Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessreproductive senescence

SYCP2L JMJD1C

1.72e-052862GO:1990636
GeneOntologyBiologicalProcessmicrotubule-based process

ADCY10 DST SYNE2 APC2 VPS13A APC CEP295 INO80 MAP10 STAG2 DNAH14 KPNB1 DNAH1 FOXJ1 ANKRD53

2.88e-0510588615GO:0007017
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

DST SYNE2 APC2 APC CEP295 INO80 MAP10 STAG2 KPNB1 DNAH1 FOXJ1 ANKRD53

4.29e-057208612GO:0000226
DomainAPC_dom

APC2 APC

2.05e-052852IPR026831
DomainAPC_N

APC2 APC

2.05e-052852IPR032038
DomainAPC_basic_dom

APC2 APC

2.05e-052852IPR009234
DomainApc_fam

APC2 APC

2.05e-052852IPR026818
DomainAPC_r

APC2 APC

2.05e-052852PF05923
DomainSAMP

APC2 APC

2.05e-052852PF05924
DomainAPC_rpt

APC2 APC

2.05e-052852IPR009223
DomainSAMP

APC2 APC

2.05e-052852IPR009224
DomainAPC_basic

APC2 APC

2.05e-052852PF05956
DomainAPC_N_CC

APC2 APC

2.05e-052852PF16689
DomainVPS13

VPS13C VPS13A

6.12e-053852IPR026847
DomainTFSII

TCEA1 TCEA2

6.12e-053852IPR006289
DomainVPS13_mid_rpt

VPS13C VPS13A

6.12e-053852PF16910
DomainVPS13

VPS13C VPS13A

6.12e-053852PF16908
DomainVPS13_N2

VPS13C VPS13A

6.12e-053852IPR031646
DomainVPS13_mid_rpt

VPS13C VPS13A

6.12e-053852IPR031642
DomainPP2A_PR55

PPP2R2A PPP2R2C

1.22e-044852IPR000009
DomainPP2A_PR55_CS

PPP2R2A PPP2R2C

1.22e-044852IPR018067
DomainVPS13_C

VPS13C VPS13A

1.22e-044852PF16909
DomainSHR-BD

VPS13C VPS13A

1.22e-044852IPR009543
DomainVPS13_C

VPS13C VPS13A

1.22e-044852IPR031645
DomainTF_IIS-rel

TCEA1 TCEA2

1.22e-044852IPR016492
DomainSHR-BD

VPS13C VPS13A

1.22e-044852PF06650
DomainPR55_2

PPP2R2A PPP2R2C

1.22e-044852PS01025
DomainPR55_1

PPP2R2A PPP2R2C

1.22e-044852PS01024
DomainATG_C

VPS13C VPS13A

2.03e-045852PF09333
DomainAutophagy-rel_C

VPS13C VPS13A

2.03e-045852IPR015412
DomainZnf_TFIIS

TCEA1 TCEA2

3.03e-046852IPR001222
DomainZnF_C2C2

TCEA1 TCEA2

3.03e-046852SM00440
DomainZF_TFIIS_1

TCEA1 TCEA2

3.03e-046852PS00466
DomainZF_TFIIS_2

TCEA1 TCEA2

3.03e-046852PS51133
DomainTFIIS_C

TCEA1 TCEA2

3.03e-046852PF01096
DomainArm

APC2 APC KPNB1

3.73e-0431853PF00514
DomainTFS2M

TCEA1 TCEA2

4.24e-047852SM00510
DomainTFIIS_M

TCEA1 TCEA2

4.24e-047852PF07500
DomainVPS13_N

VPS13C VPS13A

5.63e-048852IPR026854
DomainTFIIS_cen_dom

TCEA1 TCEA2

5.63e-048852IPR003618
Domain-

TCEA1 TCEA2

5.63e-0488521.10.472.30
DomainChorein_N

VPS13C VPS13A

5.63e-048852PF12624
DomainTFIIS_CENTRAL

TCEA1 TCEA2

5.63e-048852PS51321
DomainARM

APC2 APC KPNB1

7.96e-0440853SM00185
DomainTFIIS/CRSP70_N_sub

TCEA1 TCEA2

9.00e-0410852IPR003617
DomainTFS2N

TCEA1 TCEA2

9.00e-0410852SM00509
DomainArmadillo

APC2 APC KPNB1

1.28e-0347853IPR000225
Domain-

TCEA1 TCEA2

1.55e-03138521.20.930.10
DomainTFIIS_N

TCEA1 TCEA2

1.55e-0313852PS51319
DomainMed26

TCEA1 TCEA2

1.55e-0313852PF08711
DomainTFIIS_N

TCEA1 TCEA2

1.80e-0314852IPR017923
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH1

1.80e-0314852IPR024317
DomainDynein_HC_stalk

DNAH14 DNAH1

1.80e-0314852IPR024743
DomainMT

DNAH14 DNAH1

1.80e-0314852PF12777
DomainAAA_8

DNAH14 DNAH1

1.80e-0314852PF12780
DomainDHC_fam

DNAH14 DNAH1

2.07e-0315852IPR026983
DomainDynein_heavy_dom

DNAH14 DNAH1

2.07e-0315852IPR004273
DomainDynein_heavy

DNAH14 DNAH1

2.07e-0315852PF03028
DomainLeu-rich_rpt_Cys-con_subtyp

KDM2A FBXL5

3.33e-0319852IPR006553
DomainLRR_CC

KDM2A FBXL5

3.33e-0319852SM00367
DomainARM-type_fold

APC2 APC HUWE1 STAG2 PDCD4 KPNB1

4.50e-03339856IPR016024
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PPP2R2A HOXB6 PPP2R2C VPS13C RALGPS1 EEPD1 MACROD1 KDM2A RABGAP1 NUDCD3 HUWE1 JMJD1C STAG2 DNAH14 ADGRG6 DNAH1

1.08e-061489891628611215
Pubmed

Deployment of the human immunodeficiency virus type 1 protein arsenal: combating the host to enhance viral transcription and providing targets for therapeutic development.

PPP2R2A PPP2R2C CD4 KPNB1

2.22e-063689422422068
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SET HIVEP1 DST SYNE2 UGDH KDM2A JMJD1C STAG2 KPNB1

5.34e-0649789923414517
Pubmed

Interaction of Pdcd4 with eIF4E inhibits the metastatic potential of hepatocellular carcinoma.

EIF4E PDCD4

6.48e-06289220359850
Pubmed

Fascin Regulates Nuclear Movement and Deformation in Migrating Cells.

SYNE2 FSCN1

6.48e-06289227554857
Pubmed

Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium.

APC2 APC

6.48e-06289227694902
Pubmed

Epithelial-derived IL-33 promotes intestinal tumorigenesis in Apc Min/+ mice.

APC IL33

6.48e-06289228710436
Pubmed

Brain-specific transcript variants of 5' and 3' ends of mouse VPS13A and VPS13C.

VPS13C VPS13A

6.48e-06289217196930
Pubmed

INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis.

APC INO80

6.48e-06289229383140
Pubmed

APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression.

APC2 APC

6.48e-06289231291912
Pubmed

IL-33 activates tumor stroma to promote intestinal polyposis.

APC IL33

6.48e-06289225918379
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

HIVEP1 SYNE2 APC KDM2A ZNF518B MYO15A FSCN1 JMJD1C

8.63e-0639889835016035
Pubmed

Interferon Regulatory Factor 6 Is Necessary for Salivary Glands and Pancreas Development.

KRT7 HOXB6 TP63

1.07e-051789328898113
Pubmed

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.

VPS13C VPS13A

1.94e-05389230093493
Pubmed

E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling.

APC HUWE1

1.94e-05389228137882
Pubmed

mTOR inhibition suppresses Myc-driven polyposis by inducing immunogenic cell death.

EIF4E APC

1.94e-05389237138032
Pubmed

Isolation and characterization of a cDNA encoding a new type of human transcription elongation factor S-II.

TCEA1 TCEA2

1.94e-0538928566795
Pubmed

TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes.

VPS13C VPS13A

1.94e-05389233087848
Pubmed

Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits.

PPP2R2A PPP2R2C

1.94e-0538929514514
Pubmed

Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.

APC2 APC

1.94e-05389223840886
Pubmed

Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models.

ADCY10 KCNU1

3.87e-05489227627854
Pubmed

Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.

FRY TP63

3.87e-05489224880342
Pubmed

Analysis of the human VPS13 gene family.

VPS13C VPS13A

3.87e-05489215498460
Pubmed

Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.

APC HUWE1

3.87e-05489227184401
Pubmed

Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells.

PPP2R2A KPNB1

3.87e-05489220711181
Pubmed

Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral.

RALGPS1 RALGPS2

3.87e-05489210747847
Pubmed

A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destruction.

APC2 APC

3.87e-05489226393419
Pubmed

Identification of a novel tissue-specific transcriptional activator FESTA as a protein that interacts with the transcription elongation factor S-II.

TCEA1 TCEA2

6.44e-05589212761297
Pubmed

Activation of protein phosphatase-2A1 by HIV-1 Vpr cell death causing peptide in intact CD(4+) T cells and in vitro.

PPP2R2A PPP2R2C

6.44e-05589215578586
Pubmed

The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer.

APC IL33

6.44e-05589231165767
Pubmed

Transcription elongation factor Tcea3 regulates the pluripotent differentiation potential of mouse embryonic stem cells via the Lefty1-Nodal-Smad2 pathway.

TCEA1 TCEA2

6.44e-05589223169579
Pubmed

Analysis of clinical characteristics and differential diagnosis of the lung biopsy specimens in 99 adenocarcinoma cases and 111 squamous cell carcinoma cases: utility of an immunohistochemical panel containing CK5/6, CK34βE12, p63, CK7 and TTF-1.

KRT7 TP63

6.44e-05589225063315
Pubmed

Heterogeneity and tissue-specific expression of eukaryotic transcription factor S-II-related protein mRNA.

TCEA1 TCEA2

6.44e-0558921917889
Pubmed

Usefulness of immunocytochemistry using a Breast Marker antibody cocktail targeting P63/cytokeratin7/18/cytokeratin5/14 for fine needle aspiration of the breast: a retrospective cohort study of 139 cases.

KRT7 TP63

6.44e-05589227060708
Pubmed

Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome.

CD4 DST KCNB1

6.91e-05318938034307
Pubmed

Scanning the human proteome for calmodulin-binding proteins.

SET DST SYNE2 HUWE1

9.43e-059289415840729
Pubmed

An EB1-binding motif acts as a microtubule tip localization signal.

DST APC

9.65e-05689219632184
Pubmed

MYC-nick promotes cell migration by inducing fascin expression and Cdc42 activation.

APC FSCN1

9.65e-05689227566402
Pubmed

Identification of EloA-BP1, a novel Elongin A binding protein with an exonuclease homology domain.

TCEA1 TCEA2

9.65e-05689212943681
Pubmed

HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.

APC HUWE1

9.65e-05689228003334
Pubmed

Role of p70S6K1-mediated phosphorylation of eIF4B and PDCD4 proteins in the regulation of protein synthesis.

EIF4E PDCD4

9.65e-05689223105104
Pubmed

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

APC2 APC

9.65e-05689210074433
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TCEA1 SET UGGT1 RALGPS2 APC CEP295 INO80 HUWE1 MTO1 STAG2 IKBIP

1.02e-041084891111544199
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

HIVEP1 DST APC KIAA1958 RABGAP1 HUWE1 JMJD1C

1.02e-0441889734709266
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

DST JAGN1 VPS13C SYNE2 VPS13A RABGAP1 IKBIP KPNB1

1.07e-0456889837774976
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TMTC3 SEM1 VPS13C UGGT1 APC CEP295 NUDCD3 HUWE1 JMJD1C

1.11e-0473389934672954
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FRY DST VPS13C EIF4E VPS13A PCARE CEP295 HUWE1 DNAH14

1.14e-0473689929676528
Pubmed

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization.

APC2 APC

1.35e-04789210330403
Pubmed

HSF1 transcriptional activity is modulated by IER5 and PP2A/B55.

PPP2R2A PPP2R2C

1.35e-04789225816751
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

USP36 DST EFCAB6 VPS13C WRN UGDH VPS13A APC HUWE1

1.71e-0477789935844135
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

FRY TRAF3 DST KCNB1 SYNE2 APC2 APC HUWE1 FSCN1 KPNB1

1.78e-04963891028671696
Pubmed

Cell type-specific expression of adenomatous polyposis coli in lung development, injury, and repair.

TP63 APC

1.79e-04889220658693
Pubmed

miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression.

STAG2 PDCD4

1.79e-04889230552326
Pubmed

The role of Vpr in HIV-1 pathogenesis.

PPP2R2A PPP2R2C

1.79e-04889215638722
Pubmed

Type 2A protein phosphatase, the complex regulator of numerous signaling pathways.

PPP2R2A PPP2R2C

1.79e-04889211007961
Pubmed

CFAP43 modulates ciliary beating in mouse and Xenopus.

DNAH1 FOXJ1

1.79e-04889231884020
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

TCEA1 SET KIAA1958 HUWE1 FSCN1 IKBIP KPNB1

2.06e-0446989727634302
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

DST KDM2A ZNF518B URB2 HUWE1 KPNB1

2.16e-0433289637433992
Pubmed

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta.

APC2 APC

2.30e-0498929601641
Pubmed

Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development.

PPP2R2A PPP2R2C

2.30e-04989219762425
Pubmed

Regulatory effects of programmed cell death 4 (PDCD4) protein in interferon (IFN)-stimulated gene expression and generation of type I IFN responses.

EIF4E PDCD4

2.30e-04989222586265
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

HIVEP1 TMTC3 JAGN1 SYNE2 VPS13A CEP295 URB2 STAG2

2.35e-0463889831182584
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DST UGGT1 SYNE2 URB2 HUWE1 FSCN1 STAG2 KPNB1

2.75e-0465389822586326
Pubmed

Two dominant host resistance genes to pre-B lymphoma in wild-derived inbred mouse strain MSM/Ms.

APC CFB

2.88e-04108928706013
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

EVI5 PPP2R2A HOXB6 SET TRAF3 DST UGGT1 SYNE2 HUWE1 STAG2 PDCD4 KPNB1

3.02e-041440891230833792
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

TCEA1 KRT7 PPP2R2A SET UGGT1 EIF4E UGDH RABGAP1 NUDCD3 HUWE1 PDCD4 KPNB1

3.32e-041455891222863883
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

KRT7 DST APC KDM2A FSCN1 MLYCD

3.33e-0436089633111431
Pubmed

cDNA cloning and expression analysis of new members of the mammalian F-box protein family.

KDM2A FBXL5

3.51e-041189210945468
Pubmed

Meis1 is required for the maintenance of postnatal thymic epithelial cells.

CD4 TP63

3.51e-041189224594519
Pubmed

E2f4 is required for normal development of the airway epithelium.

TP63 FOXJ1

3.51e-041189217383628
Pubmed

SOX21 modulates SOX2-initiated differentiation of epithelial cells in the extrapulmonary airways.

TP63 FOXJ1

3.51e-041189234286693
Pubmed

Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11.

HUWE1 KPNB1

3.51e-041189211809816
Pubmed

Antigen expression of human eccrine sweat glands.

KRT7 TP63

3.51e-041189219032382
Pubmed

Expression QTL and regulatory network analysis of microtubule-associated protein tau gene.

SET DST

3.51e-041189219233709
Pubmed

Reactivation of the Hedgehog pathway in esophageal progenitors turns on an embryonic-like program to initiate columnar metaplasia.

KRT7 TP63

3.51e-041189233882290
Pubmed

Identification of potential bladder progenitor cells in the trigone.

KRT7 TP63

4.20e-041289224992712
Pubmed

Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus.

KRT7 TP63

4.20e-041289229019984
Pubmed

p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes.

TP63 SYNE2

4.20e-041289228595999
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP36 PPP2R2A DST VPS13C RALGPS1 INO80 NUDCD3

4.26e-0452989714621295
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

TCEA1 APC KDM2A PDCD4 KPNB1

4.68e-0425089533536335
Pubmed

ΔNp63 regulates Sfrp1 expression to direct salivary gland branching morphogenesis.

KRT7 TP63

4.96e-041389238722977
Pubmed

Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29.

PPP2R2A PPP2R2C

4.96e-041389218971272
Pubmed

Residual embryonic cells as precursors of a Barrett's-like metaplasia.

KRT7 TP63

4.96e-041389221703447
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

USP36 TCEA1 PPP2R2A EIF4E UGDH APC KDM2A INO80

5.44e-0472489836232890
Pubmed

Increasing the ratio of PP2A core enzyme to holoenzyme inhibits Tat-stimulated HIV-1 transcription and virus production.

PPP2R2A PPP2R2C

5.78e-04148929400615
Pubmed

Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.

PPP2R2A PPP2R2C

5.78e-041489216048649
Pubmed

Autophagy acts through TRAF3 and RELB to regulate gene expression via antagonism of SMAD proteins.

TRAF3 RABGAP1

5.78e-041489229146913
Pubmed

Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr.

PPP2R2A PPP2R2C

5.78e-04148929013886
Pubmed

Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors.

TP63 FOXJ1

5.78e-041489225564622
Pubmed

A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.

TCEA1 WRN APC

6.31e-046589327453043
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

VPS13C MAP10 JMJD1C DNAH1

6.58e-0415389410718198
Pubmed

β-Catenin-SOX2 signaling regulates the fate of developing airway epithelium.

TP63 FOXJ1

6.65e-041589222421361
Pubmed

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.

APC2 APC

6.65e-041589216510875
Pubmed

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2.

FSCN1 KPNB1

6.65e-041589220603015
Pubmed

Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential.

TP63 FOXJ1

6.65e-041589225358791
Pubmed

Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration.

PPP2R2A PPP2R2C

6.65e-041589216041367
Pubmed

Prmt5 promotes ciliated cell specification of airway epithelial progenitors via transcriptional inhibition of Tp63.

TP63 FOXJ1

6.65e-041589237364687
Pubmed

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.

HIVEP1 KDM2A HUWE1

7.51e-046989332238831
Pubmed

Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice.

KRT7 TP63

7.59e-041689233495473
Pubmed

Functional proteomics mapping of a human signaling pathway.

KRT7 HIVEP1 DST ZFYVE9 KDM2A HUWE1 KPNB1

8.18e-0459189715231748
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

APC2 APC KPNB1

3.35e-0443573409
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2A PPP2R2C

9.99e-0415572696
GeneFamilyDyneins, axonemal

DNAH14 DNAH1

1.29e-0317572536
GeneFamilyF-box and leucine rich repeat proteins

KDM2A FBXL5

1.97e-0321572558
GeneFamilyPHD finger proteins|Lysine demethylases

KDM2A JMJD1C

2.58e-0324572485
CoexpressionGABRIELY_MIR21_TARGETS

UGGT1 SYNE2 VPS13A RALGPS2 FAM217B APC RABGAP1 PDCD4 FBXL5

6.25e-07289899M2196
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

EVI5 PPP2R2A HIVEP1 DST ZFYVE9 EIF4E WRN VPS13A RABGAP1 ADGRG6

4.16e-064668910M13522
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

EVI5 PPP2R2A HIVEP1 DST ZFYVE9 SYNE2 EIF4E WRN VPS13A APC RABGAP1 STAG2 ADGRG6

6.24e-068568913M4500
CoexpressionGSE7509_FCGRIIB_VS_TNFA_IL1B_IL6_PGE_STIM_DC_DN

TCEA2 HOXB6 SET DST SYNE2 MYO15A

1.45e-05154896M6824
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000

TRAF3 WRN VPS13A APC RABGAP1 ZNF518B INO80 FSCN1 KPNB1

1.69e-05369859DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000

TCEA1 SYCP2L KRT7 SET EFCAB6 RHPN2 TP63 SYNE2 RALGPS2 APC KIAA1958 PLPPR3 CEP295 IL33

3.57e-059898514Facebase_RNAseq_e10.5_Maxillary Arch_1000
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ST6GALNAC1 USP36 LRRN3 CD4 DST SYNE2 ANKRD36C

1.22e-0719588722191d361af136942508f1553ff41a626ed982ad
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5A PPP2R2C ADGRF1 LRRD1 ADGRG6 FOXJ1

1.61e-061818867af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST KCNB1 VPS13C UGGT1 VPS13A HUWE1

2.48e-061958863e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST KCNB1 VPS13C UGGT1 VPS13A HUWE1

2.48e-061958867796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

TCEA1 DST TMTC3 VPS13C SYNE2 STAG2

2.78e-06199886c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FRY DST SYNE2 FSCN1 IL33 ADGRG6

2.86e-062008867eb366b2c5394af7c77650bde6261e7dac67154e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT7 UGDH RALGPS2 ANKRD36C ADGRF1 FOXJ1

2.86e-062008861c02a7f4047d1d2208cc522c6bb4a4989d7845bb
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT7 UGDH RALGPS2 ANKRD36C ADGRF1 FOXJ1

2.86e-0620088603051d2190244208905e1611019d4b8fd200bae0
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature_-_proliferative|E16.5-samps / Age Group, Lineage, Cell class and subclass

ADCY10 EVI5 HOXB6 ADGRF1 LRRD1

7.51e-0613688596370f0e3abf1c9ec7a91595b5d0f97ac2ab4b78
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT7 ANKRD36C ADGRF1 LRRD1 CFB

1.60e-0515988560b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB6 CD4 DST ZFYVE9 MYO15A

1.65e-051608850544bc465af208da448858d6e174ff56f2e08a46
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DST SYNE2 RABGAP1 APOC4 ADGRG6

1.97e-051668857a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DST SYNE2 RABGAP1 APOC4 ADGRG6

1.97e-05166885bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCellClub_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

ST6GALNAC1 KRT7 SYNE2 ADGRF1 CFB

2.61e-0517688588c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

SYNE2 VPS13A HUWE1 ANKRD36C JMJD1C

2.98e-05181885f2315414e714ac86211546a935660c4be6e85f1b
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HIVEP1 CD4 CLCN4 MLYCD FOXJ1

3.14e-05183885807d64deaf4e50dccf6f831f88578a6d903c1421
ToppCellNS-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ST6GALNAC1 KRT7 TP63 FSCN1 IL33

3.40e-05186885c28f62524637c7eb9c43c9ec38fb12dfec6f5566
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

VPS13C SYNE2 HUWE1 ANKRD36C JMJD1C

3.57e-05188885ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellIPF-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

USP36 DST TP63 IL33 IKBIP

3.76e-051908854f15842b424eefadbfe451875e517cf70e29607f
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEA1 SET VPS13C SYNE2 STAG2

3.85e-0519188560c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ST6GALNAC1 FRY CD4 EEPD1 SYNE2

3.85e-051918859c747f8cc1cdce45e839b661d782e1e8cfb79578
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEA1 SET VPS13C SYNE2 STAG2

3.85e-0519188509db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEA1 SET VPS13C SYNE2 STAG2

3.85e-05191885973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C UGDH JMJD1C IL33 IKBIP

3.95e-0519288511088878043a6ff95ba1970361256a82e434b80a
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

USP36 SYNE2 KDM2A ANKRD36C JMJD1C

3.95e-0519288547646d7e4990be85072987f92bf18d52f8da752e
ToppCellcellseq-Epithelial-Epithelial_Glandular-Goblet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.05e-0519388571bf8fb5314b79cb30f4eb9c8459b21f10cd6d35
ToppCellcellseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.05e-05193885b05e110b13d35d34294357c8e1c4fd23bf4b6c92
ToppCelldroplet-Bladder-nan-24m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT7 TP63 EEPD1 FSCN1 IL33

4.05e-051938859d7bc71c4ae871aad057d3beb6e06c929ae17203
ToppCellClub_cells|World / lung cells shred on cell class, cell subclass, sample id

ST6GALNAC1 KRT7 SYNE2 ANKRD36C ADGRF1

4.05e-051938859d3165dc5763a07a7d873f497624d9d6528fa2db
ToppCellBL-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KRT7 DST TP63 FSCN1 IL33

4.15e-051948852932f704656ca368565ec12f3452af3b18e8df12
ToppCellcellseq-Epithelial-Epithelial_Glandular|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.15e-05194885d0fb1ff5cf0738881e114a58f0b27489f781d72b
ToppCellSecretory|World / shred by cell class for bronchial biopsy

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.25e-0519588552f8281fe0df67cec3faa780a23ed6343ed5a6ba
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.36e-05196885c18874f37b90e6afacc562b2082b67ea8a7cb4a4
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.36e-051968852c3fbfbb08cd327cd97b3fa5a6f83b6d50771fb7
ToppCelltumor_Lung-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

LRRN3 CD4 SEM1 TP63 IRAG2

4.36e-051968855a0b5aeff7e535781ea2a4c85799bb468afcb6f8
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.36e-05196885a52879a4c822c5e4be569f01f845a795e00c5f4b
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ST6GALNAC1 DST TP63 SYNE2 IL33

4.36e-051968853b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RHPN2 RALGPS1 RALGPS2 KIAA1958 DNAH14

4.36e-051968856ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell15-Trachea|15 / Age, Tissue, Lineage and Cell class

ST6GALNAC1 KRT7 IRAG2 ADGRF1 FOXJ1

4.36e-05196885fd17403422cf95c24f6be1c2d78764bb352f7f2e
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.36e-051968857a4d502550e9e37dc42f2ff1be3c896afe365d7f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.36e-0519688560ea673ed887fe3890c5cf4ff4165384b76d7361
ToppCell367C-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DST TP63 IRAG2 IL33 IKBIP

4.36e-05196885e8db58e82300981f981402618a1befb91f6690fd
ToppCell367C-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DST TP63 IRAG2 IL33 IKBIP

4.36e-051968852cf42b702ea15adfa6bbd86a3c9613271863f86c
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ST6GALNAC1 EEPD1 SYNE2 NKX2-3 PDCD4

4.46e-0519788566339b5aae3952f5c484c9dcb0cfb4fbd828d4cb
ToppCellBasal_cells|World / lung cells shred on cell class, cell subclass, sample id

ST6GALNAC1 DST TP63 SYNE2 IL33

4.46e-0519788524360b660000bdfb999d58fbf4e29585a97e1785
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWA3A EFCAB6 KCNB1 SYNE2 PLPPR3

4.46e-0519788574a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell3'-Broncho-tracheal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 DST TP63 SYNE2 IL33

4.46e-051978855d33f8a6940431093e927b186fb9b630a89d8ec1
ToppCellproximal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.57e-051988853477202c4f702d8f75231b13d4b5216f56d981d7
ToppCellproximal-Epithelial-Goblet|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.57e-05198885e7e1c430486a81280abc4a7e7f5bc3713dd20737
ToppCellBronchial_Biopsy|World / Tissue, Lineage and Cell class of Lung Cells from 10X

DST TP63 SYNE2 IRAG2 IL33

4.57e-05198885f5b7013045b61fc56894f80092f799770dde1c8f
ToppCellproximal-Epithelial-Goblet-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.57e-05198885da7b40eb00bb5e454e1cfcd1219dc0d84712592a
ToppCellmedial-2-Epithelial-Mucous|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.68e-051998854737250b7ffa7cc19eb6b057d35d78f13b1afe66
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.68e-051998858bf8d7cd774479f065bbbbcb5a4bd1aa91aa0d85
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.

DST APC RABGAP1 ANKRD36C IL33

4.68e-05199885b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCellmedial-Epithelial-Mucous|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.68e-051998854385963ab25b5378e7964b984028c25b27e5794e
ToppCelldistal-2-Epithelial-Mucous|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.68e-05199885c0275b5011c2bb08e873955afe2e213ec8070d0e
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.68e-051998850c060ef64341659f4b1247d0264ac12e53a7e12e
ToppCelldistal-Epithelial-Mucous-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.68e-051998850af89ef40807fc4ad79ab82a2186ab6e866c6931
ToppCellmedial-Epithelial-Mucous-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.68e-0519988553198bcf5f2f012a3ed1600d95c0923d6976a099
ToppCelldistal-Epithelial-Mucous|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.68e-05199885a7fe7b792d696f369ad0310a772160a1729ef223
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT7 UGDH RALGPS2 ANKRD36C ADGRF1

4.79e-05200885f386a86b127433cbac306950443355bd723080ff
ToppCellNS-moderate-d_07-13-Epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.79e-0520088585940b4bf7971b872469dea8b8d7a45bdeb2a909
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ST6GALNAC1 EFCAB6 ADGRF1 DNAH1 FOXJ1

4.79e-0520088596701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DST TMTC3 TP63 SYNE2 ADGRF1

4.79e-0520088597f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellNasal_Brush-Epithelial|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ST6GALNAC1 KRT7 SYNE2 ANKRD36C ADGRF1

4.79e-052008857911073119ee47a37b68b73fc54f063e902a5067
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

DST ZNF518B FSCN1 JMJD1C IL33

4.79e-052008853b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCellBiopsy_IPF-Epithelial-Basal|Biopsy_IPF / Sample group, Lineage and Cell type

KRT7 DST CDHR1 TP63 IL33

4.79e-052008855cea84581201cee7ba8141b96e65864f4fd67113
ToppCellBronchus_Control_(B.)-Epithelial-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ST6GALNAC1 KRT7 SYNE2 ANKRD36C ADGRF1

4.79e-05200885f5bc7d30aa03dd0f95eb64255bd1a2543be8d327
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT7 UGDH RALGPS2 ANKRD36C ADGRF1

4.79e-05200885b75154417c215b8853186bff46d624ebd387ac4f
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 KRT7 ANKRD36C ADGRF1 CFB

4.79e-05200885b68d212159b9d04866ba02ff55c35be247805eec
ToppCellClub-club-1|World / Class top

ST6GALNAC1 VPS13C ADGRG6

1.67e-045488348f80b20b1c4995a0f7084d31666781dce4009a9
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY10 MOV10L1 MYO15A ADGRF1

1.96e-0414588496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWA3A PPP2R2C HIVEP1 FOXJ1

2.17e-04149884a6406c4c9404271a2f4c615c6cd3265b2d759b12
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HOXB6 RALGPS1 RALGPS2 ADGRF1

2.23e-041508844bdcdce40f54580c7a4e1416b468e657ba8874fc
ToppCellMS-CD4-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

ADCY10 VWA3A SYNE2 ANKRD53

2.34e-04152884b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCellAdult-Epithelial-basal_cell-D122|Adult / Lineage, Cell type, age group and donor

ST6GALNAC1 TP63 IL33 ADGRG6

2.46e-0415488438d346402417960044ae999e61f0092b46f2b591
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

HIVEP1 CLCN4 MLYCD FOXJ1

2.52e-04155884a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCellP15-Hematopoietic-Erythroid-enucleate_erythrocyte|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KCNU1 LRRD1 DNAH14

2.76e-04648830c000ac0f2344684ed06e27db3c9415e332a079f
ToppCellP15-Hematopoietic-Erythroid|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KCNU1 LRRD1 DNAH14

2.76e-046488376f10b5420b88ad5260e5e9da656cac3875284da
ToppCellURO-Lymphocyte-T_NK-CD4_TEM|URO / Disease, Lineage and Cell Type

EFCAB6 SYNE2 PDCD4 FOXJ1

2.85e-04160884e406f77b1c1a01d74f39ba65f99d5f8c7d75faf1
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DST TP63 IRAG2 IL33

2.92e-04161884da9eecf919866a9c579d7a707a996cf335213134
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 ANKRD36C ADGRF1 CFB

2.92e-041618849cfbbcd38ec2e75376bbc26001964b6991ad0e21
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DST TP63 IRAG2 IL33

2.92e-04161884d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

DST KCNB1 EEPD1 RABGAP1

2.92e-04161884347edb0de10850b7d16c40945751033289289c9b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD4 TP63 FSCN1 MLYCD

3.06e-04163884bb09e6ca3406eee0593d9a312db7e05934309dd2
ToppCellnormal_Pleural_Fluid-T/NK_cells-CD4+_Th|T/NK_cells / Location, Cell class and cell subclass

FRY CD4 EEPD1 LRRD1

3.13e-04164884334f376350c9cf92611d0f75b2e18a102f4c116a
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT7 CLCN4 ANKRD36C DNAH14

3.13e-04164884c5bfae7e9497185548c243d6f9ebadbcef48ba7f
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT7 CLCN4 ANKRD36C DNAH14

3.13e-0416488476b0ac220b7ca22fbea28a507f01f96ae9f53932
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT7 CLCN4 ANKRD36C DNAH14

3.13e-04164884911081739174ec68bc0893c804e4276b206bea7d
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWA3A KCNB1 RHPN2 FOXJ1

3.13e-041648849e16e52f5a634585f26021bcce9b5d5992ff6db0
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRRN3 HIVEP1 EFCAB6 TP63

3.27e-04166884bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRRN3 HIVEP1 EFCAB6 TP63

3.27e-041668845e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellICU-SEP-Lymphocyte-T_NK-dnT|ICU-SEP / Disease, Lineage and Cell Type

USP36 LRRN3 TRAF3 TRMT44

3.27e-0416688496d92316cee20b722fe782db9dafcceb8f2c220b
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP1 CD4 EEPD1 UGGT1

3.35e-04167884e0f2509e86302eca8352821bce12597f6c51fc24
ToppCellfacs-Lung-EPCAM-24m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP1 CD4 EEPD1 UGGT1

3.35e-04167884b25646b6653cd8814dbeae4c74ce899ede105200
ToppCellcontrol-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYCP2L KRT7 VPS13A MAP10

3.43e-04168884affc39c7568b7df4b36af6f5b0e3702a18b6268c
ToppCellClub_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

ST6GALNAC1 KRT7 ANKRD36C ADGRF1

3.50e-0416988403b303af8a26c6ff196507fe24f5bd3d75d7b1af
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

TMTC3 SYNE2 VPS13A IRAG2

3.50e-04169884bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCell3'_v3-blood-Hematopoietic_progenitors-HSC-MPP|blood / Manually curated celltypes from each tissue

HOXB6 PLPPR3 FSCN1 ADGRG6

3.58e-041708841443d7fccc81088dd42dcbb9361e269872542274
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

SYCP2L KRT7 FRY ZFYVE9

3.58e-0417088497df5ffb328196c46568975d2d97722bcc753bf5
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

ST6GALNAC1 DST ANKRD36C JMJD1C

1.27e-0450564GAVISH_3CA_METAPROGRAM_EPITHELIAL_COLON_RELATED
Diseasefamilial adenomatous polyposis 1 (implicated_via_orthology)

APC2 APC

8.40e-062862DOID:0080409 (implicated_via_orthology)
DiseaseParkinson's disease 23 (implicated_via_orthology)

VPS13C VPS13A

8.40e-062862DOID:0060896 (implicated_via_orthology)
Diseasechoreaacanthocytosis (implicated_via_orthology)

VPS13C VPS13A

8.40e-062862DOID:0050766 (implicated_via_orthology)
Diseaseautosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)

VPS13C VPS13A

2.51e-053862DOID:0111611 (implicated_via_orthology)
DiseaseCohen syndrome (implicated_via_orthology)

VPS13C VPS13A

2.51e-053862DOID:0111590 (implicated_via_orthology)
Diseaseparacoccidioidomycosis (is_marker_for)

IL33 CFB

1.75e-047862DOID:12662 (is_marker_for)
DiseaseEctrodactyly

SEM1 TP63

1.75e-047862C0265554
Diseasecerebellar ataxia (implicated_via_orthology)

VPS13C VPS13A

2.32e-048862DOID:0050753 (implicated_via_orthology)
DiseasePathological accumulation of air in tissues

PPP2R2A PPP2R2C

5.44e-0412862C0013990
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2A PPP2R2C

5.44e-0412862DOID:1441 (implicated_via_orthology)
DiseaseMental Retardation, X-Linked Nonsyndromic

CLCN4 HUWE1

6.41e-0413862C3501611
Diseasequinate measurement

EEPD1 CFB

8.60e-0415862EFO_0021167
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

EEPD1 SYNE2 APOC4 JMJD1C KPNB1

1.07e-03264865EFO_0008317, EFO_0020944
Diseasenon-high density lipoprotein cholesterol measurement

EVI5 TCEA2 HIVEP1 EEPD1 SYNE2 CFB MLYCD KPNB1

1.13e-03713868EFO_0005689
DiseaseColorectal Neoplasms

RHPN2 TP63 APC2 APC KDM2A

1.32e-03277865C0009404
Diseasetransitional cell carcinoma (is_implicated_in)

TP63 APC

1.87e-0322862DOID:2671 (is_implicated_in)
Diseasespermatogenic failure (is_implicated_in)

KCNU1 MOV10L1

2.04e-0323862DOID:0111910 (is_implicated_in)
DiseaseNeoplasm Invasiveness

KRT7 SET EIF4E PDCD4

2.09e-03184864C0027626
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

SYNE2 APOC4 JMJD1C DNAH1

2.82e-03200864EFO_0004611, EFO_0020945

Protein segments in the cluster

PeptideGeneStartEntry
SGISLKLKSKTTSWE

URB2

6

Q14146
KSLQKLVSDWNTLKS

BARGIN

151

Q6ZT62
SLLSTNDKTIKLWKI

PPP2R2C

106

Q9Y2T4
IRIEWLKSKSTKAAT

CDHR1

751

Q96JP9
SLSKKSLNVWNKDSI

C2orf69

201

Q8N8R5
LLSTNDKTIKLWKIS

PPP2R2A

111

P63151
NKLSALSSWKQTEKQ

ADGRF1

851

Q5T601
DWSKTATNIIKKSSD

ADGRG6

1141

Q86SQ4
SKSKESIWEFIKSLL

CLCN4

51

P51793
KTLKKDKSWSQTFES

ADCY10

1116

Q96PN6
LTKAWFLESKDSLLK

APOC4

96

P55056
SKSLDNIWISKSLKK

EEPD1

486

Q7L9B9
LTKTWALLNRKDKTT

RALGPS1

156

Q5JS13
KSRKWLKSILLSDES

INO80

121

Q9ULG1
QLAWKATSVKKDSVS

ANKRD36C

1026

Q5JPF3
SWSTLKTQDQKTVRK

CFB

81

P00751
KVSLKATWTDAESKQ

ANKRD53

41

Q8N9V6
KKTWFNRTLSSIKTA

RABGAP1

1046

Q9Y3P9
LLKKLLFSSEKSSWR

MINDY3

61

Q9H8M7
LVIWKTQSNKLSLTA

LRRD1

811

A4D1F6
VKTRSSWKSLEKSQS

MAP10

831

Q9P2G4
SWKKLKSSQALTSAK

MOV10L1

461

Q9BXT6
SKKLLDSWFTSTQEK

JAGN1

166

Q8N5M9
KLTHKINTESSLWSL

NUDCD3

241

Q8IVD9
TKWTLLQEQKSAKSS

KRT7

121

P08729
SLSKASTAINWLTKK

MYO15A

126

Q9UKN7
SVLKSIEFLSSKWKK

MTO1

541

Q9Y2Z2
KLKSFSDWVSEKSKS

DST

3521

Q03001
LVTSEKTALSWVKKD

JMJD1C

1816

Q15652
DKSKTWQANLRLISK

EIF4E

51

P06730
KLLLSSSEWVQSEKL

MLYCD

376

O95822
LLKSLWKSSTITVDQ

PDCD4

386

Q53EL6
DKVAEKLSSTLSWVK

EVI5

21

O60447
KSSKSTKLQRWDLSG

FAM217B

296

Q9NTX9
SVKFSKLLSIILSTW

KCNU1

221

A8MYU2
TASALTKLLTKGLSW

HUWE1

1101

Q7Z6Z7
SKISLISEKWQKSEA

IKBIP

91

Q70UQ0
ASKWSAESNSLKIIV

KIR3DX1

101

Q9H7L2
WKKESKLLSASQLSA

HOXB6

201

P17509
TAKSATWTYSTELKK

TP63

186

Q9H3D4
ISEQSLSKIKQWALS

DNAH1

406

Q9P2D7
KESTLKSVLSALWNL

APC2

546

O95996
KISTAKWKNTASKAL

IL33

11

O95760
SLDLSWTNISKKQLT

KDM2A

956

Q9Y2K7
NKWKWTKRTLSETSS

KCNB1

486

Q14721
SASSLKKKQIWTLEQ

FSCN1

36

Q16658
LVTKAKNRWSDLSKN

EFCAB6

841

Q5THR3
SSSKSWITFDLKNKE

CD4

246

P01730
ASKATKITLSAIYKW

FOXJ1

136

Q92949
VKSWLLKTSKIISQS

DNAH14

1646

Q0VDD8
KVDLSTSTDWKEAKS

MACROD1

86

Q9BQ69
NKAKTLATWATKELR

KPNB1

856

Q14974
SWATNLKSSIRKANK

IRAG2

481

Q12912
TSTSKITSTAWKNKD

FBXL5

421

Q9UKA1
EISIKYLLKSWSNTS

FRY

11

Q5TBA9
LNKIRSQKSLWTIKS

CEP295

391

Q9C0D2
LASSLKLTSTQVKIW

NKX2-3

181

Q8TAU0
ESSTQDTSKWKRTAK

PCARE

136

A6NGG8
TKTWALLSRKDKTTF

RALGPS2

156

Q86X27
WSVENKKSDFKSTLS

TRMT44

281

Q8IYL2
LNSDISAITTWLKKT

SYNE2

6556

Q8WXH0
SVLVSWKASSKILKS

LRRN3

536

Q9H3W5
WKASSKILKSSVKWT

LRRN3

541

Q9H3W5
SKSTEIKWKSGKDLT

SET

166

Q01105
DSVKIKASKSLWLQK

ST6GALNAC1

281

Q9NSC7
SSTSRKKKWARSLTL

SEM1

76

Q6ZVN7
EVTSLAKSLIKSWKK

TCEA1

61

P23193
NKKLKCTETWSLNSL

WRN

166

Q14191
TKKISKKLSFLSWGT

RHPN2

631

Q8IUC4
KESTLKSVLSALWNL

APC

581

P25054
EKILTTNTWSSELSK

UGDH

206

O60701
NLLKEWSNSLEKKVS

TRAF3

261

Q13114
SSTAHLWEKKDTKTL

VPS13A

1681

Q96RL7
ISNNKKWILSASKDR

WDR88

371

Q6ZMY6
KEKIKWTTTIIISSS

SPO16

6

Q5VVC0
ASRSKQLISEWKQKS

PLPPR3

401

Q6T4P5
ILWQLAKITESSSTK

STAG2

741

Q8N3U4
ELSWTSNQKKKSLKS

SYCP2L

516

Q5T4T6
FTKNKVQLKISTSAW

VPS13C

2811

Q709C8
DKTQKISKKLSFLSW

RHPN2P1

526

A8MT19
SSLWKSKLLVSYQEI

UNC5A

661

Q6ZN44
TQKKWKSLTLSQRAL

ZKSCAN7

241

Q9P0L1
SLIKSWKKLLDASDA

TCEA2

71

Q15560
ISTKSVFKKLSWICL

TMTC3

396

Q6ZXV5
DLLVYSSKWKSSLSK

HIVEP1

2011

P15822
TVSSTLLDTKWNKIL

ZFYVE9

26

O95405
AKKLALSAKKASTLW

USP36

686

Q9P275
LTVLWLFSSVKADSK

UGGT1

31

Q9NYU2
KADSKAITTSLTTKW

UGGT1

41

Q9NYU2
VSASTLQELKLWVKT

VWA3A

226

A6NCI4
KWNSSTSKIKSIELL

ZNF518B

651

Q9C0D4
STFSSSTKKLKEKLW

KIAA1958

501

Q8N8K9
LKRSKSGKSLTQSLW

LRRC51

41

Q96E66