Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	tubulin binding	MAPRE3 GAS2L3 MAP6 FMN1 WIPF3 APC INO80 CAMSAP2 CLIP1	8.52e-06	428	64	9	GO:0015631
GeneOntologyMolecularFunction	cytoskeletal protein binding	MAPRE3 GAS2L3 MAP6 FMN1 SGK1 CAMK2D INPPL1 CLTC WIPF3 APC INO80 CAMSAP2 CLIP1	3.77e-05	1099	64	13	GO:0008092
GeneOntologyMolecularFunction	microtubule plus-end binding	MAPRE3 APC CLIP1	4.63e-05	22	64	3	GO:0051010
GeneOntologyMolecularFunction	microtubule binding	MAPRE3 GAS2L3 MAP6 FMN1 APC CAMSAP2 CLIP1	5.68e-05	308	64	7	GO:0008017
GeneOntologyMolecularFunction	SH3 domain binding	FMN1 INPPL1 WIPF3 ADAM12 SH3BGRL2	9.53e-05	143	64	5	GO:0017124
GeneOntologyMolecularFunction	protein domain specific binding	ARRB2 TJP1 FMN1 INPPL1 CLTC WIPF3 SYK NLGN1 ADAM12 SH3BGRL2	4.38e-04	875	64	10	GO:0019904
GeneOntologyMolecularFunction	transcription corepressor activity	YEATS2 SETD5 GON4L ARID5A NPAT	8.35e-04	229	64	5	GO:0003714
GeneOntologyBiologicalProcess	regulation of organelle organization	MAPRE3 CELSR1 ARRB2 MAP6 TJP1 FMN1 SGK1 CLTC APC HRG NLGN1 DZIP1 INO80 STOX1 CAMSAP2 CLIP1 INO80B	3.50e-07	1342	63	17	GO:0033043
GeneOntologyBiologicalProcess	regulation of microtubule cytoskeleton organization	MAPRE3 MAP6 SGK1 CLTC APC CAMSAP2 CLIP1	1.08e-06	176	63	7	GO:0070507
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	MAPRE3 CELSR1 MAP6 TJP1 FMN1 SGK1 CLTC APC HRG CAMSAP2 CLIP1	1.27e-06	579	63	11	GO:0051493
GeneOntologyBiologicalProcess	regulation of microtubule polymerization	MAPRE3 SGK1 APC CAMSAP2 CLIP1	2.19e-06	69	63	5	GO:0031113
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	FSIP2 MAPRE3 GAS2L3 MAP6 SGK1 CLTC APC DZIP1 INO80 CAMSAP2 CLIP1	1.02e-05	720	63	11	GO:0000226
GeneOntologyBiologicalProcess	regulation of microtubule polymerization or depolymerization	MAPRE3 SGK1 APC CAMSAP2 CLIP1	1.98e-05	108	63	5	GO:0031110
GeneOntologyBiologicalProcess	microtubule polymerization	MAPRE3 SGK1 APC CAMSAP2 CLIP1	2.91e-05	117	63	5	GO:0046785
GeneOntologyBiologicalProcess	regulation of microtubule-based process	MAPRE3 MAP6 SGK1 CLTC APC CAMSAP2 CLIP1	3.04e-05	293	63	7	GO:0032886
GeneOntologyBiologicalProcess	regulation of protein polymerization	MAPRE3 FMN1 SGK1 APC CAMSAP2 CLIP1	7.37e-05	231	63	6	GO:0032271
GeneOntologyBiologicalProcess	actin filament-based process	CELSR1 MYOM1 GAS2L3 TJP1 FMN1 CAMK2D INPPL1 PCLO WIPF3 GLIPR1L1 HRG	8.89e-05	912	63	11	GO:0030029
GeneOntologyBiologicalProcess	synaptic vesicle targeting	PCLO NLGN1	9.13e-05	5	63	2	GO:0016080
GeneOntologyBiologicalProcess	presynaptic active zone assembly	PCLO NLGN1	9.13e-05	5	63	2	GO:1904071
GeneOntologyBiologicalProcess	protein localization to organelle	GFY FSIP2 MAPRE3 NACA NPAP1 SYK APC NUP214 DZIP1 CHAMP1 STAT3 PYGO1	9.85e-05	1091	63	12	GO:0033365
GeneOntologyBiologicalProcess	regulation of protein-containing complex assembly	MAPRE3 FMN1 SGK1 SYK APC HRG CAMSAP2 CLIP1	1.16e-04	489	63	8	GO:0043254
GeneOntologyBiologicalProcess	supramolecular fiber organization	MAPRE3 MYOM1 GAS2L3 TJP1 FMN1 SGK1 INPPL1 WIPF3 APC CAMSAP2 CLIP1	1.36e-04	957	63	11	GO:0097435
GeneOntologyBiologicalProcess	microtubule polymerization or depolymerization	MAPRE3 SGK1 APC CAMSAP2 CLIP1	1.62e-04	168	63	5	GO:0031109
GeneOntologyBiologicalProcess	regulation of cellular component biogenesis	MAPRE3 SETD5 TJP1 FMN1 SGK1 SYK APC HRG NLGN1 DZIP1 CAMSAP2 CLIP1	2.21e-04	1189	63	12	GO:0044087
GeneOntologyBiologicalProcess	microtubule-based process	FSIP2 MAPRE3 GAS2L3 MAP6 SGK1 CLTC APC DZIP1 INO80 CAMSAP2 CLIP1	3.25e-04	1058	63	11	GO:0007017
GeneOntologyBiologicalProcess	cell cycle G1/S phase transition	USP26 CAMK2D APC INO80 STOX1 NPAT	3.39e-04	306	63	6	GO:0044843
GeneOntologyBiologicalProcess	circulatory system development	ARRB2 TJP1 GLI2 CAMK2D TMIGD2 NACA SYK MCAM APC HRG DZIP1 ADAM12 STAT3	3.51e-04	1442	63	13	GO:0072359
GeneOntologyBiologicalProcess	regulation of supramolecular fiber organization	MAPRE3 TJP1 FMN1 SGK1 APC CAMSAP2 CLIP1	3.68e-04	438	63	7	GO:1902903
GeneOntologyBiologicalProcess	presynaptic active zone organization	PCLO NLGN1	4.07e-04	10	63	2	GO:1990709
GeneOntologyBiologicalProcess	regulation of anatomical structure morphogenesis	CELSR1 MAP6 TJP1 SGK1 TMIGD2 APC HRG NLGN1 STOX1 ADAM12 STAT3	4.18e-04	1090	63	11	GO:0022603
GeneOntologyCellularComponent	nuclear body	UBN1 SGK1 GLI2 INPPL1 GON4L DZIP1 INO80 PHAX PPIH CHAMP1 INO80B NPAT	1.37e-05	903	63	12	GO:0016604
GeneOntologyCellularComponent	Ino80 complex	GON4L INO80 INO80B	1.72e-05	17	63	3	GO:0031011
GeneOntologyCellularComponent	INO80-type complex	GON4L INO80 INO80B	8.10e-05	28	63	3	GO:0097346
GeneOntologyCellularComponent	ribbon synapse	CAMK2D PCLO CLTC	1.22e-04	32	63	3	GO:0097470
GeneOntologyCellularComponent	protein complex involved in cell-cell adhesion	GLIPR1L1 NLGN1	1.33e-04	6	63	2	GO:0098635
GeneOntologyCellularComponent	microtubule	MAPRE3 GAS2L3 MAP6 CLTC APC INO80 CAMSAP2 CLIP1	1.91e-04	533	63	8	GO:0005874
GeneOntologyCellularComponent	microtubule end	MAPRE3 CAMSAP2 CLIP1	2.04e-04	38	63	3	GO:1990752
GeneOntologyCellularComponent	B cell receptor complex	TMIGD2 SYK	2.47e-04	8	63	2	GO:0019815
GeneOntologyCellularComponent	clathrin complex	CLTC AAK1	3.17e-04	9	63	2	GO:0071439
GeneOntologyCellularComponent	supramolecular fiber	MAPRE3 COL6A3 MYOM1 GAS2L3 MAP6 FMN1 CLTC APC INO80 CAMSAP2 CLIP1	7.22e-04	1179	63	11	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	MAPRE3 COL6A3 MYOM1 GAS2L3 MAP6 FMN1 CLTC APC INO80 CAMSAP2 CLIP1	7.63e-04	1187	63	11	GO:0099081
GeneOntologyCellularComponent	sperm head-tail coupling apparatus	FSIP2 GLIPR1L1	1.33e-03	18	63	2	GO:0120212
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	MAPRE3 GAS2L3 MAP6 FMN1 CLTC APC INO80 CAMSAP2 CLIP1	1.42e-03	899	63	9	GO:0099513
GeneOntologyCellularComponent	clathrin-coated pit	ARRB2 CLTC AAK1	1.82e-03	80	63	3	GO:0005905
Domain	-	MAPRE3 GAS2L3 CAMSAP2	1.70e-03	71	62	3	1.10.418.10
Domain	CH	MAPRE3 GAS2L3 CAMSAP2	1.84e-03	73	62	3	PS50021
Domain	CH-domain	MAPRE3 GAS2L3 CAMSAP2	1.98e-03	75	62	3	IPR001715
Domain	SH2	INPPL1 SYK STAT3	4.61e-03	101	62	3	PF00017
Domain	SH2	INPPL1 SYK STAT3	5.84e-03	110	62	3	SM00252
Domain	SH2	INPPL1 SYK STAT3	5.99e-03	111	62	3	PS50001
Domain	SH2	INPPL1 SYK STAT3	6.14e-03	112	62	3	IPR000980
Domain	-	INPPL1 SYK STAT3	6.14e-03	112	62	3	3.30.505.10
Pubmed	Human transcription factor protein interaction networks.	YEATS2 UBN1 GLI2 ZNF516 NACA ZFP91 GON4L NUP214 INO80 TEAD3 NOP2 INO80B STAT3 PYGO1 NPAT	5.57e-08	1429	66	15	35140242
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	YEATS2 UBN1 PAPOLA ZNF516 ZFP91 CLTC AAK1 NUP214 CHAMP1 NOP2 CLIP1	2.18e-07	774	66	11	15302935
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	TJP1 NACA CLTC MCAM APC NUP214 STAT3	5.80e-07	256	66	7	33397691
Pubmed	A dual role for planar cell polarity genes in ciliated cells.	MAPRE3 CELSR1 TJP1	1.07e-06	11	66	3	25024228
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	YEATS2 PAPOLA TJP1 NACA AAK1 NUP214 PHAX CHAMP1 NOP2 CAMSAP2 STAT3	1.38e-06	934	66	11	33916271
Pubmed	Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton.	GAS2L3 CAMK2D APC SH3BGRL2	2.16e-06	48	66	4	27872092
Pubmed	Cultured peripheral blood mast cells from chronic idiopathic urticaria patients spontaneously degranulate upon IgE sensitization: Relationship to expression of Syk and SHIP-2.	INPPL1 SYK	3.55e-06	2	66	2	19477690
Pubmed	Dynamic behavior of GFP-CLIP-170 reveals fast protein turnover on microtubule plus ends.	MAPRE3 CLIP1	3.55e-06	2	66	2	18283108
Pubmed	Identification of serum and glucocorticoid-regulated kinase 1 as a regulator of signal transducer and activator of transcription 3 signaling.	SGK1 STAT3	3.55e-06	2	66	2	35202674
Pubmed	STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress.	SYK STAT3	3.55e-06	2	66	2	20133729
Pubmed	Stat3 is a negative regulator of intestinal tumor progression in Apc(Min) mice.	APC STAT3	3.55e-06	2	66	2	19962983
Pubmed	STAT3 signaling maintains homeostasis through a barrier function and cell survival in corneal endothelial cells.	TJP1 STAT3	3.55e-06	2	66	2	30439348
Pubmed	Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC.	SGK1 APC	3.55e-06	2	66	2	19494170
Pubmed	Expanding Our Knowledge of Molecular Pathogenesis in Histiocytoses: Solitary Soft Tissue Histiocytomas in Children With a Novel CLTC::SYK Fusion.	CLTC SYK	3.55e-06	2	66	2	37522373
Pubmed	CaMKIIδ is upregulated by pro-inflammatory cytokine IL-6 in a JAK/STAT3-dependent manner to promote angiogenesis.	CAMK2D STAT3	3.55e-06	2	66	2	33749880
Pubmed	A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses.	APC STAT3	3.55e-06	2	66	2	19701202
Pubmed	INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis.	APC INO80	3.55e-06	2	66	2	29383140
Pubmed	Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound.	CLTC APC	3.55e-06	2	66	2	29769406
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	COL6A3 MYOM1 CLTC WIPF3 GON4L DZIP1 PHAX CLIP1	4.57e-06	497	66	8	23414517
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	GAS2L3 TJP1 NACA ZFP91 CLTC AAK1 PHAX PPIH NOP2 CLIP1 SH3BGRL2 STAT3	9.20e-06	1371	66	12	36244648
Pubmed	Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling.	ARRB2 APC	1.06e-05	3	66	2	22315403
Pubmed	Identification of new interacting partners of the shuttling protein ubinuclein (Ubn-1).	UBN1 TJP1	1.06e-05	3	66	2	22245583
Pubmed	Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APCMin/+ mice.	APC STAT3	1.06e-05	3	66	2	22461519
Pubmed	Stat3 is indispensable for damage-induced crypt regeneration but not for Wnt-driven intestinal tumorigenesis.	APC STAT3	1.06e-05	3	66	2	30156908
Pubmed	LncRNA PTCSC3 affects drug resistance of anaplastic thyroid cancer through STAT3/INO80 pathway.	INO80 STAT3	1.06e-05	3	66	2	29561707
Pubmed	Gas2l3, a novel constriction site-associated protein whose regulation is mediated by the APC/C Cdh1 complex.	GAS2L3 APC	1.06e-05	3	66	2	23469016
Pubmed	Mycobacterium bovis BCG promotes IL-10 expression by establishing a SYK/PKCα/β positive autoregulatory loop that sustains STAT3 activation.	SYK STAT3	1.06e-05	3	66	2	31175361
Pubmed	Signal transducer and activator of transcription 3 (STAT3) protein suppresses adenoma-to-carcinoma transition in Apcmin/+ mice via regulation of Snail-1 (SNAI) protein stability.	APC STAT3	1.06e-05	3	66	2	22496368
Pubmed	Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.	APC STAT3	1.06e-05	3	66	2	26364612
Pubmed	beta-Arrestin-dependent activation of Ca(2+)/calmodulin kinase II after beta(1)-adrenergic receptor stimulation.	ARRB2 CAMK2D	1.06e-05	3	66	2	20421423
Pubmed	Endothelial STAT3 Activation Increases Vascular Leakage Through Downregulating Tight Junction Proteins: Implications for Diabetic Retinopathy.	TJP1 STAT3	1.06e-05	3	66	2	27580405
Pubmed	MLKL inhibits intestinal tumorigenesis by suppressing STAT3 signaling pathway.	APC STAT3	1.06e-05	3	66	2	33767595
Pubmed	A conserved interaction that is essential for the biogenesis of histone locus bodies.	GON4L NPAT	1.06e-05	3	66	2	25339177
Pubmed	The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis.	ARRB2 CLTC	1.06e-05	3	66	2	10097102
Pubmed	Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3-mediated ZO-1 expression.	TJP1 STAT3	1.06e-05	3	66	2	36897043
Pubmed	Intestinal Epithelial Deletion of Sphk1 Prevents Colitis-Associated Cancer Development by Inhibition of Epithelial STAT3 Activation.	APC STAT3	1.06e-05	3	66	2	31776862
Pubmed	Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain.	ARRB2 CLTC	1.06e-05	3	66	2	9169477
Pubmed	Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.	CLTC APC	1.06e-05	3	66	2	15294912
Pubmed	Structural Analysis of the SANT/Myb Domain of FLASH and YARP Proteins and Their Complex with the C-Terminal Fragment of NPAT by NMR Spectroscopy and Computer Simulations.	GON4L NPAT	1.06e-05	3	66	2	32722282
Pubmed	Bacterial DNA promoting inflammation via the Sgk1/Nedd4L/Syk pathway in mast cells contributes to antihistamine-nonresponsive CSU.	SGK1 SYK	1.06e-05	3	66	2	36857592
Pubmed	APC sensitive gastric acid secretion.	SGK1 APC	1.06e-05	3	66	2	19255508
Pubmed	JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia.	APC STAT3	1.06e-05	3	66	2	22669242
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	YEATS2 SETD5 CLTC GON4L NUP214 NLGN1 CAMSAP2	1.23e-05	407	66	7	12693553
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MAP6 TJP1 CAMK2D ZNF516 CLTC AAK1 APC NOP2 CAMSAP2 CLIP1	1.31e-05	963	66	10	28671696
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	YEATS2 ARRB2 ZNF516 APC NUP214 CHAMP1 NPAT	1.46e-05	418	66	7	34709266
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	MAP6 CAMK2D PCLO CLTC AAK1 NLGN1	1.60e-05	281	66	6	28706196
Pubmed	ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.	CAMK2D ZNF516 ZNF185	1.64e-05	26	66	3	25228645
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	FSIP2 UBN1 ZFP91 INO80 PHAX CHAMP1 NOP2 NPAT	1.96e-05	608	66	8	36089195
Pubmed	Characterization of the ubinuclein protein as a new member of the nuclear and adhesion complex components (NACos).	UBN1 TJP1	2.12e-05	4	66	2	18823282
Pubmed	Sex differences in the relationship of IL-6 signaling to cancer cachexia progression.	APC STAT3	2.12e-05	4	66	2	25555992
Pubmed	Serum- and Glucocorticoid-Inducible Kinase 1 Promotes Alternative Macrophage Polarization and Restrains Inflammation through FoxO1 and STAT3 Signaling.	SGK1 STAT3	2.12e-05	4	66	2	34162726
Pubmed	Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration.	APC CLIP1	2.12e-05	4	66	2	15572129
Pubmed	CLEC12B Decreases Melanoma Proliferation by Repressing Signal Transducer and Activator of Transcription 3.	INPPL1 STAT3	2.12e-05	4	66	2	34310951
Pubmed	Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice.	APC STAT3	2.12e-05	4	66	2	21204268
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	YEATS2 UBN1 TJP1 ZNF185 AAK1 MCAM STAT3	2.15e-05	444	66	7	34795231
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FSIP2 TJP1 CAMK2D INPPL1 AAK1 APC DZIP1 CAMSAP2 STAT3	3.51e-05	861	66	9	36931259
Pubmed	Role of CLASP2 in microtubule stabilization and the regulation of persistent motility.	APC CLIP1	3.53e-05	5	66	2	17113391
Pubmed	Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis.	APC STAT3	3.53e-05	5	66	2	26880802
Pubmed	New mouse models for high resolution and live imaging of planar cell polarity proteins in vivo.	CELSR1 TJP1	3.53e-05	5	66	2	34463728
Pubmed	A requirement for membrane cholesterol in the beta-arrestin- and clathrin-dependent endocytosis of LPA1 lysophosphatidic acid receptors.	ARRB2 CLTC	3.53e-05	5	66	2	16263766
Pubmed	EB/RP gene family encodes tubulin binding proteins.	MAPRE3 APC	3.53e-05	5	66	2	10188731
Pubmed	The armadillo repeat domain of the APC tumor suppressor protein interacts with Striatin family members.	TJP1 APC	3.53e-05	5	66	2	18502210
Pubmed	Characterization of functional domains of human EB1 family proteins.	MAPRE3 APC	3.53e-05	5	66	2	14514668
Pubmed	MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM.	MCAM APC	3.53e-05	5	66	2	31690663
Pubmed	EB1 and EB3 control CLIP dissociation from the ends of growing microtubules.	MAPRE3 CLIP1	3.53e-05	5	66	2	16148041
Pubmed	Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models.	APC PYGO1	3.53e-05	5	66	2	30760710
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	PAPOLA GAS2L3 MAP6 SETD5 FMN1 CAMK2D CLTC APC INO80 NPAT	3.59e-05	1084	66	10	11544199
Pubmed	Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.	APC STAT3	5.29e-05	6	66	2	25270258
Pubmed	Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling.	TJP1 STAT3	5.29e-05	6	66	2	27132469
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	YEATS2 NACA ZFP91 CLTC NUP214 CHAMP1	6.07e-05	357	66	6	37059091
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	ARRB2 TJP1 NACA CLTC APC NUP214 PPIH CHAMP1 NOP2 CLIP1	6.12e-05	1155	66	10	20360068
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF516 NACA AAK1 DZIP1 INO80 ERI2 CHAMP1	6.49e-05	529	66	7	14621295
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MAPRE3 MAP6 TJP1 CAMK2D PCLO ZNF185 CLTC AAK1 APC HRG CAMSAP2	7.38e-05	1431	66	11	37142655
Pubmed	GRK2-mediated receptor phosphorylation and Mdm2-mediated β-arrestin2 ubiquitination drive clathrin-mediated endocytosis of G protein-coupled receptors.	ARRB2 CLTC	7.40e-05	7	66	2	32962859
Pubmed	PCP auto count: a novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting.	CELSR1 TJP1	7.40e-05	7	66	2	38827526
Pubmed	Flattop regulates basal body docking and positioning in mono- and multiciliated cells.	CELSR1 TJP1	7.40e-05	7	66	2	25296022
Pubmed	CD146 coordinates brain endothelial cell-pericyte communication for blood-brain barrier development.	TJP1 MCAM	7.40e-05	7	66	2	28827364
Pubmed	Physical proximity and functional cooperation of glycoprotein 130 and glycoprotein VI in platelet membrane lipid rafts.	SYK STAT3	7.40e-05	7	66	2	31145836
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	YEATS2 UBN1 TJP1 CLTC NUP214 CHAMP1 NOP2 INO80B NPAT	7.72e-05	954	66	9	36373674
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	TJP1 CAMK2D ZFP91 GON4L INO80 CHAMP1	1.04e-04	394	66	6	27248496
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	YEATS2 PCLO NACA HRG INO80 CLIP1	1.07e-04	396	66	6	26687479
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CELSR1 SETD5 NACA ZFP91 AAK1 APC GON4L INO80 CAMSAP2 INTS8 INO80B	1.10e-04	1497	66	11	31527615
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	PAPOLA TJP1 CAMK2D INPPL1 CLTC APC NUP214 TEAD3 CAMSAP2 NFU1	1.15e-04	1247	66	10	27684187
Pubmed	SAP-1 is a microvillus-specific protein tyrosine phosphatase that modulates intestinal tumorigenesis.	TJP1 APC	1.27e-04	9	66	2	19170756
Pubmed	Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation.	SYK STAT3	1.58e-04	10	66	2	10825200
Pubmed	EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis.	MAPRE3 APC	1.58e-04	10	66	2	23001180
Pubmed	Regulation of arrestin-3 phosphorylation by casein kinase II.	ARRB2 CLTC	1.58e-04	10	66	2	11877451
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	ARRB2 UBN1 GLI2 INPPL1 CLTC NUP214	1.68e-04	430	66	6	35044719
Pubmed	CHIP-MYTH: a novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β₂-adrenergic receptor.	ARRB2 MCAM STAT3	1.68e-04	56	66	3	24561123
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	MAP6 CAMK2D CLTC CAMSAP2	1.80e-04	147	66	4	16959763
Pubmed	Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure.	TJP1 GLI2	1.93e-04	11	66	2	33103996
Pubmed	Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.	APC STAT3	1.93e-04	11	66	2	29398651
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ARRB2 UBN1 CAMK2D NACA ZNF185 CLTC AAK1 NUP214 PPIH NOP2	2.23e-04	1353	66	10	29467282
Pubmed	Microtubules enable the planar cell polarity of airway cilia.	CELSR1 TJP1	2.31e-04	12	66	2	23122850
Pubmed	Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development.	CELSR1 TJP1	2.31e-04	12	66	2	11891983
Pubmed	EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.	MAPRE3 CLTC APC	2.39e-04	63	66	3	29162697
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	ARRB2 TJP1 NACA CLTC NUP214 PPIH NOP2	2.54e-04	660	66	7	32780723
Pubmed	Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles.	CELSR1 TJP1	2.73e-04	13	66	2	18849982
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	YEATS2 NACA ZFP91 PHAX CHAMP1 CLIP1	2.76e-04	472	66	6	38943005
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	FMN1 CAMK2D APC NUP214 INO80 NOP2	2.86e-04	475	66	6	31040226
GeneFamily	INO80 complex \|SRCAP complex	INO80 INO80B	3.98e-04	15	36	2	595
GeneFamily	SH2 domain containing	INPPL1 SYK STAT3	1.06e-03	101	36	3	741
GeneFamily	PHD finger proteins	PHF21B PYGO1	1.38e-02	90	36	2	88
CoexpressionAtlas	DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_500	ZFP91 APC NUP214 INO80 CAMSAP2 INTS8	1.40e-07	78	65	6	gudmap_developingKidney_e15.5_Cap mesenchyme_500_k5
CoexpressionAtlas	DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_1000	ZFP91 APC NUP214 INO80 CAMSAP2 INTS8	5.64e-06	146	65	6	gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k5
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000	ZFP91 APC GON4L NUP214 INO80 CAMSAP2 INTS8	1.48e-05	261	65	7	gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#3	CELSR1 ARRB2 GAS2L3 PHAX PPIH CHAMP1 PRSS36	4.45e-05	310	65	7	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K3
ToppCell	Fetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARRB2 GAS2L3 FMN1 SGK1 SYK PRSS36	4.23e-07	193	66	6	2d0dd2671ff27b922eb316f1ed0140353536ef30
ToppCell	Mild-MAIT\|Mild / Disease group and Cell class	TMIGD2 MCAM TEAD3 ADAM12 SH3BGRL2	4.13e-06	161	66	5	0c1a04485708d5302600cdc2d7dac1cb76b4033a
ToppCell	Mild-MAIT\|World / Disease group and Cell class	TMIGD2 MCAM TEAD3 ADAM12 SH3BGRL2	4.52e-06	164	66	5	21dc02997dfae73cf70ce291661928526605dba1
ToppCell	lymphoid-T_cell\|lymphoid / Lineage, cell class and subclass	ARRB2 SGK1 TMIGD2 NACA AAK1	1.13e-05	198	66	5	41573038b34803f664a7cb5a7d05b8afdff55b58
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 GAS2L3 FMN1 SGK1 SYK	1.18e-05	200	66	5	78d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCell	Myeloid-Myeloid-C_(Cd16+_Monocyte)\|Myeloid / shred on cell class and cell subclass (v4)	CAMK2D WIPF3 NLGN1 CLIP1	2.76e-05	117	66	4	d1936e76a935216783a73ab414e4147fa48e68eb
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CELSR1 STOX1 TEAD3 SH3BGRL2	6.91e-05	148	66	4	1d9fa6b2ee9feaed39c63d44e638b5c0942d947c
ToppCell	368C-Lymphocytic-NK_cells\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TMIGD2 PCLO WIPF3 PRSS36	7.28e-05	150	66	4	17b3ac5ddc47b9cba0a27b268d63a6e491b2b111
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	CELSR1 STOX1 TEAD3 SH3BGRL2	7.28e-05	150	66	4	98fdc6bdfde84d680e11d8727502b79afbf64303
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 GLI2 TEAD3 ADAM12	9.58e-05	161	66	4	a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 GLI2 TEAD3 ADAM12	9.58e-05	161	66	4	08920a716f6ec62538e361211455a30ad726d7be
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 PCLO NLGN1 PKHD1L1	1.15e-04	169	66	4	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	MYOM1 GAS2L3 FMN1 SYK	1.18e-04	170	66	4	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	wk_20-22-Hematologic-Meg-ery-Megakaryocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MYOM1 ZNF185 PKHD1L1 SH3BGRL2	1.18e-04	170	66	4	eace4dd09cdbde0fa40a6aa0f3dba1114d0ce475
ToppCell	Healthy_donor-MAIT\|World / disease group, cell group and cell class (v2)	TMIGD2 WIPF3 MCAM ADAM12	1.24e-04	172	66	4	6524eb2be1c78700ad367e62624a4d7eb48b54f0
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	TMIGD2 NPAP1 WIPF3 GLIPR1L1	1.24e-04	172	66	4	980e8b9e1ceeb0dec9eb9ef95c139e5ffe99b6e4
ToppCell	Healthy/Control-MAIT\|Healthy/Control / Disease group and Cell class	TMIGD2 WIPF3 MCAM ADAM12	1.26e-04	173	66	4	56247c1e07477a8922fe2e3950ae05e2217fd77c
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MAP6 ZNF185 WIPF3 PHF21B	1.32e-04	175	66	4	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 PCLO WIPF3 PKHD1L1	1.32e-04	175	66	4	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	metastatic_Brain-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	MYOM1 FMN1 TMIGD2 STOX1	1.38e-04	177	66	4	43e1d0d3cf8f0c02e67d91f8dd1761df23d59e07
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL6A3 TEAD3 CAMSAP2 PHF21B	1.44e-04	179	66	4	98c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAP6 TJP1 WIPF3 PHF21B	1.50e-04	181	66	4	5bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAP6 TJP1 WIPF3 PHF21B	1.50e-04	181	66	4	8e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell	Healthy_donor-MAIT\|Healthy_donor / disease group, cell group and cell class (v2)	TMIGD2 WIPF3 MCAM ADAM12	1.54e-04	182	66	4	ac7c83464487ecde3df6804a99551307bd768f21
ToppCell	COVID-19-kidney-Podocyte\|kidney / Disease (COVID-19 only), tissue and cell type	MAP6 TJP1 ZNF185 WIPF3	1.57e-04	183	66	4	fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAP6 TJP1 WIPF3 PHF21B	1.57e-04	183	66	4	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAP6 TJP1 WIPF3 PHF21B	1.57e-04	183	66	4	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	facs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP6 DZIP1 CLIP1 SH3BGRL2	1.57e-04	183	66	4	6e5b39c0170d62eb7fdd411dcfff51ed176573d0
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	MYOM1 CAMK2D AAK1 NLGN1	1.60e-04	184	66	4	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAP6 TJP1 WIPF3 PHF21B	1.60e-04	184	66	4	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAP6 TJP1 WIPF3 PHF21B	1.63e-04	185	66	4	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAP6 TJP1 WIPF3 PHF21B	1.63e-04	185	66	4	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	MYOM1 CAMK2D AAK1 NLGN1	1.63e-04	185	66	4	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBN1 CAMSAP2 CLIP1 STAT3	1.63e-04	185	66	4	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	COL6A3 GLI2 NLGN1 ADAM12	1.67e-04	186	66	4	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	LPS-antiTNF-Epithelial_alveolar\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CELSR1 FMN1 NLGN1 PRSS36	1.70e-04	187	66	4	201ff693e4756ee3e44762885b3a303a77eb535b
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARRB2 FMN1 SGK1 SYK	1.70e-04	187	66	4	39b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAP6 TJP1 WIPF3 SH3BGRL2	1.74e-04	188	66	4	9db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCell	MS-mono3\|MS / Condition, Cell_class and T cell subcluster	TJP1 SGK1 PCLO WIPF3	1.74e-04	188	66	4	a50a766c2f02e776c8e5c6e0833ec241c61831c4
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAP6 TJP1 WIPF3 SH3BGRL2	1.74e-04	188	66	4	047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCell	MS-mono3-\|MS / Condition, Cell_class and T cell subcluster	TJP1 SGK1 PCLO WIPF3	1.74e-04	188	66	4	e8c1c2941ca4919e0097a65b692b7af8018e8886
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	COL6A3 GLI2 DZIP1 PHF21B	1.77e-04	189	66	4	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	COVID-19-Heart-Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARRB2 GAS2L3 FMN1 SYK	1.77e-04	189	66	4	2586f4088721c5debec86c2b211b739fd33713eb
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	MYOM1 CAMK2D AAK1 NLGN1	1.81e-04	190	66	4	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	Severe-MAIT\|World / Disease group and Cell class	TMIGD2 NACA MCAM ADAM12	1.81e-04	190	66	4	7a92e0d6a021be23125495927b8571e25c83204a
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	COL6A3 GLI2 NLGN1 DZIP1	1.81e-04	190	66	4	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARRB2 FMN1 SYK PRSS36	1.81e-04	190	66	4	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 GLI2 CAMK2D ADAM12	1.81e-04	190	66	4	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 WIPF3 ADAM12 PKHD1L1	1.81e-04	190	66	4	a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 WIPF3 ADAM12 PKHD1L1	1.81e-04	190	66	4	0bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 WIPF3 ADAM12 PKHD1L1	1.81e-04	190	66	4	26e2237f65cb43723c5da853831b40df2982d6e4
ToppCell	Severe-MAIT\|Severe / Disease group and Cell class	TMIGD2 NACA MCAM ADAM12	1.81e-04	190	66	4	1c063dc1b62d9f9912aaf8d0297555a6545f5550
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	MYOM1 CAMK2D AAK1 NLGN1	1.85e-04	191	66	4	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL6A3 CAMK2D CLIP1 STAT3	1.85e-04	191	66	4	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	COL6A3 GLI2 NLGN1 ADAM12	1.85e-04	191	66	4	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	COVID-19-lung-Macrophage_PPARGhi_CD5Lhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARRB2 GAS2L3 FMN1 SYK	1.88e-04	192	66	4	bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP6 TJP1 WIPF3 SH3BGRL2	1.88e-04	192	66	4	ef0aba777072429a6ab7dcfcc305673975946580
ToppCell	moderate-Lymphoid-Treg\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMIGD2 AAK1 MCAM ADAM12	1.88e-04	192	66	4	e370ff5aaff7b7042ba9aaf93de43aa563b8b9f9
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	GAS2L3 FMN1 SGK1 SYK	1.88e-04	192	66	4	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SGK1 TMIGD2 ARID5A STAT3	1.88e-04	192	66	4	348d39da3016dc6dbfa65d108e5def35aa7f19dd
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP6 TJP1 WIPF3 SH3BGRL2	1.92e-04	193	66	4	3eaa0461618582a1754400624350d269d24e750a
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	ARRB2 GAS2L3 FMN1 SYK	1.92e-04	193	66	4	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	10x5'-blood\|World / Manually curated celltypes from each tissue	COL6A3 ARRB2 ZNF185 SH3BGRL2	1.92e-04	193	66	4	359d4242a7e5e51a3eaf6fe51bc1c653a402b054
ToppCell	CF-Epithelial\|CF / Disease state, Lineage and Cell class	TJP1 ZNF185 TEAD3 SH3BGRL2	1.92e-04	193	66	4	518901c2e36a79c6189cd0d9e6d36dbd4f56a79c
ToppCell	critical-Lymphoid-NK\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TJP1 FMN1 NLGN1 PYGO1	1.92e-04	193	66	4	6be11fef87af04ee7a3cc223882ccd4077caded9
ToppCell	CF-Epithelial-Epithelial_cell\|CF / Disease state, Lineage and Cell class	TJP1 ZNF185 TEAD3 SH3BGRL2	1.92e-04	193	66	4	4e3dda27c71b7fdac90d081f0d8e9ca3a8ea7820
ToppCell	COVID-19-Heart-Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	ARRB2 GAS2L3 FMN1 SYK	1.96e-04	194	66	4	f09675cd472200363c458952f00d2e41990800ee
ToppCell	severe-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CELSR1 CAMK2D APC PKHD1L1	1.96e-04	194	66	4	2fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL6A3 GLI2 NLGN1 ADAM12	1.96e-04	194	66	4	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARRB2 GAS2L3 FMN1 SYK	1.96e-04	194	66	4	663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GAS2L3 FMN1 SYK PRSS36	1.96e-04	194	66	4	45708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GAS2L3 FMN1 SGK1 SYK	2.00e-04	195	66	4	9d649ac7d2af313481069c95349efc0c68449e2b
ToppCell	Monocytes-NUPR1+_Monocytes\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ARRB2 GAS2L3 SYK PRSS36	2.00e-04	195	66	4	5e12201ce7ba912e7faa123ca200e609252ba288
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 GAS2L3 FMN1 SYK	2.00e-04	195	66	4	42bfdff88da1d07828c0ad65d412fb1752f0cee4
ToppCell	severe-B_cell\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CELSR1 CAMK2D APC PKHD1L1	2.00e-04	195	66	4	0fc3c605609c9e6bdea15d73c45def2188ae5fb1
ToppCell	Monocytes\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ARRB2 GAS2L3 SYK PRSS36	2.04e-04	196	66	4	ab0a8f5f388c9794d7f41f99fb0a5f2fd6fff6b3
ToppCell	Monocytes-IL1B+_Monocytes\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ARRB2 GAS2L3 SGK1 SYK	2.04e-04	196	66	4	7bc0735d324ac5a1661434cda4116ddd58296730
ToppCell	moderate-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMIGD2 AAK1 MCAM ADAM12	2.04e-04	196	66	4	9152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ARRB2 FMN1 CLTC SYK	2.08e-04	197	66	4	e2c53742c7d8d1b63d93843f82330b9e20f1faa6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 GAS2L3 FMN1 SYK	2.08e-04	197	66	4	d95565652ca318a2298d6918d54ba6367e9560f4
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-myeloid_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ARRB2 FMN1 CLTC SYK	2.08e-04	197	66	4	9838dbd1623babf8de7e9126a28fe5d3666bce42
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TJP1 ZNF185 TEAD3 SH3BGRL2	2.12e-04	198	66	4	fb3965049cb1961de0d2e74370868e46aa5050c8
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TJP1 ZNF185 TEAD3 SH3BGRL2	2.12e-04	198	66	4	72d91bd0c727ecadc41e023a16c9326158db1b7b
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GAS2L3 FMN1 SGK1 SYK	2.12e-04	198	66	4	0b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TJP1 ZNF185 TEAD3 SH3BGRL2	2.12e-04	198	66	4	441608034c787e55691558a480dcd07e37419138
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TJP1 ZNF185 TEAD3 SH3BGRL2	2.12e-04	198	66	4	9f5726aedd1fb132feab717a029fa302306461b5
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 MYOM1 GAS2L3 SYK	2.16e-04	199	66	4	5abfbccae147d399e4234f90ae5cd9529abe4dd1
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	MAP6 PCLO NACA APC	2.16e-04	199	66	4	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	Sigmoid-T_cell-Th17\|T_cell / Region, Cell class and subclass	TMIGD2 AAK1 MCAM ADAM12	2.16e-04	199	66	4	622f2ae4b1850b25f723a0385da49147dfec8285
ToppCell	mLN-(1)_T_cell-(14)_Tcm\|mLN / shred on region, Cell_type, and subtype	TMIGD2 NACA AAK1 STAT3	2.16e-04	199	66	4	3222454da504e119c78e666b90cc669ff0335b1a
ToppCell	mLN-T_cell-Tcm\|mLN / Region, Cell class and subclass	TMIGD2 NACA AAK1 STAT3	2.16e-04	199	66	4	b1237c8d1acad6737d8cb425dc4eb50724e2302c
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	MAP6 PCLO NACA APC	2.16e-04	199	66	4	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 FMN1 SGK1 SYK	2.20e-04	200	66	4	ea039de8bd8b325845ce361f84e600c6dad922ed
ToppCell	Biopsy_Other_PF\|World / Sample group, Lineage and Cell type	ARRB2 SGK1 NOP2 ARID5A	2.20e-04	200	66	4	fc41a9fb855ae5a5c73a769f18ec7a14f42f18ec
ToppCell	Tracheal-NucSeq-Immune_Myeloid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 GAS2L3 SGK1 SYK	2.20e-04	200	66	4	ad7ae5106141669b353800fece833b3cd5bdccee
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	FMN1 SYK INTS8 STAT3	2.20e-04	200	66	4	e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	MAPRE3 CAMK2D PCLO AAK1	2.20e-04	200	66	4	09fd3cb31bcc02444f1045f01fe39bce09359d35
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	GLI2 ZNF516 STOX1 INO80B	2.20e-04	200	66	4	b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Macrophage_other\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 FMN1 SGK1 SYK	2.20e-04	200	66	4	2d2835f97e0ff4f99d384f18e10876575f6bdefd
Computational	Neighborhood of MBD4	PAPOLA NACA INTS8	1.29e-04	25	43	3	GNF2_MBD4
Computational	Neighborhood of BNIP2	PAPOLA NACA INTS8	3.27e-04	34	43	3	GNF2_BNIP2
Computational	Muscle genes.	COL6A3 MYOM1 ADAM12	4.21e-04	37	43	3	MODULE_512
Computational	Genes in the cancer module 387.	COL6A3 MYOM1 ADAM12	9.66e-04	49	43	3	MODULE_387
Computational	Blood cells and cancer expression clusters.	COL6A3 PAPOLA FMN1 PHAX ARID5A INO80B STAT3	1.05e-03	407	43	7	MODULE_532
Computational	Genes in the cancer module 329.	COL6A3 MYOM1 ADAM12	1.09e-03	51	43	3	MODULE_329
Computational	Neighborhood of DENR	PAPOLA PPIH INTS8	1.09e-03	51	43	3	GNF2_DENR
Computational	Neighborhood of DAP3	PAPOLA NACA PPIH INTS8	1.26e-03	119	43	4	GNF2_DAP3
Computational	Genes in the cancer module 459.	COL6A3 PAPOLA FMN1 PHAX ARID5A INO80B STAT3	1.46e-03	431	43	7	MODULE_459
Computational	Genes in the cancer module 378.	COL6A3 PAPOLA FMN1 PHAX ARID5A INO80B STAT3	1.54e-03	435	43	7	MODULE_378
Computational	Genes in the cancer module 317.	COL6A3 PAPOLA FMN1 PHAX ARID5A INO80B STAT3	1.65e-03	440	43	7	MODULE_317
Computational	Genes in the cancer module 256.	PAPOLA NUP214 CHAMP1	1.83e-03	61	43	3	MODULE_256
Computational	Genes in the cancer module 255.	COL6A3 PAPOLA FMN1 PHAX ARID5A INO80B STAT3	1.87e-03	450	43	7	MODULE_255
Computational	Blood cells and cancer expression cancer.	COL6A3 PAPOLA FMN1 PHAX ARID5A INO80B STAT3	2.34e-03	468	43	7	MODULE_179
Computational	Genes in the cancer module 37.	COL6A3 PAPOLA FMN1 PHAX ARID5A INO80B STAT3	2.43e-03	471	43	7	MODULE_37
Computational	Neighborhood of RBBP6	PAPOLA NACA INTS8	2.71e-03	70	43	3	GNF2_RBBP6
Computational	Genes in the cancer module 136.	COL6A3 PAPOLA FMN1 PHAX ARID5A INO80B STAT3	3.07e-03	491	43	7	MODULE_136
Disease	osteoarthritis, spine, body mass index	NLGN1 CLIP1	1.21e-04	8	62	2	EFO_0004340, EFO_1000787
Disease	frailty measurement	NLGN1 INO80	1.07e-03	23	62	2	EFO_0009885
Disease	S-warfarin measurement	FMN1 NLGN1 ADAM12	1.13e-03	97	62	3	EFO_0803323
Disease	colorectal cancer (implicated_via_orthology)	APC STAT3	1.82e-03	30	62	2	DOID:9256 (implicated_via_orthology)
Disease	heart conduction disease (implicated_via_orthology)	CAMK2D PYGO1	2.07e-03	32	62	2	DOID:10273 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
APQQALPQSFPKPGT	USP26	751	Q9BXU7
PCSPQAFPPAKKQPF	ERI2	536	A8K979
PASPKPAGKQNGIQN	ARID5A	21	Q03989
PQNEISPSKPFGPQE	CXorf66	221	Q5JRM2
PKVQTTPPPAVQGQK	AAK1	601	Q2M2I8
PNLAAKNVFPPPSQT	ADAM12	186	O43184
PQTKFGQPAAVPCPK	CELSR1	2066	Q9NYQ6
KVQFAPEKPGPQPSA	ARRB2	171	P32121
NVPTGPNNKPKLPVV	PPIH	156	O43447
KPSPPAPAALGKVFN	FMN1	491	Q68DA7
QSSFPVKQAKPGPPQ	INTS8	156	Q75QN2
SPLSKGNNVPGNPKN	INO80	1516	Q9ULG1
SIPQFPVPPKSQKAQ	NPAT	981	Q14207
KHPLKPDNQPFPQSV	HRG	486	P04196
VKDQGPSVPVPPKNQ	MAP6	526	Q96JE9
TPNPNSLKFIPGKPV	NFU1	66	Q9UMS0
PFNRPQGVQPKTGPF	SYK	106	P43405
PQNQRESKPGIFPAK	FSIP2	5771	Q5CZC0
SPQPQQTSPKKDAAP	PCLO	676	Q9Y6V0
PPAAKPGSPQAKSLQ	NUP214	671	P35658
ALASQVKPPPFPQGN	GLI2	1156	P10070
PTAKQDDPKQQPSPF	NLGN1	691	Q8N2Q7
DAGPTQPSPAKPQLK	INO80B	56	Q9C086
VNPQSFPAPKENPDK	PAPOLA	416	P51003
GPAFPTQPQKTQSDP	PRSS36	296	Q5K4E3
KNPPKFAPLPENSVN	CEFIP	171	Q711Q0
QNSGPKESNVPPPSA	GFY	336	I3L273
KPQKQSHFPETLGPP	CHAMP1	226	Q96JM3
QSQPSDGAPQAKPVP	GAS2L3	536	Q86XJ1
NQPSVKPAAAKPAPA	COL6A3	2901	P12111
IQPSPSLQPSFNPGK	GON4L	1006	Q3T8J9
SPQPQCPSAQGSKPK	C16orf90	41	A8MZG2
APPPNPGDQIFNKSK	MAPRE3	136	Q9UPY8
NISPFPQPPQKDEGS	FOXR2	106	Q6PJQ5
PNQNPFLKPTGRAPQ	GLIPR1L1	211	Q6UWM5
ESPQKKPPFQPRSVQ	C3orf86	41	P0DN24
SPPQPSPQKQIRDFK	CAMSAP2	931	Q08AD1
NIPQKPSQPAAKEPS	CLIP1	166	P30622
PIKPPCIPNGKENFS	CAMK2D	476	Q13557
PPKPEPFQFGQSSQK	PHAX	91	Q9H814
GNPPPHFSISKQNPS	MCAM	276	P43121
PNTFGQAKAPPPKQD	PYGO1	226	Q9Y3Y4
KKITPPFNPNVSGPN	SGK1	366	O00141
GVAAPPPKNSFNNPA	INPPL1	971	O15357
EGVPSAPQNPPQRKK	SETD5	1051	Q9C0A6
LPPKSPSFQAPPQKA	WIPF3	326	A6NGB9
FNIQPNKKSPPEPRV	CYB5R1	161	Q9UHQ9
QKQNDTPKGPQPPTV	NOP2	771	P46087
QPKFGAPDGPQQKTS	NPAP1	771	Q9NZP6
LPVPPPQNKGSFGKN	DZIP1	701	Q86YF9
GQPKPILQKQSTFPQ	APC	1921	P25054
PPTGNQPFPKKAVDV	CLTC	236	Q00610
AKFSAQPQGPPPAKG	ZNF516	976	Q92618
SPTQQPRPKGFPKVG	TMIGD2	266	Q96BF3
PPKQPPTFQKATVVS	PHF21B	91	Q96EK2
EKKPTQGNPLPPQIF	SH3BGRL2	56	Q9UJC5
PSQTGPKEKPFQKPR	STOX1	521	Q6ZVD7
NPKNVNFFTKPPIGT	STAT3	486	P40763
QNKFSPPSPLPQAVF	TEAD3	141	Q99594
QPGPSQDIKPFAQPA	TEAD3	171	Q99594
AAQPGQPFPQQPSVK	PKHD1L1	4091	Q86WI1
SKPDPPPSQNKPATF	TJP1	1471	Q07157
NFTPPSPFANKLQGP	UBN1	816	Q9NPG3
VPGQQPQAAKSPSPV	ZFP91	91	Q96JP5
PQQQFPKANGTPKSA	ZNF185	101	O15231
QVPNPESPGKSFQPI	YEATS2	441	Q9ULM3
PVPTPSAKQPVTKNN	NACA	1871	E9PAV3
ELTPPPQKAAPQGKS	MYOM1	906	P52179
GQKPQTPSASLQPPF	NEXN-AS1	146	Q8NBZ9