Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein-glutamine gamma-glutamyltransferase activity

TGM1 TGM2

3.42e-059202GO:0003810
GeneOntologyMolecularFunctionmethyl-CpG binding

MBD3 MBD1

4.36e-0431202GO:0008327
GeneOntologyBiologicalProcesscellular response to vitamin

CYP27B1 PENK GAS6

3.44e-0631203GO:0071295
GeneOntologyBiologicalProcesscellular response to nutrient

CYP27B1 PENK GAS6

1.98e-0555203GO:0031670
GeneOntologyBiologicalProcessresponse to vitamin

CYP27B1 PENK GAS6

1.19e-04100203GO:0033273
GeneOntologyBiologicalProcessresponse to nutrient levels

MBD3 MBD1 CYP27B1 PENK GAS6

1.68e-04566205GO:0031667
GeneOntologyBiologicalProcesscellular response to vitamin D

CYP27B1 PENK

2.23e-0423202GO:0071305
GeneOntologyBiologicalProcessresponse to estradiol

MBD3 MBD1 PENK

2.46e-04128203GO:0032355
GeneOntologyBiologicalProcesspeptide cross-linking

TGM1 TGM2

3.09e-0427202GO:0018149
Domain-

MBD3 MBD1

3.04e-0582023.30.890.10
DomainTransglut_N

TGM1 TGM2

3.90e-059202PF00868
DomainTRANSGLUTAMINASES

TGM1 TGM2

3.90e-059202PS00547
DomainTransglutaminase_N

TGM1 TGM2

3.90e-059202IPR001102
DomainGln_gamma-glutamylTfrase_euk

TGM1 TGM2

3.90e-059202IPR023608
DomainTransglutaminase_AS

TGM1 TGM2

3.90e-059202IPR013808
DomainTransglut_C

TGM1 TGM2

3.90e-059202PF00927
Domain-

TGM1 TGM2

3.90e-0592023.90.260.10
DomainTransglutaminase_C

TGM1 TGM2

4.88e-0510202IPR008958
DomainTGc

TGM1 TGM2

5.96e-0511202SM00460
DomainTransglut_core

TGM1 TGM2

5.96e-0511202PF01841
DomainMethyl_CpG_DNA-bd

MBD3 MBD1

5.96e-0511202IPR001739
DomainMBD

MBD3 MBD1

5.96e-0511202PF01429
DomainTransglutaminase-like

TGM1 TGM2

5.96e-0511202IPR002931
DomainMBD

MBD3 MBD1

5.96e-0511202SM00391
DomainMBD

MBD3 MBD1

5.96e-0511202PS50982
DomainDNA-bd_dom

MBD3 MBD1

5.96e-0511202IPR016177
DomainLAM_G_DOMAIN

GAS6 CELSR3

7.48e-0438202PS50025
DomainLaminin_G_2

GAS6 CELSR3

8.29e-0440202PF02210
DomainLamG

GAS6 CELSR3

1.00e-0344202SM00282
DomainLaminin_G

GAS6 CELSR3

1.74e-0358202IPR001791
Domain-

GAS6 CELSR3

4.58e-03952022.60.120.200
DomainASX_HYDROXYL

GAS6 CELSR3

5.06e-03100202PS00010
DomainIg_E-set

TGM1 TGM2

5.47e-03104202IPR014756
DomainEGF-type_Asp/Asn_hydroxyl_site

GAS6 CELSR3

5.67e-03106202IPR000152
DomainEGF_CA

GAS6 CELSR3

7.45e-03122202SM00179
DomainEGF-like_Ca-bd_dom

GAS6 CELSR3

7.68e-03124202IPR001881
DomainEGF

GAS6 CELSR3

7.92e-03126202PF00008
DomainConA-like_dom

GAS6 CELSR3

2.26e-02219202IPR013320
DomainEGF

GAS6 CELSR3

2.58e-02235202SM00181
DomainEGF_3

GAS6 CELSR3

2.58e-02235202PS50026
Pubmed

Variations in both TG1 and TG2 isozyme-specific in situ activities and protein expressions during mouse embryonic development.

TGM1 TGM2

3.14e-07220223896968
Pubmed

Identification of human salivary transglutaminases.

TGM1 TGM2

3.14e-07220222080209
Pubmed

In situ detection of active transglutaminases for keratinocyte type (TGase 1) and tissue type (TGase 2) using fluorescence-labeled highly reactive substrate peptides.

TGM1 TGM2

3.14e-07220220876521
Pubmed

Isozyme-specific comprehensive characterization of transglutaminase-crosslinked substrates in kidney fibrosis.

TGM1 TGM2

3.14e-07220229743665
Pubmed

Transglutaminase autoantibodies in dermatitis herpetiformis and celiac sprue.

TGM1 TGM2

3.14e-07220217762854
Pubmed

Transglutaminases and transglutaminase-catalyzed cross-links colocalize with the pathological lesions in Alzheimer's disease brain.

TGM1 TGM2

3.14e-07220218673368
Pubmed

Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation.

TGM1 TGM2

3.14e-07220222573678
Pubmed

Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter.

TGM1 TGM2

3.14e-0722028626785
Pubmed

Low prevalence of IgA anti-transglutaminase 1, 2, and 3 autoantibodies in children with atopic dermatitis.

TGM1 TGM2

9.42e-07320224885370
Pubmed

Gene disruption of tissue transglutaminase.

TGM1 TGM2

9.42e-07320211113189
Pubmed

Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans.

TGM1 TGM2

9.42e-07320227649154
Pubmed

Assessment of expression and specific activities of transglutaminases TG1, TG2, and FXIII-A during osteoclastogenesis.

TGM1 TGM2

9.42e-07320231786225
Pubmed

Genetic association study between methyl-CpG-binding domain genes and schizophrenia among Chinese family trios.

MBD3 MBD1

9.42e-07320224849540
Pubmed

Role of DNA methylation and methyl-DNA binding proteins in the repression of 5-lipoxygenase promoter activity.

MBD3 MBD1

9.42e-07320219781662
Pubmed

Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression.

MBD3 MBD1

9.42e-07320214610093
Pubmed

Mutant huntingtin protein: a substrate for transglutaminase 1, 2, and 3.

TGM1 TGM2

9.42e-07320215715085
Pubmed

Transglutaminase and clusterin induction during normal and abnormal limb development in the mouse.

TGM1 TGM2

1.88e-0642028828830
Pubmed

EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation.

TGM1 TGM2

1.88e-06420220080707
Pubmed

Lack of 'tissue' transglutaminase protein cross-linking leads to leakage of macromolecules from dying cells: relationship to development of autoimmunity in MRLIpr/Ipr mice.

TGM1 TGM2

1.88e-06420216465267
Pubmed

Regulated expression of tissue transglutaminase in Swiss 3T3 fibroblasts: effects on the processing of fibronectin, cell attachment, and cell death.

TGM1 TGM2

1.88e-0642029511731
Pubmed

Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase).

TGM1 TGM2

3.14e-0652029448282
Pubmed

Identification and characterization of a family of mammalian methyl-CpG binding proteins.

MBD3 MBD1

3.14e-0652029774669
Pubmed

Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA.

MBD3 MBD1

3.14e-06520211371345
Pubmed

Identification of imprinting regulators at the Meg3 differentially methylated region.

MBD3 MBD1

3.14e-06520222709555
Pubmed

Characterization of TG2 and TG1-TG2 double knock-out mouse epidermis.

TGM1 TGM2

3.14e-06520227864691
Pubmed

Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development.

MBD3 MBD1

3.14e-06520217546630
Pubmed

Knocking-in the R142C mutation in transglutaminase 1 disrupts the stratum corneum barrier and postnatal survival of mice.

TGM1 TGM2

4.71e-06620222258055
Pubmed

Identification and characterization of human cDNAs specific to BCS1, PET112, SCO1, COX15, and COX11, five genes involved in the formation and function of the mitochondrial respiratory chain.

GATB COX11

4.71e-0662029878253
Pubmed

Evolution of transglutaminase genes: identification of a transglutaminase gene cluster on human chromosome 15q15. Structure of the gene encoding transglutaminase X and a novel gene family member, transglutaminase Z.

TGM1 TGM2

6.59e-06720211390390
Pubmed

HIV-1 gp120-dependent induction of apoptosis in antigen-specific human T cell clones is characterized by 'tissue' transglutaminase expression and prevented by cyclosporin A.

TGM1 TGM2

8.78e-0682027906657
Pubmed

Diversity of two forms of DNA methylation in the brain.

MBD3 MBD1

8.78e-06820224653733
Pubmed

Human-immunodeficiency-virus transmembrane glycoprotein gp41 is an amino acceptor and donor substrate for transglutaminase in vitro.

TGM1 TGM2

8.78e-0682027688299
Pubmed

Genomic structure and chromosomal mapping of the murine and human Mbd1, Mbd2, Mbd3, and Mbd4 genes.

MBD3 MBD1

2.44e-051320210441743
Pubmed

The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2.

MBD3 MBD1

2.44e-051320212124384
Pubmed

Single cell RT-PCR on mouse embryos: a general approach for developmental biology.

MBD3 MBD1

2.44e-051320220300987
Pubmed

Multiplex rt-PCR expression analysis of developmentally important genes in individual mouse preimplantation embryos and blastomeres.

MBD3 MBD1

3.75e-051620218784354
Pubmed

The transcription factor Otx2 regulates choroid plexus development and function.

TGM2 PENK

1.64e-043320223364326
Pubmed

Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.

TGM2 DNAJC13 MBD1

2.92e-0422820330471916
Pubmed

Nolz1 expression is required in dopaminergic axon guidance and striatal innervation.

PENK CELSR3

4.58e-045520232561725
Pubmed

Targeted inhibition of ubiquitin signaling reverses metabolic reprogramming and suppresses glioblastoma growth.

COX11 ATP6AP1

4.75e-045620235918402
GeneFamilyTransglutaminases

TGM1 TGM2

2.63e-059162773
GeneFamilyZinc fingers CXXC-type|Methyl-CpG binding domain containing

MBD3 MBD1

4.02e-05111621025
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGIR CACNA1H RRAD GAS6

1.54e-061942043cffb5c58f6d5bd254f39ee9c41b7e1e4da0ff75
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PTGIR CACNA1H RRAD GAS6

1.60e-06196204c373465e34e2dd581247962d59e0477aae877079
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PTGIR CACNA1H RRAD GAS6

1.60e-061962048b5337ccf74de90e8b89a02ac00671af1de2cfff
ToppCellcellseq-Mesenchymal-Myocytic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PTGIR CACNA1H RRAD GAS6

1.70e-0619920420e62a7029fa0d214244cdf2a481fc5d78290438
ToppCelldistal-mesenchymal-Pericyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTGIR CACNA1H RRAD GAS6

1.70e-06199204000d9b5f5a48e56f0733390adb3d7270c49a4a1a
ToppCelldistal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTGIR CACNA1H RRAD GAS6

1.74e-06200204911db29f254bb697610e720ba78816e2c7f57933
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PTGIR CACNA1H RRAD GAS6

1.74e-062002040c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PTGIR CACNA1H RRAD GAS6

1.74e-0620020494f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTGIR CACNA1H RRAD GAS6

1.74e-06200204522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

SPIB CYP27B1 GAS6

5.47e-05167203bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

SPIB CYP27B1 GAS6

5.56e-05168203968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPIB PTGIR RRAD

6.07e-0517320309a13407a41ff2cba82fc417b72bf9a24ce6c42e
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPIB PTGIR RRAD

6.07e-05173203bfec038a6783f166240da4861e100643c6ea80a5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AQP6 ATP6AP1 GAS6

6.17e-05174203d81a5e767e8882ebca4678af881c94c062f8cea5
ToppCelldroplet-Heart-4Chambers-21m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H RRAD GAS6

6.17e-05174203f098778ea74012861ec74b425e45776a31f67679
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGM2 CACNA1H GAS6

6.61e-05178203a107dd98a07086ed0429116095ecda60c9dbef1e
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGM2 ATP6AP1 GAS6

6.61e-05178203c85de851b39cb8ef7ea1866ab64c6a387788273a
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_33|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGM2 ATP6AP1 GAS6

6.72e-0517920313d80ae2e43a5daad0aeb5f47338efca2c58800a
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPIB PTGIR GAS6

6.72e-0517920342f3c040f504a91cc69292d39d22b5715c12526f
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPIB PTGIR GAS6

6.72e-05179203063c05753ef1b4a18bc1ebbcae62c8cd25d11070
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPIB PTGIR GAS6

6.83e-0518020332d871738a24071b70084a7e80148a516110c78b
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPIB PTGIR GAS6

6.83e-05180203067ca8a15228c7f3b3bc7aecbc9b1611ca05e176
ToppCell10x5'-Lung-Myeloid_Dendritic-migDC|Lung / Manually curated celltypes from each tissue

SPIB PTGIR GAS6

6.83e-05180203e9e8992deb0beeee5548910e4616e7c990763d99
ToppCellnormal_Lung-Fibroblasts-Pericytes|normal_Lung / Location, Cell class and cell subclass

PTGIR CACNA1H GAS6

6.94e-05181203f74941e49950027360d71ea3b205fc20c6929766
ToppCellCTRL-Myeloid-cDC|Myeloid / Disease state, Lineage and Cell class

SPIB PTGIR GAS6

7.06e-05182203ee137574b8f0e684a4a7cb26226877c471cae433
ToppCellCTRL-Myeloid-cDC|CTRL / Disease state, Lineage and Cell class

SPIB PTGIR GAS6

7.17e-0518320320c4d16de7e090df3556a4458f783383a26871b6
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TGM2 RRAD GAS6

7.65e-051872031aebf6fab40b96f2f5feb77a302bb805838fccf3
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTGIR CACNA1H RRAD

7.65e-0518720386250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell15-Distal-Mesenchymal-Pericyte|Distal / Age, Tissue, Lineage and Cell class

PTGIR RRAD GAS6

7.77e-051882034963382e54aac06bf5047c7d725393db70667ee7
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MBD3 RRAD GAS6

7.77e-05188203c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1H RRAD GAS6

7.77e-05188203ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellStriatum-Endothelial|Striatum / BrainAtlas - Mouse McCarroll V32

PTGIR TGM2 RRAD

7.89e-0518920395ee3b6d7fbbfcf91c780dfcd0926acec05f0a2d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AQP6 ATP6AP1 GAS6

8.14e-051912038b34e06c398056e857a10c7653c70c0b1f181692
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGIR CACNA1H GAS6

8.14e-05191203716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGIR CACNA1H GAS6

8.14e-051912031626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCellMild-Myeloid-mDC-|Mild / Condition, Lineage, Cell class and cell subclass

SPIB PTGIR GAS6

8.27e-051922038520b3fdf4508ac66f7918da613abc928ab5832a
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTGIR CACNA1H RRAD

8.27e-0519220388472b99970ba0decbf87164fc241a1c77b3b389
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTGIR CACNA1H RRAD

8.27e-05192203dee97f650ae6f4d07a142ade402aae1905791a22
ToppCell356C-Myeloid-Dendritic-cDC2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SPIB PTGIR GAS6

8.27e-05192203a7ccbea7c90c070d279d7ad3f2b5b7c0e3efd890
ToppCellMild-Myeloid-mDC|Mild / Condition, Lineage, Cell class and cell subclass

SPIB PTGIR GAS6

8.27e-05192203da3952bd5c96242c15eb76678d0608ae2926a16e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPIB PTGIR GAS6

8.27e-051922032c69f3f388b69fb1c1968c923cdbab90658883dd
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1H RRAD GAS6

8.27e-051922035000440dc1ed17e7474d340921bdff945646f27e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPIB PTGIR GAS6

8.27e-05192203d5a7b546ebfb2e757dd9c64cb1b651f6ed0e0fc7
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGIR CACNA1H GAS6

8.40e-0519320341ea268e7697101fe70d8ef1045f3a43b9311739
ToppCellPBMC-Control-cDC_5|Control / Compartment, Disease Groups and Clusters

SPIB ATP6AP1 GAS6

8.40e-0519320353ddee444dcfb9fe568e9e8fb64bc8304c262530
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGIR CACNA1H GAS6

8.40e-05193203b2abe939027a69b60d83a28d4d4cc53ba1dee4c5
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGIR CACNA1H GAS6

8.40e-05193203d75f334fe3d9f39ef02a5de0f8202f7a761a8fc8
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGIR CACNA1H GAS6

8.53e-051942038f19e553f18c313c2a2ff9453884b9484b255d71
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGIR CACNA1H GAS6

8.53e-05194203f95935153bd2c4c3c7b2b729da6f7e98b45fed79
ToppCellP15-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PENK RRAD GAS6

8.53e-051942035f04d21c4e2d36e74b6c5889aa97fd98f75a0973
ToppCell11.5-Distal-Mesenchymal-Pericyte|Distal / Age, Tissue, Lineage and Cell class

PTGIR RRAD GAS6

8.53e-0519420308701590496cf85ff790e54a81493c61177e76ff
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGIR CACNA1H GAS6

8.53e-0519420367fbb81b7d20cb63be27b2a2beea5b5689f8e08c
ToppCell3'_v3-Lung-Myeloid_Dendritic|Lung / Manually curated celltypes from each tissue

SPIB PTGIR GAS6

8.66e-05195203b748cb15846345363e8c2ee5936bb42bba3ba9a7
ToppCellBAL-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPIB PTGIR GAS6

8.66e-051952039e5cf33b5dd455efa464a63d7116786c0786aefd
ToppCellBAL-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPIB PTGIR GAS6

8.66e-051952036ba23e19801305e071b0e4aaf1ee6f53f3b027d3
ToppCelldroplet-Mammary_Gland-nan-18m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATB TGM2 GAS6

8.66e-05195203c771ac1db8bd5f3a80bd3484094a58c28983f97b
ToppCellMild_COVID-19-Myeloid-cDC|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

SPIB PTGIR GAS6

8.66e-0519520324149bb6933135b1a0a5c7f505914942b3782c3a
ToppCellBAL-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPIB PTGIR GAS6

8.66e-0519520366e5fd9f3208a06d617c5e994822bf57dceae7e2
ToppCellBAL-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPIB PTGIR GAS6

8.66e-051952037209babdff96c93cd52cfe5d5cfd7e3c0274d8dd
ToppCelldroplet-Bladder-nan-24m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTGIR CACNA1H RRAD

8.79e-051962039a90dd26e7a43e3fd55e7c5d8354cfa4cdd5a6cc
ToppCellILEUM-non-inflamed-(8)_Pericytes|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PTGIR CACNA1H RRAD

8.79e-05196203b98fe1519e420d8b03c66e164bf4544f3dbb2e44
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTGIR CACNA1H RRAD

8.79e-0519620304dfef1bd4ebb0e9469ae80024dc177e469a2560
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGIR CACNA1H GAS6

8.92e-0519720301249bd485a3734de87ae6ed9c749597f39c6335
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Pericytes|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PTGIR CACNA1H RRAD

8.92e-05197203608328608cef82adc867a449216839622253d486
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTGIR CACNA1H RRAD

8.92e-05197203488e85991c5e668afb7672942726d9295b8fc7d8
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TGM2 CACNA1H RRAD

9.06e-05198203f261a37dd07976548b897af86df1d1a0dc069889
ToppCellParenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPIB PTGIR CYP27B1

9.19e-05199203f4ab29f99ce45a3044d2e9f356dc24d3c5e7121f
ToppCelldistal-mesenchymal-Pericyte-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTGIR RRAD GAS6

9.19e-05199203e72ac7a00405cde06293d7adac7dc40eb0cf87ba
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TGM2 CACNA1H RRAD

9.19e-05199203b1753474152b82a0b811b9878c890a359e14919a
ToppCellmedial-mesenchymal-Pericyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACNA1H RRAD GAS6

9.33e-05200203bbda454260016be92b539e220ecf7bcbbc6139e4
ToppCellmedial-2-mesenchymal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTGIR RRAD GAS6

9.33e-05200203a9d8aa5bcf383d98a9e2eaf4b1f8466982d6b088
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTGIR CACNA1H RRAD

9.33e-0520020343b76e382b38b9856c07557a75e5b1ce0cee1d9e
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PTGIR CACNA1H GAS6

9.33e-05200203600d56257b1b0cda8ed2fd0db92c6551711f7d6d
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1H RRAD GAS6

9.33e-05200203d70bad979299615fcba707ba21296020918705e6
ToppCelldistal-mesenchymal-Pericyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACNA1H RRAD GAS6

9.33e-05200203867935701fac71a3fe01578362da0676f959736c
ToppCell390C-Myeloid-Dendritic|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SPIB PTGIR GAS6

9.33e-052002033935b6ff3ae32d170a268538c756ee34ed2308d4
ToppCellmedial-mesenchymal-Pericyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACNA1H RRAD GAS6

9.33e-05200203f36d7cb6345daccebf76997f998e35d959b59452
ToppCelldistal-mesenchymal-Pericyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACNA1H RRAD GAS6

9.33e-05200203fe31287cfb51d45643bdedbaa5efc03ed87263c6
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PTGIR CACNA1H GAS6

9.33e-052002038158f4eaeff945a6788c8e732b7a1b0d78052a06
ToppCellmedial-mesenchymal|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTGIR RRAD GAS6

9.33e-052002034f19e1e40966e27779bf77e8c170ed3ecc24353e
ToppCelldistal-1-mesenchymal-Pericyte|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTGIR RRAD GAS6

9.33e-05200203ff205afda57b9267016f0c937445da1b0266af9b
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1H RRAD GAS6

9.33e-0520020338c21ec379005f688df33aea65237a063c476c2e
ToppCellParenchyma_COVID-19-Stromal-TX-Smooth_muscle-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PTGIR CACNA1H RRAD

9.33e-0520020378e9a40153d7ba5d9ea6393a37d26fc5c0220867
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PTGIR CACNA1H RRAD

9.33e-05200203c46e06b4f22d3456e67bc62a9ac198e8041965ad
ToppCellmedial-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACNA1H RRAD GAS6

9.33e-052002039820fb4f6efcdfc6de937ef2302a98b48426baa3
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Gfra1|Hippocampus / BrainAtlas - Mouse McCarroll V32

SPIB AQP6

3.06e-0458202a58f4ee94896c1f790335245163179f52705fae7
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Gfra1-Inhibitory_Neuron.Gad1Gad2_Pvalb.Gfra1_(Interneuron,_Basket_1)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

SPIB AQP6

3.06e-0458202f058992ac3c6c3bd56ff0d1e0c9de1d61e15b387
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Gfra1-Inhibitory_Neuron.Gad1Gad2_Pvalb.Gfra1_(Interneuron,_Basket_1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SPIB AQP6

3.06e-0458202f9971c7e50844116d831be1c47fce1d213ac7228
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-Rorb_(Nucleus_of_the_lateral_olfactory_tract_(LOT))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

AQP6 CYP27B1

4.20e-04682026945089858778301a05ecc5895310d768768758c
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-Rorb_(Nucleus_of_the_lateral_olfactory_tract_(LOT))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

AQP6 CYP27B1

4.20e-0468202ac9d0f473c878b96a422bbdd7088eb8125574dde
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2-Excitatory_Neuron.Slc17a7.Tac2.Chat_(Habenular_cholinergic_cells)|Thalamus / BrainAtlas - Mouse McCarroll V32

AQP6 SLC38A8

6.10e-048220251dd9ab3ddb26d3d3395d0c1a156a12a86caf89b
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Acta2Rgs5.Acta2_(Mural.Acta2Rgs5.Acta2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PTGIR CYP27B1

7.34e-0490202d809ebc50917aaf13e693b21c8faa399103e7abe
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Acta2Rgs5.Acta2_(Mural.Acta2Rgs5.Acta2)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PTGIR CYP27B1

7.34e-04902026b94b1b05d45ecdc2ac9d5445d244dac96d60c22
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PTGIR RRAD

8.87e-04992028aab2a6989d342af387bd0823f79e7b326a12430
ToppCelldroplet-Heart-nan-18m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPIB CELSR3

9.79e-04104202060f0baca239ab89c18be40c1aa31931f4791b62
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Fos_(Mural.Rgs5Acta2.Fos)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PTGIR RRAD

9.97e-0410520273639bfa677c7bb9e5166aa09eabaf1b05bb89a0
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Fos_(Mural.Rgs5Acta2.Fos)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PTGIR RRAD

9.97e-0410520284b639eb44f71d1e12bb7850b9063d80e73cb741
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Lmcd1_(Mural.Rgs5Acta2.Lmcd1)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PTGIR RRAD

1.04e-031072020b45241cc52d10225966b49941efb66997184158
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Lmcd1_(Mural.Rgs5Acta2.Lmcd1)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PTGIR RRAD

1.04e-031072022f84089acc794b43ee59452dc8f90ca7261ebd41
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PTGIR RRAD

1.30e-03120202a320799ab5f2ce872e038b15841a23174c5436e8
DrugCh 80

TGM1 TGM2

7.33e-072202ctd:C098137
DrugVitamin K

TGM2 RRAD GAS6

4.06e-0636203ctd:D014812
Drugsuosan

TGM2 NAGA

4.39e-064202CID000008803
Drugrifampicin

TGM1 TGM2 MBD1 CYP27B1 PENK

5.58e-06306205CID005381226
DrugZ-Gln-Gly

TGM1 TGM2

7.32e-065202CID000302424
Drugalitame

TGM2 NAGA

1.54e-057202CID000064763
Drugcoumarin 7

TGM1 TGM2

1.54e-057202CID000094381
DrugCTK3D1047

AQP6 MBD3 MBD1

1.73e-0558203CID013293130
Drug4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid

TGM1 TGM2

2.05e-058202ctd:C064545
Drugdidansylcadaverine

TGM1 TGM2

2.05e-058202CID000108731
Drugn-propylacrylamide

TGM1 TGM2

2.05e-058202CID000114794
Drug5230742; Up 200; 17uM; MCF7; HT_HG-U133A_EA

MBD3 CACNA1H MBD1 CELSR3

2.05e-05190204970_UP
DrugWY-14643; Up 200; 100uM; MCF7; HG-U133A

GATB AQP6 MBD3 CELSR3

2.27e-05195204368_UP
DrugTremorine dihydrochloride [300-68-5]; Down 200; 15uM; MCF7; HT_HG-U133A

GATB MBD1 CYP27B1 GAS6

2.32e-051962046273_DN
Drugchrysamine

TGM1 TGM2 PENK

2.33e-0564203CID006011258
DrugTracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; PC3; HT_HG-U133A

SPIB TGM2 PENK CELSR3

2.36e-051972046619_UP
Drugtroglitazone; Down 200; 10uM; SKMEL5; HG-U133A

GATB TGM2 MBD3 MBD1

2.41e-05198204504_DN
DrugDGM-2

TGM1 TGM2

2.63e-059202CID000016891
Drugradicicol

TGM1 TGM2 RRAD GAS6

2.66e-05203204CID000005033
Drug3,5-di-tert-butylchalcone 4'-carboxylic acid

TGM1 TGM2

3.28e-0510202ctd:C054189
DrugAC1L1FHZ

TGM1 PTGIR TGM2 PENK

3.33e-05215204CID000003244
Drugdapsone

TGM1 TGM2 MBD1

3.47e-0573203CID000002955
Drugguanidinium-phosphate

TGM1 TGM2

4.01e-0511202CID000160593
Drug1-(5-aminopentyl)-3-phenylthiourea

TGM1 TGM2

4.01e-0511202CID003035524
DrugAC1L97MU

TGM1 TGM2 PENK

4.07e-0577203CID000414413
Drugterbutryn

TGM1 TGM2 PENK

4.56e-0580203CID000013450
DrugTg 5

TGM1 TGM2

4.81e-0512202CID000205491
Druggossypol

TGM1 TGM2 CACNA1H PENK

5.71e-05247204CID000003503
Drug5-(biotinamido)pentylamine

TGM1 TGM2

6.63e-0514202CID000083906
Drugcyclopropylmethyl

ATP6AP1 PENK

9.89e-0517202CID000080245
Drugmonodansylthiacadaverine

TGM1 TGM2

9.89e-0517202CID000162694
Drugphenylacetylene

ATP6AP1 PENK

1.38e-0420202CID000010821
DrugCymarigenen

PTGIR NAGA

1.38e-0420202CID000005303
Drugphloroglucinol

ATP6AP1 PENK

1.52e-0421202CID000000359
DrugNpys

PTGIR PENK

1.52e-0421202CID000129283
DrugAC1Q5T5H

MBD1 NAGA

1.52e-0421202CID000005721
DrugAC1L510Y

TGM1 PTGIR

1.68e-0422202CID000196040
DrugSpotlight

TGM1 TGM2 PENK

1.76e-04126203CID000086222
Drugtryptophanyl-5'AMP

TGM2 ATP6AP1

1.83e-0423202CID000446202
Drugchloranil

TGM1 ATP6AP1

2.00e-0424202CID000008371
DrugDMAB

TGM1 TGM2 PENK

2.07e-04133203CID000006053
Drug3-methyladenine

TGM1 TGM2 PENK

2.11e-04134203CID000001673
Drugbaryta

CACNA1H PENK RRAD

2.21e-04136203CID000062392
DrugNSC71948

TGM1 TGM2 PENK

2.30e-04138203CID000415676
Drug2-nitroaniline

TGM1 TGM2 PENK

2.35e-04139203CID000006946
Drugglycine ethyl ester

TGM1 TGM2

2.35e-0426202CID000012175
Drugoxazole

PTGIR ATP6AP1

2.35e-0426202CID000009255
Drugpentafluorobenzyl alcohol

TGM1 RRAD

2.54e-0427202CID000009923
Drugbenzylamide

TGM1 RRAD

2.54e-0427202CID000010391
DrugC4:1n-2

ATP6AP1 PENK

2.73e-0428202CID000019499
DrugTexas Red

TGM1 TGM2

2.73e-0428202CID000452705
Drugpyroantimonate

AQP6 MBD1

2.73e-0428202CID006327644
Drug5(G)-TASP

ATP6AP1 PENK

2.93e-0429202CID000488931
DrugI-As

TGM1 TGM2 PENK

3.43e-04158203CID000078017
DrugAC1L1H88

TGM1 CYP27B1

3.58e-0432202CID000004018
DrugII P

TGM1 ATP6AP1

3.58e-0432202CID000449430
Drugchlorothalonil

COX11 TGM1 PENK

3.69e-04162203CID000015910
DrugTG-3

TGM1 TGM2

3.81e-0433202CID000205489
DrugCD367

TGM1 TGM2

3.81e-0433202CID000119342
DrugAC1L1GZB

PTGIR MBD3 MBD1

4.03e-04167203CID000003908
Drug1pzj

PTGIR MBD1 ATP6AP1

4.03e-04167203CID000447976
Drughypusine

TGM1 TGM2

4.04e-0434202CID000065396
Drugsilver nanoparticles

TGM1 TGM2 PENK

4.39e-04172203CID000023954
DrugAC1L2U9H

TGM1 CYP27B1

4.54e-0436202CID000077996
DrugL-165041

TGM1 PTGIR

4.54e-0436202CID006603901
Drugphenylquinone

PENK NAGA

4.54e-0436202CID000009688
DrugTripeptide derivative, 14

PTGIR ATP6AP1

4.54e-0436202CID009918384
Druglithocholyltaurine

TGM1 TGM2 PENK

4.62e-04175203CID000010595
DrugKSCN

TGM2 PENK

4.79e-0437202CID000516872
DrugCompound 10

ATP6AP1 NAGA

4.79e-0437202CID003749170
Drug3-nitropropionic acid

TGM1 TGM2 PENK

4.86e-04178203CID000001678
Drugquinolinic acid

TGM1 TGM2 PENK

4.94e-04179203CID000001066
Drugresveratrol; Up 200; 10uM; MCF7; HT_HG-U133A_EA

TGM2 MBD1 GAS6

5.02e-04180203958_UP
Drugcystamine

TGM1 TGM2 PENK

5.10e-04181203CID000002915
Drugliarozole

TGM1 ATP6AP1

5.33e-0439202CID000060652
DrugCTK8G2960

TGM1 TGM2 PENK

5.52e-04186203CID005361912
Drugp-phenylenediamine

ATP6AP1 NAGA

5.60e-0440202CID000007814
DrugPepstatin A [26305-03-3]; Up 200; 5.8uM; HL60; HT_HG-U133A

MBD3 PENK CELSR3

5.96e-041912031328_UP
DrugHomochlorcyclizine dihydrochloride [1982-36-1]; Up 200; 10.4uM; MCF7; HT_HG-U133A

MBD3 CACNA1H MBD1

5.96e-041912037417_UP
Drugtroglitazone; Down 200; 10uM; PC3; HG-U133A

TGM2 NAGA GAS6

6.15e-04193203462_DN
DrugManNAc-6-P

ATP6AP1 NAGA

6.18e-0442202CID000000898
Drugglutamin

GATB TGM1 TGM2 PENK

6.21e-04461204CID000000738
Drug(+/-)-blebbistatin; Up 200; 17uM; MCF7; HT_HG-U133A_EA

CACNA1H MBD1 CELSR3

6.24e-04194203954_UP
DrugProcarbazine hydrochloride [366-70-1]; Up 200; 15.6uM; MCF7; HT_HG-U133A

SPIB MBD3 CACNA1H

6.33e-041952035452_UP
DrugDihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; MCF7; HT_HG-U133A

AQP6 CACNA1H GAS6

6.33e-041952032895_UP
DrugLobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A

MBD3 CACNA1H GAS6

6.33e-041952032897_UP
DrugDiltiazem hydrochloride [33286-22-5]; Down 200; 8.8uM; MCF7; HT_HG-U133A

MBD3 MBD1 GAS6

6.33e-041952031532_DN
DrugFelodipine [72509-76-3]; Down 200; 10.4uM; MCF7; HT_HG-U133A

TGM2 CACNA1H MBD1

6.33e-041952033295_DN
DrugFendiline hydrochloride [13636-18-5]; Up 200; 11.4uM; HL60; HG-U133A

GATB MBD3 MBD1

6.33e-041952031573_UP
DrugAcacetin [480-44-4]; Up 200; 14uM; HL60; HT_HG-U133A

SPIB CYP27B1 GAS6

6.33e-041952032189_UP
Drug(+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A

MBD1 GAS6 CELSR3

6.33e-041952034980_DN
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA

GATB GAS6 CELSR3

6.33e-041952031045_UP
DrugGleevec; Up 200; 10uM; MCF7; HG-U133A

MBD3 NAGA CELSR3

6.43e-04196203366_UP
DrugAscorbic acid [50-81-7]; Up 200; 22.4uM; MCF7; HT_HG-U133A

MBD3 CACNA1H PENK

6.43e-041962035407_UP
DrugThiamphenicol [15318-45-3]; Up 200; 11.2uM; HL60; HT_HG-U133A

PENK GAS6 CELSR3

6.43e-041962031867_UP
DrugPrednisolone [50-24-8]; Up 200; 11uM; MCF7; HT_HG-U133A

TGM2 CACNA1H MBD1

6.43e-041962037424_UP
DrugClorsulon [60200-06-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A

TGM2 CACNA1H CELSR3

6.43e-041962032884_UP
DrugIproniazide phosphate [305-33-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A

TGM2 CACNA1H GAS6

6.43e-041962032288_DN
Drugcox-2 inhibitor I; Down 200; 10uM; MCF7; HG-U133A

SPIB MBD1 NAGA

6.43e-04196203253_DN
DrugBuflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A

GATB TGM2 MBD1

6.43e-041962034840_DN
DiseaseCardiac Hypertrophy

RRAD GAS6

1.27e-0382192C1383860
DiseaseCardiomegaly

RRAD GAS6

1.27e-0382192C0018800
Diseasevisual epilepsy (biomarker_via_orthology)

MBD3 MBD1

1.52e-0390192DOID:11832 (biomarker_via_orthology)
Diseasetransient cerebral ischemia (biomarker_via_orthology)

MBD3 MBD1

4.53e-03157192DOID:224 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
MAAPMLRWGCRGRRW

GATB

1

O75879
GGFMRRVGRPEWWMD

PENK

211

P01210
WEQDGGRWLPGHCMA

RRAD

146

P55042
VPGPWGRLCRDWDQM

CYP27B1

246

O15528
MERKRWECPALPQGW

MBD3

1

O95983
MAEDWLDCPALGPGW

MBD1

1

Q9UIS9
PGGRGWASMLACRLW

AQP6

6

Q13520
MGGLWRPGWRCVPFC

COX11

1

Q9Y6N1
PINPRLDGCMRSWNW

GAS6

436

Q14393
KTRCWAQGMDGWRPL

DNAJC13

1006

O75165
GNCRPGRWPVDAWEV

CXorf38

101

Q8TB03
HRMDQQCPRGWWGSP

CELSR3

2021

Q9NYQ7
RAAPGEPGWMGRLWV

CACNA1H

766

O95180
MQDFWRRSCLGGWGP

SLC38A8

321

A6NNN8
RGDMRECVWWVEPGA

SPIB

181

Q01892
CWVESWMTRPDLQPG

TGM2

336

P21980
PGSWCFLRMRWAQPG

PTGIR

166

P43119
RMGPRCAQALWRMPW

ATP6AP1

11

Q15904
MCWGKHWPRPEGRNL

nan

1

Q6ZWC4
GRCWGWGRGMTRICP

nan

66

Q8N9P0
CWMKRPDLPSGFDGW

TGM1

441

P22735
PPMGWLAWERFRCNI

NAGA

26

P17050