Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	SNARE binding	STXBP5L SEC24A SEC24B ABCC9 UNC13C	1.24e-04	136	71	5	GO:0000149
GeneOntologyMolecularFunction	growth factor binding	BMPR2 NKD2 PTPRZ1 IL6ST NRP1	2.35e-04	156	71	5	GO:0019838
GeneOntologyBiologicalProcess	axon extension involved in axon guidance	BMPR2 DSCAM SLIT3 NRP1	9.52e-07	22	72	4	GO:0048846
GeneOntologyBiologicalProcess	neuron projection extension involved in neuron projection guidance	BMPR2 DSCAM SLIT3 NRP1	9.52e-07	22	72	4	GO:1902284
GeneOntologyBiologicalProcess	positive regulation of axon extension involved in axon guidance	BMPR2 DSCAM NRP1	1.41e-06	7	72	3	GO:0048842
GeneOntologyBiologicalProcess	regulation of axon extension involved in axon guidance	BMPR2 DSCAM NRP1	2.68e-05	17	72	3	GO:0048841
GeneOntologyBiologicalProcess	neuron projection development	CARM1 TMEM106B BMPR2 TAOK3 DSCAM PTPRZ1 NFE2L2 SS18L1 SLIT3 SEC24B VPS13A FLRT2 ADGRV1 CDH1 NRP1	3.04e-05	1285	72	15	GO:0031175
GeneOntologyBiologicalProcess	regulation of locomotion	BMPR2 KRT16 DSCAM MTUS1 PTPRZ1 NFE2L2 NAV3 EMILIN2 LAMA4 FLRT2 CDH1 ITGAX IL6ST TMEFF2 NRP1	4.41e-05	1327	72	15	GO:0040012
GeneOntologyBiologicalProcess	regulation of cell migration	BMPR2 KRT16 MTUS1 PTPRZ1 NFE2L2 NAV3 EMILIN2 LAMA4 FLRT2 CDH1 ITGAX IL6ST TMEFF2 NRP1	6.50e-05	1211	72	14	GO:0030334
GeneOntologyBiologicalProcess	neuron projection morphogenesis	TMEM106B BMPR2 TAOK3 DSCAM PTPRZ1 SS18L1 SLIT3 VPS13A FLRT2 CDH1 NRP1	9.94e-05	802	72	11	GO:0048812
GeneOntologyBiologicalProcess	axon extension	BMPR2 DSCAM SLIT3 CDH1 NRP1	1.10e-04	135	72	5	GO:0048675
GeneOntologyBiologicalProcess	regulation of cell motility	BMPR2 KRT16 MTUS1 PTPRZ1 NFE2L2 NAV3 EMILIN2 LAMA4 FLRT2 CDH1 ITGAX IL6ST TMEFF2 NRP1	1.18e-04	1280	72	14	GO:2000145
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	TMEM106B BMPR2 TAOK3 DSCAM PTPRZ1 SS18L1 SLIT3 VPS13A FLRT2 CDH1 NRP1	1.20e-04	819	72	11	GO:0120039
GeneOntologyBiologicalProcess	heart morphogenesis	BMPR2 SLIT3 SEC24B ABCC9 FLRT2 TMEM100 NRP1	1.28e-04	321	72	7	GO:0003007
GeneOntologyBiologicalProcess	cell projection morphogenesis	TMEM106B BMPR2 TAOK3 DSCAM PTPRZ1 SS18L1 SLIT3 VPS13A FLRT2 CDH1 NRP1	1.29e-04	826	72	11	GO:0048858
GeneOntologyBiologicalProcess	neuron development	CARM1 TMEM106B BMPR2 TAOK3 DSCAM PTPRZ1 NFE2L2 SS18L1 SLIT3 SEC24B VPS13A FLRT2 ADGRV1 CDH1 NRP1	1.33e-04	1463	72	15	GO:0048666
GeneOntologyBiologicalProcess	cell migration involved in vasculogenesis	SETD2 NRP1	1.79e-04	6	72	2	GO:0035441
GeneOntologyBiologicalProcess	coronary vasculature development	SETD2 SEC24B ABCC9 NRP1	2.04e-04	83	72	4	GO:0060976
GeneOntologyBiologicalProcess	coronary vasculature morphogenesis	SETD2 SEC24B NRP1	2.26e-04	34	72	3	GO:0060977
GeneOntologyBiologicalProcess	positive regulation of response to external stimulus	RFTN1 ZDHHC18 BMPR2 SLAMF6 DSCAM PVR GPS2 EMILIN2 IL6ST NRP1	2.34e-04	738	72	10	GO:0032103
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	TMEM106B BMPR2 DSCAM PTPRZ1 SS18L1 SLIT3 SEC24B FLRT2 CDH1 NRP1	2.60e-04	748	72	10	GO:0048667
GeneOntologyBiologicalProcess	regulation of neuron projection development	CARM1 TMEM106B BMPR2 DSCAM PTPRZ1 NFE2L2 SS18L1 CDH1 NRP1	2.70e-04	612	72	9	GO:0010975
GeneOntologyBiologicalProcess	regulation of nervous system development	BMPR2 DSCAM PTPRZ1 SS18L1 FLRT2 CDH1 ITGAX IL6ST NRP1	3.16e-04	625	72	9	GO:0051960
GeneOntologyBiologicalProcess	positive regulation of cell projection organization	ATMIN TMEM106B BMPR2 DSCAM PTPRZ1 NFE2L2 SS18L1 NRP1	3.19e-04	494	72	8	GO:0031346
GeneOntologyBiologicalProcess	blood vessel development	SETD2 BMPR2 NFE2L2 CD34 SEC24B EMILIN2 LAMA4 ABCC9 ITGAX TMEM100 NRP1	3.56e-04	929	72	11	GO:0001568
GeneOntologyBiologicalProcess	establishment of skin barrier	FLG KRT16 CDH1	3.95e-04	41	72	3	GO:0061436
GeneOntologyBiologicalProcess	animal organ morphogenesis	CARM1 SETD2 BMPR2 DSCAM CD34 SLIT3 SEC24B ABCC9 FLRT2 CDH1 ITGAX TMEM100 NRP1	4.02e-04	1269	72	13	GO:0009887
GeneOntologyBiologicalProcess	regulation of axon extension	BMPR2 DSCAM CDH1 NRP1	4.82e-04	104	72	4	GO:0030516
GeneOntologyBiologicalProcess	vasculature development	SETD2 BMPR2 NFE2L2 CD34 SEC24B EMILIN2 LAMA4 ABCC9 ITGAX TMEM100 NRP1	5.07e-04	969	72	11	GO:0001944
GeneOntologyBiologicalProcess	coronary artery morphogenesis	SEC24B NRP1	5.31e-04	10	72	2	GO:0060982
GeneOntologyBiologicalProcess	regulation of response to external stimulus	RFTN1 ZDHHC18 BMPR2 SLAMF6 DSCAM MTUS1 NFE2L2 PVR GPS2 EMILIN2 MUC16 IL6ST NRP1	5.68e-04	1316	72	13	GO:0032101
GeneOntologyBiologicalProcess	positive regulation of nervous system development	BMPR2 DSCAM PTPRZ1 SS18L1 FLRT2 IL6ST NRP1	6.33e-04	418	72	7	GO:0051962
GeneOntologyBiologicalProcess	dendrite morphogenesis	TMEM106B DSCAM PTPRZ1 SS18L1 NRP1	6.44e-04	198	72	5	GO:0048813
GeneOntologyBiologicalProcess	positive regulation of ubiquitin-dependent protein catabolic process	TRAF7 NKD2 NFE2L2 RNF180	6.82e-04	114	72	4	GO:2000060
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection organization	CARM1 ATMIN TMEM106B BMPR2 DSCAM PTPRZ1 NFE2L2 SS18L1 CDH1 NRP1	6.84e-04	846	72	10	GO:0120035
GeneOntologyBiologicalProcess	negative regulation of dendrite development	CARM1 PTPRZ1	7.75e-04	12	72	2	GO:2000171
GeneOntologyBiologicalProcess	vasculogenesis	SETD2 CD34 TMEM100 NRP1	7.76e-04	118	72	4	GO:0001570
GeneOntologyBiologicalProcess	neuron projection extension	BMPR2 DSCAM SLIT3 CDH1 NRP1	7.87e-04	207	72	5	GO:1990138
GeneOntologyBiologicalProcess	regulation of cell projection organization	CARM1 ATMIN TMEM106B BMPR2 DSCAM PTPRZ1 NFE2L2 SS18L1 CDH1 NRP1	7.97e-04	863	72	10	GO:0031344
GeneOntologyBiologicalProcess	cell morphogenesis	TMEM106B BMPR2 TAOK3 DSCAM PTPRZ1 SS18L1 SLIT3 SEC24B VPS13A FLRT2 CDH1 NRP1	8.17e-04	1194	72	12	GO:0000902
GeneOntologyBiologicalProcess	regulation of extent of cell growth	BMPR2 DSCAM CDH1 NRP1	8.79e-04	122	72	4	GO:0061387
Domain	bZIP_Maf	NFE2L2 BACH2 BACH1	1.53e-05	13	72	3	IPR004826
Domain	bZIP_Maf	NFE2L2 BACH2 BACH1	1.53e-05	13	72	3	PF03131
Domain	-	NFE2L2 BACH2 BACH1	2.97e-05	16	72	3	1.10.880.10
Domain	Sec23/24_helical_dom	SEC24A SEC24B	2.18e-04	6	72	2	IPR006900
Domain	Sec23_24_beta_S	SEC24A SEC24B	2.18e-04	6	72	2	IPR012990
Domain	zf-Sec23_Sec24	SEC24A SEC24B	2.18e-04	6	72	2	PF04810
Domain	Sec23_trunk	SEC24A SEC24B	2.18e-04	6	72	2	PF04811
Domain	Sec23_helical	SEC24A SEC24B	2.18e-04	6	72	2	PF04815
Domain	Sec23_BS	SEC24A SEC24B	2.18e-04	6	72	2	PF08033
Domain	Sec23/24_trunk_dom	SEC24A SEC24B	2.18e-04	6	72	2	IPR006896
Domain	Znf_Sec23_Sec24	SEC24A SEC24B	2.18e-04	6	72	2	IPR006895
Domain	bZIP_1	NFE2L2 BACH2 BACH1	3.02e-04	34	72	3	PF00170
Domain	TF_DNA-bd	NFE2L2 BACH2 BACH1	3.88e-04	37	72	3	IPR008917
Domain	fn3	DSCAM PTPRZ1 MYOM2 FLRT2 IL6ST	4.04e-04	162	72	5	PF00041
Domain	FN3	DSCAM PTPRZ1 MYOM2 FLRT2 IL6ST	7.39e-04	185	72	5	SM00060
Domain	FN3	DSCAM PTPRZ1 MYOM2 FLRT2 IL6ST	1.02e-03	199	72	5	PS50853
Domain	BRLZ	NFE2L2 BACH2 BACH1	1.06e-03	52	72	3	SM00338
Domain	BZIP	NFE2L2 BACH2 BACH1	1.12e-03	53	72	3	PS50217
Domain	BZIP_BASIC	NFE2L2 BACH2 BACH1	1.12e-03	53	72	3	PS00036
Domain	bZIP	NFE2L2 BACH2 BACH1	1.18e-03	54	72	3	IPR004827
Domain	FN3_dom	DSCAM PTPRZ1 MYOM2 FLRT2 IL6ST	1.27e-03	209	72	5	IPR003961
Domain	Gelsolin	SEC24A SEC24B	1.29e-03	14	72	2	PF00626
Domain	Gelsolin-like_dom	SEC24A SEC24B	1.29e-03	14	72	2	IPR007123
Domain	IGv	DSCAM PVR MPZL1	3.04e-03	75	72	3	SM00406
Domain	ADF-H/Gelsolin-like_dom	SEC24A SEC24B	3.83e-03	24	72	2	IPR029006
Domain	-	SEC24A SEC24B	3.83e-03	24	72	2	3.40.20.10
Domain	-	SLAMF6 DSCAM PTPRZ1 PVR MPZL1 MYOM2 FLRT2 IL6ST	3.91e-03	663	72	8	2.60.40.10
Domain	Ig-like_fold	SLAMF6 DSCAM PTPRZ1 PVR MPZL1 MYOM2 FLRT2 IL6ST	5.69e-03	706	72	8	IPR013783
Domain	-	SLIT3 LAMA4 ADGRV1	5.90e-03	95	72	3	2.60.120.200
Domain	VWF_A	SEC24A SEC24B ITGAX	6.61e-03	99	72	3	IPR002035
Domain	LRRCT	SLIT3 FLRT2	6.75e-03	32	72	2	PF01463
Domain	Ig_V-set	SLAMF6 DSCAM PVR MPZL1	7.32e-03	199	72	4	IPR013106
Domain	Znf-RING_LisH	TRAF7 RC3H2	7.59e-03	34	72	2	IPR027370
Domain	zf-RING_UBOX	TRAF7 RC3H2	7.59e-03	34	72	2	PF13445
Pubmed	Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site.	NFE2L2 BACH2 BACH1	1.77e-07	6	73	3	8887638
Pubmed	Comparative analysis of the expression of cytokeratins (1, 10, 14, 16, 4), involucrin, filaggrin and e-cadherin in plane warts and epidermodysplasia verruciformis plane wart-type lesions.	FLG KRT16 CDH1	4.93e-07	8	73	3	19515043
Pubmed	Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b.	SEC24A SEC24B CDH1	1.93e-06	12	73	3	20215345
Pubmed	Arkadia (RING Finger Protein 111) Mediates Sumoylation-Dependent Stabilization of Nrf2 Through K48-Linked Ubiquitination.	NFE2L2 RNF111	4.35e-06	2	73	2	29597191
Pubmed	Infection perturbs Bach2- and Bach1-dependent erythroid lineage 'choice' to cause anemia.	BACH2 BACH1	4.35e-06	2	73	2	30250186
Pubmed	Palmitate-induced endothelial dysfunction is attenuated by cyanidin-3-O-glucoside through modulation of Nrf2/Bach1 and NF-κB pathways.	NFE2L2 BACH1	4.35e-06	2	73	2	26422990
Pubmed	MicroRNA-based regulatory mechanisms underlying the synergistic antioxidant action of quercetin and catechin in H2O2-stimulated HepG2 cells: Roles of BACH1 in Nrf2-dependent pathways.	NFE2L2 BACH1	4.35e-06	2	73	2	32344103
Pubmed	Salvianolic acid B, an antioxidant derived from Salvia militarize, protects mice against γ‑radiation‑induced damage through Nrf2/Bach1.	NFE2L2 BACH1	4.35e-06	2	73	2	30535483
Pubmed	BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17.	CARM1 BACH1	4.35e-06	2	73	2	37995178
Pubmed	Lipoxin A4 attenuates LPS-induced mouse acute lung injury via Nrf2-mediated E-cadherin expression in airway epithelial cells.	NFE2L2 CDH1	4.35e-06	2	73	2	26845617
Pubmed	The double knockout of Bach1 and Bach2 in mice reveals shared compensatory mechanisms in regulating alveolar macrophage function and lung surfactant homeostasis.	BACH2 BACH1	4.35e-06	2	73	2	27387751
Pubmed	Aberration of Nrf2‑Bach1 pathway in colorectal carcinoma; role in carcinogenesis and tumor progression.	NFE2L2 BACH1	4.35e-06	2	73	2	30597358
Pubmed	Barrier proteins and eosinophilic esophagitis in children: the role of E-cadherin and filaggrin.	FLG CDH1	4.35e-06	2	73	2	35789411
Pubmed	Bach2 is involved in neuronal differentiation of N1E-115 neuroblastoma cells.	BACH2 BACH1	4.35e-06	2	73	2	16631738
Pubmed	Crystal structure of the Bach1 BTB domain and its regulation of homodimerization.	BACH2 BACH1	4.35e-06	2	73	2	19170764
Pubmed	Oxidative stress and dysfunctional NRF2 underlie pachyonychia congenita phenotypes.	KRT16 NFE2L2	4.35e-06	2	73	2	27183391
Pubmed	Activation of the Nrf2 pathway by inorganic arsenic in human hepatocytes and the role of transcriptional repressor Bach1.	NFE2L2 BACH1	4.35e-06	2	73	2	23738048
Pubmed	Novel insights into the regulation of antioxidant-response-element-mediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2.	NFE2L2 BACH1	4.35e-06	2	73	2	21812759
Pubmed	Pirfenidone attenuates bleomycin-induced pulmonary fibrosis in mice by regulating Nrf2/Bach1 equilibrium.	NFE2L2 BACH1	4.35e-06	2	73	2	28420366
Pubmed	Increased pachyonychia congenita severity in patients with concurrent keratin and filaggrin mutations.	FLG KRT16	4.35e-06	2	73	2	19785597
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAGI1 BMPR2 RESF1 NKD2 MTUS1 SEC24A SEC24B BACH1 USP54 RNF180	1.25e-05	861	73	10	36931259
Pubmed	A novel CXCR3-B chemokine receptor-induced growth-inhibitory signal in cancer cells is mediated through the regulation of Bach-1 protein and Nrf2 protein nuclear translocation.	NFE2L2 BACH1	1.30e-05	3	73	2	24366869
Pubmed	Role of Bach1 and Nrf2 in up-regulation of the heme oxygenase-1 gene by cobalt protoporphyrin.	NFE2L2 BACH1	1.30e-05	3	73	2	17065227
Pubmed	ERK1 loss accelerates the progression of osteoarthritis in aged mice via NRF2/BACH1 signaling.	NFE2L2 BACH1	1.30e-05	3	73	2	35849954
Pubmed	Genetic alterations in squamous cell lung cancer associated with idiopathic pulmonary fibrosis.	SETD2 NFE2L2	1.30e-05	3	73	2	33533494
Pubmed	Bach1 differentially regulates distinct Nrf2-dependent genes in human venous and coronary artery endothelial cells adapted to physiological oxygen levels.	NFE2L2 BACH1	1.30e-05	3	73	2	26698668
Pubmed	Gold nanoparticles induce heme oxygenase-1 expression through Nrf2 activation and Bach1 export in human vascular endothelial cells.	NFE2L2 BACH1	1.30e-05	3	73	2	26445536
Pubmed	Keratin and filaggrin expression in keratoacanthoma.	FLG KRT16	1.30e-05	3	73	2	18005116
Pubmed	Bach1 competes with Nrf2 leading to negative regulation of the antioxidant response element (ARE)-mediated NAD(P)H:quinone oxidoreductase 1 gene expression and induction in response to antioxidants.	NFE2L2 BACH1	1.30e-05	3	73	2	15734732
Pubmed	A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors.	BACH2 BACH1	1.30e-05	3	73	2	28273455
Pubmed	Cadmium induces nuclear export of Bach1, a transcriptional repressor of heme oxygenase-1 gene.	NFE2L2 BACH1	1.30e-05	3	73	2	14504288
Pubmed	Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17.	KRT16 NFE2L2	1.30e-05	3	73	2	28576737
Pubmed	Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology.	TMEM106B ABCC9	1.30e-05	3	73	2	25470345
Pubmed	Raftlin is recruited by neuropilin-1 to the activated VEGFR2 complex to control proangiogenic signaling.	RFTN1 NRP1	1.30e-05	3	73	2	32274611
Pubmed	MTBP Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Enhancing the MDM2-Mediated Degradation of E-Cadherin.	MTBP CDH1	1.30e-05	3	73	2	26280083
Pubmed	E-cadherin inhibits nuclear accumulation of Nrf2: implications for chemoresistance of cancer cells.	NFE2L2 CDH1	1.30e-05	3	73	2	22302998
Pubmed	Cigarette Smoke Regulates the Competitive Interactions between NRF2 and BACH1 for Heme Oxygenase-1 Induction.	NFE2L2 BACH1	1.30e-05	3	73	2	29125538
Pubmed	Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene.	NFE2L2 BACH1	1.30e-05	3	73	2	12356737
Pubmed	Immunohistochemical study of the Nrf2 pathway in colorectal cancer: Nrf2 expression is closely correlated to Keap1 in the tumor and Bach1 in the normal tissue.	NFE2L2 BACH1	1.30e-05	3	73	2	23455180
Pubmed	Repurposing the CRISPR-Cas9 system for targeted DNA methylation.	BACH2 IL6ST	1.30e-05	3	73	2	26969735
Pubmed	The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program.	BACH2 BACH1	1.30e-05	3	73	2	25344725
Pubmed	RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice.	NFE2L2 BACH1	1.30e-05	3	73	2	27836987
Pubmed	MAGI-1 interacts with beta-catenin and is associated with cell-cell adhesion structures.	MAGI1 CDH1	1.30e-05	3	73	2	10772923
Pubmed	Mesothelial cells interact with tumor cells for the formation of ovarian cancer multicellular spheroids in peritoneal effusions.	MUC16 CDH1	1.30e-05	3	73	2	27612856
Pubmed	Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments.	CD34 CDH1 ITGAX	1.33e-05	22	73	3	21464233
Pubmed	Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2.	BACH2 BACH1	2.60e-05	4	73	2	21444915
Pubmed	A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domain.	BACH2 BACH1	2.60e-05	4	73	2	10669750
Pubmed	Prognostic and predictive values of Nrf2, Keap1, p16 and E-cadherin expression in ovarian epithelial carcinoma.	NFE2L2 CDH1	2.60e-05	4	73	2	26191276
Pubmed	Dual regulation of skin sensitizer-induced HMOX1 expression by Bach1 and Nrf2: Comparison to regulation of the AKR1C2-ARE element in the KeratinoSens cell line.	NFE2L2 BACH1	2.60e-05	4	73	2	26244607
Pubmed	Myristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membrane.	NKD2 CDH1	2.60e-05	4	73	2	20177058
Pubmed	Transcriptional regulation of the human ferritin gene by coordinated regulation of Nrf2 and protein arginine methyltransferases PRMT1 and PRMT4.	CARM1 NFE2L2	2.60e-05	4	73	2	23699174
Pubmed	The role of the C-terminal domain of PCSK9 and SEC24 isoforms in PCSK9 secretion.	SEC24A SEC24B	2.60e-05	4	73	2	32058034
Pubmed	Mutagenesis of the epithelial polarity gene, discs large 1, perturbs nephrogenesis in the developing mouse kidney.	DLGAP1 CDH1	4.33e-05	5	73	2	16105026
Pubmed	Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.	NFE2L2 BACH1	4.33e-05	5	73	2	24630724
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	MAGI1 DSCAM MTUS1 UNC13C	6.25e-05	101	73	4	18519826
Pubmed	Prolonged cigarette smoke exposure decreases heme oxygenase-1 and alters Nrf2 and Bach1 expression in human macrophages: roles of the MAP kinases ERK(1/2) and JNK.	NFE2L2 BACH1	6.48e-05	6	73	2	19822148
Pubmed	A family of mammalian proteins homologous to yeast Sec24p.	SEC24A SEC24B	6.48e-05	6	73	2	10329445
Pubmed	CD155 on HIV-Infected Cells Is Not Modulated by HIV-1 Vpu and Nef but Synergizes with NKG2D Ligands to Trigger NK Cell Lysis of Autologous Primary HIV-Infected Cells.	SLAMF6 PVR	6.48e-05	6	73	2	27296670
Pubmed	Sec24 proteins and sorting at the endoplasmic reticulum.	SEC24A SEC24B	6.48e-05	6	73	2	10075675
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	GMPS RFTN1 KRT16 MTUS1 CTDSPL2 PTPRZ1 SEC24A SEC24B MPZL1 VPS13A	6.63e-05	1049	73	10	27880917
Pubmed	Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.	BMPR2 LAMA4 CDH1	8.29e-05	40	73	3	27068110
Pubmed	Networks of bZIP protein-protein interactions diversified over a billion years of evolution.	NFE2L2 BACH2 BACH1	8.29e-05	40	73	3	23661758
Pubmed	Transforming growth factor-β induces transcription factors MafK and Bach1 to suppress expression of the heme oxygenase-1 gene.	NFE2L2 BACH1	9.06e-05	7	73	2	23737527
Pubmed	Selective export of human GPI-anchored proteins from the endoplasmic reticulum.	SEC24A SEC24B	9.06e-05	7	73	2	20427317
Pubmed	Nonmuscle myosin II isoform and domain specificity during early mouse development.	CD34 CDH1	9.06e-05	7	73	2	20679233
Pubmed	Identification of a shootin1 isoform expressed in peripheral tissues.	CDH1 ITGAX	1.21e-04	8	73	2	27177867
Pubmed	Specific activation of K-RasG12D allele in the bladder urothelium results in lung alveolar and vascular defects.	CD34 CDH1	1.21e-04	8	73	2	24760005
Pubmed	Cytokeratin, vimentin and E-cadherin immunodetection in the embryonic palate in two strains of mice with different susceptibility to glucocorticoid-induced clefting.	KRT16 CDH1	1.21e-04	8	73	2	11321598
Pubmed	SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion.	SEC24A SEC24B	1.21e-04	8	73	2	23580231
Pubmed	Increased expression of heme oxygenase-1 suppresses airway branching morphogenesis in fetal mouse lungs exposed to inflammation.	BACH1 NRP1	1.21e-04	8	73	2	31578032
Pubmed	Necl2 regulates epidermal adhesion and wound repair.	CD34 CDH1	1.21e-04	8	73	2	19783739
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	RFTN1 BMPR2 TAOK3 MPZL1 FLRT2 IL6ST	1.44e-04	377	73	6	38117590
Pubmed	Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis.	ATMIN CDH1	1.55e-04	9	73	2	20975950
Pubmed	Cyclic expression of lhx2 regulates hair formation.	CD34 CDH1	1.55e-04	9	73	2	20386748
Pubmed	Schizophrenia and vitamin D related genes could have been subject to latitude-driven adaptation.	MAGI1 DLGAP1	1.55e-04	9	73	2	21070662
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	DSCAM FLRT2 NRP1	1.82e-04	52	73	3	26633812
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	BMPR2 PTPRZ1 SLIT3 FLRT2 NRP1	1.89e-04	251	73	5	29031500
Pubmed	The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope.	SEC24A SEC24B	1.93e-04	10	73	2	17499046
Pubmed	The forming limb skeleton serves as a signaling center for limb vasculature patterning via regulation of Vegf.	CD34 NRP1	1.93e-04	10	73	2	19261698
Pubmed	Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis.	SS18L1 TEX15	1.93e-04	10	73	2	18283110
Pubmed	The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain.	ATMIN ITGAX	1.93e-04	10	73	2	20889973
Pubmed	Structural basis of cargo membrane protein discrimination by the human COPII coat machinery.	SEC24A SEC24B	1.93e-04	10	73	2	18843296
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	TRAF7 TMEM106B CLPTM1L BMPR2 PVR MPZL1 LAMA4 EWSR1 IL6ST NRP1	2.00e-04	1201	73	10	35696571
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	FCGBP PTPRZ1 PVR IL6ST NRP1	2.11e-04	257	73	5	16335952
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	KRT16 DSCAM SEC24A SEC24B MPZL1 VPS13A MUC16 FLRT2	2.24e-04	777	73	8	35844135
Pubmed	Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity.	CD34 NRP1	2.36e-04	11	73	2	15875024
Pubmed	A forward genetic screen in mice identifies mutants with abnormal cortical patterning.	CARM1 SEC24B	2.36e-04	11	73	2	23968836
Pubmed	DSCAM regulates delamination of neurons in the developing midbrain.	MAGI1 DSCAM	2.36e-04	11	73	2	32917586
Pubmed	Cell Surface Downregulation of NK Cell Ligands by Patient-Derived HIV-1 Vpu and Nef Alleles.	SLAMF6 PVR	2.36e-04	11	73	2	26656785
Pubmed	Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer.	CDH1 IL6ST	2.36e-04	11	73	2	10205167
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	DSCAM SLIT3 UNC13C IL6ST TMEFF2	2.43e-04	265	73	5	19240061
Pubmed	Roundabout receptors are critical for foregut separation from the body wall.	SLIT3 CDH1	2.83e-04	12	73	2	23328398
Pubmed	The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development.	CD34 CDH1	2.83e-04	12	73	2	16287848
Pubmed	Genome-wide association study of age at menarche in African-American women.	UNC13C FLRT2	2.83e-04	12	73	2	23599027
Pubmed	miRNA-17 members that target Bmpr2 influence signaling mechanisms important for embryonic stem cell differentiation in vitro and gastrulation in embryos.	BMPR2 CDH1	2.83e-04	12	73	2	25209090
Pubmed	Slits and Robo-2 regulate the coalescence of subsets of olfactory sensory neuron axons within the ventral region of the olfactory bulb.	SLIT3 NRP1	2.83e-04	12	73	2	22981605
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	GMPS CARM1 PTPRZ1 SEC24A SEC24B	2.94e-04	276	73	5	28319085
Pubmed	A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.	KRT16 NFE2L2 CDH1	3.07e-04	62	73	3	26644517
Pubmed	Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.	NAV3 MYOM2 CDH1 TMEM100	3.33e-04	156	73	4	22008794
Pubmed	CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development.	SETD2 CDH1	3.34e-04	13	73	2	24036311
GeneFamily	Fibronectin type III domain containing	DSCAM PTPRZ1 MYOM2 FLRT2 IL6ST	7.10e-05	160	49	5	555
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	SLAMF6 CD34 PVR CDH1 ITGAX IL6ST NRP1	8.63e-05	394	49	7	471
GeneFamily	Basic leucine zipper proteins	NFE2L2 BACH2 BACH1	3.16e-04	49	49	3	506
GeneFamily	CD molecules\|Mucins	OVGP1 MUC16	1.46e-03	21	49	2	648
GeneFamily	Immunoglobulin like domain containing	SLAMF6 DSCAM PVR MYOM2	1.83e-03	193	49	4	594
GeneFamily	Ring finger proteins	TRAF7 RC3H2 RNF180 RNF111	6.49e-03	275	49	4	58
Coexpression	GSE37301_PRO_BCELL_VS_CD4_TCELL_DN	SLAMF6 MTUS1 VPS13A NAV3 EWSR1 NRP1	5.80e-06	165	71	6	M8907
Coexpression	HAY_BONE_MARROW_STROMAL	MAGI1 FRMD4A TUSC3 SLIT3 NAV3 LAMA4 FLRT2 RNF180 TMEM100 IL6ST NRP1	6.49e-06	767	71	11	M39209
Coexpression	TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN	FRMD4A MGAM FCGBP KANSL1 MTUS1	2.99e-05	132	71	5	M15410
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000	KANSL1 NKD2 CTDSPL2 PTPRZ1 BACH2 VPS13A NAV3 LAMA4 MYOM2 FLRT2 RNF180 IL6ST	8.40e-06	769	71	12	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#5_top-relative-expression-ranked_100	GMPS MGAM BACH1	4.56e-05	21	71	3	gudmap_developingGonad_e11.5_ovary + mesonephros_k5_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_500	KANSL1 NKD2 PTPRZ1 BACH2 LAMA4 MYOM2 FLRT2 RNF180	4.67e-05	390	71	8	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 SLIT3 EMILIN2 LAMA4 ABCC9 FLRT2 TMEM100 TMEFF2	6.89e-10	183	73	8	5cfcd589a480e67654d3d94e71916f122150db10
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 SLIT3 EMILIN2 LAMA4 ABCC9 FLRT2 TMEM100 TMEFF2	6.89e-10	183	73	8	c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 SLIT3 EMILIN2 LAMA4 ABCC9 FLRT2 TMEM100 TMEFF2	6.89e-10	183	73	8	81003ddc24164959dd41bb12fcac72638789b8f2
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 SLIT3 EMILIN2 LAMA4 FLRT2 TMEM100 TMEFF2 NRP1	7.51e-10	185	73	8	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 SLIT3 EMILIN2 LAMA4 FLRT2 TMEM100 TMEFF2 NRP1	7.51e-10	185	73	8	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 SLIT3 EMILIN2 LAMA4 FLRT2 TMEM100 TMEFF2 NRP1	7.51e-10	185	73	8	a94694e226856bc5b168464f52d76004145717a5
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRMD4A DLGAP1 NKD2 BACH2 SLIT3 LAMA4 UNC13C NRP1	1.09e-09	194	73	8	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD34 SLIT3 EMILIN2 MYOM2 ADGRV1 TMEM100 TMEFF2	2.47e-08	187	73	7	0d4b7da81036c2aa678654b9fe49c939d08fcd9b
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 SLIT3 EMILIN2 LAMA4 FLRT2 TMEM100 TMEFF2	2.66e-08	189	73	7	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 SLIT3 EMILIN2 LAMA4 FLRT2 TMEM100 TMEFF2	2.76e-08	190	73	7	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 SLIT3 EMILIN2 LAMA4 FLRT2 TMEM100 TMEFF2	2.76e-08	190	73	7	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	MAGI1 DSCAM MTUS1 USP54 ADGRV1 CDH1 TMEFF2	2.86e-08	191	73	7	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	DLGAP1 NKD2 BACH2 SLIT3 LAMA4 UNC13C NRP1	3.07e-08	193	73	7	acad568621ed677031797b8c2e34dafea798d681
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 SLIT3 NAV3 LAMA4 ABCC9 FLRT2 NRP1	3.30e-08	195	73	7	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NKD2 BACH2 SLIT3 NAV3 LAMA4 FLRT2 NRP1	3.92e-08	200	73	7	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NKD2 BACH2 SLIT3 NAV3 LAMA4 FLRT2 NRP1	3.92e-08	200	73	7	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 SLIT3 EMILIN2 FLRT2 TMEM100 TMEFF2	3.55e-07	169	73	6	bb43abad2c049b7f4d307737347290e01b3339a3
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 SLIT3 EMILIN2 FLRT2 TMEM100 TMEFF2	3.55e-07	169	73	6	5f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 SLIT3 EMILIN2 FLRT2 TMEM100 TMEFF2	3.55e-07	169	73	6	8bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 NKD2 SLIT3 ABCC9 FLRT2 NRP1	4.82e-07	178	73	6	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 DSCAM MTUS1 USP54 ADGRV1 TMEFF2	4.98e-07	179	73	6	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLIT3 ABCC9 TEX15 TMEM100 TMEFF2 NRP1	4.98e-07	179	73	6	f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	MAGI1 MTUS1 ABCC9 USP54 ADGRV1 CDH1	5.66e-07	183	73	6	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLIT3 ABCC9 TEX15 TMEM100 TMEFF2 NRP1	5.66e-07	183	73	6	65f2a5895d166189a095cf7ea9dda171f0419b08
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM STXBP5L NAV3 UNC13C MYOM2 ADGRV1	5.85e-07	184	73	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 SLIT3 NAV3 LAMA4 FLRT2 NRP1	5.85e-07	184	73	6	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM STXBP5L NAV3 UNC13C MYOM2 ADGRV1	5.85e-07	184	73	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM STXBP5L NAV3 UNC13C MYOM2 ADGRV1	5.85e-07	184	73	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 MTUS1 UNC13C USP54 ADGRV1 CDH1	5.85e-07	184	73	6	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	DLGAP1 NKD2 SLIT3 NAV3 LAMA4 NRP1	6.43e-07	187	73	6	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD34 SLIT3 EMILIN2 LAMA4 TMEM100 TMEFF2	6.63e-07	188	73	6	aa516273cdde53c8c0295f06830972388f890c97
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 BMPR2 CD34 TUSC3 NAV3 TMEM100	6.63e-07	188	73	6	117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	MAGI1 MTUS1 ABCC9 USP54 ADGRV1 CDH1	6.63e-07	188	73	6	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	COPD-Epithelial-Mesothelial\|Epithelial / Disease state, Lineage and Cell class	CD34 BACH2 SLIT3 NAV3 LAMA4 FLRT2	6.63e-07	188	73	6	159d63ecc3653a7449fc6acefd6ef0464845260e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NWD2 DSCAM STXBP5L SLIT3 VPS13A FLRT2	7.05e-07	190	73	6	49e09cdb843b3d889a06a811aa5affae68b25a75
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 DLGAP1 SLIT3 LAMA4 ABCC9 NRP1	7.27e-07	191	73	6	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRMD4A BMPR2 NKD2 BACH2 LAMA4 NRP1	7.27e-07	191	73	6	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	10x5'v1-week_12-13-Endothelial-stroma-tip_EC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MAGI1 MTUS1 LAMA4 ABCC9 FLRT2 NRP1	7.27e-07	191	73	6	cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 MTUS1 USP54 ADGRV1 CDH1 TMEFF2	7.27e-07	191	73	6	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 DLGAP1 SLIT3 LAMA4 ABCC9 NRP1	7.50e-07	192	73	6	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMPR2 MTUS1 CD34 TMEM100 IL6ST NRP1	7.50e-07	192	73	6	eafead22bba48ac5ee568faa8946c444445c1034
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 SLIT3 LAMA4 ABCC9 FLRT2 NRP1	7.50e-07	192	73	6	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD34 SLIT3 EMILIN2 LAMA4 TMEM100 TMEFF2	7.50e-07	192	73	6	30cefa0990ba1f379f350bfbf994a78db145075e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 SLIT3 NAV3 LAMA4 ABCC9 FLRT2	7.50e-07	192	73	6	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 SLIT3 NAV3 LAMA4 ABCC9 FLRT2	7.50e-07	192	73	6	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 DLGAP1 SLIT3 LAMA4 ABCC9 NRP1	7.50e-07	192	73	6	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 SLIT3 LAMA4 ABCC9 FLRT2 NRP1	7.50e-07	192	73	6	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD34 SLIT3 EMILIN2 LAMA4 TMEM100 TMEFF2	7.96e-07	194	73	6	7b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DLGAP1 NKD2 SLIT3 NAV3 LAMA4 UNC13C	7.96e-07	194	73	6	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 SLIT3 LAMA4 ABCC9 FLRT2 NRP1	7.96e-07	194	73	6	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 RFTN1 MTUS1 USP54 ADGRV1 CDH1	7.96e-07	194	73	6	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD34 SLIT3 EMILIN2 FLRT2 TMEM100 TMEFF2	8.45e-07	196	73	6	ed6047b48b6a96baa6a90c7af784e7c34b32824d
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MAGI1 MTUS1 ABCC9 FLRT2 IL6ST NRP1	8.71e-07	197	73	6	f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-tip_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MAGI1 MTUS1 CD34 TUSC3 LAMA4 NRP1	8.71e-07	197	73	6	b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR2 CD34 LAMA4 TMEM100 IL6ST NRP1	8.97e-07	198	73	6	d5990cab01de6e6f3757f5a50ef70ced711bb1fa
ToppCell	COVID-19-kidney-Fibroblast-2\|kidney / Disease (COVID-19 only), tissue and cell type	RFTN1 SLIT3 NAV3 LAMA4 ABCC9 FLRT2	8.97e-07	198	73	6	ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD34 NAV3 LAMA4 FLRT2 TMEFF2 NRP1	9.24e-07	199	73	6	bfc157be6e9f84739848eb19b718de5b17f3fa88
ToppCell	COVID-19-kidney-Fibroblast-1\|kidney / Disease (COVID-19 only), tissue and cell type	RFTN1 SLIT3 LAMA4 ABCC9 FLRT2 NRP1	9.24e-07	199	73	6	9503646ff1ad248181146ce767e9d12e882ec3bd
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MAGI1 MTUS1 CD34 ABCC9 FLRT2 NRP1	9.51e-07	200	73	6	77ac1aa73c16a4f595ff01c6b4e171e0b8fed1e6
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NKD2 SLIT3 NAV3 LAMA4 FLRT2 NRP1	9.51e-07	200	73	6	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Neuronal-Excitatory\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RFTN1 NWD2 DSCAM STXBP5L SLIT3 NAV3	9.51e-07	200	73	6	4409065bc7aa995354c71e0f9d6f3726cf393d6b
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NKD2 BACH2 SLIT3 NAV3 LAMA4 NRP1	9.51e-07	200	73	6	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CD34 BACH2 SLIT3 NAV3 LAMA4 FLRT2	9.51e-07	200	73	6	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CD34 NAV3 LAMA4 ABCC9 FLRT2 NRP1	9.51e-07	200	73	6	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ZDHHC18 KRT16 STXBP5L MUC16 TMEM100	5.48e-06	154	73	5	212c340a096a3a9669d1aebd61c045cf1402a868
ToppCell	facs-Marrow-KLS-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 DSCAM ABCC9 ADGRV1 ITGAX	5.48e-06	154	73	5	37765512dfae557b9f6eb30a29463b93682a4404
ToppCell	droplet-Fat-Scat-21m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP CD34 TUSC3 MYOM2 CDH1	7.67e-06	165	73	5	3f0c2486ea357d10dad0b703cf75cc29bdd5b5cf
ToppCell	Control\|World / group, cell type (main and fine annotations)	MAGI1 DLGAP1 USP54 ADGRV1 CDH1	8.37e-06	168	73	5	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 SLIT3 TMBIM4 FLRT2 NRP1	8.37e-06	168	73	5	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 NAV3 LAMA4 FLRT2 TEX15	8.37e-06	168	73	5	4b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 NAV3 LAMA4 FLRT2 TEX15	9.12e-06	171	73	5	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM RFTN1 EMILIN2 MUC16 ITGAX	9.38e-06	172	73	5	72fbfa890995e47048b47199c170cc7dcd7661f8
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM RFTN1 EMILIN2 MUC16 ITGAX	9.38e-06	172	73	5	2ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	FRMD4A RFTN1 DLGAP1 SLIT3 LAMA4	9.38e-06	172	73	5	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	MAGI1 CD34 LAMA4 FLRT2 TMEM100	9.92e-06	174	73	5	d551bc29afef071adf4c9bb80345352ec33441d8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLIT3 ABCC9 TEX15 TMEFF2 NRP1	1.02e-05	175	73	5	90e29945aa861082c94bb4f331161adc3a6ef899
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLIT3 NAV3 LAMA4 FLRT2 TEX15	1.02e-05	175	73	5	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLIT3 ABCC9 TEX15 TMEFF2 NRP1	1.05e-05	176	73	5	e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCell	metastatic_Lymph_Node-Endothelial_cells\|metastatic_Lymph_Node / Location, Cell class and cell subclass	MAGI1 CD34 LAMA4 FLRT2 TMEM100	1.08e-05	177	73	5	71bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT16 NAV3 FLRT2 TMEFF2 NRP1	1.08e-05	177	73	5	7af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 MTUS1 USP54 ADGRV1 CDH1	1.11e-05	178	73	5	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD34 NAV3 LAMA4 FLRT2 IL6ST	1.11e-05	178	73	5	ad3de3e03a401dac64431a541899445262246347
ToppCell	COVID-19-kidney-Epi_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	FRMD4A RFTN1 SLIT3 LAMA4 NRP1	1.14e-05	179	73	5	e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RFTN1 SLAMF6 RESF1 SEC24A VPS13A	1.14e-05	179	73	5	6bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 NWD2 NKD2 SLIT3 NAV3	1.17e-05	180	73	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Myeloid-Dendritic_cells\|Control / group, cell type (main and fine annotations)	FRMD4A MGAM EMILIN2 ITGAX MFSD1	1.17e-05	180	73	5	25ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLIT3 ABCC9 TMEM100 TMEFF2 NRP1	1.17e-05	180	73	5	b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 NWD2 NKD2 SLIT3 NAV3	1.17e-05	180	73	5	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NKD2 SLIT3 NAV3 LAMA4 ABCC9	1.20e-05	181	73	5	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NKD2 SLIT3 NAV3 LAMA4 ABCC9	1.20e-05	181	73	5	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	MAGI1 MTUS1 USP54 ADGRV1 CDH1	1.20e-05	181	73	5	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 TUSC3 LAMA4 IL6ST NRP1	1.23e-05	182	73	5	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 SLIT3 LAMA4 ABCC9 NRP1	1.23e-05	182	73	5	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAGI1 MTUS1 LAMA4 FLRT2 IL6ST	1.23e-05	182	73	5	53c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RFTN1 SLIT3 LAMA4 ABCC9 NRP1	1.23e-05	182	73	5	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 TUSC3 LAMA4 IL6ST NRP1	1.23e-05	182	73	5	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD34 TUSC3 LAMA4 IL6ST NRP1	1.23e-05	182	73	5	b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAGI1 NAV3 LAMA4 FLRT2 IL6ST	1.27e-05	183	73	5	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD34 SLIT3 LAMA4 TMEM100 TMEFF2	1.27e-05	183	73	5	07ca2786e62eca9feecf5e54a11864a960f7641a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RFTN1 NWD2 SLIT3 MYOM2 FLRT2	1.30e-05	184	73	5	30fddbc9696476d4d7f08e53f84ea994a4ed873a
Drug	irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A	SETD2 TAOK3 DSCAM NFE2L2 SEC24B CDH1 NRP1	1.83e-06	183	72	7	7498_DN
Drug	Rifampicin [13292-46-1]; Up 200; 4.8uM; PC3; HT_HG-U133A	MAGI1 STXBP5L SEC24A ABCC9 FLRT2 TEX15 IL6ST	3.19e-06	199	72	7	4008_UP
Drug	1-alpha-25-dihydroxycholecalciferol	CARM1 MGAM DLGAP1 TAOK3 KRT16 MTUS1 PTPRZ1 TASP1 NAV3 LAMA4 ADGRV1 ITGAX IL6ST	4.80e-06	909	72	13	CID000002524
Disease	Prostatic Neoplasms	CLPTM1L SETD2 NFE2L2 PVR EWSR1 CDH1 IL6ST TMEFF2 NRP1	1.88e-05	616	72	9	C0033578
Disease	Malignant neoplasm of prostate	CLPTM1L SETD2 NFE2L2 PVR EWSR1 CDH1 IL6ST TMEFF2 NRP1	1.88e-05	616	72	9	C0376358
Disease	Eczema	FLG IL6ST	3.51e-05	4	72	2	C0013595
Disease	obsolete_red blood cell distribution width	FRMD4A CLPTM1L BMPR2 TAOK3 RESF1 KANSL1 NKD2 BACH1 VPS13A ZCCHC2 CDH1 ITGAX	9.46e-05	1347	72	12	EFO_0005192
Disease	Adenoid Cystic Carcinoma	MAGI1 SETD2 KANSL1 CDH1	1.07e-04	100	72	4	C0010606
Disease	Helicobacter Infections	PTPRZ1 CDH1	1.22e-04	7	72	2	C0079487
Disease	cytokine measurement	MAGI1 FRMD4A NFE2L2 TUSC3 NAV3 UNC13C FLRT2	1.33e-04	461	72	7	EFO_0004873
Disease	cutaneous melanoma	CLPTM1L BACH2 ADGRV1 CDH1	2.23e-04	121	72	4	EFO_0000389
Disease	Tetralogy of Fallot	MFSD1 NRP1	2.61e-04	10	72	2	HP_0001636
Disease	hemoglobin A1 measurement	MGAM RC3H2 SETD2 TAOK3 VPS13A CDH1 ITGAX	2.78e-04	520	72	7	EFO_0007629
Disease	nucleus accumbens volume change measurement	DSCAM MUC16	3.18e-04	11	72	2	EFO_0021493
Disease	ovarian neoplasm	KANSL1 MUC16 CDH1 IL6ST	3.29e-04	134	72	4	C0919267
Disease	Malignant neoplasm of ovary	KANSL1 MUC16 CDH1 IL6ST	3.58e-04	137	72	4	C1140680
Disease	Endometrial Neoplasms	NFE2L2 ABCC9 CDH1	3.90e-04	58	72	3	C0014170
Disease	information processing speed, response to cranial radiation therapy	FRMD4A DLGAP1 SLIT3	3.90e-04	58	72	3	EFO_0004363, EFO_0010950
Disease	schizophrenia, sex interaction measurement	DSCAM NAV3 RNF111	4.31e-04	60	72	3	EFO_0008343, MONDO_0005090
Disease	Pneumoconiosis	OVGP1 PTPRZ1	5.24e-04	14	72	2	C0032273
Disease	Bagassosis	OVGP1 PTPRZ1	5.24e-04	14	72	2	C0004681
Disease	Alzheimer disease, polygenic risk score	RESF1 KANSL1 CD34 PVR FLRT2 ITGAX NRP1	5.67e-04	586	72	7	EFO_0030082, MONDO_0004975
Disease	Endometrial Carcinoma	NFE2L2 ABCC9 CDH1	7.36e-04	72	72	3	C0476089
Disease	Vitiligo	NFE2L2 BACH2	7.80e-04	17	72	2	C0042900
Disease	hepatocellular carcinoma (is_implicated_in)	TRAF7 CLPTM1L NFE2L2 CDH1	1.02e-03	181	72	4	DOID:684 (is_implicated_in)
Disease	basal cell carcinoma	FRMD4A CLPTM1L BACH2 ADGRV1	1.19e-03	189	72	4	EFO_0004193
Disease	hippocampal sclerosis of aging	TMEM106B ABCC9	1.44e-03	23	72	2	EFO_0005678
Disease	cortical thickness	MAGI1 TMEM106B SLAMF6 KANSL1 SMARCAL1 NAV3 ABCC9 ADGRV1 NRP1	1.51e-03	1113	72	9	EFO_0004840
Disease	Neurodevelopmental Disorders	DLGAP1 SETD2 DSCAM	1.54e-03	93	72	3	C1535926
Disease	indole-3-propionate measurement	SLIT3 UNC13C	1.98e-03	27	72	2	EFO_0010501
Disease	cortical surface area measurement, neuroimaging measurement	MAGI1 SLAMF6 NAV3 NRP1	2.33e-03	227	72	4	EFO_0004346, EFO_0010736
Disease	hepatocellular carcinoma (biomarker_via_orthology)	GMPS CARM1 IL6ST	2.37e-03	108	72	3	DOID:684 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TTATVTTTQASYAAQ	EWSR1	101	Q01844
NSVFAYESSVHSTNV	BACH1	6	O14867
NVYNASSHSTSGFAS	BACH2	241	Q9BYV9
TTTSTNGAAYSNQAV	CTDSPL2	191	Q05D32
LTSAAYQQSLTVHTG	GPS2	111	Q13227
VSISYAVTTGNSTAH	ADGRV1	301	Q8WXG9
TSTVSIQGSGNHYHA	DLGAP1	736	O14490
VLATFVTHAYASGNN	ABCC9	551	O60706
RSGSFLYQVSTHEQS	FLG	1761	P20930
RSGSFLYQVSTHEQS	FLG	2086	P20930
SGSFLYQVSTHEQSE	FLG	2411	P20930
GSFLYQVSTHEQSES	FLG	2736	P20930
RSGSFLYQVSTHEQS	FLG	3706	P20930
EATTHASYLNNGSNT	FLRT2	511	O43155
SSATYINGFTLSANH	NWD2	1056	Q9ULI1
YHTTDPVQATASQGS	RC3H2	916	Q9HBD1
VIPQYHSSVNSAGSS	RFTN1	161	Q14699
LASVHQLQGFTYTAT	ITGAX	216	P20702
SLYVNGFTHQSSVST	MUC16	12341	Q8WXI7
DFNYGSSVASATVHI	TMBIM4	16	Q9HC24
VASNSSHGYPNDTVS	MAGI1	616	Q96QZ7
TSAGVEAAHSQYVTV	SLC2A7	311	Q6PXP3
THSELSTYSNNSGNA	MTUS1	806	Q9ULD2
HVQSFSGNAAASLTY	MGAM	201	O43451
SDVQYNSHGATADIS	MGAM	1006	O43451
GGSTSAHYAVNSQFT	CARM1	571	Q86X55
AARYATQSNHSGIAT	NAV3	226	Q8IVL0
HIQSETSGSANYSQV	NFE2L2	91	Q16236
DVEHTTLYSNNSTAN	KANSL1	216	Q7Z3B3
AHLSSQQASGQSYSS	KRT16	426	P08779
GFSSQAASAINSVVY	MFSD1	296	Q9H3U5
SDNEGSQHIFTVSYS	PTPRZ1	931	P23471
ADTTVSFFHYSQGQV	MPZL1	81	O95297
IYEVVDASVNHSSGS	NKD2	151	Q969F2
IHSDQITASSQYSTN	NRP1	286	O14786
GSQYSTSSQSTFVAH	FRMD4A	956	Q9P2Q2
VHSSYNVATGNIISN	ATMIN	521	O43313
QNTSSTVQYSTVVHS	IL6ST	751	P40189
VINAAHSFYNGTTTL	GMPS	296	P49915
TVANEHRGSQAVSYT	FCGBP	3316	Q9Y6R7
VNSHAATTQYANGTV	BMPR2	816	Q13873
HTGTSNTTFVVYENT	GPR63	11	Q9BZJ6
SVSNASVAQLHTAGY	EMILIN2	971	Q9BXX0
SAYGSTVSNLQHSAL	SEC24B	1051	O95487
TSVITSVYGNTNSSV	CD34	96	P28906
ATYTLFSHAVSSNGN	CDH1	226	P12830
SESLLSQTTGNSNHY	MTBP	756	Q96DY7
YGNHSSVNSVTPQTS	OVGP1	646	Q12889
AASVYSDHTNTNNLT	RNF180	316	Q86T96
QYNDGLSHFVISSVS	LAMA4	1306	Q16363
TVTHTVHYQSVSQAT	DSCAM	1701	O60469
SANGHVSYSAVSREN	PVR	391	P15151
TVTTTYFGHSEQISQ	TMEM106B	231	Q9NUM4
SVSPTNNTVYASVTH	SLAMF6	276	Q96DU3
QNTGHYSSDNTTRAS	TMEFF2	356	Q9UIK5
SHTSVERITYANVNG	RESF1	86	Q9HCM1
VSGNTSLTTNHQYVS	SEC24A	161	O95486
GQNISYIHSSSESVT	SMARCAL1	201	Q9NZC9
GAVYFATNAHTSEVV	TAOK3	36	Q9H2K8
NSSSASQEIGDHQYT	STXBP5L	936	Q9Y2K9
VTNYSVATHVNISFT	HTR3D	56	Q70Z44
SVYTTTRSHLGAENN	CLPTM1L	56	Q96KA5
QQAATSHYSSAQGGS	SS18L1	191	O75177
AQSDSTSYISAVGNT	ZCCHC2	981	Q9C0B9
TVYSVETVNDGQFHS	SLIT3	1226	O75094
VSYIHGSSQAQFVAE	TUSC3	266	Q13454
YSATSGVTTNASHHS	VPS13A	1356	Q96RL7
FYAHTTVSTNIQVSA	UNC13C	1451	Q8NB66
ANSSSGTSYHEQQAL	RNF111	551	Q6ZNA4
QTSGGSVYSIAVTNH	TRAF7	556	Q6Q0C0
SGHTSVSSYQQALGQ	TRBV5-7	46	A0A0A0MS05
VTAVAYSFNSHGSII	TMEM100	71	Q9NV29
SSSQYVAQSDGVVHQ	SETD2	2236	Q9BYW2
TVASTAQGTHSNLLY	TEX15	2696	Q9BXT5
ENTGAHNPYSTAVST	TASP1	276	Q9H6P5
SGFHTYLVASNLTTN	ZDHHC18	296	Q9NUE0
VSHFSSDSQGTVIYN	USP54	411	Q70EL1
TYSAVATNAHGQVST	MYOM2	226	P54296