Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

CRACR2A PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 GRIN1 EFHB ZZEF1 F9 DST RASGRP3 HRC ATP2A2 RHOT1

7.94e-0774913619GO:0005509
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

3.06e-0651363GO:0030156
GeneOntologyMolecularFunctionATP hydrolysis activity

ATP13A1 KIF1B RSF1 MCM6 RAD54L2 KIF3B IQCA1 CCT8 ATP11C ATP2A2 DNAH8

2.21e-0444113611GO:0016887
GeneOntologyBiologicalProcesstransport along microtubule

BICDL2 KIF1B AGBL4 KIF3B DST SUN2 RPGR SPAG17 HSPB1 SOD1 RHOT1

7.28e-0819713511GO:0010970
GeneOntologyBiologicalProcesscytoskeleton-dependent intracellular transport

BICDL2 KIF1B AGBL4 KIF3B DST SUN2 RPGR SPAG17 HSPB1 SOD1 RHOT1

2.79e-0722513511GO:0030705
GeneOntologyBiologicalProcessmicrotubule-based transport

BICDL2 KIF1B AGBL4 KIF3B DST SUN2 RPGR SPAG17 HSPB1 SOD1 RHOT1

8.93e-0725313511GO:0099111
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

4.00e-061871359GO:0007156
GeneOntologyBiologicalProcessaxonal transport

KIF1B AGBL4 KIF3B DST HSPB1 SOD1

9.78e-06751356GO:0098930
GeneOntologyBiologicalProcessretrograde axonal transport

KIF1B AGBL4 DST SOD1

1.68e-05241354GO:0008090
GeneOntologyBiologicalProcessmicrotubule-based process

BICDL2 KIZ KIF1B CKAP5 C10orf90 KIAA1614 AGBL4 KIF3B DST IQCA1 SUN2 CC2D2A RPGR SPAG17 GPSM1 CFAP69 DNAH8 HSPB1 SOD1 RHOT1

1.83e-05105813520GO:0007017
GeneOntologyBiologicalProcessmicrotubule-based movement

BICDL2 KIF1B AGBL4 KIF3B DST SUN2 RPGR SPAG17 CFAP69 DNAH8 HSPB1 SOD1 RHOT1

2.19e-0549313513GO:0007018
GeneOntologyBiologicalProcessaspartate metabolic process

NAT8L ASPA ASS1

2.24e-0591353GO:0006531
GeneOntologyBiologicalProcessanterograde axonal transport

KIF1B AGBL4 KIF3B HSPB1 SOD1

2.98e-05551355GO:0008089
GeneOntologyBiologicalProcessorganelle transport along microtubule

BICDL2 KIF1B AGBL4 KIF3B SUN2 RHOT1

4.27e-05971356GO:0072384
GeneOntologyBiologicalProcessaxo-dendritic transport

KIF1B AGBL4 KIF3B DST HSPB1 SOD1

4.52e-05981356GO:0008088
GeneOntologyBiologicalProcessneuromuscular synaptic transmission

KIF1B RIMBP3 RIMBP3C RIMBP3B

8.79e-05361354GO:0007274
GeneOntologyBiologicalProcessdicarboxylic acid metabolic process

NAT8L MTHFD2 ACLY QPRT ASPA ASS1

9.07e-051111356GO:0043648
GeneOntologyBiologicalProcessnuclear matrix anchoring at nuclear membrane

SYNE1 SUN2

1.27e-0431352GO:0090292
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

2.23e-043131359GO:0098742
GeneOntologyBiologicalProcessinorganic ion homeostasis

SLC12A6 ATP13A1 NT5E CP GRIN1 CCDC115 ITGAV INPP4B BSND HRC FTO ATP2A2 SOD1

2.27e-0462213513GO:0098771
GeneOntologyBiologicalProcessnuclear matrix organization

SYNE1 SUN2

2.53e-0441352GO:0043578
GeneOntologyBiologicalProcessacetate metabolic process

NAT8L ASPA

2.53e-0441352GO:0006083
GeneOntologyCellularComponentneuron projection cytoplasm

KIF1B CKAP5 ADA AGBL4 KIF3B DST HSPB1 SOD1

6.47e-071101378GO:0120111
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

KIF1B CKAP5 EFHB ADA AGBL4 KIF3B DST SPAG17 CFAP69 DNAH8 HSPB1 SOD1

1.23e-0631713712GO:0032838
GeneOntologyCellularComponentcytoplasmic region

KIF1B CKAP5 EFHB ADA AGBL4 KIF3B DST SPAG17 CFAP69 DNAH8 HSPB1 SOD1

4.58e-0636013712GO:0099568
GeneOntologyCellularComponentaxon cytoplasm

KIF1B AGBL4 KIF3B DST HSPB1 SOD1

5.57e-06681376GO:1904115
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C SPAG17 RIMBP3B

3.20e-05281374GO:0002177
GeneOntologyCellularComponentaxonemal central apparatus

SPAG17 CFAP69

6.29e-0461372GO:1990716
MousePhenoectopic manchette

RIMBP3 RIMBP3C RIMBP3B CFAP69

1.64e-05191174MP:0009377
MousePhenoabnormal manchette morphology

RIMBP3 RIMBP3C SPAG17 RIMBP3B CFAP69

3.52e-05451175MP:0009376
DomainCadherin_tail

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

4.03e-12371349PF15974
DomainCadherin_CBD

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

4.03e-12371349IPR031904
DomainCadherin_2

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

8.74e-10651349PF08266
DomainCadherin_N

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

8.74e-10651349IPR013164
DomainCadherin_CS

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

8.94e-081091349IPR020894
DomainCADHERIN_1

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.22e-071131349PS00232
DomainCadherin

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.22e-071131349PF00028
DomainCADHERIN_2

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.32e-071141349PS50268
Domain-

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.32e-0711413492.60.40.60
DomainCA

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.42e-071151349SM00112
DomainCadherin-like

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.53e-071161349IPR015919
DomainCadherin

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.78e-071181349IPR002126
DomainSOD_Cu_Zn_dom

CCS SOD1

1.53e-0431342IPR001424
DomainSOD_CU_ZN_2

CCS SOD1

1.53e-0431342PS00332
DomainSOD_CU_ZN_1

CCS SOD1

1.53e-0431342PS00087
DomainSOD_Cu/Zn_/chaperone

CCS SOD1

1.53e-0431342IPR024134
DomainSOD_Cu/Zn_BS

CCS SOD1

1.53e-0431342IPR018152
DomainSod_Cu

CCS SOD1

1.53e-0431342PF00080
Domain-

CCS SOD1

1.53e-04313422.60.40.200
DomainEFh

CRACR2A EFHB ZZEF1 DST RASGRP3 RHOT1

9.82e-041581346SM00054
Pubmed

Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

9.81e-1915139915640798
Pubmed

Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

4.73e-1817139929911975
Pubmed

CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

9.43e-1818139915570159
Pubmed

Genomic organization of the family of CNR cadherin genes in mice and humans.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

9.43e-1818139910662547
Pubmed

Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

2.49e-1624139924698270
Pubmed

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.30e-1528139915347688
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.53e-1257139932633719
Pubmed

Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4

1.66e-121113969655502
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.80e-1258139930377227
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

8.08e-1268139911230163
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.38e-1172139910380929
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.78e-1174139910817752
Pubmed

The DNA sequence and comparative analysis of human chromosome 5.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

2.01e-1175139915372022
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

2.56e-1177139910835267
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

3.65e-1180139910716726
Pubmed

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.

PCDHA13 PCDHA12 PCDHA8 CP PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 FTO

3.89e-101931391122589738
Pubmed

Proteins of the CNR family are multiple receptors for Reelin.

PCDHA13 PCDHA8 PCDHA7 PCDHA5 PCDHA4

7.34e-1012139510612399
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.33e-09119139928625976
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

UIMC1 MTHFD2 ACLY SYNE1 U2SURP MCM6 GPATCH4 XRCC1 SBSN ARPC2 CSDE1 DST ASS1 CCT8 PPP1R9B C3 LIMCH1 HADHA ATP2A2 HSPB1

1.43e-099491392036574265
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

UIMC1 NCAPD3 ATP13A1 NT5E SYNE1 TASP1 CKAP5 GPATCH4 XRCC1 TRRAP CIT CASZ1 CSDE1 PAXBP1 DST GZF1 RBM19 SUN2 CCT8 LIMCH1 FUT8 ATP2A2 ILVBL EPB41L2

6.20e-0914971392431527615
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

NT5E ACLY U2SURP KIF1B MCM6 GPATCH4 MED13L CIT ARPC2 PAXBP1 SUN2 ASS1 CNDP2 CCT8 LIMCH1 HADHA GMPPB ATP2A2 HSPB1 WWC1 SOD1

2.69e-0812471392127684187
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ACLY SYNE1 WDR81 PCDHA8 CP ZZEF1 ARPC2 ARHGAP1 NBAS DST CNDP2 CCT8 HADHA MYO15A SPAG17 ATP2A2 PCCB

2.71e-088071391730575818
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SLC12A6 DDAH1 ACLY SYNE1 KIF1B CKAP5 GRIN1 CIT ARPC2 CSDE1 AGBL4 DST CCT8 PPP1R9B LIMCH1 HADHA ATP2A2 MTDH HSPB1 EPB41L2 SOD1 RHOT1

6.01e-0814311392237142655
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RASA3 ACLY U2SURP RSF1 CKAP5 MCM6 GPATCH4 TRRAP CSDE1 PCGF6 DST RBM19 ASS1 ZNF638 CCT8 GSDMA HADHA GMPPB ATP2A2 HSPB1 EPB41L2

1.06e-0713531392129467282
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

ACLY CKAP5 LAMB3 CIT ARPC2 CSDE1 ARHGAP1 DST RBM19 SUN2 ASS1 ZNF638 CCT8 GSDMA PPP1R9B C3 HADHA MTDH HSPB1 EPB41L2

1.49e-0712571392036526897
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

2.49e-074139319091768
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

SERPINB7 CKAP5 CP XRCC1 MED13L CIT YOD1 CROCC2 SUN2 ZNF638 CCT8 C3 CCS RBFOX2 RHOT1

2.68e-077321391534732716
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

6.21e-075139317855024
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

CKAP5 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA3 PCDHA2 PCDHA1 XRCC1 CSDE1

9.08e-073291391017474147
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

UIMC1 NCAPD3 U2SURP CKAP5 GPATCH4 XRCC1 TRRAP CASZ1 PCGF6 PAXBP1 DST SUN2 ZNF638 HADHA ATP2A2 MTDH ILVBL HSPB1 RBFOX2

1.04e-0612941391930804502
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

UIMC1 ACLY U2SURP RSF1 CKAP5 GPATCH4 CSDE1 DST ZNF638 CCT8 PPP1R9B BOD1L1 MTDH PKN3 EPB41L2 SOD1

1.12e-069341391633916271
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

SYNE1 DST XIRP2 GPSM1

1.13e-0620139421689717
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SLC12A6 UIMC1 SYNE1 U2SURP RSF1 RAD54L2 INSYN2A ARPC2 DST CC2D2A PPP1R9B ATP11C BOD1L1 LIMCH1 HADHA SPAG17 CFAP69 ATP2A2 DNAH8 MTDH

1.27e-0614421392035575683
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

ACLY CKAP5 GPATCH4 ARPC2 CSDE1 ARHGAP1 PCGF6 RBM19 CCT8 PPP1R9B HADHA ATP2A2 PCCB MTDH

1.35e-067241391436232890
Pubmed

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.

DDAH1 MTHFD2 ACLY ADA ITGAV QPRT ASS1 HADHA ATP2A2 PCCB DNAH8 HSPB1 CCS SOD1 PDZD2

1.96e-068591391531536960
Pubmed

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner.

NCAPD3 NT5E U2SURP CKAP5 PCGF6 XIRP2 SUN2 HSPB1

3.34e-06222139835941108
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ACLY SYNE1 U2SURP CKAP5 MCM6 XRCC1 TRRAP CIT ARPC2 DST ZNF638 CCT8 HADHA ATP2A2 MTDH EPB41L2

3.64e-0610241391624711643
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

NCAPD3 ATP13A1 ACLY SYNE1 U2SURP CKAP5 MCM6 GPATCH4 ARPC2 PAXBP1 RBM19 CCT8 CC2D2A BOD1L1 HADHA ATP2A2 MTDH HSPB1 EPB41L2

4.25e-0614251391930948266
Pubmed

Behavioral impairment in SHATI/NAT8L knockout mice via dysfunction of myelination development.

NAT8L ACLY ASPA

5.16e-069139329203794
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

UIMC1 NCAPD3 RSF1 CKAP5 LAMB3 ZNF407 ITGAV CASZ1 SBSN GZF1 SUN2 FUT8 ATP2A2 MTDH ILVBL HSPB1 SOD1

6.70e-0612031391729180619
Pubmed

TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.

ACLY U2SURP CKAP5 MCM6 CSDE1 HADHA EPB41L2

8.19e-06179139736261009
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

ATP13A1 ACLY KBTBD8 TASP1 GPATCH4 ITGAV SBSN CSDE1 PAXBP1 GZF1 RBM19 CCT8 LIMCH1 HADHA MTDH HSPB1 EPB41L2 SOD1

9.59e-0613711391836244648
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

DDAH1 U2SURP ARPC2 CSDE1 DST HPD CNDP2 CCT8 MTDH PKN3 SOD1

1.15e-055381391128524877
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ACLY U2SURP RSF1 CKAP5 MCM6 TRRAP CSDE1 DST ZNF638 HADHA ATP2A2 EPB41L2

1.32e-056531391222586326
Pubmed

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.

CKAP5 ARPC2 CSDE1 DST CCT8 LIMCH1 ATP2A2 RBFOX2

1.43e-05271139825737280
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

DDAH1 NT5E ACLY CP ITGAV ARPC2 ARHGAP1 KIF3B HPD ASS1 CNDP2 CCT8 MYO15A HSPB1 SOD1

1.46e-0510161391519056867
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

CKAP5 MED13L TRRAP SBSN PCGF6 BOD1L1 STK38L ATP2A2

1.47e-05272139831010829
Pubmed

Solution structure of the second PDZ domain of the neuronal adaptor X11alpha and its interaction with the C-terminal peptide of the human copper chaperone for superoxide dismutase.

CCS SOD1

1.59e-052139216132821
Pubmed

Amyotrophic lateral sclerosis-associated mutant SOD1 inhibits anterograde axonal transport of mitochondria by reducing Miro1 levels.

SOD1 RHOT1

1.59e-052139228973175
Pubmed

CCS and SOD1 mRNA are reduced after copper supplementation in peripheral mononuclear cells of individuals with high serum ceruloplasmin concentration.

CCS SOD1

1.59e-052139217683925
Pubmed

Mutation of superoxide dismutase elevates reactive species: comparison of nitration and oxidation of proteins in different brain regions of transgenic mice with amyotrophic lateral sclerosis.

SLC6A2 SOD1

1.59e-052139217368952
Pubmed

A selenocysteine variant of the human copper chaperone for superoxide dismutase. A Se-XAS probe of cluster composition at the domain 3-domain 3 dimer interface.

CCS SOD1

1.59e-052139218393442
Pubmed

Cu,Zn-superoxide dismutase is lower and copper chaperone CCS is higher in erythrocytes of copper-deficient rats and mice.

CCS SOD1

1.59e-052139215337829
Pubmed

Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions.

CD8B CD8B2

1.59e-05213923035575
Pubmed

Molecular characterization of the murine cytotoxic T-cell membrane glycoprotein Ly-3 (CD8).

CD8B CD8B2

1.59e-05213923498943
Pubmed

Mechanisms for activating Cu- and Zn-containing superoxide dismutase in the absence of the CCS Cu chaperone.

CCS SOD1

1.59e-052139215069187
Pubmed

A molecular chaperone activity of CCS restores the maturation of SOD1 fALS mutants.

CCS SOD1

1.59e-052139229234142
Pubmed

An immunological role for the CD8 beta-chain.

CD8B CD8B2

1.59e-05213921534146
Pubmed

Ablating N-acetylaspartate prevents leukodystrophy in a Canavan disease model.

NAT8L ASPA

1.59e-052139225712859
Pubmed

Duality of the murine CD8 compartment.

CD8B CD8B2

1.59e-052139224594598
Pubmed

Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain.

CD8B CD8B2

1.59e-05213927889415
Pubmed

AKXD recombinant inbred strains: models for studying the molecular genetic basis of murine lymphomas.

CD8B CD8B2

1.59e-05213923025647
Pubmed

Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenic determinants.

CD8B CD8B2

1.59e-05213922452747
Pubmed

Distinct methylation states of the CD8 beta gene in peripheral T cells and intraepithelial lymphocytes.

CD8B CD8B2

1.59e-05213929233619
Pubmed

Stalk region of beta-chain enhances the coreceptor function of CD8.

CD8B CD8B2

1.59e-052139212847256
Pubmed

Structural and biophysical properties of the pathogenic SOD1 variant H46R/H48Q.

CCS SOD1

1.59e-052139219227972
Pubmed

Suppressing N-Acetyl-l-Aspartate Synthesis Prevents Loss of Neurons in a Murine Model of Canavan Leukodystrophy.

NAT8L ASPA

1.59e-052139228077719
Pubmed

Regional Differences in Heat Shock Protein 25 Expression in Brain and Spinal Cord Astrocytes of Wild-Type and SOD1 G93A Mice.

HSPB1 SOD1

1.59e-052139234069691
Pubmed

Transcriptional diversity at the duplicated human CD8 beta loci.

CD8B CD8B2

1.59e-05213928436166
Pubmed

Isolated cytochrome c oxidase deficiency in G93A SOD1 mice overexpressing CCS protein.

CCS SOD1

1.59e-052139218334481
Pubmed

Crystal structure of the second domain of the human copper chaperone for superoxide dismutase.

CCS SOD1

1.59e-052139210677207
Pubmed

The copper chaperone CCS directly interacts with copper/zinc superoxide dismutase.

CCS SOD1

1.59e-05213929726962
Pubmed

Structure and expression of the Lyt-3a gene of C.AKR mice.

CD8B CD8B2

1.59e-05213923169881
Pubmed

Free copper, ferroxidase and SOD1 activities, lipid peroxidation and NO(x) content in the CSF. A different marker profile in four neurodegenerative diseases.

CP SOD1

1.59e-052139218307039
Pubmed

Esr, a second locus in the house mouse controlling esterase-5.

CD8B CD8B2

1.59e-05213927103930
Pubmed

Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis.

CCS SOD1

1.59e-052139218552350
Pubmed

Copper, zinc-superoxide dismutase protein but not mRNA is lower in copper-deficient mice and mice lacking the copper chaperone for superoxide dismutase.

CCS SOD1

1.59e-052139212968068
Pubmed

Transient limb ischemia alters serum protein expression in healthy volunteers: complement C3 and vitronectin may be involved in organ protection induced by remote ischemic preconditioning.

ITGAV C3

1.59e-052139224363825
Pubmed

Redox susceptibility of SOD1 mutants is associated with the differential response to CCS over-expression in vivo.

CCS SOD1

1.59e-052139219320055
Pubmed

Transduced HSP27 protein protects neuronal cell death by enhancing FALS-associated SOD1 mutant activity.

HSPB1 SOD1

1.59e-052139219335999
Pubmed

Ly-C: a third locus specifying alloantigens expressed only on thymocytes and lymphocytes.

CD8B CD8B2

1.59e-05213925558567
Pubmed

Human superoxide dismutase 1 (hSOD1) maturation through interaction with human copper chaperone for SOD1 (hCCS).

CCS SOD1

1.59e-052139222869735
Pubmed

Pharmacogenetics and obesity: common gene variants influence weight loss response of the norepinephrine/dopamine transporter inhibitor GW320659 in obese subjects.

GRIN1 SLC6A2

1.59e-052139216272960
Pubmed

N-Acetylaspartate Synthase Deficiency Corrects the Myelin Phenotype in a Canavan Disease Mouse Model But Does Not Affect Survival Time.

NAT8L ASPA

1.59e-052139226511242
Pubmed

Cloning and modeling of CD8 beta in the amphibian ambystoma Mexicanum. Evolutionary conserved structures for interactions with major histocompatibility complex (MHC) class I molecules.

CD8B CD8B2

1.59e-052139212034498
Pubmed

Biological effects of CCS in the absence of SOD1 enzyme activation: implications for disease in a mouse model for ALS.

CCS SOD1

1.59e-052139218337307
Pubmed

Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.

CD8B CD8B2

1.59e-05213928108731
Pubmed

Murine Ly-3 restriction fragment length polymorphism and transcript size differences.

CD8B CD8B2

1.59e-05213922576243
Pubmed

In-cell NMR reveals potential precursor of toxic species from SOD1 fALS mutants.

CCS SOD1

1.59e-052139225429517
Pubmed

Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading.

CCS SOD1

1.59e-052139211889469
Pubmed

The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development.

CD8B CD8B2

1.59e-05213929647223
Pubmed

Mutations in Superoxide Dismutase 1 (Sod1) Linked to Familial Amyotrophic Lateral Sclerosis Can Disrupt High-Affinity Zinc-Binding Promoted by the Copper Chaperone for Sod1 (Ccs).

CCS SOD1

1.59e-052139232121118
Pubmed

Effect of CCS on the accumulation of FALS SOD1 mutant-containing aggregates and on mitochondrial translocation of SOD1 mutants: implication of a free radical hypothesis.

CCS SOD1

1.59e-052139221354101
Pubmed

The IB-peptide marker and the Ly-3 surface alloantigen: structural studies of a V kappa-region polymorphism and a T-cell marker determined by linked genes.

CD8B CD8B2

1.59e-0521392408079
Pubmed

Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS.

CCS SOD1

1.59e-052139230735496
Pubmed

Characterization of the mouse CD8 beta chain-encoding gene promoter region.

CD8B CD8B2

1.59e-05213928781121
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

SERPINB7 UIMC1 KIF1B CKAP5 LAMB3 XRCC1 LIMS3 INPP4B CSDE1 DST QPRT ZNF638 CCT8 C3 RPGR TNXB HSPB1

1.70e-0512931391715342556
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

ACLY U2SURP GPATCH4 ITGAV TRRAP CSDE1 ARHGAP1 DST ASS1 CCT8 C3 BOD1L1 HADHA ATP2A2 ILVBL HSPB1 EPB41L2

1.77e-0512971391733545068
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

SERPINB7 DDAH1 CCT8 CC2D2A GSDMA C3 HADHA MYO15A ATP2A2 HSPB1 SOD1

1.78e-055641391121565611
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

2.20e-0514139317662146
InteractionPCDHA10 interactions

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2

1.03e-12221368int:PCDHA10
InteractionPCDHA8 interactions

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA4 PCDHA3 PCDHA2 PCDHA1 FUT8

1.09e-10551369int:PCDHA8
InteractionPCDHA7 interactions

PCDHA12 PCDHA8 PCDHA7 PCDHA4 PCDHA2

2.48e-08141365int:PCDHA7
InteractionPCDHA1 interactions

PCDHA8 PCDHA4 PCDHA3 PCDHA1

2.44e-0791364int:PCDHA1
InteractionPCDHA11 interactions

PCDHA12 PCDHA4 PCDHA3 PCDHA1

7.11e-06191364int:PCDHA11
InteractionPCDHA6 interactions

PCDHA8 PCDHA3 CIT

2.45e-0591363int:PCDHA6
InteractionGOT1 interactions

SERPINB7 SBSN ARHGAP1 YOD1 CCT8 GSDMA PPP1R9B C3 CCS SOD1

2.50e-0528613610int:GOT1
InteractionKIFBP interactions

U2SURP KIF1B CIT KIF3B ZNF638 BOD1L1 HADHA PLD2

3.09e-051801368int:KIFBP
InteractionEED interactions

NCAPD3 ACLY CKAP5 MCM6 XRCC1 TRRAP CIT CASZ1 ARPC2 ARHGAP1 PCGF6 XIRP2 RBM19 SUN2 CNDP2 ZNF638 CCT8 PPP1R9B LIMCH1 HADHA FTO ATP2A2 PCCB RHOT1

3.44e-05144513624int:EED
InteractionPCDHA4 interactions

PCDHA12 PCDHA8 PCDHA7 PCDHA4 PCDHA1

5.27e-05601365int:PCDHA4
InteractionAGR2 interactions

ACLY SYNE1 WDR81 PCDHA8 CP ZZEF1 ARPC2 ARHGAP1 NBAS DST CNDP2 CCT8 C3 HADHA MYO15A SPAG17 ATP2A2 PCCB

5.79e-0593413618int:AGR2
InteractionFLT3 interactions

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 TRRAP

6.11e-0531813610int:FLT3
InteractionLONP2 interactions

PCDHA12 PCDHA8 PCDHA4 PCDHA3 WWC1

6.18e-05621365int:LONP2
InteractionTNIP1 interactions

UIMC1 MTHFD2 ACLY SYNE1 U2SURP MCM6 GPATCH4 XRCC1 SBSN ARPC2 CSDE1 DST ASS1 CCT8 GSDMA PPP1R9B C3 LIMCH1 HADHA ATP2A2 HSPB1

6.61e-05121713621int:TNIP1
InteractionPCDHA2 interactions

PCDHA8 PCDHA7 PCDHA2

1.04e-04141363int:PCDHA2
InteractionNAA40 interactions

UIMC1 ACLY U2SURP RSF1 CKAP5 GPATCH4 CIT CSDE1 DST ZNF638 CCT8 PPP1R9B BOD1L1 LIMCH1 MTDH PKN3 EPB41L2 SOD1

1.04e-0497813618int:NAA40
Cytoband5q31

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

8.81e-1111513995q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

3.55e-072981399chr5q31
Cytoband12q24.21

MED13L RBM19

9.05e-055139212q24.21
Cytoband10q26.2

C10orf90 INSYN2A

5.89e-0412139210q26.2
GeneFamilyClustered protocadherins

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

1.04e-116481920
GeneFamilyLIM zinc finger domain containing|LIM domain containing

LIMS4 LIMS3

1.18e-0448121163
GeneFamilyEF-hand domain containing

CRACR2A EFHB ZZEF1 DST RASGRP3 RHOT1

4.49e-04219816863
GeneFamilyLIM domain containing

LIMS3 XIRP2 LIMCH1

2.35e-03598131218
CoexpressionGSE8621_LPS_PRIMED_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN

NCAPD3 ACLY KIF1B KBTBD8 TASP1 CIT DHDH RPGR GPSM1

1.20e-062001389M6975
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 DHDH

1.31e-0626113810MM1277
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

PCDHA13 PCDHA12 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 DHDH

5.01e-062381389M2020
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

U2SURP CKAP5 MED13L TRRAP DST ZNF638 LIMCH1 RPGR FTO FUT8 WWC1 RBFOX2

6.98e-0646613812M13522
CoexpressionGSE14308_TH17_VS_NATURAL_TREG_DN

BICDL2 UIMC1 ACLY ZZEF1 ZNF638 DNAH8 EPB41L2 RHOT1

1.14e-052001388M3390
CoexpressionGSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP

SLC12A6 SERPINB7 UIMC1 IL31RA RASA3 PAXBP1 SUN2 BOD1L1

1.14e-052001388M6477
CoexpressionGRYDER_PAX3FOXO1_ENHANCERS_IN_TADS

RASA3 ACLY KBTBD8 LAMB3 MED13L ZZEF1 KIAA1614 INPP4B ARPC2 ASS1 LIMCH1 ADAMTS14 FTO ATP2A2 PCCB SOD1

8.51e-05100913816M157
CoexpressionGSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP

ITFG2 TASP1 ZNF407 MED13L NBAS FUT8 TANGO6

8.60e-051971387M7403
CoexpressionGSE28726_NAIVE_VS_ACTIVATED_NKTCELL_UP

SERPINB7 RASA3 ADA CIT LFNG SUN2 RBFOX2

9.16e-051991387M8318
CoexpressionHALLMARK_MITOTIC_SPINDLE

KIF1B CKAP5 KIF3B DST SUN2 STK38L EPB41L2

9.16e-051991387M5893
CoexpressionGSE40273_XBP1_KO_VS_WT_TREG_DN

NCAPD3 MORN1 NT5E SYNE1 LRRK1 TRRAP PLD2

9.16e-051991387M9124
CoexpressionGSE21670_IL6_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_DN

IL31RA NT5E MCM6 BSND ASS1 LIMCH1 CFAP69

9.45e-052001387M7473
CoexpressionGSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN

SLC12A6 RASA3 MED13L C17orf58 GZF1 DNAH8 PDZD2

9.45e-052001387M8956
CoexpressionGSE22886_DC_VS_MONOCYTE_UP

MCM6 QPRT RASGRP3 PCCB ILVBL HSPB1 EPB41L2

9.45e-052001387M4471
CoexpressionGRYDER_PAX3FOXO1_ENHANCERS_KO_DOWN

KBTBD8 LAMB3 KIAA1614 ARPC2 ASS1 LIMCH1 ADAMTS14 ATP2A2 PCCB SOD1

1.13e-0443813810M227
CoexpressionGRYDER_PAX3FOXO1_TOP_ENHANCERS

RASA3 LAMB3 MED13L ZZEF1 KIAA1614 INPP4B ARPC2 ASS1 LIMCH1 ADAMTS14

1.20e-0444113810M172
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

PCDHA8 CP PCDHA7 PCDHA3 MED13L KIAA1614 C17orf58 CD8B LIMCH1

2.36e-091631399f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

BICDL2 NT5E CP INPP4B IQCA1 MACROD2 LIMCH1 WWC1

1.87e-071951398dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NT5E CP CIT INPP4B IQCA1 KCNC3 MACROD2 WWC1

2.10e-071981398af399569c718f5fd971d73a7926768c9311002a3
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NT5E CP CIT INPP4B IQCA1 KCNC3 MACROD2 WWC1

2.10e-0719813981408e02e053ad3406229bfe8189da03be6366e81
ToppCellASK452-Epithelial|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

LAMB3 CP DST C3 LIMCH1 SPAG17 HSPB1 WWC1

2.18e-071991398e8778d4d2bc7e15b4c7989a93e5808a76738df46
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF407 MED13L NBAS MACROD2 LIMCH1 FTO FUT8 RBFOX2

2.18e-07199139894b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCAPD3 NT5E CP ZNF407 INPP4B CD8B CD8B2

7.57e-0716113975fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellfacs-Spleen-nan-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NT5E MTHFD2 TASP1 LFNG INPP4B DST ASS1

1.72e-061821397fbe5bdd642b86010dbef0a567b25c69c7335688f
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

DDAH1 CP CIT MACROD2 LIMCH1 FUT8 WWC1

2.06e-06187139781cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMB3 CP PAXBP1 IQCA1 C3 LIMCH1 WWC1

2.06e-06187139758d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB7 LAMB3 LRRK1 KIAA1614 ATP2A2 RBFOX2 TANGO6

2.06e-061871397a6a112689d1c9049f57935ad9d2f4955538427de
ToppCellfacs-Skin-nan-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINB7 COL16A1 RASA3 SYNE1 SLC6A2 ARHGAP1 LIMCH1

2.21e-0618913976c71e81373cb7822de23c193a6350b6df9f567bc
ToppCellSupraBC-Differ-KC|World / shred by cell class for mouse tongue

BICDL2 SERPINB7 NAT8L SBSN GSDMA HSPB1 EPB41L2

2.21e-0618913976412741b88e241304033b41effca0c77a374d907
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MORN1 SYNE1 EFHB AGBL4 CROCC2 SPAG17 CFAP69

2.62e-0619413974a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY PCDHA8 GRIN1 ITGAV DST GPSM1 ATP2A2

2.72e-061951397bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL16A1 SYNE1 DST LIMCH1 CFAP69 TNXB EPB41L2

2.90e-061971397fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF407 MED13L MACROD2 LIMCH1 FTO RBFOX2 PDZD2

3.00e-0619813971996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

COL16A1 RASA3 SYNE1 C3 LIMCH1 CFAP69 TNXB

3.10e-0619913978b86c69aaf60feff53aa782559cfece7342a23de
ToppCelldistal-Epithelial|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BICDL2 DDAH1 LAMB3 CP C3 LIMCH1 WWC1

3.21e-0620013970a97080f694738bb882787cee21b91a4d5757b7a
ToppCellmedial-2-Epithelial|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BICDL2 LAMB3 CP MACROD2 C3 SPAG17 WWC1

3.21e-0620013970079041c3e654c1ef77c492bdb2f31ce8f4b507b
ToppCellmedial-Epithelial|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BICDL2 LAMB3 CP MACROD2 C3 SPAG17 WWC1

3.21e-06200139717bb9a9016058cbb70c7bd894c12f6208ff07895
ToppCellASK440-Epithelial|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

SYNE1 LAMB3 CP C3 LIMCH1 SPAG17 WWC1

3.21e-062001397cb617e2a0ca82b470b473b8d5906bc8879c85718
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRRC63 AGBL4 CROCC2 FTO SPAG17 CFAP69

1.53e-051691396fba841664939c771881ba97f14ef1df6635c04ff
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

BICDL2 CRACR2A ATP13A1 MED13L TRRAP LIMCH1

1.69e-051721396da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

BICDL2 CP CIT MACROD2 LIMCH1 FUT8

1.92e-0517613963fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NCAPD3 CRACR2A RAD54L2 KCNC3 PPP1R9B ATP2A2

1.98e-051771396e1e45956887371b1c18f1eb479dd930031497520
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CIT IQCA1 MACROD2 LIMCH1 FUT8 WWC1

2.05e-051781396f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

LAMB3 CASZ1 MACROD2 LIMCH1 WWC1 PDZD2

2.11e-051791396a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCellfacs-Spleen-nan-3m-Lymphocytic-Cd3e_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF1B LFNG INPP4B CD8B SUN2 ASS1

2.25e-051811396be7c7db6b99603759593e6f79cdcaa4bbf234cb7
ToppCellfacs-Spleen-nan-18m-Lymphocytic-Cd3e_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NT5E MTHFD2 TASP1 LFNG INPP4B ASS1

2.32e-051821396da3e9093cba791c7c282eb044656046252a32789
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMB3 CP PAXBP1 C3 LIMCH1 WWC1

2.47e-05184139642ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF1B LFNG INPP4B ARHGAP1 SUN2 ASS1

2.47e-051841396c37c623c4a5ff1628486d8a6461fa355ad5c264c
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

ITGAV INPP4B DST XIRP2 LIMCH1 PDZD2

2.47e-051841396ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMB3 CP PAXBP1 C3 LIMCH1 WWC1

2.54e-0518513960d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

DDAH1 CIT MACROD2 LIMCH1 FUT8 WWC1

2.54e-05185139698b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY LFNG INPP4B CSDE1 PAXBP1 SUN2

2.54e-051851396a2cae8c657e4f4d121476798e424876f7e247973
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY LFNG INPP4B CSDE1 PAXBP1 SUN2

2.54e-051851396d50406a9a5b8d75110ba5985741aa2293950c543
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPINB7 SBSN QPRT C3 LIMCH1 TNXB

2.70e-0518713960d4b7da81036c2aa678654b9fe49c939d08fcd9b
ToppCellClub-club-14|World / Class top

CP C17orf58 C3 FUT8 WWC1 SOD1

2.70e-0518713964584de577d3736c89187e522497498e58d381c46
ToppCellfacs-Tongue-nan-24m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BICDL2 SERPINB7 NAT8L SBSN GSDMA EPB41L2

2.78e-051881396ed35e438796cef302b6787c111753425922792dc
ToppCellfacs-Lung-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAT8L CP C17orf58 C3 LIMCH1 TNXB

2.87e-051891396bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAT8L CP C17orf58 C3 LIMCH1 TNXB

2.87e-05189139640cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RASA3 LRRK1 C3 CFAP69 TNXB EPB41L2

2.95e-0519013960fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

CASZ1 DST LIMCH1 GPSM1 ATP2A2 PDZD2

2.95e-051901396fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8L CP C17orf58 LIMCH1 TNXB HSPB1

3.04e-051911396a261f0738d974784bbdd60f23092bfbcca464459
ToppCellCOPD-Epithelial-Club|COPD / Disease state, Lineage and Cell class

BICDL2 CP ASS1 MACROD2 LIMCH1 WWC1

3.04e-051911396c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8L CP C17orf58 LIMCH1 TNXB HSPB1

3.04e-0519113966594398cc8151c73696391a43ac110c10283dab1
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAT8L CP C17orf58 LIMCH1 TNXB HSPB1

3.04e-051911396d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAT8L CP C17orf58 LIMCH1 TNXB HSPB1

3.04e-051911396de3e9b704621b26836c2ddc39fa3e840dfb4541b
ToppCell(12)_SLC16A7+|World / shred by cell type by condition

KIAA1614 LIMS3 QPRT SPAG17 NPIPA2 CFAP69

3.04e-051911396e427eeddd2e87c14376a37db0b43f120c90436bc
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

BICDL2 MACROD2 LIMCH1 SPAG17 CFAP69 WWC1

3.13e-0519213960644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

DDAH1 MACROD2 LIMCH1 WWC1 RBFOX2 PDZD2

3.13e-051921396efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8L CP C17orf58 C3 LIMCH1 TNXB

3.13e-0519213965876ff75e273a48e7ad8236423fb41e4ae4c0a91
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CP EFHB IQCA1 CC2D2A FTO SPAG17

3.22e-051931396c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY ARHGAP1 HPD FUT8 STK38L GPSM1

3.22e-0519313965a92697430f16c49e19a5f727d289d7bd1ece31c
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY ARHGAP1 HPD FUT8 STK38L GPSM1

3.22e-05193139664bcdbb422f8da6fc3275e82f6aaf562f546a180
ToppCelldroplet-Tongue-Unstain-18m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BICDL2 SERPINB7 NAT8L SBSN HSPB1 EPB41L2

3.22e-051931396f074ebf9c5c53d8589d66b0109505f30baa1af81
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BICDL2 SERPINB7 NAT8L SBSN HSPB1 EPB41L2

3.32e-051941396a3adcdc8b87332e8beb9bcd70cf36424af10633d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SYNE1 CIT CASZ1 MACROD2 LIMCH1 PDZD2

3.32e-05194139697534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellASK452-Epithelial-Ciliated|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CP EFHB IQCA1 CC2D2A FTO SPAG17

3.32e-0519413965aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

SYNE1 AGBL4 LIMCH1 SPAG17 CFAP69 WWC1

3.42e-051951396fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

AGBL4 CROCC2 LIMCH1 SPAG17 CFAP69 WWC1

3.42e-05195139621dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCAPD3 MCM6 GPATCH4 ADA CIT CD8B

3.42e-051951396be8db0a22ef8ce24819f790b0bd93670e73af76f
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

CASZ1 INPP4B DST XIRP2 MACROD2 ATP2A2

3.42e-05195139675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

COL16A1 INPP4B DST ASPA GPSM1 TNXB

3.42e-05195139661c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GRIN1 DST KCNC3 LIMCH1 STK38L EPB41L2

3.42e-0519513964cbc36fb3ef9aef61367d3b37070a9a85fae1418
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

SYNE1 AGBL4 LIMCH1 SPAG17 CFAP69 WWC1

3.42e-051951396eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SERPINB7 CP CASZ1 MACROD2 LIMCH1 WWC1

3.42e-051951396e7230a849ea31e6eef9bc6f5468938499450582d
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTHFD2 ACLY GRIN1 GMPPB GPSM1 ATP2A2

3.42e-05195139658b769da05a8f6b05aeb08d4f8b112941087ad00
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF407 MED13L MACROD2 LIMCH1 RBFOX2 PDZD2

3.52e-051961396ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE1 AGBL4 LIMCH1 SPAG17 CFAP69 WWC1

3.52e-051961396af4cdc61830685a888a1209826c23bcf54a43084
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RASA3 NDUFAF2 KBTBD8 ADA ITGAV MTDH

3.52e-05196139680264c2fbd94418f981085fed7c5bdda1e6f404c
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE1 AGBL4 LIMCH1 SPAG17 CFAP69 WWC1

3.52e-0519613966d02d494196e3f857d53eea46d9419690d43beca
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

AGBL4 CROCC2 LIMCH1 SPAG17 CFAP69 WWC1

3.52e-05196139687d9881cfec461a5d89b688a83749b618c519485
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

BICDL2 NT5E LAMB3 CP C3 WWC1

3.62e-05197139644a59dfb889577b3160a5b13ada1276771a00241
ToppCellT_cells-CTLs|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

RASA3 SYNE1 CASZ1 ARPC2 CD8B SUN2

3.62e-05197139628117cf300e169182571fbad0de1681a484a435a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DDAH1 COL16A1 RASA3 SYNE1 INPP4B EPB41L2

3.62e-0519713969b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellControl_saline-Epithelial_alveolar-AT_2-AT2|Control_saline / Treatment groups by lineage, cell group, cell type

DDAH1 NT5E LAMB3 CP C3 WWC1

3.62e-051971396f870a26f322668781e3d2832c5d9ef2c7c91011f
ToppCellEpithelial_cells-Epithelial_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

DDAH1 HPD QPRT ASPA ASS1 WWC1

3.72e-05198139652e9d41a1726bc1140df6baec9f17a534448ac8b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DDAH1 COL16A1 RASA3 SYNE1 INPP4B EPB41L2

3.72e-051981396a860246bcea847249a78fd2e86ed8e04371060db
ToppCelldistal-Epithelial-Club-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BICDL2 LAMB3 CP ASS1 MACROD2 C3

3.72e-05198139677c7fa7626ea35cb50de9c2f2df637d22e77d3fe
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NT5E LAMB3 INPP4B ASS1 C3 HSPB1

3.72e-051981396270cecff42b87b7e03f09dd9f99547b287b4598c
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

DDAH1 COL16A1 NT5E SYNE1 SBSN HSPB1

3.72e-0519813969f9dcf23ffb333105263132d87b90095642294cf
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NT5E LAMB3 INPP4B ASS1 C3 HSPB1

3.72e-0519813968b3f4effaaccf8777cde854d5d8a765962f7312b
ToppCellEpithelial_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

DDAH1 HPD QPRT ASPA ASS1 WWC1

3.72e-051981396eeec789d226171f30799577cc37c07bdced2e3cb
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

RSF1 C17orf58 SLC6A2 BOD1L1 RPGR SPAG17

3.83e-05199139661b1ed2db71b96157b92b7535d1955a4033098da
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Transitional_AT2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DDAH1 LAMB3 CP MACROD2 LIMCH1 WWC1

3.83e-051991396b44d74895846e2ac144438b73e0ca91e3949c16c
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Transitional_AT2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DDAH1 LAMB3 CP MACROD2 LIMCH1 WWC1

3.83e-0519913964b374a5de82b4614d3d8a00202ea6cb8f1fd8104
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

COL16A1 SYNE1 CP DST LIMCH1 TNXB

3.83e-051991396a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCelllymphoid-T_cell-CD8+_Naive_T_cell|lymphoid / Lineage, cell class and subclass

NT5E ARPC2 CSDE1 CD8B SUN2 CCT8

3.83e-05199139622926327c93ede9f3408c99a0d56e373a33240ef
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Transitional_AT2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

DDAH1 LAMB3 CP MACROD2 LIMCH1 WWC1

3.83e-0519913969e8231c9007d8d963805a4c99e0905538ceb9b60
ToppCelltumor_Lung-Epithelial_cells|tumor_Lung / Location, Cell class and cell subclass

BICDL2 DDAH1 LAMB3 CP ASS1 HSPB1

3.83e-05199139656b3f6c8b561d60780d91daf6b44a9dcf616e599
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL16A1 SYNE1 DST LIMCH1 TNXB EPB41L2

3.83e-05199139630d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL16A1 SYNE1 DST LIMCH1 TNXB EPB41L2

3.93e-0520013969b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellmetastatic_Lymph_Node-Epithelial_cells-Malignant_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

DDAH1 LAMB3 CP ASS1 LIMCH1 RBFOX2

3.93e-0520013965e2def2e56f21bc7295cdcf3580f5c0d16a6a494
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

SYNE1 EFHB CC2D2A RPGR SPAG17 CFAP69

3.93e-0520013963305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellBiopsy_Other_PF-Epithelial|Biopsy_Other_PF / Sample group, Lineage and Cell type

LAMB3 CP MACROD2 C3 LIMCH1 WWC1

3.93e-0520013961ef4d5ae698fa721e0f510bf0d918bd8d3b00591
ToppCelldistal-2-Epithelial|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BICDL2 LAMB3 CP C3 SPAG17 WWC1

3.93e-0520013962fc1e95706f212bf18ecdf6eb5b3182ac98c9b52
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL16A1 SYNE1 DST QPRT LIMCH1 TNXB

3.93e-05200139644a68bacdb3d5bf563bd35952176995850933a81
ToppCellcontrol-cDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LRRK1 DST KCNC3 LIMCH1 STK38L EPB41L2

3.93e-0520013964a6d17a4225be38537d3dd8a39512051f597f4e0
Disease1,5 anhydroglucitol measurement

PCDHA13 PCDHA12 PCDHA8 PCDHA7 MCM6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

3.91e-172913110EFO_0008009
Diseasevisceral adipose tissue measurement, body mass index

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 NBAS

6.29e-128713110EFO_0004340, EFO_0004765
Diseasepost-traumatic stress disorder symptom measurement

SYNE1 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 MACROD2

1.13e-10821319EFO_0008535
Diseaseneutrophil count, basophil count

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

7.56e-072241319EFO_0004833, EFO_0005090
Diseaseneutrophil count

ATP13A1 KIF1B PCDHA13 PCDHA12 PCDHA8 PCDHA7 MCM6 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 VWA7 CIT CASZ1 ARPC2 GSDMA FTO STK38L TNXB PKN3

7.84e-07138213121EFO_0004833
Diseasevital capacity

SYNE1 PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 ZZEF1 CASZ1 DST CROCC2 ATP2A2 TNXB EPB41L2 PDZD2

9.36e-06123613118EFO_0004312
Diseasetype 2 diabetes mellitus (is_marker_for)

CP ADA F9 FTO RBFOX2 SOD1

3.35e-051361316DOID:9352 (is_marker_for)
Diseasepost-traumatic stress disorder

PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1

3.46e-052021317EFO_0001358
Diseaseneuroticism measurement, cognitive function measurement

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 ZNF638 FTO

4.68e-0556613111EFO_0007660, EFO_0008354
Diseasecortical surface area measurement

NCAPD3 DDAH1 NDUFAF2 KIF1B MED13L KIAA1614 C17orf58 ARHGAP1 PCGF6 MACROD2 PPP1R9B SPAG17 TNXB WWC1 RHOT1 TANGO6 PDZD2

9.85e-05134513117EFO_0010736
DiseaseRetinal Degeneration

CP RPGR SOD1

1.07e-04211313C0035304
DiseaseHepatitis, Chronic

CP CCS SOD1

1.24e-04221313C0019189
DiseaseChronic active hepatitis

CP CCS SOD1

1.24e-04221313C0520463
DiseaseChronic Persistent Hepatitis

CP CCS SOD1

1.24e-04221313C0149519
DiseaseCryptogenic Chronic Hepatitis

CP CCS SOD1

1.24e-04221313C0524611
DiseaseDrug habituation

SYNE1 AGBL4 MACROD2 LIMCH1 DNAH8

1.66e-041151315C0013170
DiseaseDrug abuse

SYNE1 AGBL4 MACROD2 LIMCH1 DNAH8

1.66e-041151315C0013146
DiseasePrescription Drug Abuse

SYNE1 AGBL4 MACROD2 LIMCH1 DNAH8

1.66e-041151315C4316881
DiseaseSubstance-Related Disorders

SYNE1 AGBL4 MACROD2 LIMCH1 DNAH8

1.66e-041151315C0236969
DiseaseDrug Use Disorders

SYNE1 AGBL4 MACROD2 LIMCH1 DNAH8

1.66e-041151315C0013222
DiseaseDrug Dependence

SYNE1 AGBL4 MACROD2 LIMCH1 DNAH8

1.66e-041151315C1510472
DiseaseSubstance Dependence

SYNE1 AGBL4 MACROD2 LIMCH1 DNAH8

1.66e-041151315C0038580
DiseaseSubstance Use Disorders

SYNE1 AGBL4 MACROD2 LIMCH1 DNAH8

1.66e-041151315C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

SYNE1 AGBL4 MACROD2 LIMCH1 DNAH8

1.66e-041151315C0029231
DiseaseSubstance abuse problem

SYNE1 AGBL4 MACROD2 LIMCH1 DNAH8

1.73e-041161315C0740858
Diseasehypertension (is_implicated_in)

DDAH1 SLC6A2 RASGRP3 FTO SOD1

2.10e-041211315DOID:10763 (is_implicated_in)
DiseaseAbnormality of refraction

PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 ZZEF1 CNDP2

2.14e-0467313111HP_0000539
DiseaseInvoluntary Movements

CP GRIN1

4.05e-0471312C0427086
Diseasepulse pressure measurement

DDAH1 CKAP5 PCDHA13 PCDHA12 PCDHA8 PCDHA7 PCDHA5 PCDHA4 PCDHA3 PCDHA2 PCDHA1 MED13L CASZ1 ZNF638 FTO CFAP69

4.60e-04139213116EFO_0005763
DiseaseModerate albuminuria, diabetic nephropathy

FTO WWC1

5.38e-0481312EFO_0000401, HP_0012594
Diseaseinfection

RSF1 MACROD2

6.90e-0491312EFO_0000544
Diseaseretinitis pigmentosa (is_implicated_in)

CC2D2A RPGR SOD1

8.06e-04411313DOID:10584 (is_implicated_in)
DiseaseCarotid Circulation Transient Ischemic Attack

C3 SOD1

8.60e-04101312C0751019
DiseaseTransient Ischemic Attack

C3 SOD1

8.60e-04101312C0007787
DiseaseCrescendo Transient Ischemic Attacks

C3 SOD1

8.60e-04101312C0751021
DiseaseTransient Ischemic Attack, Vertebrobasilar Circulation

C3 SOD1

8.60e-04101312C0751020
DiseaseBrain Stem Ischemia, Transient

C3 SOD1

8.60e-04101312C0751022
DiseasePosterior Circulation Transient Ischemic Attack

C3 SOD1

8.60e-04101312C0472381
DiseaseTransient Ischemic Attack, Anterior Circulation

C3 SOD1

8.60e-04101312C1527335
DiseaseTransient Cerebral Ischemia

C3 SOD1

8.60e-04101312C0917805
Diseasehearing impairment

BSND RPGR MYO15A SOD1

9.71e-04981314C1384666
Diseasemyeloid white cell count

RASA3 ATP13A1 KIF1B MCM6 LRRK1 CIT KIAA1614 GSDMA C3 SPAG17 ATP2A2 PKN3

9.80e-0493713112EFO_0007988
Diseasetriacylglycerol 56:2 measurement

MACROD2 LIMCH1

1.05e-03111312EFO_0010429
DiseaseFEV/FEC ratio

U2SURP KIF1B TASP1 ITGAV INPP4B C17orf58 AGBL4 KIF3B DST CROCC2 RASGRP3 FTO MYO15A TNXB

1.14e-03122813114EFO_0004713
Diseaseoncostatin-M measurement

GSDMA C3

1.25e-03121312EFO_0010792
Diseaseamyotrophic lateral sclerosis (biomarker_via_orthology)

KIF1B C3

1.48e-03131312DOID:332 (biomarker_via_orthology)
DiseaseN-acetyltaurine measurement

PCDHA4 SLC6A2

1.48e-03131312EFO_0020023
DiseaseCongestive heart failure

ACLY ATP2A2 HSPB1 SOD1

1.49e-031101314C0018802
DiseaseHeart failure

ACLY ATP2A2 HSPB1 SOD1

1.49e-031101314C0018801
DiseaseLeft-Sided Heart Failure

ACLY ATP2A2 HSPB1 SOD1

1.49e-031101314C0023212
DiseaseHeart Failure, Right-Sided

ACLY ATP2A2 HSPB1 SOD1

1.49e-031101314C0235527
DiseaseHeart Decompensation

ACLY ATP2A2 HSPB1 SOD1

1.49e-031101314C1961112
DiseaseMyocardial Failure

ACLY ATP2A2 HSPB1 SOD1

1.49e-031101314C1959583
DiseaseAcute Cerebrovascular Accidents

ITGAV CASZ1 SOD1

1.80e-03541313C0751956
Diseaseurate measurement, bone density

CRACR2A SYNE1 CASZ1 SLC6A2 ASS1 FTO DNAH8 TNXB PDZD2

1.82e-036191319EFO_0003923, EFO_0004531
DiseaseBody Weight

HRC FTO

1.98e-03151312C0005910
Diseaseneurofilament light chain measurement

SLC6A2 MYO15A MTDH

2.10e-03571313EFO_0009178
Diseaseheart disease (biomarker_via_orthology)

CP ATP2A2

2.55e-03171312DOID:114 (biomarker_via_orthology)
Diseaseocular hypertension (biomarker_via_orthology)

C3 SOD1

2.55e-03171312DOID:9282 (biomarker_via_orthology)
Diseasesex interaction measurement, ulcerative colitis

GPSM1 TNXB

2.55e-03171312EFO_0000729, EFO_0008343
DiseaseCharcot-Marie-Tooth disease type 2

KIF1B HSPB1

2.55e-03171312cv:C0270914
DiseaseCerebrovascular accident

ITGAV CASZ1 SOD1

2.67e-03621313C0038454
Diseasecutaneous melanoma, hair color

RASA3 MED13L FTO

2.67e-03621313EFO_0000389, EFO_0003924
Diseaseessential hypertension (is_implicated_in)

FTO ATP2A2

2.86e-03181312DOID:10825 (is_implicated_in)
Diseaseneck circumference

INPP4B FTO

3.18e-03191312EFO_0011043
DiseaseIschemic stroke

MORN1 KBTBD8 CASZ1 SLC6A2 MACROD2 FUT8

3.32e-033241316HP_0002140
Diseasesporadic amyotrophic lateral sclerosis

INPP4B RBM19 MACROD2 HADHA

3.57e-031401314EFO_0001357
Diseasebipolar I disorder

SYNE1 PCDHA1 MACROD2 ATP2A2

3.66e-031411314EFO_0009963
Diseasechronic obstructive pulmonary disease

KIF1B TASP1 VWA7 KIF3B RASGRP3 CC2D2A FTO ATP2A2 PDZD2

3.68e-036881319EFO_0000341
Diseasecardiovascular system disease (is_implicated_in)

DDAH1 FTO

3.89e-03211312DOID:1287 (is_implicated_in)
Diseasesystemising measurement

NBAS FUT8

3.89e-03211312EFO_0010221
DiseaseIntellectual Disability

SYNE1 GRIN1 MED13L TRRAP CSDE1 ASS1 FUT8

3.90e-034471317C3714756
Diseasebody weight

COL16A1 KIZ PCDHA1 ZZEF1 AGBL4 NBAS RBM19 MACROD2 ZNF638 ADAMTS14 FTO EPB41L2 PDZD2

4.08e-03126113113EFO_0004338
Diseaseblood urea nitrogen measurement

KBTBD8 MCM6 KIAA1614 CASZ1 FTO FUT8 PCCB

4.15e-034521317EFO_0004741
DiseaseAutosomal Recessive Primary Microcephaly

NCAPD3 CIT

4.26e-03221312C3711387

Protein segments in the cluster

PeptideGeneStartEntry
RTVHAGEVGSAEVVK

ADA

211

P00813
FKVVRAGVHAPEEVG

CCDC115

81

Q96NT0
QVVVEKRADAGSHTE

CASZ1

41

Q86V15
AERGAKVHQETAADE

COL16A1

301

Q07092
TNDVGALKHADVGVA

ATP13A1

866

Q9HD20
FQEEGKEGENRAVIH

ARPC2

131

O15144
GDVHEGFRTLKEEVQ

GSDMA

251

Q96QA5
DVKRHVLQVHEGGGE

GZF1

391

Q9H116
EGDHGARVVLVAVDK

C3

586

P01024
HVKEVQDGIELQAGD

CSDE1

701

O75534
EDAGEQVAQRHEEKV

CRACR2A

126

Q9BSW2
EEEEKGGTHVNDVLN

RAD54L2

226

Q9Y4B4
GHFAEVQVVREKATG

CIT

106

O14578
KVTDGFTQGHIVEVV

IQCA1

736

Q86XH1
EVAGKHGVGRIDIVE

ASS1

256

P00966
ERGQQEKEASGRTHV

ADAMTS14

191

Q8WXS8
DHETKGSVAVRVALG

RBM19

541

Q9Y4C8
KQVIAGVGALEQEHA

RASA3

781

Q14644
KVEAENSEVRGHLGR

RIMBP3B

631

A6NNM3
KVEAENSEVRGHLGR

RIMBP3C

631

A6NJZ7
HGTVVEGRKIEVNNA

RBFOX2

181

O43251
GVIQELEKGEAHREG

INSYN2A

381

Q6ZSG2
EVRSGGTVVENGVHK

PALM2

181

Q8IXS6
GAGHVVAKVRAVDAD

PCDHA2

586

Q9Y5H9
GLTGQAEAREHAKET

YOD1

326

Q5VVQ6
EVGDTIRVTFHNKGA

CP

456

P00450
QDHGEIAKSESGRVL

MORN1

241

Q5T089
GAGHVVAKVRAVDAD

PCDHA7

586

Q9UN72
AGSQHLEVRDEVAEK

MCM6

11

Q14566
GAGHVVAKVRAVDAD

PCDHA8

586

Q9Y5H6
GAGHVVAKVRAVDAD

PCDHA3

586

Q9Y5H8
VHEANGTEDERAVSK

LIMS3

26

P0CW19
VHEANGTEDERAVSK

LIMS4

26

P0CW20
LSVNGVSVEGEQHEK

LIN7B

141

Q9HAP6
GEDEALARHTGNVVI

LFNG

151

Q8NES3
GGKVDEALVRSATVH

MED13L

1291

Q71F56
IEVEAENGDGVIKSH

IL31RA

96

Q8NI17
IHEDEVAKTQKAEGG

WWC1

501

Q8IX03
HGVLVDAAVVAKDTV

LRRK1

1956

Q38SD2
EQEELSKREVVAVGH

MYO15A

1986

Q9UKN7
RHLSIAQEQGDKVGE

GPSM1

131

Q86YR5
DGGKVDTSATHREVQ

DST

4001

Q03001
EGVTNAVLHEVKREG

FTO

411

Q9C0B1
HRVAIVSEKGEVRGF

KIF1B

991

O60333
EFAVNGIVHDVDVLG

C17orf58

211

Q2M2W7
DGEADHITTDVQGQK

INPP4B

191

O15327
HHGQEGSILVTKVEE

GMPPB

126

Q9Y5P6
DDVEVENEVKEGRGH

KIAA1614

681

Q5VZ46
KRIVITGDGDIDHDQ

EPB41L2

956

O43491
EVGAGHSVNEETKAE

EXOC3-AS1

26

Q8N2X6
RHQEGKVSDEREGTT

GPATCH4

246

Q5T3I0
NVVRKHISDGVADSG

RHOT1

231

Q8IXI2
IVVTQVKEGGAAHRD

PDZD2

361

O15018
QRKHVVFGSETGEGE

DNAH8

796

Q96JB1
TGVKITVVAGEHNIE

F9

271

P00740
GVVEITGKHEERQDE

HSPB1

116

P04792
KDNHVVAAGGVEKAV

QPRT

171

Q15274
ESEIHVVRGEGFKTV

LRRC63

286

Q05C16
GHVKDTNQEDGVIIS

PAXBP1

166

Q9Y5B6
EEAKHGTFVGRIAQD

PCDHA5

36

Q9Y5H7
EDREKVAVHEGINSG

KIZ

131

Q2M2Z5
HGEKERQVSEAEENG

NPIPA2

176

E9PIF3
EGVVAAVHASVDKGE

NBAS

2066

A2RRP1
EKLDVTGNGHEEVVA

ITFG2

311

Q969R8
GQLTDIVVEVDHGKT

KBTBD8

46

Q8NFY9
GAGHVVAKVRAVDAD

PCDHA1

586

Q9Y5I3
GAGHVVAKVRAVDAD

PCDHA13

586

Q9Y5I0
NEDVTQEELGGAKTH

PCCB

236

P05166
GVGHVVAKVRAVDAD

PCDHA4

586

Q9UN74
DGIAVDHVVGLNTEK

BOD1L1

1436

Q8NFC6
GRKDNAEAISGHSVE

BOD1L1

2741

Q8NFC6
TKTVEEVLGHFGVNE

ATP2A2

6

P16615
VENAHVAGKTTGEVV

CKAP5

76

Q14008
AKGTIHGEEVEQEKI

CD8B2

76

A6NJW9
VDKASVRHGGENVAA

ILVBL

46

A1L0T0
AVVIHKGSDESEGER

BSND

161

Q8WZ55
KARHRAGTNQEEEEG

CC2D2A

211

Q9P2K1
QRKLAEVEAAGEAHG

CROCC2

1206

H7BZ55
AKGTIHGEEVEQEKI

CD8B

76

P10966
TEKNDTVAGQGERDH

ITGAV

871

P06756
EVVKEVVGHAKETGE

FAM25E

116

A8MYX2
EGAEQKVVFITGRVH

AGBL4

216

Q5VU57
KSLQGVAGVQDVEVH

CCS

31

O14618
EVEKGEGRLQTTHEE

BICDL2

226

A1A5D9
VQNSSRHDGKEVDEG

MTDH

176

Q86UE4
KISVVGRRHETGVDD

DHDH

196

Q9UQ10
TLVDEVGVDVAKHVA

HADHA

586

P40939
QHEQRKEAGNIESGV

EFHB

226

Q8N7U6
SRAHAVEGQVEDVVG

LAMB3

971

Q13751
ENHIQRKEIFGTEGV

CFAP69

546

A5D8W1
HEGKQLVNGEVSDER

RSF1

436

Q96T23
QGAKEHEEAENITEG

SLC12A6

161

Q9UHW9
SGITHAGREVEKVFN

SBSN

56

Q6UWP8
QVGKEEDRVVQGLHH

SBSN

396

Q6UWP8
GQHALRSAKGEEVDV

DDAH1

26

O94760
VDGKVSVNGETVHRE

LIMCH1

556

Q9UPQ0
FVRVSGEATIGHVEK

PCGF6

276

Q9BYE7
GAGHVVAKVRAVDAD

PCDHA12

586

Q9UN75
RLHVEAAVAEGAKNV

PKN3

186

Q6P5Z2
TKGGEVTDHSVRDQD

MACROD2

311

A1Z1Q3
VEANEENVKVHGGRK

RPGR

811

Q92834
GVHVRRTDKVGTEAA

FUT8

361

Q9BYC5
ETGSREVVSHVIKQG

HPD

51

P32754
EHKVNIEDVATEGAG

SLC6A2

371

P23975
ENRIGNSGVEEIKGH

STK38L

366

Q9Y2H1
KGEAIDTANHGEVKR

SYNE1

1151

Q8NF91
DTANHGEVKRAVEEI

SYNE1

1156

Q8NF91
KEGAAVIDVGINRVH

MTHFD2

266

P13995
KVEAENSEVRGHLGR

RIMBP3

631

Q9UFD9
EKPRVHAGVDVVDRG

RASGRP3

656

Q8IV61
DIARHQIVEVAGDDK

ARHGAP1

66

Q07960
QDEETGHGQRGSIKE

HRC

446

P23327
KDEERHVGDLGNVTA

SOD1

76

P00441
VERKDGTRIVDHADG

SPAG17

1441

Q6Q759
VRGGVVNAAKEEHET

U2SURP

136

O15042
HEGGVDVGDVDAKAQ

ACLY

136

P53396
QKVRGVDVVVGGHSN

NT5E

231

P21589
IAEEHIQKVAIFGGT

ASPA

6

P45381
EQELAKHADVAGTAG

NCAPD3

1266

P42695
GINEAVAAVTEEEHK

CNDP2

261

Q96KP4
VGANQVTVRKGEKDH

C10orf90

376

Q96M02
EEKRVGTRTVFVGNH

ATP11C

16

Q8NB49
DASHKIEVEGVTRGA

XIRP2

786

A4UGR9
GSKIVSVGDDQEIHI

WDR61

286

Q9GZS3
QKEGVIGVTEEQVHH

SUN2

516

Q9UH99
SEVGLDGENHIRVGK

KIF3B

226

O15066
EHTVEGGEKQVVFTH

TNXB

61

P22105
QKVSSEQGRVEHLGD

TANGO6

566

Q9C0B7
SREVKEHVGTDQFGN

NDUFAF2

16

Q8N183
VENETHGKIKNVIGE

SERPINB7

146

O75635
QEEEEHGVKGVESVL

nan

46

Q3C1V9
KEEQIHSVDIGNDGS

XRCC1

51

P18887
SEAGNGKRAVHEEIR

ZZEF1

2001

O43149
AGQVARVVHITEDGQ

ZNF407

1896

Q9C0G0
GDTQVVVFKHEKEDG

CCT8

356

P50990
GGEVIFTKDQHIRDV

VWA7

476

Q9Y334
EVQVGKRSTEARHGV

PLD2

266

O14939
GAVVVDHEGNVAAAV

TASP1

236

Q9H6P5
EVVVITHKGGQRSDG

TRRAP

1476

Q9Y4A5
KGSHISQGNEAEERE

UIMC1

166

Q96RL1
KALEDVVQRSGHGTE

ZNF638

576

Q14966
AHEGDILQIKAVEGS

WDR81

1826

Q562E7
DSGKIVINVGGVRHE

KCNC3

86

Q14003
GNVVGIVAARAHEED

NAT8L

191

Q8N9F0
IFVKTVTEGGAAHRD

PPP1R9B

526

Q96SB3
VHLVADGKFGTQERV

GRIN1

476

Q05586