Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP:ADP antiporter activity

SLC25A4 SLC25A5 SLC25A6

7.94e-075873GO:0005471
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

8.16e-0740875GO:0140662
GeneOntologyMolecularFunctionATP-dependent protein disaggregase activity

HSPA1A HSPA1B HSPA8

1.58e-066873GO:0140545
GeneOntologyMolecularFunctionC3HC4-type RING finger domain binding

HSPA1A HSPA1B HSPA8

1.58e-066873GO:0055131
GeneOntologyMolecularFunctionADP transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

1.29e-0511873GO:0015217
GeneOntologyMolecularFunctionprotein folding chaperone

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

1.66e-0573875GO:0044183
GeneOntologyMolecularFunctionATP transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

2.81e-0514873GO:0005347
GeneOntologyMolecularFunctionprotein-containing complex destabilizing activity

HSPA1A HSPA1B HSPA8

3.50e-0515873GO:0140776
GeneOntologyMolecularFunctiondenatured protein binding

HSPA1A HSPA1B

5.61e-053872GO:0031249
GeneOntologyMolecularFunctionheat shock protein binding

SACS HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

7.89e-05163876GO:0031072
GeneOntologyMolecularFunctionpurine ribonucleotide transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

1.33e-0423873GO:0005346
GeneOntologyMolecularFunctionadenine transmembrane transporter activity

SLC25A4 SLC25A5

1.86e-045872GO:0015207
GeneOntologyMolecularFunctiondeath receptor agonist activity

HSPA1A HSPA1B

1.86e-045872GO:0038177
GeneOntologyMolecularFunctionoxidative phosphorylation uncoupler activity

SLC25A4 SLC25A5

1.86e-045872GO:0017077
GeneOntologyMolecularFunctionadenine nucleotide transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

1.93e-0426873GO:0000295
GeneOntologyMolecularFunctionpurine nucleotide transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

2.69e-0429873GO:0015216
GeneOntologyMolecularFunctionnucleotide transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

3.97e-0433873GO:0015215
GeneOntologyMolecularFunctiondisordered domain specific binding

HSPA1A HSPA1B HSPA2

6.52e-0439873GO:0097718
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

6.52e-0439873GO:0015605
GeneOntologyMolecularFunctionATP hydrolysis activity

ERCC6 CHD3 DDX24 HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

6.76e-04441878GO:0016887
GeneOntologyMolecularFunctionpurine nucleobase transmembrane transporter activity

SLC25A4 SLC25A5

8.26e-0410872GO:0005345
GeneOntologyMolecularFunctionnucleobase transmembrane transporter activity

SLC25A4 SLC25A5

1.01e-0311872GO:0015205
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

2.18e-0359873GO:1901505
GeneOntologyMolecularFunctionnucleobase-containing compound transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

2.18e-0359873GO:0015932
GeneOntologyMolecularFunctionunfolded protein binding

HSPA1A HSPA1B HSPA2 HSPA8

2.25e-03126874GO:0051082
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

PPP1R3C TPTE ARSL PTPRJ RNASE8 POLE MGLL PNPLA8 SSH2 REXO1L1P

2.65e-038078710GO:0016788
GeneOntologyMolecularFunctionmisfolded protein binding

HSPA1A HSPA1B

2.74e-0318872GO:0051787
GeneOntologyMolecularFunctionpyrophosphatase activity

ARL5C ERCC6 CHD3 PPA1 DDX24 HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

3.49e-038398710GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ARL5C ERCC6 CHD3 PPA1 DDX24 HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

3.52e-038408710GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ARL5C ERCC6 CHD3 PPA1 DDX24 HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

3.52e-038408710GO:0016818
GeneOntologyMolecularFunctiondeath receptor activity

HSPA1A HSPA1B

3.73e-0321872GO:0005035
GeneOntologyBiologicalProcessnegative regulation of inclusion body assembly

SACS HSPA1A HSPA1B HSPA2

1.30e-0712854GO:0090084
GeneOntologyBiologicalProcessprotein refolding

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

1.39e-0730855GO:0042026
GeneOntologyBiologicalProcesschaperone cofactor-dependent protein refolding

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

3.11e-0735855GO:0051085
GeneOntologyBiologicalProcessnegative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

SLC25A4 SLC25A5 SLC25A6 HSPA1A

3.54e-0715854GO:1901029
GeneOntologyBiologicalProcessmitochondrial ADP transmembrane transport

SLC25A4 SLC25A5 SLC25A6

6.71e-075853GO:0140021
GeneOntologyBiologicalProcess'de novo' post-translational protein folding

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

7.04e-0741855GO:0051084
GeneOntologyBiologicalProcess'de novo' protein folding

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

1.27e-0646855GO:0006458
GeneOntologyBiologicalProcessregulation of inclusion body assembly

SACS HSPA1A HSPA1B HSPA2

1.52e-0621854GO:0090083
GeneOntologyBiologicalProcesspositive regulation of membrane permeability

SLC25A4 SLC25A5 SLC25A6 HSPA1A HSPA8

1.93e-0650855GO:1905710
GeneOntologyBiologicalProcessnegative regulation of mitochondrial membrane permeability

SLC25A4 SLC25A5 SLC25A6 HSPA1A

2.24e-0623854GO:0035795
GeneOntologyBiologicalProcessregulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

SLC25A4 SLC25A5 SLC25A6 HSPA1A

2.68e-0624854GO:1901028
GeneOntologyBiologicalProcessmitochondrial ATP transmembrane transport

SLC25A4 SLC25A5 SLC25A6

3.73e-068853GO:1990544
GeneOntologyBiologicalProcessnegative regulation of membrane permeability

SLC25A4 SLC25A5 SLC25A6 HSPA1A

3.75e-0626854GO:1905709
GeneOntologyBiologicalProcessprotein maturation

PCSK5 KAT2B SACS NCSTN MYRFL SERPINF2 HSPA1A HSPA1B HSPA2 F8 HSPA7 HSPA8

8.55e-066198512GO:0051604
GeneOntologyBiologicalProcessinclusion body assembly

SACS HSPA1A HSPA1B HSPA2

1.00e-0533854GO:0070841
GeneOntologyBiologicalProcessmitochondrial outer membrane permeabilization

SLC25A4 SLC25A5 SLC25A6 HSPA1A

1.00e-0533854GO:0097345
GeneOntologyBiologicalProcessresponse to heat

NF1 MAPKAPK2 HSPA1A HSPA1B HSPA2 HSPA8

1.08e-05121856GO:0009408
GeneOntologyBiologicalProcessADP transport

SLC25A4 SLC25A5 SLC25A6

1.45e-0512853GO:0015866
GeneOntologyBiologicalProcesschaperone-mediated protein folding

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

1.99e-0580855GO:0061077
GeneOntologyBiologicalProcesscellular response to heat

NF1 MAPKAPK2 HSPA1A HSPA1B HSPA8

2.11e-0581855GO:0034605
GeneOntologyBiologicalProcesspositive regulation of mitochondrial membrane permeability involved in apoptotic process

SLC25A4 SLC25A5 SLC25A6 HSPA1A

2.19e-0540854GO:1902110
GeneOntologyBiologicalProcessregulation of membrane permeability

SLC25A4 SLC25A5 SLC25A6 HSPA1A HSPA8

2.38e-0583855GO:0090559
GeneOntologyBiologicalProcessmitochondrial outer membrane permeabilization involved in programmed cell death

SLC25A4 SLC25A5 SLC25A6 HSPA1A

2.67e-0542854GO:1902686
GeneOntologyBiologicalProcesspositive regulation of mitochondrial membrane permeability

SLC25A4 SLC25A5 SLC25A6 HSPA1A

3.52e-0545854GO:0035794
GeneOntologyBiologicalProcessregulation of mitochondrial membrane permeability involved in apoptotic process

SLC25A4 SLC25A5 SLC25A6 HSPA1A

4.94e-0549854GO:1902108
GeneOntologyBiologicalProcessmyeloid cell homeostasis

NF1 SLC25A5 PIK3CB VPS13A NCSTN HSPA1A HSPA1B

6.04e-05240857GO:0002262
GeneOntologyBiologicalProcessATP transport

SLC25A4 SLC25A5 SLC25A6

1.13e-0423853GO:0015867
GeneOntologyBiologicalProcessregulation of mitochondrial membrane permeability

SLC25A4 SLC25A5 SLC25A6 HSPA1A

1.59e-0466854GO:0046902
GeneOntologyBiologicalProcessapoptotic mitochondrial changes

SLC25A4 SLC25A5 SLC25A6 HSPA1A MOAP1

1.95e-04129855GO:0008637
GeneOntologyBiologicalProcessmitochondrial membrane organization

SLC25A4 SLC25A5 SLC25A6 HSPA1A MOAP1

2.09e-04131855GO:0007006
GeneOntologyBiologicalProcessresponse to temperature stimulus

NF1 MAPKAPK2 HSPA1A HSPA1B HSPA2 HSPA8

2.21e-04208856GO:0009266
GeneOntologyBiologicalProcesscellular heat acclimation

HSPA1A HSPA1B

2.49e-046852GO:0070370
GeneOntologyBiologicalProcessadenine transport

SLC25A4 SLC25A5

2.49e-046852GO:0015853
GeneOntologyBiologicalProcessnucleotide transmembrane transport

SLC25A4 SLC25A5 SLC25A6

2.79e-0431853GO:1901679
GeneOntologyBiologicalProcessprotein localization to Golgi apparatus

ARL5C COG7 VPS13A

3.07e-0432853GO:0034067
GeneOntologyBiologicalProcessheat acclimation

HSPA1A HSPA1B

3.48e-047852GO:0010286
GeneOntologyBiologicalProcesspositive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

HSPA1A HSPA1B

3.48e-047852GO:0070434
GeneOntologyBiologicalProcessextrinsic apoptotic signaling pathway in absence of ligand

NF1 HSPA1A HSPA1B MOAP1

3.68e-0482854GO:0097192
GeneOntologyBiologicalProcessregulation of Rac protein signal transduction

DOCK2 NF1 PIK3CB

4.02e-0435853GO:0035020
GeneOntologyBiologicalProcesssignal transduction in absence of ligand

NF1 HSPA1A HSPA1B MOAP1

4.03e-0484854GO:0038034
GeneOntologyBiologicalProcesspositive regulation of microtubule nucleation

HSPA1A HSPA1B

4.62e-048852GO:0090063
GeneOntologyBiologicalProcesspositive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

HSPA1A HSPA1B

4.62e-048852GO:0070426
GeneOntologyBiologicalProcessprotein folding

SACS HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

5.40e-04246856GO:0006457
GeneOntologyBiologicalProcessregulation of mitochondrion organization

SLC25A4 SLC25A5 SLC25A6 HSPA1A MOAP1

5.56e-04162855GO:0010821
GeneOntologyBiologicalProcesspurine-containing compound transmembrane transport

SLC25A4 SLC25A5 SLC25A6

5.98e-0440853GO:0072530
GeneOntologyBiologicalProcesspurine ribonucleotide transport

SLC25A4 SLC25A5 SLC25A6

5.98e-0440853GO:0015868
GeneOntologyBiologicalProcessadenine nucleotide transport

SLC25A4 SLC25A5 SLC25A6

6.90e-0442853GO:0051503
GeneOntologyBiologicalProcesspurine nucleotide transport

SLC25A4 SLC25A5 SLC25A6

7.92e-0444853GO:0015865
GeneOntologyBiologicalProcessnegative regulation of cellular component organization

KAT2B SLC25A4 SLC25A5 SLC25A6 SACS SSH2 DENND5A HSPA1A HSPA1B HSPA2 HSPA8

8.23e-048648511GO:0051129
GeneOntologyBiologicalProcessregulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

HSPA1A HSPA1B

9.01e-0411852GO:0070432
GeneOntologyBiologicalProcesspositive regulation of myeloid cell apoptotic process

NF1 PIK3CB

9.01e-0411852GO:0033034
GeneOntologyBiologicalProcessmacropinocytosis

DOCK2 MAPKAPK2

9.01e-0411852GO:0044351
GeneOntologyBiologicalProcessbase-excision repair

ERCC6 POLE UNG

9.02e-0446853GO:0006284
GeneOntologyBiologicalProcesscellular response to chemical stress

KAT2B PYROXD1 VPS13A PNPLA8 HSPA1A HSPA1B HSPA8

9.37e-04377857GO:0062197
GeneOntologyCellularComponentblood microparticle

SERPINF2 HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

2.69e-05144856GO:0072562
GeneOntologyCellularComponentficolin-1-rich granule lumen

GUSB ACLY HSPA1A HSPA1B HSPA8

1.52e-04124855GO:1904813
GeneOntologyCellularComponentmitochondrial permeability transition pore complex

SLC25A4 SLC25A5

3.39e-047852GO:0005757
GeneOntologyCellularComponentsecretory granule lumen

DOCK2 GUSB ACLY VPS13A SERPINF2 F8 HSPA8

3.60e-04325857GO:0034774
GeneOntologyCellularComponentcytoplasmic vesicle lumen

DOCK2 GUSB ACLY VPS13A SERPINF2 F8 HSPA8

3.95e-04330857GO:0060205
GeneOntologyCellularComponentvesicle lumen

DOCK2 GUSB ACLY VPS13A SERPINF2 F8 HSPA8

4.09e-04332857GO:0031983
GeneOntologyCellularComponentCOP9 signalosome

HSPA1A HSPA1B HSPA7

4.94e-0438853GO:0008180
GeneOntologyCellularComponentsecretory granule

DOCK2 PTPRJ GUSB ACLY VPS13A NCSTN SSH2 SERPINF2 HSPA1A HSPA1B F8 HSPA8

7.96e-0410148512GO:0030141
GeneOntologyCellularComponentficolin-1-rich granule

GUSB ACLY HSPA1A HSPA1B HSPA8

9.52e-04185855GO:0101002
DomainHSP70

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

8.19e-0916875PF00012
DomainHSP70_2

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

1.16e-0817875PS00329
DomainHSP70_3

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

1.16e-0817875PS01036
DomainHSP70_1

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

1.16e-0817875PS00297
DomainHsp_70_fam

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

1.59e-0818875IPR013126
Domain-

HSPA1A HSPA2 HSPA8

2.08e-05128732.60.34.10
DomainHSP70_peptide-bd

HSPA1A HSPA2 HSPA8

2.08e-0512873IPR029047
DomainMit_uncoupling

SLC25A4 SLC25A5 SLC25A6

2.08e-0512873IPR002030
Domain-

HSPA1A HSPA2 HSPA8

2.70e-05138731.20.1270.10
DomainHeat_shock_70_CS

HSPA1A HSPA2 HSPA8

2.70e-0513873IPR018181
DomainHSP70_C

HSPA1A HSPA2 HSPA8

2.70e-0513873IPR029048
DomainAden_trnslctor

SLC25A4 SLC25A5 SLC25A6

2.94e-0428873IPR002113
DomainMit_carrier

SLC25A4 SLC25A5 SLC25A6

4.39e-0432873IPR002067
DomainSOLCAR

SLC25A4 SLC25A5 SLC25A6

1.93e-0353873PS50920
Domain-

SLC25A4 SLC25A5 SLC25A6

1.93e-03538731.50.40.10
DomainMitochondrial_sb/sol_carrier

SLC25A4 SLC25A5 SLC25A6

1.93e-0353873IPR018108
Domainp53-like_TF_DNA-bd

TBX3 TBX21 MYRFL

1.93e-0353873IPR008967
DomainMito_carr

SLC25A4 SLC25A5 SLC25A6

1.93e-0353873PF00153
DomainMt_carrier_dom

SLC25A4 SLC25A5 SLC25A6

1.93e-0353873IPR023395
DomainTF_T-box

TBX3 TBX21

2.79e-0317872IPR001699
DomainTBOX

TBX3 TBX21

2.79e-0317872SM00425
DomainTF_T-box_CS

TBX3 TBX21

2.79e-0317872IPR018186
Domain-

TBX3 TBX21

2.79e-03178722.60.40.820
DomainTBOX_3

TBX3 TBX21

2.79e-0317872PS50252
DomainAcyl_Trfase/lysoPLipase

PNPLA8 MCAT

2.79e-0317872IPR016035
DomainT-box

TBX3 TBX21

2.79e-0317872PF00907
DomainTBOX_1

TBX3 TBX21

2.79e-0317872PS01283
DomainTBOX_2

TBX3 TBX21

2.79e-0317872PS01264
DomainRUN

SGSM1 DENND5A

3.13e-0318872SM00593
DomainRUN

SGSM1 DENND5A

3.48e-0319872PS50826
DomainRUN

SGSM1 DENND5A

3.48e-0319872PF02759
DomainRun_dom

SGSM1 DENND5A

3.48e-0319872IPR004012
Domain-

PCSK5 GUSB F8

4.80e-03738732.60.120.260
DomainTyr_Pase_AS

TPTE PTPRJ SSH2

4.80e-0373873IPR016130
DomainTYR_PHOSPHATASE_1

TPTE PTPRJ SSH2

7.56e-0386873PS00383
DomainTYR_PHOSPHATASE_2

TPTE PTPRJ SSH2

7.81e-0387873PS50056
DomainTYR_PHOSPHATASE_dom

TPTE PTPRJ SSH2

7.81e-0387873IPR000387
Domain-

TPTE PTPRJ SSH2

9.10e-03928733.90.190.10
PathwayREACTOME_ATTENUATION_PHASE

HSPA1A HSPA1B HSPA2 HSPA8

2.35e-0713624MM14952
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSPA1A HSPA1B HSPA2 HSPA8

2.82e-0623624MM14953
PathwayREACTOME_ATTENUATION_PHASE

HSPA1A HSPA1B HSPA2 HSPA8

6.42e-0628624M27254
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01006

SLC25A4 SLC25A5 SLC25A6

9.51e-0610623M47694
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

MAPKAPK2 HSPA1A HSPA1B HSPA2 HSPA8

1.67e-0573625MM14948
PathwayREACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE

SLC25A4 SLC25A5 SLC25A6

1.73e-0512623M27728
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSPA1A HSPA1B HSPA2 HSPA8

2.24e-0538624M27255
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

2.25e-0513623M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

2.25e-0513623M47751
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_VGCC_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

2.25e-0513623M47703
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004

SLC25A4 SLC25A5 SLC25A6

2.85e-0514623M47692
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

MAPKAPK2 HSPA1A HSPA1B HSPA2 HSPA8

2.94e-0582625M27250
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM

SLC25A4 SLC25A5 SLC25A6

3.55e-0515623M47691
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

4.36e-0516623M47695
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

MAPKAPK2 HSPA1A HSPA1B HSPA2 HSPA8

5.12e-0592625MM14951
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

6.31e-0518623M47659
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM

SLC25A4 SLC25A5 SLC25A6

6.31e-0518623M47761
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM

SLC25A4 SLC25A5 SLC25A6

7.47e-0519623M47677
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

7.47e-0519623M47760
PathwayREACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND

HSPA1A HSPA1B HSPA2 HSPA8

7.84e-0552624MM14949
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

MAPKAPK2 HSPA1A HSPA1B HSPA2 HSPA8

8.00e-05101625M27253
PathwayKEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

8.76e-0520623M47688
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

1.02e-0421623M47689
PathwayREACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND

HSPA1A HSPA1B HSPA2 HSPA8

1.13e-0457624M27251
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

1.18e-0422623M47690
PathwayKEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

1.18e-0422623M47675
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

1.35e-0423623M47666
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

1.35e-0423623M47676
PathwayREACTOME_PKR_MEDIATED_SIGNALING

HSPA1A HSPA1B HSPA2 HSPA8

1.99e-0466624MM17074
PathwayKEGG_SPLICEOSOME

NCBP1 HSPA1A HSPA1B HSPA2 HSPA8

2.35e-04127625M2044
PathwayWP_PARKINUBIQUITIN_PROTEASOMAL_SYSTEM_PATHWAY

HSPA1A HSPA1B HSPA2 HSPA8

2.64e-0471624M39690
PathwayWP_MEASLES_VIRUS_INFECTION

PIK3CB HSPA1A HSPA1B HSPA2 HSPA8

3.23e-04136625M42547
PathwayREACTOME_PKR_MEDIATED_SIGNALING

HSPA1A HSPA1B HSPA2 HSPA8

3.43e-0476624M48037
PathwayREACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS

MAPKAPK2 HSPA1A HSPA1B HSPA8

5.50e-0486624MM15140
PathwayREACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS

SLC25A4 SLC25A5 SLC25A6

5.66e-0437623M1029
PathwayKEGG_ANTIGEN_PROCESSING_AND_PRESENTATION

HSPA1A HSPA1B HSPA2 HSPA8

6.00e-0488624M16004
PathwayWP_MAPK_SIGNALING_PATHWAY

NF1 MAPKAPK2 HSPA1A HSPA1B HSPA8

6.80e-04160625MM15990
PathwayWP_MAPK_SIGNALING

NF1 MAPKAPK2 HSPA1A HSPA1B HSPA2 HSPA8

7.22e-04246626M39597
PathwayREACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

HSPA1A HSPA1B HSPA2 HSPA8

7.69e-0494624MM14515
PathwayBIOCARTA_ETC_PATHWAY

SLC25A4 SLC25A6

8.37e-0410622M15371
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLC25A4 SLC25A5 SLC25A6

8.82e-0443623M881
PathwayWP_NOTCH_SIGNALING_WP268

KAT2B KCNJ5 NCSTN

1.01e-0345623M39571
PathwayREACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE

SLC25A4 SLC25A5

1.02e-0311622MM15471
PathwayKEGG_MAPK_SIGNALING_PATHWAY

NF1 MAPKAPK2 HSPA1A HSPA1B HSPA2 HSPA8

1.10e-03267626M10792
PathwayREACTOME_NEUTROPHIL_DEGRANULATION

DOCK2 PTPRJ GUSB ACLY NCSTN HSPA1A HSPA1B HSPA8

1.12e-03478628M27620
PathwayREACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_INITIATION

KAT2B ERCC6 CHD3

1.14e-0347623M1095
PathwayKEGG_ENDOCYTOSIS

RAB11FIP2 HSPA1A HSPA1B HSPA2 HSPA8

1.18e-03181625M1519
PathwayREACTOME_NEUTROPHIL_DEGRANULATION

DOCK2 PTPRJ GUSB ACLY NCSTN HSPA1A HSPA1B HSPA8

1.71e-03511628MM15330
PathwayREACTOME_AUF1_HNRNP_D0_BINDS_AND_DESTABILIZES_MRNA

HSPA1A HSPA1B HSPA8

1.81e-0355623MM15137
Pubmed

Function and regulation of heat shock factor 2 during mouse embryogenesis.

HSPA1A HSPA1B HSPA2 HSPA8

2.54e-0988749122205
Pubmed

Reciprocal regulation of human immunodeficiency virus-1 gene expression and replication by heat shock proteins 40 and 70.

HSPA1A HSPA1B HSPA2 HSPA8

4.56e-09987421763498
Pubmed

Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein.

HSPA1A HSPA1B HSPA2 HSPA8

7.58e-09108747906708
Pubmed

Specific incorporation of heat shock protein 70 family members into primate lentiviral virions.

HSPA1A HSPA1B HSPA2 HSPA8

7.58e-091087411932435
Pubmed

gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120.

HSPA1A HSPA1B HSPA2 HSPA8

7.58e-091087412832005
Pubmed

Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation.

HSPA1A HSPA1B HSPA2 HSPA8

7.58e-091087423921388
Pubmed

HSPA1A, HSPA2, and HSPA8 Are Potential Molecular Biomarkers for Prognosis among HSP70 Family in Alzheimer's Disease.

HSPA1A HSPA2 HSPA8

1.51e-08387336246562
Pubmed

Functional analysis of HSPA1A and HSPA8 in parturition.

HSPA1A HSPA1B HSPA8

1.51e-08387328025138
Pubmed

The human mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae.

SLC25A4 SLC25A5 SLC25A6

1.51e-08387312450408
Pubmed

Electrophoretic and immunocytochemical analysis of Hsp72 and Hsp73 expression in heat-stressed mouse testis and epididymis.

HSPA1A HSPA1B HSPA8

1.51e-08387323352621
Pubmed

DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase.

SLC25A4 SLC25A5 SLC25A6

1.51e-0838732541251
Pubmed

Stored of Hsp72/Hsp73 in germinal vesicle-stage mouse oocytes.

HSPA1A HSPA1B HSPA8

1.51e-08387315129916
Pubmed

Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver.

SLC25A4 SLC25A5 SLC25A6

1.51e-0838732829183
Pubmed

Differential expression of HSPA1 and HSPA2 proteins in human tissues; tissue microarray-based immunohistochemical study.

HSPA1A HSPA1B HSPA2

1.51e-08387321373891
Pubmed

HIV-1 viral protein R (Vpr) and its interactions with host cell.

HSPA1A HSPA1B HSPA2 HSPA8

1.78e-081287419275587
Pubmed

Mitochondrial membrane permeabilization by HIV-1 Vpr.

SLC25A4 SLC25A5 SLC25A6 UNG

1.78e-081287416120388
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MRPS10 STIM2 SLC25A6 SACS GUSB POLE VPS13A PNPLA8 TYW1 ZFC3H1 PAF1 USP48 DDX24 HSPA1A HSPA1B HSPA2 HSPA8 DMXL1

2.39e-081487871833957083
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SLC25A4 SLC25A5 SLC25A6 SSH2 ZFC3H1 HSPA1A HSPA2 HSPA8

2.44e-0818787826460568
Pubmed

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.

HSPA1A HSPA1B HSPA2 HSPA8

2.57e-081387427477512
Pubmed

Molecular composition of IMP1 ribonucleoprotein granules.

NCBP1 RO60 HSPA1A HSPA1B HSPA8

3.09e-083687517289661
Pubmed

Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.

HSPA1A HSPA1B HSPA2 HSPA8

4.88e-081587410964507
Pubmed

Differential Expression of ADP/ATP Carriers as a Biomarker of Metabolic Remodeling and Survival in Kidney Cancers.

SLC25A4 SLC25A5 SLC25A6

6.04e-08487333396658
Pubmed

Variations in HSP70 genes associated with noise-induced hearing loss in two independent populations.

HSPA1A HSPA1B HSPA2

6.04e-08487318813331
Pubmed

Delayed temporal increase of hepatic Hsp70 in ApoE knockout mice after prenatal arsenic exposure.

HSPA1A HSPA1B HSPA8

6.04e-08487322956628
Pubmed

Upregulation of the constitutively expressed HSC70 by KLF4.

HSPA1A HSPA1B HSPA8

6.04e-08487318379898
Pubmed

Association analysis of heat shock protein 70 gene polymorphisms in schizophrenia.

HSPA1A HSPA1B HSPA8

6.04e-08487318299791
Pubmed

Clathrin facilitates the morphogenesis of retrovirus particles.

HSPA1A HSPA1B HSPA2 HSPA8

6.50e-081687421738476
Pubmed

Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2.

SLC25A4 SLC25A5 SLC25A6 HSPA1B HSPA7 HSPA8

1.40e-079487636584595
Pubmed

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration.

HSPA1A HSPA1B HSPA8

1.51e-07587316906134
Pubmed

HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain.

HSPA1A HSPA1B HSPA8

1.51e-07587317182002
Pubmed

A DnaJ protein, apobec-1-binding protein-2, modulates apolipoprotein B mRNA editing.

HSPA1A HSPA1B HSPA8

1.51e-07587311584023
Pubmed

Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function.

SLC25A5 SLC25A6 ACLY HSPA1A HSPA8

2.75e-075587529111377
Pubmed

Heat shock factor 2 is activated during mouse heart development.

HSPA1A HSPA1B HSPA8

3.01e-07687311032181
Pubmed

Genetic aspects of the hsp70 multigene family in vertebrates.

HSPA1A HSPA1B HSPA8

3.01e-0768737988674
Pubmed

Phosphorylation and binding partner analysis of the TSC1-TSC2 complex.

HSPA1A HSPA1B HSPA8

3.01e-07687315963462
Pubmed

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.

SLC25A4 SLC25A5 SLC25A6

3.01e-07687310620603
Pubmed

BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

HSPA1A HSPA1B HSPA8

3.01e-0768739305631
Pubmed

RING finger protein RNF207, a novel regulator of cardiac excitation.

HSPA1A HSPA1B HSPA8

3.01e-07687325281747
Pubmed

The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.

HSPA1A HSPA1B HSPA2 HSPA8

3.12e-072387421231916
Pubmed

USP7 controls NGN3 stability and pancreatic endocrine lineage development.

SLC25A5 SLC25A6 HSPA1A HSPA1B HSPA8

3.60e-075887537117185
Pubmed

Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription.

HSPA1A HSPA1B HSPA2 HSPA8

3.74e-072487410617616
Pubmed

Expression of leucine-rich repeat kinase 2 (LRRK2) inhibits the processing of uMtCK to induce cell death in a cell culture model system.

SLC25A4 SLC25A5 SLC25A6

5.25e-07787321370995
Pubmed

Control of mRNA decay by heat shock-ubiquitin-proteasome pathway.

HSPA1A HSPA1B HSPA8

5.25e-07787310205060
Pubmed

TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood.

SLC25A4 SLC25A5 SLC25A6

8.39e-07887327641616
Pubmed

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy.

HSPA1A HSPA1B HSPA2

8.39e-07887322495301
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

MRPS10 SLC25A4 SLC25A5 SLC25A6 ACLY NCBP1 RO60 CHD3 PPA1 NCSTN PAF1 HSPA2 HSPA7 HSPA8

1.02e-061153871429845934
Pubmed

Quantitative analysis of PPT1 interactome in human neuroblastoma cells.

SLC25A4 SLC25A5 SLC25A6 ACLY HSPA1B HSPA2 HSPA8

1.03e-0621087726217791
Pubmed

Identification of Redox and Glucose-Dependent Txnip Protein Interactions.

SCML2 HSPA1A HSPA1B HSPA8

1.24e-063287427437069
Pubmed

Chromosomal localization of five murine HSP70 gene family members: Hsp70-1, Hsp70-2, Hsp70-3, Hsc70t, and Grp78.

HSPA1A HSPA1B HSPA2

1.26e-0698738486356
Pubmed

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.

SERPINF2 HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

1.67e-0614387622516433
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

SLC25A4 SLC25A5 SLC25A6 ACLY NCBP1 CHD3 DDX24 HSPA1A HSPA1B HSPA2 HSPA8

1.72e-06714871128302793
Pubmed

Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS.

HSPA1B HSPA2 HSPA8

1.79e-061087319171884
Pubmed

A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.

RO60 HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

1.81e-0614587623349634
Pubmed

TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A.

ERCC6 HSPA1B HSPA2 HSPA8

2.26e-063787429531219
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

NF1 ARSL PTPRJ COG7 GUSB PPP4R2 VPS13A MGLL TYW1 PPA1 HSPA1A HSPA2 HSPA8

2.33e-061061871333845483
Pubmed

SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation.

SLC25A4 SLC25A5 SLC25A6 HSPA1A HSPA1B HSPA2 HSPA8

2.43e-0623987723246001
Pubmed

ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation.

HSPA1A HSPA1B HSPA8

2.46e-061187327708256
Pubmed

Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro.

HSPA1A HSPA1B HSPA8

2.46e-061187324318877
Pubmed

Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence.

SLC25A5 HSPA1A HSPA1B HSPA2 HSPA8

2.90e-068887525144556
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

PTPRJ SLC25A5 SLC25A6 GUSB PPA1 NCSTN HSPA1A HSPA1B HSPA8 FBXL5

3.18e-06613871022268729
Pubmed

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity.

HSPA1A HSPA1B HSPA8

3.27e-061287312150907
Pubmed

Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane.

SLC25A4 HSPA1A HSPA1B

3.27e-061287318385140
Pubmed

The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25.

ACLY HSPA1A HSPA1B

3.27e-061287324399297
Pubmed

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.

SLC25A4 SLC25A5 SLC25A6 PIK3CB VPS13A HSPA1A HSPA8

3.82e-0625687724189400
Pubmed

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.

SLC25A5 ACLY HSPA1A HSPA1B HSPA2 HSPA8

3.96e-0616687635687106
Pubmed

A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells.

HSPA1A HSPA1B HSPA8

4.25e-061387330792309
Pubmed

Vpr-host interactions during HIV-1 viral life cycle.

SLC25A4 UNG HSPA1A

4.25e-061387321318276
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

SLC25A5 SLC25A6 PIK3CB ACLY HSPA1B HSPA7 HSPA8

4.91e-0626687719380743
Pubmed

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.

SLC25A5 ACLY HSPA1A HSPA1B HSPA7 HSPA8

5.37e-0617587625756610
Pubmed

Cold/menthol TRPM8 receptors initiate the cold-shock response and protect germ cells from cold-shock-induced oxidation.

HSPA1A HSPA1B HSPA2

5.39e-061487327317670
Pubmed

A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair.

ERCC6 PAF1

6.19e-06287233637760
Pubmed

Exercise induces hepatosplanchnic release of heat shock protein 72 in humans.

HSPA1A HSPA1B

6.19e-06287212411538
Pubmed

Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.

HSPA1A HSPA1B

6.19e-0628722868009
Pubmed

Role of adenine nucleotide translocator 1 in mtDNA maintenance.

SLC25A4 SLC25A6

6.19e-06287210926541
Pubmed

Genetic manipulation of cardiac Hsp72 levels does not alter substrate metabolism but reveals insights into high-fat feeding-induced cardiac insulin resistance.

HSPA1A HSPA1B

6.19e-06287225618331
Pubmed

Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.

HSPA1A HSPA1B

6.19e-06287224328534
Pubmed

In vitro transcription of a human hsp 70 heat shock gene by extracts prepared from heat-shocked and non-heat-shocked human cells.

HSPA1A HSPA1B

6.19e-0628723786141
Pubmed

Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury.

HSPA1A HSPA1B

6.19e-06287216679378
Pubmed

HSP70-2 is part of the synaptonemal complex in mouse and hamster spermatocytes.

HSPA1B HSPA2

6.19e-0628728601336
Pubmed

Inducible 70 kDa heat shock proteins protect embryos from teratogen-induced exencephaly: Analysis using Hspa1a/a1b knockout mice.

HSPA1A HSPA1B

6.19e-06287219639652
Pubmed

Effect of mutation of amino acids 246-251 (KRKHKK) in HSP72 on protein synthesis and recovery from hypoxic injury.

HSPA1A HSPA1B

6.19e-06287216100242
Pubmed

Role of the C-terminal region of mouse inducible Hsp72 in the recognition of peptide substrate for chaperone activity.

HSPA1A HSPA1B

6.19e-06287215498567
Pubmed

Biological activity of truncated C-terminus human heat shock protein 72.

HSPA1A HSPA1B

6.19e-06287221094186
Pubmed

Processing of U14 small nucleolar RNA from three different introns of the mouse 70-kDa-cognate-heat-shock-protein pre-messenger RNA.

HSPA1B HSPA8

6.19e-0628727813466
Pubmed

Characterization of the binding between a 70-kDa heat shock protein, HspA1A, and phosphoinositides.

HSPA1A HSPA1B

6.19e-06287226923070
Pubmed

Surface expression of HSP72 by LPS-stimulated neutrophils facilitates gammadeltaT cell-mediated killing.

HSPA1A HSPA1B

6.19e-06287216482515
Pubmed

Geranylgeranylaceton induces heat shock protein 72 in skeletal muscle cells.

HSPA1A HSPA1B

6.19e-06287217482577
Pubmed

Effect of hyaluronan oligosaccharides on the expression of heat shock protein 72.

HSPA1A HSPA1B

6.19e-06287211864979
Pubmed

Structure and expression of an inducible HSP70-encoding gene from Mus musculus.

HSPA1A HSPA1B

6.19e-0628728076831
Pubmed

The 70 kDa heat shock protein protects against experimental traumatic brain injury.

HSPA1A HSPA1B

6.19e-06287223816752
Pubmed

Hippocampal 72-kDa heat shock protein expression varies according to mice learning performance independently from chronic exposure to stress.

HSPA1A HSPA1B

6.19e-06287215719414
Pubmed

Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.

HSPA1A HSPA1B

6.19e-06287226976620
Pubmed

Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody.

HSPA1A HSPA1B

6.19e-06287221187371
Pubmed

Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer.

HSPA1A HSPA1B

6.19e-06287220430459
Pubmed

Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia.

HSPA1A HSPA1B

6.19e-06287220235222
Pubmed

Genetic determinants of HSP70 gene expression following heat shock.

HSPA1A HSPA1B

6.19e-06287220876613
Pubmed

The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange.

HSPA1A HSPA1B

6.19e-06287220223214
Pubmed

Association between heat shock protein 72 gene polymorphism and acute renal failure in premature neonates.

HSPA1A HSPA8

6.19e-06287212840151
Pubmed

Heat-shock protein HSP70-2 genotypes in patients with Crohn's disease: a more severe clinical course with intestinal complications in presence of the PstI-polymorphism.

HSPA1B HSPA2

6.19e-06287212730033
Pubmed

Structure of a new crystal form of human Hsp70 ATPase domain.

HSPA1A HSPA1B

6.19e-06287210216320
InteractionMETTL21A interactions

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

4.03e-0736855int:METTL21A
InteractionCCDC117 interactions

HSPA1A HSPA1B HSPA2 HSPA8

4.10e-0626854int:CCDC117
InteractionNDRG2 interactions

SLC25A6 USP48 HSPA1B HSPA2 HSPA8

4.18e-0657855int:NDRG2
InteractionPAK1 interactions

SLC25A4 SLC25A5 SLC25A6 LPXN HSPA1A HSPA2 HSPA7 HSPA8

5.58e-06229858int:PAK1
InteractionGAN interactions

SLC25A4 SLC25A5 SLC25A6 SSH2 ZFC3H1 HSPA1A HSPA2 HSPA8

1.15e-05253858int:GAN
InteractionFAM83F interactions

HSPA1A HSPA1B HSPA2 HSPA8

1.57e-0536854int:FAM83F
InteractionPABPC4 interactions

TBX3 POLE NCBP1 RO60 CHD3 PPA1 ZFC3H1 HSPA1A HSPA2 HSPA8

1.68e-054428510int:PABPC4
InteractionCYP2W1 interactions

HSPA1B HSPA2 HSPA8

3.18e-0515853int:CYP2W1
InteractionPRODH interactions

ACY1 HSPA2 HSPA8

3.90e-0516853int:PRODH
InteractionNEUROG3 interactions

SLC25A5 SLC25A6 PAF1 HSPA1A HSPA1B HSPA8

3.99e-05149856int:NEUROG3
InteractionTRIM38 interactions

HSPA1A HSPA1B HSPA2 HSPA8

4.58e-0547854int:TRIM38
InteractionC3orf38 interactions

HSPA1A HSPA2 HSPA8

4.72e-0517853int:C3orf38
InteractionBPNT1 interactions

MAPKAPK2 ACY1 USP48 HSPA1A HSPA8

5.36e-0596855int:BPNT1
InteractionPRKCZ interactions

SLC25A4 SLC25A5 SLC25A6 ACLY PPA1 DENND5A HSPA1A HSPA7 HSPA8

5.97e-05412859int:PRKCZ
InteractionTGM2 interactions

SLC25A5 SLC25A6 RO60 SERPINF2 HSPA1A HSPA1B HSPA8

6.11e-05235857int:TGM2
InteractionAR interactions

TBX3 KAT2B SCML2 SLC25A4 SLC25A5 SLC25A6 KDM4C ACLY CHD3 DENND5A ACY1 USP48 HSPA1A HSPA8

6.48e-059928514int:AR
InteractionHNRNPA2B1 interactions

ERCC6 SLC25A5 ACLY NCBP1 RO60 CHD3 USP48 DDX24 HSPA1A HSPA1B F8 HSPA8

7.40e-057548512int:HNRNPA2B1
InteractionHNRNPD interactions

KAT2B COG7 ACLY NCBP1 PNPLA8 RO60 CHD3 USP48 DDX24 HSPA1A HSPA8

7.48e-056388511int:HNRNPD
InteractionDNAJC7 interactions

NF1 SACS POLE VPS13A HSPA1A HSPA1B HSPA2 HSPA8 DMXL1

7.57e-05425859int:DNAJC7
InteractionMAP3K14 interactions

SLC25A4 SLC25A5 SLC25A6 HSPA1A HSPA7 HSPA8

8.05e-05169856int:MAP3K14
InteractionPRKCE interactions

SLC25A4 SLC25A5 SLC25A6 PIK3CB HSPA1A HSPA8

9.16e-05173856int:PRKCE
InteractionADRB2 interactions

TPTE SLC25A5 SLC25A6 SACS KCNJ5 MGLL HSPA1A HSPA1B

9.22e-05339858int:ADRB2
InteractionZUP1 interactions

NF1 POLE HSPA1A HSPA2 HSPA8 CCDC93

9.45e-05174856int:ZUP1
InteractionHNRNPU interactions

MRPS10 KAT2B ERCC6 SLC25A5 PPP4R2 NCBP1 RO60 CHD3 MCAT NCSTN USP48 DDX24 HSPA1A HSPA8

1.02e-0410358514int:HNRNPU
InteractionPPT1 interactions

SLC25A4 SLC25A5 SLC25A6 ACLY HSPA1B HSPA2 HSPA8

1.04e-04256857int:PPT1
InteractionUBL4A interactions

SLC25A4 SLC25A5 SLC25A6 NCBP1 HSPA1A HSPA1B HSPA2 HSPA8

1.13e-04349858int:UBL4A
InteractionLGR4 interactions

TPTE SLC25A5 CHD3 TYW1 ZFC3H1 HS3ST1 HSPA2

1.21e-04262857int:LGR4
InteractionSSR1 interactions

STIM2 VPS13A TYW1 MAP3K15 SERPINF2 USP48 DDX24 HSPA1A HSPA1B

1.23e-04453859int:SSR1
InteractionNCL interactions

ERCC6 SLC25A5 ACLY RAB11FIP2 NCBP1 RO60 CHD3 PPA1 USP48 DDX24 HSPA1A HSPA8

1.26e-047988512int:NCL
InteractionGNAT2 interactions

VPS13A USP48 HSPA1A

1.37e-0424853int:GNAT2
InteractionRBMX interactions

TBX3 ERCC6 NKX2-1 ACLY CHD3 MCAT USP48 HSPA1A HSPA8

1.40e-04461859int:RBMX
InteractionLIME1 interactions

DPY19L1 HSPA1B HSPA2 HSPA8

1.45e-0463854int:LIME1
InteractionACTR1A interactions

KLHL2 SSH2 DENND5A ZFC3H1 USP48 HSPA1A HSPA8

1.59e-04274857int:ACTR1A
InteractionACTB interactions

KAT2B SLC25A4 COG7 ACLY VPS13A NCBP1 PNPLA8 RO60 CHD3 SSH2 USP48 HSPA1A HSPA8 FBXL5

1.64e-0410838514int:ACTB
InteractionOPN1SW interactions

USP48 HSPA8

1.74e-045852int:OPN1SW
InteractionRAN interactions

SLC25A6 NKX2-1 ACLY NCBP1 CHD3 PPA1 USP48 HSPA1A HSPA8

1.75e-04475859int:RAN
InteractionKHDRBS1 interactions

DOCK2 ERCC6 ACLY RO60 CHD3 NCSTN USP48 HSPA8

1.78e-04373858int:KHDRBS1
InteractionELK1 interactions

SLC25A5 SLC25A6 HSPA1A HSPA7 HSPA8

1.87e-04125855int:ELK1
InteractionSLC25A20 interactions

SLC25A5 SLC25A6 HSPA2 HSPA8

2.07e-0469854int:SLC25A20
InteractionARMC5 interactions

SLC25A5 ACLY HSPA1A HSPA1B HSPA2 HSPA8

2.08e-04201856int:ARMC5
InteractionLARP7 interactions

MRPS10 SLC25A4 SLC25A5 SLC25A6 ACLY NCBP1 RO60 PAF1 DDX24 HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

2.18e-0411138514int:LARP7
InteractionYWHAE interactions

STIM2 NF1 TTC28 SLC25A5 SLC25A6 ACLY RAB11FIP2 NCBP1 RO60 MAP3K15 SSH2 USP48 DDX24 HSPA1A HSPA8

2.22e-0412568515int:YWHAE
InteractionHSF1 interactions

SLC25A5 SLC25A6 MAPKAPK2 ACLY NCBP1 RO60 CHD3 HSPA1A HSPA2 HSPA8

2.41e-046098510int:HSF1
InteractionFTCD interactions

HSPA1A HSPA1B HSPA2

2.44e-0429853int:FTCD
InteractionFBXL15 interactions

HSPA1B HSPA2 HSPA8

2.44e-0429853int:FBXL15
InteractionGGCT interactions

PPA1 DDX24 HSPA1A HSPA8

2.57e-0473854int:GGCT
InteractionTXNIP interactions

SCML2 SLC25A6 NCBP1 HSPA1A HSPA1B HSPA8

2.77e-04212856int:TXNIP
InteractionH2AC4 interactions

KAT2B SCML2 ERCC6 SLC25A6 CHD3 USP48 DDX24 HSPA1A HSPA8

2.80e-04506859int:H2AC4
InteractionACTN4 interactions

SACS KDM4C NCBP1 RO60 USP48 DDX24 HSPA1A HSPA8

2.85e-04400858int:ACTN4
InteractionINPPL1 interactions

SLC25A5 SLC25A6 ACLY PPP4R2 HSPA1B HSPA8

2.91e-04214856int:INPPL1
InteractionH3-3A interactions

KAT2B SCML2 ERCC6 NKX2-1 KDM4C NCBP1 UNG RO60 CHD3 USP48 ZHX1

3.03e-047498511int:H3-3A
InteractionF12 interactions

NF1 HSPA1B HSPA2 HSPA8

3.15e-0477854int:F12
InteractionSLC25A3 interactions

TBX3 SLC25A4 NKX2-1 CHD3 USP48 DDX24 HSPA1A HSPA8

3.42e-04411858int:SLC25A3
InteractionHSF2 interactions

NCBP1 HSPA1A HSPA2 HSPA8

3.48e-0479854int:HSF2
InteractionMAPK7 interactions

SLC25A4 SLC25A5 SLC25A6 HSPA1A HSPA8

3.49e-04143855int:MAPK7
InteractionPRKCI interactions

MRPS10 SLC25A4 SLC25A5 SLC25A6 HSPA1A HSPA7 HSPA8

3.57e-04313857int:PRKCI
InteractionPNPLA5 interactions

HSPA1B HSPA2 HSPA8

3.61e-0433853int:PNPLA5
InteractionAP5Z1 interactions

HSPA1B HSPA2 HSPA8

3.61e-0433853int:AP5Z1
InteractionRNF207 interactions

HSPA1A HSPA8

3.64e-047852int:RNF207
InteractionDNAJB4 interactions

ACY1 HSPA1A HSPA1B HSPA2 HSPA8

3.72e-04145855int:DNAJB4
InteractionLIPC interactions

SLC25A4 SLC25A5 HSPA8

3.94e-0434853int:LIPC
InteractionTGM1 interactions

DOCK2 SCML2 SLC25A6 UNG HSPA1A HSPA8

4.08e-04228856int:TGM1
InteractionTACC3 interactions

KAT2B SLC25A4 ZFC3H1 HSPA1A HSPA8

4.08e-04148855int:TACC3
InteractionTBX5 interactions

SCML2 SLC25A5 TBX21 HSPA1A HSPA8

4.34e-04150855int:TBX5
InteractionGABRA1 interactions

SLC25A4 SLC25A5 SLC25A6 HSPA1A HSPA8

4.61e-04152855int:GABRA1
InteractionVDAC1 interactions

SLC25A4 SLC25A5 DPY19L1 SLC25A6 CHD3 PAF1 USP48 DDX24 HSPA8

4.62e-04542859int:VDAC1
InteractionSLC25A5 interactions

SLC25A4 SLC25A5 SLC25A6 CHD3 NCSTN USP48 DDX24 HSPA8

4.69e-04431858int:SLC25A5
InteractionPHC1 interactions

MAPKAPK2 PAF1 HSPA2 HSPA8

4.81e-0486854int:PHC1
InteractionCT45A2 interactions

PPP4R2 HSPA1A

4.84e-048852int:CT45A2
InteractionKRT78 interactions

CHD3 DDX24 HSPA1A HSPA8

5.03e-0487854int:KRT78
InteractionSAE1 interactions

ERCC6 PPA1 USP48 HSPA1A HSPA2

5.04e-04155855int:SAE1
InteractionTFCP2 interactions

SLC25A4 SLC25A5 SLC25A6 NKX2-1 HSPA1A HSPA2 HSPA7 HSPA8

5.06e-04436858int:TFCP2
InteractionKCNC4 interactions

TYW1 HSPA2 HSPA8

5.07e-0437853int:KCNC4
InteractionTTC1 interactions

NCBP1 ACY1 HSPA1A HSPA2 HSPA8

5.19e-04156855int:TTC1
InteractionCASP14 interactions

SLC25A6 CHD3 DDX24 HSPA1A HSPA8

5.19e-04156855int:CASP14
InteractionMYCN interactions

MRPS10 KAT2B SLC25A4 SLC25A5 SLC25A6 ACLY NCBP1 RO60 MCAT PPA1 ZFC3H1 DDX24 HSPA1B HSPA2 HSPA8

5.72e-0413738515int:MYCN
InteractionMCM2 interactions

DOCK2 SLC25A4 SLC25A5 SLC25A6 NKX2-1 ACLY PPP4R2 CHD3 PAF1 HSPA1A HSPA2 HSPA7 HSPA8

5.73e-0410818513int:MCM2
InteractionGRB10 interactions

PAF1 DDX24 HSPA1A HSPA7 HSPA8

5.99e-04161855int:GRB10
InteractionGADL1 interactions

HSPA2 HSPA8

6.21e-049852int:GADL1
InteractionADAD2 interactions

HSPA2 HSPA8

6.21e-049852int:ADAD2
InteractionCCNI2 interactions

HSPA1B HSPA8

6.21e-049852int:CCNI2
InteractionHLA-DPB1 interactions

STIM2 SLC25A4 SLC25A6 GID4

6.47e-0493854int:HLA-DPB1
InteractionNDN interactions

ARSL SLC25A5 SLC25A6 LPXN PPA1 DDX24 HSPA1A HSPA8

6.50e-04453858int:NDN
InteractionSIRT2 interactions

KAT2B SLC25A5 ACLY MOAP1 HSPA8

6.70e-04165855int:SIRT2
InteractionCOQ2 interactions

SLC25A4 SLC25A5 DPY19L1 SLC25A6

6.73e-0494854int:COQ2
InteractionPELI3 interactions

HSPA1B HSPA2 HSPA8

6.88e-0441853int:PELI3
CytobandEnsembl 112 genes in cytogenetic band chrXp22

SCML2 ARSL SLC25A6 MAP3K15

1.34e-03250874chrXp22
CytobandEnsembl 112 genes in cytogenetic band chr4p15

STIM2 HS3ST1 FBXL5

2.20e-03135873chr4p15
Cytoband16p12.2

VWA3A COG7

2.26e-033787216p12.2
GeneFamilyHeat shock 70kDa proteins

HSPA1A HSPA1B HSPA2 HSPA7 HSPA8

2.62e-0917635583
CoexpressionKRISHNAN_FURIN_TARGETS_UP

HSPA1A HSPA1B HSPA8

4.17e-0610873MM1243
CoexpressionHEVNER_CORTEX_COMMITTED_TO_CALLOSAL_PROJECTION_NEURON_FATE

TTC28 DPY19L1 HS3ST1

3.87e-0520873MM423
CoexpressionGSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_DN

PCSK5 DPY19L1 PIK3CB MGLL DDX24 HSPA2

5.38e-05199876M9599
CoexpressionGSE3982_MAST_CELL_VS_CENT_MEMORY_CD4_TCELL_UP

KLHL2 DPY19L1 LPXN ACY1 USP48 HS3ST1

5.38e-05199876M5446
CoexpressionGSE23695_CD57_POS_VS_NEG_NK_CELL_DN

ACLY DENND5A HSPA1B ZHX1 MOAP1 CCDC93

5.53e-05200876M7786
CoexpressionGSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_UP

PIK3CB TBX21 HS3ST1 HSPA1B HSPA2 HSPA8

5.53e-05200876M5994
CoexpressionGSE26488_CTRL_VS_PEPTIDE_INJECTION_HDAC7_DELTAP_TG_OT2_THYMOCYTE_UP

PCSK5 KAT2B PTPRJ PPA1 HS3ST1 HSPA8

5.53e-05200876M8201
CoexpressionCUI_DEVELOPING_HEART_C5_VALVAR_CELL

GLT8D2 HS3ST1 HSPA1A HSPA1B HSPA2 HSPA7

6.34e-05205876M39302
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

PCSK5 SACS PYROXD1 PPP4R2 KCNJ5 MGLL USP48 ZHX1 ZNF654 DMXL1

6.37e-056568710M18979
CoexpressionMURARO_PANCREAS_BETA_CELL

KLHL2 GLT8D2 KAT2B PTPRJ SLC25A4 ACLY IGSF1 USP48 DDX24 HSPA1A HSPA1B HSPA8

6.70e-059468712M39169
CoexpressionDEN_INTERACT_WITH_LCA5

HSPA1A HSPA1B HSPA8

8.69e-0526873M1380
CoexpressionGSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_UP

PPP1R3C NF1 DPY19L1 CCDC93 DMXL1

9.50e-05137875M6346
CoexpressionFERRARI_RESPONSE_TO_FENRETINIDE_DN

PPP1R3C HSPA2

1.08e-045872M1585
CoexpressionFAN_OVARY_CL11_MURAL_GRANULOSA_CELL

SLC25A6 PPP4R2 PPA1 USP48 HS3ST1 HSPA1A HSPA1B HSPA8

1.16e-04444878M41713
ToppCell10x5'-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

ARL5C SCML2 TTC28 SERPINF2 HS3ST1 FHIP1A

1.04e-0617087659cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

ARL5C SCML2 MAPKAPK2 SERPINF2 HS3ST1 FHIP1A

1.08e-0617187672c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A4 SLC25A5 SLC25A6 HSPA1A HSPA2 HSPA8

2.46e-0619787602cc9d39afefa5e5b6f5d93f9adc3a20050b70dd
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK2 ARL5C PTPRJ MAPKAPK2 SSH2

1.97e-05168875c0aef5947b1d7e2c81a7481c509feda1687fcd7f
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK2 ARL5C PTPRJ MAPKAPK2 SSH2

1.97e-05168875c861f80aa12caf54a94d93e38539ff41dc5227a6
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLHL2 PTPRJ SSH2 DENND5A ACY1

2.90e-05182875dc32f8f6a3b13918eb8e93c018f5823d86344080
ToppCellICU-NoSEP-Myeloid-pDC|ICU-NoSEP / Disease, Lineage and Cell Type

ARL5C MAPKAPK2 MGLL SERPINF2 HS3ST1

3.13e-051858757564a47df4a4e3af30d40aa0f48bd9d9c82358ae
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 STIM2 MGLL HSPA1A HSPA1B

3.21e-051868754ae3c0fe8640a8d029875cf3f0f5ffbba38e85f8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 PTPRJ DPY19L1 MGLL FHIP1A

3.47e-051898758c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell(02)_Cycling_Basal_(regeneration)-(1)_24hpi|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint

PPA1 HS3ST1 HSPA1A HSPA1B HSPA8

3.47e-05189875311f3aed469be3c8ff913dcc5a2442daa8446d55
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 PTPRJ DPY19L1 MGLL FHIP1A

3.47e-051898755d902a4660a27548764bf04c6de152b565da835c
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PCSK5 TBX3 SLC25A5 SLC25A6 IGSF1

3.56e-0519087571a00f63fdd4eb4cc6f190d37e7a0417cdaafacb
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-pDC|bone_marrow / Manually curated celltypes from each tissue

MAPKAPK2 MGLL SERPINF2 HS3ST1 FHIP1A

3.56e-05190875dde0e34f6a06cdbbb65c86472360c09f0279a572
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic|bone_marrow / Manually curated celltypes from each tissue

MAPKAPK2 MGLL SERPINF2 HS3ST1 FHIP1A

3.56e-051908756892c603037b61ef88d6ca01b7592dc0d347d63b
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PNPLA8 DENND5A HSPA1A HSPA1B HSPA8

3.83e-05193875dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCellcontrol-pDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SCML2 MAPKAPK2 SERPINF2 HS3ST1 FHIP1A

3.83e-0519387530a6559c9a9e8941861cb259b4836acccc427e68
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK5 TBX3 TTC28 HSPA1A F8

4.12e-05196875cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC25A4 NKX2-1 MGLL PPA1 SERPINF2

4.12e-0519687569f27c2668a9f412b2eb6ca83d11b44863209542
ToppCell(4)_B_cells-(4)_B_follicular|(4)_B_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

GALNTL6 PPA1 HSPA1A HSPA1B HSPA8

4.12e-05196875a38e688c5ce55176504a5d342b5dddafe60589be
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KDM4C VPS13A CHD3 ZFC3H1 DDX24

4.22e-0519787557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell(7)_MNP-(7)_DC_2|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SLC25A5 SLC25A6 PPA1 SERPINF2 HSPA8

4.22e-05197875795e607fb4c102940344b2f4ea7c16e62fd973d3
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC25A5 SLC25A6 HSPA1A HSPA1B HSPA8

4.33e-05198875a1c8e5c332336823c47c04e56b6d7bc8f057c9da
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

NF1 PTPRJ TTC28 KDM4C SSH2

4.43e-0519987594b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellH1299-uninfected|H1299 / Cell line, Condition and Strain

SLC25A6 PRELID3B HSPA1A HSPA1B HSPA8

4.43e-051998754594eb3e6d29285155df8dfd322ccf532d7e94b8
ToppCell18|World / Age, Tissue, Lineage and Cell class

PPP1R3C NKX2-1 HSPA1A HSPA1B HSPA8

4.43e-05199875ef043232ee028778b8ddb92aeed7584e2bf586d5
ToppCellsupra_basal_cell|World / shred by cell class for nasal brushing

SLC25A5 PPA1 HSPA1A HSPA1B HSPA2

4.54e-05200875542bdcec563644e01887fd85eb158b32db439b03
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-C1ql2-Excitatory_Neuron.Slc17a7.C1ql2-Cck_(Dentate_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

VWA3A IGSF1 MYRFL FHIP1A

1.19e-0412987408ecebb7f09d105dfdfd2191fc310910d3baec0f
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Mucinous_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

ARL5C GALNTL6 KDM4C MOAP1

1.59e-04139874898322c0af83038a82fe01da99209d619c5a6156
ToppCelldroplet-Lung-nan-3m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARL5C PTPRJ SERPINF2 MOAP1

1.77e-041438744d11d53330a9197275a8851e1bbf55a113715a09
ToppCelldroplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARL5C PTPRJ SERPINF2 MOAP1

1.77e-041438748b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK2 ARL5C HSPA1A HSPA1B

2.13e-0415087457f21ad380fd1350a2c25d75ad8c3b763ded53ec
ToppCelldroplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARL5C PTPRJ MAPKAPK2 MOAP1

2.13e-04150874b37f538ca5f976b509efe35dc81115b72b227084
ToppCelldroplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARL5C PTPRJ MAPKAPK2 MOAP1

2.13e-041508742c7518918c40e1bf679a2d4e83b472ee6f2f9df8
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Etv1_(Deep_layer_pyramidal_cells-Etv1_typically_marks_layer_5b,_but_some_expression_in_layer_6,_especially_in_medial_regions_like_cingulate)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PAPPA2 RDH5 MOAP1

2.21e-0460873f20230c11a2ca2f66650e53ea6eaa301402294c0
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Etv1_(Deep_layer_pyramidal_cells-Etv1_typically_marks_layer_5b,_but_some_expression_in_layer_6,_especially_in_medial_regions_like_cingulate)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PAPPA2 RDH5 MOAP1

2.21e-046087371e2aa3da41319c72b4eac30e54c65e65e62a3d9
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POLE LPXN UNG CHD3

2.30e-041538745ac4b97d35c1029a5fc625239f92e35136c4d832
ToppCellBAL-Mild-Myeloid-MoAM-MoAM2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGSF1 HS3ST1 HSPA1A HSPA1B

2.30e-041538745fbb90b8477f9fdabf3be19efd3068fbf70abee6
ToppCellBAL-Mild-Myeloid-MoAM-MoAM2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGSF1 HS3ST1 HSPA1A HSPA1B

2.30e-041538742c46183481e6d5a7fa190a743062509465f88e56
ToppCellBAL-Mild-Myeloid-MoAM-MoAM2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGSF1 HS3ST1 HSPA1A HSPA1B

2.30e-04153874decc4f3098a9374a6b65c015a9d36380986290bf
ToppCellBAL-Mild-Myeloid-MoAM-MoAM2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGSF1 HS3ST1 HSPA1A HSPA1B

2.30e-0415387436a28805c0545c2f410c74a6ca0a70d840e75715
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 ARL5C CARD19 LPXN

2.41e-04155874d2e489a08b4e711bd2ed483dcc4da7dbbaa4feea
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 ARL5C CARD19 LPXN

2.41e-04155874cb456d6f13bfb5cb400c0840a0ab6ba4616dcf37
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Myeloid-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 ARL5C CARD19 LPXN

2.41e-04155874a547fdcd974b0813ce6c8cccfec9fff74cac2d1a
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 SACS TBX21 MOAP1

2.54e-04157874071f10d749b590b75a07ab3c7b00956dc7cda4da
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 SACS TBX21 MOAP1

2.54e-04157874af110085dad5d26b0b7068a78f104ba784fa8564
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TBX3 HSPA1A HSPA1B F8

2.60e-04158874de65af8d3b8514b17978155f31975e2347b75251
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-3|TCGA-Skin / Sample_Type by Project: Shred V9

TBX3 TTC28 ZHX1 DMXL1

2.66e-04159874fb222c42f66901852b01cec073ec0732245ee973
ToppCellClub-club-7|World / Class top

DOCK2 GOT1L1 KDM4C

2.67e-0464873df413c5328966480479c41826461c4d817fbe33d
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 ARL5C TBX21 LPXN

2.73e-041608744a0ae0a83a10dbfc13591f4d2228ba8bcd2c2275
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRJ PIK3CB LPXN CHD3

2.73e-041608745d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CARD19 TBX21 LPXN UNG

2.92e-041638749c91415a56b12b3b2d15d253bb59db8bedf49ea2
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CARD19 TBX21 HSPA1A HSPA8

3.21e-04167874c2a0fdb35ec48b956be0686534b29164db6638ab
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

SCML2 MGLL HS3ST1 FHIP1A

3.21e-04167874bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCelldroplet-Heart-nan-18m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LVRN VWA3A MAP3K15 FHIP1A

3.28e-041688742201ae834b53cbdc085f8f02607fa5b5bd911268
ToppCellfacs-Large_Intestine-Proximal|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 TBX3 RDH5 MGLL

3.28e-0416887423e0e1592d7400012d289adb10c7598285bae2e9
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

SCML2 SERPINF2 HS3ST1 FHIP1A

3.28e-04168874968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VWA3A PCSK5 DPY19L1 FHIP1A

3.28e-04168874217770a94ace446cdfc7687b459dece707576e76
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

ARL5C SERPINF2 HS3ST1 FHIP1A

3.28e-04168874dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARL5C PTPRJ MAPKAPK2 MAP3K15

3.28e-0416887400cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VWA3A PCSK5 DPY19L1 FHIP1A

3.35e-041698741c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VWA3A PCSK5 DPY19L1 FHIP1A

3.35e-04169874716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A TBX3 KCNJ5 F8

3.35e-0416987487116c33c5ca8cb1862e103e5607b1df4d264569
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARL5C PTPRJ MAPKAPK2 MAP3K15

3.35e-0416987490c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A4 SLC25A5 SLC25A6 KCNJ5

3.35e-0416987442c31fe94e34f54dbbb5d8b33cedb55badd6232c
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Lymphocytic-mature_NK_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 TBX21 LPXN ZNF654

3.51e-04171874562fc8a422615dbbece67ea49740f0c09bdb9ae3
ToppCell(00)_Basal-(1)_24hpi|(00)_Basal / shred by cell type and Timepoint

POLE UNG HS3ST1 HSPA1B

3.66e-04173874a8e62e7d8baf6af691acd5c50deedbadc119ceba
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 HSPA1B HSPA2 MOAP1

3.66e-041738748bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 HSPA1B HSPA2 MOAP1

3.66e-041738743e3c61468e703330788a10d850ef41a85680f86d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VWA3A DPY19L1 CHD3 FHIP1A

3.66e-0417387495c723b09254ae7131fe5ba0841472502e83269b
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 ARL5C TBX21 LPXN

3.75e-04174874ecee7e012ccd7876fb9df8aa939f8eb05b0c2b13
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 ARL5C TBX21 LPXN

3.75e-04174874693fc31bed0f560644e419fa70ef09f863425416
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VWA3A PCSK5 DPY19L1 FHIP1A

3.75e-041748747d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.6.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CARD19 KCNJ5 HSPA1A HSPA8

3.83e-04175874baaffc9af61f12168d6f7b96eb0b6e98a44a3909
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-31|World / Primary Cells by Cluster

TTC28 DPY19L1 HS3ST1 HSPA1A

3.83e-04175874491508bf9e8a09b057d5711cc23dd91324e6a806
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 MGLL CHD3 HSPA1B

3.91e-04176874d1c4c78a6d4a4ad37912eade4b7d16ef84b9a706
ToppCelldroplet-Kidney-nan-18m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 KCNJ5 POLE F8

3.91e-041768745386386619cf173939d3c117b20e6f27ab397993
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 KCNJ5 POLE F8

3.91e-04176874820edade963768e4bfd86b554da4cd7100567ac8
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 KCNJ5 MGLL F8

3.91e-04176874c4d9166e5bbb7ca544107db14e4374289f5de6bd
ToppCellfacs-Large_Intestine-Proximal-18m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 MGLL CHD3 HSPA1B

3.91e-041768748c2f830124b3bd7c3a483aabe060a1d202c4a409
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 KCNJ5 MGLL F8

3.91e-04176874d58ef51002ea50b3037636038214bbb7454cb503
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VWA3A PCSK5 GOT1L1 FHIP1A

4.00e-0417787462f180d5a487b449f715de49ee1e1e11c4e0cf4d
ToppCellSevere-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

GALNTL6 TBX21 CHD3 DDX24

4.08e-04178874b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCellLPS-antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK2 PTPRJ CARD19 RDH5

4.08e-04178874289d1425c4e57fabcca994b27f9af1c0ce5d5bec
ToppCellfacs-Heart-RA-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIM2 MAPKAPK2 CHD3 ZFC3H1

4.08e-04178874b505e2550860e777535ee95f29c936242fd607f1
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 MGLL HSPA1A HSPA1B

4.17e-04179874fca111789d7354de7ae4cd38253aa0685c0cb2d2
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 MGLL HSPA1A HSPA1B

4.17e-04179874c3e53a3b8e59f7245d737386a1dd0f9d7aa5fb61
ToppCellLPS-IL1RA-Lymphocytic_NKT|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCNX2 DOCK2 TBX21 LPXN

4.17e-041798745ccf0824611ded5c673d94dff3048aedac12f1a8
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 RDH5 MAP3K15 IGSF1

4.26e-04180874729f0d7af573c7796d8e28e6eec3af2fc0bd33a2
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 RDH5 MAP3K15 IGSF1

4.26e-041808749ef79a7c60227e352ac166c7274adb31f585f5ca
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCML2 POLE RDH5 TYW1

4.35e-04181874274c0b768925cd5804483303f8c5ebd17a534c41
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 MGLL HSPA1A HSPA1B

4.44e-04182874506b63a233baf5e3baf924c13c88ab283b6e894f
ToppCellControl-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

KAT2B PPA1 SERPINF2 FHIP1A

4.62e-04184874c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPP1R3C PAPPA2 GLT8D2 TBX3

4.72e-041858747b1c5d99bd7a6e148524029758cee244a17f5d09
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-plasmacytoid_dendritic_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ARL5C MAPKAPK2 SERPINF2 FHIP1A

4.72e-04185874cc5152d3055375172bdf84f442b233c8fbd422b3
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPP1R3C PAPPA2 GLT8D2 TBX3

4.72e-04185874e9033a03d574956cf3ae228740b3166e40a6397f
ToppCellfacs-Heart-RV|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 MGLL HSPA1A HSPA1B

4.72e-041858747cf2b0db059605032bfae60cf1b93c4c62608f0c
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPP1R3C PAPPA2 GLT8D2 TBX3

4.72e-04185874578f12c6b2e33d09598dc8e022a20c8555d1325c
ToppCellEndothelial-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

TBX3 HSPA1A HSPA1B F8

4.82e-04186874796cbae2a417502aaf0891fc9c382bbfd88967fe
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 RDH5 MAP3K15 IGSF1

4.82e-04186874d4e327cc1d7b618654ffe0ff6475fe8e8cc5cb01
ToppCellPrimary_Motor_Cortex_(M1)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC25A5 PPA1 HSPA1B HSPA8

4.91e-04187874892a4d439a0aa90f254dd17e1edce1fdc3619510
DrugClodronate

SLC25A4 SLC25A5 SLC25A6

5.39e-083873DB00720
Drugdehydroabietylamine

SLC25A4 SLC25A5 SLC25A6

2.15e-074873ctd:C000600819
Drugbeta-hydroxypalmitoyl-CoA

SLC25A4 SLC25A5 SLC25A6 ACLY

4.56e-0717874CID000440600
Drugclosantel

SLC25A4 SLC25A5 SLC25A6

1.87e-067873ctd:C023342
DrugAcetyl Coenzyme A

KAT2B ERCC6 ACLY

6.34e-0610873ctd:D000105
DrugAC1L4X2K

SLC25A4 SLC25A5 SLC25A6

6.34e-0610873CID000193824
Drug1,5-dihydroxy-3-methylanthraquinone

ARSL GUSB

1.44e-052872CID005316800
DrugThioguanine (usan

SLC25A4 SLC25A5 SLC25A6 UNG MGLL

1.77e-0584875CID005473385
Drugoleoylcarnitine

SLC25A4 SLC25A5 SLC25A6

2.91e-0516873CID006441392
Diseaseautosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 (implicated_via_orthology)

SLC25A4 SLC25A5 SLC25A6

8.26e-084823DOID:0111517 (implicated_via_orthology)
Diseasegraft-versus-host disease (biomarker_via_orthology)

HSPA1A HSPA1B HSPA8

2.06e-075823DOID:0081267 (biomarker_via_orthology)
Diseasehypertrophic cardiomyopathy (implicated_via_orthology)

STIM2 SLC25A4 SLC25A5 SLC25A6

1.25e-0629824DOID:11984 (implicated_via_orthology)
Diseasehearing threshold measurement

GALNTL6 SGSM1 GID4

6.44e-0528823EFO_0007618
Diseasechoreatic disease (is_implicated_in)

NKX2-1 VPS13A

7.59e-055822DOID:12859 (is_implicated_in)
Diseasemitochondrial metabolism disease (implicated_via_orthology)

SLC25A4 SLC25A5 SLC25A6

1.27e-0435823DOID:700 (implicated_via_orthology)
DiseaseMajor depression, single episode

HSPA1A HSPA1B

2.71e-049822C0024517
DiseaseCongenital Hypothyroidism

NKX2-1 IGSF1

5.83e-0413822C0010308
DiseasePROSTATE CANCER, HEREDITARY, 1

DOCK2 TTC28 CHD3

6.31e-0460823C4722327
DiseaseProstate cancer, familial

DOCK2 TTC28 CHD3

9.50e-0469823C2931456
Diseasecolorectal cancer (is_marker_for)

TBX3 ERCC6 PIK3CB HSPA8

9.77e-04157824DOID:9256 (is_marker_for)
Diseasestem Cell Growth Factor beta measurement

PCSK5 GLT8D2 KDM4C

1.21e-0375823EFO_0008292
Diseasediet measurement, HOMA-B

PCNX2 RAB11FIP2

1.27e-0319822EFO_0004469, EFO_0008111
Diseaseschizophrenia (is_implicated_in)

NCSTN HSPA1A HSPA1B

1.35e-0378823DOID:5419 (is_implicated_in)
Diseasemortality

GALNTL6 TTC28 SLC25A4 VPS13A

1.40e-03173824EFO_0004352
DiseaseCarcinoma, Pancreatic Ductal

HSPA1A HSPA1B

2.02e-0324822C0887833
Diseaselung squamous cell carcinoma (is_implicated_in)

PTPRJ POLE

2.02e-0324822DOID:3907 (is_implicated_in)
Diseasealcohol use disorder (implicated_via_orthology)

PPP1R3C KDM4C PIK3CB SSH2

2.16e-03195824DOID:1574 (implicated_via_orthology)
Diseasecomplement C4b measurement

HSPA1A HSPA1B

2.20e-0325822EFO_0008092
Diseaselow affinity immunoglobulin gamma Fc region receptor II-b measurement

NCSTN HSPA7

2.20e-0325822EFO_0021970
Diseasemacular degeneration (is_marker_for)

ERCC6 HSPA8

2.37e-0326822DOID:4448 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
PHQVFTWTQMCDIKD

UNG

131

P13051
KNTHIVVSWMIAQTV

SLC25A6

206

P12236
QWATQVFQKPHEVVM

COG7

266

P83436
NVEEIILPKTHFFMW

ARL5C

51

A6NH57
RGTMWKVHFVTPVFQ

ARSL

471

P51690
MSFVVLVPTHFEWNV

SERPINF2

296

P08697
MTNEGHPWVSLVVQK

GOT1L1

41

Q8NHS2
KNTHIVISWMIAQTV

SLC25A5

206

P05141
APPFVVLNMQHWKSE

C14orf28

221

Q4W4Y0
VWLDQSSKVFPEMQV

LVRN

626

Q6Q4G3
IVAHPLNEKMWSAVF

DMXL1

2346

Q9Y485
IVCPTTVMHQWVKEF

ERCC6

571

Q03468
SMIHLTPTQVKIWFQ

NKX2-1

196

P43699
LWMHTDPVSQKNESV

NCSTN

376

Q92542
ISHEINQKSPFWEMS

KCNJ5

276

P48544
KMENEKTITVVHQPW

PTPRJ

156

Q12913
ITEFMNHPWIMQSTK

MAPKAPK2

316

P49137
RQKTHVPMLQVWTAD

NCBP1

206

Q09161
PEVTNSVFHEINMWV

MGLL

276

Q99685
LQQVKSHQSAWPFME

KAT2B

736

Q92831
DATVQSDMKHWPFRV

HSPA2

81

P54652
PVVQSDMKHWPFQVI

HSPA1B

81

P0DMV9
FHTTQMIKAWQVPDV

MOAP1

186

Q96BY2
VCFSAVKEPWSMQHI

PCNX2

1016

A6NKB5
HSFISMEPKVEWIQQ

PCSK5

91

Q92824
IISDMWGVLAKQQTH

DPY19L1

426

Q2PZI1
HIQVWGSPKFVETEM

MYRFL

271

Q96LU7
NKWAHVMCAVAVPEV

KDM4C

771

Q9H3R0
KVLTAMNQTWHPEHF

LPXN

221

O60711
FNPGVIVANMTEWKH

GLT8D2

226

Q9H1C3
WFAHRTPMPKIQNVS

F8

791

P00451
RWFEHVQETKPTIMV

POLE

346

Q07864
ADTTVQSDMKHWPFQ

HSPA7

81

P48741
VFMRWKEQFLVPDHT

GID4

231

Q8IVV7
VSPVKWEQTMHAIYE

MCAT

321

Q8IVS2
TADTLEHWMEPVKVQ

PAPPA2

1696

Q9BXP8
EHWMEPVKVQSIVCT

PAPPA2

1701

Q9BXP8
SQQHAKVVPWMRKTE

PAF1

121

Q8N7H5
MDFIHIFPVVQWLVK

CCDC93

111

Q567U6
DPETCMIVFKNHWAQ

FHIP1A

21

Q05DH4
QMTWIRPSHKTFQVS

IGSF1

76

Q8N6C5
WFEVVHMSQTTISPL

DOCK2

1481

Q92608
KVQEFEHINGRWSMP

CHD3

1501

Q12873
RDKNHPAVVMWSVAN

GUSB

436

P08236
LWVPQMHKQASAFVD

REXO1L1P

136

Q8IX06
VWQAQAVQMLVSVSH

CARD19

161

Q96LW7
ATWFVVQLTMSPEVH

CRHR1

196

P34998
ETITALMFPFQWQHV

DENND5A

326

Q6IQ26
KDVFHMVVEVPRWSN

PPA1

41

Q15181
AFAIPMIHAVLQWQK

DDX24

246

Q9GZR7
EEVDVFTAPHWRMKQ

FBXL5

6

Q9UKA1
PVVQSDMKHWPFQVI

HSPA1A

81

P0DMV8
KPKNHVTFMTSWVEF

SACS

3571

Q9NZJ4
HVAKTGETMIQWSQF

PPP4R2

31

Q9NY27
AVVQSDMKHWPFMVV

HSPA8

81

P11142
QMPFSWPHQLTVEKT

HS3ST1

106

O14792
VSPTEMKQMHEWNFT

MAP3K15

561

Q6ZN16
QNVIVGTVKMSWSHA

PNPLA8

516

Q9NP80
QWIFEHINMTVLEKF

GALNTL6

581

Q49A17
NMKWVQFSNLHVDVP

MRPS10

41

P82664
DHPWETVTTAAMQKY

PRELID3B

11

Q9Y3B1
PATGEQWMSKVVTFH

TBX3

191

O15119
IVHVQWKPDGVQTQM

PPP1R3C

256

Q9UQK1
AGKVHYPVAWVNTMV

PIK3CB

431

P42338
MIWAQKTNTPADVFI

RO60

451

P10155
PQSVQQAAKWVEMHV

RDH5

86

Q92781
HTKAIVWGMQTRAVQ

ACLY

496

P53396
KNVHIFVSWMIAQSV

SLC25A4

206

P12235
VTLEFAQKWMHPQVT

ACY1

301

Q03154
TLHQMVVFTKEVNEW

TPTE

311

P56180
QTVVAFHSPYWMVNK

VPS13A

2206

Q96RL7
DMTSSQWFKTQHVQP

RNASE8

31

Q8TDE3
VHIFKPVSVQAMWSA

SSH2

166

Q76I76
HKSVTADTEMWPVYV

PYROXD1

286

Q8WU10
WSVDEVIQFMKHTDP

SCML2

631

Q9UQR0
PHNWMKDFILTVSIV

STIM2

211

Q9P246
QLHMLKSAFVRTQWP

ZHX1

671

Q9UKY1
HPTDLNVRQTVMKWS

ZNF654

771

Q8IZM8
MAAHRPVEWVQAVVS

NF1

1

P21359
MMLSEQAQKWFPTHV

RAB11FIP2

1

Q7L804
HQTADVMTLKWTPNQ

SGSM1

281

Q2NKQ1
KQHVYEVESPQWEIM

ZNF582

91

Q96NG8
AVHNLKMFWQSTPQH

TTC28

2356

Q96AY4
LTMAHVPWHEEVVQF

TYW1

616

Q9NV66
PSEWQMIQKLFVVDH

USP48

801

Q86UV5
TESFVMPWQAVQDVK

ZFC3H1

1556

O60293
LWSKFNQHQTEMIIT

TBX21

146

Q9UL17
VSSTIHEKAMIQFEW

VWA3A

446

A6NCI4
NIKSNEWFHVAPMNT

KLHL2

421

O95198