Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.79e-105644GO:0052871
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.33e-097644GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.33e-097644GO:0018685
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.99e-0810644GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.99e-0810644GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.99e-0810644GO:0102033
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.71e-0813644GO:0016713
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

9.72e-0724644GO:0008392
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.59e-0627644GO:0008391
GeneOntologyMolecularFunctionaromatase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.66e-0635644GO:0070330
GeneOntologyMolecularFunctioncAMP response element binding protein binding

DAPK3 ATF4 CREB3

6.77e-0612643GO:0008140
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F12 CYP4F11

8.04e-0640644GO:0016709
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

1.01e-052642GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

1.01e-052642GO:0097259
GeneOntologyMolecularFunctionarachidonate binding

CYP4F2 CYP4F12 CYP4F11

1.39e-0515643GO:0050544
GeneOntologyMolecularFunctionicosanoid binding

CYP4F2 CYP4F12 CYP4F11

1.71e-0516643GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F2 CYP4F12 CYP4F11

1.71e-0516643GO:0050543
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.82e-0549644GO:0016712
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4F2 CYP4F12 CYP4F11

9.72e-0528643GO:0036041
GeneOntologyMolecularFunctionmonooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.08e-04115644GO:0004497
GeneOntologyMolecularFunctioncalmodulin binding

MYH14 DAPK2 UBR4 DAPK1 CTH

8.52e-04230645GO:0005516
GeneOntologyMolecularFunctionleucine zipper domain binding

DAPK3 ATF4

8.98e-0414642GO:0043522
GeneOntologyMolecularFunctionfatty acid binding

CYP4F2 CYP4F12 CYP4F11

1.41e-0369643GO:0005504
GeneOntologyMolecularFunctionheme binding

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.51e-03154644GO:0020037
GeneOntologyMolecularFunctiontetrapyrrole binding

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.90e-03164644GO:0046906
GeneOntologyMolecularFunctioniron ion binding

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.99e-03166644GO:0005506
GeneOntologyMolecularFunctionLRR domain binding

DAPK3 ATF4

2.24e-0322642GO:0030275
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.48e-03194644GO:0016705
GeneOntologyMolecularFunctionlipid binding

EPHX1 ICA1 PDIA2 ZFYVE26 CYP4F2 CYP4F12 DENND1C CYP4F11 SOAT2

4.08e-03988649GO:0008289
GeneOntologyMolecularFunctionprotein methyltransferase activity

ARMT1 FAM98A PRMT7

4.42e-03103643GO:0008276
GeneOntologyMolecularFunctionadenylyltransferase activity

SELENOO TUT1

4.43e-0331642GO:0070566
GeneOntologyMolecularFunctionmonocarboxylic acid binding

CYP4F2 CYP4F12 CYP4F11

4.92e-03107643GO:0033293
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.18e-096634GO:0036101
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.75e-097634GO:0036102
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.48e-098634GO:0036100
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.57e-0811634GO:1901523
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F12 CYP4F11

2.72e-083633GO:0042361
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.84e-0812634GO:0042758
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F12 CYP4F11

1.08e-074633GO:0009233
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F12 CYP4F11

1.08e-074633GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F12 CYP4F11

1.08e-074633GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F12 CYP4F11

1.08e-074633GO:0042377
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F2 CYP4F12 CYP4F11

5.40e-076633GO:1905344
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F2 CYP4F12 CYP4F11

5.40e-076633GO:0062232
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.55e-0722634GO:1901569
GeneOntologyBiologicalProcessarachidonate metabolic process

EPHX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.03e-0668635GO:0019369
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

TKFC CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.89e-0673635GO:1901616
GeneOntologyBiologicalProcessvitamin K metabolic process

CYP4F2 CYP4F12 CYP4F11

4.40e-0611633GO:0042373
GeneOntologyBiologicalProcessfat-soluble vitamin catabolic process

CYP4F2 CYP4F12 CYP4F11

5.86e-0612633GO:0042363
GeneOntologyBiologicalProcessleukotriene metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

7.35e-0641634GO:0006691
GeneOntologyBiologicalProcessomega-hydroxylase P450 pathway

CYP4F2 CYP4F12 CYP4F11

9.65e-0614633GO:0097267
GeneOntologyBiologicalProcessvitamin catabolic process

CYP4F2 CYP4F12 CYP4F11

2.14e-0518633GO:0009111
GeneOntologyBiologicalProcessorganic hydroxy compound metabolic process

EPHX1 TKFC INPP5B SREBF2 CYP4F2 CYP4F3 CYP4F12 CYP4F11 LEPR SOAT2

2.27e-056416310GO:1901615
GeneOntologyBiologicalProcessketone catabolic process

CYP4F2 CYP4F12 CYP4F11

3.47e-0521633GO:0042182
GeneOntologyBiologicalProcesslong-chain fatty acid metabolic process

EPHX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.85e-05124635GO:0001676
GeneOntologyBiologicalProcessunsaturated fatty acid metabolic process

EPHX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.48e-05128635GO:0033559
GeneOntologyBiologicalProcessicosanoid metabolic process

EPHX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

7.35e-05142635GO:0006690
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.16e-0482634GO:1901568
GeneOntologyBiologicalProcessvitamin E metabolic process

CYP4F2 CYP4F12

1.37e-046632GO:0042360
GeneOntologyBiologicalProcessolefinic compound metabolic process

EPHX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.23e-04180635GO:0120254
GeneOntologyBiologicalProcesscellular catabolic process

CHMP7 DAPK2 UBR4 SREBF2 DAPK1 DAPK3 ZFYVE26 CYP4F2 CYP4F3 CYP4F12 CYP4F11 LEPR

3.57e-0412536312GO:0044248
GeneOntologyBiologicalProcesscellular response to topologically incorrect protein

UBR4 CTH ATF4 CREB3

4.38e-04116634GO:0035967
GeneOntologyBiologicalProcessfatty acid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.38e-04116634GO:0009062
GeneOntologyBiologicalProcessfat-soluble vitamin metabolic process

CYP4F2 CYP4F12 CYP4F11

5.09e-0451633GO:0006775
GeneOntologyBiologicalProcessprocess utilizing autophagic mechanism

CHMP7 DAPK2 UBR4 SREBF2 DAPK1 DAPK3 ZFYVE26 LEPR

7.83e-04650638GO:0061919
GeneOntologyBiologicalProcessautophagy

CHMP7 DAPK2 UBR4 SREBF2 DAPK1 DAPK3 ZFYVE26 LEPR

7.83e-04650638GO:0006914
GeneOntologyBiologicalProcessxenobiotic metabolic process

EPHX1 ABCC4 CYP4F2 CYP4F12

9.12e-04141634GO:0006805
MousePhenoabnormal pancreatic beta cell mass

COL5A3 ATF4 LEPR SERTAD1

1.80e-0547474MP:0009112
DomainDAPK1

DAPK2 DAPK1 DAPK3

3.66e-083633IPR020676
DomainCyt_P450_E_grp-I

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.58e-0545634IPR002401
DomainCyt_P450_CS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.04e-0553634IPR017972
DomainCYTOCHROME_P450

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.06e-0557634PS00086
Domain-

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.35e-05586341.10.630.10
Domainp450

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.35e-0558634PF00067
DomainCyt_P450

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.97e-0560634IPR001128
DomainHempt_rcpt_S_F1_CS

IL4R LEPR

3.97e-049632IPR003531
DomainDUF1605

DHX15 DQX1

1.47e-0317632IPR011709
DomainOB_NTP_bind

DHX15 DQX1

1.47e-0317632PF07717
DomainHA2

DHX15 DQX1

1.65e-0318632SM00847
DomainHA2

DHX15 DQX1

1.65e-0318632PF04408
DomainHelicase-assoc_dom

DHX15 DQX1

1.65e-0318632IPR007502
DomainFN3

PTPRF MYOM3 IL4R LEPR

3.52e-03185634SM00060
Domain-

NRXN2 COL5A3 CLSTN1

4.06e-03956332.60.120.200
DomainFN3

PTPRF MYOM3 IL4R LEPR

4.56e-03199634PS50853
DomainFN3_dom

PTPRF MYOM3 IL4R LEPR

5.42e-03209634IPR003961
DomainHelicase_C

DHX15 DQX1 ASCC3

5.81e-03108633IPR001650
DomainbZIP_1

ATF4 CREB3

5.86e-0334632PF00170
DomainZnf_FYVE-rel

ZFYVE26 RIMS1

5.86e-0334632IPR017455
DomainHELICASE_CTER

DHX15 DQX1 ASCC3

5.96e-03109633PS51194
DomainHELICASE_ATP_BIND_1

DHX15 DQX1 ASCC3

5.96e-03109633PS51192
DomainDEXDc

DHX15 DQX1 ASCC3

5.96e-03109633SM00487
DomainHelicase_ATP-bd

DHX15 DQX1 ASCC3

6.11e-03110633IPR014001
DomainConA-like_dom

RNF123 NRXN2 COL5A3 CLSTN1

6.38e-03219634IPR013320
DomainZnf_FYVE

ZFYVE26 RIMS1

7.28e-0338632IPR000306
DomainZF_FYVE

ZFYVE26 RIMS1

8.04e-0340632PS50178
DomainLaminin_G_2

NRXN2 COL5A3

8.04e-0340632PF02210
DomainLamG

NRXN2 COL5A3

9.67e-0344632SM00282
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

8.62e-0812534M27129
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

8.62e-0812534MM14845
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.73e-0714534MM15842
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.36e-0715534M27126
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.24e-0718534MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.24e-0718534MM14841
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.12e-0625534MM14858
PathwayREACTOME_CASPASE_ACTIVATION_VIA_DEPENDENCE_RECEPTORS_IN_THE_ABSENCE_OF_LIGAND

DAPK2 DAPK1 DAPK3

5.91e-0610533M866
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.72e-0633534MM15918
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.72e-0633534MM15963
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP4F2 CYP4F12 CYP4F11

8.11e-0611533MM14863
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F11

1.08e-0512533M27128
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

EPHX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.30e-05104535M738
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

EPHX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.50e-05105535MM14842
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F3 CYP4F11

6.36e-0521533M27137
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F12 CYP4F11

7.93e-0561534MM14861
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4F2 CYP4F3 CYP4F12 CYP4F11

8.45e-0562534M39653
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F2 CYP4F3 CYP4F12 CYP4F11

9.57e-0564534M5650
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.08e-0466534MM14839
PathwayREACTOME_CASPASE_ACTIVATION_VIA_EXTRINSIC_APOPTOTIC_SIGNALLING_PATHWAY

DAPK2 DAPK1 DAPK3

1.23e-0426533M27434
PathwayWP_BLADDER_CANCER

DAPK2 DAPK1 DAPK3

4.49e-0440533M39523
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY

CYP4F2 CYP4F12

4.91e-049532M39819
PathwayKEGG_BLADDER_CANCER

DAPK2 DAPK1 DAPK3

5.19e-0442533M19096
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

EPHX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.05e-04183535M39588
PathwayWP_TRYPTOPHAN_METABOLISM

CYP4F2 CYP4F12 CYP4F11

7.70e-0448533MM15902
PathwayKEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_CREB_MEDIATED_TRANSCRIPTION

ATF4 CREB3

1.05e-0313532M47595
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_CREB_MEDIATED_TRANSCRIPTION

ATF4 CREB3

1.05e-0313532M47674
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

EPHX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.35e-03219535MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

EPHX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.38e-03220535M10320
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F11

1.41e-0359533M27140
PathwayKEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY

ATF4 CREB3

1.61e-0316532M47551
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKACA_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

ATF4 CREB3

1.82e-0317532M47514
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

ATF4 CREB3

2.04e-0318532M47516
PathwayWP_CHOLESTASIS

EPHX1 ABCC4

2.28e-0319532M45520
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PDE11A_PDE8B_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

ATF4 CREB3

2.52e-0320532M47517
PathwayKEGG_MEDICUS_REFERENCE_ACH_CHRN_RAS_ERK_SIGNALING_PATHWAY

ATF4 CREB3

2.78e-0321532M47792
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.26e-11467418065749
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.88e-1066749068972
Pubmed

The death-associated protein kinases: structure, function, and beyond.

DAPK2 DAPK1 DAPK3

6.83e-09367316756490
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F2 CYP4F12 CYP4F11

2.73e-08467322665481
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F2 CYP4F12 CYP4F11

2.73e-08467311185557
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F2 CYP4F12 CYP4F11

6.81e-08567322969154
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F2 CYP4F12 CYP4F11

6.81e-08567321466787
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

CYP4F2 CYP4F12 CYP4F11

2.38e-07767322160543
Pubmed

Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

CYP4F2 CYP4F11

3.66e-06267224138531
Pubmed

Expression of CYP4F2 in human liver and kidney: assessment using targeted peptide antibodies.

CYP4F2 CYP4F12

3.66e-06267218662666
Pubmed

Ser289 phosphorylation activates both DAPK1 and DAPK2 but in response to different intracellular signaling pathways.

DAPK2 DAPK1

3.66e-06267231116076
Pubmed

Sodium butyrate-induced DAPK-mediated apoptosis in human gastric cancer cells.

DAPK2 DAPK1

3.66e-06267222160140
Pubmed

Expression and physiological function of CYP4F subfamily in human eosinophils.

CYP4F3 CYP4F12

3.66e-06267217980168
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

3.66e-0626728026587
Pubmed

Attenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2.

DAPK2 DAPK1

3.66e-06267218535204
Pubmed

Integrated stress response modulates cellular redox state via induction of cystathionine γ-lyase: cross-talk between integrated stress response and thiol metabolism.

CTH ATF4

3.66e-06267222215680
Pubmed

ZIP kinase, a novel serine/threonine kinase which mediates apoptosis.

DAPK3 ATF4

3.66e-0626729488481
Pubmed

New modularity of DAP-kinases: alternative splicing of the DRP-1 gene produces a ZIPk-like isoform.

DAPK2 ATF4

3.66e-06267221408167
Pubmed

Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

CYP4F3 CYP4F11

3.66e-06267215364545
Pubmed

Regulation of human cytochrome P450 4F2 expression by sterol regulatory element-binding protein and lovastatin.

SREBF2 CYP4F2

3.66e-06267217142457
Pubmed

Golgi stress response reprograms cysteine metabolism to confer cytoprotection in Huntington's disease.

CTH ATF4

3.66e-06267229317536
Pubmed

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.05e-057067415128046
Pubmed

Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.

CYP4F2 CYP4F3

1.10e-05367215145985
Pubmed

Diabetes and insulin in regulation of brain cholesterol metabolism.

SREBF2 LEPR

1.10e-05367221109190
Pubmed

Advanced glycation end products promote meniscal calcification by activating the mTOR-ATF4 positive feedback loop.

ATF4 LEPR

1.10e-05367238424194
Pubmed

MicroRNA-214 suppresses gluconeogenesis by targeting activating transcriptional factor 4.

ATF4 LEPR

1.10e-05367225657009
Pubmed

DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death.

DAPK2 DAPK1

1.10e-05367211980920
Pubmed

Lithium response and genetic variation in the CREB family of genes.

ATF4 CREB3

1.10e-05367218189280
Pubmed

Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.

EPHX1 CYP4F2 CYP4F12 CYP4F11

1.45e-057667422323595
Pubmed

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis.

DAPK2 DAPK1

2.19e-05467210629061
Pubmed

Impact of genetic factors (VKORC1, CYP2C9, CYP4F2 and EPHX1) on the anticoagulation response to fluindione.

EPHX1 CYP4F2

2.19e-05467221883387
Pubmed

DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expression.

DAPK1 DAPK3

3.64e-05567218995835
Pubmed

BTG1 ameliorates liver steatosis by decreasing stearoyl-CoA desaturase 1 (SCD1) abundance and altering hepatic lipid metabolism.

ATF4 LEPR

3.64e-05567227188441
Pubmed

ZIP kinase triggers apoptosis from nuclear PML oncogenic domains.

DAPK3 ATF4

3.64e-05567212917339
Pubmed

Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism.

CYP4F2 CYP4F3

3.64e-05567218577768
Pubmed

The role of KLF2 in regulating hepatic lipogenesis and blood cholesterol homeostasis via the SCAP/SREBP pathway.

SREBF2 LEPR

5.46e-05667237949368
Pubmed

Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6.

SREBF2 LEPR

5.46e-05667223881913
Pubmed

Presynaptic α2δ-2 Calcium Channel Subunits Regulate Postsynaptic GABAA Receptor Abundance and Axonal Wiring.

NRXN2 CACNA2D2

5.46e-05667230683685
Pubmed

Unfolded Protein Response (UPR) is activated during normal lens development.

PDIA2 ATF4

7.63e-05767221044701
Pubmed

Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages.

DAPK1 DAPK3

7.63e-05767223071094
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ESRP2 RNF123 DQX1 ICA1 UBR4 MYOM3 PKHD1 ZBTB11

8.40e-0573667829676528
Pubmed

PTEN identified as important risk factor of chronic obstructive pulmonary disease.

EPHX1 ABCC4 CTH IL4R LEPR SOAT2

8.53e-0537467619625176
Pubmed

Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.

CYP4F2 CYP4F12 CYP4F11

8.55e-054467312745259
Pubmed

Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.

EPHX1 ABCC4 CTH IL4R LEPR SOAT2

9.44e-0538167618676680
Pubmed

Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.

EPHX1 ABCC4 CTH IL4R LEPR SOAT2

9.58e-0538267619170196
Pubmed

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.

CYP4F2 CYP4F12 CYP4F11

9.78e-054667325209997
Pubmed

ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization.

SREBF2 SOAT2

1.02e-0486729756919
Pubmed

Spatacsin regulates directionality of lysosome trafficking by promoting the degradation of its partner AP5Z1.

UBR4 ZFYVE26

1.02e-04867237871017
Pubmed

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.

PTPRF NRXN2

1.02e-04867237591863
Pubmed

Genetic factors (VKORC1, CYP2C9, EPHX1, and CYP4F2) are predictor variables for warfarin response in very elderly, frail inpatients.

EPHX1 CYP4F2

1.02e-04867219794411
Pubmed

Roles of CHOP/GADD153 in endoplasmic reticulum stress.

DAPK3 ATF4

1.02e-04867214685163
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

ICA1 CALCOCO1 CCAR2 MLLT11 CPLANE1 DDB1 SERTAD1

1.02e-0456067721653829
Pubmed

Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.

UBR4 DDB1

1.30e-04967217855541
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

DHX15 ARMT1 CLTCL1 MYH14 UBR4 DAPK1 COL5A3 DDB1

1.58e-0480767830575818
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

EPHX1 PARP10 UBR4 MLLT11 ASCC3 EME2 PRMT7

1.62e-0460467738803224
Pubmed

Genetic susceptibility to distinct bladder cancer subphenotypes.

EPHX1 ABCC4 CTH IL4R LEPR SOAT2

1.62e-0442167619692168
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

DHX15 EPHX1 FAM98A ASCC3 DDB1

1.71e-0426867533024031
Pubmed

A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study.

ABCC4 PKHD1

1.99e-041167217903305
Pubmed

Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1.

DAPK1 DAPK3

1.99e-041167215001356
Pubmed

CRL4(WDR23)-Mediated SLBP Ubiquitylation Ensures Histone Supply during DNA Replication.

DHX15 DDB1

1.99e-041167227203182
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

DHX15 RBM33 IFT172 UBR4 CCAR2 ASCC3 DDB1

2.27e-0463867733239621
Pubmed

HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1.

UBR4 DDB1

2.38e-041267217360488
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DHX15 MYH14 UBR4 CCAR2 ASCC3 ZBTB11 DDB1

2.61e-0465367722586326
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ESRP2 TKFC CLTCL1 PTPRF UBR4 MYOM3 ZFYVE26 IL4R CREB3

2.61e-04110567935748872
Pubmed

Alternative splice variants encoding unstable protein domains exist in the human brain.

PTPRF NRXN2

2.81e-041367215491607
Pubmed

Genetic determinants of warfarin dosing in the Han-Chinese population.

EPHX1 CYP4F2

2.81e-041367219958090
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

DHX15 MYH14 ZBTB47 CCAR2 FAM98A DDB1

3.82e-0449467626831064
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

PTPRF GHDC UBR4 SREBF2 CTH ASCC3 CLSTN1 COG8

4.47e-0494267831073040
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

EPHX1 ABCC4 CYP4F2 CYP4F3

5.36e-0419367419343046
Pubmed

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.

UBR4 CCAR2 DDB1

5.82e-048467329563501
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

CLTCL1 MYH14 PKHD1 ASCC3

6.36e-0420267424639526
Pubmed

A cohesin-RAD21 interactome.

RNF123 DAPK3 CCAR2 DDB1

7.10e-0420867422145905
Pubmed

Heritability and genetic association analysis of cognition in the Diabetes Heart Study.

ICA1 DAPK1

7.50e-042167224684796
Pubmed

Noncoding RNA MaIL1 is an integral component of the TLR4-TRIF pathway.

ELMO3 CCAR2

8.24e-042267232241891
Pubmed

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals.

ATF4 CREB3

8.24e-042267228566324
Pubmed

Comprehensive identification of human bZIP interactions with coiled-coil arrays.

ATF4 CREB3

9.01e-042367212805554
Pubmed

Functional proteomics mapping of a human signaling pathway.

RNF123 PTPRF UBR4 ASCC3 ZBTB11 DDB1

9.74e-0459167615231748
Pubmed

BTG4 is a meiotic cell cycle-coupled maternal-zygotic-transition licensing factor in oocytes.

DDB1 SERTAD1

9.82e-042467227065194
Pubmed

Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth.

SREBF2 ATF4

1.07e-032567230604742
Pubmed

Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.

EPHX1 LEPR

1.07e-032567218992263
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

CLTCL1 MYH14 CLSTN1 DDB1

1.12e-0323567430258100
Pubmed

CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.

CCAR2 MLLT11 DDB1

1.21e-0310867330166453
Pubmed

Disruption of Trip11 in cranial neural crest cells is associated with increased ER and Golgi stress contributing to skull defects in mice.

CTH ATF4

1.24e-032767235147267
Pubmed

Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.

EPHX1 CYP4F11

1.34e-032867220689807
Pubmed

SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis.

CCAR2 DDB1

1.34e-032867234163012
Pubmed

Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies.

EPHX1 TKFC MYH14 CCAR2

1.38e-0324967430097533
Pubmed

Large-scale cDNA transfection screening for genes related to cancer development and progression.

ESRP2 RNF123 MYH14

1.41e-0311467315498874
Pubmed

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.

MYH14 UBR4 CCAR2 DDB1

1.46e-0325367429911972
Pubmed

The unfolded protein response: integrating stress signals through the stress sensor IRE1α.

PDIA2 ATF4

1.64e-033167222013210
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DHX15 NRXN2 MYH14 CALCOCO1 DAPK1 DAPK3 FAM98A RIMS1 DDB1

1.64e-03143167937142655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CLTCL1 MYH14 UBR4 PKHD1 PDIA2 CCAR2 FAM98A RIMS1 ZBTB11

1.73e-03144267935575683
Pubmed

The AAA-ATPase ATAD1 and its partners promote degradation of desmin intermediate filaments in muscle.

RNF123 UBR4

1.75e-033267236278411
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

DHX15 RNF123 TKFC MYH14 UBR4 CCAR2 CTH TUT1 DDB1

1.84e-03145567922863883
Pubmed

Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays.

ATF4 CREB3

1.86e-033367220102225
Cytoband16q22.1

ESRP2 ELMO3 PRMT7 COG8

2.13e-0511067416q22.1
CytobandEnsembl 112 genes in cytogenetic band chr16q22

ESRP2 ELMO3 PRMT7 COG8

1.54e-04183674chr16q22
CytobandEnsembl 112 genes in cytogenetic band chr19p13

COL5A3 DAPK3 CYP4F2 CYP4F3 CYP4F12 DENND1C CYP4F11

1.63e-04797677chr19p13
Cytoband1p34

PTPRF INPP5B

1.01e-03326721p34
Cytoband2p13.1

DQX1 C2orf81

1.14e-03346722p13.1
Cytoband11q12.2

TKFC TUT1

1.50e-033967211q12.2
Cytoband19p13.1

CYP4F12 CYP4F11

2.27e-034867219p13.1
Cytoband12q13.13

CALCOCO1 SOAT2

4.36e-036767212q13.13
GeneFamilyAnkyrin repeat domain containing|Death associated protein kinases

DAPK2 DAPK1 DAPK3

1.34e-0754431021
GeneFamilyCytochrome P450 family 4

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.70e-06364441003
CoexpressionCHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN

EPHX1 SELENOO CYP4F2 CYP4F3 CTH CYP4F11

6.59e-06179676M16932
CoexpressionSAENZ_DETOX_PATHWAY_AND_CARCINOGENESIS_DN

CYP4F2 CYP4F12 CYP4F11

1.76e-0520673MM1104
CoexpressionMIKKELSEN_MEF_LCP_WITH_H3K4ME3

RNF123 DAPK3 CYP4F3 IFI35 SOAT2

1.95e-05128675M1966
CoexpressionONDER_CDH1_TARGETS_1_UP

EPHX1 CYP4F3 CTH CYP4F11 LEPR

2.89e-05139675M18757
CoexpressionWOO_LIVER_CANCER_RECURRENCE_DN

EPHX1 CYP4F2 CYP4F3 CYP4F12

4.82e-0578674M9911
CoexpressionMIKKELSEN_MCV6_LCP_WITH_H3K4ME3

RNF123 DQX1 DAPK3 CYP4F3 IFI35

6.01e-05162675M1960
CoexpressionMIKKELSEN_IPS_LCP_WITH_H3K4ME3

DQX1 DAPK3 CYP4F3 IFI35 SOAT2

8.66e-05175675M1975
CoexpressionPARENT_MTOR_SIGNALING_UP

RNF123 CALCOCO1 SREBF2 CYP4F2 CYP4F12 CTH CLSTN1 CYP4F11

9.70e-05567678M16909
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC26A8 ABCC4 ICA1 SREBF2 RIMS1 ASCC3

2.69e-071766763bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTPRF MYH14 DAPK2 ICA1 PKHD1 DAPK1

4.63e-07193676a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF MYH14 DAPK2 PKHD1 DAPK1

7.87e-06181675b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1-AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPHX1 PTPRF MYH14 DAPK2 PKHD1

8.08e-06182675cc79e0cc21e2fdc4ef77f052818d27b9f707aec1
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF MYH14 DAPK2 PKHD1 DAPK1

8.52e-0618467542ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellfacs-BAT-Fat-24m-Epithelial-Epcam+|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELMO3 PTPRF MYH14 MYOM3 CTH

8.98e-06186675b18d7398279a2d42414318aeb70514fd402f5a0a
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESRP2 ELMO3 PTPRF MYH14 PKHD1

8.98e-061866753c4994a1a7db06a61da8170e45e06aaef7896592
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF MYH14 DAPK2 PKHD1 DAPK1

8.98e-061866754e94158db52df41d71e67b02b9895a358eebee0f
ToppCellfacs-Lung-EPCAM-24m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESRP2 ELMO3 PTPRF MYH14 PKHD1

8.98e-06186675a583d6fc0f1e729f6e9fd18d7b49d6eab9ca32b9
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF MYH14 DAPK2 PKHD1 DAPK1

8.98e-061866753aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF MYH14 DAPK2 PKHD1 DAPK1

9.21e-0618767558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellPCW_05-06-Epithelial-Epithelial_airway|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ESRP2 PTPRF MYH14 ICA1 PKHD1

1.07e-05193675af6ec2c2ba92aef3e41531c3c7215b3300437bd9
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ESRP2 PTPRF MYH14 ICA1 PKHD1

1.10e-05194675c5ef4ff73b4e51530656002e3a2fb7264cdf533d
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ESRP2 PTPRF MYH14 ICA1 PKHD1

1.10e-05194675b19e16a76d7342ff9a665d19c9151652916f17d4
ToppCellPCW_05-06-Epithelial|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ESRP2 PTPRF MYH14 ICA1 PKHD1

1.10e-0519467547a1369c22fcbfe00b08376eb610a61c355548db
ToppCellCOVID_vent-Myeloid-Monocytic-Developing_Neutrophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

CLTCL1 DAPK2 ICA1 CYP4F2 CYP4F3

1.13e-05195675de23409b1b4146b8ae286850b829ec8dceed0117
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

EPHX1 ABCC4 PTPRF MYH14 DAPK1

1.19e-0519767544a59dfb889577b3160a5b13ada1276771a00241
ToppCellControl_saline-Epithelial_alveolar-AT_2|Control_saline / Treatment groups by lineage, cell group, cell type

EPHX1 ABCC4 PTPRF MYH14 DAPK1

1.19e-05197675b8f62fcd6eb8f47b3cc41f616126f82c68a36e87
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PTPRF MYH14 DAPK2 PKHD1 DAPK1

1.19e-051976753d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PTPRF MYH14 DAPK2 PKHD1 DAPK1

1.21e-05198675b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCellControl_saline-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|Control_saline / Treatment groups by lineage, cell group, cell type

EPHX1 ABCC4 PTPRF MYH14 DAPK1

1.21e-05198675030ef63e2fc5b3d601c1a48462d797aa19ee7ff5
ToppCellControl_saline-Epithelial_alveolar-AT_1-2_Progenitor-Progenitor_AT1-AT2|Control_saline / Treatment groups by lineage, cell group, cell type

EPHX1 PTPRF MYH14 DAPK2 DAPK1

1.21e-05198675827aa9d919bf6d670961e5501e17d351676127e3
ToppCellControl_saline-Epithelial_alveolar-AT_1|Control_saline / Treatment groups by lineage, cell group, cell type

PTPRF MYH14 DAPK2 PKHD1 DAPK1

1.21e-051986759b161285df7a4e51618f3517cfc5b8221ba55786
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

PTPRF MYH14 DAPK2 PKHD1 DAPK1

1.21e-0519867585f424cd9bb3117c9e322031024aabb87696ce47
ToppCellControl_saline-Epithelial_alveolar|Control_saline / Treatment groups by lineage, cell group, cell type

EPHX1 PTPRF MYH14 DAPK2 DAPK1

1.21e-05198675532b7ef4ad46fe35ad2c6bdf89f70a17f1a2e2e2
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PTPRF MYH14 DAPK2 PKHD1 DAPK1

1.24e-05199675a270630626df614f8605abddb7dee7c4d74f6149
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA2D2 MYH14 DAPK2 SREBF2 DAPK1

1.24e-051996755cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PTPRF MYH14 DAPK2 PKHD1 DAPK1

1.24e-05199675d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PTPRF MYH14 DAPK2 PKHD1 DAPK1

1.24e-051996751c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

EPHX1 PTPRF MYH14 DAPK2 DAPK1

1.24e-051996758c9ec5f05b79cf5ae1bf7aade603c171fb0226a9
ToppCellBronchial_Biopsy-Epithelial|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

EPHX1 PTPRF MYH14 IFT172 CLSTN1

1.24e-05199675ef5d8917c8d011184830a0b8197afc6266707b37
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

EPHX1 PTPRF MYH14 CPLANE1 CLSTN1

1.27e-0520067597f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PTPRF MYH14 DAPK2 PKHD1 DAPK1

1.27e-05200675ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPHX1 PTPRF MYH14 CPLANE1 CLSTN1

1.27e-05200675ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PTPRF MYH14 DAPK2 PKHD1 DAPK1

1.27e-052006758683445ad5b70748c4a1f12eb77d47623085147e
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 MYH14 DAPK2 DAPK1

4.43e-051306746434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC26A8 PDIA2 DAPK1 RIMS1

6.77e-05145674b961b69befb15ff6f58635e0d4bda88ea732a346
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH14 DAPK2 PKHD1 TUT1

9.22e-051576744766f7d545bf2d775390589460677519cb92f4d5
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DAPK2 EME2 LEPR SOAT2

9.22e-051576741f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLTCL1 PTPRF COL5A3 RIMS1

9.22e-05157674f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

PTPRF PDIA2 RIMS1 CYP4F11

1.14e-041666744d63c758d46e73311b864148c646bf081498dee7
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

PTPRF PDIA2 RIMS1 CYP4F11

1.14e-041666744160ccf9291072a6e2782f9ad141bc9a9747f3ad
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

RNF123 PTPRF IFT172 CPLANE1

1.14e-0416667432d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ESRP2 PDIA2 RIMS1 CYP4F11

1.20e-04168674e870d2e69316406f45112ed0bf324b24f902a99e
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ESRP2 PDIA2 RIMS1 CYP4F11

1.20e-04168674403aba73a0f9ffb32252288d075fad8a588ca440
ToppCellfacs-Heart-LV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN2 IFT172 COL5A3 LEPR

1.22e-04169674849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC26A8 PTPRF MYH14 DAPK2

1.40e-04175674442f261a3b2c4d2523f7d4089178f8c79cac2f0f
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC26A8 PTPRF MYH14 DAPK2

1.40e-0417567435fb7735dd3355476fe60404833cb60bd066bcf1
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN2 IFT172 COL5A3 LEPR

1.43e-04176674f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN2 IFT172 COL5A3 LEPR

1.43e-04176674fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH14 DAPK2 PKHD1 DAPK1

1.46e-041776749af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellControl-Epithelial_alveolar-AT_1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH14 DAPK2 PKHD1 DAPK1

1.49e-04178674aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCC4 MYH14 DAPK2 DAPK1

1.49e-04178674f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF MYH14 DAPK2 PKHD1

1.53e-0417967404ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TKFC PTPRF NRXN2 CALCOCO1

1.56e-04180674bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellfacs-Marrow-B-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TKFC PTPRF NRXN2 CALCOCO1

1.56e-04180674839defb40f7cfb2711e9025194de636533f51bcd
ToppCellICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, Lineage and Cell Type

PTPRF DAPK2 CTH CPLANE1

1.56e-04180674be665e801512f6aaf6b3ecb26153bbdeb24619ac
ToppCellfacs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TKFC PTPRF NRXN2 CALCOCO1

1.56e-0418067482965ed1b72a1873c24dd4553d39681596057316
ToppCelldroplet-Lung-nan-21m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRF MYH14 MYOM3 ITPRID1

1.63e-0418267440539ade8c3cd12b61f1cd0d493828e58282796b
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ESRP2 PTPRF MYH14 PKHD1

1.66e-04183674c5b10571599dc26476170b54b53f09c23e6b3117
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF MYH14 DAPK2 PKHD1

1.66e-04183674ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF MYH14 DAPK2 PKHD1

1.66e-04183674274483009b309289e4cb84beedf6806430db6ff6
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF MYH14 DAPK2 PKHD1

1.70e-04184674cdf6f1c6cce97a7effa0c55959652e2c0b6992b3
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPHX1 MYH14 DAPK2 DAPK1

1.70e-0418467451e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ESRP2 MYH14 ICA1 PKHD1

1.70e-04184674fa4915b0498f3069fd5ef497286445528f75187e
ToppCellPND01-03-samps-Epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ESRP2 PTPRF MYH14 DAPK2

1.73e-041856742b854df79cfe2cb4d2f9c2938a066e0aa3649325
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF MYH14 DAPK2 PKHD1

1.73e-041856743bef59cc0aa939d2a7e52f0f6c61bc00528fe50b
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ESRP2 ELMO3 PKHD1 COG8

1.73e-04185674636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPHX1 MYH14 DAPK2 DAPK1

1.73e-041856740d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH14 DAPK2 PKHD1 DAPK1

1.73e-041856743937e026add96a396122139daf8011cfbc60e75c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

PTPRF MYH14 DAPK2 CPLANE1

1.73e-0418567432b4e68e551d435a732f253f6ad83408c759a642
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF MYH14 DAPK2 PKHD1

1.73e-04185674c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ABCC4 MYH14 DAPK2 DAPK1

1.81e-0418767481cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PTPRF DAPK2 ICA1 PKHD1

1.84e-041886740d86044bc340e3efb90d0022dd299873639d831c
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 PTPRF MYH14 DAPK2

1.84e-0418867443a0508d2524a5b310e89e9422843dcaab999bc3
ToppCellfacs-Lung-EPCAM-24m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESRP2 PTPRF MYH14 C2orf81

1.84e-04188674c2ef270f691d367b1621d48f0771267cefe1630d
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PTPRF MYH14 ICA1 PKHD1

1.88e-041896747659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

EPHX1 ESRP2 PTPRF CACNA2D2

1.88e-041896742d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ELMO3 PTPRF MYH14 ITPRID1

1.88e-04189674ee15b4fb3a1cfda80bcf210a23f04f242594015e
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ELMO3 PTPRF MYH14 ITPRID1

1.88e-04189674dc6f6fae84347d145bea71b49eaeeb3028e9c4ae
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYH14 DAPK2 PKHD1 DAPK1

1.92e-041906748aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRXN2 DAPK2 CCAR2 C2orf81

1.92e-04190674a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ESRP2 PTPRF ICA1 PKHD1

1.92e-04190674c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

DHX15 CHMP7 RNF123 TKFC

1.92e-041906742434b8ad2976eab7d9147012c28454ab29670709
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRXN2 DAPK2 CCAR2 C2orf81

1.92e-0419067457c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRXN2 DAPK2 CCAR2 C2orf81

1.92e-04190674f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ESRP2 MYH14 ICA1 PKHD1

1.96e-0419167472dbd2e0fabfca8d6f604df35277d3574739a0b3
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

MYH14 DAPK2 PKHD1 DAPK1

1.96e-04191674d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellcontrol-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ABCC4 GHDC CACNA2D2 ZFYVE26

1.96e-04191674afebdc59a1f884ce3f2f5fe040e16b0e95e4e7c5
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PTPRF MYH14 ICA1 PKHD1

1.96e-0419167460ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ESRP2 MYH14 ICA1 PKHD1

1.96e-0419167405731ece7867659c662f952812805f947032fe10
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ESRP2 ABCC4 CACNA2D2 PKHD1

2.00e-04192674fa2420d6117d4800f60ef6a24bcf8bf54593cd1f
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor-epi-tip_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ESRP2 ABCC4 CACNA2D2 PKHD1

2.00e-0419267487b60014202633a4f6d19b09a5dd9276c2edecfb
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

PTPRF CACNA2D2 MYH14 DAPK2

2.00e-04192674efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

PTPRF CACNA2D2 MYH14 DAPK2

2.00e-04192674499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell11.5-Airway-Epithelial-Bud_tip_adjacent|Airway / Age, Tissue, Lineage and Cell class

ESRP2 PTPRF ICA1 PKHD1

2.00e-04192674fbb34a959b9bd9cb72a5195a07f4653a957e4ca8
ToppCellfacs-Lung-24m-Epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESRP2 PTPRF MYH14 C2orf81

2.00e-04192674ebfd8209a7353fbccb8ca7ade14b4f25822cebd2
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SREBF2 DAPK3 ZBTB11 SERTAD1

2.00e-041926743f925a80b5e2b0577d573e88598a2984a5f6a789
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ESRP2 MYH14 ICA1 PKHD1

2.00e-04192674c15841f35e24d6ef6ce2a9a6dc62e66efdc3d9d5
ToppCellfacs-Lung-24m-Epithelial-alveolar_epithelial-type_II_pneumocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESRP2 ELMO3 PTPRF MYH14

2.04e-0419367468adc680deb2f1a29d3cca19c13b9f6271dd4d60
Drugmephenytoin

EPHX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.29e-0688655CID000004060
Drugdichloran

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.66e-0641654CID000007430
Drugfelodipine

CACNA2D2 CYP4F2 CYP4F3 CYP4F12 CYP4F11 LEPR

8.80e-06169656CID000003333
Drugmono-(2-ethylhexyl)phthalate

EPHX1 OTOA RNF123 MYOM3 SREBF2 PKHD1 CTH RIMS1 ASCC3 SOAT2

1.62e-056586510ctd:C016599
Drugpleuromutilin

CYP4F2 CYP4F12 COG8

1.76e-0518653CID000031326
DrugFluphenazine dihydrochloride [146-56-5]; Up 200; 7.8uM; PC3; HT_HG-U133A

ELMO3 ICA1 CALCOCO1 SREBF2 DAPK3 CTH

1.93e-051946565880_UP
DrugDinoprost trometamol [38362-01-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A

ELMO3 CALCOCO1 SREBF2 DAPK3 TUT1 LEPR

2.04e-051966565409_DN
Drug8-MOP

CYP4F2 CYP4F3 CYP4F12 CYP4F11 DDB1

2.21e-05118655CID000004114
Drugdiclofenac

ABCC4 TKFC CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.93e-05209656CID000003032
Drugclofibrate

EPHX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11 SOAT2 COG8

2.93e-05311657CID000002796
Drugpropoxyphene

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.05e-0567654CID000010100
Drugaminoglutethimide

TKFC CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.53e-05137655CID000002145
Drugebastine

CYP4F2 CYP4F3 CYP4F12

4.88e-0525653CID000003191
Drugcarteolol

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.38e-0572654CID000002583
Diseasehexadecenedioate (C16:1-DC) measurement

CYP4F2 CYP4F11

1.81e-049672EFO_0800562
Diseasecoffee consumption measurement

DHX15 PTPRF CACNA2D2 PKHD1

7.93e-04182674EFO_0006781
Diseaseage at voice drop

CACNA2D2 LEPR

1.14e-0322672EFO_0007888
DiseaseSubfertility, Female

CACNA2D2 LEPR

1.85e-0328672C0341869
DiseaseSterility, Postpartum

CACNA2D2 LEPR

1.85e-0328672C0038279
DiseaseFemale sterility

CACNA2D2 LEPR

1.85e-0328672C0917730
DiseaseFemale infertility

CACNA2D2 LEPR

1.85e-0328672C0021361

Protein segments in the cluster

PeptideGeneStartEntry
ELLLLRDDGEEEFAG

CCAR2

651

Q8N163
GFELVTDLILADFLL

ARMT1

256

Q9H993
LILELVAGGELFDFL

DAPK1

91

P53355
ELDLSELEGLGLSDT

MLLT11

21

Q13015
EDLLCVLIDDGGFLV

CACNA2D2

886

Q9NY47
LKEFDLDALLGIDDL

ATF4

91

P18848
LSVGLEDEEDLLEDL

CTH

376

P32929
LVLTLEGEDLGELDK

CLSTN1

586

O94985
EEEEGDLLLFLTGQE

DHX15

346

O43143
LGSGEELDLLSEILD

DENND1C

551

Q8IV53
SELEDDLLGEDLLSG

RBM33

41

Q96EV2
DGLDLKDIIIDLGEI

OTOA

131

Q7RTW8
EILLDLGFGADEPDI

ITPRID1

146

Q6ZRS4
LGEELEALRGELEDT

MYH14

1161

Q7Z406
LDSLDGLALDIVSGL

PNMA6F

296

A0A0J9YX94
FDIELLELVAGLPEG

FKBP9P1

41

Q75LS8
LSEEELLDKLEIFFG

IFI35

146

P80217
LLDVFLGLETDGEEL

GHDC

206

Q8N2G8
DSEILDLESELYLGG

NRXN2

616

Q9P2S2
AALGEVEDEGLLASL

COG8

16

Q96MW5
LILELVSGGELFDFL

DAPK3

91

O43293
LTFSEGLDELLKLEG

LEPR

1051

P48357
VDEELGLDLGDLSRF

PDIA2

236

Q13087
ALDDDGDLSDLGVIL

DQX1

451

Q8TE96
TLDEGLIEFGTAIDD

IFT172

591

Q9UG01
LDLTDAIEEGTLDGL

IFT172

1601

Q9UG01
LGEILIELETALLDD

RIMS1

846

Q86UR5
DLQLLEDGDLTVIGD

ABCC4

516

O15439
LTESLFLDLLGEENG

IL4R

406

P24394
EDGGLERKFSLDDLL

EPHX1

341

P07099
ILSEEDGDDLLLKAE

CPLANE1

1166

Q9H799
LVTELFDTELIGEGA

PRMT7

141

Q9NVM4
LILELVSGGELFDFL

DAPK2

101

Q9UIK4
LEAELEKLSLSEGGL

CHMP7

421

Q8WUX9
LDFIDVLLLSKDEDG

CYP4F11

296

Q9HBI6
LDFIDVLLLSKDEDG

CYP4F12

296

Q9HCS2
NLFILLLGKEDGEEE

TMEM132E-DT

116

A2RUQ5
TIIEDGDDLGEVLAL

ELMO3

131

Q96BJ8
LDFIDVLLLSKDEDG

CYP4F2

296

P78329
GFLLPDSDVEIDLEL

INPP5B

726

P32019
EEGEDVVGDILADLL

C2orf81

51

A6NN90
LDFIDVLLLSKDEDG

CYP4F3

296

Q08477
AGEQELLLLLEPEEF

EME2

136

A4GXA9
DLLAFLLEESGDLGT

CREB3

11

O43889
ELVTLEEADGGSDIL

CALCOCO1

126

Q9P1Z2
DLGEKTFEGDIQELL

COL5A3

191

P25940
TGFIDGDLIESFLDI

DDB1

1086

Q16531
ELELDELLEAIEQGG

PTPRF

1156

P10586
RELLATLEGLDLDGE

PARP10

596

Q53GL7
EGADKDDLLLLSEIF

ICA1

366

Q05084
DLELESEQEAGLGLD

SLC26A8

861

Q96RN1
GLGLDLDLDRELEPE

SLC26A8

871

Q96RN1
EAEEFQLEVSGLLGE

FAM98A

71

Q8NCA5
ELPLELGEAILAEEF

SELENOO

396

Q9BVL4
LFEVGDAVEGLELTE

PKHD1

331

P08F94
LGRDLGSDETDLILL

ESRP2

41

Q9H6T0
LDDGLEGLFEDIDTS

SERTAD1

166

Q9UHV2
IDFIDEGRLLLEFDL

SOAT2

141

O75908
GDELQDELFELLGPE

ASCC3

261

Q8N3C0
DELFELLGPEGLELI

ASCC3

266

Q8N3C0
FEELILLLEAALGLE

CLTCL1

1296

P53675
LEELGLDLESGEESN

ZBTB11

136

O95625
GFEGLLLVDDDLLGV

RNF123

101

Q5XPI4
DLDLFLDLGDLEEPQ

TUT1

216

Q9H6E5
LTELGDELTLGDIDE

SREBF2

16

Q12772
SLCKLEGGEELEEEL

ZBTB47

206

Q9UFB7
TFELSADEVELGLGI

TKFC

206

Q3LXA3
GLLGDATEEFIESLD

UBR4

4446

Q5T4S7
LLELLLEEDDGTGLC

ZFYVE26

171

Q68DK2
GEDDTILDLTGDALD

MYOM3

1196

Q5VTT5