Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	supercoiled DNA binding	HMGB1 TOP1	9.53e-05	6	51	2	GO:0097100
GeneOntologyMolecularFunction	structural constituent of cytoskeleton	CYLC1 CYLC2 POTEJ MYBPC2	3.38e-04	130	51	4	GO:0005200
GeneOntologyCellularComponent	cytoskeletal calyx	CYLC1 CYLC2	1.75e-05	3	51	2	GO:0033150
GeneOntologyCellularComponent	perinuclear theca	CYLC1 CYLC2	5.81e-05	5	51	2	GO:0033011
Domain	Cylicin_N	CYLC1 CYLC2	6.74e-06	2	49	2	IPR029354
Domain	CYLC	CYLC1 CYLC2	6.74e-06	2	49	2	IPR026189
Domain	Cylicin_N	CYLC1 CYLC2	6.74e-06	2	49	2	PF15241
Domain	SH3_9	ASAP2 NEBL ARHGAP10 ARHGAP26	5.17e-05	78	49	4	PF14604
Domain	SH3_1	ASAP2 NEBL ARHGAP10 ARHGAP26 PACSIN2	6.85e-05	164	49	5	PF00018
Domain	SH3	ASAP2 NEBL ARHGAP10 ARHGAP26 PACSIN2	2.49e-04	216	49	5	SM00326
Domain	SH3	ASAP2 NEBL ARHGAP10 ARHGAP26 PACSIN2	2.49e-04	216	49	5	PS50002
Domain	SH3_domain	ASAP2 NEBL ARHGAP10 ARHGAP26 PACSIN2	2.71e-04	220	49	5	IPR001452
Domain	I-BAR_dom	ARHGAP10 ARHGAP26	5.16e-04	13	49	2	IPR013606
Domain	FCH	FER PACSIN2	1.51e-03	22	49	2	PF00611
Domain	FCH	FER PACSIN2	1.51e-03	22	49	2	SM00055
Domain	FCH_dom	FER PACSIN2	1.65e-03	23	49	2	IPR001060
Domain	F_BAR	FER PACSIN2	1.95e-03	25	49	2	IPR031160
Domain	F_BAR	FER PACSIN2	1.95e-03	25	49	2	PS51741
Domain	Ank_2	ASAP2 ANKRD11 ANKRD12 POTEJ	2.41e-03	215	49	4	PF12796
Domain	Ank	ASAP2 ANKRD11 ANKRD12 POTEJ	2.98e-03	228	49	4	PF00023
Domain	PH	ASAP2 ARHGAP10 ARHGAP26 PSD3	3.03e-03	229	49	4	PF00169
Domain	-	ASAP2 ANKRD11 ANKRD12 POTEJ	4.02e-03	248	49	4	1.25.40.20
Domain	ANK	ASAP2 ANKRD11 ANKRD12 POTEJ	4.20e-03	251	49	4	SM00248
Domain	ANK_REPEAT	ASAP2 ANKRD11 ANKRD12 POTEJ	4.32e-03	253	49	4	PS50088
Domain	Ankyrin_rpt-contain_dom	ASAP2 ANKRD11 ANKRD12 POTEJ	4.38e-03	254	49	4	IPR020683
Domain	ANK_REP_REGION	ASAP2 ANKRD11 ANKRD12 POTEJ	4.38e-03	254	49	4	PS50297
Domain	Ankyrin_rpt	ASAP2 ANKRD11 ANKRD12 POTEJ	4.89e-03	262	49	4	IPR002110
Domain	PH	ASAP2 ARHGAP10 ARHGAP26 PSD3	6.02e-03	278	49	4	SM00233
Domain	PH_DOMAIN	ASAP2 ARHGAP10 ARHGAP26 PSD3	6.09e-03	279	49	4	PS50003
Domain	PH_domain	ASAP2 ARHGAP10 ARHGAP26 PSD3	6.17e-03	280	49	4	IPR001849
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBM25 PAXBP1 ARID4B UBN1 RBBP6 ZMAT2 SLTM ANKRD11 HMGB1 CCDC50 TOP1 HMGB1P1 HSP90AA1 DDX10	8.34e-11	954	52	14	36373674
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	HMGN5 RBM25 PAXBP1 ARID4B UBN1 RBBP6 MACO1 SLTM ANKRD11 HMGB1 INO80 TOP1 RPRD1B	4.05e-08	1294	52	13	30804502
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	ARID4B ZMAT2 SEC62 HMGB1 TOP1 HSP90AA1	4.18e-07	191	52	6	20195357
Pubmed	Human transcription factor protein interaction networks.	TRAF3 RBM25 ARID4B UBN1 RBBP6 ZFP91 HMGB1 INO80 TOP1 CNOT3 PACSIN2 DDX10	9.92e-07	1429	52	12	35140242
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CYLC1 CYLC2 FAM114A1 ZMAT2 SEC62 HMGB1 CCDC50 POTEJ TOP1 HSP90AA1 CFAP46 MYBPC2	1.09e-06	1442	52	12	35575683
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RBM25 PAXBP1 ARID4B UBN1 RBBP6 ZFP91 USP16 CNOT3 RPRD1B	2.00e-06	774	52	9	15302935
Pubmed	The Association Between HSP90/topoisomerase I Immunophenotype and the Clinical Features of Colorectal Cancers in Respect to KRAS Gene Status.	TOP1 HSP90AA1	2.19e-06	2	52	2	28870917
Pubmed	Cylicins are a structural component of the sperm calyx being indispensable for male fertility in mice and human.	CYLC1 CYLC2	2.19e-06	2	52	2	38013430
Pubmed	High Mobility Group Box-1 Protein and Interleukin 33 Expression in Allergic Rhinitis.	HMGB1 IL33	2.19e-06	2	52	2	34979505
Pubmed	IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology.	HMGB1 IL33	2.19e-06	2	52	2	22530772
Pubmed	Cloning and analysis of a human 86-kDa heat-shock-protein-encoding gene.	HSP90AA1 HSP90AA2P	2.19e-06	2	52	2	2591742
Pubmed	HMGB1 regulates IL-33 expression in acute respiratory distress syndrome.	HMGB1 IL33	2.19e-06	2	52	2	27318792
Pubmed	The protein complexity of the cytoskeleton of bovine and human sperm heads: the identification and characterization of cylicin II.	CYLC1 CYLC2	2.19e-06	2	52	2	7737358
Pubmed	The "Alarmins" HMBG1 and IL-33 Downregulate Structural Skin Barrier Proteins and Impair Epidermal Growth.	HMGB1 IL33	2.19e-06	2	52	2	27868148
Pubmed	Differential expression of IL-33 and HMGB1 in the lungs of stable cystic fibrosis patients.	HMGB1 IL33	2.19e-06	2	52	2	24969657
Pubmed	IL-33 and HMGB1 modulate the progression of EAE via oppositely regulating each other.	HMGB1 IL33	2.19e-06	2	52	2	37467690
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	RBM25 UBN1 RBBP6 ZFP91 SLTM HMGB1 INO80 TOP1 HSP90AA1 RPRD1B	2.21e-06	1014	52	10	32416067
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	UBN1 RBBP6 MACO1 ZMAT2 AASDH CGNL1 POTEJ CNOT3	2.49e-06	588	52	8	38580884
Pubmed	The regulatory mechanism of extracellular Hsp90{alpha} on matrix metalloproteinase-2 processing and tumor angiogenesis.	HSP90AA1 HSP90AA2P	6.57e-06	3	52	2	20937816
Pubmed	Downregulation of HMGB1 carried by macrophage-derived extracellular vesicles delays atherosclerotic plaque formation through Caspase-11-dependent macrophage pyroptosis.	CASP5 HMGB1	6.57e-06	3	52	2	38493291
Pubmed	Targeting the P2Y13 Receptor Suppresses IL-33 and HMGB1 Release and Ameliorates Experimental Asthma.	HMGB1 IL33	6.57e-06	3	52	2	34860143
Pubmed	Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness.	HSP90AA1 HSP90AA2P	6.57e-06	3	52	2	15146192
Pubmed	Tumor suppressor lnc-CTSLP4 inhibits EMT and metastasis of gastric cancer by attenuating HNRNPAB-dependent Snail transcription.	ZFP91 HSP90AA1	6.57e-06	3	52	2	33717650
Pubmed	The Role of Alarmins in Osteoarthritis Pathogenesis: HMGB1, S100B and IL-33.	HMGB1 IL33	6.57e-06	3	52	2	37569519
Pubmed	A human MAP kinase interactome.	ASAP2 ARID4B RBBP6 LAMB1 CGNL1 PACSIN2 HSP90AA1	7.74e-06	486	52	7	20936779
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	HMGN5 ASAP2 RBM25 ARHGAP10 MACO1 ARHGAP26 HMGB1 CCDC50 PACSIN2	7.81e-06	916	52	9	32203420
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	NEBL RBBP6 ZMAT2 CCDC50 CGNL1 USP16 TOP1 HSP90AA1 DDX10	9.13e-06	934	52	9	33916271
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	RBM25 PAXBP1 RBBP6 ZMAT2 HMGB1 POTEJ DDX10	1.01e-05	506	52	7	30890647
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PAXBP1 NEBL RBBP6 ARHGAP10 MACO1 ZFP91 ANKRD11 CCDC50 INO80 CNOT3 DDX10	1.07e-05	1497	52	11	31527615
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	ZMAT2 ZFP91 FER INO80 USP16 TOP1 LACTB DDX10	1.14e-05	724	52	8	36232890
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	RBM25 PAXBP1 RBBP6 ZMAT2 SLTM TOP1 HSP90AA1 DDX10	1.22e-05	731	52	8	29298432
Pubmed	The levels of retinoic acid-inducible gene I are regulated by heat shock protein 90-alpha.	HSP90AA1 HSP90AA2P	1.31e-05	4	52	2	19234166
Pubmed	Mapping of the gene family for human heat-shock protein 90 alpha to chromosomes 1, 4, 11, and 14.	HSP90AA1 HSP90AA2P	1.31e-05	4	52	2	1740332
Pubmed	Heat shock protein 90 (Hsp90) selectively regulates the stability of KDM4B/JMJD2B histone demethylase.	HSP90AA1 HSP90AA2P	1.31e-05	4	52	2	23589305
Pubmed	Unconventional Pathways of Secretion Contribute to Inflammation.	HMGB1 IL33	1.31e-05	4	52	2	28067797
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	OTOF RBBP6 MACO1 ZFP91 SLTM TOP1	1.63e-05	361	52	6	26167880
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TRAF3 RBBP6 SEC62 SLTM LAMB1 HMGB1 TOP1 CNOT3 HSP90AA1 RPRD1B	1.91e-05	1297	52	10	33545068
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	HMGN5 RBM25 RBBP6 SLTM HMGB1 TOP1 HSP90AA1 DDX10	2.48e-05	807	52	8	22681889
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	HMGN5 ARID4B UBN1 ZFP91 INO80 TOP1 DDX10	3.26e-05	608	52	7	36089195
Pubmed	Standardized tape stripping prior to patch testing induces upregulation of Hsp90, Hsp70, IL-33, TNF-α and IL-8/CXCL8 mRNA: new insights into the involvement of 'alarmins'.	IL33 HSP90AA1	3.28e-05	6	52	2	20731692
Pubmed	PKNbeta interacts with the SH3 domains of Graf and a novel Graf related protein, Graf2, which are GTPase activating proteins for Rho family.	ARHGAP10 ARHGAP26	3.28e-05	6	52	2	11432776
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	RBM25 PAXBP1 RBBP6 ZFP91 SLTM INO80 TOP1 HSP90AA1	3.49e-05	847	52	8	35850772
Pubmed	Interactome of Aiolos/Ikaros Reveals Combination Rationale of Cereblon Modulators with HDAC Inhibitors in DLBCL.	RBM25 HMGB1 TOP1 HSP90AA1	3.54e-05	123	52	4	35583604
Pubmed	USP13 regulates HMGB1 stability and secretion through its deubiquitinase activity.	HMGB1 HSP90AA1	4.58e-05	7	52	2	36585612
Pubmed	The functional interactome landscape of the human histone deacetylase family.	PAXBP1 ARID4B ANKRD11 ANKRD12 TOP1	7.23e-05	289	52	5	23752268
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	ARID4B FER PSD3 HMGB1 INO80 TOP1	7.52e-05	475	52	6	31040226
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	RBM25 RBBP6 ZFP91 SLTM TOP1 HSP90AA1 HSP90AA2P DDX10	7.75e-05	949	52	8	36574265
Pubmed	Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation.	HMGB1 IL33	7.84e-05	9	52	2	24257755
Pubmed	GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508.	ARHGAP10 ARHGAP26	7.84e-05	9	52	2	32344433
Pubmed	Identification of a novel family of ankyrin repeats containing cofactors for p160 nuclear receptor coactivators.	ANKRD11 ANKRD12	7.84e-05	9	52	2	15184363
Pubmed	The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.	CASP5 HMGB1	7.84e-05	9	52	2	30314759
Pubmed	The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA.	RBBP6 TOP1	7.84e-05	9	52	2	33524014
Pubmed	Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.	UBN1 USP16 TOP1	8.26e-05	56	52	3	26919559
Pubmed	Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.	SEC62 LACTB HSP90AA1	8.71e-05	57	52	3	17208939
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	RBM25 PAXBP1 NEBL RBBP6 LAMB1 HMGB1 TOP1 CNOT3 HSP90AA1	8.72e-05	1247	52	9	27684187
Pubmed	An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.	TRAF3 HSP90AA1	9.79e-05	10	52	2	24120361
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	HMGN5 RBM25 PAXBP1 RBBP6 HMGB1 USP16 TOP1 HSP90AA1 DDX10	1.33e-04	1318	52	9	30463901
Pubmed	An integrated genetic, radiation hybrid, physical and transcription map of a region of distal mouse chromosome 12, including an imprinted locus and the 'Legs at odd angles' (Loa) mutation.	TRAF3 HSP90AA1	1.43e-04	12	52	2	11867214
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	SLTM LAMB1 TOP1 HSP90AA1 RPRD1B HSP90AA2P	1.48e-04	538	52	6	28524877
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	RBM25 SLTM TOP1 LACTB RPRD1B	1.55e-04	340	52	5	29478914
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	RBM25 RBBP6 FER USP16 TOP1 HSP90AA1	1.62e-04	547	52	6	37267103
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	TCEA3 RBM25 PAXBP1 SEC62 ZFP91 POTEJ TOP1 LACTB DDX10	1.78e-04	1371	52	9	36244648
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RBM25 PAXBP1 RBBP6 SLTM HMGB1 INO80 TOP1 HSP90AA1	1.91e-04	1082	52	8	38697112
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	PAXBP1 ARHGAP26 SLTM CCDC50 ANKRD12 INO80 PACSIN2 RPRD1B	1.93e-04	1084	52	8	11544199
Pubmed	PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78.	HSP90AA1 HSP90AA2P	1.97e-04	14	52	2	29178343
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	RBM25 ARID4B RBBP6 ARHGAP10 ZFP91 LAMB1 INO80 TOP1	2.36e-04	1116	52	8	31753913
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TRAF3 CLGN UBN1 MACO1 SEC62 LAMB1 HMGB1 CNOT3 HSP90AA1	2.57e-04	1440	52	9	30833792
Pubmed	Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer.	RBM25 RBBP6 TOP1 HSP90AA1	2.59e-04	206	52	4	34185411
Pubmed	The HSP90 family of genes in the human genome: insights into their divergence and evolution.	HSP90AA1 HSP90AA2P	2.60e-04	16	52	2	16269234
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PAXBP1 MACO1 PSD3 ANKRD11 LAMB1 USP16 PACSIN2 LACTB DDX10	3.25e-04	1487	52	9	33957083
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	SLTM USP16 LACTB	3.60e-04	92	52	3	15840729
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	RBM25 RBBP6 SEC62 ZFP91 SLTM HMGB1	4.19e-04	653	52	6	33742100
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	PAXBP1 ARID4B RBBP6 ANKRD11 HMGB1 LACTB HSP90AA1	4.26e-04	922	52	7	27609421
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	ASAP2 CCDC50 HSP90AA1 HSP90AA2P	4.26e-04	235	52	4	30258100
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	RBBP6 HMGB1 CCDC50 PACSIN2 RPRD1B	4.31e-04	425	52	5	24999758
Pubmed	Identification of novel ARF binding proteins by two-hybrid screening.	ZFP91 ANKRD12	4.52e-04	21	52	2	16582619
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	RBM25 PAXBP1 RBBP6 TOP1 CNOT3 HSP90AA1	5.10e-04	678	52	6	30209976
Pubmed	The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.	RBM25 PAXBP1 TOP1	5.16e-04	104	52	3	31365120
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	RBM25 RBBP6 SLTM HMGB1 USP16 TOP1 LACTB HSP90AA1	5.21e-04	1257	52	8	36526897
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	PAXBP1 RBBP6 ARHGAP10 TOP1	5.46e-04	251	52	4	31076518
Pubmed	The protein interaction landscape of the human CMGC kinase group.	RBM25 RBBP6 ARHGAP26 HMGB1 TOP1 CNOT3	5.81e-04	695	52	6	23602568
Pubmed	Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination.	TRAF3 CASP5	5.93e-04	24	52	2	27709293
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	PAXBP1 RBBP6 ZMAT2 SLTM USP16	6.73e-04	469	52	5	27634302
Pubmed	Insights into the ubiquitin-proteasome system of human embryonic stem cells.	RBM25 PAXBP1 ANKRD11 TOP1	7.08e-04	269	52	4	29511261
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	ARHGAP26 PSD3 ANKRD11 HSP90AA1	7.38e-04	272	52	4	31010829
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	RBBP6 TOP1 HSP90AA1 DDX10	7.58e-04	274	52	4	34244482
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	RBBP6 ARHGAP10 SLTM LAMB1 POTEJ	8.65e-04	496	52	5	31343991
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	ASAP2 ARID4B LAMB1 HSP90AA1	8.66e-04	284	52	4	29459677
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	HMGN5 ARHGAP10 MACO1 PSD3 SLTM HMGB1 HSP90AA1	9.12e-04	1049	52	7	27880917
Pubmed	Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs.	ZFP91 ANKRD11	9.29e-04	30	52	2	11483580
Pubmed	TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation.	TRAF3 HSP90AA2P	9.92e-04	31	52	2	25996949
Pubmed	Genome-wide association study of periodontal pathogen colonization.	OTOF IL33	9.92e-04	31	52	2	22699663
Pubmed	Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control.	HMGB1 HSP90AA1	9.92e-04	31	52	2	25817432
Pubmed	E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.	LAMB1 HSP90AA1 DDX10	1.10e-03	135	52	3	29859926
Pubmed	Landscape of the SOX2 protein-protein interactome.	SLTM LACTB HSP90AA1	1.12e-03	136	52	3	21280222
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TRAF3 RBM25 ZFP91 ANKRD11 PACSIN2	1.22e-03	536	52	5	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TRAF3 RBM25 ZFP91 ANKRD11 PACSIN2	1.24e-03	538	52	5	10512203
Pubmed	DEPDC1B coordinates de-adhesion events and cell-cycle progression at mitosis.	LACTB HSP90AA1	1.26e-03	35	52	2	25458010
Pubmed	ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas.	CYLC2 SEC62 RPRD1B	1.27e-03	142	52	3	30232004
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	RBM25 TOP1 HSP90AA1 DDX10	1.28e-03	316	52	4	31665637
Interaction	SMC5 interactions	RBM25 PAXBP1 ARID4B UBN1 RBBP6 ZMAT2 SLTM ANKRD11 HMGB1 CCDC50 TOP1 HMGB1P1 HSP90AA1 DDX10	1.51e-07	1000	52	14	int:SMC5
Interaction	TERF2IP interactions	PAXBP1 RBBP6 ZMAT2 ANKRD11 HMGB1 TOP1 PACSIN2 RPRD1B DDX10	1.05e-05	552	52	9	int:TERF2IP
Interaction	RALBP1 interactions	RBM25 ARHGAP26 HMGB1 TOP1 HMGB1P1 HSP90AA1	1.17e-05	198	52	6	int:RALBP1
Interaction	H2BC12 interactions	CYLC1 HMGN5 SLTM ANKRD11 USP16 CNOT3 RPRD1B	1.80e-05	322	52	7	int:H2BC12
Interaction	TERF2 interactions	CYLC2 PAXBP1 SLTM HMGB1 TOP1 HSP90AA1 RPRD1B	2.55e-05	340	52	7	int:TERF2
Interaction	DDX23 interactions	RBM25 PAXBP1 RBBP6 SLTM ANKRD11 HMGB1 TOP1 DDX10	2.93e-05	480	52	8	int:DDX23
Interaction	TRIM37 interactions	TRAF3 RBM25 UBN1 RBBP6 ZMAT2 ANKRD11 ANKRD12 POTEJ HSP90AA1	2.98e-05	630	52	9	int:TRIM37
Interaction	POLR1G interactions	ARID4B ZMAT2 ZFP91 ANKRD11 HMGB1 TOP1 RPRD1B DDX10	3.34e-05	489	52	8	int:POLR1G
Interaction	DHX40 interactions	ASAP2 PAXBP1 RBBP6 SLTM ANKRD11 DDX10	4.24e-05	249	52	6	int:DHX40
Interaction	ZBTB49 interactions	TRAF3 HSP90AA1 CFAP46	5.65e-05	29	52	3	int:ZBTB49
Interaction	SSRP1 interactions	RBBP6 ZMAT2 ZFP91 SLTM ANKRD11 LAMB1 HMGB1 TOP1 RPRD1B	5.71e-05	685	52	9	int:SSRP1
Interaction	H2BC21 interactions	CYLC1 ARID4B OTOF FER LAMB1 TOP1 IL33 CFAP46 RPRD1B	6.46e-05	696	52	9	int:H2BC21
Interaction	H3C1 interactions	CYLC2 HMGN5 ARID4B UBN1 ARHGAP10 ZMAT2 ZFP91 HMGB1 TOP1 DDX10	8.69e-05	901	52	10	int:H3C1
Interaction	IKZF1 interactions	RBM25 ZMAT2 ANKRD11 HMGB1 TOP1 HSP90AA1	9.48e-05	288	52	6	int:IKZF1
Interaction	ACTL6A interactions	ARID4B ARHGAP26 INO80 TOP1 CNOT3 RPRD1B	9.66e-05	289	52	6	int:ACTL6A
Interaction	POLR2E interactions	HMGN5 LAMB1 TOP1 HSP90AA1 FKBP14 RPRD1B	1.37e-04	308	52	6	int:POLR2E
Interaction	ZNF330 interactions	ARID4B ZMAT2 ZFP91 ANKRD11 HMGB1 TOP1 DDX10	1.40e-04	446	52	7	int:ZNF330
Interaction	PLG interactions	RBBP6 ARHGAP26 HMGB1 HSP90AA1	1.61e-04	106	52	4	int:PLG
Interaction	NAA40 interactions	HMGN5 NEBL RBBP6 ZMAT2 CCDC50 CGNL1 USP16 TOP1 HSP90AA1 DDX10	1.70e-04	978	52	10	int:NAA40
Interaction	EP300 interactions	NUTM1 RBM25 UBN1 RBBP6 SEC62 ZFP91 SLTM HMGB1 CNOT3 HMGB1P1 RPRD1B HSP90AA2P	1.85e-04	1401	52	12	int:EP300
Interaction	SNRPA interactions	RBM25 PAXBP1 RBBP6 ZMAT2 SLTM TOP1 RPRD1B	2.26e-04	482	52	7	int:SNRPA
Interaction	TNIP1 interactions	HMGN5 TRAF3 RBM25 RBBP6 ZMAT2 ZFP91 SLTM TOP1 HSP90AA1 HSP90AA2P DDX10	2.27e-04	1217	52	11	int:TNIP1
Interaction	TAX1BP1 interactions	TRAF3 SEC62 SLTM HMGB1 TOP1 CNOT3	2.41e-04	342	52	6	int:TAX1BP1
Cytoband	15q22.1	SLTM LACTB	2.63e-05	7	52	2	15q22.1
GeneFamily	Canonical high mobility group	HMGN5 HMGB1	2.10e-04	11	36	2	511
GeneFamily	Rho GTPase activating proteins\|F-BAR domain containing	FER PACSIN2	9.50e-04	23	36	2	1288
GeneFamily	Ankyrin repeat domain containing	ASAP2 ANKRD11 ANKRD12 POTEJ	1.32e-03	242	36	4	403
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP10 ARHGAP26	4.45e-03	50	36	2	721
Coexpression	LAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM	TCEA3 RBM25 UBN1 ARHGAP10 ARHGAP26 ANKRD11 HMGB1 CFAP46	1.57e-06	417	52	8	M39224
Coexpression	AIZARANI_LIVER_C20_LSECS_3	RBM25 RBBP6 ARHGAP26 ANKRD11 CCDC50 TOP1 IL33	1.85e-06	295	52	7	M39121
Coexpression	GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP	TRAF3 RBBP6 HMGB1 TOP1	1.02e-05	68	52	4	M1373
Coexpression	GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP	TRAF3 RBBP6 HMGB1 TOP1	1.28e-05	72	52	4	MM1131
Coexpression	BASAKI_YBX1_TARGETS_DN	PAXBP1 NEBL SEC62 PSD3 LAMB1 CCDC50 CGNL1	1.31e-05	398	52	7	M14877
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	PSD3 ANKRD11 ANKRD12 TOP1 HSP90AA1	2.67e-05	177	52	5	M39245
Coexpression	BUSSLINGER_GASTRIC_ISTHMUS_CELLS	ASAP2 RBM25 PSD3 SLTM HMGB1 TOP1 HSP90AA1	3.22e-05	458	52	7	M40010
Coexpression	MENON_FETAL_KIDNEY_4_PODOCYTES	NEBL SEC62 ANKRD11 ANKRD12 CGNL1	5.50e-05	206	52	5	M39254
Coexpression	SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP	RBM25 SLCO1A2 CCDC50 USP16 TOP1 HSP90AA1	1.45e-04	404	52	6	M19488
Coexpression	MARTIN_VIRAL_GPCR_SIGNALING_DN	UBN1 NEBL SLCO1A2	1.52e-04	52	52	3	M1330
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	HMGN5 RBM25 ARID4B ARHGAP26 SLTM CCDC50 TOP1	6.82e-06	298	51	7	Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	HMGN5 RBM25 SLCO1A2 ZMAT2 SLTM ANKRD11 HMGB1 TOP1	1.48e-05	469	51	8	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000	HMGN5 TCEA3 RBM25 ARID4B SLCO1A2 ARHGAP26 SLTM CCDC50 CGNL1 TOP1 IL33	1.65e-05	979	51	11	Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_1000	RBBP6 SLCO1A2 SEC62 ZFP91 FER CGNL1 IL33 FKBP14 RPRD1B	1.28e-04	819	51	9	gudmap_developingKidney_e15.5_Peripheral blastema_1000
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM25 ARID4B SLTM ANKRD11 HMGB1 ANKRD12 TOP1	1.90e-09	187	51	7	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	RBM25 RBBP6 ANKRD11 HMGB1 ANKRD12 USP16 HSP90AA1	2.93e-09	199	51	7	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	RBM25 ARID4B RBBP6 ANKRD11 ANKRD12 TOP1 HSP90AA1	3.03e-09	200	51	7	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM25 ARID4B SEC62 SLTM ANKRD11 TOP1	7.57e-08	188	51	6	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARID4B UBN1 ANKRD11 ANKRD12 TOP1 FKBP14	9.11e-08	194	51	6	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	RBM25 ARID4B OTOF ANKRD11 ANKRD12 USP16	9.98e-08	197	51	6	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	HMGN5 RBM25 RBBP6 SLTM ANKRD12 HSP90AA1	9.98e-08	197	51	6	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	RBM25 RBBP6 SLTM ANKRD11 ANKRD12 USP16	1.03e-07	198	51	6	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	RBM25 ARID4B OTOF ANKRD11 ANKRD12 USP16	1.03e-07	198	51	6	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RBM25 ARID4B OTOF ANKRD11 ANKRD12 USP16	1.03e-07	198	51	6	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	ARID4B RBBP6 ANKRD11 ANKRD12 USP16 HSP90AA1	1.06e-07	199	51	6	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	RBM25 ARID4B ANKRD11 ANKRD12 USP16 HSP90AA1	1.06e-07	199	51	6	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RBM25 ARID4B ARHGAP26 ANKRD11 ANKRD12	2.43e-06	188	51	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	RBM25 ANKRD11 ANKRD12 USP16 HSP90AA1	3.21e-06	199	51	5	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	ANKRD11 HMGB1 ANKRD12 USP16 HSP90AA1	3.21e-06	199	51	5	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	ARID4B RBBP6 ANKRD11 ANKRD12 USP16	3.21e-06	199	51	5	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RBM25 PAXBP1 ARID4B ANKRD11 ANKRD12	3.28e-06	200	51	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	ARID4B RBBP6 ANKRD11 ANKRD12	1.89e-05	138	51	4	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL ARHGAP10 SLCO1A2 ARHGAP26	4.90e-05	176	51	4	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL ARHGAP10 SLCO1A2 HSP90AA1	5.46e-05	181	51	4	071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCell	PBMC-Mild-cDC_9\|Mild / Compartment, Disease Groups and Clusters	CLGN ZFP91 PSD3 HSP90AA1	5.82e-05	184	51	4	2e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGN5 PAXBP1 ANKRD11 HSP90AA1	6.07e-05	186	51	4	4ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGN5 PAXBP1 ANKRD11 HSP90AA1	6.07e-05	186	51	4	15ab6666748a641226e42e6ca6eeaf186a501c95
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	RBM25 SLTM ANKRD11 ANKRD12	6.87e-05	192	51	4	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RBM25 ARID4B ARHGAP26 ANKRD12	6.87e-05	192	51	4	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	COVID-19_Mild-PLT_4\|World / Disease Group and Platelet Clusters	ARID4B MACO1 ANKRD12 TOP1	7.01e-05	193	51	4	98a52523aa1efd5d14a2878ed106828a80a33aa2
ToppCell	PND01\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HMGN5 NEBL ZFP91 ANKRD11	7.01e-05	193	51	4	c291345c11cfcbceacbdc001a5851f67478a2779
ToppCell	droplet-Limb_Muscle-MUSCLE-1m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBN1 RBBP6 TOP1 FKBP14	7.29e-05	195	51	4	fee9d13f48149cd5f921cfe4b8b3053cf6a6dbd2
ToppCell	COVID-19_Severe-PLT_4\|World / Disease Group and Platelet Clusters	ARID4B MACO1 SEC62 TOP1	7.44e-05	196	51	4	ad43efdd4d73b6615f65f06a315b33576e317473
ToppCell	NS-moderate-d_07-13-Epithelial-Secretory\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TCEA3 FAM114A1 NEBL IL33	7.44e-05	196	51	4	47930de6b47b7bf22d8dae8b7419a9cd1d22f0ea
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RBM25 ARID4B ANKRD11 ANKRD12	7.58e-05	197	51	4	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	COVID-19_Mild-PLT_4\|COVID-19_Mild / Disease Group and Platelet Clusters	ARID4B MACO1 ANKRD12 TOP1	7.73e-05	198	51	4	3d8c33dba759df0974aeb2b9a6b5167ae7a18e1f
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	ANKRD11 ANKRD12 USP16 HSP90AA1	7.89e-05	199	51	4	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	COVID-19-COVID-19_Mild\|COVID-19 / Disease, condition lineage and cell class	RBM25 ARID4B ANKRD11 ANKRD12	8.04e-05	200	51	4	62c25042086f1afd1102e0720e933c2e476468fd
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TCEA3 FAM114A1 PSD3 FKBP14	8.04e-05	200	51	4	ed093626a9cac7531a2bf02f6e345c5e84b8c060
Drug	2qfo	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID000600769
Drug	3-amino-5-chlorobenzoic acid	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID010986726
Drug	3eko	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID011160307
Drug	monocillin III	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID006478910
Drug	pochonin A	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID006478909
Drug	1uyi	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID005289232
Drug	PU-H71	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID009549213
Drug	NSC683666	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID005469153
Drug	H 64	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID006914564
Drug	SureCN4151355	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID015942101
Drug	1uyc	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID000448969
Drug	PU-9	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID000448971
Drug	P u 0	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID000448974
Drug	2qf6	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID013373715
Drug	CHEBI:42139	HSP90AA1 HSP90AA2P	5.12e-06	2	52	2	CID011562562
Drug	wedelolactone	CASP5 HSP90AA1 HSP90AA2P	1.25e-05	20	52	3	CID005281813
Drug	pochonin D	HSP90AA1 HSP90AA2P	1.53e-05	3	52	2	CID006478913
Drug	azaquinone	HSP90AA1 HSP90AA2P	1.53e-05	3	52	2	CID000099132
Drug	d 1 v	HSP90AA1 HSP90AA2P	1.53e-05	3	52	2	CID000683940
Drug	HM-9	HSP90AA1 HSP90AA2P	1.53e-05	3	52	2	CID000433437
Drug	Glyoxylspermidine	HSP90AA1 HSP90AA2P	1.53e-05	3	52	2	CID000133564
Drug	AC1MD0RC	HSP90AA1 HSP90AA2P	1.53e-05	3	52	2	CID002829073
Drug	uranyl chloride	HSP90AA1 HSP90AA2P	3.06e-05	4	52	2	CID000082259
Drug	methoxyhydroquinone	HSP90AA1 HSP90AA2P	3.06e-05	4	52	2	CID000069988
Drug	11p110	HSP90AA1 HSP90AA2P	3.06e-05	4	52	2	CID002382787
Drug	1uy7	HSP90AA1 HSP90AA2P	5.09e-05	5	52	2	CID005289227
Drug	1uyd	HSP90AA1 HSP90AA2P	5.09e-05	5	52	2	CID000448970
Drug	Org 31806	HSP90AA1 HSP90AA2P	5.09e-05	5	52	2	CID000164147
Drug	CRT0044876	HSP90AA1 HSP90AA2P	5.09e-05	5	52	2	CID000081409
Drug	HCV-796	HSP90AA1 HSP90AA2P	5.09e-05	5	52	2	CID011561383
Drug	chaetochromin	HSP90AA1 HSP90AA2P	5.09e-05	5	52	2	CID000053277
Drug	1,1-diphenyl-2-propyn-1-ol	HSP90AA1 HSP90AA2P	5.09e-05	5	52	2	CID000092976
Drug	Pinacidil [85371-64-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A	CYLC1 CLGN ARHGAP10 FER LAMB1	7.44e-05	191	52	5	5456_DN
Drug	Hantzsch ester	HSP90AA1 HSP90AA2P	7.63e-05	6	52	2	CID000070849
Drug	3-aminocoumarin	HSP90AA1 HSP90AA2P	7.63e-05	6	52	2	CID000074217
Drug	Pu x	HSP90AA1 HSP90AA2P	7.63e-05	6	52	2	CID000448976
Drug	chromomycin A3	TOP1 PACSIN2 HSP90AA1 HSP90AA2P	9.05e-05	103	52	4	CID000656673
Drug	17-aminogeldanamycin	HSP90AA1 HSP90AA2P	1.07e-04	7	52	2	CID000429444
Drug	Nepl	HSP90AA1 HSP90AA2P	1.07e-04	7	52	2	CID006439214
Drug	NSC330499	HSP90AA1 HSP90AA2P	1.07e-04	7	52	2	CID000433447
Drug	1,2,4,7,8-pentachlorodibenzo-p-dioxin	HSP90AA1 HSP90AA2P	1.07e-04	7	52	2	CID000042836
Drug	Zlll-mca	HSP90AA1 HSP90AA2P	1.07e-04	7	52	2	CID000132936
Drug	dienochlor	HSP90AA1 HSP90AA2P	1.07e-04	7	52	2	CID000016686
Drug	phenyldichloroarsine	HSP90AA1 HSP90AA2P	1.42e-04	8	52	2	CID000012762
Drug	GGMP	HSP90AA1 HSP90AA2P	1.42e-04	8	52	2	CID006443839
Drug	D-box	HSP90AA1 HSP90AA2P	1.42e-04	8	52	2	CID000133881
Drug	9-phenanthrol	HSP90AA1 HSP90AA2P	1.42e-04	8	52	2	CID000010229
Drug	5,8-quinolinedione	HSP90AA1 HSP90AA2P	1.82e-04	9	52	2	CID000388306
Drug	antheridiol	HSP90AA1 HSP90AA2P	1.82e-04	9	52	2	CID000159927
Drug	JJ3	HSP90AA1 HSP90AA2P	1.82e-04	9	52	2	CID009927355
Drug	boceprevir	HSP90AA1 HSP90AA2P	1.82e-04	9	52	2	CID010324367
Drug	nibentan	HSP90AA1 HSP90AA2P	1.82e-04	9	52	2	CID000177905
Drug	noviose	HSP90AA1 HSP90AA2P	1.82e-04	9	52	2	CID005461025
Drug	AC1NUZLU	CASP5 HMGB1 TOP1 HSP90AA1 HSP90AA2P	1.93e-04	234	52	5	CID005497170
Drug	ORG 2058	HMGB1 HSP90AA1 HSP90AA2P	2.17e-04	51	52	3	CID000119086
Drug	n-C6	HSP90AA1 HSP90AA2P	2.28e-04	10	52	2	CID006420120
Drug	PU-6	HSP90AA1 HSP90AA2P	2.28e-04	10	52	2	CID000448968
Drug	formetanate	HSP90AA1 HSP90AA2P	2.28e-04	10	52	2	CID000031099
Drug	AC1L44ZM	HSP90AA1 HSP90AA2P	2.28e-04	10	52	2	CID000200744
Drug	PCI 5002	RBM25 ARID4B RBBP6 ANKRD11 ANKRD12 TOP1 HSP90AA1 DDX10	2.43e-04	735	52	8	ctd:C568608
Drug	AC1L4LMA	ZFP91 HSP90AA1 HSP90AA2P	2.57e-04	54	52	3	CID000208924
Drug	Pu-3	HSP90AA1 HSP90AA2P	2.78e-04	11	52	2	CID000448965
Drug	AC1L9ICX	HSP90AA1 HSP90AA2P	2.78e-04	11	52	2	CID000445664
Drug	I-hu	HSP90AA1 HSP90AA2P	2.78e-04	11	52	2	CID009547901
Drug	VER-49009	HSP90AA1 HSP90AA2P	2.78e-04	11	52	2	CID005327095
Drug	2ohu	HSP90AA1 HSP90AA2P	3.33e-04	12	52	2	CID011633167
Drug	4-oxo-2-nonenal	HSP90AA1 HSP90AA2P	3.33e-04	12	52	2	CID006445537
Drug	AHBA	HSP90AA1 HSP90AA2P	3.93e-04	13	52	2	CID000127115
Drug	AC1L85F0	HSP90AA1 HSP90AA2P	3.93e-04	13	52	2	CID000372766
Drug	steroid D	HSP90AA1 HSP90AA2P	3.93e-04	13	52	2	CID000454475
Drug	CMV423	HSP90AA1 HSP90AA2P	3.93e-04	13	52	2	CID000489128
Drug	TNP-GTP	HSP90AA1 HSP90AA2P	3.93e-04	13	52	2	CID000126171
Drug	NSC 255110	HSP90AA1 HSP90AA2P	3.93e-04	13	52	2	CID000318505
Drug	AC1L3HJJ	HSP90AA1 HSP90AA2P	3.93e-04	13	52	2	CID000089287
Drug	FLT3 inhibitor	HSP90AA1 HSP90AA2P	4.57e-04	14	52	2	CID001048845
Drug	FG 1	HSP90AA1 HSP90AA2P	4.57e-04	14	52	2	CID005288213
Disease	serum gamma-glutamyl transferase measurement	TRAF3 RBM25 ARHGAP10 SLCO1A2 ZFP91 PSD3 HMGB1 CCDC50 CGNL1 USP16 TOP1	2.36e-07	914	49	11	EFO_0004532
Disease	X-linked mental retardation with cerebellar hypoplasia and distinctive facial appearance (implicated_via_orthology)	ARHGAP10 ARHGAP26	1.62e-05	4	49	2	DOID:0080311 (implicated_via_orthology)
Disease	pulse pressure measurement	ASAP2 RBM25 CLGN NEBL ARHGAP26 FER ANKRD11 INO80 LACTB	4.20e-04	1392	49	9	EFO_0005763
Disease	cortex volume change measurement, age at assessment	CGNL1 TOP1	9.93e-04	28	49	2	EFO_0008007, EFO_0021500
Disease	cancer (implicated_via_orthology)	RBBP6 TOP1 HSP90AA1 HSP90AA2P	1.02e-03	268	49	4	DOID:162 (implicated_via_orthology)
Disease	chronic rhinosinusitis	CYLC2 IL33	1.46e-03	34	49	2	EFO_1000024
Disease	QRS duration	TCEA3 NEBL FER MYBPC2	1.51e-03	298	49	4	EFO_0005055
Disease	grey matter volume measurement	PSD3 HMGB1P1	2.44e-03	44	49	2	EFO_0005420
Disease	caudate nucleus measurement, functional brain measurement, response to reward	CYLC2 PSD3	2.78e-03	47	49	2	EFO_0007849, EFO_0008387, EFO_0008396
Disease	atrial fibrillation	NEBL ARHGAP10 ARHGAP26 CGNL1	3.34e-03	371	49	4	EFO_0000275

Protein segments in the cluster

Peptide	Gene	Start	Entry
IKNKLDKEKDKDEKY	ARID4B	641	Q4LE39
KISKEKEKIFKEDKE	ANKRD11	786	Q6UB99
KEDKEKLKKEKVYRE	ANKRD11	796	Q6UB99
KEKKDKESTEKYKDR	ANKRD11	1206	Q6UB99
AKKEKAEKKEKGEDY	ANKRD11	1366	Q6UB99
AEEKKAYKKAKEREK	CCDC50	211	Q8IVM0
SKEKDKEKGKEEKVK	CFAP46	1386	Q8IYW2
SKKGKDIEKGKEEKL	CYLC2	141	Q14093
NDGKEKYEKEKIKSI	AASDH	156	Q4L235
EKEKHKKEIEGEKEK	ANKRD12	661	Q6UB98
KKEIEGEKEKYKTKD	ANKRD12	666	Q6UB98
GEKEKYKTKDSAKEL	ANKRD12	671	Q6UB98
KEKYEADLKKEIKKL	CNOT3	41	O75175
KEIAKKKNDKKEAYV	RAD51AP2	276	Q09MP3
DTHKKLEEEKGKKEK	RBM25	286	P49756
REKYAEKKKKEDELD	INO80	1301	Q9ULG1
AVKEEKKKFDKETEK	ARHGAP10	126	A1A4S6
SKDEVKAYLKKEFEK	FKBP14	156	Q9NWM8
KKAAKLKEKYEKDIA	HMGB1	146	P09429
KDYETKITKIEKEKK	ASAP2	151	O43150
DIKKVKEEKAYKALK	LACTB	226	P83111
EYREKGKEKDKDAKK	MACO1	251	Q8N5G2
KDDKKKDTKKYPEST	CYLC1	356	P35663
EKGDKKEGKDVKVKE	HMGN5	216	P82970
VKKTLDGELDEKYKK	LAMB1	1686	P07942
KKEYKEDLEKSKIKT	PAXBP1	136	Q9Y5B6
KEEKVKKDYSKDVKS	RBBP6	1106	Q7Z6E9
KGKEKKKKEAEEEDE	NUTM1	1001	Q86Y26
KCKQDVLKTKEKYEK	PACSIN2	196	Q9UNF0
YVEDLKKDEKKDKVL	IL33	146	O95760
KEEEKKKYYDTKIED	CASP5	96	P51878
KGDEAKAKETLKKYE	CGNL1	856	Q0VF96
KEKYKEALAKGKETE	FER	151	P16591
EMKIKEEGYKKEISK	CCDC152	121	Q4G0S7
EEDKFDKEEYRKKIK	DDX10	731	Q13206
KKKKIKEKYIDQEEL	HSP90AA1	276	P07900
DGDKKKKKTKEKYID	HSP90AA2P	271	Q14568
EEKEKKKKKKGTAEE	OTOF	1301	Q9HC10
KKEEKKTKTIEEVYM	FAM114A1	431	Q8IWE2
KDVLSEKEKKLEEYK	RPRD1B	266	Q9NQG5
KKAAKLKEKYEKDIA	HMGB1P1	146	B2RPK0
AAKEAKKKYDKETEK	ARHGAP26	126	Q9UNA1
KKKYLEDIESVKKKN	POTEJ	636	P0CG39
EKKESKDTKKIEGKD	SLTM	511	Q9NWH9
KEEVKKEKYGITKDF	SLCO1A2	291	P46721
VKKKHKDTEYKKTDI	CLGN	496	O14967
EKFVKTVEDKYKCEK	TRAF3	41	Q13114
EELKNKVKDYEKKKS	USP16	336	Q9Y5T5
KYDKDIKKEKDKGKA	SEC62	101	Q99442
KKKDGEKEESKKEET	SEC62	141	Q99442
KGEKGEEREKAKKKE	TCEA3	86	O75764
GGEKIKKKKKDDTYD	UBN1	196	Q9NPG3
GKVKEEKEKKEIKVE	ZFP91	251	Q96JP5
DKKVKAKDVDEYKLK	PSD3	956	Q9NYI0
DYKPKKIKTEDTKKE	TOP1	146	P11387
EEEEKAKAYKKEKQK	ZMAT2	151	Q96NC0
EEKKKKKKDDDDLGI	MYBPC2	196	Q14324
EKEYKKDLESIIKGK	NEBL	446	O76041