Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22 USP17L15

1.92e-1311422516GO:0004843
GeneOntologyMolecularFunctioncysteine-type peptidase activity

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 CAPN8 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 CAPN11 CAPN7 USP17L22 USP17L15

6.38e-1319222519GO:0008234
GeneOntologyMolecularFunctiondeubiquitinase activity

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22 USP17L15

7.33e-1312422516GO:0101005
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22 USP17L15

3.51e-1213722516GO:0019783
GeneOntologyMolecularFunctionpeptidase activity

USP17L21 USP17L1 USP17L20 PSMB8 USP17L19 USP17L18 CAPN8 USP17L17 ERAP2 ADAMTS16 USP17L3 MYRF CLCA4 DPP10 USP17L12 USP28 USP17L11 USP17L24 USP24 TASP1 USP17L5 USP17L10 CARD8 CAPN11 CAPN7 USP17L22 USP17L15

6.32e-0965422527GO:0008233
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

MYCBP2 TBC1D3I TBC1D3G RASAL2 TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D ITSN1 SH2D3C ARHGAP9 TBC1D3C TBC1D3B MADD TBC1D8 ARHGAP12 AKAP13 ACAP2 CYTH4

7.41e-0850722522GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

MYCBP2 TBC1D3I TBC1D3G RASAL2 TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D ITSN1 SH2D3C ARHGAP9 TBC1D3C TBC1D3B MADD TBC1D8 ARHGAP12 AKAP13 ACAP2 CYTH4

7.41e-0850722522GO:0030695
GeneOntologyMolecularFunctionGTPase activator activity

TBC1D3I TBC1D3G RASAL2 TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D ARHGAP9 TBC1D3C TBC1D3B TBC1D8 ARHGAP12 ACAP2

1.20e-0727922516GO:0005096
GeneOntologyMolecularFunctiondynein light intermediate chain binding

BICD2 DNAH2 DNAH7 DNAH17 DNAH11

1.38e-05282255GO:0051959
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE2 SYNE1 SUN1

1.39e-0552253GO:0140444
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 DNAH7 DNAH17 DNAH11

4.24e-05182254GO:0008569
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAAF5 DNAH2 DNAH7 DNAH17 DNAH11

5.64e-05372255GO:0045505
GeneOntologyMolecularFunctionenzyme activator activity

PIK3CA TBC1D3I TBC1D3G RASAL2 TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D ITSN1 ARHGAP9 TBC1D3C TBC1D3B CARD8 MADD TBC1D8 ARHGAP12 ACAP2

5.68e-0565622520GO:0008047
GeneOntologyMolecularFunctionenzyme regulator activity

MYCBP2 ADGRV1 PIK3CA C3 PARP9 TBC1D3I TBC1D3G RASAL2 TBC1D3K TBC1D3F TBC1D3E TBC1D3 DEPTOR TBC1D3H TBC1D3L TBC1D3D UGT1A7 ITSN1 SH2D3C ARHGAP9 TBC1D3C TBC1D3B PABIR3 CARD8 MADD TBC1D8 CCNF FRY ARHGAP12 AKAP13 ACAP2 CYTH4

1.32e-04141822532GO:0030234
GeneOntologyMolecularFunctionmolecular adaptor activity

WWOX HNRNPU MED24 TDRD3 STXBP1 ANAPC1 SYNE2 AP1G2 AP1M1 PARP9 CAMTA1 HOMER1 BICD2 ANK1 SYNE1 ITSN1 SUN1 SH2D3C CGAS TRIM31 AP1M2 SH2B2 CARD8 SRRT PDLIM1 MYH14 SMARCA2 AKAP13 KLHDC10

6.67e-04135622529GO:0060090
GeneOntologyMolecularFunctioncalcium-dependent cysteine-type endopeptidase activity

CAPN8 CAPN11 CAPN7

8.54e-04172253GO:0004198
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH2 DNAH7 DNAH17 KIF13A DNAH11

1.16e-03702255GO:0003777
GeneOntologyMolecularFunctionlamin binding

DMD SYNE1 SUN1

1.20e-03192253GO:0005521
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

WWOX HNRNPU MED24 TDRD3 SYNE2 AP1G2 AP1M1 PARP9 CAMTA1 HOMER1 BICD2 ANK1 SYNE1 SUN1 SH2D3C CGAS TRIM31 AP1M2 SH2B2 CARD8 SRRT PDLIM1 SMARCA2 AKAP13 KLHDC10

1.43e-03116022525GO:0030674
GeneOntologyBiologicalProcessprotein deubiquitination

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22 USP17L15

5.13e-1312522516GO:0016579
GeneOntologyBiologicalProcessprotein modification by small protein removal

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22 USP17L15

4.72e-1214422516GO:0070646
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D8

2.62e-0910922512GO:0090630
GeneOntologyBiologicalProcessmicrotubule-based transport

ADCY10 IFT172 HNRNPU DST SYNE2 CFAP45 TTLL1 BICD2 SUN1 CCDC39 MADD KIF13A DNAH11

4.47e-0625322513GO:0099111
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

TRPM4 USP17L21 USP17L1 MYCBP2 USP17L20 USP17L19 USP17L18 MED24 USP17L17 UBR5 ANAPC1 USP17L3 TRAF7 SLF1 USP17L12 USP28 USP17L11 USP17L24 USP24 TRIM31 USP17L5 RNF213 USP17L10 CCNF UBE2O KLHDC10 USP17L22 USP17L15

5.59e-06100922528GO:0070647
GeneOntologyBiologicalProcesspost-translational protein modification

TRPM4 USP17L21 USP17L1 MYCBP2 USP17L20 USP17L19 USP17L18 MED24 USP17L17 UBR5 ANAPC1 USP17L3 PARP9 TRAF7 SLF1 USP17L12 USP28 USP17L11 USP17L24 USP24 TRIM31 USP17L5 RNF213 USP17L10 CCNF UBE2O KLHDC10 USP17L22 USP17L15

6.34e-06107422529GO:0043687
GeneOntologyBiologicalProcessmicrotubule-based movement

ADCY10 IFT172 HNRNPU DNAAF5 DST SYNE2 CFAP45 TTLL1 BICD2 SUN1 DNAH2 DNAH7 CCDC39 MADD DNAH17 TEKT4 KIF13A DNAH11

8.49e-0649322518GO:0007018
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D8

1.62e-0524422512GO:0043547
GeneOntologyBiologicalProcessself proteolysis

ADGRV1 CAPN8 CARD8 CAPN7

1.71e-05152254GO:0097264
GeneOntologyBiologicalProcessregulation of GTPase activity

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D ARHGAP9 TBC1D3C TBC1D3B TBC1D8 ARHGAP12

2.02e-0533522514GO:0043087
GeneOntologyBiologicalProcessinner dynein arm assembly

DNAAF5 DNAH2 DNAH7 CCDC39

2.94e-05172254GO:0036159
GeneOntologyBiologicalProcesscilium assembly

IFT172 KIAA0753 CEP350 DNAAF5 SYNE2 ADAMTS16 TTLL1 TBC1D3 SYNE1 FBF1 DNAH2 DNAH7 CCDC39 TBC1D8 DNAH17 TEKT4

3.19e-0544422516GO:0060271
GeneOntologyBiologicalProcessmicrotubule-based process

ADCY10 IFT172 PEX13 CEP76 HNRNPU KIAA0753 CEP350 DNAAF5 DST SYNE2 CFAP45 TTLL1 TBCE BICD2 SUN1 DNAH2 DNAH7 CCDC39 MADD CCNF DNAH17 NINL MACF1 TEKT4 KIF13A NUDC DNAH11

3.65e-05105822527GO:0007017
GeneOntologyBiologicalProcesscilium organization

IFT172 KIAA0753 CEP350 DNAAF5 SYNE2 ADAMTS16 TTLL1 TBC1D3 SYNE1 FBF1 DNAH2 DNAH7 CCDC39 TBC1D8 DNAH17 TEKT4

7.27e-0547622516GO:0044782
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

DNAAF5 DNAH2 DNAH7 CCDC39 DNAH17

8.04e-05412255GO:0070286
GeneOntologyBiologicalProcessnucleus localization

SYNE2 DMD SYNE1 SUN1 NUDC

1.13e-04442255GO:0051647
GeneOntologyBiologicalProcessorganelle assembly

SNF8 IFT172 SPTBN2 CEP76 HNRNPU KIAA0753 CEP350 DNAAF5 NLGN3 MDN1 SYNE2 ADAMTS16 AP1M1 TTLL1 TRAF7 TBC1D3 SYNE1 FBF1 DNAH2 RNF213 DNAH7 CCDC39 TBC1D8 DNAH17 AKAP13 TEKT4 PRKDC

1.24e-04113822527GO:0070925
GeneOntologyCellularComponentspectrin-associated cytoskeleton

SPTA1 SPTB SPTBN2 ANK1

1.64e-0692274GO:0014731
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

USP17L21 USP17L1 USP17L20 MR1 USP17L19 NCLN PTGFRN LRIT3 RYR1 USP17L18 DST USP17L17 ERAP2 SYNE2 OSBPL5 USP17L3 MYRF NOS1 BICD2 USP17L12 USP17L11 SYNE1 UGT1A7 TUSC3 USP17L5 USP17L10 OCA2 GRIN2C POMT1 LRRC8D ABCC12 USP17L22 USP17L15

7.19e-06132722733GO:0042175
GeneOntologyCellularComponentendoplasmic reticulum membrane

USP17L21 USP17L1 USP17L20 MR1 USP17L19 NCLN PTGFRN LRIT3 RYR1 USP17L18 DST USP17L17 ERAP2 SYNE2 OSBPL5 USP17L3 MYRF NOS1 USP17L12 USP17L11 UGT1A7 TUSC3 USP17L5 USP17L10 OCA2 GRIN2C POMT1 LRRC8D ABCC12 USP17L22 USP17L15

2.84e-05129322731GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

USP17L21 USP17L1 USP17L20 MR1 USP17L19 NCLN PTGFRN LRIT3 RYR1 USP17L18 DST USP17L17 ERAP2 SYNE2 OSBPL5 USP17L3 MYRF NOS1 USP17L12 USP17L11 UGT1A7 TUSC3 USP17L5 USP17L10 OCA2 GRIN2C POMT1 LRRC8D ABCC12 USP17L22 USP17L15

3.11e-05129922731GO:0098827
GeneOntologyCellularComponentspectrin

SPTA1 SPTB SPTBN2

1.01e-0492273GO:0008091
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE2 SYNE1 SUN1

1.96e-04112273GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE2 SYNE1 SUN1

1.96e-04112273GO:0106094
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE2 SYNE1 SUN1

1.96e-04112273GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE2 SYNE1 SUN1

1.96e-04112273GO:0034993
GeneOntologyCellularComponentsupramolecular fiber

RYR1 HNRNPU DST SYNJ2 SYNE2 CFAP45 TTLL1 DMD NOS1 HOMER1 TBCE ANK1 SYNE1 FBF1 DNAH2 SH2B2 DNAH7 PDLIM1 MYH14 DNAH17 NINL MACF1 AKAP13 TEKT4 KIF13A NUDC DNAH11

2.06e-04117922727GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

RYR1 HNRNPU DST SYNJ2 SYNE2 CFAP45 TTLL1 DMD NOS1 HOMER1 TBCE ANK1 SYNE1 FBF1 DNAH2 SH2B2 DNAH7 PDLIM1 MYH14 DNAH17 NINL MACF1 AKAP13 TEKT4 KIF13A NUDC DNAH11

2.29e-04118722727GO:0099081
GeneOntologyCellularComponentZ disc

RYR1 DST SYNE2 DMD NOS1 HOMER1 ANK1 PDLIM1

2.51e-041512278GO:0030018
GeneOntologyCellularComponentAP-1 adaptor complex

AP1G2 AP1M1 AP1M2

2.59e-04122273GO:0030121
GeneOntologyCellularComponentI band

RYR1 DST SYNE2 DMD NOS1 HOMER1 ANK1 PDLIM1

4.74e-041662278GO:0031674
GeneOntologyCellularComponentcytoplasmic region

IFT172 HNRNPU DST STXBP1 CFAP45 DNAH2 DNAH7 CCDC39 MADD DNAH17 TEKT4 DNAH11

6.03e-0436022712GO:0099568
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

IFT172 HNRNPU DST CFAP45 DNAH2 DNAH7 CCDC39 MADD DNAH17 TEKT4 DNAH11

7.30e-0431722711GO:0032838
GeneOntologyCellularComponentmicrotubule

HNRNPU DST SYNJ2 CFAP45 TTLL1 TBCE DNAH2 DNAH7 DNAH17 NINL MACF1 TEKT4 KIF13A NUDC DNAH11

7.63e-0453322715GO:0005874
GeneOntologyCellularComponentclathrin coat of trans-Golgi network vesicle

AP1G2 AP1M1 AP1M2

9.14e-04182273GO:0030130
GeneOntologyCellularComponentcell leading edge

ADGRV1 FAT1 DST SYNJ2 PIK3CA SYNE2 DMD CDC42BPG ANK1 ITSN1 SH2D3C SH2B2 MACF1 ACAP2

1.19e-0350022714GO:0031252
GeneOntologyCellularComponentperinuclear region of cytoplasm

SNF8 ADCY10 SPTBN2 ADGRV1 RYR1 FAT1 DST STXBP1 UBR5 SYNJ2 PIK3CA DMD NOS1 TRAF7 SYNE1 PRDX6 CASK CCNF AKAP13 CDC5L GALNT4

1.34e-0393422721GO:0048471
GeneOntologyCellularComponentsarcomere

RYR1 DST SYNE2 DMD NOS1 HOMER1 ANK1 SYNE1 PDLIM1

1.66e-032492279GO:0030017
GeneOntologyCellularComponenttrans-Golgi network transport vesicle membrane

AP1G2 AP1M1 AP1M2

1.67e-03222273GO:0012510
GeneOntologyCellularComponent9+0 motile cilium

CFAP45 DNAH11

1.71e-0362272GO:0097728
GeneOntologyCellularComponentmotile cilium

ADCY10 IFT172 DNAAF5 CFAP45 TTLL1 DNAH2 DNAH7 CCDC39 DNAH17 TEKT4 DNAH11

1.81e-0335522711GO:0031514
GeneOntologyCellularComponentaxoneme

IFT172 CFAP45 DNAH2 DNAH7 CCDC39 DNAH17 TEKT4 DNAH11

1.97e-032072278GO:0005930
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

HNRNPU DST SYNJ2 CFAP45 TTLL1 DMD TBCE FBF1 DNAH2 SH2B2 DNAH7 PDLIM1 DNAH17 NINL MACF1 AKAP13 TEKT4 KIF13A NUDC DNAH11

1.97e-0389922720GO:0099513
GeneOntologyCellularComponentciliary plasm

IFT172 CFAP45 DNAH2 DNAH7 CCDC39 DNAH17 TEKT4 DNAH11

2.03e-032082278GO:0097014
GeneOntologyCellularComponentaxonemal dynein complex

DNAH2 DNAH7 DNAH17

2.44e-03252273GO:0005858
GeneOntologyCellularComponentsarcoplasmic reticulum

RYR1 SYNE2 NOS1 ANK1 POMT1

2.73e-03882275GO:0016529
GeneOntologyCellularComponentdynein complex

DNAH2 DNAH7 DNAH17 DNAH11

2.80e-03542274GO:0030286
GeneOntologyCellularComponentmyofibril

RYR1 DST SYNE2 DMD NOS1 HOMER1 ANK1 SYNE1 PDLIM1

3.08e-032732279GO:0030016
MousePhenoabnormal cellular hemoglobin content

SPTA1 SPTB ANK1 TFR2

8.20e-06121634MP:0008954
DomainHABP4_PAI-RBP1

USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22

2.06e-181622111PF04774
DomainHABP4_PAIRBP1-bd

USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22

2.06e-181622111IPR006861
DomainUSP_CS

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22

1.22e-156622115IPR018200
DomainUCH

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22

3.94e-157122115PF00443
DomainUSP_2

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22

3.94e-157122115PS00973
DomainUSP_3

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22

4.93e-157222115PS50235
DomainUSP_dom

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22

4.93e-157222115IPR028889
DomainPeptidase_C19_UCH

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22

4.93e-157222115IPR001394
DomainUSP_1

USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22

7.51e-147022114PS00972
DomainTBC

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D8

9.75e-124922111SM00164
DomainRabGAP-TBC

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D8

2.45e-115322111PF00566
DomainRab-GTPase-TBC_dom

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D8

3.76e-115522111IPR000195
DomainTBC_RABGAP

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D8

3.76e-115522111PS50086
DomainSpectrin

SPTA1 SPTB SPTBN2 DST SYNE2 DMD SYNE1 MACF1

1.42e-10232218PF00435
DomainSpectrin_repeat

SPTA1 SPTB SPTBN2 DST SYNE2 DMD SYNE1 MACF1

1.17e-09292218IPR002017
DomainSPEC

SPTA1 SPTB SPTBN2 DST SYNE2 DMD SYNE1 MACF1

2.79e-09322218SM00150
DomainSpectrin/alpha-actinin

SPTA1 SPTB SPTBN2 DST SYNE2 DMD SYNE1 MACF1

2.79e-09322218IPR018159
DomainACTININ_2

SPTB SPTBN2 DST SYNE2 DMD SYNE1 MACF1

6.16e-09232217PS00020
DomainACTININ_1

SPTB SPTBN2 DST SYNE2 DMD SYNE1 MACF1

6.16e-09232217PS00019
DomainActinin_actin-bd_CS

SPTB SPTBN2 DST SYNE2 DMD SYNE1 MACF1

6.16e-09232217IPR001589
DomainIRO

IRX5 IRX4 IRX3 IRX1

2.81e-0762214SM00548
DomainIroquois_homeo

IRX5 IRX4 IRX3 IRX1

2.81e-0762214IPR003893
DomainCH

SPTB SPTBN2 DST SYNE2 DMD SYNE1 MACF1

1.15e-05652217SM00033
DomainCH

SPTB SPTBN2 DST SYNE2 DMD SYNE1 MACF1

1.88e-05702217PF00307
Domain-

SPTB SPTBN2 DST SYNE2 DMD SYNE1 MACF1

2.07e-057122171.10.418.10
DomainCH

SPTB SPTBN2 DST SYNE2 DMD SYNE1 MACF1

2.48e-05732217PS50021
DomainCH-domain

SPTB SPTBN2 DST SYNE2 DMD SYNE1 MACF1

2.96e-05752217IPR001715
DomainHomeobox_KN

IRX5 IRX4 IRX3 IRX1

4.02e-05172214PF05920
DomainHomeobox_KN_domain

IRX5 IRX4 IRX3 IRX1

4.02e-05172214IPR008422
Domain-

MYCBP2 UBR5 TECPR1 RCBTB1

1.18e-042222142.130.10.30
DomainPH

SPTBN2 OSBPL5 RASAL2 TECPR1 CDC42BPG ITSN1 ARHGAP9 SH2B2 ARHGAP12 AKAP13 ACAP2 CYTH4

1.24e-0427822112SM00233
DomainPH_DOMAIN

SPTBN2 OSBPL5 RASAL2 TECPR1 CDC42BPG ITSN1 ARHGAP9 SH2B2 ARHGAP12 AKAP13 ACAP2 CYTH4

1.28e-0427922112PS50003
DomainPH_domain

SPTBN2 OSBPL5 RASAL2 TECPR1 CDC42BPG ITSN1 ARHGAP9 SH2B2 ARHGAP12 AKAP13 ACAP2 CYTH4

1.33e-0428022112IPR001849
DomainRCC1/BLIP-II

MYCBP2 UBR5 TECPR1 RCBTB1

1.42e-04232214IPR009091
DomainPH_dom-like

SPTBN2 OSBPL5 PARP9 HOMER1 RASAL2 TECPR1 CDC42BPG ITSN1 ARHGAP9 NBEA SH2B2 ARHGAP12 AKAP13 ACAP2 CYTH4

1.77e-0442622115IPR011993
Domain-

SPTA1 RYR1 CAPN8 DST DMD SLC25A24 ITSN1 CAPN11 TBC1D8 NINL MACF1

2.91e-04261221111.10.238.10
Domaincalpain_III

CAPN8 CAPN11 CAPN7

3.32e-04122213SM00720
DomainC2_III

CAPN8 CAPN11 CAPN7

3.32e-04122213IPR033883
DomainCalpain_III

CAPN8 CAPN11 CAPN7

3.32e-04122213IPR022683
DomainPH

SPTBN2 OSBPL5 CDC42BPG ITSN1 ARHGAP9 SH2B2 ARHGAP12 AKAP13 ACAP2 CYTH4

4.14e-0422922110PF00169
DomainCalpain_III

CAPN8 CAPN11 CAPN7

4.28e-04132213PF01067
DomainCalpain_domain_III

CAPN8 CAPN11 CAPN7

4.28e-04132213IPR022682
DomainEF_hand_dom

SPTA1 RYR1 CAPN8 DST SLC25A24 ITSN1 DNAH7 CAPN11 NINL MACF1

4.59e-0423222110IPR002048
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH7 DNAH11

5.40e-04142213IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH7 DNAH11

5.40e-04142213IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH7 DNAH11

5.40e-04142213IPR013602
DomainDHC_N2

DNAH2 DNAH7 DNAH11

5.40e-04142213PF08393
DomainATPase_dyneun-rel_AAA

MDN1 DNAH2 DNAH11

5.40e-04142213IPR011704
DomainCalpain_cysteine_protease

CAPN8 CAPN11 CAPN7

5.40e-04142213IPR022684
DomainMT

DNAH2 DNAH7 DNAH11

5.40e-04142213PF12777
DomainAAA_8

DNAH2 DNAH7 DNAH11

5.40e-04142213PF12780
DomainAAA_5

MDN1 DNAH2 DNAH11

5.40e-04142213PF07728
DomainEFh

SPTA1 CAPN8 DST SLC25A24 ITSN1 CAPN11 NINL MACF1

5.97e-041582218SM00054
DomainEF-hand-dom_pair

SPTA1 RYR1 CAPN8 DST DMD SLC25A24 ITSN1 CAPN11 TBC1D8 NINL MACF1

6.46e-0428722111IPR011992
DomainDHC_fam

DNAH2 DNAH7 DNAH11

6.69e-04152213IPR026983
DomainPeptidase_C2

CAPN8 CAPN11 CAPN7

6.69e-04152213PF00648
DomainDynein_heavy

DNAH2 DNAH7 DNAH11

6.69e-04152213PF03028
DomainCysPc

CAPN8 CAPN11 CAPN7

6.69e-04152213SM00230
DomainPeptidase_C2_calpain_cat

CAPN8 CAPN11 CAPN7

6.69e-04152213IPR001300
DomainDynein_heavy_dom

DNAH2 DNAH7 DNAH11

6.69e-04152213IPR004273
DomainCALPAIN_CAT

CAPN8 CAPN11 CAPN7

6.69e-04152213PS50203
Domain-

SPTBN2 OSBPL5 HOMER1 RASAL2 TECPR1 CDC42BPG ITSN1 ARHGAP9 SH2B2 ARHGAP12 AKAP13 ACAP2 CYTH4

8.11e-04391221132.30.29.30
DomainKASH

SYNE2 SYNE1

8.23e-0442212IPR012315
DomainKASH

SYNE2 SYNE1

8.23e-0442212PS51049
DomainLRRC37AB_C

LRRC37A3 LRRC37A2

8.23e-0442212IPR029423
DomainSpectrin_bsu

SPTB SPTBN2

8.23e-0442212IPR016343
DomainKASH

SYNE2 SYNE1

8.23e-0442212SM01249
DomainLRRC37AB_C

LRRC37A3 LRRC37A2

8.23e-0442212PF14914
DomainKASH

SYNE2 SYNE1

8.23e-0442212PF10541
DomainLRRC37_N

LRRC37A3 LRRC37A2

8.23e-0442212IPR032754
DomainLRRC37

LRRC37A3 LRRC37A2

8.23e-0442212PF15779
DomainLRRC37A/B-like

LRRC37A3 LRRC37A2

8.23e-0442212IPR015753
DomainRho_GTPase_act

ARHGAP9 ARHGAP12

8.23e-0442212IPR015767
DomainEF_Hand_1_Ca_BS

CAPN8 DST SLC25A24 ITSN1 DNAH7 CAPN11 NINL MACF1

1.16e-031752218IPR018247
DomainAAA

ABCA13 MDN1 DNAH2 RNF213 DNAH7 ABCC12 DNAH11

1.65e-031442217SM00382
DomainAAA+_ATPase

ABCA13 MDN1 DNAH2 RNF213 DNAH7 ABCC12 DNAH11

1.65e-031442217IPR003593
Domain-

DST MACF1

2.03e-03622123.90.1290.10
DomainClathrin_mu_CS

AP1M1 AP1M2

2.03e-0362212IPR018240
DomainCLAT_ADAPTOR_M_1

AP1M1 AP1M2

2.03e-0362212PS00990
DomainCLAT_ADAPTOR_M_2

AP1M1 AP1M2

2.03e-0362212PS00991
DomainGAR

DST MACF1

2.03e-0362212PS51460
DomainGAS2

DST MACF1

2.03e-0362212PF02187
Domain-

DST MACF1

2.03e-03622123.30.920.20
DomainGAS_dom

DST MACF1

2.03e-0362212IPR003108
DomainGAS2

DST MACF1

2.03e-0362212SM00243
DomainPlectin

DST MACF1

2.81e-0372212PF00681
DomainPlectin_repeat

DST MACF1

2.81e-0372212IPR001101
DomainPLEC

DST MACF1

2.81e-0372212SM00250
PathwayREACTOME_RAS_PROCESSING

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

6.36e-154517713MM15671
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L21 USP17L1 USP17L20 PSMB8 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP24 USP17L5 USP17L10 USP17L22 USP17L15

2.25e-0919117716MM15289
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L21 USP17L1 USP17L20 PSMB8 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22 USP17L15

2.57e-0922117717M27578
PathwayREACTOME_MAPK_FAMILY_SIGNALING_CASCADES

USP17L21 USP17L1 USP17L20 SPTA1 SPTB SPTBN2 PSMB8 USP17L19 USP17L18 USP17L17 PIK3CA USP17L3 RASAL2 VWF USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

3.20e-0931817720MM15278
PathwayREACTOME_DEUBIQUITINATION

USP17L21 USP17L1 USP17L20 PSMB8 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP24 USP17L5 USP17L10 USP17L22 USP17L15

1.96e-0726217716MM15286
PathwayREACTOME_DEUBIQUITINATION

USP17L21 USP17L1 USP17L20 PSMB8 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP28 USP17L11 USP17L24 USP24 USP17L5 USP17L10 USP17L22 USP17L15

2.22e-0729917717M27574
PathwayWP_17Q12_COPY_NUMBER_VARIATION_SYNDROME

TBC1D3I TBC1D3G TBC1D3K TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B

4.15e-06991779M46448
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTA1 SPTB SPTBN2 ANK1

4.76e-06101774MM15112
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

NLGN3 STXBP1 HOMER1 GRIN2C SYT10 CASK

6.95e-05561776M27616
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

GALNT15 USP17L21 USP17L1 NANP USP17L20 SPTA1 SPTB SPTBN2 PSMB8 PEX13 USP17L19 USP17L18 USP17L17 ADAMTS16 USP17L3 C3 TTLL1 ANK1 USP17L12 USP28 USP17L11 TUSC3 USP17L24 USP24 NUP88 USP17L5 USP17L10 POMT1 CCNF A4GNT ZNF350 PRKDC USP17L22 USP17L15 GALNT4

1.54e-04147517735M19806
Pubmed

TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

7.92e-25112291116863688
Pubmed

DUB-1, a deubiquitinating enzyme with growth-suppressing activity.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

6.02e-2421229138622927
Pubmed

DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

6.02e-24212291314583620
Pubmed

DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

6.02e-24212291311468161
Pubmed

The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

6.02e-2421229138756639
Pubmed

Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

6.02e-24212291312447969
Pubmed

DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

6.02e-24212291318980247
Pubmed

JAK2 is required for induction of the murine DUB-1 gene.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

1.46e-2322229139154835
Pubmed

DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

7.26e-2324229138995226
Pubmed

Cdc25A and Dub3 in a high-stakes balancing act.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

1.41e-22332291420228807
Pubmed

Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

1.50e-22252291321115691
Pubmed

The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

2.39e-22342291420403174
Pubmed

DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

2.39e-22342291414699124
Pubmed

The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

2.39e-22342291415780755
Pubmed

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

2.39e-22342291419188362
Pubmed

Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

2.39e-22342291411941478
Pubmed

Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

2.39e-22342291417109758
Pubmed

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

2.39e-22342291420388806
Pubmed

Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

2.39e-22342291420715989
Pubmed

Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

2.39e-2234229149806828
Pubmed

The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

2.39e-22342291420368735
Pubmed

The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

2.39e-22342291410936051
Pubmed

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

2.39e-22342291421448158
Pubmed

Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

2.99e-22262291335816173
Pubmed

Cytokine-regulated protein degradation by the ubiquitination system.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

3.95e-22352291416611142
Pubmed

Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

3.95e-22352291421239494
Pubmed

The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

6.43e-22362291420147298
Pubmed

Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

1.03e-21372291420228808
Pubmed

Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

1.92e-21292291332527007
Pubmed

DUX is a non-essential synchronizer of zygotic genome activation.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

8.87e-18502291331806660
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

EPRS1 SPTBN2 OIP5 RYR1 HNRNPU TDRD3 DST MDN1 USP17L3 NCR1 CDC42BPG ANK1 USP17L12 ITSN1 DNAH2 RNF213 ARHGAP9 NBEA CCDC39 FRY PDLIM1 AKAP13 PRKDC RBM41

1.54e-107362292429676528
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ILF3 MYCBP2 SPTBN2 HNRNPU NLGN3 TDRD3 FARSA DST MDN1 UBR5 ANAPC1 SYNE2 NOS1 KCNT1 HOMER1 RASAL2 DMXL2 USP28 SYNE1 ITSN1 DPYSL4 NBEA CASK FRY UBE2O MACF1 CDC5L

2.93e-109632292728671696
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

LRRC37A2 TBC1D3G TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3D RNF213 TBC1D3B

1.51e-0974229916625196
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

EPRS1 ILF3 SPTA1 SPTB SPTBN2 HNRNPU NLGN3 FARSA DST STXBP1 DMD NOS1 HOMER1 RASAL2 CKMT1A DMXL2 VWF OXR1 SYNE1 ITSN1 DPYSL4 NBEA OGDH PRDX6 MADD CASK SRRT UBE2O MYH14 MACF1 CDC5L DNAH11

1.65e-0914312293237142655
Pubmed

Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart.

IRX5 IRX4 VWF IRX3 IRX1

5.30e-0911229510926765
Pubmed

Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos.

IRX5 IRX4 IRX3 IRX1

2.72e-086229420408909
Pubmed

Organization of mouse Iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development.

IRX5 IRX4 IRX3 IRX1

2.72e-086229411042145
Pubmed

Iroquois homeobox 3 regulates odontoblast proliferation and differentiation mediated by Wnt5a expression.

IRX5 IRX4 IRX3 IRX1

2.72e-086229436773339
Pubmed

Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast.

IRX5 IRX4 IRX3 IRX1

2.72e-086229410370142
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

EPRS1 MYCBP2 IFT172 SPTB SPTBN2 CEP350 WDR3 DST STXBP1 RASAL2 BICD2 DMXL2 VWF OXR1 USP28 SYNE1 ITSN1 NBEA MADD CASK FRY UBE2O GTF3A MYH14 RCBTB1 MACF1 ZNF350 PRKDC

3.28e-0812852292835914814
Pubmed

The prepattern transcription factor Irx3 directs nephron segment identity.

IRX5 IRX4 IRX3 IRX1

6.31e-087229417875669
Pubmed

Sensitive nonradioactive detection of mRNA in tissue sections: novel application of the whole-mount in situ hybridization protocol.

IRX5 IRX4 IRX3 IRX1

1.26e-078229411118473
Pubmed

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 NLGN3 CLCN5 USP17L17 NYNRIN CFAP45 USP17L3 ANK1 USP17L12 USP17L11 USP17L5 USP17L10 IRAK3 USP17L22 USP17L15

1.34e-076742291937196079
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

IFT172 DST SYNE1 DNAH17 MACF1

1.69e-0720229521689717
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DCAKD TRPM4 WWOX MYCBP2 SPTB ADGRV1 HNRNPU DNAAF5 NLGN3 PTPRB SYNJ2 OSBPL5 CAMTA1 FAM149A CDC42BPG DEPTOR TUSC3 RNF213 POMT1 TEP1 OGDH LRRC8D PRDX6 CASK MYH14 SMARCA2 LRP5 MACF1 AKAP13

1.98e-0714892292928611215
Pubmed

The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice.

IRX5 IRX4 IRX3 IRX1

2.25e-079229414585979
Pubmed

Gene and cluster-specific expression of the Iroquois family members during mouse development.

IRX5 IRX4 IRX3 IRX1

2.25e-079229411520674
Pubmed

The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.

SYNE2 SYNE1 SUN1

2.82e-073229316079285
Pubmed

Spectrin's E2/E3 ubiquitin conjugating/ligating activity is diminished in sickle cells.

SPTA1 SPTB ANK1

2.82e-073229315929114
Pubmed

Changing patterns in cytoskeletal mRNA expression and protein synthesis during murine erythropoiesis in vivo.

SPTA1 SPTB ANK1

2.82e-07322931385865
Pubmed

Inherited hemolytic disease in mice: a review and update.

SPTA1 SPTB ANK1

2.82e-07322936763106
Pubmed

The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia.

IRX5 IRX3 IRX1

2.82e-073229335328612
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

EPRS1 ILF3 SPTA1 SPTBN2 HNRNPU C4orf17 ACSM3 DST MDN1 STXBP1 CLCN5 SYNE2 CFAP45 TTLL1 DMD SYNE1 ITSN1 FBF1 DNAH2 OGDH CAPN11 MYH14 BAZ1A ARHGAP12 MACF1 IRAK3 ZNF350 PRKDC

3.47e-0714422292835575683
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

EPRS1 ILF3 MYCBP2 SPTBN2 NCLN HNRNPU CEP350 WDR3 DST MDN1 UBR5 SYNE2 SYNE1 SUN1 PRDX6 SRRT PDLIM1 MYH14 BAZ1A MACF1 PRKDC CDC5L NUDC

3.57e-0710242292324711643
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TRPM4 PCNX3 MYCBP2 NCLN RYR1 TDRD3 FAT1 DST MDN1 OSBPL5 AP1G2 MYRF TRAF7 TASP1 LRRK1 TEP1 SH2B2 MADD TKFC NINL LRP5 AKAP13 PRKDC CYTH4

3.58e-0711052292435748872
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

SPTA1 SPTB SPTBN2 ANK1

3.73e-0710229422159418
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SPTA1 SPTB HNRNPU DST SYNE2 DMD SYNE1 RNF213 MYH14 NINL

5.14e-071872291026460568
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

MYCBP2 CEP350 MDN1 UBR5 RNF213 MACF1 PRKDC

7.28e-0776229727542412
Pubmed

SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.

SYNE2 SYNE1 SUN1

1.12e-064229316648470
Pubmed

The membrane attachment protein for spectrin is associated with band 3 in human erythrocyte membranes.

SPTA1 SPTB ANK1

1.12e-0642293379653
Pubmed

Clinical manifestation and phenotypic analysis of novel gene mutation in 28 Chinese children with hereditary spherocytosis.

SPTA1 SPTB ANK1

1.12e-064229333620149
Pubmed

Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.

SYNE2 SYNE1 SUN1

1.12e-064229328716842
Pubmed

iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin.

RYR1 DMD NOS1

1.12e-064229332693782
Pubmed

LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.

SYNE2 SYNE1 SUN1

1.12e-064229323071752
Pubmed

PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.

TBC1D3F TBC1D3 TBC1D3D

1.12e-064229312359748
Pubmed

Spectrin deficient inherited hemolytic anemias in the mouse: characterization by spectrin synthesis and mRNA activity in reticulocytes.

SPTA1 SPTB ANK1

1.12e-06422936234993
Pubmed

Apparent structural differences at the tetramerization region of erythroid and nonerythroid beta spectrin as discriminated by phage displayed scFvs.

SPTA1 SPTB SPTBN2

1.12e-064229321412925
Pubmed

Erythroid phosphatidyl serine exposure is not predictive of thrombotic risk in mice with hemolytic anemia.

SPTA1 SPTB ANK1

1.12e-064229310772878
Pubmed

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.

SYNE2 SYNE1 SUN1

1.12e-064229320108321
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

DST DMD MACF1

1.12e-06422938954775
Pubmed

Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.

TBC1D3F TBC1D3 TBC1D3D

1.12e-06422938406013
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

USP17L21 USP17L20 USP17L19 USP17L18 DNAAF5 USP17L17 USP17L12 USP17L11

1.31e-06119229828625976
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

LRRC37A3 NCLN RYR1 CEP350 MDN1 STXBP1 SYNE2 RASAL2 FAM149A FBF1 USP24 DNAH2 NBEA DNAH7 SMARCA2 IRAK3 DNAH11

1.34e-066382291731182584
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

TRPM4 APTX PTGFRN PGGT1B F13A1 ACSM3 CLCN5 UBR5 SYNJ2 MYRF RASAL2 SYNE1 POMT1 MADD TBC1D8 MACF1 KIF13A ACAP2

1.58e-067192291835337019
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH2 DNAH7 DNAH17 DNAH11

1.74e-061422949373155
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYCBP2 ADGRV1 DST UBR5 SYNE2 CAMTA1 DMXL2 SYNE1 MACF1 CDC5L

2.74e-062252291012168954
Pubmed

The Tre2 (USP6) oncogene is a hominoid-specific gene.

TBC1D3 TBC1D3D TBC1D3C

2.79e-065229312604796
Pubmed

Iroquois genes influence proximo-distal morphogenesis during rat lung development.

IRX5 IRX3 IRX1

2.79e-065229316299054
Pubmed

LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.

SYNE2 SYNE1 SUN1

2.79e-065229322632968
Pubmed

Expression of two novel mouse Iroquois homeobox genes during neurogenesis.

IRX5 IRX3 IRX1

2.79e-065229310704856
Pubmed

Major erythrocyte membrane protein genes in EKLF-deficient mice.

SPTA1 SPTB ANK1

2.79e-065229316728274
Pubmed

Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.

TBC1D3F TBC1D3 TBC1D3D

2.79e-06522938471161
Pubmed

Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

SYNE2 SYNE1 SUN1

2.79e-065229318396275
Pubmed

Expression of Irx6 during mouse morphogenesis.

IRX5 IRX4 IRX3

2.79e-065229311335133
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

GALNT15 ADGRV1 NCLN C4orf17 TDRD3 SYNE2 OSBPL5 TTLL1 TBC1D3F SLC25A24 TRAF7 TBC1D3 SLF1 DEPTOR TBC1D3D SRRT RCBTB1 NUDC

2.84e-067502291811230166
Pubmed

Defining the membrane proteome of NK cells.

DCAKD EPRS1 ILF3 MYCBP2 PEX13 NCLN HNRNPU CEP350 FARSA MDN1 CLCN5 UBR5 OSBPL5 AP1M1 PARP9 RNF213 LRRC8D PRDX6 MYH14 AKAP13 PRKDC CDC5L ACAP2

3.30e-0611682292319946888
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

DST NYNRIN OSBPL5 ZNF282 TECPR1 SYNE1 DNAH2 DNAH7 KLHDC10 DNAH11

3.74e-062332291037704626
Pubmed

A human MAP kinase interactome.

SPTBN2 CEP350 DST SYNJ2 NFYC DMD TBC1D3F VWF SYNE1 ITSN1 MADD MACF1 AKAP13 PRKDC

4.88e-064862291420936779
Pubmed

A novel ENU-induced ankyrin-1 mutation impairs parasite invasion and increases erythrocyte clearance during malaria infection in mice.

SPTA1 SPTB ANK1

5.55e-066229327848995
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

SPTBN2 NLGN3 UBR5 HOMER1 RASAL2 DMXL2 SYNE1 NBEA UBE2O MACF1

7.21e-062512291027507650
Pubmed

CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.

CFAP45 DNAH17 DNAH11

9.67e-067229333139725
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH2 DNAH17 DNAH11

9.67e-067229331178125
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

SNF8 LRRC37A3 APTX SPTBN2 HNRNPU TDRD3 AP1G2 AP1M1 TBCE USP28 ITSN1 POMT1 PRDX6 MADD CASK BAZ1A KIF13A ACAP2 FILIP1L

1.37e-059252291928986522
Pubmed

Identification of a novel mouse Iroquois homeobox gene, Irx5, and chromosomal localisation of all members of the mouse Iroquois gene family.

IRX5 IRX3 IRX1

1.54e-058229310822268
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

ZCWPW2 FAT1 MDN1 ANAPC1 SYNE2 RASAL2 ERVK13-1 DNAH7

1.83e-05170229823314748
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

SPTBN2 NLGN3 STXBP1 UBR5 HOMER1 RASAL2 DMXL2 SYNE1 NBEA MACF1

1.92e-052812291028706196
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

EPRS1 ILF3 WWOX HNRNPU FARSA DST RASAL2 TBCE USP24 PRDX6 TBC1D8 PDLIM1 ARHGAP12 MACF1 PRKDC NUDC

2.14e-057082291639231216
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

MYCBP2 DST STXBP1 TMEM163 ADGRL3 DMXL2 OXR1 ITSN1 NBEA MADD MACF1

2.15e-053472291117114649
Pubmed

A Noncanonical Role of Fructose-1, 6-Bisphosphatase 1 Is Essential for Inhibition of Notch1 in Breast Cancer.

EPRS1 ILF3 HNRNPU SLC25A24 PRDX6 SRRT MYH14 SMARCA2 PRKDC CDC5L

2.23e-052862291032041737
Pubmed

The highly conserved C-terminal dileucine motif in the cytosolic domain of the human immunodeficiency virus type 1 envelope glycoprotein is critical for its association with the AP-1 clathrin adaptor [correction of adapter].

AP1G2 AP1M1 AP1M2

2.30e-059229311222723
Cytoband4p16.1

USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

6.77e-1579229124p16.1
CytobandEnsembl 112 genes in cytogenetic band chr17q12

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

2.82e-1014922911chr17q12
CytobandEnsembl 112 genes in cytogenetic band chr4p16

USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

1.56e-0922222912chr4p16
Cytoband17q12

TBC1D3F TBC1D3 TBC1D3H TBC1D3C TBC1D3B

1.44e-0499229517q12
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SPTB SPTBN2 OSBPL5 RASAL2 CDC42BPG ITSN1 ARHGAP9 SH2B2 ARHGAP12 AKAP13 ACAP2 CYTH4

4.34e-0820613412682
GeneFamilyDyneins, axonemal

DNAH2 DNAH7 DNAH17 DNAH11

6.37e-06171344536
GeneFamilyEF-hand domain containing|Spectrins

SPTA1 SPTB SPTBN2

1.36e-05713431113
GeneFamilyEF-hand domain containing

SPTA1 CAPN8 DST SLC25A24 ITSN1 DNAH7 CAPN11 NINL MACF1

3.75e-052191349863
GeneFamilyTALE class homeoboxes and pseudogenes

IRX5 IRX4 IRX3 IRX1

3.80e-05261344526
GeneFamilyC2 domain containing|Calpains

CAPN8 CAPN11 CAPN7

1.70e-04151343975
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE2 SYNE1

3.24e-04413421252
GeneFamilyNudC family

NUDCD1 NUDC

3.24e-04413421285
GeneFamilyEF-hand domain containing|Plakins

DST MACF1

1.48e-0381342939
GeneFamilyWD repeat domain containing

IFT172 WDR3 TRAF7 DMXL2 NBEA TEP1 WDR97

3.42e-032621347362
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 MED24 USP17L17 USP17L3 HOMER1 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

5.09e-1411222615MM1095
CoexpressionMADAN_DPPA4_TARGETS

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

5.14e-138622613MM1312
CoexpressionGERY_CEBP_TARGETS

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 C3 USP17L12 USP17L11 USP17L5 USP17L10 USP17L22 USP17L15

1.27e-1016022614MM1155
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

MYCBP2 CEP350 TDRD3 FAT1 DST MDN1 UBR5 SYNJ2 SYNE2 NFYC DMD HOMER1 SLC25A24 DMXL2 ITSN1 USP24 CASK BAZ1A ARHGAP12 SMARCA2 MACF1 AKAP13 KLHDC10 ACAP2 FILIP1L

1.16e-0785622625M4500
CoexpressionGSE16385_IL4_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP

EPRS1 ILF3 CCDC18 WDR3 HSF2 SUN1 TEP1 GTF3A SMARCA2 MACF1 PRKDC FILIP1L

1.33e-0719422612M8017
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP

SNF8 USP17L21 USP17L1 USP17L20 USP17L19 ACOX2 USP17L18 USP17L17 USP17L3 TTLL1 USP17L12 USP17L11 SH2D3C USP17L5 USP17L10 TBC1D8 UBE2O TKFC PDLIM1 USP17L22 USP17L15

2.31e-0764722621MM981
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP

EPRS1 PSMB8 PEX13 CEP350 WDR3 TDRD3 MDN1 UBR5 ERAP2 PIK3CA SYNE2 NFYC HSF2 DMXL2 OXR1 SUN1 LRRC8D PRDX6 CARD8 GTF3A BAZ1A CAPN7 ARHGAP12 MACF1 ZFTA PRKDC KLHDC10 RBM41

2.28e-06121522628M41122
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

MYCBP2 CEP350 FAT1 DST MDN1 UBR5 NFYC HOMER1 ITSN1 USP24 CASK BAZ1A ARHGAP12 SMARCA2 FILIP1L

1.43e-0546622615M13522
CoexpressionLAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2

WWOX ACSM3 SYNE2 RASAL2 OXR1 ITSN1 RNF213 NBEA AKAP13

2.35e-051762269M39223
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

MYCBP2 SPTBN2 FNDC5 IRX4 PTPRB KCNT1 DOC2B DPP10 ANK1 COMP DPYSL4 GRIN2C IRX1 SYT10

2.99e-0543822614M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

MYCBP2 SPTBN2 FNDC5 IRX4 PTPRB KCNT1 DOC2B DPP10 ANK1 COMP DPYSL4 GRIN2C IRX1 SYT10

3.14e-0544022614MM832
CoexpressionGSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_UP

TRPM4 F13A1 DST GVINP1 HOMER1 SYNE1 SYT10 FRY

5.46e-051522268M2964
CoexpressionGSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_UP

EPRS1 ZCWPW2 CCDC18 HOMER1 TRAF7 TEP1 GTF3A PRKDC CYTH4

5.66e-051972269M8022
CoexpressionMARSON_BOUND_BY_FOXP3_STIMULATED

USP17L21 USP17L1 USP17L20 KDM5C CCDC18 USP17L19 HNRNPU USP17L18 USP17L17 SYNJ2 USP17L3 TBCE SLC25A24 USP17L12 USP17L11 CGAS USP17L5 USP17L10 LRRC8D PRDX6 ARHGAP12 USP17L22 USP17L15

5.84e-05107222623MM1031
CoexpressionGSE22886_TH1_VS_TH2_12H_ACT_UP

TRPM4 NCLN STXBP1 CAMTA1 BICD2 AP1M2 NBEA TFR2 KLHDC10

6.12e-051992269M4507
CoexpressionGSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP

TRPM4 SYNE2 AP1G2 TTLL1 PARP9 NCR1 CCDC39 PDLIM1 GALNT4

6.36e-052002269M331
CoexpressionGSE16450_CTRL_VS_IFNA_12H_STIM_MATURE_NEURON_CELL_LINE_UP

ZCWPW2 CCDC18 ADGRV1 ACOX2 ACSM3 ZNF282 SH2B2 CCDC39 RCBTB1

6.36e-052002269M7411
CoexpressionGSE37534_PIOGLITAZONE_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN

KDM5C APTX UBR5 OSBPL5 AP1M2 OCA2 FRY RBM41

9.71e-051652268M8992
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05

TBC1D3G TBC1D3K TBC1D3F TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

3.04e-07902139PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlasDE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05

C3 TBC1D3G MYRF TBC1D3K TBC1D3F VWF TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B NINL

1.09e-0624221313PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05

C3 TBC1D3G MYRF TBC1D3K TBC1D3F VWF TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

1.73e-0621321312PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

C3 TBC1D3G MYRF TBC1D3K TBC1D3F VWF TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

1.73e-0621321312PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

PRTG TBC1D3G MYRF TBC1D3K TBC1D3F VWF TBC1D3 TBC1D3H TBC1D3L TBC1D3D IRX3 TBC1D3C TBC1D3B

2.25e-0532021313PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#3

IRX5 MR1 F13A1 ADGRL3 CKMT1A DNAH2 RNF213 NBEA IRX3 MYH14 FILIP1L

3.02e-0523821311Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000_K3
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5

IRX5 MR1 PTGFRN F13A1 OLFML2A OSBPL5 ADGRL3 TBCE TECPR1 CKMT1A DOC2B SYNE1 DNAH2 RNF213 NBEA IRX3 PIEZO2 MYH14 AKAP13 FILIP1L

4.59e-0572621320Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlasStem Cells, SC.LTSL.BM, CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-1

F13A1 DST STXBP1 NYNRIN SYNE2 C3 DMXL2 VWF DEPTOR ITSN1 NBEA TFR2 TBC1D8 IRAK3

7.07e-0540921314GSM476663_500
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

PRTG TBC1D3G TBC1D3K TBC1D3F TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B PABIR3

1.34e-0428121311PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

PRTG TBC1D3G TBC1D3K TBC1D3F TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B PABIR3

1.34e-0428121311PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000

ZNF184 CCDC18 MR1 F13A1 HNRNPU TMEM163 DMD ADGRL3 CKMT1A FAM149A DOC2B VWF ANK1 DNAH2 RNF213 DPYSL4 LRRC8D EIF4E1B GTF3A MYH14 BAZ1A MACF1 FILIP1L

1.36e-0497821323Facebase_RNAseq_e10.5_Mandibular Arch_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000

APTX SPTBN2 MR1 ADGRV1 SYNE2 TMEM163 DMD ADGRL3 RASAL2 CKMT1A DOC2B VWF DNAH2 AP1M2 RNF213 DPYSL4 LRRC8D PDLIM1 MYH14 BAZ1A NINL MACF1 FILIP1L

1.49e-0498421323Facebase_RNAseq_e10.5_Olfactory Pit_1000
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

TRPM4 SPTB PEX13 RYR1 NLGN3 CLCN5 NOS1 DMXL2 TBC1D3L ITSN1 LRRK1 TBC1D8 PIEZO2 FILIP1L

1.44e-1219722214a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

TRPM4 SPTB PEX13 RYR1 NLGN3 CLCN5 NOS1 DMXL2 TBC1D3L ITSN1 LRRK1 TBC1D8 PIEZO2 FILIP1L

1.44e-121972221415b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 SPTA1 ADGRV1 CAPN8 FAT1 ADAMTS16 DMD ADGRL3 ANK1 PIEZO2 DNAH11

2.36e-09184222112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 SPTA1 ADGRV1 CAPN8 FAT1 ADAMTS16 DMD ADGRL3 ANK1 PIEZO2 DNAH11

2.36e-09184222112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 SPTA1 ADGRV1 CAPN8 FAT1 ADAMTS16 DMD ADGRL3 ANK1 PIEZO2 DNAH11

2.36e-0918422211ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PTPRB DST STXBP1 UBR5 SYNE2 ADGRL3 DOC2B VWF SLF1 RNF213 MACF1

5.65e-0920022211dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 FAT1 TMEM163 ADGRL3 OXR1 SYNE1 IRX3 SYT10 DNAH17 DNAH11

2.07e-0817622210327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IRX5 ABCA13 FAT1 SYNE2 ADGRL3 DEPTOR OXR1 IRX3 DNAH7 DNAH11

4.07e-0818922210904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IRX5 ABCA13 FAT1 SYNE2 HOMER1 ADGRL3 DEPTOR OXR1 IRX3 DNAH7

4.50e-0819122210d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PTPRB DST STXBP1 SYNE2 ADGRL3 DOC2B VWF SH2D3C RNF213 MACF1

6.93e-08200222105c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / Treatment groups by lineage, cell group, cell type

PTPRB DST SYNJ2 SYNE2 CLCA4 VWF FRY PDLIM1 SMARCA2 FILIP1L

6.93e-0820022210b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PTPRB DST STXBP1 SYNE2 ADGRL3 DOC2B VWF SH2D3C RNF213 MACF1

6.93e-082002221072ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 HOMER1 ADGRL3 OXR1 SYNE1 OCA2 SYT10 DNAH17 DNAH11

2.75e-071772229da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IRX5 ABCA13 HOMER1 ADGRL3 OXR1 SYNE1 IRX3 FRY DNAH11

3.64e-071832229cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 TMEM163 DMD AP1M2 IRX3 IRX1 FRY MYH14

3.64e-071832229c5b10571599dc26476170b54b53f09c23e6b3117
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRX5 ADGRV1 TMEM163 C3 DEPTOR IRX3 IRX1 CCDC39 MYH14

3.81e-07184222951e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 TMEM163 AP1M2 IRX3 IRX1 FRY MYH14 TEKT4

3.81e-071842229fa4915b0498f3069fd5ef497286445528f75187e
ToppCellControl-Epithelial_alveolar-AT_2-AT2_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRX5 TMEM163 C3 DEPTOR AP1M2 IRX3 IRX1 CCDC39 MYH14

3.99e-0718522298ca1374501eca01d8468130b74d50abfd4329fbe
ToppCell3'_v3-blood-Hematopoietic_progenitors-Progenitor_Erythro-Mega|blood / Manually curated celltypes from each tissue

SPTA1 SPTBN2 OIP5 ACSM3 NYNRIN DPP10 ANK1 TFR2 PDLIM1

4.18e-07186222959c115bbbb4bca4ad80be1809d8a0422b8438ea3
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 ACSM3 TMEM163 DMD AP1M2 IRX3 IRX1 FRY

5.00e-071902229c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 TMEM163 DMD AP1M2 IRX3 IRX1 FRY MYH14

5.22e-07191222972dbd2e0fabfca8d6f604df35277d3574739a0b3
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 TMEM163 DMD AP1M2 IRX3 IRX1 FRY MYH14

5.95e-071942229c5ef4ff73b4e51530656002e3a2fb7264cdf533d
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 DMD FAM149A IRX3 IRX1 DNAH7 FRY MYH14

5.95e-071942229f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 IFT172 CFAP45 SYNE1 DNAH2 DNAH7 CCDC39 TBC1D8 DNAH11

6.76e-07197222991637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 IFT172 CFAP45 SYNE1 DNAH2 DNAH7 CCDC39 TBC1D8 DNAH11

6.76e-07197222922c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 IFT172 CFAP45 SYNE1 DNAH2 DNAH7 CCDC39 TBC1D8 DNAH11

6.76e-0719722293bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

SPTB PEX13 NLGN3 CLCN5 NOS1 TBC1D3L ITSN1 TBC1D8 PIEZO2

6.76e-0719722298545baf923ddf84c5ce9414a36d810603be52401
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 IFT172 CFAP45 SYNE1 DNAH2 DNAH7 CCDC39 TBC1D8 DNAH11

6.76e-07197222987db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellCOVID-19-Epithelial|COVID-19 / Condition, Lineage and Cell class

ABCA13 CFAP45 TUSC3 DNAH2 AP1M2 IRX3 DNAH7 MYH14 DNAH11

6.76e-07197222918fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

STXBP1 HOMER1 RASAL2 SLF1 OXR1 SYNE1 TUSC3 NBEA FRY

7.05e-0719822294ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 MYH14 DNAH11

7.36e-0719922291df69c0cb5f759f6a2152521842506a75bb95cae
ToppCellMild-Epithelial-Epithelial-|Mild / Condition, Lineage, Cell class and cell subclass

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 MYH14 DNAH11

7.36e-07199222981115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 MYH14 DNAH11

7.36e-07199222974087b4b5e567310fc4ac58fb267ff651a180680
ToppCellMild-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 MYH14 DNAH11

7.36e-071992229ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 MYH14 DNAH11

7.36e-0719922291ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 MYH14 DNAH11

7.36e-07199222900b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCellMild-Epithelial-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 MYH14 DNAH11

7.36e-07199222991308b255783ad4029e5575028c18d7550832c51
ToppCellMild_COVID-19-Epithelial|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 MYH14 DNAH11

7.36e-07199222972689bda7476930887ae007682fcab27f956f050
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

PTPRB DST STXBP1 SYNE2 DOC2B VWF SLF1 SH2D3C MACF1

7.67e-0720022294bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

OLFML2A PTPRB DST SYNE2 DOC2B VWF SH2B2 FRY FILIP1L

7.67e-0720022297eb366b2c5394af7c77650bde6261e7dac67154e
ToppCellLPS_only-Endothelial-Endothelial-Activated_Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

STXBP1 DOC2B VWF SLF1 SH2D3C RNF213 SH2B2 PDLIM1 FILIP1L

7.67e-0720022296f531a418ff25b59a543800cf4bce7b72404ce08
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

PTPRB DST STXBP1 SYNE2 DOC2B VWF SLF1 SH2D3C MACF1

7.67e-07200222981e76508c9050d533853d5fd2f3097b27613d836
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PTPRB DST STXBP1 SYNE2 ADGRL3 DOC2B VWF SLF1 MACF1

7.67e-072002229a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellCOVID-19-Myeloid-MoAM4|COVID-19 / Condition, Lineage and Cell class

F13A1 RYR1 DST NYNRIN C3 CAPN11 PDLIM1 FILIP1L

3.08e-061772228ca5d0c3d5c700bbe4c2da068eb02be6229afb9a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 FAT1 ADAMTS16 TMEM163 OXR1 IRX3 SYT10 DNAH11

3.79e-0618222285e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellControl-Epithelial_alveolar-AT_2-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRX5 TMEM163 C3 DEPTOR IRX3 IRX1 CCDC39 MYH14

3.79e-061822228e97681a4102f3095d5d9e90ad70f1dc46e90983a
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

PSMB8 CEP350 DST ERAP2 SYNE2 PARP9 RNF213 BAZ1A

3.95e-0618322288f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IRX5 ABCA13 FAT1 ADGRL3 DEPTOR OXR1 IRX3 DNAH17

3.95e-06183222892fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP|bone_marrow / Manually curated celltypes from each tissue

PRTG SPTA1 DPP10 ANK1 DEPTOR TFR2 PIEZO2 PDLIM1

4.11e-061842228b81a2a95944cee8fec13d63dc0d95496e67aa937
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IRX5 ABCA13 ADGRL3 DEPTOR OXR1 IRX3 DNAH7 DNAH11

4.11e-061842228da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IRX5 ABCA13 FAT1 ADAMTS16 ADGRL3 OXR1 IRX3 DNAH11

4.45e-0618622285c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPTA1 FNDC5 MDN1 OSBPL5 TMEM163 C3 ADGRL3

5.00e-06134222764979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 DMD FAM149A IRX3 IRX1 FRY MYH14

5.01e-0618922287659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IRX5 ABCA13 FAT1 SYNE2 OXR1 SYNE1 IRX3 DNAH11

5.21e-061902228b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYCBP2 HNRNPU PTPRB DST ADGRL3 SMARCA2 MACF1 FILIP1L

5.21e-061902228d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 DNAH11

5.41e-06191222846c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 DMD FAM149A IRX3 DNAH7 FRY MYH14

5.41e-06191222860ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellMild_COVID-19-Epithelial-Ciliated|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 DNAH11

5.41e-061912228995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 DNAH11

5.41e-061912228a37f20172b85566b9039254a89680e37fd503fd5
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 DNAH11

5.41e-0619122282a8e6d560907e71e9f6e190ca0667da804e25641
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 DMD FAM149A AP1M2 IRX3 IRX1 MYH14

5.41e-06191222805731ece7867659c662f952812805f947032fe10
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA13 CFAP45 TUSC3 DNAH2 IRX3 DNAH7 CCDC39 DNAH11

5.41e-0619122282d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

SPTA1 SPTBN2 ACSM3 DPP10 ANK1 DEPTOR TFR2 PDLIM1

5.62e-061922228cbc304c704e8524eee24a1619d0fbb2cf96c4976
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 DMD FAM149A AP1M2 IRX3 FRY MYH14

5.62e-061922228c15841f35e24d6ef6ce2a9a6dc62e66efdc3d9d5
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 DMD FAM149A IRX1 DNAH7 TBC1D8 FRY

5.62e-061922228b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCA13 ADGRV1 DNAH2 IRX3 DNAH7 CCDC39 TBC1D8 DNAH11

5.84e-061932228ea345d34440b25f65358a53dc72831998d1c3620
ToppCellPCW_05-06-Epithelial-Epithelial_airway|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 DMD AP1M2 IRX3 IRX1 FRY MYH14

5.84e-061932228af6ec2c2ba92aef3e41531c3c7215b3300437bd9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN8 SYNE2 DEPTOR OXR1 SYNE1 DNAH7 TBC1D8 MYH14

5.84e-06193222842df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN8 SYNE2 DEPTOR OXR1 SYNE1 DNAH7 TBC1D8 MYH14

5.84e-061932228f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 PTPRB RASAL2 SYNE1 SH2D3C TBC1D8 PIEZO2 IRAK3

5.84e-061932228456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 SYNE2 DEPTOR OXR1 SYNE1 RNF213 DNAH7 MYH14

6.07e-061942228e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellPCW_05-06-Epithelial|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 TMEM163 AP1M2 IRX3 IRX1 FRY MYH14

6.07e-06194222847a1369c22fcbfe00b08376eb610a61c355548db
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRB DST STXBP1 ADGRL3 RASAL2 VWF SLF1 MACF1

6.07e-0619422280b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 ADGRV1 DMD AP1M2 IRX3 IRX1 FRY MYH14

6.07e-061942228b19e16a76d7342ff9a665d19c9151652916f17d4
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRV1 CAPN8 FAT1 SYNE2 FAM149A DPP10 NBEA MYH14

6.30e-061952228dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 DST STXBP1 TMEM163 NBEA GRIN2C MADD MACF1

6.30e-0619522283e519cffa6144a62b06124642a14c9ff39b76554
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|kidney / Disease (COVID-19 only), tissue and cell type

GALNT15 PTPRB DOC2B VWF SH2D3C IRX3 CARD8 IRAK3

6.54e-061962228ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE2 OSBPL5 NCR1 USP28 SYNE1 RNF213 ARHGAP9 MACF1

7.04e-0619822280e918e9db9b884f5328d438e90efe065e27266ee
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE2 OSBPL5 NCR1 USP28 SYNE1 RNF213 ARHGAP9 MACF1

7.04e-061982228ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE2 OSBPL5 NCR1 USP28 SYNE1 RNF213 ARHGAP9 MACF1

7.04e-061982228fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNE2 OSBPL5 NCR1 USP28 SYNE1 RNF213 ARHGAP9 MACF1

7.04e-0619822281ef3a6bd681c223eed58300348adfef89df5563c
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FAT1 ACSM3 DST DMD SYNE1 ITSN1 SYT10 FILIP1L

7.31e-061992228e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

IRX5 ADGRV1 FAT1 AP1G2 C3 IRX3 IRX1 CCDC39

7.58e-062002228e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

STXBP1 DOC2B VWF RNF213 SH2B2 PDLIM1 MACF1 FILIP1L

7.58e-0620022282d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

STXBP1 SYNE2 DOC2B SLF1 SH2D3C RNF213 SH2B2 MACF1

7.58e-062002228edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

MYCBP2 STXBP1 RASAL2 SLF1 OXR1 SYNE1 NBEA FRY

7.58e-06200222848d801219bc771d6c7e151dc88ca4c179988de85
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MYCBP2 HNRNPU CEP350 SYNE2 PARP9 RNF213 MACF1 AKAP13

7.58e-06200222812f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

FAT1 ACSM3 DST DMD SYNE1 ITSN1 SYT10 FILIP1L

7.58e-062002228593bf6a7c557437db9a9249a5058a46014179ef6
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / Treatment groups by lineage, cell group, cell type

PTPRB SYNE2 CFAP45 DOC2B VWF SH2B2 PDLIM1 FILIP1L

7.58e-062002228b036f5e22c95a3b14391785b6e91aa183b9bc9a8
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FAT1 ACSM3 DST DMD SYNE1 ITSN1 SYT10 FILIP1L

7.58e-062002228c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-NK_activated|COVID-19_Severe / Disease, condition lineage and cell class

SYNE2 OSBPL5 NCR1 USP28 SYNE1 RNF213 ARHGAP9 MACF1

7.58e-0620022286a77f9643646bafc1157bf1fc1e4c614860ee642
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

SYNE2 PARP9 NCR1 USP28 SYNE1 USP24 RNF213 MACF1

7.58e-0620022282281debd86e5d92e8fe0397aec9ef670800f7471
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF5 OSBPL5 TMEM163 NCR1 SH2D3C TASP1 SRRT

1.87e-051642227950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF5 OSBPL5 TMEM163 NCR1 SH2D3C TASP1 SRRT

1.87e-051642227c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCelldroplet-Liver-nan-3m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF5 OSBPL5 TMEM163 NCR1 SH2D3C TASP1 SRRT

1.87e-051642227bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT1-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRX5 TMEM163 AP1M2 IRX3 IRX1 MYH14

2.09e-051122226456278fb92dd41820fde8cf27c68fec45e15f972
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

FAT1 SYNE2 ADAMTS16 TMEM163 MYRF OXR1 DNAH7

2.18e-051682227a086c306be430adf0632ba53e98cd8014d2de330
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA13 KDM5C CEP350 TRAF7 POMT1 DNAH7 KLHDC10

2.36e-0517022270f215911b5880eeffeb43230f7eeaf55b612eaf2
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTGFRN F13A1 FAM162B DPP10 OCA2 LRRK1 ABCC12

2.45e-0517122279e00c8191ca9d52151a49baf39f8581cb176fb76
ToppCellfacs-GAT-Fat-24m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 IRX4 KIAA0753 CKMT1A CLCA4 AP1M2 MYH14

2.64e-05173222798e464d9e6d6b69421e9e4041b638b6825247f60
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

HNRNPU FAT1 DST SYNE1 RNF213 MACF1

1.57e-05501176GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Drugplakin

SPTA1 SPTB SPTBN2 ACTL7B DST SYNE2 DMD SYNE1 MACF1

6.39e-08822099CID000018752
Diseaseprimary ovarian insufficiency (implicated_via_orthology)

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

1.73e-194621714DOID:5426 (implicated_via_orthology)
Diseasecongenital heart disease (implicated_via_orthology)

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

9.60e-176921714DOID:1682 (implicated_via_orthology)
Diseasehereditary spherocytosis (is_implicated_in)

SPTA1 SPTB ANK1

3.88e-0652173DOID:12971 (is_implicated_in)
DiseaseHereditary spherocytosis

SPTA1 SPTB ANK1

3.88e-0652173cv:C0037889
DiseaseAnemia, hereditary spherocytic hemolytic

SPTA1 SPTB ANK1

3.88e-0652173C0221409
DiseaseHereditary spherocytosis

SPTA1 SPTB ANK1

2.14e-0582173C0037889
DiseasePR interval

PCNX3 MYCBP2 ZNF184 FAT1 SYNE2 CAMTA1 ADGRL3 USP28 SUN1 MACF1 NUDCD1 CDC5L DNAH11

8.45e-0549521713EFO_0004462
Diseasecryptorchidism (implicated_via_orthology)

SYNE2 ADAMTS16

1.61e-0432172DOID:11383 (implicated_via_orthology)
Diseasebreast angiosarcoma (is_implicated_in)

PTPRB PIK3CA

1.61e-0432172DOID:4511 (is_implicated_in)
DiseaseLung diseases

IRX5 IRX3 IRX1 PRKDC DNAH11

2.80e-04782175C0024115
Diseasereticulocyte measurement

SPTA1 SPTB FAT1 PIK3CA SYNE2 VWF ANK1 DEPTOR OXR1 TRIM31 ARHGAP9 TFR2 TBC1D8 UBE2O BAZ1A DNAH17 LRP5 AKAP13 ACAP2

3.11e-04105321719EFO_0010700
DiseaseHereditary elliptocytosis

SPTA1 SPTB

3.20e-0442172cv:C0013902
Diseasehereditary spherocytosis type 1 (implicated_via_orthology)

SPTA1 ANK1

3.20e-0442172DOID:0110916 (implicated_via_orthology)
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTB SPTBN2

3.20e-0442172DOID:0050882 (implicated_via_orthology)
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE2 SYNE1

3.20e-0442172cv:CN293514
DiseaseGlobal developmental delay

KDM5C SPTBN2 TRAF7 OXR1 NBEA TKFC

4.66e-041332176C0557874
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE2 SYNE1

5.31e-0452172C1450051
Diseasehereditary spastic paraplegia 76 (implicated_via_orthology)

CAPN8 CAPN11

5.31e-0452172DOID:0110821 (implicated_via_orthology)
DiseaseDuchenne muscular dystrophy (is_marker_for)

DMD NOS1

5.31e-0452172DOID:11723 (is_marker_for)
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE2 SYNE1

5.31e-0452172C0410190
DiseaseFamilial Exudative Vitreoretinopathy

RCBTB1 LRP5

5.31e-0452172C0339539
Diseasealcohol use disorder (implicated_via_orthology)

KDM5C RYR1 STXBP1 HOMER1 MADD SMARCA2 CDC5L

6.28e-041952177DOID:1574 (implicated_via_orthology)
Diseaseneutrophil percentage of leukocytes

ZCWPW2 SPTA1 NCLN MED24 ERAP2 SLC25A24 ANK1 SH2D3C TBC1D8 UBE2O AKAP13 PRKDC XKR5

6.30e-0461021713EFO_0007990
Diseasereticulocyte count

EPRS1 SPTA1 SPTB FAT1 SYNE2 MYRF VWF ANK1 OXR1 TRIM31 ARHGAP9 TFR2 TBC1D8 UBE2O BAZ1A DNAH17 LRP5 ACAP2

7.67e-04104521718EFO_0007986
DiseaseEmery-Dreifuss muscular dystrophy

SYNE2 SYNE1

7.92e-0462172cv:C0410189
Diseaseprocollagen C-endopeptidase enhancer 1 measurement

TFR2 DNAH11

7.92e-0462172EFO_0801920
DiseaseElliptocytosis, Hereditary

SPTA1 SPTB

7.92e-0462172C0013902
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE2 SYNE1

7.92e-0462172C0410189
Diseasered blood cell density measurement

WWOX SPTA1 ADGRV1 DST UBR5 PIK3CA CAMTA1 HSF2 MYRF ANK1 ITSN1 DNAH2 IRX1 TFR2 BAZ1A AKAP13

8.58e-0488021716EFO_0007978
DiseaseAdenoid Cystic Carcinoma

IRX4 FAT1 PIK3CA SMARCA2 PRKDC

8.78e-041002175C0010606
Diseaserevision of total knee arthroplasty

WWOX ADGRL3 XKR5

9.00e-04262173EFO_0020972
DiseaseCerebellar Diseases

NOS1 CASK

1.10e-0372172C0007760
Diseaseosteopetrosis (implicated_via_orthology)

CLCN5 LRRK1

1.10e-0372172DOID:13533 (implicated_via_orthology)
Diseaseatrioventricular septal defect (implicated_via_orthology)

IFT172 DNAH11

1.10e-0372172DOID:0050651 (implicated_via_orthology)
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE2 SYNE1

1.10e-0372172C0751337
DiseasePARTINGTON X-LINKED MENTAL RETARDATION SYNDROME

KDM5C CASK

1.46e-0382172C0796250
Diseasemanic episode measurement, depressive episode measurement

NFYC DEPTOR

1.87e-0392172EFO_0007704, EFO_0007705
Diseaseintellectual disability (implicated_via_orthology)

KDM5C CAPN8 ITSN1 CAPN11

2.30e-03752174DOID:1059 (implicated_via_orthology)
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CAPN8 DMD CAPN11

2.34e-03362173DOID:11723 (implicated_via_orthology)
DiseasePrimary ciliary dyskinesia

DNAAF5 CCDC39 DNAH11

2.34e-03362173cv:C0008780
DiseaseDevelopmental delay (disorder)

KDM5C SPTBN2 TKFC

2.53e-03372173C0424605
DiseaseMalignant neoplasm of breast

WWOX LRRC37A2 PKDREJ SYNJ2 PIK3CA SYNE2 NFYC AP1M1 DMD RASAL2 VWF ANK1 SYNE1 OCA2 MACF1 TEKT4 KLHDC10

2.61e-03107421717C0006142
DiseaseSarcomatoid Renal Cell Carcinoma

KDM5C RYR1 PIK3CA SYNE2 AKAP13

2.61e-031282175C1266043
DiseaseChromophobe Renal Cell Carcinoma

KDM5C RYR1 PIK3CA SYNE2 AKAP13

2.61e-031282175C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

KDM5C RYR1 PIK3CA SYNE2 AKAP13

2.61e-031282175C1266044
DiseasePapillary Renal Cell Carcinoma

KDM5C RYR1 PIK3CA SYNE2 AKAP13

2.61e-031282175C1306837
DiseaseRenal Cell Carcinoma

KDM5C RYR1 PIK3CA SYNE2 AKAP13

2.61e-031282175C0007134
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPG RNF213

2.83e-03112172DOID:0060669 (implicated_via_orthology)
Diseaseguanosine diphosphate measurement

NBEA NINL

2.83e-03112172EFO_0010494
Diseasegastric adenocarcinoma (is_implicated_in)

ABCA13 UBR5

2.83e-03112172DOID:3717 (is_implicated_in)
DiseaseIschemic stroke

GALNT15 ILF3 NYNRIN PRMT9 ADGRL3 USP28 CDC5L DNAH11

2.87e-033242178HP_0002140
Diseasefactor VIII measurement

VWF SCARA5 ABCC12

3.17e-03402173EFO_0004630
Diseaseperipheral arterial disease, traffic air pollution measurement

WWOX ACSM3 OXR1 ARHGAP9 NBEA MACF1

3.22e-031942176EFO_0004265, EFO_0007908
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE2 SYNE1

3.38e-03122172DOID:11726 (implicated_via_orthology)
DiseaseAbruptio Placentae

GALNT15 IRX1

3.38e-03122172EFO_1001754
DiseaseCongenital muscular dystrophy

RYR1 POMT1

3.38e-03122172cv:C0699743
Diseasevenous thromboembolism, von Willebrand factor measurement

MYRF VWF SCARA5

3.65e-03422173EFO_0004286, EFO_0004629
DiseaseFulminant Hepatic Failure with Cerebral Edema

NOS1 PRKDC

3.98e-03132172C0751197
DiseaseHepatic Stupor

NOS1 PRKDC

3.98e-03132172C0751198
DiseaseFetal Alcohol Spectrum Disorders

PIK3CA NOS1

3.98e-03132172C2985290
DiseaseHepatic Encephalopathy

NOS1 PRKDC

3.98e-03132172C0019151
DiseaseHepatic Coma

NOS1 PRKDC

3.98e-03132172C0019147
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

SYNE2 OGDH MADD MACF1 NUDC

4.33e-031442175EFO_0004611, EFO_0020943
DiseaseKartagener syndrome (implicated_via_orthology)

CCDC39 DNAH11

4.62e-03142172DOID:0050144 (implicated_via_orthology)
Diseaseearly cardiac repolarization measurement

MYCBP2 LRP5

4.62e-03142172EFO_0004885
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

KDM5C RYR1 PIK3CA SYNE2 AKAP13

4.86e-031482175C0279702
Diseaseunipolar depression, information processing speed, cognitive function measurement

GALNT15 ADCY10 ZNF350

5.01e-03472173EFO_0003761, EFO_0004363, EFO_0008354
DiseasePrimary Ciliary Dyskinesia

DNAAF5 CCDC39 DNAH11

5.01e-03472173C4551720
Diseasecleft lip

PRTG WWOX PTGFRN DST GVINP1 SYNE1 FRY

5.23e-032842177EFO_0003959
Diseaseautism spectrum disorder (implicated_via_orthology)

KDM5C NLGN3 NBEA CASK EIF4E1B

5.43e-031522175DOID:0060041 (implicated_via_orthology)
Diseaseforced expiratory volume

ILF3 WWOX SPTBN2 ZNF184 KIAA0753 DST ANK1 SYNE1 TASP1 ARHGAP12 SMARCA2 LRP5 CDC5L

5.88e-0378921713EFO_0004314
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

STXBP1 CASK

6.04e-03162172C0393706
DiseaseBenign neoplasm of stomach

UBR5 PIK3CA

6.81e-03172172C0153943
Diseaseocular hypertension (biomarker_via_orthology)

ACSM3 C3

6.81e-03172172DOID:9282 (biomarker_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of stomach

UBR5 PIK3CA

6.81e-03172172C0496905
Diseasemuscular dystrophy (is_implicated_in)

SYNE1 POMT1

6.81e-03172172DOID:9884 (is_implicated_in)
DiseaseCarcinoma in situ of stomach

UBR5 PIK3CA

6.81e-03172172C0154060
Diseaselevel of Sphingomyelin (d32:1) in blood serum

SYNE2 NUP88

6.81e-03172172OBA_2045173
DiseaseFetal Alcohol Syndrome

PIK3CA NOS1

6.81e-03172172C0015923
Diseaseinterleukin 1 receptor antagonist measurement

SH2D3C OCA2 DNAH11

7.01e-03532173EFO_0004754
Diseaseepilepsy (implicated_via_orthology)

WWOX NOS1 KCNT1 GRIN2C NUDC

7.25e-031632175DOID:1826 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
TAWAHVAVRLIKDSV

ACOX2

501

Q99424
TEWSREEEEKLLHLA

CDC5L

61

Q99459
KWRTKHADSIDLELE

CAMTA1

1086

Q9Y6Y1
RHLKAWDDNLTLDIS

ERVK13-1

401

Q9NX77
DTRKWTLVGHELLNT

ACTL7B

91

Q9Y614
EEIRLDTSSEASHWK

PRMT9

796

Q6P2P2
LIWIESVIEKFSHSR

AP1M2

276

Q9Y6Q5
WLRAEVKRLSHELAE

BICD2

21

Q8TD16
LVVLRSENGSVWKEH

ANK1

1006

P16157
HTGDTESQVRLLWKD

COMP

656

P49747
VWDIILSSHRSNFKD

GVINP1

471

Q7Z2Y8
LHISSDASRLAIIWK

A4GNT

146

Q9UNA3
VEVHASSKEERNSWI

AKAP13

2311

Q12802
SDAVHDLLLDVITWV

ADGRL3

856

Q9HAR2
RLEWTIDEKAKHNLS

ADGRV1

4071

Q8WXG9
WTSISSLKAVAREHL

APTX

221

Q7Z2E3
KRWHIDTILHVLTTA

AP1G2

416

O75843
LIWIESVIEKHSHSR

AP1M1

276

Q9BXS5
IHWESASLLRSEETK

C3

1311

P01024
RWETTKKIAATVRHE

DNAH11

1221

Q96DT5
VQLISEDWSLEKSTH

ABCA13

2006

Q86UQ4
DSLSSEEVHKWNLVL

CAPN8

346

A6NHC0
VSEHRKDLGLTTVWE

CEP76

536

Q8TAP6
LDWVSKEDGSHILTV

DMXL2

1171

Q8TDJ6
ILREHIAKAEAEVWA

C6orf163

66

Q5TEZ5
LSSGETEELQRIKWH

CYTH4

11

Q9UIA0
RKRLDVDITELHSWI

DMD

721

P11532
VDITELHSWITRSEA

DMD

726

P11532
IRSHLEASSDQWKRL

DMD

2796

P11532
TEIKEQRHWDISSSE

DUS3L

531

Q96G46
VHFSKVRSLTLDTWE

ACAP2

446

Q15057
RLWELSVTQEHIFSK

ADCY10

1361

Q96PN6
LRVFTEKHSESWELD

CAPN11

536

Q9UMQ6
QEETWRLSFSHIEKE

CGAS

371

Q8N884
VTDKFHIDWDSVLID

DPP10

576

Q8N608
ASEVLVTSRTWELAH

ADAMTS16

216

Q8TE57
LHLSTLDRSVIWSKS

BAZ1A

1131

Q9NRL2
WLEESAHKDSDALTL

CCDC39

146

Q9UFE4
VSWRLLSVEHEDFLT

RCBTB1

341

Q8NDN9
LTHVVEWIDFETLAL

OCA2

376

Q04671
NETEILIWKSHVSGE

RBM41

91

Q96IZ5
RETTSTLKAWLQEHR

IRX4

151

P78413
TRDATATLKAWLNEH

IRX5

121

P78411
PRIELSVWKDDLTTH

PARP9

116

Q8IXQ6
SVWKDDLTTHAVDAV

PARP9

121

Q8IXQ6
DVLVKGDSRWVTTLH

CDC42BPG

121

Q6DT37
KRWLEDNLDHTDSSL

NCLN

286

Q969V3
HESSTWIIKESNSLE

NUDCD1

331

Q96RS6
WVKVESTDVSDLLHQ

PSMB8

256

P28062
SEIQISHSWEEGLKL

PABIR3

101

Q6P4D5
HSVWTLRRVKSEEEN

ANAPC1

266

Q9H1A4
TGWITTLKELDHEKR

FAT1

2866

Q14517
QWSHISESAKDLVRR

CASK

241

O14936
KESRVLAPWITETHF

PTPRB

331

P23467
LKVDTSESLWHIQIS

KIAA0100

146

Q14667
RWKDLTHAISILESA

LRRC37A3

1271

O60309
LLEKHVSSLRAHETW

MDN1

2411

Q9NU22
KSSALLHDLREIEAW

MADD

236

Q8WXG6
RWKDLTHAISILESA

LRRC37A2

1271

A6NM11
LTTETGLQKDHALWD

NCR1

236

O76036
VELLEELIRKHWETT

FAM149A

466

A5PLN7
ELIRKHWETTLTEGK

FAM149A

471

A5PLN7
AWSRKHKTLSIDQDE

LIPM

136

Q5VYY2
VVHGEATIRTTKWEL

LRRK1

666

Q38SD2
DSITTIKHWITIIRA

DST

6996

Q03001
HLVTKVDTVEDFWAL

EIF4E1B

86

A6NMX2
TDWNLHSIERADKTS

LRP5

861

O75197
TAADHQTILRAWAVK

KCNT1

446

Q5JUK3
DEAWSTLLRTVHSIL

GALNT15

201

Q8N3T1
RIKWASHVLTREELE

CFAP45

111

Q9UL16
LATSEATWKDTEHSR

C9orf131

536

Q5VYM1
LHQSTDRLTAEIWKD

MYH14

626

Q7Z406
KLEVWLSHEGITAAL

PCNX3

1501

Q9H6A9
STDLHKLDLNTREWT

KLHDC10

231

Q6PID8
TKDIDIHEVRIGWSL

HNRNPU

351

Q00839
LRTSHWEEAIQETKG

NANP

71

Q8TBE9
RELSVLHSLLWEVVS

RASAL2

571

Q9UJF2
LNVTSVHLFKERWDT

F13A1

46

P00488
ELWTRSHRDDSEKLL

LRIT3

641

Q3SXY7
ERLSSSWLDVRHIEK

IRAK3

46

Q9Y616
SSAISKHWEAELATL

HOMER1

176

Q86YM7
FITELTLRAWIHTED

NFYC

76

Q13952
SEITEQEKDFLWSHR

PIK3CA

541

P42336
SLHKFVSRATAELIW

MACF1

681

Q9UPN3
VLTKWRHSTIVLDTN

ARHGAP12

416

Q8IWW6
SRVDWLELNETGHKL

IFT172

486

Q9UG01
WETEVVLTDTLHLKS

NOS1

311

P29475
ISWSRLDHKSIDVFN

PRTG

266

Q2VWP7
DVWKTILSEVRFVHV

POMT1

456

Q9Y6A1
SQTEAEELRKLWKTH

OXR1

496

Q8N573
RKTLVALFTDHQWVE

NLGN3

471

Q9NZ94
AEWRSTFHKDVVVDL

OGDH

491

Q02218
SLHVDITRWHESIKE

DPYSL4

136

O14531
ITRWHESIKEELEAL

DPYSL4

141

O14531
SKEEKEDWLSHALSR

FBF1

416

Q8TES7
KDKRIERWHTLTSEL

DOC2B

391

Q14184
WVLLSRHITDKDDFA

CAPN7

586

Q9Y6W3
WLSVEDILAVRAVHS

CCNF

46

P41002
TIIDWSHQIRDVLSK

DNAH17

196

Q9UFH2
NVASLRHELKITEWS

CCDC18

21

Q5T9S5
RHELKITEWSLQSLG

CCDC18

26

Q5T9S5
EWSVTKRQVILLHTE

DCAKD

181

Q8WVC6
EKTETSHEQWLFKRL

FILIP1L

691

Q4L180
EAWSTLLRTIHSVLE

GALNT4

146

Q8N4A0
SLDIWAITVEERAKH

ITSN1

11

Q15811
KEWVSALIHSELAEI

C4orf17

211

Q53FE4
DRHREITNKSKESTW

CLCN5

101

P51795
DWLIEHKEASDRETA

DEPTOR

71

Q8TB45
ETTETTEVIKRLWVH

DNAH7

2196

Q8WXX0
EKTRWSHTALELGQL

DNAH7

2886

Q8WXX0
SHTERALKAVSDWID

ILF3

36

Q12906
LEITEKRHGTLVWDT

CARD8

416

Q9Y2G2
WDALSQTKAALRHIE

CEP350

31

Q5VT06
SELTLSQKHWLSDRT

IGHE

176

P01854
SSASDKLWVTRVIAH

ERAP2

356

Q6P179
DLSKIEIHRVWTSAS

FRY

2306

Q5TBA9
HDITDWVVGTRVKSA

DNAAF5

366

Q86Y56
KDFHDTKSSITRLWI

DNAH2

2631

Q9P225
DWEHSIALRNISLAK

SCARA5

291

Q6ZMJ2
VTSEEELHLTRKLFW

RYR1

2666

P21817
KSFLIWVNEEDHTRV

CKMT1A

256

P12532
AVERHESLTSWNLAK

FAM162B

131

Q5T6X4
LREISLNHEWTFEKL

LRRC8D

446

Q7L1W4
GDLSVHRETTWKTRL

OLFML2A

556

Q68BL7
ELLELHWRVADKASE

NYNRIN

1796

Q9P2P1
NLTLTVARSEHKVWS

PDLIM1

76

O00151
KDTLSWLAVDNVAHT

MR1

146

Q95460
LSKLWTLVEETHTNE

HSF2

11

Q03933
RESTSTLKAWLNEHR

IRX3

136

P78415
DKTFLIWINEEDHTR

CKMT2

256

P17540
ESERLWQHVTRAISK

OSBPL5

646

Q9H0X9
DHTSEKSWDSRIDLI

NUP88

346

Q99567
VLADSVHLAWDLSRS

OIP5

86

O43482
IIKHSDDEVSATASW

KIF13A

1216

Q9H1H9
DWKSDLSLERVSVLE

PTGFRN

761

Q9P2B2
SERLLDLHQSWKTKD

PGGT1B

351

P53609
SEELHAALSEWLTAI

TRIM31

401

Q9BZY9
TEIDHWLEFSATKLS

EPRS1

76

P07814
VEHLIEKWELQRSLS

TDRD3

61

Q9H7E2
LSKAVATWHANTERE

SMARCA2

476

P51531
IEAELRSTKHWELTA

FARSA

51

Q9Y285
RSTKHWELTAEGEEI

FARSA

56

Q9Y285
NRLEVTWDDTKRLIH

SYNE1

2061

Q8NF91
SLRTWLAHIESELAK

SYNE1

7896

Q8NF91
SRESVELLLEDWHKF

SYNE2

511

Q8WXH0
TLGHWVTISDQEKRT

SYNJ2

1471

O15056
KWTVDDVHSFIRSLP

SAMD7

326

Q7Z3H4
RESTSTLKAWLNEHR

IRX1

136

P78414
KWLSVDTTLDRTFHV

PKDREJ

1331

Q9NTG1
TVRHLKANSAVVSWD

FNDC5

41

Q8NAU1
RVWVDTLSIAHSKVT

NBEA

936

Q8NFP9
LSIDSVEDHLAWSKD

PRDX6

71

P30041
AKLEEASSWTAIEHS

MED24

181

O75448
VGERLQDTHSWKSEL

TEKT4

91

Q8WW24
IKQVDLDSRHIGWVT

MYCBP2

3826

O75592
ATRVREEWEHAISSK

MYCBP2

3981

O75592
HLSEAWSRVTKNAIA

MYCBP2

4186

O75592
WKLLSTHSDEVTDSI

PEX13

251

Q92968
HEAARLAWLDAETSK

KIAA0753

606

Q2KHM9
AVAAEKWSHLSLTRR

PGBD1

226

Q96JS3
TWARDEDTVLKHLRA

TBC1D3L

331

B9A6J9
LKSHLWRSASLESVE

NINL

136

Q9Y2I6
DLWIALRHKHIAEVS

STXBP1

286

P61764
LANATLTWEHEASRK

ABCC12

436

Q96J65
SSWLIEDGKVVTVHL

NUDC

231

Q9Y266
SLKWETERARQVLEH

SNF8

201

Q96H20
KLIHTLDDRTQLWAS

SRRT

526

Q9BXP5
LQSWKHLEDGARTET

APOL5

311

Q9BWW9
LHSKLIVSENSREGW

ACSM3

191

Q53FZ2
LDATVHEDKIILTWT

CLCA4

761

Q14CN2
TWARDEDTVLKHLRA

TBC1D3B

331

A6NDS4
TWARDEDTVLKHLRA

TBC1D3H

331

P0C7X1
LEWLKTVNESHGSVE

RNF213

1516

Q63HN8
ERATQESTLDHWKFL

USP17L3

426

A6NCW0
EQLAKWIADRTDVHI

TUSC3

176

Q13454
SVVWDRHLSISVVLK

VWF

971

P04275
VVSVSRDGTLKVWDH

TEP1

2161

Q99973
LHRRWDELETTTQAK

SPTBN2

1361

O15020
SKNLLSSWDEVIHIA

TBCE

161

Q15813
TWARDEDTVLKHLRA

TBC1D3F

331

A6NER0
WTLVDVRRDLHKTTI

WDR97

281

A6NE52
HSIALWAVSDKGDVL

TECPR1

951

Q7Z6L1
AAERDWTVSLEHILA

TBC1D8

1076

O95759
ERATQESTLDHWKFL

USP17L18

426

D6R9N7
ETSDLRNKWHLVIDR

PIEZO2

901

Q9H5I5
RIESWLETHALLEKA

UBE2O

1141

Q9C0C9
ERATQESTLDHWKFL

USP17L5

426

A8MUK1
IHVWDIESKEQVRTL

TRAF7

581

Q6Q0C0
ERATQESTLDHWKFL

USP17L21

426

D6R901
ASEAVSRILEEWHKA

WWOX

161

Q9NZC7
ERATQESTLDHWKFL

USP17L19

426

D6RCP7
STEWDDIHVVTGALK

ARHGAP9

621

Q9BRR9
LETIDSLQKHSWVAD

SH2B2

286

O14492
TWARDEDTVLKHLRA

TBC1D3E

331

A0A087X179
ALHRLWDELQATTKE

SPTB

1356

P11277
EDLVSSWEHIRALAT

SPTA1

346

P02549
VLERTWKHLSDIIEE

SPTA1

2126

P02549
ERATQESTLDHWKFL

USP17L1

426

Q7RTZ2
VSEFTHKLLDWLEDA

USP28

256

Q96RU2
VSDLSREATVWKDIH

SYT10

341

Q6XYQ8
HKETTSVHTDWLLDL

SLF1

996

Q9BQI6
WSESSEHLQLVVTDK

VSTM1

106

Q6UX27
ELHKESKTRDDWLVS

PRKDC

3261

P78527
LASSKTHEITQLESW

ZNF773

56

Q6PK81
IWKVDHVLERLQSES

ZNF350

81

Q9GZX5
ERATQESTLDHWKFL

USP17L12

426

C9JPN9
HLFVLIQKSWETESD

USP24

511

Q9UPU5
TTSGKVLDVLWELAH

USP24

546

Q9UPU5
ERATQESTLDHWKFL

USP17L24

426

Q0WX57
ETSNSEDRLLKHWVS

ZNF594

36

Q96JF6
EELKLSSTDLRSHAW

SH2D3C

206

Q8N5H7
TWTELLKHVRETHKE

GTF3A

201

Q92664
TWARDEDTVLKHLRA

TBC1D3D

331

A0A087WVF3
ELDQLKSELSSWRHV

SUN1

481

O94901
WRLLSSEDSAKVDHD

ZCWPW2

41

Q504Y3
VSSSHDKSLRLWERT

WDR3

691

Q9UNX4
RHWDAALTSLQKELE

XKR5

81

Q6UX68
TTHSRAARAIQEWLK

TKFC

406

Q3LXA3
ERATQESTLDHWKFL

USP17L22

426

D6RA61
TWARDEDTVLKHLRA

TBC1D3G

331

Q6DHY5
TWARDEDTVLKHLRA

TBC1D3

331

Q8IZP1
ERATQESTLDHWKFL

USP17L15

426

C9J2P7
ERATQESTLDHWKFL

USP17L17

426

D6RBQ6
ILLSAEVFKHDSAVW

TMEM163

236

Q8TC26
KQTLLVEFLWSHTTE

TASP1

361

Q9H6P5
AALSRQKLDHVWTDT

TFR2

181

Q9UP52
VTDIEEIIRFWKHST

SLC25A24

156

Q6NUK1
TWARDEDTVLKHLRA

TBC1D3K

331

A0A087X1G2
EAERKLLTWESVHKE

TRPM4

1116

Q8TD43
ESLISAHDILSWIKQ

ZNF282

356

Q9UDV7
SHTSIWLLRTDFVLE

UGT1A7

246

Q9HAW7
EVTSKLFDEIHWIIV

TTLL1

276

O95922
TWARDEDTVLKHLRA

TBC1D3I

331

A0A087WXS9
TWARDEDTVLKHLRA

TBC1D3C

331

Q6IPX1
ERATQESTLDHWKFL

USP17L20

426

D6RJB6
IVEKHKRDDSWSSNL

ZNF184

126

Q99676
IAREWSEKAAHLLAL

ZFTA

476

C9JLR9
WVDETLSSVASKLEH

UBR5

446

O95071
ERATQESTLDHWKFL

USP17L10

426

C9JJH3
ERATQESTLDHWKFL

USP17L11

426

C9JVI0
SSHLEQREALWIEEK

ZNF554

126

Q86TJ5
LELQVLTAHSWREKA

KDM5C

1071

P41229
NLETRIDELERWSHK

MYRF

691

Q9Y2G1
ADASHVSWRLLDVVT

GRIN2C

186

Q14957