Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

2.06e-1843110324GO:0004984
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR8H3 GPR26 OR1S2 OR5AN1 ADGRB2 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 TAAR5 GPRC5C OR1L3 OR1L1 OR10Z1 ADGRL4 ADGRG6 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

5.71e-1788410330GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR8H3 GPR26 OR1S2 OR5AN1 ADGRB2 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 TAAR5 GPRC5C OR1L3 OR1L1 OR10Z1 ADGRL4 ADGRG6 OR1L8 ANTXRL OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

6.91e-13135310331GO:0004888
GeneOntologyMolecularFunctionodorant binding

OR8H3 OR5AN1 OR5K4 OR5K3 OR10Z1 OR5J2 OR5F1

4.26e-061271037GO:0005549
GeneOntologyMolecularFunctioncarbon-sulfur lyase activity

CENPVL2 CENPVL3 CENPVL1

7.11e-05161033GO:0016846
GeneOntologyMolecularFunctionwater channel activity

AQP12A AQP11 AQP12B

8.60e-05171033GO:0015250
GeneOntologyMolecularFunctionwater transmembrane transporter activity

AQP12A AQP11 AQP12B

1.43e-04201033GO:0005372
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

2.29e-194329724GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

1.25e-184659724GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

3.29e-184859724GO:0050907
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 TAAR5 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

3.87e-185479725GO:0007606
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

1.92e-175249724GO:0009593
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

2.06e-165829724GO:0050906
GeneOntologyBiologicalProcesssensory perception

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 TAAR5 GPRC5C OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OTOGL OR51M1 OR10AC1 OR1L6 ALOXE3 OR7A17 MYO15A OR7G3 USH2A OR7A10 OR51B4 OR5F1

6.95e-1610729730GO:0007600
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR8H3 PDE2A GPR26 INPP5A OR1S2 OR5AN1 ADGRB2 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 TAAR5 GPRC5C OR1L3 OR1L1 OR10Z1 ADGRL4 ADGRG6 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 PIK3R5 OR5F1

2.18e-1513959733GO:0007186
GeneOntologyBiologicalProcessdetection of stimulus

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

2.45e-147229724GO:0051606
GeneOntologyCellularComponenteukaryotic translation elongation factor 1 complex

EEF1A1 EEF1A2

1.32e-044992GO:0005853
GeneOntologyCellularComponentendoplasmic reticulum tubular network membrane

ATL3 ATL1

2.20e-045992GO:0098826
DomainOlfact_rcpt

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

3.85e-183939723IPR000725
Domain7tm_1

OR8H3 GPR26 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 TAAR5 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

5.38e-156779725PF00001
DomainG_PROTEIN_RECEP_F1_1

OR8H3 GPR26 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 TAAR5 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

7.04e-156859725PS00237
DomainG_PROTEIN_RECEP_F1_2

OR8H3 GPR26 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 TAAR5 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

8.58e-156919725PS50262
DomainGPCR_Rhodpsn

OR8H3 GPR26 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 TAAR5 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

8.87e-156929725IPR000276
DomainGPCR_Rhodpsn_7TM

OR8H3 GPR26 OR1S2 OR5AN1 OR5K4 OR5K3 OR10H4 OR1C1 TAAR5 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

4.06e-146709724IPR017452
DomainAquaporin_11/12

AQP12A AQP11 AQP12B

1.36e-073973IPR016697
DomainTransl_elong_EF1A_euk/arc

EEF1A1 EEF1A2

2.67e-052972IPR004539
DomainAquaporin_12

AQP12A AQP12B

2.67e-052972IPR023265
DomainMIP

AQP12A AQP11 AQP12B

4.74e-0514973PS00221
DomainMIP

AQP12A AQP11 AQP12B

4.74e-0514973PF00230
DomainMIP

AQP12A AQP11 AQP12B

5.91e-0515973IPR000425
Domain-

AQP12A AQP11 AQP12B

5.91e-05159731.20.1080.10
DomainAquaporin-like

AQP12A AQP11 AQP12B

5.91e-0515973IPR023271
DomainGPS

ADGRB2 ADGRL4 ADGRG6

7.23e-0434973SM00303
DomainZnf-RING_LisH

RNF32 MID2 MID1

7.23e-0434973IPR027370
Domainzf-RING_UBOX

RNF32 MID2 MID1

7.23e-0434973PF13445
DomainTransl_elong_EFTu/EF1A_C

EEF1A1 EEF1A2

7.32e-048972IPR004160
DomainGTP_EFTU_D3

EEF1A1 EEF1A2

7.32e-048972PF03143
DomainGPS

ADGRB2 ADGRL4 ADGRG6

7.88e-0435973PF01825
DomainGPS

ADGRB2 ADGRL4 ADGRG6

8.56e-0436973PS50221
DomainGPS

ADGRB2 ADGRL4 ADGRG6

9.28e-0437973IPR000203
DomainG_TR_CS

EEF1A1 EEF1A2

9.39e-049972IPR031157
DomainTransl_elong_EF1A/Init_IF2_C

EEF1A1 EEF1A2

1.17e-0310972IPR009001
DomainGBP_C

ATL3 ATL1

1.17e-0310972PF02841
DomainEGF_3

CUBN SSPOP ADGRL4 SCUBE1 ADAM33 GP2

1.42e-03235976PS50026
DomainGAIN_dom_N

ADGRB2 ADGRL4

1.42e-0311972IPR032471
DomainG_GB1_RHD3_dom

ATL3 ATL1

1.42e-0311972IPR030386
DomainGuanylate-bd_C

ATL3 ATL1

1.42e-0311972IPR003191
DomainGBP

ATL3 ATL1

1.42e-0311972PF02263
DomainGAIN

ADGRB2 ADGRL4

1.42e-0311972PF16489
DomainGuanylate-bd_N

ATL3 ATL1

1.42e-0311972IPR015894
DomainG_GB1_RHD3

ATL3 ATL1

1.42e-0311972PS51715
DomainEGF_3

CUBN SCUBE1

1.70e-0312972PF12947
DomainCOS_domain

MID2 MID1

1.70e-0312972IPR017903
DomainEGF_dom

CUBN SCUBE1

1.70e-0312972IPR024731
DomainCOS

MID2 MID1

1.70e-0312972PS51262
DomainCRAL_TRIO_2

MCF2 NF1

1.70e-0312972PF13716
DomainG_TR_1

EEF1A1 EEF1A2

2.01e-0313972PS00301
DomainCUB

CUBN ADGRG6 SCUBE1

2.10e-0349973PF00431
DomainEGF_1

CUBN SSPOP SCUBE1 ADAM33 USH2A GP2

2.14e-03255976PS00022
DomainG_PROTEIN_RECEP_F2_2

ADGRB2 ADGRL4 ADGRG6

2.23e-0350973PS00650
Domain7tm_2

ADGRB2 ADGRL4 ADGRG6

2.23e-0350973PF00002
DomainCUB

CUBN ADGRG6 SCUBE1

2.23e-0350973SM00042
Domain-

CUBN ADGRG6 SCUBE1

2.50e-03529732.60.120.290
DomainEGF_2

CUBN SSPOP ADGRL4 SCUBE1 ADAM33 GP2

2.59e-03265976PS01186
DomainCUB

CUBN ADGRG6 SCUBE1

2.64e-0353973PS01180
DomainBbox_C

MID2 MID1

2.68e-0315972IPR003649
DomainBBC

MID2 MID1

2.68e-0315972SM00502
DomainCUB_dom

CUBN ADGRG6 SCUBE1

3.24e-0357973IPR000859
DomainGPCR_2_secretin-like

ADGRB2 ADGRL4 ADGRG6

3.75e-0360973IPR000832
DomainGPCR_2-like

ADGRB2 ADGRL4 ADGRG6

3.75e-0360973IPR017981
DomainEFTu-like_2

EEF1A1 EEF1A2

3.87e-0318972IPR004161
DomainGTP_EFTU_D2

EEF1A1 EEF1A2

3.87e-0318972PF03144
DomainG_TR_2

EEF1A1 EEF1A2

3.87e-0318972PS51722
DomainG_PROTEIN_RECEP_F2_4

ADGRB2 ADGRL4 ADGRG6

3.93e-0361973PS50261
DomainZF_RING_1

MKRN4P RNF32 MID2 BFAR MID1 PRKN

4.11e-03291976PS00518
DomainTF_GTP-bd_dom

EEF1A1 EEF1A2

4.31e-0319972IPR000795
DomainPDEase

PDE2A PDE8B

4.31e-0319972IPR023088
DomainZF_RING_2

MKRN4P RNF32 MID2 BFAR MID1 PRKN

4.61e-03298976PS50089
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

1.36e-184177724M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR1C1 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OTOGL OR51M1 OR10AC1 OR1L6 OR7A17 MYO15A OR7G3 OR7A10 OR51B4 OR5F1

1.65e-166367726M41834
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR8H3 OR1S2 OR5AN1 OR10H4 OR1C1 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR10H2 OR51M1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4 OR5F1

1.41e-143897720M14091
PathwayWP_GPCRS_ODORANT

GPR26 OR10H4 TAAR5 ADGRG6 OR5J2 OR10H3 OR7A17 OR7A10

2.17e-06157778MM15872
PathwayREACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS

AQP12A AQP11 AQP12B

4.31e-0513773MM15095
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4

5.56e-193401041911802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4

6.56e-193431041932295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4

7.72e-193461041914611657
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR8H3 OR1S2 OR5AN1 OR1F12P OR5K4 OR5K3 OR10H4 OR10Z1 OR1L8 OR5J2 OR10H3 OR51Q1 OR51M1 OR1L6 OR7A17 OR7G3 OR7A10 OR51B4

1.31e-173401041811875048
Pubmed

The human olfactory receptor gene family.

OR8H3 OR1S2 OR5AN1 OR1F12P OR10H4 OR1C1 OR1L3 OR1L1 OR10Z1 OR1L8 OR5J2 OR10H3 OR10H2 OR51M1 OR10AC1 OR1L6 OR7A17 OR7G3 OR7A10 OR5F1

1.85e-165411042014983052
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR1S2 OR10H4 OR1C1 OR1L8 OR10H2 OR1L6 OR7A17 OR7G3 OR7A10 OR5F1

1.24e-092191041012213199
Pubmed

Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow.

CENPVL2 CENPVL3 CENPVL1

5.16e-076104327250503
Pubmed

Mouse translation elongation factor eEF1A-2 interacts with Prdx-I to protect cells against apoptotic death induced by oxidative stress.

EEF1A1 EEF1A2 PRDX1

5.16e-076104316888816
Pubmed

Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.

OR8H3 OR51Q1 OR7A17 OR7A10

1.26e-0627104432061665
Pubmed

Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2.

EEF1A1 MYO15A USH2A

2.15e-069104323144817
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR5AN1 OR10AC1 OR7A17 OR7G3 OR7A10

2.97e-0674104515081110
Pubmed

New insights on the interaction between the isoforms 1 and 2 of human translation elongation factor 1A.

EEF1A1 EEF1A2

8.86e-062104226212729
Pubmed

Mid1/Mid2 expression in craniofacial development and a literature review of X-linked opitz syndrome.

MID2 MID1

8.86e-062104226788540
Pubmed

In silico study of human aquaporin AQP11 and AQP12 channels.

AQP12A AQP11

8.86e-062104223359558
Pubmed

The expression levels of the translational factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade.

EEF1A1 EEF1A2

8.86e-062104217825975
Pubmed

Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression.

EEF1A1 EEF1A2

8.86e-062104222095224
Pubmed

eEF1A demonstrates paralog specific effects on HIV-1 reverse transcription efficiency.

EEF1A1 EEF1A2

8.86e-062104230782564
Pubmed

Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach.

EEF1A1 EEF1A2

8.86e-062104238220433
Pubmed

Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation.

EEF1A1 EEF1A2

8.86e-062104219636410
Pubmed

Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells.

AQP12A AQP12B

8.86e-062104215809071
Pubmed

Analysis of the Expression and Subcellular Distribution of eEF1A1 and eEF1A2 mRNAs during Neurodevelopment.

EEF1A1 EEF1A2

8.86e-062104235741005
Pubmed

Pancreas-specific aquaporin 12 null mice showed increased susceptibility to caerulein-induced acute pancreatitis.

AQP12A AQP12B

8.86e-062104219726746
Pubmed

Genetic analysis of the aquaporin water channels AQP12A and AQP12B in patients with chronic pancreatitis.

AQP12A AQP12B

8.86e-062104236167651
Pubmed

Tissue and zonal-specific expression of an olfactory receptor transgene.

OR10H4 OR10H3

8.86e-06210429412503
Pubmed

The role of translation elongation factor eEF1 subunits in neurodevelopmental disorders.

EEF1A1 EEF1A2

8.86e-062104230370994
Pubmed

The Effects of Indian Hedgehog Deletion on Mesenchyme Cells: Inducing Intermediate Cartilage Scaffold Ossification to Cause Growth Plate and Phalange Joint Absence, Short Limb, and Dwarfish Phenotypes.

PRDX1 IHH

8.86e-062104230032718
Pubmed

Cloning of human and mouse brain cDNAs coding for S1, the second member of the mammalian elongation factor-1 alpha gene family: analysis of a possible evolutionary pathway.

EEF1A1 EEF1A2

8.86e-06210427945283
Pubmed

mTORC2 regulates auditory hair cell structure and function.

RICTOR MYO15A

8.86e-062104237694145
Pubmed

Dimethylation of eEF1A at Lysine 55 Plays a Key Role in the Regulation of eEF1A2 on Malignant Cell Functions of Acute Myeloid Leukemia.

EEF1A1 EEF1A2

8.86e-062104232347192
Pubmed

Aquaporins 8 and 9 as Possible Markers for Adult Murine Lacrimal Gland Cells.

AQP12A AQP11 AQP12B

1.15e-0515104334540996
Pubmed

Olfactory receptors and signalling elements in the Grueneberg ganglion.

OR8H3 OR7A17 OR7A10

1.71e-0517104316805845
Pubmed

Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance.

AQP12A AQP11 AQP12B

1.71e-0517104326847765
Pubmed

Expression patterns of the aquaporin gene family during renal development: influence of genetic variability.

AQP12A AQP11 AQP12B

2.43e-0519104319367412
Pubmed

MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.

MID2 MID1

2.65e-053104211806752
Pubmed

Interaction of elongation factor 1-alpha with leucine-rich repeat kinase 2 impairs kinase activity and microtubule bundling in vitro.

EEF1A1 EEF1A2

2.65e-053104219559761
Pubmed

Human atlastin GTPases mediate differentiated fusion of endoplasmic reticulum membranes.

ATL3 ATL1

2.65e-053104225773277
Pubmed

The nucleocapsid protein of severe acute respiratory syndrome coronavirus inhibits cell cytokinesis and proliferation by interacting with translation elongation factor 1alpha.

EEF1A1 EEF1A2

2.65e-053104218448518
Pubmed

Endogenous epitope tagging of eEF1A2 in mice reveals early embryonic expression of eEF1A2 and subcellular compartmentalisation of neuronal eEF1A1 and eEF1A2.

EEF1A1 EEF1A2

2.65e-053104237429391
Pubmed

Mammalian knock out cells reveal prominent roles for atlastin GTPases in ER network morphology.

ATL3 ATL1

2.65e-053104227669642
Pubmed

Identification of reliable reference genes for qRT-PCR studies of the developing mouse mammary gland.

PRDX1 CTBP1

2.65e-053104227752147
Pubmed

Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

OR1C1 OR7A17 OR7A10

5.02e-052410439119360
Pubmed

Characterization of elongation factor-1A (eEF1A-1) and eEF1A-2/S1 protein expression in normal and wasted mice.

EEF1A1 EEF1A2

5.29e-054104211294870
Pubmed

Identification of regulators of chaperone-mediated autophagy.

EEF1A1 EEF1A2

5.29e-054104220797626
Pubmed

MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation.

MID2 MID1

5.29e-054104211685209
Pubmed

Immuno-characterization of the switch of peptide elongation factors eEF1A-1/EF-1alpha and eEF1A-2/S1 in the central nervous system during mouse development.

EEF1A1 EEF1A2

5.29e-054104215013623
Pubmed

The human Y-encoded testis-specific protein interacts functionally with eukaryotic translation elongation factor eEF1A, a putative oncoprotein.

EEF1A1 EEF1A2

8.80e-055104218649364
Pubmed

Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network.

ATL3 ATL1

8.80e-055104227619977
Pubmed

Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA.

EEF1A1 EEF1A2

8.80e-05510428626763
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRB2 ADGRL4 ADGRG6

8.97e-0529104315203201
Pubmed

Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding.

MID2 MID1

1.32e-046104216434393
Pubmed

Visualizing an olfactory sensory map.

OR7A17 OR7A10

1.32e-04610428929536
Pubmed

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.

ADGRB2 ADGRL4 ADGRG6

1.33e-0433104325713288
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CAMSAP3 ATL3 RICTOR UPF2 WDCP DSTYK MID1 TNFAIP2 PARP12

1.49e-04650104938777146
Pubmed

A class of dynamin-like GTPases involved in the generation of the tubular ER network.

ATL3 ATL1

1.84e-047104219665976
Pubmed

Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation.

ATL3 ATL1

1.84e-047104223969831
Pubmed

Disruption of Scube2 Impairs Endochondral Bone Formation.

SCUBE1 IHH

1.84e-047104225639508
Pubmed

Notch pathway activation targets AML-initiating cell homeostasis and differentiation.

TET2 EEF1A1

1.84e-047104223359070
Pubmed

Bridging expressed sequence alignments through targeted cDNA sequencing.

SCUBE1 USP51

2.45e-048104215028280
Pubmed

[Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two-hybrid system].

EEF1A1 PRDX1

2.45e-048104216583711
Pubmed

YB-1 is important for an early stage embryonic development: neural tube formation and cell proliferation.

EEF1A1 EEF1A2

2.45e-048104217082189
Pubmed

The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells.

TNFAIP2 GP2

3.14e-049104222706340
Pubmed

Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.

RICTOR NF1

3.14e-049104227340174
Pubmed

The E3 Ubiquitin Ligase SYVN1 Ubiquitinates Atlastins to Remodel the Endoplasmic Reticulum Network.

ATL3 ATL1

3.14e-049104232916628
Pubmed

SEREX identification of new tumour-associated antigens in cutaneous T-cell lymphoma.

INPP5A EEF1A1

3.14e-049104214996095
Pubmed

Identification of the ligands of protein interaction domains through a functional approach.

CUBN EEF1A1

3.14e-049104217124247
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

EMC9 SCUBE1 SNTG1 PRKN USH2A

3.39e-04199104523382691
Pubmed

Multiple roles for neurofibromin in skeletal development and growth.

NF1 IHH

4.79e-0411104217317783
Pubmed

Identification of ligands for olfactory receptors by functional expression of a receptor library.

OR7A17 OR7A10

5.73e-041210429875846
Pubmed

The Opitz syndrome gene product MID1 assembles a microtubule-associated ribonucleoprotein complex.

EEF1A1 MID1

5.73e-0412104218172692
Pubmed

Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway.

EEF1A1 EEF1A2

6.76e-0413104229285303
Pubmed

Evolution of odorant receptors expressed in mammalian testes.

OR7A17 OR7A10

6.76e-0413104211014824
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

BRSK2 EEF1A1 EEF1A2 NF1

6.80e-04132104416944949
Pubmed

Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb.

OR7A17 OR7A10

7.87e-041410427528109
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

CAMSAP3 MED14 SLC39A10 ZYX EEF1A1 PRDX1 TNFAIP2

9.05e-04513104725798074
Pubmed

Assignment of human elongation factor 1alpha genes: EEF1A maps to chromosome 6q14 and EEF1A2 to 20q13.3.

EEF1A1 EEF1A2

9.07e-041510428812466
Pubmed

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

OR51M1 OR51B4

9.07e-0415104211121057
Pubmed

Embryonic Lethality Due to Arrested Cardiac Development in Psip1/Hdgfrp2 Double-Deficient Mice.

ITGA9 PIK3R5

9.07e-0415104226367869
Pubmed

An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression.

RNF32 IHH

9.07e-0415104215841179
Pubmed

Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.

OR51M1 OR51B4

9.07e-0415104210220430
Pubmed

Cyclin B1/Cdk1 binds and phosphorylates Filamin A and regulates its ability to cross-link actin.

SCUBE1 PRDX1

1.03e-0316104217408621
Pubmed

Zfp423/OAZ participates in a developmental switch during olfactory neurogenesis.

OR10H4 OR10H3

1.03e-0316104217521568
Pubmed

PML Recruits TET2 to Regulate DNA Modification and Cell Proliferation in Response to Chemotherapeutic Agent.

TET2 EEF1A1 PRDX1

1.08e-0367104329735542
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TET2 CAMSAP3 BRSK2 RICTOR ZYX EEF1A1 EEF1A2 NF1 DSTYK

1.13e-03861104936931259
Pubmed

Chromosomal location-dependent nonstochastic onset of odor receptor expression.

OR7A17 OR7A10

1.17e-0317104220668191
Pubmed

Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm.

EEF1A1 EEF1A2

1.31e-0318104212426392
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADGRB2 CUBN SSPOP

1.50e-0375104320637190
Pubmed

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.

CUBN PRDX1

1.62e-0320104223824729
Pubmed

LUCAT1 promotes colorectal cancer tumorigenesis by targeting the ribosomal protein L40-MDM2-p53 pathway through binding with UBA52.

EEF1A1 PRDX1

1.62e-0320104230690837
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

RHBDF1 DOCK9 RICTOR SLC39A10 NF1 NOX1 STXBP6

1.64e-03569104730639242
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

SGSM1 CAMSAP3 SSPOP EEF1A1 EEF1A2 PRDX1 TUBE1 OR7A10

1.68e-03736104829676528
Pubmed

The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division.

MID2 MID1

1.97e-0322104226748699
Pubmed

The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.

OR7A17 OR7A10

2.15e-0323104210706615
Pubmed

Nef interaction with actin compromises human podocyte actin cytoskeletal integrity.

ZYX EEF1A1

2.15e-0323104222721673
Pubmed

De-regulated STAT5A/miR-202-5p/USP15/Caspase-6 regulatory axis suppresses CML cell apoptosis and contributes to Imatinib resistance.

EEF1A1 PRDX1

2.34e-0324104231952546
Pubmed

Interaction of Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and Vav3 in the Receptor Activator of Nuclear Factor κB (RANK) Signaling Complex Enhances Osteoclastogenesis.

EEF1A1 NF1

2.34e-0324104227507811
Pubmed

Regulation of MAGE-A3/6 by the CRL4-DCAF12 ubiquitin ligase and nutrient availability.

EEF1A1 EEF1A2 PRDX1

2.45e-0389104331267705
Pubmed

Overview of PDEs and their regulation.

PDE2A PDE8B

2.54e-0325104217307970
Pubmed

Expression of members of the putative olfactory receptor gene family in mammalian germ cells.

OR5J2 OR7A17

2.54e-032510421370859
Pubmed

RBBP8/CtIP suppresses P21 expression by interacting with CtBP and BRCA1 in gastric cancer.

EEF1A1 CTBP1

2.54e-0325104231636387
Pubmed

Genome-wide association studies and heritability estimates of body mass index related phenotypes in Bangladeshi adults.

PELI2 STXBP6

2.96e-0327104225133637
Cytoband9q33.2

OR1L3 OR1L1 OR1L8 OR1L6

1.92e-063910449q33.2
Cytoband19p13.12

OR10H4 OR7A17 OR7A10

2.05e-0450104319p13.12
CytobandEnsembl 112 genes in cytogenetic band chrXp11

MKRN4P MED14 CENPVL2 CENPVL3 USP51 CENPVL1

2.27e-043771046chrXp11
CytobandXp11.22

CENPVL2 CENPVL3 CENPVL1

2.58e-04541043Xp11.22
CytobandEnsembl 112 genes in cytogenetic band chr9q33

OR1L3 OR1L1 OR1L8 OR1L6

2.85e-041381044chr9q33
Cytoband11q12.1

OR8H3 OR1S2 OR5AN1 OR5F1

5.10e-04161104411q12.1
Cytoband3q12.1

OR5K4 OR5K3

1.04e-032110423q12.1
CytobandEnsembl 112 genes in cytogenetic band chr11q12

OR8H3 OR1S2 OR5AN1 OR5J2 OR5F1

1.17e-033451045chr11q12
CytobandEnsembl 112 genes in cytogenetic band chr19p13

CAMSAP3 OR10H4 OR10H3 OR10H2 OR7A17 OR7G3 OR7A10

2.30e-037971047chr19p13
GeneFamilyOlfactory receptors, family 1

OR1S2 OR1F12P OR1C1 OR1L3 OR1L1 OR1L8 OR1L6

2.41e-1040747147
GeneFamilyOlfactory receptors, family 10

OR10H4 OR10Z1 OR10H3 OR10H2 OR10AC1

7.37e-0666745157
GeneFamilyAquaporins

AQP12A AQP11 AQP12B

2.32e-0514743305
GeneFamilyOlfactory receptors, family 5

OR5AN1 OR5K4 OR5K3 OR5J2 OR5F1

9.56e-05112745152
GeneFamilyOlfactory receptors, family 51

OR51Q1 OR51M1 OR51B4

7.73e-0444743164
GeneFamilyPhosphodiesterases

PDE2A PDE8B

4.30e-0324742681
GeneFamilyRing finger proteins

MKRN4P RNF32 MID2 BFAR MID1

5.38e-0327574558
ToppCellTuft-tuft-1|World / Class top

MID2 AQP11 ADGRB2 MED14 CUBN ALOXE3

2.63e-0616810368ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A DOCK9 ITGA9 EEF1A1 ADGRL4 PRDX1

3.91e-06180103616728b9a1c52097e3a460534be71a476ecc54f0f
Diseasehereditary spastic paraplegia 3A (implicated_via_orthology)

ATL3 ATL1

3.07e-053952DOID:0110791 (implicated_via_orthology)
Diseasedevelopmental and epileptic encephalopathy 33 (implicated_via_orthology)

EEF1A1 EEF1A2

3.07e-053952DOID:0080463 (implicated_via_orthology)
DiseaseOpitz GBBB syndrome (implicated_via_orthology)

MID2 MID1

1.53e-046952DOID:0080697 (implicated_via_orthology)
Diseasecolon cancer (is_implicated_in)

CASP7 RICTOR PIK3R5

2.14e-0436953DOID:219 (is_implicated_in)
DiseaseHereditary Sensory Autonomic Neuropathy, Type 1

ATL3 ATL1

2.84e-048952C0020071
Diseasecognitive inhibition measurement

ADGRG6 SNTG1 USH2A

5.68e-0450953EFO_0007969
Diseaseidiopathic scoliosis (implicated_via_orthology)

SSPOP ADGRG6

1.20e-0316952DOID:0060250 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

PDE2A MED14 CASP7 CUBN ITGA9 NF1 OTOGL WDCP SLC28A1 ADAM33

2.41e-0310749510C0006142
DiseaseCarcinoma of lung

RICTOR PRKN

2.48e-0323952C0684249
Diseasefasting blood glucose measurement, HOMA-B, fasting blood insulin measurement

OR1L3 OR1L1

2.93e-0325952EFO_0004465, EFO_0004466, EFO_0004469

Protein segments in the cluster

PeptideGeneStartEntry
ETHTSCRCNHLTHFA

ADGRL4

396

Q9HBW9
AAHTRCQCQHLSTFA

ADGRB2

901

O60241
ALVEAACAFCFHLTL

AQP12A

151

Q8IXF9
LDTFCDLSHASCHQV

ANTXRL

446

A6NF34
LLFHSDCVTLHCGLN

CTBP1

226

Q13363
SETVCLCNHFTHFGV

ADGRG6

831

Q86SQ4
AFQELQRCLTACHSH

ADAM33

646

Q9BZ11
ALHSFCSRCGVQSFH

CENPVL1

196

A0A0U1RR11
ALVEAACAFCFHLTL

AQP12B

151

A6NM10
NKFIIHNALSHCCLA

CAMSAP3

1121

Q9P1Y5
EHRFGILSNCNHTFC

MKRN4P

331

Q13434
HLTHFSCTDDVFACF

RCBTB2

346

O95199
HTAIHIIAHLFNFDC

NOX1

111

Q9Y5S8
LTFCGSHEIQHFLCH

OR10H2

166

O60403
LHFCSDNVIHHFFCD

OR1F12P

166

Q8NHA8
FFCDITALLHLACTR

OR10AC1

181

Q8NH08
KFQSHLGHEDLFSCC

MFSD4A

281

Q8N468
CFPQATDHTFLQKCH

MYO15A

1666

Q9UKN7
LCCQTPTDLHAHFLA

NLRP11

361

P59045
NTHFLCTHLLCEAFA

ALOXE3

406

Q9BYJ1
FFRQIISALDFCHSH

BRSK2

121

Q8IWQ3
ISALDFCHSHSICHR

BRSK2

126

Q8IWQ3
FHALSFLLSFVVLCC

GPR26

176

Q8NDV2
CAFDLVNIHLFHDAS

INPP5A

176

Q14642
AHAACFTQSFIHSLA

OR51B4

91

Q9Y5P0
CGSRALLHTFCLHQD

OR51B4

166

Q9Y5P0
CGSVVLSHSFCLHQE

OR51M1

181

Q9H341
CHSHLLSRSYCLHQD

OR51Q1

171

Q8NH59
IFALFISCMCHDLDH

PDE2A

686

O00408
RACNSVFTALDHCHE

PDE8B

266

O95263
LVFLHCEIHLCDSLN

GP2

456

P55259
LTFCGSHQINHFFCD

OR5K3

166

A6NET4
LSFCRLNAVSHFFCD

OR5J2

166

Q8NH18
QLHFCGSNVIRHFFC

OR5AN1

166

Q8NGI8
CLYSEVSHLLSHCTF

RICTOR

1651

Q6R327
FFRDIKCSHNHTCLS

DSTYK

51

Q6XUX3
LHFCDSNIIHHFFCD

OR8H3

166

Q8N146
CGNSECLHIFVDLHS

MED14

446

O60244
CQVIGASVDSHFCHL

PRDX1

71

Q06830
HLTFCGSNVIHHFLC

OR10H3

166

O60404
HHFFCHVLSLLKLAC

OR10H4

176

Q8NGA5
LIFCASNVIHHFFCD

OR1L1

216

Q8NH94
FCDHNTLPHFFCDLA

OR1S2

181

Q8NGQ3
LSFCSSHEIQHFFCD

OR10Z1

166

Q8NGY1
LCSESASTFHSHCLN

PARP12

331

Q9H0J9
LFAICFSCLAAHVFA

GPRC5C

126

Q9NQ84
CLNVTTCFSFHGKHV

ITGA9

491

Q13797
TFLAFDLEHHINCST

CUBN

1321

O60494
IIFHCHRAVLAACSN

KLHL23

46

Q8NBE8
HIHSCFTNISCFLLP

ATL1

256

Q8WXF7
TLNCGHSFCRHCLAL

BFAR

46

Q9NZS9
HHLLLTFFHVSCDNS

DOCK9

726

Q9BZ29
ATFLAHNDSHTFFCC

GLYCTK

481

Q8IVS8
ALHSFCSRCGVQSFH

CENPVL2

196

P0DPI3
IDCHTAHIACKFAEL

EEF1A2

361

Q05639
LDCHTAHIACKFAEL

EEF1A1

361

P68104
ALHSFCSRCGVQSFH

CENPVL3

196

A0A0U1RRI6
FHSLRQKLSHCISCA

IL26

111

Q9NPH9
NHIHSCFSDVTCFLL

ATL3

251

Q6DD88
HTNAACFACILLSHG

CASP7

131

P55210
HNDIFLSSLENCAHA

MCF2

556

P10911
LCLTDCVPLFHSHLA

EMC9

41

Q9Y3B6
YCSAFHSNCHSAISL

HHIPL2

136

Q6UWX4
VCLDHIFGHNCSLSC

EGFEM1P

11

Q0D2K5
LDHCHVTFVTLKCDS

SCUBE1

516

Q8IWY4
LICLLTFIFHHCNHC

SLC39A10

11

Q9ULF5
SCFAAVADHHLAQLA

IHH

346

Q14623
YHHCSSFCLHSCISL

OTOGL

751

Q3ZCN5
LSFCASNIIHHFFCD

OR1C1

166

Q15619
LSFCDSNVIHHFFCD

OR5F1

166

O95221
ISDVNCAVHLCSLFH

UPF2

216

Q9HAU5
LTFCTSNVIHHFFCD

OR1L3

166

Q8NH93
CASHIIKHFFCDTQP

OR1L6

206

Q8NGR2
HCVLLVAFSCSFPHL

OR1L8

141

Q8NGR8
RLTFCDSNVIHHFLC

OR1L8

166

Q8NGR8
SIFHLCFISIDRHCA

TAAR5

121

O14804
HQFLLSACTHVGCTN

USH2A

2116

O75445
CTTHSQRHAFAEAAC

SSPOP

746

A2VEC9
FQCNSRHVICLDCFH

PRKN

251

O60260
ANSLFLEVDHFSCCN

SYT16

81

Q17RD7
NLFAVLHCIHSFFAA

SNTG1

471

Q9NSN8
LHCIHSFFAAKVACL

SNTG1

476

Q9NSN8
HFFCEINQVVHLACS

OR7A10

176

O76100
HFFCELAHILKLACS

OR7G3

176

Q8NG95
HAFHAACPFCATQLV

PELI2

391

Q9HAT8
FLHAGILHCLVSICF

RHBDF1

661

Q96CC6
LLSCSHVFHKACLQA

RNF32

141

Q9H0A6
SCSHVFHHACLLALE

RNF32

321

Q9H0A6
AFTLFATHFLELCHI

MSH4

786

O15457
HFFCELNQVIHLACS

OR7A17

176

O14581
HCVEHDAFIFALCQD

NUP160

291

Q12769
LTFCRSNKIHHFFCD

OR5K4

166

A6NMS3
DASSIVFLCDLHIHF

B4GALNT4

906

Q76KP1
AVCSFLFHSALLHFQ

AQP11

171

Q8NBQ7
AKCFCNSSHLIQHLR

ZNF572

166

Q7Z3I7
THMNRLHSCLSCVFF

USP51

241

Q70EK9
ASEKCTFFQILHHTC

STXBP6

116

Q8NFX7
HFAAHLAAVAQFELC

TNFAIP2

256

Q03169
LLLHAFQATFGAHCD

PIK3R5

196

Q8WYR1
SAEHCDCLQCFFIIH

TUBE1

131

Q9UJT0
AHSLCFNCAHRILVS

MID1

26

O15344
FNCAHRILVSHCATN

MID1

31

O15344
HSLCTCSQLHFSEET

NF1

2131

P21359
HIISFCAAVEACVLH

SGSM1

41

Q2NKQ1
CVFVALLFACSKHHC

SLC28A1

186

O00337
LGQLFHIACFTCHQC

ZYX

401

Q15942
AHSLCFSCAHRILVS

MID2

46

Q9UJV3
LHRCSSCLVFDVDSH

WDCP

191

Q9H6R7
VTACLDFCAHAHRDL

TET2

1371

Q6N021
CQTAHSFSLHRLPCF

WDR87

301

Q6ZQQ6