Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessembryonic digit morphogenesis

PRICKLE1 GLI2 GLI3 FBXW4 HDAC1

4.21e-0674675GO:0042733
GeneOntologyBiologicalProcessUTP biosynthetic process

CAD NME2P1 NME2

5.31e-0611673GO:0006228
GeneOntologyBiologicalProcessUTP metabolic process

CAD NME2P1 NME2

9.15e-0613673GO:0046051
GeneOntologyBiologicalProcessnegative regulation of smoothened signaling pathway

RACK1 ENPP1 GLI2 GLI3

1.04e-0542674GO:0045879
GeneOntologyBiologicalProcessnegative regulation of complement activation

SUSD4 VSIG4 CD46

1.16e-0514673GO:0045916
GeneOntologyBiologicalProcesspyrimidine ribonucleoside triphosphate biosynthetic process

CAD NME2P1 NME2

1.78e-0516673GO:0009209
GeneOntologyBiologicalProcessappendage morphogenesis

PRICKLE1 ENPP1 GLI2 GLI3 FBXW4 HDAC1

3.04e-05185676GO:0035107
GeneOntologyBiologicalProcesslimb morphogenesis

PRICKLE1 ENPP1 GLI2 GLI3 FBXW4 HDAC1

3.04e-05185676GO:0035108
GeneOntologyBiologicalProcesspyrimidine ribonucleoside triphosphate metabolic process

CAD NME2P1 NME2

3.06e-0519673GO:0009208
GeneOntologyBiologicalProcessnegative regulation of humoral immune response

SUSD4 VSIG4 CD46

3.06e-0519673GO:0002921
GeneOntologyBiologicalProcesssmoothened signaling pathway involved in ventral spinal cord interneuron specification

GLI2 GLI3

3.11e-053672GO:0021775
GeneOntologyBiologicalProcesssmoothened signaling pathway involved in spinal cord motor neuron cell fate specification

GLI2 GLI3

3.11e-053672GO:0021776
GeneOntologyBiologicalProcesssmoothened signaling pathway involved in ventral spinal cord patterning

GLI2 GLI3

3.11e-053672GO:0021910
GeneOntologyBiologicalProcessnegative regulation of complement activation, alternative pathway

SUSD4 VSIG4

3.11e-053672GO:0045957
GeneOntologyBiologicalProcesspyrimidine nucleoside triphosphate biosynthetic process

CAD NME2P1 NME2

3.59e-0520673GO:0009148
GeneOntologyBiologicalProcessproteasome-mediated ubiquitin-dependent protein catabolic process

RACK1 PRICKLE1 MTM1 FBXW4 UBR3 RNF216 KEAP1 TBL1X

6.74e-05424678GO:0043161
GeneOntologyBiologicalProcesspyrimidine ribonucleotide biosynthetic process

CAD NME2P1 NME2

7.16e-0525673GO:0009220
GeneOntologyBiologicalProcesspyrimidine nucleoside triphosphate metabolic process

CAD NME2P1 NME2

7.16e-0525673GO:0009147
GeneOntologyBiologicalProcesslimb development

PRICKLE1 ENPP1 GLI2 GLI3 FBXW4 HDAC1

8.81e-05224676GO:0060173
GeneOntologyBiologicalProcessappendage development

PRICKLE1 ENPP1 GLI2 GLI3 FBXW4 HDAC1

8.81e-05224676GO:0048736
GeneOntologyBiologicalProcessregulation of complement activation

SUSD4 VSIG4 CD46

9.06e-0527673GO:0030449
GeneOntologyBiologicalProcesspositive regulation of cell population proliferation

NAMPT RASAL3 GLI2 GLI3 PKHD1 FBXW4 RICTOR CD46 ITGA2 NME2 MEGF10 HDAC1 ZNF304

1.01e-0411906713GO:0008284
GeneOntologyBiologicalProcessprotein retention in Golgi apparatus

VPS13C VPS13A

1.03e-045672GO:0045053
GeneOntologyBiologicalProcessregulation of cell-cell adhesion

RAG1 RASAL3 HLA-DOA GLI2 GLI3 VSIG4 PKHD1 CD46 MEGF10

1.03e-04580679GO:0022407
GeneOntologyBiologicalProcessembryonic limb morphogenesis

PRICKLE1 GLI2 GLI3 FBXW4 HDAC1

1.20e-04148675GO:0030326
GeneOntologyBiologicalProcessembryonic appendage morphogenesis

PRICKLE1 GLI2 GLI3 FBXW4 HDAC1

1.20e-04148675GO:0035113
GeneOntologyBiologicalProcesspyrimidine nucleotide biosynthetic process

CAD NME2P1 NME2

1.67e-0433673GO:0006221
GeneOntologyBiologicalProcesspyrimidine ribonucleotide metabolic process

CAD NME2P1 NME2

1.82e-0434673GO:0009218
GeneOntologyBiologicalProcessmammary gland development

CAD GLI2 GLI3 ITGA2 CSMD1

1.83e-04162675GO:0030879
GeneOntologyBiologicalProcessheterochromatin formation

BAZ2A CBX3 CDYL HDAC1 ZNF304

1.89e-04163675GO:0031507
GeneOntologyBiologicalProcessregulation of complement activation, alternative pathway

SUSD4 VSIG4

2.16e-047672GO:0030451
GeneOntologyBiologicalProcesssmoothened signaling pathway involved in dorsal/ventral neural tube patterning

GLI2 GLI3

2.16e-047672GO:0060831
GeneOntologyBiologicalProcessleukocyte differentiation

RAG1 HLA-DOA ENPP1 GLI2 GLI3 PAFAH1B1 VPS13A CD46 NME2 LRRC17

2.18e-047896710GO:0002521
GeneOntologyBiologicalProcessWnt signaling pathway

RACK1 PRICKLE1 ENPP1 GLI3 FBXW4 FRMD8P1 HDAC1 TBL1X

2.59e-04516678GO:0016055
GeneOntologyBiologicalProcesspositive regulation of cell-cell adhesion

RAG1 RASAL3 HLA-DOA GLI2 GLI3 CD46 MEGF10

2.64e-04389677GO:0022409
GeneOntologyBiologicalProcessestablishment of cell polarity

RACK1 PRICKLE1 PAFAH1B1 PKHD1 RICTOR

2.76e-04177675GO:0030010
GeneOntologyBiologicalProcesscell fate specification involved in pattern specification

GLI2 GLI3

2.87e-048672GO:0060573
GeneOntologyBiologicalProcessnegative regulation of complement activation, classical pathway

SUSD4 CD46

2.87e-048672GO:0045959
GeneOntologyBiologicalProcessventral spinal cord interneuron specification

GLI2 GLI3

2.87e-048672GO:0021521
GeneOntologyBiologicalProcesspositive regulation of T cell activation

RAG1 RASAL3 HLA-DOA GLI2 GLI3 CD46

3.57e-04290676GO:0050870
GeneOntologyBiologicalProcesspyrimidine-containing compound biosynthetic process

CAD NME2P1 NME2

3.68e-0443673GO:0072528
GeneOntologyBiologicalProcessmaintenance of postsynaptic density structure

PRICKLE1 CSMD2

3.69e-049672GO:0099562
GeneOntologyBiologicalProcesshindgut morphogenesis

GLI2 GLI3

3.69e-049672GO:0007442
GeneOntologyBiologicalProcessregulation of smoothened signaling pathway

RACK1 ENPP1 GLI2 GLI3

3.80e-04105674GO:0008589
GeneOntologyBiologicalProcessDNA methylation-dependent constitutive heterochromatin formation

BAZ2A HDAC1 ZNF304

3.94e-0444673GO:0006346
GeneOntologyBiologicalProcessnegative regulation of Wnt signaling pathway

RACK1 PRICKLE1 GLI3 FRMD8P1 HDAC1

4.31e-04195675GO:0030178
GeneOntologyBiologicalProcessestablishment of centrosome localization

PAFAH1B1 PKHD1

4.60e-0410672GO:0051660
GeneOntologyBiologicalProcesshindgut development

GLI2 GLI3

4.60e-0410672GO:0061525
GeneOntologyBiologicalProcessregulation of complement activation, classical pathway

SUSD4 CD46

4.60e-0410672GO:0030450
GeneOntologyBiologicalProcessregulation of leukocyte differentiation

RAG1 HLA-DOA GLI2 GLI3 CD46 NME2 LRRC17

4.76e-04429677GO:1902105
GeneOntologyBiologicalProcessproteasomal protein catabolic process

RACK1 PRICKLE1 MTM1 FBXW4 UBR3 RNF216 KEAP1 TBL1X

4.86e-04567678GO:0010498
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

ZNF487 PRICKLE1 BAZ2A GLI2 GLI3 CHD5 ZMYM2 CBX3 CDYL HDAC1 TBL1X ZNF572 ZNF304

4.93e-0413996713GO:0045892
GeneOntologyBiologicalProcessnegative regulation of gene expression, epigenetic

BAZ2A CBX3 CDYL HDAC1 ZNF304

5.18e-04203675GO:0045814
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

ZNF487 PRICKLE1 BAZ2A GLI2 GLI3 CHD5 ZMYM2 CBX3 CDYL HDAC1 TBL1X ZNF572 ZNF304

5.41e-0414136713GO:1902679
GeneOntologyBiologicalProcesspositive regulation of cell adhesion

RAG1 RASAL3 HLA-DOA GLI2 GLI3 CD46 ITGA2 MEGF10

5.58e-04579678GO:0045785
GeneOntologyBiologicalProcessspinal cord motor neuron cell fate specification

GLI2 GLI3

5.61e-0411672GO:0021520
GeneOntologyBiologicalProcesspositive regulation of leukocyte cell-cell adhesion

RAG1 RASAL3 HLA-DOA GLI2 GLI3 CD46

5.71e-04317676GO:1903039
GeneOntologyBiologicalProcessregulation of leukocyte cell-cell adhesion

RAG1 RASAL3 HLA-DOA GLI2 GLI3 VSIG4 CD46

6.07e-04447677GO:1903037
GeneOntologyBiologicalProcessembryo development

RACK1 PRICKLE1 ENPP1 GLI2 GLI3 PAFAH1B1 FBXW4 UBR3 RICTOR KEAP1 TDRD6 CUBN HDAC1

6.35e-0414376713GO:0009790
GeneOntologyBiologicalProcesscell-cell adhesion

RAG1 RASAL3 PRICKLE1 HLA-DOA GLI2 GLI3 VSIG4 PKHD1 CD46 ITGA2 MEGF10

6.52e-0410776711GO:0098609
GeneOntologyBiologicalProcessventral spinal cord interneuron fate commitment

GLI2 GLI3

6.72e-0412672GO:0060579
GeneOntologyBiologicalProcesscell fate commitment involved in pattern specification

GLI2 GLI3

6.72e-0412672GO:0060581
GeneOntologyBiologicalProcessnegative regulation of humoral immune response mediated by circulating immunoglobulin

SUSD4 CD46

6.72e-0412672GO:0002924
GeneOntologyBiologicalProcessregulation of T cell activation

RAG1 RASAL3 HLA-DOA GLI2 GLI3 VSIG4 CD46

7.01e-04458677GO:0050863
GeneOntologyBiologicalProcesspyrimidine nucleotide metabolic process

CAD NME2P1 NME2

7.62e-0455673GO:0006220
GeneOntologyBiologicalProcessfacultative heterochromatin formation

BAZ2A HDAC1 ZNF304

7.62e-0455673GO:0140718
GeneOntologyBiologicalProcessregulation of cell adhesion

RAG1 RASAL3 HLA-DOA GLI2 GLI3 VSIG4 PKHD1 CD46 ITGA2 MEGF10

7.75e-049276710GO:0030155
GeneOntologyBiologicalProcessGTP biosynthetic process

NME2P1 NME2

7.92e-0413672GO:0006183
GeneOntologyBiologicalProcessregulation of T cell differentiation

RAG1 HLA-DOA GLI2 GLI3 CD46

8.40e-04226675GO:0045580
GeneOntologyBiologicalProcessventral spinal cord interneuron differentiation

GLI2 GLI3

9.22e-0414672GO:0021514
GeneOntologyBiologicalProcessnegative regulation of immune system process

PIK3AP1 SUSD4 HLA-DOA GLI3 VSIG4 CD46 NME2 LRRC17

9.77e-04631678GO:0002683
GeneOntologyBiologicalProcessregulation of humoral immune response

SUSD4 VSIG4 CD46

9.82e-0460673GO:0002920
GeneOntologyBiologicalProcessleukocyte cell-cell adhesion

RAG1 RASAL3 HLA-DOA GLI2 GLI3 VSIG4 CD46

9.92e-04486677GO:0007159
GeneOntologyBiologicalProcessCTP biosynthetic process

NME2P1 NME2

1.06e-0315672GO:0006241
GeneOntologyBiologicalProcessubiquitin-dependent protein catabolic process

RACK1 PRICKLE1 MTM1 FBXW4 UBR3 RNF216 KEAP1 TBL1X

1.07e-03640678GO:0006511
GeneOntologyBiologicalProcessregulation of proteasomal ubiquitin-dependent protein catabolic process

RACK1 PRICKLE1 MTM1 KEAP1

1.09e-03139674GO:0032434
GeneOntologyBiologicalProcessmodification-dependent protein catabolic process

RACK1 PRICKLE1 MTM1 FBXW4 UBR3 RNF216 KEAP1 TBL1X

1.19e-03651678GO:0019941
GeneOntologyBiologicalProcesseyelid development in camera-type eye

PRICKLE1 HDAC1

1.21e-0316672GO:0061029
GeneOntologyBiologicalProcessnegative regulation of B cell mediated immunity

SUSD4 CD46

1.21e-0316672GO:0002713
GeneOntologyBiologicalProcessnegative regulation of immunoglobulin mediated immune response

SUSD4 CD46

1.21e-0316672GO:0002890
GeneOntologyBiologicalProcessregulation of Wnt signaling pathway

RACK1 PRICKLE1 GLI3 FRMD8P1 HDAC1 TBL1X

1.24e-03368676GO:0030111
GeneOntologyBiologicalProcessmammary gland morphogenesis

GLI2 GLI3 CSMD1

1.24e-0365673GO:0060443
GeneOntologyBiologicalProcesspositive regulation of T cell differentiation

RAG1 GLI2 GLI3 CD46

1.24e-03144674GO:0045582
GeneOntologyBiologicalProcessmodification-dependent macromolecule catabolic process

RACK1 PRICKLE1 MTM1 FBXW4 UBR3 RNF216 KEAP1 TBL1X

1.25e-03656678GO:0043632
GeneOntologyBiologicalProcesslayer formation in cerebral cortex

GLI3 PAFAH1B1

1.37e-0317672GO:0021819
GeneOntologyBiologicalProcessmaintenance of postsynaptic specialization structure

PRICKLE1 CSMD2

1.37e-0317672GO:0098880
GeneOntologyBiologicalProcessCTP metabolic process

NME2P1 NME2

1.37e-0317672GO:0046036
GeneOntologyBiologicalProcessodontogenesis

ENPP1 GLI2 GLI3 HDAC1

1.48e-03151674GO:0042476
GeneOntologyBiologicalProcessestablishment or maintenance of cell polarity

RACK1 PRICKLE1 PAFAH1B1 PKHD1 RICTOR

1.49e-03257675GO:0007163
GeneOntologyBiologicalProcessT cell differentiation

RAG1 HLA-DOA ENPP1 GLI2 GLI3 CD46

1.50e-03382676GO:0030217
GeneOntologyBiologicalProcesscomplement activation

SUSD4 VSIG4 CD46

1.54e-0370673GO:0006956
GeneOntologyBiologicalProcessGolgi to endosome transport

VPS13C VPS13A

1.54e-0318672GO:0006895
GeneOntologyBiologicalProcessmicroglia differentiation

ENPP1 VPS13A

1.54e-0318672GO:0014004
GeneOntologyBiologicalProcesscollagen-activated signaling pathway

ENPP1 ITGA2

1.54e-0318672GO:0038065
GeneOntologyBiologicalProcesspositive regulation of lymphocyte activation

RAG1 RASAL3 HLA-DOA GLI2 GLI3 CD46

1.56e-03385676GO:0051251
GeneOntologyBiologicalProcessnegative regulation of canonical Wnt signaling pathway

PRICKLE1 GLI3 FRMD8P1 HDAC1

1.59e-03154674GO:0090090
GeneOntologyBiologicalProcessbone development

ENPP1 GLI3 PAFAH1B1 FREM1 LRRC17

1.67e-03264675GO:0060348
GeneOntologyBiologicalProcesscomplement activation, alternative pathway

SUSD4 VSIG4

1.72e-0319672GO:0006957
GeneOntologyBiologicalProcesspyrimidine nucleoside monophosphate biosynthetic process

CAD NME2

1.72e-0319672GO:0009130
GeneOntologyBiologicalProcessregulation of lymphocyte differentiation

RAG1 HLA-DOA GLI2 GLI3 CD46

1.73e-03266675GO:0045619
GeneOntologyCellularComponentGLI-SUFU complex

GLI2 GLI3

6.23e-054682GO:1990788
GeneOntologyCellularComponentCul3-RING ubiquitin ligase complex

KLHL7 GAN KEAP1

2.77e-0439683GO:0031463
GeneOntologyCellularComponentheterochromatin

BAZ2A CHD5 CBX3 HDAC1

3.30e-04101684GO:0000792
DomainSushi

SUSD4 CD46 CSMD1 CSMD2 CSMD3

1.00e-0652655PF00084
DomainCCP

SUSD4 CD46 CSMD1 CSMD2 CSMD3

1.21e-0654655SM00032
DomainSUSHI

SUSD4 CD46 CSMD1 CSMD2 CSMD3

1.45e-0656655PS50923
DomainSushi_SCR_CCP_dom

SUSD4 CD46 CSMD1 CSMD2 CSMD3

1.59e-0657655IPR000436
DomainCUB

CUBN CSMD1 CSMD2 CSMD3

2.52e-0549654PF00431
DomainCUB

CUBN CSMD1 CSMD2 CSMD3

2.73e-0550654SM00042
Domain-

CUBN CSMD1 CSMD2 CSMD3

3.19e-05526542.60.120.290
DomainCUB

CUBN CSMD1 CSMD2 CSMD3

3.44e-0553654PS01180
DomainVPS13

VPS13C VPS13A

3.57e-053652IPR026847
DomainVPS13_mid_rpt

VPS13C VPS13A

3.57e-053652PF16910
DomainVPS13

VPS13C VPS13A

3.57e-053652PF16908
DomainVPS13_N2

VPS13C VPS13A

3.57e-053652IPR031646
DomainVPS13_mid_rpt

VPS13C VPS13A

3.57e-053652IPR031642
DomainCUB_dom

CUBN CSMD1 CSMD2 CSMD3

4.59e-0557654IPR000859
DomainVPS13_C

VPS13C VPS13A

7.12e-054652PF16909
DomainSHR-BD

VPS13C VPS13A

7.12e-054652IPR009543
DomainVPS13_C

VPS13C VPS13A

7.12e-054652IPR031645
DomainSHR-BD

VPS13C VPS13A

7.12e-054652PF06650
DomainChromo_domain

CHD5 CBX3 CDYL

7.73e-0524653IPR023780
DomainChromo

CHD5 CBX3 CDYL

9.88e-0526653PF00385
DomainATG_C

VPS13C VPS13A

1.18e-045652PF09333
DomainAutophagy-rel_C

VPS13C VPS13A

1.18e-045652IPR015412
DomainCHROMO_1

CHD5 CBX3 CDYL

1.24e-0428653PS00598
DomainCHROMO_2

CHD5 CBX3 CDYL

1.24e-0428653PS50013
DomainChromodomain-like

CHD5 CBX3 CDYL

1.86e-0432653IPR016197
DomainChromo/shadow_dom

CHD5 CBX3 CDYL

2.04e-0433653IPR000953
DomainCHROMO

CHD5 CBX3 CDYL

2.04e-0433653SM00298
DomainVPS13_N

VPS13C VPS13A

3.29e-048652IPR026854
DomainChorein_N

VPS13C VPS13A

3.29e-048652PF12624
DomainNDP_KINASES

NME2P1 NME2

4.23e-049652PS00469
DomainLisH

PAFAH1B1 TBL1X

4.23e-049652PF08513
DomainBTB-kelch_protein

KLHL7 GAN KEAP1

4.49e-0443653IPR017096
DomainNDK

NME2P1 NME2

5.27e-0410652SM00562
DomainInterfer-bind

IL10RB IL20RA

5.27e-0410652PF09294
DomainNDK

NME2P1 NME2

5.27e-0410652PF00334
DomainInterferon/interleukin_rcp_dom

IL10RB IL20RA

5.27e-0410652IPR015373
DomainNucleoside_diP_kinase

NME2P1 NME2

7.70e-0412652IPR001564
DomainTissue_fac

IL10RB IL20RA

7.70e-0412652PF01108
DomainTissue_factor

IL10RB IL20RA

7.70e-0412652IPR001187
DomainKelch-typ_b-propeller

KLHL7 GAN KEAP1

9.28e-0455653IPR015915
DomainKelch

KLHL7 GAN KEAP1

1.08e-0358653SM00612
DomainBACK

KLHL7 GAN KEAP1

1.19e-0360653SM00875
DomainBACK

KLHL7 GAN KEAP1

1.25e-0361653PF07707
DomainBACK

KLHL7 GAN KEAP1

1.25e-0361653IPR011705
DomainChromodomain_CS

CBX3 CDYL

1.76e-0318652IPR023779
DomainKelch_1

KLHL7 GAN KEAP1

1.86e-0370653PF01344
DomainKelch_1

KLHL7 GAN KEAP1

1.86e-0370653IPR006652
DomainWD40

RACK1 PAFAH1B1 FBXW4 ELP2 TBL1X

2.07e-03259655PF00400
DomainWD40

RACK1 PAFAH1B1 FBXW4 ELP2 TBL1X

2.40e-03268655SM00320
DomainWD40_repeat

RACK1 PAFAH1B1 FBXW4 ELP2 TBL1X

2.56e-03272655IPR001680
DomainWD_REPEATS_1

RACK1 PAFAH1B1 FBXW4 ELP2 TBL1X

2.81e-03278655PS00678
DomainWD_REPEATS_2

RACK1 PAFAH1B1 FBXW4 ELP2 TBL1X

2.85e-03279655PS50082
DomainWD_REPEATS_REGION

RACK1 PAFAH1B1 FBXW4 ELP2 TBL1X

2.85e-03279655PS50294
DomainG-protein_beta_WD-40_rep

RACK1 PAFAH1B1 TBL1X

3.24e-0385653IPR020472
DomainWD40_repeat_dom

RACK1 PAFAH1B1 FBXW4 ELP2 TBL1X

3.73e-03297655IPR017986
DomainLisH

PAFAH1B1 TBL1X

4.25e-0328652SM00667
Pubmed

Identification of two new members of the CSMD gene family.

CSMD1 CSMD2 CSMD3

7.15e-09368312906867
Pubmed

Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3.

GLI2 GLI3 HDAC1

2.49e-07768312435627
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

ZNF592 BAZ2A ZMYM2 CBX3 CDYL HDAC1

5.11e-0715068628242625
Pubmed

Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico.

CAD GLI2 ITGA2 FREM1

1.04e-063968425859222
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZNF592 ZMIZ2 ZMYM2 CBX3 KEAP1 NME2 HDAC1 TBL1X

1.60e-0641868834709266
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

ZNF592 BAZ2A CHD5 ZMYM2 HDAC1

1.86e-0610368532744500
Pubmed

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.

ZMYM2 CDYL HDAC1 TBL1X

1.87e-064568421258344
Pubmed

Characterization of the human nm23-H2 promoter region and localization of the microsatellite D17S396.

NME2P1 NME2

3.77e-0626827488060
Pubmed

A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome.

GLI2 GLI3

3.77e-06268217283082
Pubmed

New mouse models of congenital anorectal malformations.

GLI2 GLI3

3.77e-06268210693670
Pubmed

Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.

CSMD1 CSMD2

3.77e-06268224408017
Pubmed

Differential effects of GLI2 and GLI3 in regulating cervical cancer malignancy in vitro and in vivo.

GLI2 GLI3

3.77e-06268229967343
Pubmed

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.

GLI2 GLI3

3.77e-06268220154143
Pubmed

Novel functional features of the Lis-H domain: role in protein dimerization, half-life and cellular localization.

PAFAH1B1 TBL1X

3.77e-06268216258276
Pubmed

Normal exon copy number of the GLI2 and GLI3 genes in patients with esophageal atresia.

GLI2 GLI3

3.77e-06268223442119
Pubmed

Brain-specific transcript variants of 5' and 3' ends of mouse VPS13A and VPS13C.

VPS13C VPS13A

3.77e-06268217196930
Pubmed

A genetic association study of CSMD1 and CSMD2 with cognitive function.

CSMD1 CSMD2

3.77e-06268227890662
Pubmed

The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia.

CSMD1 CSMD2

3.77e-06268221439553
Pubmed

Adult Gli2+/-;Gli3Δ699/+ Male and Female Mice Display a Spectrum of Genital Malformation.

GLI2 GLI3

3.77e-06268227814383
Pubmed

A study on etiology of incontinence in double knockout mouse model.

GLI2 GLI3

3.77e-06268236272934
Pubmed

Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

ZMIZ2 CSMD1 CSMD2 CSMD3

7.30e-066368411572484
Pubmed

Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.

GLI2 GLI3 CD46

7.96e-062068323326517
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

RASAL3 RACK1 ZNF592 BAZ2A GLI3 CHD5 CBX3 RICTOR KEAP1 CSMD1 HDAC1

1.02e-051116681131753913
Pubmed

Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia.

GLI2 GLI3 PKHD1

1.07e-052268328432216
Pubmed

A three-gene expression signature model for risk stratification of patients with neuroblastoma.

CHD5 PAFAH1B1

1.13e-05368222328561
Pubmed

Murine models of VACTERL syndrome: Role of sonic hedgehog signaling pathway.

GLI2 GLI3

1.13e-05368211172440
Pubmed

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.

VPS13C VPS13A

1.13e-05368230093493
Pubmed

Fuzzy modeling reveals a dynamic self-sustaining network of the GLI transcription factors controlling important metabolic regulators in adult mouse hepatocytes.

GLI2 GLI3

1.13e-05368226010061
Pubmed

Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23-H1.

NME2P1 NME2

1.13e-0536828270257
Pubmed

T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.

RAG1 RICTOR

1.13e-05368224315998
Pubmed

The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chains.

IL10RB IL20RA

1.13e-05368215178681
Pubmed

Myotubularin-deficient myoblasts display increased apoptosis, delayed proliferation, and poor cell engraftment.

RAG1 MTM1

1.13e-05368222841819
Pubmed

Gli family members are differentially expressed during the mitotic phase of spermatogenesis.

GLI2 GLI3

1.13e-0536829178901
Pubmed

Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers.

GLI2 GLI3

1.13e-0536828378770
Pubmed

IL-17C/IL-17 Receptor E Signaling in CD4+ T Cells Promotes TH17 Cell-Driven Glomerular Inflammation.

RAG1 IL17RE

1.13e-05368229483158
Pubmed

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene.

GLI2 GLI3

1.13e-0536828387379
Pubmed

Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase.

GLI2 GLI3

1.13e-05368238968120
Pubmed

Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.

GLI2 GLI3

1.13e-05368216571352
Pubmed

Chronic Lymphocytic Leukemia-Derived IL-10 Suppresses Antitumor Immunity.

IL10RB RAG1

1.13e-05368229712773
Pubmed

Different expression patterns of Gli1-3 in mouse embryonic maxillofacial development.

GLI2 GLI3

1.13e-05368222178118
Pubmed

Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase.

GLI2 GLI3

1.13e-05368219955409
Pubmed

TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes.

VPS13C VPS13A

1.13e-05368233087848
Pubmed

Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth.

GLI2 GLI3

1.13e-05368225695606
Pubmed

Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.

GLI2 GLI3 HDAC1

1.23e-052368321937600
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

CAD ZMYM2 CBX3 HDAC1 TBL1X

1.29e-0515368526365490
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ZBED4 ZNF592 VPS13C VPS13A PKHD1 CSMD2 MEGF10 HDAC1 ZNF304

1.31e-0573668929676528
Pubmed

Post-translational modification of OCT4 in breast cancer tumorigenesis.

CAD IGF2R PAFAH1B1

1.40e-052468329511337
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

CAD RACK1 ZBED4 ZNF592 BAZ2A ZMYM2 CBX3 HDAC1

1.82e-0558368829844126
Pubmed

The functional interactome landscape of the human histone deacetylase family.

CAD ZNF592 ZMYM2 CDYL HDAC1 TBL1X

2.22e-0528968623752268
Pubmed

Cloning and sequencing of the mouse Gli2 gene: localization to the Dominant hemimelia critical region.

GLI2 GLI3

2.25e-0546829027508
Pubmed

Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina.

GLI2 GLI3

2.25e-05468222281533
Pubmed

Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.

GLI2 GLI3

2.25e-05468227793025
Pubmed

Non-canonical activation of hedgehog in prostate cancer cells mediated by the interaction of transcriptionally active androgen receptor proteins with Gli3.

GLI2 GLI3

2.25e-05468229429990
Pubmed

Expression profile of Gli family members and Shh in normal and mutant mouse limb development.

GLI2 GLI3

2.25e-0546829438426
Pubmed

Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R.

IL10RB IL20RA

2.25e-05468210875937
Pubmed

Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development.

GLI2 GLI3

2.25e-0546828150204
Pubmed

The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment.

GLI2 GLI3

2.25e-05468224952464
Pubmed

The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription.

BAZ2A HDAC1

2.25e-05468212198165
Pubmed

The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses.

RAG1 RICTOR

2.25e-05468234031386
Pubmed

Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1.

GLI2 GLI3

2.25e-05468210531011
Pubmed

Cdyl: a new transcriptional co-repressor.

CDYL HDAC1

2.25e-05468212947414
Pubmed

The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway.

GLI2 HDAC1

2.25e-05468231558698
Pubmed

Analysis of the human VPS13 gene family.

VPS13C VPS13A

2.25e-05468215498460
Pubmed

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.

GLI2 GLI3

2.25e-0546829006072
Pubmed

IL-10 Regulates Memory T Cell Development and the Balance between Th1 and Follicular Th Cell Responses during an Acute Viral Infection.

IL10RB RAG1

2.25e-05468227402701
Pubmed

Maintenance of CD4 T cell fitness through regulation of Foxo1.

RAG1 RICTOR

2.25e-05468229988091
Pubmed

Anorectal malformations caused by defects in sonic hedgehog signaling.

GLI2 GLI3

2.25e-05468211485934
Pubmed

A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes.

GLI2 GLI3

2.25e-05468220956384
Pubmed

SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166.

PIK3AP1 PAFAH1B1 ITGA2

2.26e-052868332801337
Pubmed

Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma.

PRICKLE1 GLI2 GLI3

3.09e-053168322228100
Pubmed

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.

CAD CHD5 CUBN HDAC1

3.14e-059168420362542
Pubmed

ATRX proximal protein associations boast roles beyond histone deposition.

ZNF592 ZMYM2 CBX3 HDAC1

3.14e-059168434780483
Pubmed

Functional compensation in Hedgehog signaling during mouse prostate development.

GLI2 GLI3

3.75e-05568216707121
Pubmed

Genomic organization, chromosomal assignment, and expression analysis of the mouse suppressor of fused gene (Sufu) coding a Gli protein partner.

GLI3 FBXW4

3.75e-05568210920228
Pubmed

Evidence for the involvement of the Gli gene family in embryonic mouse lung development.

GLI2 GLI3

3.75e-0556829268579
Pubmed

Sonic hedgehog signals to multiple prostate stromal stem cells that replenish distinct stromal subtypes during regeneration.

GLI2 GLI3

3.75e-05568224218555
Pubmed

Expression of the mouse Fgf15 gene is directly initiated by Sonic hedgehog signaling in the diencephalon and midbrain.

GLI2 GLI3

3.75e-05568215614767
Pubmed

Identification of a suppressive mechanism for Hedgehog signaling through a novel interaction of Gli with 14-3-3.

GLI2 GLI3

3.75e-05568219996099
Pubmed

A bacterial protein targets the BAHD1 chromatin complex to stimulate type III interferon response.

CBX3 HDAC1

3.75e-05568221252314
Pubmed

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation.

GLI2 GLI3

3.75e-05568216611981
Pubmed

Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling.

GLI2 GLI3

3.75e-05568226120032
Pubmed

SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factors.

GLI2 GLI3

3.75e-05568220711444
Pubmed

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro.

GLI2 GLI3

3.75e-0556829118802
Pubmed

Gli regulation by the opposing activities of fused and suppressor of fused.

GLI2 GLI3

3.75e-05568210806483
Pubmed

p53 modulates the activity of the GLI1 oncogene through interactions with the shared coactivator TAF9.

GLI2 GLI3

3.75e-05568226282181
Pubmed

Gli1 is a target of Sonic hedgehog that induces ventral neural tube development.

GLI2 GLI3

3.75e-0556829216996
Pubmed

PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms.

GLI2 GLI3

3.75e-05568217328886
Pubmed

Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning.

GLI2 GLI3

3.75e-05568215315762
Pubmed

STAT1 signaling shields T cells from NK cell-mediated cytotoxicity.

IL10RB RAG1

3.75e-05568230796216
Pubmed

Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli.

GLI2 GLI3

3.75e-05568210564661
Pubmed

Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment.

HDAC1 TBL1X

3.75e-05568218326024
Pubmed

Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma.

GLI2 GLI3

3.75e-05568219593328
Pubmed

Expression pattern of Irx1 and Irx2 during mouse digit development.

GLI2 GLI3

3.75e-05568211472848
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

PIK3AP1 VPS13C GLI3 CSMD1 MEGF10

4.54e-0519968523382691
Pubmed

Nerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells.

GLI2 GLI3

5.62e-05668221549329
Pubmed

Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest.

ZNF592 CSMD2

5.62e-05668220360844
Pubmed

RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.

GLI2 GLI3

5.62e-05668233895473
Pubmed

Targeted disruption of Sonic Hedgehog in the mouse adrenal leads to adrenocortical hypoplasia.

GLI2 GLI3

5.62e-05668219536807
Pubmed

Molecular embryology of the lung: then, now, and in the future.

GLI2 GLI3

5.62e-05668210330024
Pubmed

Expression of sonic hedgehog signaling molecules in normal, hyperplastic and carcinomatous endometrium.

GLI2 GLI3

5.62e-05668219432668
CytobandEnsembl 112 genes in cytogenetic band chrXq12

VSIG4 FRMD8P1

6.87e-0426682chrXq12
Cytoband10q24

FBXW4 LGI1

1.25e-033568210q24
Cytoband7p13

GLI3 ZMIZ2

1.55e-03396827p13
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SUSD4 CD46 CSMD1 CSMD2 CSMD3

4.95e-07575051179
GeneFamilyKelch like|BTB domain containing

KLHL7 GAN KEAP1

2.12e-0442503617
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL10RB IL17RE IL20RA

2.12e-0442503602
GeneFamilyPHD finger proteins|NuRD complex

CHD5 HDAC1

4.86e-04125021305
GeneFamilyWD repeat domain containing

RACK1 PAFAH1B1 FBXW4 ELP2 TBL1X

7.65e-04262505362
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL7 GAN KEAP1

6.05e-03134503861
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

ZBED4 MTM1 PAFAH1B1 VPS13A CDYL FRYL KEAP1

1.28e-05300687M8702
CoexpressionGSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP

PIK3AP1 NAMPT PAFAH1B1 KEAP1 SMOX HDAC1

1.35e-05200686M4387
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DOA PKHD1 CSMD1 CSMD3 FREM1 CACNA2D3

2.60e-07175676887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

VPS13C VSIG4 PKHD1 CSMD1 CSMD3 TBL1X

3.73e-0718667623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellwk_15-18-Epithelial-PNS-COL20A1+_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ITGA2 CSMD1 CSMD2 MEGF10 LGI1

7.06e-06177675b8cc6a7abf83a9844a5293b6cc4b19135b51fd53
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 RASAL3 PRICKLE1 ENPP1 PKHD1

7.87e-0618167541969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 RASAL3 PRICKLE1 ENPP1 PKHD1

7.87e-061816753f50e61dc2a52d71a5801584617607e6246adcf2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SUSD4 PKHD1 ITGA2 FREM1 CACNA2D3

9.70e-06189675975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SUSD4 PKHD1 ITGA2 FREM1 CACNA2D3

9.70e-061896757eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRICKLE1 GLI2 GLI3 FREM1 LRRC17

1.05e-05192675e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAMPT ENPP1 CSMD1 MEGF10 CACNA2D3

1.13e-05195675c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAMPT ENPP1 CSMD1 MEGF10 CACNA2D3

1.13e-05195675ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SUSD4 ITGA2 CSMD1 SMOX CSMD3

1.21e-05198675a54ae5275a510b49d7629f0908817a0c5f05020e
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SUSD4 ITGA2 CSMD1 SMOX CSMD3

1.21e-0519867534997e3896d0893fbe51bfb0d4660ccaca1c975e
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Basal_2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SUSD4 ITGA2 CSMD1 SMOX CSMD3

1.21e-05198675686eda427b075e788de38149eae82faf19bd5704
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

IL17RE VPS13C PKHD1 ITGA2 CACNA2D3

1.27e-052006752dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellNS-moderate-d_0-4-Epithelial-Basal|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRICKLE1 SMOX CACNA2D3

2.37e-0537673e41e6d3bad3135f3f9109312a2ad6f3206d21d6c
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RACK1 HLA-DOA VSIG4 CACNA2D3

5.43e-0513767486c32cd26fe3b23c1dcd8ace580231c5a6ec6d9e
ToppCellPND07-28-samps-Lymphocyte-B_cell-B_cell_2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MRM3 RASAL3 HLA-DOA CD46

5.43e-051376742544d1256f11da6e3bad24a871b2253e0ab20d01
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RACK1 HLA-DOA VSIG4 CACNA2D3

5.43e-051376748989103606b15dff300e44c1590cd867b3cf7833
ToppCellPND07-28-samps-Lymphocyte-B_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MRM3 RASAL3 HLA-DOA CD46

5.43e-05137674874e2eaa7846a2832f46b77c726d79f220a4a1cd
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GLI2 GLI3 PLCD4 MEGF10

8.34e-0515367495b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GLI2 GLI3 PLCD4 MEGF10

8.34e-05153674b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GLI2 GLI3 PLCD4 MEGF10

8.34e-051536743ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 TDRD6 FREM1 CACNA2D3

9.92e-05160674c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 TDRD6 FREM1 CACNA2D3

9.92e-0516067425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDIAS SUSD4 CHD5 CD46

1.07e-04163674953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN CSMD1 CSMD2 CSMD3

1.17e-041676743edb0570e583bb527165bcd8a4c25a042054043b
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGB ENPP1 RICTOR CUBN

1.28e-041716746f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGB ENPP1 RICTOR CUBN

1.28e-04171674ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCellE16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASAL3 PRICKLE1 VPS13A SMOX

1.46e-0417767484591e28482ab62a5ef41e61043eb64912766356
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 NAMPT RNF216 CUBN

1.46e-04177674c2b8a3a149d70f77612759dea34df9e43953c566
ToppCellE16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASAL3 PRICKLE1 VPS13A SMOX

1.46e-041776744bc100062891d07cacd10ffba38966cc6302c92f
ToppCellE16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASAL3 PRICKLE1 VPS13A SMOX

1.46e-041776749f3a2adb9cd4f0a059afc87b6e377a9702154bb1
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 NAMPT RNF216 CUBN

1.46e-04177674384f841aa7b2d05815af7885e481f5affc55d897
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDIAS ENPP1 CACNA2D3 LGI1

1.46e-041776746b4fe717928814dafcd13090b1c90ea973938c6d
ToppCellfacs-Thymus-Epithelium-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 NAMPT RNF216 CUBN

1.46e-041776740e9e44119653abfd270e602e5e477a15e774638f
ToppCelldroplet-Bladder-nan-24m-Epithelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD5 CSMD1 MEGF10 LGI1

1.53e-041796743d6bb3cfe89d60f2f00aead9341f9967e5313763
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAN CSMD1 MEGF10 LGI1

1.56e-04180674da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAN CSMD1 MEGF10 LGI1

1.56e-041806745b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAN CSMD1 MEGF10 LGI1

1.56e-0418067450758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUSD4 CSMD1 MEGF10 LGI1

1.59e-04181674098dbb3e0ff531c9720a233123250c1e39a97d4c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 ENPP1 PKHD1 TBL1X

1.59e-041816746956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SUSD4 ITGA2 FREM1 CACNA2D3

1.63e-041826745f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 SUSD4 PKHD1 CACNA2D3

1.63e-04182674eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCelldroplet-Heart-nan-18m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RE CHD5 CSMD1 LGI1

1.66e-041836741701c8c212f1fdb6e4764375542a203e19753d14
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAMPT HLA-DOA VSIG4 CACNA2D3

1.66e-0418367492d5a61b57851090eba558f19e2a7010043eff81
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLCD4 ITGA2 FREM1 CACNA2D3

1.66e-041836742e831a4d99c6f983793df71c0994124c943c6da9
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

PIK3AP1 VPS13A PKHD1 CUBN

1.70e-0418467451ed1ebfdef45149541917c66cbacad87072e51f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 CSMD1 CSMD3 FREM1

1.70e-041846742cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 CSMD1 CSMD3 FREM1

1.70e-04184674ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 CSMD1 CSMD3 FREM1

1.70e-041846742b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

VPS13C MTM1 CD46 FRYL

1.73e-04185674a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLI2 MEGF10 FREM1 LGI1

1.73e-04185674785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLI2 MEGF10 FREM1 LGI1

1.73e-0418567497a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

VPS13C MTM1 CD46 FRYL

1.77e-041866748571956890fc9894d766ba294a28e376b4aba428
ToppCell3'_v3-blood-Myeloid_Dendritic-DC2|blood / Manually curated celltypes from each tissue

HLA-DOA NME2 SMOX CACNA2D3

1.81e-041876749f3db9f0e5de34aeabfe5984f675bc7a65435df7
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

IL17RE PKHD1 HID1 ITGA2

1.81e-04187674db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GLI2 GLI3 FREM1 LRRC17

1.81e-04187674a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SUSD4 PKHD1 ITGA2 CACNA2D3

1.81e-0418767477886f99c229610abd28c4c370d2c7d1536c9782
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

SUSD4 PKHD1 ITGA2 CACNA2D3

1.84e-04188674df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NAMPT IGF2R VSIG4 NME2

1.84e-041886745f6ad5d693145d846ca561c2fa55465a88e40b90
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SUSD4 IL17RE VPS13A PKHD1

1.84e-04188674beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAN CD46 CSMD1 LRRC17

1.88e-04189674544d95df910f1b276995624509a7e41b219baca0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SUSD4 ITGA2 FREM1 CACNA2D3

1.88e-04189674977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellControl|World / Disease state, Lineage and Cell class

PIK3AP1 NAMPT VSIG4 SMOX

1.88e-04189674fb8dddd3b901081c6bb9ed6f32dafc5cce5f30be
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GLI3 CSMD3 FREM1 LRRC17

1.88e-04189674203c80030df08ae112f9ae4043709f455d87ce89
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

IGF2R CBX3 FREM1 LRRC17

1.88e-041896740c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP1 GLI3 FREM1 LRRC17

1.92e-041906748cb950effc449ae59a915132ecc079be54d1acfe
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP1 GLI3 FREM1 LRRC17

1.92e-041906745dfbd064ab1f8a0b18b5975c47f8e79697f3db15
ToppCellfacs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP1 CSMD1 MEGF10 CACNA2D3

1.92e-04190674c7bd087f36321cec61b98657433b4d19d135791f
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP1 GLI3 FREM1 LRRC17

1.92e-0419067417a73a658fb30a4322b31e38db7b240023738f29
ToppCellfacs-Lung-nan-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP1 CSMD1 MEGF10 CACNA2D3

1.92e-04190674834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SUSD4 ITGA2 FREM1 CACNA2D3

1.92e-04190674e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ENPP1 CSMD1 MEGF10 CACNA2D3

1.96e-04191674fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-B_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PIK3AP1 RACK1 HLA-DOA NME2

1.96e-0419167431169e01072e5fea364178264a35754b6cf2c93b
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GLI2 GLI3 CSMD2 MEGF10

2.00e-0419267467e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCellfacs-Thymus-Flowthrough-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 IGF2R RASAL3 CBX3

2.00e-041926747a0ef1702d6538e5611cfdc633d8558f9523845c
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 IGF2R RASAL3 CBX3

2.00e-0419267405043fb75319b64f5ed7aee6a232309dcae891b8
ToppCellsevere-Myeloid-Neutrophils_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NAMPT IGF2R CD46 TBL1X

2.04e-04193674f4d43dfbf4115dd0f843ea5cf08049220342a047
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SUSD4 PKHD1 HID1 ITGA2

2.04e-041936745f0eba7b1440beb891d94a288f7f18a4e13c3a88
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRICKLE1 NME2 CSMD3 LRRC17

2.04e-0419367468089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-conventional_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DOA VSIG4 NME2 CACNA2D3

2.04e-04193674984ea5b871479527ab57dd813bacae844c0d8c06
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-conventional_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DOA VSIG4 NME2 CACNA2D3

2.04e-04193674529281b912070c8655e38880ac73f5e4bd6ee4ce
ToppCellsevere-Myeloid-Neutrophils_3|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NAMPT IGF2R CD46 TBL1X

2.08e-041946741f8edab1c8ba48bc0114429ea47aab378b5830b7
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GLI3 CSMD3 FREM1 LRRC17

2.08e-0419467499577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SUSD4 PKHD1 HID1 ITGA2

2.08e-04194674acd5ba9a097595d4caab4f05440531c65a4aa7bc
ToppCellP28-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ENPP1 CSMD1 MEGF10 CACNA2D3

2.08e-041946743c661c6768c3f05d2aba03d329adb257ca201b2d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GLI3 CSMD3 FREM1 LRRC17

2.12e-0419567470387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NAMPT CSMD1 CSMD2 LGI1

2.12e-04195674d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NAMPT CSMD1 CSMD2 LGI1

2.12e-0419567419853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell(3)_DC_2|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

NAMPT HLA-DOA VSIG4 CACNA2D3

2.12e-041956743d656e13f1440a3624fe890f59343f7313b51740
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VPS13A CSMD1 CSMD3 CACNA2D3

2.12e-041956742e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 GLI2 GLI3 FREM1

2.16e-04196674a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GLI2 GLI3 FREM1 LRRC17

2.16e-04196674dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

SUSD4 PKHD1 ITGA2 CACNA2D3

2.16e-0419667404f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellPCW_07-8.5-Mesenchymal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GLI2 GLI3 FREM1 LRRC17

2.16e-041966748e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 GLI2 GLI3 FREM1

2.16e-041966743e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3AP1 HLA-DOA VSIG4 CACNA2D3

2.16e-04196674fa24d7c4b7c65e98b209db302a16c58ceac1a105
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

VPS13C PKHD1 ITGA2 CSMD2

2.20e-04197674b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

GLI3 ITGA2 MEGF10 TBL1X

2.20e-0419767461749ccafeb938c310cff1de5ff924a1c794325a
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

PRICKLE1 GLI2 GLI3 CSMD2

2.20e-04197674f1c8936986123a3151140c374fcd62d6705c530b
DiseaseColorectal Carcinoma

CAD NAMPT GLI3 CHD5 VPS13A PKHD1 CD46 CUBN NME2 CSMD3 ZNF572

4.18e-077026611C0009402
DiseaseParkinson's disease 23 (implicated_via_orthology)

VPS13C VPS13A

4.93e-062662DOID:0060896 (implicated_via_orthology)
Diseasechoreaacanthocytosis (implicated_via_orthology)

VPS13C VPS13A

4.93e-062662DOID:0050766 (implicated_via_orthology)
Diseaseautosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)

VPS13C VPS13A

1.48e-053662DOID:0111611 (implicated_via_orthology)
DiseaseCohen syndrome (implicated_via_orthology)

VPS13C VPS13A

1.48e-053662DOID:0111590 (implicated_via_orthology)
Diseasebombesin receptor-activated protein C6orf89 measurement

RASAL3 CUBN

4.91e-055662EFO_0801428
Diseasecerebellar ataxia (implicated_via_orthology)

VPS13C VPS13A

1.37e-048662DOID:0050753 (implicated_via_orthology)
Diseaseresponse to vaccine

HLA-DOA CD46 CSMD1 CACNA2D3

1.64e-04122664EFO_0004645
Diseaseprimary bacterial infectious disease (implicated_via_orthology)

GLI2 GLI3

1.76e-049662DOID:0050338 (implicated_via_orthology)
Diseasehealth literacy measurement

GLI3 GAN CSMD1

2.31e-0453663EFO_0010104
Diseasesquamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma

PKHD1 CSMD1

3.78e-0413662EFO_0000707, EFO_0004193, EFO_0007932
Diseasegallbladder cancer (is_implicated_in)

RICTOR KEAP1

3.78e-0413662DOID:3121 (is_implicated_in)
Diseasebreast carcinoma (is_marker_for)

IGF2R CD46 HDAC1

4.42e-0466663DOID:3459 (is_marker_for)
DiseaseCongenital hernia of foramen of Morgagni

IGF2R FREM1

8.22e-0419662C0265699
DiseaseCongenital hernia of foramen of Bochdalek

IGF2R FREM1

8.22e-0419662C0265700
DiseaseCongenital diaphragmatic hernia

IGF2R FREM1

1.01e-0321662C0235833
Diseaseserum IgG glycosylation measurement

PIK3AP1 HLA-DOA VPS13C GLI3 CSMD1 MEGF10

1.11e-03523666EFO_0005193
Diseasemultiple sclerosis

IL10RB IGF2R PRICKLE1 IL20RA KEAP1 CSMD1

2.12e-03594666MONDO_0005301

Protein segments in the cluster

PeptideGeneStartEntry
YEDNAHCVWVITTTD

CSMD1

431

Q96PZ7
PYEHNLNCIWTIEAE

CSMD2

1291

Q7Z408
YHNNADCTWTIVAEP

CSMD3

261

Q7Z407
AFYEERLTWHSCPED

CBX3

166

Q13185
TADTVIIYDSDWNPH

CHD5

1111

Q8TDI0
AYCEHLSDSQEDITW

BAZ2A

1551

Q9UIF9
IEEWASYSCPEEVLS

CFAP46

1421

Q8IYW2
WQELTCDDEPETYVA

PIK3AP1

121

Q6ZUJ8
EVWRSNPYHESVEEL

RAG1

761

P15918
SCEEVFETIIHSYDW

RASAL3

561

Q86YV0
GVCKYTVQDESHSEW

RACK1

136

P63244
EHVVECISWAPESSY

PAFAH1B1

276

P43034
PEELVDYKSCAHDWV

NME2

136

P22392
PNVCSHWESYSVTVQ

MEGF10

31

Q96KG7
KQEPEVIYETNCHWE

GLI3

471

P10071
DRNHTWLPVSDDACY

CD46

81

P15529
CWTYETAVALDTEIP

HDAC1

311

Q13547
YDNPWHCTCEIETLI

LRRC17

161

Q8N6Y2
CFQELSWDHTSPEEE

FRMD8P1

316

Q9BZ68
HQWALECEELSSPYD

IL17RE

206

Q8NFR9
YPFAECHETDSDEWV

DDIAS

851

Q8IXT1
QPVAYDDEEEAWRCH

FRYL

2676

O94915
SHIEWSQTEYEVCEN

FREM1

1741

Q5H8C1
EVVIYETNCHWEDCT

GLI2

431

P10070
YQETCIEPEHIWTCN

ENPP1

136

P22413
ECYDTRTESWHTKPS

KLHL7

401

Q8IXQ5
VVVCDESNSIYPWDA

ITGA2

176

P17301
FQDIPYSDWCEQTIH

RICTOR

1546

Q6R327
YSDWCEQTIHNPLEV

RICTOR

1551

Q6R327
TWLEPNTLYCVHVES

IL20RA

206

Q9UHF4
PTDLYTHQVACVENW

NPY6R

186

Q99463
HDETQWYEDSLECLS

PRICKLE1

511

Q96MT3
FSDFDIEPHTTCAWD

CUBN

2731

O60494
PSAEDVYDCQVEHWG

HLA-DOA

181

P06340
DTWEPEQHLVNCEEY

CDYL

91

Q9Y232
DEWSYCNTDLHPEHR

CACNA2D3

651

Q8IZS8
ESVECYDPRTQQWTA

GAN

436

Q9H2C0
EHSDWVNITFCPVDD

IL10RB

96

Q08334
EWEEPHDSTLYCLQT

FBXW4

331

P57775
VECYDPDTDTWSEVT

KEAP1

581

Q14145
PEINDWTHCVETSQS

ELP2

761

Q6IA86
PEFVTATECVHYFEW

IGF2R

141

P11717
SFVPDEYWQSLEVSH

PIGB

81

Q92521
SEELVYITHIDDPWT

TDRD6

986

O60522
DYPVILSLETHCSWE

PLCD4

376

Q9BRC7
HVEVQSYDSDWTEAP

MRM3

336

Q9HC36
PEELVDYKSCAHDWV

NME2P1

121

O60361
AEDVHSLDSCEYIWE

HID1

171

Q8IV36
LFTVENTDPECYWLT

NAMPT

131

P43490
AIEEDCWLDHPYFQS

RNF216

166

Q9NWF9
EESSQCLFVPDHWAE

PKHD1

1841

P08F94
VQDEIWCHDSYESDG

ZNF572

76

Q7Z3I7
HESEVFICAWNPVSD

TBL1X

231

O60907
TTDQYWVPCLHDETE

VPS13A

186

Q96RL7
DIVYPNVEESHWLSS

MTM1

326

Q13496
QECQEWVPDRESYVS

ZNF592

986

Q92610
YCIKSEQTWPSTHET

SUSD4

301

Q5VX71
FVWEDEAESHTLTYP

SMOX

386

Q9NWM0
DELSYICTHGEDWDV

VPS13C

2646

Q709C8
DDRSHYTCEVTWQTP

VSIG4

106

Q9Y279
TVVPWDHALDSQEYE

CAD

201

P27708
NSDYEEITIDPTCSW

ZMIZ2

666

Q8NF64
SCQTDDTWRTEYVPV

ZMYM2

871

Q9UBW7
EQIYPWDTCAAVHDV

UBR3

1281

Q6ZT12
WCEAEHEAPSEQSVS

ZNF304

56

Q9HCX3
WAIYVEDDCVVHLAP

PLAAT5

146

Q96KN8
WILEEESPSQSHLDC

ZNF487

96

B1APH4
EEVLEHSCDPLTYWN

ZBED4

1091

O75132
EWLGHTNATVEDIYC

LGI1

186

O95970