Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH10 DNAH8 DYNC1H1	5.40e-05	18	83	3	GO:0008569
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH10 DNAH8 DYNC1H1	2.10e-04	28	83	3	GO:0051959
GeneOntologyBiologicalProcess	coronary vein morphogenesis	NOTCH1 VEGFA	1.56e-05	2	82	2	GO:0003169
GeneOntologyBiologicalProcess	ventricular trabecula myocardium morphogenesis	NRG1 CHD7 NOTCH1	3.96e-05	17	82	3	GO:0003222
GeneOntologyBiologicalProcess	negative regulation of type I interferon production	CUL3 HAVCR2 GPATCH3 RELB	6.31e-05	54	82	4	GO:0032480
GeneOntologyBiologicalProcess	trabecula morphogenesis	NRG1 CHD7 NOTCH1 VEGFA	7.81e-05	57	82	4	GO:0061383
MousePheno	abnormal fourth pharyngeal arch morphology	BAZ1B CHD7 PLXND1 VEGFA	3.98e-06	23	67	4	MP:0006340
MousePheno	abnormal fourth pharyngeal arch artery morphology	CHD7 PLXND1 VEGFA	6.82e-05	17	67	3	MP:0006354
MousePheno	abnormal sixth pharyngeal arch artery morphology	CHD7 PLXND1 VEGFA	8.16e-05	18	67	3	MP:0006355
MousePheno	abnormal sixth pharyngeal arch morphology	CHD7 PLXND1 VEGFA	8.16e-05	18	67	3	MP:0006347
Domain	DHC_N1	DNAH10 DNAH8 DYNC1H1	4.50e-06	8	82	3	PF08385
Domain	Dynein_heavy_dom-1	DNAH10 DNAH8 DYNC1H1	4.50e-06	8	82	3	IPR013594
Domain	Dynein_heavy_chain_D4_dom	DNAH10 DNAH8 DYNC1H1	2.87e-05	14	82	3	IPR024317
Domain	Dynein_HC_stalk	DNAH10 DNAH8 DYNC1H1	2.87e-05	14	82	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH10 DNAH8 DYNC1H1	2.87e-05	14	82	3	IPR013602
Domain	DHC_N2	DNAH10 DNAH8 DYNC1H1	2.87e-05	14	82	3	PF08393
Domain	MT	DNAH10 DNAH8 DYNC1H1	2.87e-05	14	82	3	PF12777
Domain	AAA_8	DNAH10 DNAH8 DYNC1H1	2.87e-05	14	82	3	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH10 DNAH8 DYNC1H1	2.87e-05	14	82	3	IPR011704
Domain	AAA_5	DNAH10 DNAH8 DYNC1H1	2.87e-05	14	82	3	PF07728
Domain	DHC_fam	DNAH10 DNAH8 DYNC1H1	3.57e-05	15	82	3	IPR026983
Domain	Dynein_heavy_dom	DNAH10 DNAH8 DYNC1H1	3.57e-05	15	82	3	IPR004273
Domain	Dynein_heavy	DNAH10 DNAH8 DYNC1H1	3.57e-05	15	82	3	PF03028
Domain	Amyloid_glyco_E2_domain	APLP1 APLP2	5.70e-05	3	82	2	IPR024329
Domain	A4_EXTRA	APLP1 APLP2	5.70e-05	3	82	2	PS00319
Domain	Amyloid_glyco_heparin-bd	APLP1 APLP2	5.70e-05	3	82	2	IPR015849
Domain	APP_Cu_bd	APLP1 APLP2	5.70e-05	3	82	2	PF12924
Domain	APP_E2	APLP1 APLP2	5.70e-05	3	82	2	PF12925
Domain	APP_amyloid	APLP1 APLP2	5.70e-05	3	82	2	PF10515
Domain	A4_INTRA	APLP1 APLP2	5.70e-05	3	82	2	PS00320
Domain	Amyloid_glyco	APLP1 APLP2	5.70e-05	3	82	2	IPR008155
Domain	Amyloid_glyco_extra	APLP1 APLP2	5.70e-05	3	82	2	IPR008154
Domain	-	APLP1 APLP2	5.70e-05	3	82	2	3.90.570.10
Domain	-	APLP1 APLP2	5.70e-05	3	82	2	3.30.1490.140
Domain	APP_amyloid_C	APLP1 APLP2	5.70e-05	3	82	2	IPR019543
Domain	Amyloid_glyco_extracell_CS	APLP1 APLP2	5.70e-05	3	82	2	IPR019744
Domain	Amyloid_glyco_intracell_CS	APLP1 APLP2	5.70e-05	3	82	2	IPR019745
Domain	Amyloid_glyco_Cu-bd	APLP1 APLP2	5.70e-05	3	82	2	IPR011178
Domain	APP_N	APLP1 APLP2	5.70e-05	3	82	2	PF02177
Domain	A4_EXTRA	APLP1 APLP2	5.70e-05	3	82	2	SM00006
Domain	DNA/RNA_helicase_DEAH_CS	DHX16 CHD7 FANCM	4.82e-04	35	82	3	IPR002464
Domain	RA	RGL1 RALGDS ARAP3	5.25e-04	36	82	3	PF00788
Domain	RA	RGL1 RALGDS ARAP3	5.69e-04	37	82	3	PS50200
Domain	DEAH_ATP_HELICASE	DHX16 CHD7 FANCM	6.16e-04	38	82	3	PS00690
Domain	RA_dom	RGL1 RALGDS ARAP3	7.17e-04	40	82	3	IPR000159
Domain	Helicase_C	DHX16 CHD7 FANCM DDX39A	1.26e-03	107	82	4	PF00271
Domain	HELICc	DHX16 CHD7 FANCM DDX39A	1.26e-03	107	82	4	SM00490
Domain	Helicase_C	DHX16 CHD7 FANCM DDX39A	1.31e-03	108	82	4	IPR001650
Domain	HELICASE_CTER	DHX16 CHD7 FANCM DDX39A	1.35e-03	109	82	4	PS51194
Domain	HELICASE_ATP_BIND_1	DHX16 CHD7 FANCM DDX39A	1.35e-03	109	82	4	PS51192
Domain	DEXDc	DHX16 CHD7 FANCM DDX39A	1.35e-03	109	82	4	SM00487
Domain	Helicase_ATP-bd	DHX16 CHD7 FANCM DDX39A	1.40e-03	110	82	4	IPR014001
Domain	Ras_G-nucl-exch_fac_CS	RGL1 RALGDS	1.67e-03	14	82	2	IPR019804
Domain	RasGEFN	RGL1 RALGDS	3.44e-03	20	82	2	SM00229
Domain	RasGEF_N	RGL1 RALGDS	3.79e-03	21	82	2	PF00618
Domain	P-loop_NTPase	DHX16 SAMD9 DNAH10 MYO1B CHD7 GTPBP1 FANCM DDX39A DNAH8 DYNC1H1	3.92e-03	848	82	10	IPR027417
Domain	DEAD/DEAH_box_helicase_dom	DHX16 FANCM DDX39A	4.07e-03	73	82	3	IPR011545
Domain	DEAD	DHX16 FANCM DDX39A	4.07e-03	73	82	3	PF00270
Domain	Ras-like_Gua-exchang_fac_N	RGL1 RALGDS	4.15e-03	22	82	2	IPR000651
Domain	RASGEF_NTER	RGL1 RALGDS	4.15e-03	22	82	2	PS50212
Domain	-	DHX16 SAMD9 DNAH10 CHD7 GTPBP1 FANCM DDX39A DNAH8 DYNC1H1	5.35e-03	746	82	9	3.40.50.300
Domain	RASGEF	RGL1 RALGDS	5.78e-03	26	82	2	PS00720
Domain	IPT	RELB PLXND1	6.22e-03	27	82	2	SM00429
Domain	Rho_GTPase_activation_prot	ARAP3 RASA3 PLXND1	6.85e-03	88	82	3	IPR008936
Domain	RASGEF_CAT	RGL1 RALGDS	7.16e-03	29	82	2	PS50009
Domain	RasGEF	RGL1 RALGDS	7.65e-03	30	82	2	PF00617
Domain	-	RGL1 RALGDS	7.65e-03	30	82	2	1.10.840.10
Domain	Ras_GEF_dom	RGL1 RALGDS	7.65e-03	30	82	2	IPR023578
Domain	RASGEF_cat_dom	RGL1 RALGDS	7.65e-03	30	82	2	IPR001895
Domain	RasGEF	RGL1 RALGDS	7.65e-03	30	82	2	SM00147
Domain	TIG	RELB PLXND1	8.15e-03	31	82	2	PF01833
Domain	RA	RGL1 RALGDS	8.15e-03	31	82	2	SM00314
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DHX16 CUL3 UBR1 RALGDS LLGL2 SAMD9 ARAP3 GTPBP1 CLSPN SF3B2 POLR3A	4.26e-07	650	83	11	38777146
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MIS18BP1 RBM33 ZNF451 BAZ1B PPP1R13B MYO1B ZDBF2 CHD7 CLSPN HSF2	1.42e-06	588	83	10	38580884
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	DHX16 CUL3 CKAP5 BAZ1B APLP2 GTPBP1 SF3B2	2.44e-06	251	83	7	28077445
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DHX16 UBR1 PDCD2 MIS18BP1 ARAP3 RASA3 CKAP5 BAZ1B MYO1B CHD7 DDX39A SF3B2 DYNC1H1 POLR3A	3.65e-06	1353	83	14	29467282
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH10 DNAH8 DYNC1H1	4.68e-06	14	83	3	9373155
Pubmed	Structural aspects and physiological consequences of APP/APLP trans-dimerization.	APLP1 APLP2	5.63e-06	2	83	2	21952790
Pubmed	Accumulation of the amyloid precursor-like protein APLP2 and reduction of APLP1 in retinoic acid-differentiated human neuroblastoma cells upon curcumin-induced neurite retraction.	APLP1 APLP2	5.63e-06	2	83	2	14597230
Pubmed	PEST sequences mediate heat shock factor 2 turnover by interacting with the Cul3 subunit of the Cul3-RING ubiquitin ligase.	CUL3 HSF2	5.63e-06	2	83	2	19768582
Pubmed	Shear stress promotes differentiation of stem cells from human exfoliated deciduous teeth into endothelial cells via the downstream pathway of VEGF-Notch signaling.	NOTCH1 VEGFA	5.63e-06	2	83	2	30015843
Pubmed	Functions of the APP gene family in the nervous system: insights from mouse models.	APLP1 APLP2	5.63e-06	2	83	2	21931985
Pubmed	A Notch1-neuregulin1 autocrine signaling loop contributes to melanoma growth.	NRG1 NOTCH1	5.63e-06	2	83	2	22249266
Pubmed	The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation.	APLP1 APLP2	5.63e-06	2	83	2	14970212
Pubmed	The amyloid beta-protein precursor and its mammalian homologues. Evidence for a zinc-modulated heparin-binding superfamily.	APLP1 APLP2	5.63e-06	2	83	2	7929392
Pubmed	Amyloid-precursor Like Proteins APLP1 and APLP2 Are Dispensable for Normal Development of the Neonatal Respiratory Network.	APLP1 APLP2	5.63e-06	2	83	2	28690498
Pubmed	CDEBP, a site-specific DNA-binding protein of the 'APP-like' family, is required during the early development of the mouse.	APLP1 APLP2	5.63e-06	2	83	2	7539437
Pubmed	Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription.	APLP1 APLP2	5.63e-06	2	83	2	12228233
Pubmed	Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response.	CARM1 NOTCH1	5.63e-06	2	83	2	25805888
Pubmed	Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart.	NRG1 NOTCH1 VEGFA	5.84e-06	15	83	3	25072663
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	INTS2 RASA3 CKAP5 PPP1R13B MYO1B DDX39A SF3B2 DYNC1H1 POLR3A	9.35e-06	573	83	9	28330616
Pubmed	eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling.	NRG1 NOTCH1 VEGFA	1.04e-05	18	83	3	38111957
Pubmed	Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.	APLP1 APLP2	1.69e-05	3	83	2	11050115
Pubmed	Gene silencing analyses against amyloid precursor protein (APP) gene family by RNA interference.	APLP1 APLP2	1.69e-05	3	83	2	16889988
Pubmed	Lengthening of G2/mitosis in cortical precursors from mice lacking beta-amyloid precursor protein.	APLP1 APLP2	1.69e-05	3	83	2	15561424
Pubmed	Antiangiogenic and tumour inhibitory effects of downregulating tumour endothelial FABP4.	NOTCH1 VEGFA	1.69e-05	3	83	2	27568980
Pubmed	Heregulin-induced VEGF expression via the ErbB3 signaling pathway in colon cancer.	NRG1 VEGFA	1.69e-05	3	83	2	19797898
Pubmed	RalGDS-like factor (Rlf) is a novel Ras and Rap 1A-associating protein.	RGL1 RALGDS	1.69e-05	3	83	2	8710374
Pubmed	Differential role of APP and APLPs for neuromuscular synaptic morphology and function.	APLP1 APLP2	1.69e-05	3	83	2	24998676
Pubmed	Synchronization of endothelial Dll4-Notch dynamics switch blood vessels from branching to expansion.	NOTCH1 VEGFA	1.69e-05	3	83	2	27074663
Pubmed	Cross-talk between leukemic and endothelial cells promotes angiogenesis by VEGF activation of the Notch/Dll4 pathway.	NOTCH1 VEGFA	1.69e-05	3	83	2	23239744
Pubmed	Regulation of gene expression by the APP family in the adult cerebral cortex.	APLP1 APLP2	1.69e-05	3	83	2	34997052
Pubmed	Dll4-Notch1 signaling but not VEGF-A is essential for hyperoxia induced vessel regression in retina.	NOTCH1 VEGFA	1.69e-05	3	83	2	30448061
Pubmed	Amyloid precursor proteins are constituents of the presynaptic active zone.	APLP1 APLP2	1.69e-05	3	83	2	23815291
Pubmed	Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis.	NOTCH1 VEGFA	1.69e-05	3	83	2	12482957
Pubmed	Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A.	NOTCH1 VEGFA	1.69e-05	3	83	2	19407245
Pubmed	Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism.	PLXND1 VEGFA	1.69e-05	3	83	2	21724832
Pubmed	APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival.	APLP1 APLP2	1.69e-05	3	83	2	32891188
Pubmed	Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2.	APLP1 APLP2	1.69e-05	3	83	2	19126676
Pubmed	APLP2 regulates neuronal stem cell differentiation during cortical development.	APLP1 APLP2	1.69e-05	3	83	2	23345401
Pubmed	Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells.	PRKD2 VEGFA	1.69e-05	3	83	2	20497126
Pubmed	The role of Notch signaling in diabetic endothelial progenitor cells dysfunction.	NOTCH1 VEGFA	1.69e-05	3	83	2	26598222
Pubmed	Expression of EGFR, VEGF, and NOTCH1 suggest differences in tumor angiogenesis in HPV-positive and HPV-negative head and neck squamous cell carcinoma.	NOTCH1 VEGFA	1.69e-05	3	83	2	23645351
Pubmed	Homo- and heterodimerization of APP family members promotes intercellular adhesion.	APLP1 APLP2	1.69e-05	3	83	2	16193067
Pubmed	GDF-15 Level Correlates with CMKLR1 and VEGF-A in Tumor-free Margin in Colorectal Cancer.	CMKLR1 VEGFA	1.69e-05	3	83	2	34169422
Pubmed	A human MAP kinase interactome.	RGL1 RALGDS ARL2BP RBM33 JADE2 ZNF451 PPP1R13B APLP2	2.16e-05	486	83	8	20936779
Pubmed	Tie2 regulates endocardial sprouting and myocardial trabeculation.	NRG1 ARAP3 PLXND1 NOTCH1	2.19e-05	68	83	4	31112136
Pubmed	Dimerization quality control ensures neuronal development and survival.	CUL3 KLHL7 PKN1	2.56e-05	24	83	3	30190310
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	TRAF5 C2CD3 CKAP5 CEP164 DYNC1H1	2.72e-05	146	83	5	21399614
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DHX16 PRKD2 DNAH10 DUT CKAP5 MAK16 BAZ1B MYO1B APLP2 GTPBP1 SF3B2 DYNC1H1 POLR3A	3.18e-05	1425	83	13	30948266
Pubmed	Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis.	CLSPN FANCM	3.37e-05	4	83	2	19270156
Pubmed	Loss of all three APP family members during development impairs synaptic function and plasticity, disrupts learning, and causes an autism-like phenotype.	APLP1 APLP2	3.37e-05	4	83	2	34008862
Pubmed	Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1.	APLP1 APLP2	3.37e-05	4	83	2	10460257
Pubmed	Signaling via amyloid precursor-like proteins APLP1 and APLP2.	APLP1 APLP2	3.37e-05	4	83	2	21178287
Pubmed	Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage.	APLP1 APLP2	3.37e-05	4	83	2	14983046
Pubmed	Presence of a "CAGA box" in the APP gene unique to amyloid plaque-forming species and absent in all APLP-1/2 genes: implications in Alzheimer's disease.	APLP1 APLP2	3.37e-05	4	83	2	15208260
Pubmed	cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein.	APLP1 APLP2	3.37e-05	4	83	2	8894693
Pubmed	DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries.	NOTCH1 VEGFA	3.37e-05	4	83	2	19144989
Pubmed	Combination DLL4 with Jagged1-siRNA can enhance inhibition of the proliferation and invasiveness activity of human gastric carcinoma by Notch1/VEGF pathway.	NOTCH1 VEGFA	3.37e-05	4	83	2	22020917
Pubmed	Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.	APLP1 APLP2	3.37e-05	4	83	2	16314516
Pubmed	Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1.	DNAH8 DYNC1H1	3.37e-05	4	83	2	15762842
Pubmed	Arachidonic acid potentiates hypoxia-induced VEGF expression in mouse embryonic stem cells: involvement of Notch, Wnt, and HIF-1alpha.	NOTCH1 VEGFA	3.37e-05	4	83	2	19339510
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	INTS2 CKAP5 MYO1B ZDBF2 SF3B2 DYNC1H1	4.94e-05	272	83	6	31010829
Pubmed	Notch, IL-1 and leptin crosstalk outcome (NILCO) is critical for leptin-induced proliferation, migration and VEGF/VEGFR-2 expression in breast cancer.	NOTCH1 VEGFA	5.60e-05	5	83	2	21731759
Pubmed	Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter.	APLP1 APLP2	5.60e-05	5	83	2	17709753
Pubmed	Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's beta-amyloid precursor protein.	APLP1 APLP2	5.60e-05	5	83	2	10081969
Pubmed	Tetralogy of fallot and alterations in vascular endothelial growth factor-A signaling and notch signaling in mouse embryos solely expressing the VEGF120 isoform.	NOTCH1 VEGFA	5.60e-05	5	83	2	17332426
Pubmed	APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission.	APLP1 APLP2	5.60e-05	5	83	2	28450540
Pubmed	Ubiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation.	CUL3 KLHL7	5.60e-05	5	83	2	21828050
Pubmed	Regulation of tumor angiogenesis by the local environment.	NOTCH1 VEGFA	5.60e-05	5	83	2	20036815
Pubmed	Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1.	HAVCR2 VEGFA	5.60e-05	5	83	2	22842346
Pubmed	APLP1 and APLP2, members of the APP family of proteins, behave similarly to APP in that they associate with NMDA receptors and enhance NMDA receptor surface expression.	APLP1 APLP2	5.60e-05	5	83	2	25683482
Pubmed	Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signalling.	APLP1 APLP2	5.60e-05	5	83	2	21293490
Pubmed	The Dll4/Notch pathway controls postangiogenic blood vessel remodeling and regression by modulating vasoconstriction and blood flow.	NOTCH1 VEGFA	5.60e-05	5	83	2	21498671
Pubmed	Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction.	NRG1 PLXND1 NOTCH1	6.18e-05	32	83	3	31434798
Pubmed	Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1.	APLP1 APLP2	8.39e-05	6	83	2	14699153
Pubmed	The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis.	PRKD2 VEGFA	8.39e-05	6	83	2	18059339
Pubmed	Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis.	APLP1 APLP2	8.39e-05	6	83	2	19726636
Pubmed	Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling.	NOTCH1 VEGFA	8.39e-05	6	83	2	22426001
Pubmed	Integrated RAS signaling defined by parallel NMR detection of effectors and regulators.	RGL1 RALGDS	8.39e-05	6	83	2	24441586
Pubmed	Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.	NRG1 NOTCH1 VEGFA	1.04e-04	38	83	3	29743679
Pubmed	Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members.	APLP1 APLP2	1.17e-04	7	83	2	15385965
Pubmed	Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1.	PLXND1 VEGFA	1.17e-04	7	83	2	17318185
Pubmed	A novel tumor-promoting function residing in the 5' non-coding region of vascular endothelial growth factor mRNA.	NRG1 VEGFA	1.17e-04	7	83	2	18494554
Pubmed	Dysfunctional SEMA3E signaling underlies gonadotropin-releasing hormone neuron deficiency in Kallmann syndrome.	CHD7 PLXND1	1.17e-04	7	83	2	25985275
Pubmed	Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein.	APLP1 APLP2	1.17e-04	7	83	2	7542371
Pubmed	Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.	CLSPN SF3B2 DYNC1H1	1.51e-04	43	83	3	34672947
Pubmed	Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase.	PRKD2 VEGFA	1.56e-04	8	83	2	18440775
Pubmed	Biochemical characterization of the Ras-related GTPases Rit and Rin.	RGL1 RALGDS	1.56e-04	8	83	2	10545207
Pubmed	Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neovascularization.	NOTCH1 VEGFA	1.56e-04	8	83	2	26659946
Pubmed	Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development.	NOTCH1 VEGFA	1.56e-04	8	83	2	23319657
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	MIS18BP1 MAK16 BAZ1B DDX39A SF3B2 DYNC1H1	1.67e-04	340	83	6	29478914
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DHX16 CKAP5 MAK16 BAZ1B MYO1B CHD7 SF3B2 DYNC1H1	1.69e-04	653	83	8	22586326
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	DHX16 CUL3 SAMD9 KLHL7 CKAP5 MAK16 BAZ1B MYO1B GTPBP1 SF3B2 DYNC1H1	1.96e-04	1257	83	11	36526897
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	CUL3 C2CD3 MIS18BP1 KLHL7 CKAP5 PPP1R13B GTPBP1 CEP164 DYNC1H1	2.00e-04	853	83	9	28718761
Pubmed	Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.	NOTCH1 VEGFA	2.00e-04	9	83	2	17948123
Pubmed	Hypoxia-responsive microRNA-101 promotes angiogenesis via heme oxygenase-1/vascular endothelial growth factor axis by targeting cullin 3.	CUL3 VEGFA	2.00e-04	9	83	2	24844779
Pubmed	A Snail1/Notch1 signalling axis controls embryonic vascular development.	NOTCH1 VEGFA	2.00e-04	9	83	2	24894949
Pubmed	Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2.	APLP1 APLP2	2.00e-04	9	83	2	11247302
Pubmed	Dll4 and Notch signalling couples sprouting angiogenesis and artery formation.	NOTCH1 VEGFA	2.00e-04	9	83	2	28714968
Pubmed	The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.	RALGDS MIS18BP1 RASA3 BLNK CLSPN	2.18e-04	227	83	5	26410627
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	CARM1 UNC5C CKAP5 CHD7 DYNC1H1 NOTCH1	2.21e-04	358	83	6	32460013
Cytoband	14q21.2	MIS18BP1 FANCM	6.01e-04	20	83	2	14q21.2
Cytoband	9q34.3	RALGDS PNPLA7 NOTCH1	9.61e-04	106	83	3	9q34.3
Cytoband	2q33.3	ZDBF2 PLEKHM3	1.36e-03	30	83	2	2q33.3
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	ARAP3 PCDHGB7 JADE2 PCDHB1	2.14e-03	298	83	4	chr5q31
Cytoband	8p12	NRG1 MAK16	3.31e-03	47	83	2	8p12
Cytoband	19p13.12	PKN1 DDX39A	3.74e-03	50	83	2	19p13.12
Coexpression	ZHENG_GLIOBLASTOMA_PLASTICITY_UP	MIS18BP1 UNC5C DUT APLP1 MYO1B CLSPN DDX39A	1.23e-05	249	81	7	M1796
Coexpression	ZHENG_GLIOBLASTOMA_PLASTICITY_UP	MIS18BP1 UNC5C DUT APLP1 MYO1B CLSPN DDX39A	1.51e-05	257	81	7	MM1231
Coexpression	GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_DN	SAMD9 ARAP3 APLP2 CMKLR1 PCDHB1 NOTCH1	3.39e-05	197	81	6	M7696
Coexpression	GSE30083_SP1_VS_SP4_THYMOCYTE_DN	TRAF5 RASA3 PLEKHM3 PNPLA7 DNAH8 GRAMD4	3.69e-05	200	81	6	M5030
Coexpression	GSE339_CD4POS_VS_CD8POS_DC_UP	RGL1 MYO1B RELB PLXND1 RYR3 VEGFA	3.69e-05	200	81	6	M5108
Coexpression	GSE339_CD8POS_VS_CD4CD8DN_DC_DN	RGL1 KLHL7 MYO1B RELB PLXND1 RYR3	3.69e-05	200	81	6	M5118
Coexpression	GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TCONV_DN	CUL3 NRG1 GPATCH3 MYO1B ZFTA GRAMD4	3.69e-05	200	81	6	M8966
Coexpression	GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_UP	TRAF5 RASA3 P3H3 APLP2 PLXND1 RYR3	3.69e-05	200	81	6	M9073
Coexpression	GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_UP	B3GALT4 CUL3 SAMD9 APLP2 ADGRV1 GTPBP1	3.69e-05	200	81	6	M5528
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN	CUL3 ARAP3 RBM33 ZNF451 MAK16 ZDBF2 RELB CHD7 GTPBP1 VEGFA	4.63e-05	680	81	10	M41089
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_SMALL_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP	TDRKH MIS18BP1 INTS2 DUT CKAP5 APLP1 CHD7 CLSPN FANCM HSF2	4.63e-05	680	81	10	MM456
Coexpression	BLANCO_MELO_COVID19_SARS_COV_2_POS_PATIENT_LUNG_TISSUE_DN	RALGDS ARAP3 RASA3 ZNF451 PPP1R13B	2.13e-04	175	81	5	M34029
Coexpression	GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP	HAVCR2 MIS18BP1 CHD7 CMKLR1 CLSPN	2.19e-04	176	81	5	M2981
Coexpression	BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	CUL3 PRKD2 RGL1 NRG1 RALGDS GPATCH3 RELB HSF2 NOTCH1 VEGFA	2.19e-04	822	81	10	M6782
Coexpression	RANKIN_ANGIOGENIC_TARGETS_OF_VHL_HIF2A_DN	PLXND1 VEGFA	2.61e-04	8	81	2	M1337
Coexpression	RANKIN_ANGIOGENIC_TARGETS_OF_VHL_HIF2A_DN	PLXND1 VEGFA	2.61e-04	8	81	2	MM556
Coexpression	GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_DN	NRG1 SAMD9 DNAH10 CLSPN RYR3	3.27e-04	192	81	5	M4277
Coexpression	GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP	SAMD9 DUT BAZ1B PRIMPOL CNDP1	3.35e-04	193	81	5	M5339
Coexpression	GSE22886_NAIVE_BCELL_VS_MONOCYTE_UP	TRAF5 C2CD3 BLNK ZFTA CHD7	3.68e-04	197	81	5	M4485
Coexpression	GSE10325_BCELL_VS_MYELOID_UP	PRKD2 TRAF5 JADE2 BLNK GTPBP1	3.68e-04	197	81	5	M3081
Coexpression	GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN	RGL1 ARL2BP JADE2 BLNK CMKLR1	3.76e-04	198	81	5	M4606
Coexpression	GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN	ARL2BP TRAF5 C2CD3 SAMD9 JADE2	3.76e-04	198	81	5	M7610
Coexpression	GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_DN	VPS13D PKN1 CHD7 PNPLA7 DYNC1H1	3.85e-04	199	81	5	M316
Coexpression	GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN	LLGL2 CHD7 DNAH8 NOTCH1 VEGFA	3.85e-04	199	81	5	M4571
Coexpression	GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_UP	CARM1 PANK3 ZNF451 DENND2B VEGFA	3.85e-04	199	81	5	M5213
Coexpression	GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_DN	DHX16 CKAP5 APLP1 PLXND1 SF3B2	3.85e-04	199	81	5	M5249
Coexpression	GSE3982_MAC_VS_TH1_DN	TRAF5 RASA3 CLSPN HSF2 TFR2	3.85e-04	199	81	5	M5511
Coexpression	GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP	B3GALT4 RASA3 PPP1R13B RELB CHD7	3.85e-04	199	81	5	M6197
Coexpression	GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN	RASA3 ZNF451 ZFTA DNAH8 VEGFA	3.85e-04	199	81	5	M9178
Coexpression	GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_DN	PANK3 RBM33 PLEKHM3 PNPLA7 DYNC1H1	3.94e-04	200	81	5	M5043
Coexpression	GSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_UP	PDCD2 KLHL7 P3H3 APLP1 CMKLR1	3.94e-04	200	81	5	M5122
Coexpression	GSE30083_SP1_VS_SP3_THYMOCYTE_DN	TRAF5 RASA3 BAZ1B DNAH8 GRAMD4	3.94e-04	200	81	5	M5026
Coexpression	GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP	RALGDS ARL2BP LLGL2 PLXND1 DYNC1H1	3.94e-04	200	81	5	M9671
Coexpression	GSE3982_DC_VS_MAC_LPS_STIM_UP	B3GALT4 TRAF5 C2CD3 CKAP5 BAZ1B	3.94e-04	200	81	5	M5387
Coexpression	GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP	MIS18BP1 DUT CKAP5 APLP2 CLSPN	3.94e-04	200	81	5	M3580
Coexpression	GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_UP	TRAF5 JADE2 BLNK MAK16 GRAMD4	3.94e-04	200	81	5	M5241
Coexpression	GSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN	CUL3 TRAF5 RELB PLXND1 NOTCH1	3.94e-04	200	81	5	M7271
Coexpression	GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP	RALGDS TRAF5 CHD7 CMKLR1 DDX39A	3.94e-04	200	81	5	M8650
Coexpression	GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_UP	CARM1 RGL1 CKAP5 BAZ1B MYO1B	3.94e-04	200	81	5	M9903
Coexpression	GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_UP	PDCD2 ARL2BP RASA3 PPP1R13B CMKLR1	3.94e-04	200	81	5	M7175
Coexpression	GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN	CARM1 PDCD2 KLHL7 CKAP5 VEGFA	3.94e-04	200	81	5	M3613
Coexpression	GSE15930_STIM_VS_STIM_AND_IFNAB_72H_CD8_T_CELL_DN	PDCD2 ARAP3 RYR3 POLR3A VEGFA	3.94e-04	200	81	5	M3646
Coexpression	GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_UP	CARM1 PRKD2 KLHL7 BLNK DYNC1H1	3.94e-04	200	81	5	M3675
Coexpression	GSE21379_TFH_VS_NON_TFH_CD4_TCELL_UP	ARL2BP JADE2 DNAH8 CEP164 VEGFA	3.94e-04	200	81	5	M7500
Coexpression	GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_DN	RALGDS ARL2BP RELB CHD7 VEGFA	3.94e-04	200	81	5	M5758
Coexpression	GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	RASA3 RBM33 CHD7 PNPLA7 DNAH8	3.94e-04	200	81	5	M9164
Coexpression	CHEN_METABOLIC_SYNDROM_NETWORK	HAVCR2 RGL1 NRG1 RALGDS TRAF5 GPATCH3 RASA3 P3H3 BLNK COL14A1 RELB CLSPN	4.17e-04	1242	81	12	M1920
Coexpression	MASSARWEH_TAMOXIFEN_RESISTANCE_UP	B3GALT4 TRAF5 ARAP3 KLHL7 IFT57 BLNK MYO1B GRAMD4	4.42e-04	583	81	8	M17454
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	RGL1 MIS18BP1 RASA3 KLHL7 FAT3 UNC5C PPP1R13B KYAT3 COL14A1 ZDBF2 CHD7 CLSPN HSF2 DENND2B VEGFA	3.34e-07	827	79	15	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	TDRKH IFT57 FAT3 CKAP5 ASTN1 APLP1 ZDBF2 CHD7 CLSPN	1.63e-06	298	79	9	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K4
CoexpressionAtlas	DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_1000	DHX16 TDRKH C2CD3 INTS2 RBM33 FAT3 UNC5C DUT CKAP5 MYO1B CHD7 ADGRV1 VEGFA	5.57e-06	779	79	13	gudmap_developingKidney_e15.5_Cap mesenchyme_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000	MIS18BP1 RASA3 KLHL7 FAT3 UNC5C KYAT3 COL14A1 ZDBF2 CHD7 CLSPN HSF2 DENND2B VEGFA	1.11e-05	831	79	13	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	CUL3 NRG1 TDRKH DNAH10 KLHL7 IFT57 FAT3 CKAP5 ASTN1 ZDBF2 CHD7 ADGRV1 CLSPN FANCM	1.42e-05	983	79	14	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500	NRG1 TDRKH DNAH10 FAT3 CKAP5 ASTN1 ZDBF2 CHD7 ADGRV1 CLSPN	1.43e-05	493	79	10	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5	TDRKH FAT3 CKAP5 ASTN1 ZDBF2 CHD7 CLSPN	2.52e-05	232	79	7	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	CUL3 TDRKH CACNG7 IFT57 FAT3 CKAP5 ASTN1 APLP1 ZDBF2 CHD7 CLSPN	2.93e-05	654	79	11	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#5	CUL3 CACNG7 C2CD3 KLHL7 IFT57 FAT3 ASTN1 APLP1 PKN1 ZDBF2 CHD7	4.65e-05	688	79	11	Facebase_RNAseq_e10.5_Mandibular Arch_2500_K5
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b+.SLN, CD11b-FITC CD4-PE CD11c-eFluor780 CD8a-eFluor450 C, Lymph Node, avg-1	HAVCR2 IFT57 BLNK APLP2 RELB PLXND1 HSF2 DENND2B	1.35e-04	407	79	8	GSM854287_500
CoexpressionAtlas	kidney_e10.5_UretericTrunk_HoxB7_k-means-cluster#2_top-relative-expression-ranked_100	FAT3 CHD7	1.36e-04	5	79	2	gudmap_kidney_e10.5_UretericTrunk_HoxB7_k2_100
CoexpressionAtlas	Myeloid Cells, DC.IIhilang+103-11b+.SLN, MHCIIhi CD11c+ Langerin+ CD103- CD11b+, Lymph Node, avg-3	IFT57 BLNK APLP2 RELB PLXND1 GTPBP1 HSF2 DENND2B	1.45e-04	411	79	8	GSM538271_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500	RASA3 FAT3 UNC5C KYAT3 COL14A1 ZDBF2 DENND2B VEGFA	1.62e-04	418	79	8	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#4	TDRKH FAT3 ASTN1 ZDBF2 CHD7	1.71e-04	139	79	5	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	TDRKH RBM33 FAT3 CKAP5 BAZ1B ASTN1 APLP1 ZDBF2 CHD7 CLSPN CEP164	2.46e-04	831	79	11	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#1_top-relative-expression-ranked_1000	TDRKH INTS2 RBM33 UNC5C DUT ADGRV1	2.80e-04	241	79	6	gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k1
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000	RGL1 RASA3 KLHL7 UNC5C PPP1R13B KYAT3 COL14A1 ZDBF2 CHD7 DENND2B VEGFA	2.95e-04	849	79	11	gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5	TDRKH CACNG7 C2CD3 KLHL7 FAT3 ASTN1 APLP1 PKN1 CHD7 ADGRV1	3.75e-04	732	79	10	Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K5
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	MIS18BP1 ZNF451 CLSPN HSF2 DDX39A PRIMPOL	4.02e-04	258	79	6	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k2_1000
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5	TDRKH CACNG7 C2CD3 KLHL7 IFT57 FAT3 ASTN1 APLP1 PKN1 ADGRV1	4.22e-04	743	79	10	Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#2	CACNG7 C2CD3 KLHL7 IFT57 FAT3 ASTN1 APLP1 PKN1 CHD7 ADGRV1	4.40e-04	747	79	10	Facebase_RNAseq_e9.5_Maxillary Arch_2500_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	CACNG7 C2CD3 FAT3 ASTN1 APLP1 PKN1 CHD7 ADGRV1 CLSPN	4.53e-04	614	79	9	Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#3	CUL3 BAZ1B ASTN1 ZDBF2 CHD7 CLSPN	5.21e-04	271	79	6	Facebase_RNAseq_e10.5_Mandibular Arch_1000_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	TDRKH FAT3 CKAP5 APLP1 ZDBF2 CHD7 ADGRV1 CLSPN	5.25e-04	498	79	8	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#2	TDRKH ASTN1 APLP1 ADGRV1	5.31e-04	100	79	4	Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500_K2
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 FAT3 UNC5C ASTN1 RIMBP2 ADGRV1 RYR3	1.92e-08	160	82	7	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 FAT3 UNC5C ASTN1 RIMBP2 ADGRV1 RYR3	1.92e-08	160	82	7	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	NRG1 LLGL2 IFT57 MYO1B ADGRV1 VEGFA	9.94e-07	179	82	6	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	normal-na-Lymphocytic_B-B_mem-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	TRAF5 IFT57 BLNK RIMBP2 CHD7 DNAH8	1.09e-06	182	82	6	ee36ea6cb9a5a08aeb83f2b7a249255f0b1a9870
ToppCell	COVID-19-lung-AT1\|lung / Disease (COVID-19 only), tissue and cell type	NRG1 LLGL2 IFT57 MYO1B ADGRV1 VEGFA	1.13e-06	183	82	6	942530449e9c6583705eeb8f6f12621daea57252
ToppCell	severe-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BLNK ZDBF2 CHD7 PNPLA7 FANCM DNAH8	1.59e-06	194	82	6	2fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCell	mild-B_memory\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRAF5 MIS18BP1 IFT57 BLNK CHD7 DNAH8	1.84e-06	199	82	6	e6ac9a0959b0de2c6a99298feb7715aa80ade1dd
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-B-B_memory\|COVID-19_Mild / Disease, condition lineage and cell class	TRAF5 IFT57 BLNK RELB CHD7 DNAH8	1.84e-06	199	82	6	54e392b4ebe601d4838739ff7de3ac6b2203c948
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-CD45____B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASA3 BLNK PKN1 PLEKHM3 DNAH8	1.57e-05	170	82	5	6210ee3bf29059e6149c047bb7e02c5f59441519
ToppCell	facs-Thymus-Flowthrough-3m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAVCR2 TRAF5 ZNF451 BLNK PLEKHM3	1.66e-05	172	82	5	356a66cd9303470e427005cc67fdd22a2c4bf971
ToppCell	facs-Thymus-Flowthrough-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAVCR2 TRAF5 ZNF451 BLNK PLEKHM3	1.66e-05	172	82	5	46fadeee483fdf8402df92ec98575a09c6c15b16
ToppCell	facs-Thymus-Flowthrough-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAVCR2 TRAF5 ZNF451 BLNK PLEKHM3	1.66e-05	172	82	5	438d2e7f1897668a14d85ca70722e5d0102606dc
ToppCell	AT1_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	NRG1 LLGL2 MYO1B RELB VEGFA	1.70e-05	173	82	5	b29816427428c7053017477f59b828bf1357f3b2
ToppCell	COVID-19_Moderate-B_memory\|World / disease group, cell group and cell class	TRAF5 IFT57 BLNK CHD7 DNAH8	2.06e-05	180	82	5	2f37187b866edb56410c2334b72713f2248dc335
ToppCell	COVID-19_Moderate-B_memory\|COVID-19_Moderate / disease group, cell group and cell class	TRAF5 IFT57 BLNK CHD7 DNAH8	2.17e-05	182	82	5	bbdbef62389ac062118cc0c7979686393399f2c8
ToppCell	COVID-19-lung-AT1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRG1 LLGL2 IFT57 MYO1B ADGRV1	2.23e-05	183	82	5	7b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell	droplet-Heart-4Chambers-21m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKD2 ARAP3 APLP2 PLXND1 NOTCH1	2.29e-05	184	82	5	f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCell	Healthy/Control-B_memory\|World / Disease group and Cell class	TRAF5 IFT57 BLNK CHD7 DNAH8	2.29e-05	184	82	5	9e1879d86b535ede9b47deb0752e291f987a5d5e
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRAF5 MIS18BP1 IFT57 BLNK DNAH8	2.35e-05	185	82	5	91c9a3ea1afd97d35bd05648875d29b35fe09128
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MIS18BP1 CKAP5 CLSPN DDX39A CNDP1	2.35e-05	185	82	5	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	NRG1 LLGL2 IFT57 MYO1B VEGFA	2.41e-05	186	82	5	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	Healthy_donor-B_memory\|World / disease group, cell group and cell class (v2)	TRAF5 IFT57 BLNK CHD7 DNAH8	2.48e-05	187	82	5	4f68e3243071a4549c80aff8bff32c6ad892ee7f
ToppCell	Control-Lymphoid_B-B_memory\|Control / Disease group, lineage and cell class	TRAF5 IFT57 BLNK CHD7 DNAH8	2.54e-05	188	82	5	ba4245de3bee29118abab57c4fce60b2007a189c
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRAF5 IFT57 BLNK CHD7 DNAH8	2.54e-05	188	82	5	cd833a125a5279ac32a9a9cb9ecd05ae24bea3a9
ToppCell	Healthy/Control-B_memory\|Healthy/Control / Disease group and Cell class	TRAF5 IFT57 BLNK CHD7 DNAH8	2.54e-05	188	82	5	3aff07f77b2b15e7a30e47b30115178abe64474e
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRAF5 IFT57 BLNK CHD7 DNAH8	2.54e-05	188	82	5	9256c5f45c97df209bb9c322c3b557d4f726a333
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LLGL2 COL14A1 RIMBP2 ADGRV1 RYR3	2.60e-05	189	82	5	e059be2965cca70ff5576df055d0af1775b76e00
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRAF5 IFT57 BLNK CHD7 DNAH8	2.60e-05	189	82	5	ac0203f17b481d608587113ea2de0f383b29ed27
ToppCell	Healthy_donor-B_memory\|Healthy_donor / disease group, cell group and cell class (v2)	TRAF5 IFT57 BLNK CHD7 DNAH8	2.67e-05	190	82	5	46104a521f00d399315deca86699cb261b2795d6
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	TRAF5 IFT57 BLNK CHD7 DNAH8	2.74e-05	191	82	5	03f6da73e7b706252d2096507222229c4101a27b
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TRAF5 IFT57 BLNK CHD7 DNAH8	2.74e-05	191	82	5	578b58782e816ecaeabfbc616ceb1dcd53ee428b
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRAF5 IFT57 BLNK CHD7 DNAH8	2.74e-05	191	82	5	22134a2c1a92208bc1629a620ce73a56502613c2
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	LLGL2 IFT57 PPP1R13B MYO1B ADGRV1	2.74e-05	191	82	5	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TRAF5 IFT57 BLNK CHD7 DNAH8	2.81e-05	192	82	5	debd471f61cf3606b8e9c246add0be5df601af7f
ToppCell	control-B_memory\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRAF5 IFT57 BLNK CHD7 DNAH8	2.81e-05	192	82	5	d6ef271b6c4f9b49323650f3f773abd61c1b13c3
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 PPP1R13B APLP2 NOTCH1 VEGFA	2.81e-05	192	82	5	4bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	LLGL2 PPP1R13B MYO1B ADGRV1 DENND2B	2.81e-05	192	82	5	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	COVID-19_Mild-Lymphoid_B-B_memory\|COVID-19_Mild / Disease group, lineage and cell class	TRAF5 IFT57 BLNK CHD7 DNAH8	2.81e-05	192	82	5	d27db7669de95bddbea8ccb83e6f10ae7240b1ab
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TRAF5 IFT57 BLNK CHD7 DNAH8	2.81e-05	192	82	5	314f74dd3c6d94839eed05b9a1a398217ef78029
ToppCell	(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells\|(1)_Control_(PBS) / Stress and Cell class	PRKD2 RGL1 ARAP3 PLXND1 NOTCH1	2.81e-05	192	82	5	e16e49b302019474232ef4cc0ff217d33afe34cf
ToppCell	Control-Myeloid-MoAM5,_CCL3L1\|Control / Condition, Lineage and Cell class	RGL1 NRG1 RELB CMKLR1 VEGFA	2.95e-05	194	82	5	a1dd264822de83a0ffaf89ca4707c6a76809359e
ToppCell	facs-Heart-LA-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKD2 ARAP3 PPP1R13B APLP2 NOTCH1	2.95e-05	194	82	5	33cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TRAF5 IFT57 BLNK CHD7 DNAH8	3.02e-05	195	82	5	51e6cfecd66a874673d0b79a295489a358bddfd5
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NRG1 LLGL2 IFT57 MYO1B VEGFA	3.02e-05	195	82	5	a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RGL1 PRAM1 NRG1 CMKLR1 VEGFA	3.02e-05	195	82	5	403d874198a7bde626b0d0b4efad8dbb34060761
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NRG1 LLGL2 MYO1B APLP2 VEGFA	3.10e-05	196	82	5	6731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCell	severe_COVID-19-B_memory\|severe_COVID-19 / disease group, cell group and cell class (v2)	TRAF5 IFT57 BLNK CHD7 DNAH8	3.10e-05	196	82	5	c6e00cb59a88b9903cca233cefe05f80c5ea4153
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NRG1 LLGL2 MYO1B APLP2 VEGFA	3.10e-05	196	82	5	6856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRG1 FAT3 UNC5C RYR3 VEGFA	3.18e-05	197	82	5	467e7cbf511d3bcc701923603032aaf0bba2736d
ToppCell	Non-neuronal-Dividing-IPC-IPC-new\|World / Primary Cells by Cluster	DUT CHD7 ADGRV1 CLSPN NOTCH1	3.25e-05	198	82	5	11d2d4d179bc31ef2897d7ceeaf9bed1b20cbdc0
ToppCell	Non-neuronal-Dividing-IPC-IPC-new-9\|World / Primary Cells by Cluster	DUT CHD7 ADGRV1 CLSPN NOTCH1	3.25e-05	198	82	5	c724ef958e14e17a7d8c02b9f842510c0780f635
ToppCell	NS-moderate-d_16-33-Myeloid-Non-resident_Macrophage\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	HAVCR2 RGL1 NRG1 CMKLR1 PLXND1	3.25e-05	198	82	5	11a7a553de6786c1e8288251ba0d5c898505c158
ToppCell	(5)_Dendritic_cell-(52)_cycling_DCs\|(5)_Dendritic_cell / shred on Cell_type and subtype	RGL1 NRG1 CKAP5 APLP2 CLSPN	3.33e-05	199	82	5	d0ff446a197062b10f37b585f3f8716d6d89e5b7
ToppCell	Control-Control-Lymphocyte-B-B_memory\|Control / Disease, condition lineage and cell class	TRAF5 IFT57 BLNK CHD7 DNAH8	3.33e-05	199	82	5	76976d5f79f324a6c488161847c50f207361d6c6
ToppCell	mild-B_memory\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRAF5 IFT57 BLNK CHD7 DNAH8	3.33e-05	199	82	5	025bb65629d9e20c374e8f1ba08c36d1bb569190
ToppCell	mild-B_intermediate\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRAF5 IFT57 BLNK CHD7 DNAH8	3.41e-05	200	82	5	fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2\|World / Primary Cells by Cluster	MIS18BP1 DUT CHD7 ADGRV1 CLSPN	3.41e-05	200	82	5	4923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCell	mild-B_intermediate\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRAF5 IFT57 BLNK CHD7 DNAH8	3.41e-05	200	82	5	8e3132a1fe3708f725c5c4077878fb87bbea3678
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2-5\|World / Primary Cells by Cluster	MIS18BP1 DUT CHD7 ADGRV1 CLSPN	3.41e-05	200	82	5	dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D231\|Adult / Lineage, Cell type, age group and donor	LLGL2 PPP1R13B MYO1B ADGRV1	1.04e-04	132	82	4	8d30b71776f5f6da55dc78e0c5cb27be460004e3
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRAM1 BLNK POLR3A CNDP1	1.23e-04	138	82	4	611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH10 BLNK ZNF215 DNAH8	1.61e-04	148	82	4	6ffa212f0cc44c40d2143816dc6cfd82fbf09a33
ToppCell	normal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	UBR1 PRKD2 PANK3 ZDBF2	1.65e-04	149	82	4	a34d095b8e0fe59d69d84e4fd2fe4ccb82f92e4f
ToppCell	IIH-CD8-exh_CD4\|IIH / Condition, Cell_class and T cell subcluster	ARAP3 PLEKHM3 ADGRV1 SPDYE16	1.88e-04	154	82	4	a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DNAH10 FAT3 MYO1B PLXND1	2.02e-04	157	82	4	5aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCell	Control-B_naive-12\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HAVCR2 MYO1B CMKLR1 SPDYE16	2.02e-04	157	82	4	4803f601c1ba43260aa09172acc7964aac2c8ccf
ToppCell	Control-B_naive-12\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HAVCR2 MYO1B CMKLR1 SPDYE16	2.07e-04	158	82	4	41318f864770370ce77ed3fa4a84f76c0c22c482
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT3 UNC5C COL14A1 PNPLA7	2.07e-04	158	82	4	e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKD2 DUT BLNK PRIMPOL	2.12e-04	159	82	4	74655c22e9fdd88e3052b9dfb954c8fb678bd2d8
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COL14A1 CMKLR1 RYR3 POLR3A	2.33e-04	163	82	4	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HAVCR2 PRAM1 VPS13D GPATCH3	2.44e-04	165	82	4	94a5211072464fc24592bb107a853ce832e816fe
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CMKLR1 PLXND1 NOTCH1 VEGFA	2.50e-04	166	82	4	7a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VPS13D CLSPN DENND2B GRAMD4	2.50e-04	166	82	4	9fd9de82f98b9acdaa59ac98fb9664161514aec0
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	RGL1 JADE2 FAT3 COL14A1	2.50e-04	166	82	4	65dafed953b01a9830b54309af75c7a561e88336
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CMKLR1 PLXND1 NOTCH1 VEGFA	2.50e-04	166	82	4	bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Control / Condition, Lineage and Cell class	RGL1 SAMD9 ARAP3 CMKLR1	2.56e-04	167	82	4	ab6029ba037b6a499da8758864c44e174cde5587
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Myeloid / Condition, Lineage and Cell class	RGL1 SAMD9 ARAP3 CMKLR1	2.56e-04	167	82	4	6e5140527437193f441ca96893b9a00d346614f3
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	RGL1 ARAP3 ZFTA PLXND1	2.61e-04	168	82	4	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MIS18BP1 ARAP3 PLXND1 CLSPN	2.61e-04	168	82	4	37249f38f8f04ec5743097259de67b106ca2b02f
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NRG1 LLGL2 PLEKHM3 VEGFA	2.67e-04	169	82	4	cd16e8462ee09877be962fbd9a3badcb825820b0
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 FAT3 ADGRV1 RYR3	2.67e-04	169	82	4	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	HAVCR2 RGL1 RELB PLXND1	2.74e-04	170	82	4	9ac1ef57f14418a5dd2aa16861c3df698c28f5ed
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NRG1 UNC5C COL14A1 PLXND1	2.74e-04	170	82	4	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	NRG1 MYO1B ADGRV1 VEGFA	2.74e-04	170	82	4	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DHX16 MIS18BP1 DUT CLSPN	2.86e-04	172	82	4	1171e754fd503a0c1152162fcc12a115088a08c7
ToppCell	severe_influenza-B_memory\|World / disease group, cell group and cell class (v2)	TRAF5 IFT57 BLNK CHD7	2.86e-04	172	82	4	0ff38f9431cec73250c580a6010cb7891a3fe3f1
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IFT57 BLNK MYO1B CHD7	2.86e-04	172	82	4	62ed3b70fa1f6c84ea80ff00f60d2562be292e9d
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MIS18BP1 DUT CKAP5 CLSPN	2.86e-04	172	82	4	2b6cd84c946b1e800caba452ae70145ea285fec1
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BAZ1B CLSPN DNAH8 NOTCH1	2.92e-04	173	82	4	a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BAZ1B CLSPN DNAH8 NOTCH1	2.92e-04	173	82	4	639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell	Influenza_Severe-B_intermediate\|Influenza_Severe / Disease group and Cell class	IFT57 BLNK CHD7 DNAH8	2.99e-04	174	82	4	4276bdaac53aebd3084323a90ecde572d3177446
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HAVCR2 TDRKH DUT CLSPN	2.99e-04	174	82	4	09b091e24317c3f7bac043f04762a533e30793de
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HAVCR2 MIS18BP1 DUT CLSPN	3.05e-04	175	82	4	a6913f992a1ea20b43e5adeca3ede3a6fda820ad
ToppCell	Club-club-15\|World / Class top	RGL1 MIS18BP1 RELB CLSPN	3.05e-04	175	82	4	ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCell	AT1-AT2_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	NRG1 LLGL2 PPP1R13B VEGFA	3.05e-04	175	82	4	bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCell	NS-moderate-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	BLNK APLP1 RIMBP2 CNDP1	3.05e-04	175	82	4	a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MIS18BP1 P3H3 CKAP5 MYO1B	3.05e-04	175	82	4	3e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCell	droplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFT57 RELB CHD7 PLXND1	3.12e-04	176	82	4	24b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDCD2 PANK3 ZNF451 HSF2	3.12e-04	176	82	4	dca70f309af24421f8dc708cbd88512814b8e79e
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MIS18BP1 ARAP3 CKAP5 PPP1R13B	3.12e-04	176	82	4	8385435074cc5235b7af7424974f609388fc2cff
Drug	Bepridil hydrochloride [74764-40-2]; Up 200; 10uM; MCF7; HT_HG-U133A	GPATCH3 BLNK BAZ1B APLP1 RELB CEP164 VEGFA	4.79e-06	190	80	7	2629_UP
Drug	Aminophylline [317-34-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A	TDRKH VPS13D RASA3 MYO1B APLP2 CEP164 NOTCH1	5.88e-06	196	80	7	3374_DN
Disease	orofaciodigital syndrome (is_implicated_in)	C2CD3 IFT57	2.17e-05	3	80	2	DOID:4501 (is_implicated_in)
Disease	BMI-adjusted waist-hip ratio, physical activity measurement	DNAH10 BAZ1B PLXND1 VEGFA	3.79e-05	69	80	4	EFO_0007788, EFO_0008002
Disease	hyperuricemia	PRKD2 BAZ1B VEGFA	9.87e-05	33	80	3	EFO_0009104
Disease	Alzheimer's disease 1 (implicated_via_orthology)	APLP1 APLP2	1.51e-04	7	80	2	DOID:0080348 (implicated_via_orthology)
Disease	glomerulonephritis (is_implicated_in)	VEGFA CNDP1	3.93e-04	11	80	2	DOID:2921 (is_implicated_in)
Disease	Gastric ulcer	NRG1 VEGFA	1.08e-03	18	80	2	C0038358
Disease	smoking status measurement	B3GALT4 CUL3 SAMD9 IFT57 JADE2 FAT3 MYO1B CHD7 CMKLR1 DNAH8	1.15e-03	1160	80	10	EFO_0006527
Disease	body mass index, high density lipoprotein cholesterol measurement	DNAH10 VEGFA	1.20e-03	19	80	2	EFO_0004340, EFO_0004612
Disease	DiGeorge syndrome (implicated_via_orthology)	PLXND1 VEGFA	1.20e-03	19	80	2	DOID:11198 (implicated_via_orthology)
Disease	triglyceride measurement, body mass index	DNAH10 VEGFA	1.20e-03	19	80	2	EFO_0004340, EFO_0004530
Disease	triglyceride measurement, body fat percentage	DNAH10 VEGFA	1.47e-03	21	80	2	EFO_0004530, EFO_0007800
Disease	hepatocellular carcinoma (is_implicated_in)	HAVCR2 CEP164 RYR3 VEGFA	1.51e-03	181	80	4	DOID:684 (is_implicated_in)
Disease	hematocrit	NRG1 TDRKH JADE2 PPP1R13B ADGRV1 DENND2B CEP164 TFR2 VEGFA	1.65e-03	1011	80	9	EFO_0004348
Disease	congenital heart disease (is_implicated_in)	NOTCH1 VEGFA	1.93e-03	24	80	2	DOID:1682 (is_implicated_in)
Disease	Carcinoma, Pancreatic Ductal	NOTCH1 VEGFA	1.93e-03	24	80	2	C0887833
Disease	body fat percentage, high density lipoprotein cholesterol measurement	DNAH10 VEGFA	2.09e-03	25	80	2	EFO_0004612, EFO_0007800
Disease	apolipoprotein B measurement	CARM1 HAVCR2 DNAH10 BAZ1B RELB TFR2 VEGFA	2.16e-03	663	80	7	EFO_0004615
Disease	brain cancer (implicated_via_orthology)	LLGL2 NOTCH1	2.26e-03	26	80	2	DOID:1319 (implicated_via_orthology)
Disease	diastolic blood pressure, systolic blood pressure	RGL1 NRG1 C2CD3 RBM33 DUT DENND2B CEP164	2.29e-03	670	80	7	EFO_0006335, EFO_0006336
Disease	total cholesterol measurement, intermediate density lipoprotein measurement	BAZ1B RELB TFR2	2.50e-03	99	80	3	EFO_0004574, EFO_0008595

Protein segments in the cluster

Peptide	Gene	Start	Entry
SVEEQEELEEPVYEE	ARAP3	1391	Q8WWN8
EELEEPVYEEPVYEE	ARAP3	1396	Q8WWN8
AELPEEIDISTYIEQ	DDX39A	411	O00148
EPVTRDEAEDYYDVI	BAZ1B	1366	Q9UIG0
EEEPAEFQIDDTYSV	GTPBP1	391	O00178
EYVEDFRFQPEENTV	GRAMD4	176	Q6IC98
DDVYVNVPELVSELV	B3GALT4	176	O96024
DDVPELEEYFLVNLT	ADGRV1	2911	Q8WXG9
IYPHEEIEVEETFII	ADGRV1	4596	Q8WXG9
DEVPEIEEDYVIQLV	ADGRV1	4721	Q8WXG9
YFVEPPQAEEEEETV	APLP1	256	P51693
EFEDTEENKLIYTPI	ARL2BP	51	Q9Y2Y0
PKYQLVLEEEETIEF	DHX16	351	O60231
EQRVEQYLEELPDTE	DENND2B	1101	P78524
EIEDELFNPDYVEVD	CHD7	871	Q9P2D1
FDLVQRIIYEVEDPS	PPP1R13B	901	Q96KQ4
VDDLENTELPYFVLE	ASTN1	81	O14525
EYVEEPEEEQLYTDE	RBM33	161	Q96EV2
PEEEQLYTDEVLDIE	RBM33	166	Q96EV2
EQEEYSTFVIDDPQE	RASA3	761	Q14644
DPAEEYELVQVISED	RGL1	691	Q9NZL6
YEDLEIVEPVTVNVF	RELB	366	Q01201
IENVLSVLLFYPEDE	P3H3	336	Q8IVL6
PLRIVEDEEYETTQE	NRG1	516	Q02297
PLDFEEVERYTINIE	PCDHGB7	306	Q9Y5F8
PLDFEAIETYDIDIQ	PCDHB1	306	Q9Y5F3
PYVAQEIQEEIDELL	APLP2	551	Q06481
EEEEDAPAVISDFIY	NOTCH1	1901	P46531
ILEPETEESENEFYI	MIS18BP1	816	Q6P0N0
AYVEIEYEQETEPVA	MAK16	281	Q9BXY0
TFDDPYALVVLAEEE	LLGL2	346	Q6P1M3
LPFEEELYIVRTDDQ	FANCM	961	Q8IYD8
VDEYFRQPVVDTFDI	CARM1	331	Q86X55
EEDFYELVEPAEVAE	JADE2	401	Q9NQC1
PFEYEDSETVEQEEL	GPATCH3	236	Q96I76
NFLFPEFEIVIETED	PDCD2	186	Q16342
YADEVAVAEELLDPE	PLXND1	1146	Q9Y4D7
DTINEETVELLQPYF	DNAH8	3236	Q96JB1
ELFESPVYLEEAADV	INTS2	166	Q9H0H0
ENVDIATVYQIFPDE	PRKD2	541	Q9BZL6
EPDIIEQLVEFAYTA	KLHL7	91	Q8IXQ5
EFLEYVYEEPLIDIQ	PLEKHM3	571	Q6ZWE6
FYPEIEEVQALDDTE	DUT	226	P33316
QTEYEEELLDVPRDA	PNPLA7	1261	Q6ZV29
SYFEPIDITAEEEQE	PANK3	26	Q9H999
EVPQIDAYELLEAVE	CKAP5	261	Q14008
PIYPVEELEEESVAE	IFT57	166	Q9NWB7
LLEDEADYVVPVEDN	BLNK	171	Q8WV28
DEDYEEDIIEPRTLN	C2CD3	2061	Q4AC94
TEEVPAQQYLEIDEV	COL14A1	621	Q05707
YTFEEIQQETDIPER	CUL3	611	Q13618
PFDREEQELYELVVE	FAT3	2041	Q8TDW7
EYFLEPEINLVTENT	CACNG7	76	P62955
EEPEDYELLQILSDD	RALGDS	841	Q12967
YEEELDVPLVLFNEV	DYNC1H1	2901	Q14204
YPLVGEETEREEEEE	DCAF8L1	91	A6NGE4
FRDVDEYIDPVIDNV	DNAH10	3481	Q8IVF4
IDEGDEVILIVPFYD	KYAT3	146	Q6YP21
SYNSEVDEIPDELII	PRIMPOL	541	Q96LW4
YPDIVIVEDDNEDEY	HSF2	281	Q03933
IVEDDNEDEYAPVIQ	HSF2	286	Q03933
SNFLEEVPDDVEVYL	RIMBP2	1011	O15034
YVPVLLLVDDFEEQD	SAMD9	791	Q5K651
TIEENVYEVEEPNEY	HAVCR2	266	Q8TDQ0
EDIPQVPDEIYELYD	PRAM1	496	Q96QH2
GEISEYIEEVFLPDD	POLR3A	1111	O14802
EEVFDSIVNDEVRYP	PKN1	821	Q16512
DFEPSIEYQFVERLE	TRAF5	26	O00463
QLVLEEDYDETYIPS	CEP164	11	Q9UPV0
EDYDETYIPSEQEIL	CEP164	16	Q9UPV0
DEYPDYLDSIVVLED	CMKLR1	16	Q99788
YDEVVPLTEEEINTY	CNDP1	296	Q96KN2
IDEYEEDVIDEVLPS	CLSPN	1076	Q9HAW4
DVEIEYVTEEPEIYE	SF3B2	366	Q13435
YQNIEEEIVELPDLD	ZNF451	866	Q9Y4E5
YAIELPEDIEENRAV	TDRKH	491	Q9Y2W6
YKVTEEPLEEETEDV	RYR3	4431	Q15413
VSREELEEIQAYDPE	SPDYE16	286	A6NNV3
VSREELEEIQAYDPE	SPDYE18	326	P0DV79
NQLVIYEEIRDPEED	SSX8P	171	Q7RTT4
VIDQPEVAVYEEETV	ZDBF2	801	Q9HCK1
SFEDFQVEVLVEYPL	UBR1	636	Q8IWV7
QEAFIPETIYTEEED	ZNF215	286	Q9UL58
ETLVDIFQEYPDEIE	VEGFA	56	P15692
DIIDPVEDRNFYITI	UNC5C	206	O95185
LVVSEDVNYEPDLDF	TFR2	116	Q9UP52
FTPEERQTILEAYEE	ZFTA	631	C9JLR9
RSYEVDELPVTEQEL	VPS13D	3801	Q5THJ4
VLFNELEIPVEEYSF	MYO1B	666	O43795