1 MERTK	3.48e-06	200	91	6	9ee3a799de7bade1bfe94b6827461633f02bc1dc
ToppCell	mLN-(6)_Macrophage-(61)_LYVE1_Macrophage\|mLN / shred on region, Cell_type, and subtype	MOGAT1 FCGR2A LRP1 CD68 BCAT1 MERTK	3.48e-06	200	91	6	a20f5ec61d492d8a2adf695ec304b5d57296aa8f
ToppCell	mild-Non-classical_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF703 FCGR2A LRP1 CD68 BCAT1 MERTK	3.48e-06	200	91	6	334bab6bf93d455f3526e817ea5785d8b6ee531c
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|mLN / Region, Cell class and subclass	MOGAT1 FCGR2A LRP1 CD68 BCAT1 MERTK	3.48e-06	200	91	6	89cf739a3c2f5d30e547404f2f2ec6500cd1d65d
ToppCell	Sigmoid-(6)_Macrophage-(60)_Macrophage\|Sigmoid / shred on region, Cell_type, and subtype	FCGR2A SERPINF1 LRP1 CD68 CTNND1 MERTK	3.48e-06	200	91	6	ad84a83a5a1893f7b053d39eddeca851463a8ff0
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LEMD3 FAM178B HEPACAM2 CSMD2 ITIH5	7.94e-06	133	91	5	386c9bbd9bab62209a67ebae6cd6ac0d7cef0a2d
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TOX CECR2 TM7SF2 ARHGAP11B OR10G4	1.29e-05	147	91	5	e99197e3c2e9d63153cc55ae62b30b8363c2267e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TOX CHTF18 ASB4 ZNF230 PRKAG2	1.61e-05	154	91	5	cd99428c282d566b5dbd31fd5a0371b7ffe9ffa2
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRMT10A TCF7 MOGAT1 TM7SF2 TBX5	1.83e-05	158	91	5	6d2709b387945c015faa223c20d22b52a4082140
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN7 TCF7 TOX PRF1 PGLYRP2	1.88e-05	159	91	5	776139481f2d3630461b4dabca606ebf6e6f034e
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN7 TCF7 TOX PRF1 PGLYRP2	1.88e-05	159	91	5	bbb19e2f0b7cee70836fa96dc22f888cbc403d28
ToppCell	facs-Heart-LV-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN7 TCF7 TOX PRF1 PGLYRP2	2.45e-05	168	91	5	18c266162a879544c0103d9dff0270af68964f9e
ToppCell	facs-Heart-LV-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN7 TCF7 TOX PRF1 PGLYRP2	2.45e-05	168	91	5	cb1506cd43a4f36f9024cc9b8e5319365498d244
ToppCell	facs-Heart-LV-3m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN7 TCF7 GJB4 PRF1 PGLYRP2	2.60e-05	170	91	5	2491f3849e34b0ccd06015fa59d15e3d7963c76d
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPN7 TCF7 TOX PRF1 PGLYRP2	2.60e-05	170	91	5	282afbbea5c88d973cf44727c473a3615f0f02a3
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN7 TCF7 TOX PRF1 PGLYRP2	2.90e-05	174	91	5	986e591d3d46009e53548dfa1f2126cf31063ef4
ToppCell	TCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type-4\|TCGA-Adrenal / Sample_Type by Project: Shred V9	TBX3 MSMO1 SCARB1 SIX5 ASB4	2.90e-05	174	91	5	15e2b9f46404ff9575e149024b24cb17b50b02b5
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN7 TCF7 TOX PRF1 PGLYRP2	2.90e-05	174	91	5	785be49a2dbbb1dff0fbced1b48b942c2f4a508d
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPN7 TCF7 TOX PRF1 PGLYRP2	2.90e-05	174	91	5	7c8cc5c2872fc7bcca7ebddaf5a6f20e617a2674
ToppCell	Pericytes-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	TBX3 FAM13C HEY2 HPSE2 TBX5	2.98e-05	175	91	5	ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPN7 TCF7 TOX PRF1 PGLYRP2	3.15e-05	177	91	5	d6b7d387e7485ff52ce27f51df8b8050f49fd941
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HEXB MOGAT1 LRP1 CD68 ITIH5	3.24e-05	178	91	5	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	facs-Heart-RA-18m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN7 TCF7 TOX PRF1 PGLYRP2	3.41e-05	180	91	5	9be0af61d496a29d737bb772ad09864797994299
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Mesenchymal-Mes\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TBX3 PRF1 HEY2 SIX5 ITIH5	3.41e-05	180	91	5	1ade66352570a3f869e21e1055d0a65fbf56c61d
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Mesenchymal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TBX3 PRF1 HEY2 SIX5 ITIH5	3.41e-05	180	91	5	f118c580134bdf3027e2218690cfc8a93468c1ae
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Mesenchymal-Mes-Pericyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TBX3 PRF1 HEY2 SIX5 ITIH5	3.50e-05	181	91	5	634a4f4e5942473e60d08d0b0936407b04bc6b7c
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Mesenchymal-Mes-Pericyte-Peri_L1-6_MUSTN1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TBX3 PRF1 HEY2 SIX5 ITIH5	3.50e-05	181	91	5	c2938cf1f5d4875be07a56a1f36c94f8eab37d99
ToppCell	Pericytes-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	TBX3 FAM13C DCHS1 HEY2 TBX5	3.79e-05	184	91	5	cd10d351d91a81dd6dc806cb4e0c8d7861c98e0b
ToppCell	critical-Epithelial-Ionocyte\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SC5D FAM13C SERPINF1 HEPACAM2 ITIH5	3.79e-05	184	91	5	58d36577eff814d46d72f031f3533d71549e3d6e
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FCGR2A LRP1 CD68 BCAT1 MERTK	3.89e-05	185	91	5	7bff05d8d34616adbaa0ea0b69eb30aa906bb9f8
ToppCell	wk_08-11-Epithelial-PNS-COL20A1+_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TOX ITIH6 CSMD2 TFAP2C SLITRK1	3.89e-05	185	91	5	abec2a49fe0f0fa4cba49347207a1ee317333657
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 SERPINF1 LRP1 HPSE2 TBX5	3.89e-05	185	91	5	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Monocytic-Nonclassical_monocytes\|lymph-node_spleen / Manually curated celltypes from each tissue	ZNF703 FCGR2A CD68 BCAT1 MERTK	3.99e-05	186	91	5	d7da5edb2ee36f96cdd7e27eb9afcc1cbfd52bb6
ToppCell	control-immature_Neutrophil\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SCARB1 TLR5 IGSF9 CTNND1 FAM53C	4.31e-05	189	91	5	bdfd120900ba58d5e54765f7b576e1f8cc2401bf
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN7 TCF7 TOX PRF1 PGLYRP2	4.31e-05	189	91	5	224d8304cc87b8573a4a78cf88a49d41564f7a47
ToppCell	Control-Myeloid-transitional_Macro\|Control / Disease group,lineage and cell class （2021.01.30）	ZNF703 SCARB1 SERPINF1 BCAT1 MERTK	4.53e-05	191	91	5	3ed0b1ff628a165e3c92c2e493206015f57dccfe
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FCGR2A LRP1 CD68 BCAT1 MERTK	4.53e-05	191	91	5	51f5af610983aa73b9f4ece6f27d281ebff89a04
ToppCell	Control-Myeloid\|Control / group, cell type (main and fine annotations)	HEXB FCGR2A LRP1 CD68 MERTK	4.53e-05	191	91	5	9c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FCGR2A LRP1 CD68 BCAT1 MERTK	4.53e-05	191	91	5	8fd6bdc9d2b1c8d364221d7bc68d03921b668ab5
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	FCGR2A BCAT1 DNAAF9 MERTK ARHGAP11B	4.64e-05	192	91	5	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	EPHB4 HEXB CHTF18 LRP1 CTNND1	4.64e-05	192	91	5	af453a179f3fdd4ae870f1d98a485e8c9fd726ac
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Monocytic-Nonclassical_Monocyte\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	EPHB4 HEXB CHTF18 LRP1 CTNND1	4.64e-05	192	91	5	176b9c1dd2c91bca46e12fa5060bfe590dc18246
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Monocytic\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	EPHB4 HEXB CHTF18 LRP1 CTNND1	4.64e-05	192	91	5	81f93b4c853f176c91b5ddef34238e37047a0e69
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HPSE2 PGLYRP2 CSMD2 DGAT2L6 TBX5	4.76e-05	193	91	5	e5016959f24370579a8770787e96869f264cf7b3
ToppCell	Macrophages-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	HEXB FCGR2A LRP1 CD68 ITIH5	4.76e-05	193	91	5	a6694b33adcdb17cdd1567eb9507dbf06e6468d8
ToppCell	Macrophages-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	HEXB FCGR2A LRP1 CD68 ITIH5	4.76e-05	193	91	5	18534bd60bdd1ce51f948380c78017679931b8b1
ToppCell	severe-Myeloid-CD16_Monocytes\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ZNF703 LRP1 CD68 BCAT1 MERTK	4.87e-05	194	91	5	1b33248b8a7cb914783bcf9e6a80481b4db7e0e8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FCGR2A LRP1 BCAT1 MERTK TFAP2C	4.87e-05	194	91	5	45708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCell	IIH-mono3-\|IIH / Condition, Cell_class and T cell subcluster	FCGR2A CECR2 COX6A2 CD68 BCAT1	4.99e-05	195	91	5	28a858b04a7b413916c07a8d880f5ea02e985461
ToppCell	Monocytes-M2-like_CD16+_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	FCGR2A TLR5 LRP1 CD68 MERTK	4.99e-05	195	91	5	10fa47bdcf6c9784ea930b75a5861e139421feed
ToppCell	Monocytes-NUPR1+_Monocytes\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	FCGR2A SCARB1 CD68 DNAAF9 MERTK	4.99e-05	195	91	5	5e12201ce7ba912e7faa123ca200e609252ba288
ToppCell	390C-Myeloid-Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	HEXB FCGR2A LRP1 CD68 ITIH5	4.99e-05	195	91	5	ba494be431916d43c1d480f65bed674c0722c710
ToppCell	IIH-mono3\|IIH / Condition, Cell_class and T cell subcluster	FCGR2A CECR2 COX6A2 CD68 BCAT1	4.99e-05	195	91	5	c6dd5af582d257be64b718e30f60220c1bf1738a
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_monocytic\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FCGR2A TLR5 LRP1 CD68 PRKAG2	5.12e-05	196	91	5	89ff93cbfbe39fbdf2498e8fdc5d61a0ecb26fc9
ToppCell	COVID-19_Moderate-Non-classical_Monocyte\|COVID-19_Moderate / disease group, cell group and cell class	ZNF703 FCGR2A LRP1 CD68 MERTK	5.12e-05	196	91	5	256c557fa11414c9d2cbb1fcff33f482ee1c78ac
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FCGR2A TLR5 LRP1 CD68 PRKAG2	5.12e-05	196	91	5	09574bfeb1d3da53b5471cfb0602946d328b3b5c
ToppCell	Non-neuronal-Postmitotic-Microglia\|World / Primary Cells by Cluster	FCGR2A SERPINF1 COX6A2 CD68 MERTK	5.12e-05	196	91	5	0358c5211a2083a2188064af15011733a712211d
ToppCell	remission-Non-classical_Monocyte\|remission / disease stage, cell group and cell class	ZNF703 FCGR2A CD68 BCAT1 MERTK	5.12e-05	196	91	5	049d995986c20ce066bd64fcc2d2f1c2f8899883
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_macrophage\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FCGR2A LRP1 CD68 BCAT1 MERTK	5.24e-05	197	91	5	e3349a381723393cd255f202afedd0c99037939b
ToppCell	control-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	HEXB FCGR2A LRP1 KDM3B CD68	5.24e-05	197	91	5	df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_macrophage-macrophage\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FCGR2A LRP1 CD68 BCAT1 MERTK	5.24e-05	197	91	5	e567886d69c6ea8dec87019c2ebc593793cb3107
ToppCell	normal_Lymph_Node-Myeloid_cells-Undetermined\|normal_Lymph_Node / Location, Cell class and cell subclass	FCGR2A SERPINF1 LRP1 CD68 BCAT1	5.24e-05	197	91	5	d8dc65b580191827ab6bbad5e29f0089419ebaef
ToppCell	distal-Hematologic-Interstitial_Macrophage-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FCGR2A SERPINF1 CD68 BCAT1 MERTK	5.24e-05	197	91	5	3b859c3bbb71858b97ce670bd507e67c377b88eb
ToppCell	distal-3-mesenchymal-Fibromyocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FAM13C HPSE2 MAEL CSMD2 TBX5	5.37e-05	198	91	5	dc93886439a378a0c71e99acb8081bfb6b6d467b
ToppCell	COVID-19-Myeloid\|COVID-19 / group, cell type (main and fine annotations)	FCGR2A LRP1 CD68 MERTK PRKAG2	5.37e-05	198	91	5	33f0a919188a67d2a876b52c61a1cec2c9747969
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBX3 CACNB3 FAM13C HPSE2 TBX5	5.37e-05	198	91	5	63f7d25201613bd3404c28fb936954190bca91d3
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBX3 CACNB3 FAM13C HPSE2 TBX5	5.37e-05	198	91	5	a73534b6ca202c277a70a52281d5b97a3e6cb8ef
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBX3 CACNB3 FAM13C HPSE2 TBX5	5.37e-05	198	91	5	d1e1bdd36c84e1bac21ba137f018defe98456a8c
ToppCell	distal-Hematologic-IGSF21+_Dendritic-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FCGR2A SERPINF1 BCAT1 DNAAF9 MERTK	5.37e-05	198	91	5	323b4e6c31e18227546bb30566c1d872fda45e36
ToppCell	Monocytes-Phagocytic_CD16+_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	FCGR2A LRP1 CD68 BCAT1 MERTK	5.37e-05	198	91	5	09009cc966bf1503c3b15dfa079a6c5f6ad1f507
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_macrophage\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FCGR2A LRP1 CD68 BCAT1 MERTK	5.37e-05	198	91	5	c08018f099a381a66993cb60288954a6e47f105f
ToppCell	Monocytes\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ZNF703 FCGR2A LRP1 CD68 CTNND1	5.37e-05	198	91	5	8beccf03c9ec9cd02a96107a9d7ca9a6764c6a61
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FCGR2A LRP1 CD68 BCAT1 MERTK	5.37e-05	198	91	5	27cc7f786fb8cb230589d762a4e51b46265c1f19
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-macrophage\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FCGR2A LRP1 CD68 BCAT1 MERTK	5.37e-05	198	91	5	76db943db8b5483754f38e4c6af7f5955cec420c
ToppCell	10x5'-Lung\|World / Manually curated celltypes from each tissue	HEXB FCGR2A LRP1 CD68 ITIH5	5.37e-05	198	91	5	a5cbe60caadd5b975906ecbc4eaa9795e4ebf885
ToppCell	moderate-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	HEXB LRP1 CD68 BCAT1 PRKAG2	5.50e-05	199	91	5	3895e367a33ac0316f96a64c07574de99684f4b7
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FCGR2A LRP1 CD68 BCAT1 MERTK	5.50e-05	199	91	5	b827dd8a249f904a0ff930a6c4d3b00fb7bc6fb1
ToppCell	Non-neuronal-Postmitotic\|World / Primary Cells by Cluster	FCGR2A SERPINF1 CD68 MERTK ITIH5	5.50e-05	199	91	5	f6a9119ad32d9f0173c432de353b5315a7cf01ad
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF703 FCGR2A CD68 BCAT1 MERTK	5.50e-05	199	91	5	99eec995aa20ac22a8dd045382bd15a15db0b87a
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FCGR2A LRP1 CD68 BCAT1 MERTK	5.50e-05	199	91	5	bcf7d15b6a08b24e7dd0ce106817659cb976f833
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FCGR2A LRP1 CD68 BCAT1 MERTK	5.50e-05	199	91	5	0f3ce61bbae69f7e333ed8dacf7257645624e163
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	ZNF703 FCGR2A CD68 BCAT1 MERTK	5.50e-05	199	91	5	aca9f75c690c6ed952bcbdc7e1e7eef7719f54ca
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FCGR2A LRP1 CD68 BCAT1 MERTK	5.50e-05	199	91	5	c0dcdda30485bb920d3706dcfb06f11b76b6ea37
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF703 FCGR2A CD68 BCAT1 MERTK	5.50e-05	199	91	5	3e09b3c2e2c57e5248981293020d2434e898e3e1
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid-Microglia\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	FCGR2A SERPINF1 TLR5 CD68 MERTK	5.50e-05	199	91	5	4ddfbcaa8054b69b3398d8c0d5fab8ae94805cb9
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FCGR2A LRP1 CD68 BCAT1 MERTK	5.50e-05	199	91	5	80ed217d28ba1c07facd0e103c25a02658dd848d
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZNF703 FCGR2A CD68 BCAT1 MERTK	5.50e-05	199	91	5	ae6b4b4557c6a9223acdee2a79bc780c5916d38a
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	ZNF703 FCGR2A CD68 BCAT1 MERTK	5.50e-05	199	91	5	4eed28ef8c74d7131eeeabdd732a682d91e034dd
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF703 FCGR2A CD68 BCAT1 MERTK	5.50e-05	199	91	5	f234533254fd82b1ef2041e8405fe201d874018b
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HEXB FCGR2A LRP1 CD68 ITIH5	5.50e-05	199	91	5	8e9862907b15809d083216e7d6a0f435015e5d15
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	FCGR2A SERPINF1 TLR5 CD68 MERTK	5.50e-05	199	91	5	3ba48a4715d5e9387650aa97e0c5d7f7897bf380
ToppCell	tumor_Lung-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	HEXB FCGR2A LRP1 CD68 MERTK	5.63e-05	200	91	5	58ff8db0ecf71daa86f9a38208e0d9b712cac0b5
ToppCell	Transverse-Macrophage-Macrophage\|Transverse / Region, Cell class and subclass	FCGR2A SERPINF1 LRP1 CD68 CTNND1	5.63e-05	200	91	5	17548806ba38008050244151d1216c69ef8a8310
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	FCGR2A SERPINF1 TLR5 CD68 MERTK	5.63e-05	200	91	5	0eccf41edefc3b8b5d0316f57d5ba572949aec2b
Disease	sciatic neuropathy (is_implicated_in)	SERPINF1 LRP1	8.15e-05	5	85	2	DOID:11446 (is_implicated_in)
Disease	melioidosis (is_marker_for)	SERPINF1 TLR5	1.22e-04	6	85	2	DOID:5052 (is_marker_for)
Disease	hemangiopericytoma (is_marker_for)	EPHB4 HEY2	2.91e-04	9	85	2	DOID:264 (is_marker_for)
Disease	chronic fatigue syndrome (is_marker_for)	PRF1 SERPINF1	3.64e-04	10	85	2	DOID:8544 (is_marker_for)
Disease	Polydactyly	TBX3 ALMS1 SC5D TBX5	3.71e-04	117	85	4	C0152427
Disease	obesity (implicated_via_orthology)	KDM3A TCF7 ALMS1 DCHS1 MED12	4.01e-04	215	85	5	DOID:9970 (implicated_via_orthology)
Disease	Systemic lupus erythematosus	FCGR2A TLR5	4.44e-04	11	85	2	cv:C0024141
Disease	congenital diaphragmatic hernia (implicated_via_orthology)	SOX7 LRP1	5.31e-04	12	85	2	DOID:3827 (implicated_via_orthology)
Disease	Libman-Sacks Disease	TCF7 FCGR2A TLR5	6.35e-04	58	85	3	C0242380
Disease	migraine without aura, susceptibility to, 4	LRP1 HPSE2	9.59e-04	16	85	2	MONDO_0011847
Disease	non-Hodgkin lymphoma (is_implicated_in)	FCGR2A PRF1	1.08e-03	17	85	2	DOID:0060060 (is_implicated_in)
Disease	Lupus Erythematosus, Systemic	TCF7 FCGR2A TLR5	1.14e-03	71	85	3	C0024141
Disease	schizophrenia, inflammatory bowel disease	TOX FCGR2A	1.22e-03	18	85	2	EFO_0003767, MONDO_0005090
Disease	Brugada syndrome	HEY2 TBX5	1.36e-03	19	85	2	MONDO_0015263
Disease	left atrial function	MOGAT1 SIX5	1.66e-03	21	85	2	EFO_0004294
Disease	childhood aggressive behaviour measurement	TNRC18 TOX ASB4	2.19e-03	89	85	3	EFO_0007663
Disease	Acute kidney injury	TLR5 SLITRK1	2.36e-03	25	85	2	HP_0001919
Disease	cystic fibrosis (is_implicated_in)	FCGR2A TLR5	2.75e-03	27	85	2	DOID:1485 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
FSVPFHQALNGFHPA	ARMT1	381	Q9H993
AHHSQSFQLLRYPPF	CHTF18	686	Q8WVB6
GTYHNIAFIHPDTPI	PRKAG2	431	Q9UGJ0
SLHLRTSFNSPHLYP	nan	91	Q9N2K0
SLHLRTSFNSPHLYP	nan	91	Q9N2J8
NPRVPHLSSAGQHLY	TFAP2C	26	Q92754
LQNLSLHPGSSALHY	BCAT1	76	P54687
GIISSPHFPSEYHNN	CSMD2	211	Q7Z408
LYQPHRQHTSGLPSA	CACNB3	436	P54284
NHGYVFKPPHQDALL	CACNA2D2	796	Q9NY47
LLNHGAARIYPPQFH	ASB4	311	Q9Y574
FHNGNLIPTHTQPSY	FCGR2A	76	P12318
GSFYQQVLPHSHLPE	ALMS1	1436	Q8TCU4
LTHYADLLPGSPFHV	DPH2	381	Q9BQC3
GFHSLPSYLNHLNNL	ABCA13	4401	Q86UQ4
SPCLNLIPHHLYFAT	AASDH	901	Q4L235
YPNSAAHYHISPGLQ	CECR2	1146	Q9BXF3
FNALPHSAVPEYGHI	ARHGAP11B	51	Q3KRB8
QFLHHTLALYAGQLP	PTPN7	341	P35236
NGVQNYTISPNPHFH	PCDHB18P	111	Q96TA0
YHHRFPQALTSNTPL	LEMD3	871	Q9Y2U8
HPHLLLSFPYGHLSF	CD68	211	P34810
NPLNLIPFYAGSRHH	MSMO1	236	Q15800
SLPHGHHQPFYNVLV	FBXO21	541	O94952
AAAFHHLPAALLQPN	HEY2	186	Q9UBP5
QDLDPSHNYIFGFHP	MOGAT1	96	Q96PD6
HYVLTLSAHDQGSPP	DCHS1	1286	Q96JQ0
NAYDLPRNSHIPGHY	MEGF11	1011	A6BM72
LTFHLPYCGPNQIQH	OR10G7	161	Q8NGN6
LTFHLPYCGPNQIQH	OR10G4	161	Q8NGN3
YFLNIFSHGELPPHC	MAEL	116	Q96JY0
GYQHHLNPEALNLTP	MAFA	121	Q8NHW3
HPLLDQRQPHYSAFG	EPHB4	896	P54760
PAPFQRHHLGFYIAN	ITIH5	816	Q86UX2
DHTPLLSLPHASGYQ	MERTK	46	Q12866
HFLLQYLQPRPGHFI	TRMU	231	O75648
AISAHHNLPLPGYGV	MTO1	391	Q9Y2Z2
LFPGHPHSAYEQAFQ	LRP1	3881	Q07954
NVASSLIQHPGIHYP	ATXN1L	111	P0C7T5
GIFNHSPPHTFLFFL	OR2M2	16	Q96R28
HVFGPLYSHLQPTEL	OR51J1	121	Q9H342
SNLLHAPYHTGDPQL	PGM2L1	11	Q6PCE3
PHHFNASTQPAYLRL	PRF1	201	P14222
SAPNSGPHNRLYHFL	PGLYRP2	56	Q96PD5
VFIPAGAPHQVHNLY	KDM3B	1681	Q7LBC6
LHHPNPGSITHLNYR	MED12	1821	Q93074
HGYNHLVDQNFNPLP	HPSE2	426	Q8WWQ2
GHLHAQGTPPYVINL	GPN1	41	Q9HCN4
PAIPFASYGLHHTSL	SMPD4	261	Q9NXE4
TNHPHIFPYLLVNIG	PANK4	181	Q9NVE7
YSLQAQFLLHHPQPL	TM7SF2	271	O76062
HGLSPQPQTYQSHFR	CCNYL3	306	P0C7X3
LFNLLPGPYSHNFSL	CDHR2	621	Q9BYE9
VFIPAGAPHQVHNLY	KDM3A	1241	Q9Y4C1
LFHNSHVNPLPTGYE	COX6A2	81	Q02221
NYIIANHPHGILSFG	DGAT2L6	101	Q6ZPD8
HLKHGPNAPSLYDNL	GJB4	106	Q9NTQ9
LLPHLPVHFHGSSNF	DNAAF9	611	Q5TEA3
PYVVRLHNFHQLSAP	PRMT5	501	O14744
LSNDNAFLSYHPHPF	IDUA	346	P35475
HPSTLQLPHLGFYVA	ITIH6	1216	Q6UXX5
LPVHYGFHTPASDIQ	HEPACAM2	51	A8MVW5
HLAPENFYISHSPNS	HEXB	71	P07686
NFSYHPSGLSLHLRP	FAM53C	66	Q9NYF3
NGPQDHSHLLYSTIP	CTNND1	86	O60716
LTFHLPYCGPNQIQH	OR10G9	161	Q8NGN4
FNALPHSAVPEYGHI	ARHGAP11A	51	Q6P4F7
PATYHPLHSNLQAHL	SOX7	286	Q9BT81
NHFNLLTTSPVFPHY	TRIM43	381	Q96BQ3
YAPSLHELGHFNIPT	TCAIM	376	Q8N3R3
QFFNGHPLFLHPSQF	TBX3	511	O15119
LPYQHFSAHFTSGPL	TBX5	421	Q99593
AFHSLGAHSPALYPL	FAM178B	376	Q8IXR5
PFPAAHHAFLQDLYL	SIX5	151	Q8N196
SPANYDQAHLHPHLF	SIK3	881	Q9Y2K2
FSAPLFLSHPHFLNA	SCARB1	336	Q8WTV0
PASHLPVGDHLTYSN	FAM13C	466	Q8NE31
QPLTFALQLHDPSGY	PMEL	236	P40967
PFYITHIRAHTNLPG	ERVK-25	556	P63136
SYLHLNHLEPPSSGS	TNRC18	126	O15417
GHLLHPEYLQPLSST	ZNF703	61	Q9H7S9
GLQPAHLTFPLDYHL	SERPINF1	376	P36955
HLTFPLDYHLNQPFI	SERPINF1	381	P36955
PTSQFYHLFLHGNSL	SLITRK1	56	Q96PX8
SHLPPLYLDGHVFAS	PRRC2B	1921	Q5JSZ5
AALQPLPATHAALYH	RPAP1	966	Q9BWH6
AAHLLVPGLQPHTQY	IGSF9	566	Q9P2J2
GVPQLSLYEHFNSPH	TCF7	156	P36402
SSQYPFKHPNLPTHL	nan	161	Q8NA96
FTNLLSVGHQPFHPF	ZNF230	41	Q9UIE0
NHFNLLTTSPVFPHY	TRIM43B	381	A6NCK2
LHPVQFYLTSHGGQL	TRMT10A	136	Q8TBZ6
PFYITHIRAHTNLPG	ERVK-19	561	Q9WJR5
PNLASIYHEHLSQGP	USP34	821	Q70CQ2
ASLGYPLHTPHLISQ	ZNF699	56	Q32M78
HNYLNSLPPGVFSHL	TLR5	511	O60602
HAFHPIDGFLQSLPY	SC5D	166	O75845
PSVFHGPSQAHSALY	TOX	356	O94900
INLTKALGHHNPSYP	PP6455	16	Q8WZ26