Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	MAGEA3/MAGEA6	MAGEA3 MAGEA6	1.90e-05	2	82	2	IPR030097
Domain	Ig-like_fold	MXRA5 HMCN2 PTPRZ1 SIGLEC8 NFKB1 ICAM4 NFASC DCC KIR3DL1 USH2A IGSF3	2.53e-04	706	82	11	IPR013783
Domain	ENTH	EPN1 EPN2	2.82e-04	6	82	2	PF01417
Domain	IGc2	MXRA5 HMCN2 SIGLEC8 NFASC DCC IGSF3	5.87e-04	235	82	6	SM00408
Domain	Ig_sub2	MXRA5 HMCN2 SIGLEC8 NFASC DCC IGSF3	5.87e-04	235	82	6	IPR003598
Domain	-	MXRA5 PTPRZ1 SIGLEC8 NFKB1 ICAM4 NFASC DCC KIR3DL1 USH2A IGSF3	6.35e-04	663	82	10	2.60.40.10
Domain	ENTH	EPN1 EPN2	6.72e-04	9	82	2	PS50942
Domain	ENTH	EPN1 EPN2	6.72e-04	9	82	2	SM00273
Domain	ENTH	EPN1 EPN2	8.38e-04	10	82	2	IPR013809
Domain	IG_LIKE	MXRA5 HMCN2 SIGLEC8 ICAM4 NFASC DCC KIR3DL1 IGSF3	1.40e-03	491	82	8	PS50835
Domain	Ig_I-set	MXRA5 HMCN2 SIGLEC8 NFASC DCC	1.50e-03	190	82	5	IPR013098
Domain	I-set	MXRA5 HMCN2 SIGLEC8 NFASC DCC	1.50e-03	190	82	5	PF07679
Domain	Ig-like_dom	MXRA5 HMCN2 SIGLEC8 ICAM4 NFASC DCC KIR3DL1 IGSF3	1.63e-03	503	82	8	IPR007110
Domain	IG	MXRA5 HMCN2 SIGLEC8 NFASC DCC KIR3DL1 IGSF3	2.50e-03	421	82	7	SM00409
Domain	Ig_sub	MXRA5 HMCN2 SIGLEC8 NFASC DCC KIR3DL1 IGSF3	2.50e-03	421	82	7	IPR003599
Domain	UIM	EPN1 EPN2	2.78e-03	18	82	2	PF02809
Domain	MAGE_N	MAGEA3 MAGEA6	3.44e-03	20	82	2	SM01392
Domain	UIM	EPN1 EPN2	3.79e-03	21	82	2	SM00726
Domain	MAGE_N	MAGEA3 MAGEA6	4.15e-03	22	82	2	PF12440
Domain	MAGE_N	MAGEA3 MAGEA6	4.15e-03	22	82	2	IPR021072
Domain	UIM	EPN1 EPN2	4.94e-03	24	82	2	PS50330
Domain	C2H2_Znf_fam	ZSCAN32 PLAGL2	4.94e-03	24	82	2	IPR027775
Pubmed	miR-1273g silences MAGEA3/6 to inhibit human colorectal cancer cell growth via activation of AMPK signaling.	MAGEA3 MAGEA6	6.19e-06	2	87	2	30056111
Pubmed	Up-regulation of human bradykinin B1 receptor by secreted components of Pseudomonas aeruginosa via a NF-κB pathway in epithelial cells.	NFKB1 BDKRB1	6.19e-06	2	87	2	22092568
Pubmed	Curvature of clathrin-coated pits driven by epsin.	EPN1 EPN2	6.19e-06	2	87	2	12353027
Pubmed	Ghrelin induces gastric cancer cell proliferation, migration, and invasion through GHS-R/NF-κB signaling pathway.	GHSR NFKB1	6.19e-06	2	87	2	23807739
Pubmed	Targeting tetramer-forming GABPβ isoforms impairs self-renewal of hematopoietic and leukemic stem cells.	GABPB2 GABPB1	6.19e-06	2	87	2	22862946
Pubmed	A Comprehensive Expression Analysis of Cancer Testis Antigens in Head and Neck Squamous Cell Carcinoma Revels MAGEA3/6 as a Marker for Recurrence.	MAGEA3 MAGEA6	6.19e-06	2	87	2	25564441
Pubmed	A unique death pathway keeps RIPK1 D325A mutant mice in check at embryonic day 10.5.	MLKL GSDMD NFKB1	1.20e-05	18	87	3	34437534
Pubmed	Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling.	EPN1 EPN2	1.85e-05	3	87	2	34440686
Pubmed	Netrin-1 promotes glioma growth by activating NF-κB via UNC5A.	NFKB1 DCC	1.85e-05	3	87	2	28710382
Pubmed	Epigenetic silencing of ADAMTS18 promotes cell migration and invasion of breast cancer through AKT and NF-κB signaling.	NFKB1 ADAMTS18	1.85e-05	3	87	2	28503860
Pubmed	A mammalian mirtron miR-1224 promotes tube-formation of human primary endothelial cells by targeting anti-angiogenic factor epsin2.	EPN1 EPN2	1.85e-05	3	87	2	28717225
Pubmed	Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development.	EPN1 EPN2	1.85e-05	3	87	2	32960814
Pubmed	MAPK/NF-κB-dependent upregulation of kinin receptors mediates airway hyperreactivity: a new perspective for the treatment.	NFKB1 BDKRB1	1.85e-05	3	87	2	23428345
Pubmed	Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling.	EPN1 EPN2	1.85e-05	3	87	2	23187125
Pubmed	Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors.	MLKL GSDMD	1.85e-05	3	87	2	36155655
Pubmed	The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress.	NFKB1 ALPK1	1.85e-05	3	87	2	33037203
Pubmed	Interleukin-1 receptor-associated kinase-2 genetic variant rs708035 increases NF-κB activity through promoting TRAF6 ubiquitination.	NFKB1 IRAK2	1.85e-05	3	87	2	24662294
Pubmed	Rubicon-deficiency sensitizes mice to mixed lineage kinase domain-like (MLKL)-mediated kidney ischemia-reperfusion injury.	MLKL GSDMD	1.85e-05	3	87	2	35288534
Pubmed	Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency.	EPN1 EPN2	3.70e-05	4	87	2	24311377
Pubmed	Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease.	NFKB1 IRAK2	3.70e-05	4	87	2	20937840
Pubmed	The epsin family of endocytic adaptors promotes fibrosarcoma migration and invasion.	EPN1 EPN2	3.70e-05	4	87	2	20709745
Pubmed	Epsin-mediated degradation of IP3R1 fuels atherosclerosis.	EPN1 EPN2	3.70e-05	4	87	2	32770009
Pubmed	Degradation of AMPK by a cancer-specific ubiquitin ligase.	MAGEA3 MAGEA6	3.70e-05	4	87	2	25679763
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	TMEM120B DOCK7 IRAK2 GREB1 DCC SMYD2	5.57e-05	265	87	6	19240061
Pubmed	Cloning and analysis of MAGE-1-related genes.	MAGEA3 MAGEA6	6.16e-05	5	87	2	8037761
Pubmed	Irinotecan pharmacogenetics: influence of pharmacodynamic genes.	NFKB1 TDP1	6.16e-05	5	87	2	18347181
Pubmed	Bradykinin enhances cell migration in human chondrosarcoma cells through BK receptor signaling pathways.	NFKB1 BDKRB1	6.16e-05	5	87	2	19885862
Pubmed	Transcriptional up-regulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals.	GABPB2 GABPB1	6.16e-05	5	87	2	9857059
Pubmed	IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination.	NFKB1 IRAK2	6.16e-05	5	87	2	17878161
Pubmed	Intersectin, a novel adaptor protein with two Eps15 homology and five Src homology 3 domains.	EPN1 EPN2	6.16e-05	5	87	2	9813051
Pubmed	Molecular cloning and expression analysis of five novel genes in chromosome 1p36.	UBE4B PTPRZ1	9.22e-05	6	87	2	9653645
Pubmed	IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock.	MLKL GSDMD	9.22e-05	6	87	2	34798063
Pubmed	Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits.	EPN1 EPN2	9.22e-05	6	87	2	25122462
Pubmed	ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis).	MLKL GSDMD	9.22e-05	6	87	2	33109609
Pubmed	Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes.	EPN1 EPN2	9.22e-05	6	87	2	30102256
Pubmed	YEAF1/RYBP and YAF-2 are functionally distinct members of a cofactor family for the YY1 and E4TF1/hGABP transcription factors.	GABPB2 GABPB1	9.22e-05	6	87	2	11953439
Pubmed	Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.	EPN1 EPN2	9.22e-05	6	87	2	25871009
Pubmed	The ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis.	EPN1 EPN2	1.29e-04	7	87	2	18199683
Pubmed	MAGE A1-A6 RT-PCR and MAGE A3 and p16 methylation analysis in induced sputum from patients with lung cancer and non-malignant lung diseases.	MAGEA3 MAGEA6	1.29e-04	7	87	2	22134685
Pubmed	Expression of melanoma-associated antigens in oral squamous cell carcinoma.	MAGEA3 MAGEA6	1.29e-04	7	87	2	18197853
Pubmed	MAGE cancer-testis antigens protect the mammalian germline under environmental stress.	MAGEA3 MAGEA6	1.72e-04	8	87	2	31149633
Pubmed	The Magea gene cluster regulates male germ cell apoptosis without affecting the fertility in mice.	MAGEA3 MAGEA6	1.72e-04	8	87	2	27226137
Pubmed	A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling.	MLKL GSDMD	2.20e-04	9	87	2	32268091
Pubmed	Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.	EPN1 EPN2	2.20e-04	9	87	2	25314967
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PTCD1 ATRNL1 EPB41L5 ALPK1 CLSTN1 EPN2 UTP14C	2.42e-04	493	87	7	15368895
Pubmed	High throughput RNAi screening identifies ID1 as a synthetic sick/lethal gene interacting with the common TP53 mutation R175H.	KLHL10 PTCD1 SATL1	2.56e-04	49	87	3	24378760
Pubmed	Genome-scale RNAi screen for host factors required for HIV replication.	MAGEA3 MAGEA6 HMCN2 GABPB2 NFKB1 GABPB1	2.99e-04	361	87	6	18976975
Pubmed	Comprehensive analysis of DNA repair gene variants and risk of meningioma.	TDG TDP1 FANCA	4.01e-04	57	87	3	18270339
Pubmed	Molecular and genetic characterization of GABP beta.	GABPB2 GABPB1	4.02e-04	12	87	2	7958862
Pubmed	Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.	MLKL GSDMD	4.74e-04	13	87	2	32763970
Pubmed	TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration.	MLKL NFKB1	4.74e-04	13	87	2	31230859
Pubmed	Activity of caspase-8 determines plasticity between cell death pathways.	MLKL GSDMD	5.52e-04	14	87	2	31723262
Pubmed	The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28.	MAGEA3 MAGEA6	5.52e-04	14	87	2	8575766
Pubmed	Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases.	CFH NFKB1	5.52e-04	14	87	2	16519819
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	NDUFAF2 FERMT1 DOCK7 USP43 EPB41L5 IGSF3 EPN2	5.71e-04	569	87	7	30639242
Pubmed	Structure, chromosomal localization, and expression of 12 genes of the MAGE family.	MAGEA3 MAGEA6	6.36e-04	15	87	2	7927540
Pubmed	Mouse models of male infertility.	UTP14C FANCA	8.21e-04	17	87	2	12360237
Pubmed	The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module.	EPN1 EPN2	9.22e-04	18	87	2	10567358
Pubmed	Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities.	ARID1B DCC	9.22e-04	18	87	2	20602751
Pubmed	A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice.	NFKB1 DCC	1.03e-03	19	87	2	11707574
Pubmed	m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs.	YTHDF1 ARID1B	1.03e-03	19	87	2	36039295
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	DMRT3 MAML1 USP43 C15orf39 IGSF3	1.06e-03	307	87	5	37499664
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	CFH UBE4B SZT2 DOCK7 NFASC RXFP4 CLSTN1 USH2A SMYD2	1.11e-03	1031	87	9	16710414
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	YTHDF1 NFKB1 FERMT1 DOCK7 MAML1 C15orf39 ALPK1 EPN1 SAMD4A	1.16e-03	1038	87	9	26673895
Pubmed	Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.	GPLD1 CACFD1	1.26e-03	21	87	2	18940312
Pubmed	Dengue hemorrhagic fever is associated with polymorphisms in JAK1.	CFH NFKB1 NFASC	1.57e-03	91	87	3	20588308
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TMEM120B ZNF585A UBE4B SZT2 MAML1 C15orf39 CACFD1 IGSF3 FANCA	1.78e-03	1105	87	9	35748872
Pubmed	Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.	MLKL GSDMD	1.79e-03	25	87	2	35139355
Pubmed	ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.	MLKL GSDMD	1.79e-03	25	87	2	27917412
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ARID1B SZT2 MAML1 NFASC PLAGL2 IGSF3	2.15e-03	529	87	6	14621295
Pubmed	Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.	ARID1B NFKB1	2.24e-03	28	87	2	30037996
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	UBE4B EPB41L5 FANCA	2.29e-03	104	87	3	31240132
Pubmed	Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.	MLKL GSDMD	2.40e-03	29	87	2	33278357
GeneFamily	Immunoglobulin like domain containing	MXRA5 HMCN2 ICAM4 DCC IGSF3	3.23e-04	193	56	5	594
GeneFamily	Fibronectin type III domain containing	PTPRZ1 NFASC DCC USH2A	1.52e-03	160	56	4	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	MXRA5 HMCN2 NFASC DCC	1.55e-03	161	56	4	593
Coexpression	GSE7768_OVA_WITH_LPS_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN	MLKL HMCN2 GSDMD NFKB1 ICAM4 IRAK2 TCIRG1	1.38e-06	170	85	7	M6855
Coexpression	GSE2585_CTEC_VS_THYMIC_DC_DN	CFH NFKB1 PRSS21 IRAK2 NFASC SSTR5 EPN2	4.05e-06	200	85	7	M6272
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CFH MXRA5 PTPRZ1 ENPP3 SAMD4A FANCA	1.55e-06	182	87	6	03a5a02acd48f0eb210485348bfe0cd21f486215
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MLKL PTPN7 SZT2 NFKB1 TCIRG1 MMP19	2.60e-06	199	87	6	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Mesoderm\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	GSDMD RIN2 ICAM4 USP43 SLC35G2	7.89e-06	139	87	5	d441c29852c28928ecb696b4b95e31b30c17116b
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH MXRA5 PTPRZ1 FERMT1 CLSTN1	1.14e-05	150	87	5	aa11579a57d671a55e64183d35c1340fda6dec14
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRZ1 DCC WDR17 USH2A HYDIN	1.56e-05	160	87	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRZ1 DCC WDR17 USH2A HYDIN	1.56e-05	160	87	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTCD1 PTPRZ1 ATRNL1 NFASC SAMD4A	2.09e-05	170	87	5	fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH MXRA5 PTPRZ1 CLSTN1 IGSF3	2.09e-05	170	87	5	0cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH MXRA5 PTPRZ1 CLSTN1 IGSF3	2.09e-05	170	87	5	2d880223d01bde4bf777bd6f50b7d2768489075f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTCD1 PTPRZ1 ATRNL1 NFASC SAMD4A	2.09e-05	170	87	5	03044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell	E16.5-Epithelial-Epithelial_Airway-Neurosecretory\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DMRT3 PTPRZ1 NFASC SSTR5 GP2	2.40e-05	175	87	5	38dec78efc99fe23479cba68cfa441e62bd6a08b
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	B3GNTL1 GABPB2 EPB41L5 IRAK2 SAMD4A	2.40e-05	175	87	5	711ace94fa9a763c6ae48171a690953f25deebe4
ToppCell	E16.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DMRT3 PTPRZ1 MAST1 NFASC SSTR5	2.60e-05	178	87	5	d3a75a8082e70543b84c35d53fe77625300d19fa
ToppCell	E16.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DMRT3 PTPRZ1 MAST1 NFASC SSTR5	2.60e-05	178	87	5	b2cda1df801b1a1a41e3dd2808baef37765cd804
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 PTPRZ1 EPB41L5 ADAMTS18 GREB1	3.05e-05	184	87	5	6b0c110d8930df99043c3b99cf4d873985126960
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 PTPRZ1 EPB41L5 ADAMTS18 GREB1	3.05e-05	184	87	5	35928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 PTPRZ1 EPB41L5 ADAMTS18 GREB1	3.05e-05	184	87	5	f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NFKB1 ICAM4 MAML1 IRAK2 MMP19	3.56e-05	190	87	5	4d401b73c0e7eb38e95d0851a128bf12bb0d3a9f
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_3\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	HMCN2 ICAM4 FERMT1 BDKRB1 GABPB1	4.22e-05	197	87	5	4f8f23b1ef2eae9d300bd2c1a5cb7ef0163858a1
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	CFH MXRA5 PTPRZ1 FERMT1 CLSTN1	4.22e-05	197	87	5	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Basal_3\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	HMCN2 ICAM4 FERMT1 BDKRB1 GABPB1	4.22e-05	197	87	5	2cff37f9d33951840a8f52ccbba6ca1a4bbe3ad9
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_3-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HMCN2 ICAM4 FERMT1 BDKRB1 GABPB1	4.22e-05	197	87	5	0f37afad46b94c748a149d9ee681472d7a3e6937
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DMRT3 PTPRZ1 ICAM4 FERMT1 SATL1	4.43e-05	199	87	5	e9c47f565a0a7737ecff68569d668aeb707ae5a6
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	YTHDF1 B3GNTL1 FERMT1 SMYD2 FANCA	4.43e-05	199	87	5	cdcdef1d95a8e476de016b1e11ee010438834be0
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PTPRZ1 ATRNL1 FERMT1 USP43 DCC	4.54e-05	200	87	5	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PTPRZ1 ATRNL1 FERMT1 USP43 DCC	4.54e-05	200	87	5	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PTPRZ1 ATRNL1 FERMT1 USP43 DCC	4.54e-05	200	87	5	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PTPRZ1 ATRNL1 FERMT1 USP43 DCC	4.54e-05	200	87	5	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PTPRZ1 ATRNL1 FERMT1 USP43 DCC	4.54e-05	200	87	5	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PTPRZ1 ATRNL1 FERMT1 USP43 DCC	4.54e-05	200	87	5	961858738ce35db8760c8c2e136f8369bc444ccf
Disease	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 measurement	CFH B3GNTL1	7.59e-05	5	82	2	EFO_0802184
Disease	obsolete_interleukin-1 alpha measurement	CFH GRID2IP	1.59e-04	7	82	2	EFO_0802653
Disease	testosterone measurement	GHSR C3P1 ARID1B TMEM120B B3GNTL1 ANAPC1 RIN2 NFKB1 RTL9 USP43 GREB1 USH2A	2.03e-04	1275	82	12	EFO_0004908
Disease	sialic acid-binding Ig-like lectin 6 measurement	CFH SIGLEC8	2.11e-04	8	82	2	EFO_0008285
Disease	eosinophil cationic protein measurement	CFH SPATA31C2	2.11e-04	8	82	2	EFO_0010913
Disease	isovalerate measurement	FAM171A1 USH2A	2.71e-04	9	82	2	EFO_0021051
Disease	interleukin-22 receptor subunit alpha-2 measurement	CFH NFKB1	4.13e-04	11	82	2	EFO_0020500
Disease	ovulation	FAM227A FANCA	1.27e-03	19	82	2	GO_0030728
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	ARID1B NDUFAF2 NFASC DCC NRG3 USH2A SLC14A2 SMYD2	1.73e-03	801	82	8	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	glomerular filtration rate, response to platinum based chemotherapy	NFASC NRG3	2.75e-03	28	82	2	EFO_0004647, EFO_0005208

Protein segments in the cluster

Peptide	Gene	Start	Entry
SGIPNGQWMTQSFTD	TDG	376	Q13569
WSPPSAAMSGLQSGR	nan	46	Q9H8V8
NTMSLWISGTYPSPQ	FAM227A	276	F5H4B4
MASSWPPLELQSSNQ	BDKRB1	1	P46663
TSEGAWPQLPSGLSM	GSDMD	251	P57764
SASSAPPAQEEGMTW	CACFD1	11	Q9UGQ2
YDPINGTPASSTMTW	FERMT1	191	Q9BQL6
VGLSPAQTWPNMTSQ	ARGFX	276	A6NJG6
PLQSSSSEGPQQNMW	ARID1B	1521	Q8NFD5
QTTVTCMENGWSPTP	CFH	426	P08603
PSGSLNWTMGLPTDN	CLSTN1	341	O94985
MSPTLTGNNGVFSWS	ADAMTS18	461	Q8TE60
GNISMLPCSSFTPNW	ALPK1	811	Q96QP1
IATQGPMPNTVSDFW	PTPN7	166	P35236
NSGNIDVPPNMTSWA	ANAPC1	1121	Q9H1A4
PSTQAMPSWPTAAYA	NRG3	216	P56975
PRVSPAMGGQNSSWQ	MAML1	826	Q92585
VSAMTVNGTGPPSNW	DCC	696	P43146
WSPQNASMSESLSIP	FAM171A1	656	Q5VUB5
QGASSLPTTMNYPLW	MAGEA3	66	P43357
QGASSLPTTMNYPLW	MAGEA6	66	P43360
ASLLPSPSVMWASSF	GREB1	1281	Q4ZG55
SSMSVAPWAGAATPL	IRAK2	541	O43187
EATSNDPWGPSSSLM	EPN2	26	O95208
PGSMPNASWTGNLRA	GCNT2	311	Q8N0V5
TCNATGAPSPTLMWL	HMCN2	2006	Q8NDA2
MANGAPFTTDWLGTS	GABPB1	26	Q06547
WSAPSNPVVIMVTGN	KIR3DL1	106	P43629
GSWANFMLTQPHSVS	IGLV6-57	16	P01721
LFTGVPNQPSAAMSW	MMP19	421	Q99542
MNGTPSTAGFLVAWP	GP2	511	P55259
PSMEGNVWFPSSTDI	PTPRZ1	646	P23471
RMPVSPISQGASWAQ	MLKL	121	Q8NB16
ASQHWPFPSGSLMIA	NUDT13	261	Q86X67
WTALSNFSMPSFPGG	MAST1	6	Q9Y2H9
ITWTPMNATSAFGPN	NFASC	746	O94856
QQAWGMRSALPVSPS	EPB41L5	406	Q9HCM4
WPVSATIAFSPQMGH	HYDIN	3686	Q4G0P3
VSWAFNSSLIATMGP	IGSF3	316	O75054
MATTATPATNQGWPE	GRID2IP	1	A4D2P6
SPVANTWRTIPTMFN	KLHL10	501	Q6JEL2
WGSNPSPSAESTQAM	DOCK7	941	Q96N67
PQSWSGEGVISNPAM	C3P1	341	Q6ZMU1
LAQPFQSSEWMPVSS	LINC01599	286	Q8WXQ3
MWNATPSEEPGFNLT	GHSR	1	Q92847
PMWSSYTVPQLGDTS	ENPP3	641	O14638
SSPFLPNDVTLWNTM	DMRT3	381	Q9NQL9
LSPGWTTFYMSTSPN	FAM151A	206	Q8WW52
MSDSWVPNSASGQDP	FANCA	1	O15360
MSPFTNTTLQWLPGE	ATRNL1	826	Q5VV63
EATSNDPWGPSSSLM	EPN1	26	Q9Y6I3
MLAWSPAPTALASGS	ICAM4	231	Q14773
MANVTWPQGPFTTWS	GARIN1A	96	Q6NXP2
MANGAPFTTDWLGTS	GABPB2	26	Q8TAK5
APGSGAMSPWSTQNV	RTL9	366	Q8NET4
MPTLNTSASPPTFFW	RXFP4	1	Q8TDU9
WQQRSTPATMPISAG	SZT2	2821	Q5T011
AVSATQMNVCWSPPT	USH2A	4366	O75445
FISSTPQFWPTPMAQ	SPATA31C2	336	B4DYI2
STFLSGVMLTWPNGP	TMEM120B	196	A0PK00
FSIVPPSNGTTMWRA	SLC35G2	186	Q8TBE7
MSQPGTWQTGLSQPV	SATL1	411	Q86VE3
PPWNLTMTVFQGDAT	SIGLEC8	246	Q9NYZ4
WVPSAPGMFITGDSQ	WDR17	276	Q8IZU2
TWDPMGPGSSIAFTQ	PROB1	521	E7EW31
MEPLFPASTPSWNAS	SSTR5	1	P35346
MTTFFTSVPPWIQDA	PLAGL2	1	Q9UPG8
TSNGPTVIMPTWFCS	B3GNTL1	171	Q67FW5
AMSEGPSSPWTQLAQ	C15orf39	241	Q6ZRI6
QMGLNFWSSPADSKP	RIN2	206	Q8WYP3
MPNAESWPVVGQFSS	TDP1	386	Q9NUW8
NSIPPWSASSSMRGS	USP43	711	Q70EL4
NVDGPNPWMFRSCTS	UTP14C	366	Q5TAP6
NALSGSWASAPPMAS	ZSCAN32	336	Q9NX65
SFWSSVPVMGPSLAS	UBE4B	281	O95155
PPSWMGQNSFLTFIH	TEX52	141	A6NCN8
GVFFSVNSWTPDSMS	GPLD1	326	P80108
APSSTGKTFQPGSWM	NDUFAF2	146	Q8N183
MPANWTSPQKSSALA	ZNF585A	1	Q6P3V2
SDPSGWMVQFGQLTS	PRSS21	91	Q9Y6M0
PMWAPFSSSSSQLPL	PTCD1	41	O75127
SPMVVFGENWNPSET	SMYD2	91	Q9NRG4
QPASAMPNITWSEVQ	SLC14A2	726	Q15849
LWFANPGGSNSMPSR	SAMD4A	641	Q9UPU9
IFPSGWSVAAMANQS	TCIRG1	471	Q13488
GTNVNMPVSKPTSWA	YTHDF1	221	Q9BYJ9
SWSLPDGSLVNSFMQ	MXRA5	2276	Q9NR99
PGTTPLDMATSWQVF	NFKB1	771	P19838