Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainRIH_assoc-dom

RYR1 ITPR2 ITPR3

8.46e-0661423IPR013662
DomainIns145_P3_rec

RYR1 ITPR2 ITPR3

8.46e-0661423PF08709
DomainRIH_assoc

RYR1 ITPR2 ITPR3

8.46e-0661423PF08454
DomainRIH_dom

RYR1 ITPR2 ITPR3

8.46e-0661423IPR000699
DomainIns145_P3_rcpt

RYR1 ITPR2 ITPR3

8.46e-0661423IPR014821
DomainRyanodine_recept-rel

RYR1 ITPR2 ITPR3

8.46e-0661423IPR015925
Domain-

RYR1 ITPR2 ITPR3

8.46e-06614231.25.10.30
DomainRYDR_ITPR

RYR1 ITPR2 ITPR3

8.46e-0661423PF01365
DomainMIR

RYR1 ITPR2 ITPR3

4.97e-05101423PF02815
DomainMIR_motif

RYR1 ITPR2 ITPR3

4.97e-05101423IPR016093
DomainMIR

RYR1 ITPR2 ITPR3

4.97e-05101423PS50919
DomainMIR

RYR1 ITPR2 ITPR3

4.97e-05101423SM00472
DomainFAO_M

PDPR SARDH

1.71e-0431422PF16350
DomainInsP3_rcpt-bd

ITPR2 ITPR3

1.71e-0431422IPR000493
DomainFAO_M

PDPR SARDH

1.71e-0431422IPR032503
DomainPHD_4

KDM2B KDM2A

1.71e-0431422PF16866
DomainARM-type_fold

MYBBP1A INTS7 SARM1 IPO4 ITPR2 CLTC TAF2 HEATR5B AP3D1 ARMC8

2.72e-0433914210IPR016024
Domain-

PDPR SARDH

3.41e-04414222.40.30.110
DomainGcvT/YgfZ_C

PDPR SARDH

3.41e-0441422IPR029043
DomainGCV_T

PDPR SARDH

5.65e-0451422PF01571
Domain-

PDPR SARDH

5.65e-04514223.30.1360.120
DomainTrmE/GcvT_dom1

PDPR SARDH

5.65e-0451422IPR027266
DomainYD

NID2 TENM2

5.65e-0451422IPR006530
DomainGCV_T_C

PDPR SARDH

5.65e-0451422IPR013977
DomainGCV_T_C

PDPR SARDH

5.65e-0451422PF08669
DomainGCV_T_N

PDPR SARDH

5.65e-0451422IPR006222
DomainQuino_amine_DH_bsu

NID2 LRRK1 TENM2

5.96e-04221423IPR011044
DomainFHA

STARD9 AFDN KIF13A

1.23e-03281423SM00240
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ANKRD13D EPPK1 ITPRIPL2 RHBDF1 SZT2 UBE3B LAMA5 AMBRA1 KTI12 PARVB LRRK1 ATG2A EDC4 RYR1 ITPR2 ITPR3 PTPRF CELSR2 UCKL1 ARHGAP44 AP3D1 NOTCH1

2.50e-0911051502235748872
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MYBBP1A UACA IPO4 OR4D2 ITPR3 ANAPC1 ZC3H4 CLTC AP3D1

2.58e-07202150933005030
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

RHBDF1 UACA INTS7 LAMA5 URB2 EDC4 IPO4 ECT2 MAP7D1 NFATC2 EHMT2 ANAPC1 SLC25A13 RPF2 KDM2B AFDN TAF2 PARD3 HEATR5B MTCH2 TARBP2 ARMC8

5.10e-0714971502231527615
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 ITPR2 ITPR3

1.56e-066150323463619
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 ITPR2 ITPR3

1.56e-066150325966694
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 ITPR2 ITPR3

1.56e-066150320519450
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 ITPR2 ITPR3

1.56e-066150316844763
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 ITPR2 ITPR3

2.72e-067150311860456
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR1 ITPR2 ITPR3

4.33e-068150319033399
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

ANKRD13D LAMA5 RYR1 ITPR3 RPF2 ARNT2 SDK1 MNT

4.48e-06214150822199357
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MYBBP1A UACA EDC4 IPO4 TENM2 MAP7D1 CELSR2 EHMT2 ANAPC1 ZC3H4 ARHGAP44 CLTC AFDN TACC3 PARD3 ARMC8

4.54e-069631501628671696
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

PABIR1 SZT2 TTLL5 LRRC32 TENM2 RYR1 CAPN13 ESYT3 MYO15B NFATC2 PRCP TMEM209

5.38e-065521501210737800
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NID2 UACA WEE1 AMBRA1 MAP7D1 MLH3 EHMT2 ANAPC1 ZC3H4 UCKL1 SLC25A13 MAIP1 CEP295 TAF2 PARD3 TARBP2 PML

7.06e-0611161501731753913
Pubmed

Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells.

VPS33B CLTC AP3D1

1.68e-0512150321411634
Pubmed

Genetic studies of the Fv-1 locus of mice: linkage with Gpd-1 in recombinant inbred lines.

H6PD TYRP1

1.85e-0521502196096
Pubmed

Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin.

ITPR2 ITPR3

1.85e-05215029065779
Pubmed

Expression of xenotropic murine leukemia viruses as cell-surface gp70 in genetic crosses between strains DBA/2 and C57BL/6.

H6PD TYRP1

1.85e-0521502221612
Pubmed

Combined expression levels of KDM2A and KDM2B correlate with nucleolar size and prognosis in primary breast carcinomas.

KDM2B KDM2A

1.85e-052150232901907
Pubmed

Abnormal overexpression of G9a in melanoma cells promotes cancer progression via upregulation of the Notch1 signaling pathway.

EHMT2 NOTCH1

1.85e-052150232015216
Pubmed

Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

1.85e-05215028081734
Pubmed

Genetic mapping of the Fv-1 lcous of the mouse.

H6PD TYRP1

1.85e-05215024349512
Pubmed

H3K9 methyltransferase EHMT2/G9a controls ERVK-driven noncanonical imprinted genes.

EHMT2 HPRT1

1.85e-052150234519223
Pubmed

Map position of dysgenetic lens (dyl) locus on chromosome 4 in the mouse.

TYRP1 FOXE3

1.85e-05215023569904
Pubmed

The position of autosomal glucose-6-phosphate dehydrogenase on linkage group 8 of the mouse.

H6PD TYRP1

1.85e-05215025496133
Pubmed

Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.

ITPR2 ITPR3

1.85e-052150215632133
Pubmed

FTD-associated behavioural and transcriptomic abnormalities in 'humanized' progranulin-deficient mice: A novel model for progranulin-associated FTD.

GRN HPRT1

1.85e-052150237105261
Pubmed

Tissue and zonal-specific expression of an olfactory receptor transgene.

OR10H4 OR10H3

1.85e-05215029412503
Pubmed

Expression of IP3 receptor isoforms at the nodes of Ranvier in rat sciatic nerve.

ITPR2 ITPR3

1.85e-052150217496801
Pubmed

Human progranulin-expressing mice as a novel tool for the development of progranulin-modulating therapeutics.

GRN HPRT1

1.85e-052150233636385
Pubmed

Linkage analysis of the murine interferon-alpha locus on chromosome 4.

H6PD TYRP1

1.85e-05215026330270
Pubmed

EHMT2 suppresses the variation of transcriptional switches in the mouse embryo.

EHMT2 HPRT1

1.85e-052150234793451
Pubmed

Biological Functions of the KDM2 Family of Histone Demethylases.

KDM2B KDM2A

1.85e-052150237751135
Pubmed

Nuclear factor of activated T-cells (NFAT)C2 inhibits Notch receptor signaling in osteoblasts.

NFATC2 NOTCH1

1.85e-052150223166323
Pubmed

Mice lacking inositol 1,4,5-trisphosphate receptors exhibit dry eye.

ITPR2 ITPR3

1.85e-052150224901844
Pubmed

Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization.

ITPR2 ITPR3

1.85e-052150233854148
Pubmed

Proximity to PML nuclear bodies regulates HIV-1 latency in CD4+ T cells.

EHMT2 PML

1.85e-052150223768491
Pubmed

Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors.

ITPR2 ITPR3

1.85e-052150219528657
Pubmed

Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction.

ITPR2 ITPR3

1.85e-05215028063813
Pubmed

IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism.

ITPR2 ITPR3

1.85e-052150216195467
Pubmed

KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity.

KDM2B KDM2A

1.85e-052150231363749
Pubmed

Common allosteric mechanisms between ryanodine and inositol-1,4,5-trisphosphate receptors.

RYR1 ITPR3

1.85e-052150221150295
Pubmed

PML promotes MHC class II gene expression by stabilizing the class II transactivator.

CIITA PML

1.85e-052150223007646
Pubmed

Inositol (1,4,5)-trisphosphate receptor links to filamentous actin are important for generating local Ca2+ signals in pancreatic acinar cells.

ITPR2 ITPR3

1.85e-052150215713744
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

EPPK1 SARM1 CELSR2 EHMT2 RPF2 PARD3 SDK1 AP3D1 NOTCH1

2.73e-05358150932460013
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

MYBBP1A EDC4 ANAPC1 SLC25A13 CLTC KDM2B AFDN KDM2A TAF2 TACC3 PARD3

2.84e-055491501138280479
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYBBP1A EPPK1 URB2 EDC4 IPO4 ITPR3 ANAPC1 SLC25A13 ATAD2B RPF2 CLTC AFDN

2.84e-056531501222586326
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

MYBBP1A EPPK1 GRN URB2 EDC4 ITPR2 ITPR3 PTPRF ZC3H4 HPRT1 SLC25A13 RPF2 CLTC AFDN HEATR5B

3.94e-0510241501524711643
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

MYBBP1A EPPK1 ABCF3 KTI12 PARVB PSMD13 EDC4 ECT2 MYO15B VPS33B ANAPC1

4.81e-055821501120467437
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR2 ITPR3

5.53e-053150210874040
Pubmed

New mutation causing sterility in the mouse.

H6PD TYRP1

5.53e-05315023220432
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR2 ITPR3

5.53e-053150220395455
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR2 ITPR3

5.53e-053150217437169
Pubmed

Selective activation of NFAT by promyelocytic leukemia protein.

NFATC2 PML

5.53e-053150218246125
Pubmed

A new dominant retinal degeneration (Rd4) associated with a chromosomal inversion in the mouse.

H6PD TYRP1

5.53e-05315029205110
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR2 ITPR3

5.53e-053150218547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR2 ITPR3

5.53e-053150236350267
Pubmed

The versatility and universality of calcium signalling.

ITPR2 ITPR3

5.53e-053150211413485
Pubmed

A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.

KDM2B KDM2A

5.53e-053150230033217
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

5.53e-053150226009177
Pubmed

A new allele at the Mup-1 locus controlling an electrophoretic variant of major urinary proteins in mice.

H6PD TYRP1

5.53e-05315026707444
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR2 ITPR3

5.53e-05315021693919
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR2 ITPR3

5.53e-053150223955339
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR2 ITPR3

5.53e-053150231979185
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR2 ITPR3

5.53e-053150224904548
Pubmed

Loss of polarity protein AF6 promotes pancreatic cancer metastasis by inducing Snail expression.

FOXE1 AFDN

5.53e-053150226013125
Pubmed

Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.

ITPR2 ITPR3

5.53e-05315029858485
Pubmed

Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.

CLTC TACC3

5.53e-053150220566684
Pubmed

Rescue of calcineurin Aα(-/-) mice reveals a novel role for the α isoform in the salivary gland.

ITPR2 ITPR3

5.53e-053150221435446
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR2 ITPR3

5.53e-05315029808793
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR2 ITPR3

5.53e-053150218194433
Pubmed

Kdm2a/b Lysine Demethylases Regulate Canonical Wnt Signaling by Modulating the Stability of Nuclear β-Catenin.

KDM2B KDM2A

5.53e-053150226004508
Pubmed

Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca(2+) release channels.

CABP1 ITPR3

5.53e-053150212032348
Pubmed

IP3 receptors regulate vascular smooth muscle contractility and hypertension.

ITPR2 ITPR3

5.53e-053150227777977
Pubmed

Striatal neurodevelopment is dysregulated in purine metabolism deficiency and impacts DARPP-32, BDNF/TrkB expression and signaling: new insights on the molecular and cellular basis of Lesch-Nyhan Syndrome.

HPRT1 PPP1R1B

5.53e-053150224804781
Pubmed

Centrosome/spindle pole-associated protein regulates cytokinesis via promoting the recruitment of MyoGEF to the central spindle.

ECT2 PLEKHG6

5.53e-053150219129481
Pubmed

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.

ITPR2 ITPR3

5.53e-053150217581770
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR2 ITPR3

5.53e-053150218241669
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR2 ITPR3

5.53e-053150219068129
Pubmed

Association of candidate genes with nonsyndromic clefts in Honduran and Colombian populations.

FOXE1 ABCA4

5.53e-053150222753311
Pubmed

KDM2B in polycomb repressive complex 1.1 functions as a tumor suppressor in the initiation of T-cell leukemogenesis.

KDM2B NOTCH1

5.53e-053150231471323
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

5.53e-053150217327232
Pubmed

Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.

RYR1 ITPR2

5.53e-053150223223241
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR2 ITPR3

5.53e-053150216014380
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR2 ITPR3

5.53e-053150217890015
Pubmed

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

ITPR2 ITPR3

5.53e-053150223983250
Pubmed

The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion.

AFDN PARD3

5.53e-053150230924770
Pubmed

A new genetic locus mapped from behavioral variation in mice: audiogenic seizure prone (ASP).

H6PD TYRP1

5.53e-05315025527661
Pubmed

Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.

ITPR2 ITPR3

5.53e-053150220427533
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

MYBBP1A EPPK1 PDPR URB2 IPO4 VPS33B EHMT2 HPRT1 SLC25A13 CLTC MAIP1 AP3D1

5.86e-057041501229955894
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

PDPR DPPA2 PSMD13 ITPR3 MAP7D1 PRCP KDM2B AP3D1 CARD14

5.94e-05396150926687479
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

CA12 MYBBP1A GRN URB2 PTPRF ANAPC1 CLTC TMEM209 AFDN MAIP1 TAF2 RMND1 MTCH2 MNT AP3D1 PML

6.78e-0512031501629180619
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYBBP1A ABCF3 AMBRA1 PSMD13 URB2 IPO4 ECT2 MAP7D1 VPS33B SLC25A13 RPF2 CLTC AFDN KDM2A TAF2 PARD3 AP3D1

7.97e-0513531501729467282
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MYBBP1A PDPR TTLL5 FASTKD1 SARM1 PSMD13 C2CD4C ITPR2 ITPR3 VPS33B EHMT2 ZC3H4 SLC25A13 RPF2 CLTC TMEM209 RMND1 MTCH2

8.42e-0514961501832877691
Pubmed

Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.

RYR1 ITPR3

1.10e-044150222100703
Pubmed

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.

ITPR2 ITPR3

1.10e-044150225215520
Pubmed

Abnormal taste perception in mice lacking the type 3 inositol 1,4,5-trisphosphate receptor.

ITPR2 ITPR3

1.10e-044150217925404
Pubmed

Mouse aldehyde dehydrogenase genetics: positioning of Ahd-1 on chromosome 4.

H6PD TYRP1

1.10e-04415027247077
Pubmed

IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.

ITPR2 ITPR3

1.10e-044150226193638
Pubmed

A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging.

CLTC TACC3

1.10e-044150221297582
Pubmed

PML regulates apoptosis at endoplasmic reticulum by modulating calcium release.

ITPR3 PML

1.10e-044150221030605
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR2 ITPR3

8.00e-053942297
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

WASF3 LAMA5 CAPN13 PTPRF ARHGAP44 PTPRQ AFDN PARD3

2.15e-07184150857c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

WASF3 LAMA5 CAPN13 PTPRF ARHGAP44 PTPRQ AFDN PARD3

2.15e-071841508d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

WASF3 LAMA5 CAPN13 PTPRF ARHGAP44 PTPRQ AFDN PARD3

2.75e-07190150830b50d183d7649146eb1e79b47ba897355f1998a
ToppCellfacs-Skin|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 ACP3 TENM2 ITPR3 PTPRF ARHGAP44 AFDN

3.92e-061911507ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXE1 ERN2 TENM2 CELSR2 PTPRQ CARD14

2.51e-051711506121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCellfacs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRN RYR1 PTPRF ARHGAP27 SARDH SDK1

2.68e-051731506ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCellfacs-Marrow-T-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRN RYR1 PTPRF ARHGAP27 SARDH SDK1

2.68e-05173150619a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)-|367C / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 ITPR3 CAPN13 ESYT3 PTPRF ACOXL

2.77e-051741506edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)|367C / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 ITPR3 CAPN13 ESYT3 PTPRF ACOXL

2.77e-05174150665539f69100db0b7d90b1b39ee15ab8281f86461
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

SETD6 EXTL1 ATG2A STARD9 PRKAG2 PML

2.86e-0517515062812ac2ef41d245db544697fb6da1883361c96e8
ToppCell368C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

UBE3B FASTKD1 URB2 MLH3 UCKL1 RNF32-DT

3.35e-051801506eb5a57604c7f2ad256c300085dbf5069d0ae1ad0
ToppCell368C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

UBE3B FASTKD1 URB2 MLH3 UCKL1 RNF32-DT

3.35e-051801506ddba4dc3bbcfe4e4a22400be73bbc62d3ff27d3c
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARVB ECT2 CELSR2 CEP295 TACC3 NOTCH1

3.56e-05182150639f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

WASF3 LAMA5 PTPRF ARHGAP44 PTPRQ AFDN

3.90e-0518515061c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

WASF3 LAMA5 PTPRF ARHGAP44 PTPRQ AFDN

4.02e-05186150609d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

WASF3 LAMA5 PTPRF ARHGAP44 PTPRQ AFDN

4.14e-05187150677f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA4 WASF3 DEPP1 NUDT17 C2CD4C ATAD2B

4.40e-0518915060739baad9a7da511dd3d7249f84299aee88370a1
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

LAMA5 CELSR2 ARHGAP44 AFDN PARD3 ACOXL

4.66e-051911506d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell367C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

LRRK1 H6PD ANKRD55 PTPRF ARNT2 KDM2B

4.80e-051921506e44e37e5aeba8628556020d05e1606b28e2faa4f
ToppCellfacs-Trachea-24m-Epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXE1 EPPK1 DEPP1 LAMA5 PTPRF CELSR2

4.94e-051931506ec49a83b24371579d4ad46aad91c25115aa226f9
ToppCellfacs-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXE1 EPPK1 ACP3 LAMA5 PTPRF PPP1R1B

5.08e-0519415063701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCellfacs-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXE1 EPPK1 ACP3 LAMA5 PTPRF PPP1R1B

5.08e-05194150665f9bf126be26114c2c3f4c46d48318986212a92
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 FREM1 ARHGAP44 PRKAG2 SDK1 ACOXL

5.08e-0519415064579b4a44f7c731553a284843c296866027d7c0e
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UACA LRRC32 DEPP1 PARVB AFDN NOTCH1

5.23e-05195150698d79f6a8a5cc86a219efe8db9f9535d7ad4c5be
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

WASF3 LAMA5 CAPN13 PTPRF ARHGAP44 PTPRQ

5.23e-051951506a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UACA LRRC32 DEPP1 PARVB AFDN NOTCH1

5.23e-051951506ea0627ffe1750dbdd48006d251c0ba4cadd32faf
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UACA LRRC32 DEPP1 PARVB AFDN NOTCH1

5.23e-0519515063b95a989adb99591b44704ff4c496a1c6cb0bb18
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Duct|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CA12 KLK6 URB2 NUDT17 PPP1R1B PNMA6A

5.23e-051951506fdbb4abc0c79a6aeace71bfa5a5c5576ca39d758
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 FREM1 ARHGAP44 PRKAG2 SDK1 ACOXL

5.23e-0519515063d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

WASF3 LAMA5 CAPN13 PTPRF ARHGAP44 PTPRQ

5.53e-0519715068d5097898dd01cedb04cb694cb480c931e08462c
ToppCellMonocytes-cDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

ITPRIPL2 ACP3 GRN CSF3R CIITA PRCP

5.53e-0519715063388c104af4c6a05988e102627e0c5e34d9dcc45
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

AMBRA1 ARHGAP44 PARD3 KIF13A SDK1 ACOXL

5.69e-0519815061996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellcontrol-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ITPRIPL2 GRN LRRK1 RYR1 CIITA PRCP

5.85e-05199150631825ba336603fe940dea6022e18ec25af110f4c
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

UACA LRRC32 PARVB PRCP AFDN PML

6.02e-05200150681e76508c9050d533853d5fd2f3097b27613d836
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

UACA LRRC32 PARVB PRCP AFDN PML

6.02e-0520015063b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UACA LRRC32 DEPP1 PARVB PRCP AFDN

6.02e-052001506fc0fd7b8e16eb593698084dca3f566d4d4bff381
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

UACA LRRC32 PARVB PRCP AFDN PML

6.02e-0520015064bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-MEP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IPO4 ZNF879 FREM1 TOMM20L PNMA6A

1.01e-0413715050bb5cccc31e7c44d44a2db3f59b68f9a81503151
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CABP1 PARVB SLC34A3 AFDN NOTCH1

1.12e-041401505b9aeb7dda7f377b580dd8a44912f300721437387
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 KLK6 AACS PRKAG2 DOP1A

1.50e-0414915057e295b2b82dea0754e98f8cef788e2781e5d641f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 KLK6 AACS PRKAG2 DOP1A

1.50e-041491505b4f77dc5f9d08b249fe5cd9a0acf86308c528ef4
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IPO4 KCNG2 NFATC2 CIITA KDM2B

1.64e-04152150587a7116d0064a6051bdf28ce1e48bfc168273e66
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT1_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

LAMA5 MYO15B PTPRF ARHGAP44 PPP1R1B

1.75e-0415415058a643d91896af9b630a715fb284c1523d01ad1a3
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RYR1 NFATC2 CIITA SLC25A13 TACC3

1.86e-041561505af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYBBP1A ZNF507 URB2 CELSR2 TARBP2

1.91e-041571505ffb8dd381e6b9adc5283fb49586e8bd63773c8d6
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYBBP1A ZNF507 URB2 CELSR2 TARBP2

1.91e-041571505c488ab1d6c6c7e5c2f4426805d1366b44711a031
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

URB2 H6PD CIITA ARHGAP44 PML

1.91e-041571505a426c54fd1545093d41426e9620862f71bd06f6b
ToppCellTCGA-Kidney-Solid_Tissue_Normal-Kidney-Kidney_normal_tissue-5|TCGA-Kidney / Sample_Type by Project: Shred V9

KLK6 ACP3 SLC34A3 TYRP1 PTPRQ

1.97e-04158150534b284a62cc3fb90429ce579fd8cb8a60178091b
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 DEPP1 EXTL1 H6PD SLC25A13

2.09e-041601505c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RYR1 NFATC2 CIITA SLC25A13 TACC3

2.15e-0416115050e2b54a63781397f6b99eb0e201fbb820cbd7cc6
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

URB2 KCNG2 DGLUCY CIITA KDM2B

2.34e-04164150554f8f11d2fa899005530c08e7a1ee728c7b0799c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRTG FREM1 OR4D2 PRKAG2 SDK1

2.34e-0416415056fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

SZT2 UBE3B PTPRF AFDN KDM2A

2.47e-04166150532d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCelldroplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WEE1 EXTL1 RYR1 CIITA DOP1A

2.54e-041671505f33cef917fa733adf6d5a9a9e989a4d9fd462a8f
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA12 TENM2 RYR1 CIITA PPP1R1B

2.62e-041681505b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA12 TENM2 RYR1 CIITA PPP1R1B

2.62e-041681505b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ACP3 LRRK1 RYR1 CIITA AFDN

2.62e-041681505d60f7cd8269f373827f49c7785002cb38e4570a9
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

PRTG ESYT3 PTPRF PPP1R1B ACOXL

2.62e-041681505e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PRTG ESYT3 PTPRF PPP1R1B ACOXL

2.62e-04168150516b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ACP3 LRRK1 RYR1 CIITA AFDN

2.69e-041691505ccd98f9005aa0a88bd49f153be4e7200cc3dd0ac
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IPO4 RYR1 EXD3 PIGC PTPRQ

2.91e-04172150580b565f6e37f38629f4cf89d5b053b3b8517244e
ToppCellfacs-Marrow-B-cells-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHBDF1 TMPRSS6 TTLL5 ANKRD55 ACOXL

2.91e-041721505a7fd4d61fb5017dce001d69d6b9a01e6cdf58828
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASNSD1 EPPK1 WASF3 PRCP RPF2

2.99e-0417315053c51e7bda1835c25915e50c801b0d643979971a3
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CABP1 ACP3 TYRP1 ARNT2 ACOXL

2.99e-0417315057a3115e7cf7e2f345192cde0656a7f0193594a5f
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASNSD1 EPPK1 WASF3 PRCP RPF2

2.99e-041731505a042f78a4c69fcc6b5ca76e9bf01e34cee54c81c
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CABP1 UACA LRRC32 DEPP1 ITPR2

3.07e-04174150518ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CABP1 FASTKD1 NUDT17 ESYT3 SLC25A13

3.16e-041751505aa168aeb9ad71aa6c0c28a0657c9eb92a0b28183
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 PARVB FREM1 ITPR2 CAPN13

3.16e-0417515051d8da48236549c01381f777ce5b2937f9f86acc2
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ECT2 RYR1 KCNG2 CIITA TACC3

3.16e-04175150573f25bd54309aed1480ddc44bdab518b17e71f92
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.C1ql3_(Hippocampus_Excitatory_Neuron)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CA12 KCNG2 ESYT3 TOMM20L

3.23e-049715041da964954a95c497ac4a24df1ea3575df5747025
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN1(Slc17a7)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CA12 KCNG2 ESYT3 TOMM20L

3.23e-04971504dd188763ba02337e4f25d56766eda886cffa810d
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CA12 KCNG2 ESYT3 TOMM20L

3.23e-04971504a0242258aad0766450ff52fe28278cbb2b8d63a0
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.C1ql3_(Hippocampus_Excitatory_Neuron)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CA12 KCNG2 ESYT3 TOMM20L

3.23e-0497150498a31b9bf0adcad1cb1d803bf7a23d49b4e1f2d5
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CABP1 TMPRSS6 EXTL1 RYR1 PPP1R1B

3.41e-041781505a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA12 TYRP1 PLEKHG6 CELSR2 ARNT2

3.41e-041781505ef490b45901b2e6dedb519540fa3ae4e4db3a9ba
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CABP1 TMPRSS6 EXTL1 RYR1 PPP1R1B

3.41e-0417815051bddbc083c36657bd6910f7466126ab325e88176
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRTG ANKRD55 KCNG2 PARD3 SDK1

3.41e-0417815053c973aac16988e88f5677d3d695dd772ccfd6570
ToppCellPBMC-Convalescent-Hematopoietic-Platelet|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AQP10 LRRC32 WASF3 PARVB PARD3

3.41e-041781505f5d83ad082e31d5601890d245b9fb4f9ef6a062b
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AQP10 LRRC32 WASF3 PARVB PARD3

3.41e-041781505a2a8fc14f492a4695e6991a357b6626145f1bf7f
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AQP10 LRRC32 WASF3 PARVB PARD3

3.50e-041791505510927794bbd21814eba75286e0801eb1fd2e8a6
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

ITPR3 ESYT3 CSF3R ARHGAP44 PPP1R1B

3.50e-041791505466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

ITPR3 ESYT3 CSF3R ARHGAP44 PPP1R1B

3.50e-041791505f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCellPBMC-Convalescent-Hematopoietic|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

AQP10 LRRC32 WASF3 PARVB PARD3

3.50e-0417915053b1616e974ea7792ff5c37da3b0281f28edfbb56
ToppCellPBMC-Convalescent-Hematopoietic|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AQP10 LRRC32 WASF3 PARVB PARD3

3.50e-04179150535271a4396a533f6d960ce55d171a32d9d2fd1a4
ToppCellPBMC-Convalescent-Hematopoietic-Platelet|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AQP10 LRRC32 WASF3 PARVB PARD3

3.50e-041791505906a5ebbbac660b6fd498ced09d0ada40a3e64af
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA5 CELSR2 ARHGAP44 PARD3 ACOXL

3.50e-041791505cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA5 PLEKHG6 PTPRF PPP1R1B ACOXL

3.50e-041791505ca70a5518c5a5392e088c103e0cb44aa084f5332
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA5 PLEKHG6 PTPRF PPP1R1B ACOXL

3.50e-041791505c451b074b04eb5d6c575c6abaedda579c6744bbf
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA12 TTLL5 LRRK1 NUDT17 ACOXL

3.59e-041801505be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCellCOVID-19_Convalescent-Hematopoietic_Mega-Platelet|COVID-19_Convalescent / Disease group, lineage and cell class

AQP10 LRRC32 WASF3 PARVB PARD3

3.59e-041801505deed53167504c91220b35a63366ed7d8f02a5254
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA12 TTLL5 LRRK1 NUDT17 ACOXL

3.59e-0418015053b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCellCOVID-19_Convalescent-Hematopoietic_Mega|COVID-19_Convalescent / Disease group, lineage and cell class

AQP10 LRRC32 WASF3 PARVB PARD3

3.59e-04180150517323d382ae322e388e230fdad13e3464ea73e8e
ToppCellcritical-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

AQP10 ZNF781 WASF3 FREM1 EXD3

3.68e-041811505f0d81ae74d3f32979624a94b2ef93774831a7970
ToppCellremission-Platelet|remission / disease stage, cell group and cell class

AQP10 LRRC32 DEPP1 PARVB PARD3

3.78e-04182150565e2798aacd670cbc3a8c8e9d1a2f7768513bb70
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERN2 CAPN13 PTPRF PTPRQ ACOXL

3.78e-041821505678eadd57e7e830fc2bf9fd35616d3badce01705
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERN2 CAPN13 PTPRF PTPRQ ACOXL

3.78e-0418215058d1229fa5aa6e2e38f2ac6fe4f4dc89752fe9344
ToppCellControl-Epithelial-Basal|Control / Disease state, Lineage and Cell class

FOXE1 CAPN13 PTPRQ PARD3 SDK1

3.78e-041821505caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UACA DEPP1 PARVB ITPR3 NOTCH1

3.87e-0418315053427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 CABP1 ACP3 ITPR2 ARNT2

3.87e-04183150531ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 H6PD PTPRF SARDH PARD3

3.87e-041831505d0721c6aa426953a520d40e976b6e65aa7ca65e8
DrugFlucytosine [2022-85-7]; Up 200; 31uM; HL60; HT_HG-U133A

FOXE1 SZT2 TTLL5 LRRK1 ITPR3 SPATA2L MLH3 DNAH17 AFDN SARDH CARD14

7.24e-08199147113073_UP
DrugCefaclor [70356-03-5]; Down 200; 10.4uM; PC3; HT_HG-U133A

SZT2 TTLL5 SARM1 DEPP1 ERN2 LINS1 PIGC DNAH17 AFDN PML

6.66e-07198147106622_DN
DrugCinoxacin [28657-80-9]; Down 200; 15.2uM; PC3; HT_HG-U133A

EPPK1 UBE3B AMBRA1 LRRK1 H6PD ERN2 LINS1 PIGC CELSR2

5.13e-0619514795783_DN
Diseaseobsolete_red blood cell distribution width

ASNSD1 AQP10 TMPRSS6 UBE3B PARVB ECT2 ESYT3 VPS33B ZC3H4 ATAD2B KDM2B AFDN ARHGAP27 RMND1 PRKAG2 SPACA3 NOTCH1 ACOXL

1.13e-04134714518EFO_0005192
Diseaseviral infectious disease (implicated_via_orthology)

EHMT2 PTPRQ

2.38e-0451452DOID:934 (implicated_via_orthology)
Disease17-beta-hydroxysteroid dehydrogenase 14 measurement

SARM1 EHMT2

2.38e-0451452EFO_0802231
DiseaseAgouti-signaling protein measurement

SARM1 PARD3

2.38e-0451452EFO_0801357
Diseaseliver iron measurement

ASNSD1 TMPRSS6 OR2W6P

5.69e-04331453EFO_0010056
DiseaseParkinson disease, disease progression measurement

AQP10 AACS PARD3

9.33e-04391453EFO_0008336, MONDO_0005180
Diseaseinterventricular septum thickness

ITPR2 KDM2B

1.05e-03101452EFO_0009287
Diseaseceramide measurement

TTLL5 ERN2 ATP10D CELSR2 PPP1R1B SDK1

1.11e-032351456EFO_0010222
Diseasemultisite chronic pain

ITPR3 VPS33B SLC25A13 SDK1

1.26e-03951454EFO_0010100
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR2 ITPR3

1.53e-03121452DOID:1441 (implicated_via_orthology)
Diseasecomplement C1q tumor necrosis factor-related protein 1 measurement

GRN CELSR2

1.53e-03121452EFO_0801493
Diseasegranulins measurement

GRN CELSR2

1.53e-03121452EFO_0008141
Diseasetotal cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement

ZNF507 PIGC ZC3H4

1.81e-03491453EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
DiseaseDupuytren Contracture

WASF3 LRRK1 NFATC2 SDK1

2.02e-031081454EFO_0004229
Diseaseresponse to cisplatin, platinum measurement

INTS7 ECT2 SARDH

2.27e-03531453EFO_0010154, GO_0072718
Diseaseneuroblastoma

CA12 LAMA5 TENM2 CEP295

2.62e-031161454EFO_0000621
Diseasepolyp of colon

NID2 LAMA5 PLEKHG6

2.66e-03561453MONDO_0021400
Diseasechronic lymphocytic leukemia

FREM1 OR6V1 PISD ACOXL

2.87e-031191454EFO_0000095
DiseaseDisorder of eye

ABCA4 GRN FREM1 TYRP1 FOXE3

4.04e-032121455C0015397
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Positive

TTLL5 ACP3 WASF3 ELF2

4.05e-031311454C4704862
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Negative

TTLL5 ACP3 WASF3 ELF2

4.05e-031311454C4552091
DiseaseJuvenile arthritis

TTLL5 ACP3 WASF3 ELF2

4.05e-031311454C3495559
DiseaseJuvenile psoriatic arthritis

TTLL5 ACP3 WASF3 ELF2

4.05e-031311454C3714758
Diseasehypertension

SZT2 SARM1 VPS33B NFATC2 PRKAG2 MTCH2

4.20e-033071456EFO_0000537
Diseaseage at initiation of smoking

ITPR3 PPP1R1B SDK1

4.24e-03661453EFO_0021784
Diseaseunipolar depression, mood disorder

ZNF507 ATAD2B ARHGAP27 MTCH2

4.39e-031341454EFO_0003761, EFO_0004247
DiseaseJuvenile-Onset Still Disease

TTLL5 ACP3 WASF3 ELF2

4.50e-031351454C0087031
Diseasepalmitoylcarnitine measurement

FAM47B ACOXL

4.74e-03211452EFO_0021044

Protein segments in the cluster

PeptideGeneStartEntry
SMFHSVRRVLADPEI

URB2

1201

Q14146
DVLHTLTGAMSLLRR

AFDN

761

P55196
HSGLDSLISMRLVLR

ESYT3

566

A0FGR9
RSLRVHIPDLSSFAM

PRKAG2

31

Q9UGJ0
ASMVSAPLETLRLER

C16orf86

171

Q6ZW13
LLAAMRPSEEHVASR

ANKRD13D

211

Q6ZTN6
ILSQFMDTLRTHPER

ABCA4

131

P78363
ILSDMSPRIQEFIHR

ABCA4

276

P78363
AIRMGLSARHVPSLI

AACS

606

Q86V21
AESLARVLPDMVSLR

CIITA

1061

P33076
MRSRLLLSVAHLPTI

DEPP1

1

Q9NTK1
LEKMPARRASLSHPR

GRN

426

P28799
KMLATRSLRVPAHIS

ABCF3

221

Q9NUQ8
APAEIMGHLRIRSLL

AQP10

6

Q96PS8
ATRPDMIRILSAALH

DOP1A

261

Q5JWR5
PSSRVALMVLCETHR

EHMT2

471

Q96KQ7
LRIFLKMPDSDRHLS

CAPN13

471

Q6MZZ7
LHAATAEPDMRLLTV

ANKRD55

131

Q3KP44
RLLAICHTVMVRESP

ATP8B3

566

O60423
THSITLRLEDMSPER

CELSR2

1126

Q9HCU4
VMVGLASRRILLHPS

AMBRA1

956

Q9C0C7
ADPFLHRLRPMLSSA

CABP1

201

Q9NZU7
AMLAESPHTRRKESL

C2CD4C

151

Q8TF44
RGPHMLSTAVRIHLD

ATG2A

1041

Q2TAZ0
LLHILPFDSVRKRMS

ATP10D

766

Q9P241
RLMPHLATALALTFV

ACOXL

286

Q9NUZ1
HTLEAMLRPRVTTLP

AP3D1

501

O14617
APLDHLPLNRITTMR

ARNT2

246

Q9HBZ2
REMIARSAATLITHP

MTCH2

126

Q9Y6C9
ARPTLRMLANHALST

RNF32-DT

6

Q8NI28
RRLSLMLHGLVTPSL

EDC4

1386

Q6P2E9
TPKRALRRALMTSHG

ECT2

846

Q9H8V3
IHSNDPVARAITLRM

INTS7

111

Q9NVH2
PADRMLSALQVALIH

SLC34A3

436

Q8N130
SGPRMRVRDSTLHLK

ITPR2

1846

Q14571
RAILLPMDLDAHISS

ITPR3

1536

Q14573
DMSITRLLSIHIPAL

ANAPC1

1221

Q9H1A4
MAAPLSLADAHRSVL

NFATC2

771

Q13469
SVMAFDRLIAISRPL

OR4D2

116

P58180
RMHDGTTPLILAARL

NOTCH1

1991

P46531
SPDHVILRAASLVIM

LINS1

376

Q8NG48
MALAARLLPQFLHSR

MAIP1

1

Q8WWC4
HLRFTRPLTMAELSR

KTI12

306

Q96EK9
DGRARPLVLHMSTLL

NUDT17

251

P0C025
ANVPADTMLRHLRAT

LRRK1

1281

Q38SD2
RAVMSSGHALSPIIR

ATAD2B

666

Q9ULI0
HISMPLQTDLRKFRS

ERN2

826

Q76MJ5
MPRRSLHAAAVLLLV

CA12

1

O43570
LPETHSLDNRRTLML

IFNA1;

26

P01562
VAMALFAPLVHLAER

KCNG2

331

Q9UJ96
VRQRIEALSLMHPSI

MLH3

171

Q9UHC1
IVLLSALDSRLHTPM

OR2W6P

51

Q8NHA6
HFEPLLSSLLRRMPE

PDPR

331

Q8NCN5
HLRLVLPITRRMASL

FAM47B

396

Q8NA70
HLERRPLPSSMQLAV

FREM1

1891

Q5H8C1
DPMSVLLARSLEVRH

PRCP

466

P42785
LARLAHTLPVEEPRM

MNT

46

Q99583
LLMHPVLESLRNTDR

PSMD13

216

Q9UNM6
LSMHVLPRSSRGLLL

LAMA5

3366

O15230
LLLPASPVRMHSSRL

PABIR1

71

Q96E09
SSLHMPERAVFRLRK

MYBBP1A

436

Q9BQG0
FIPHGLIMDRTERLA

HPRT1

36

P00492
VAITPRMLADLLFTH

OR10H3

76

O60404
VAITPRMLADLLSTH

OR10H4

76

Q8NGA5
KLVRASRAHDTTPMI

PTPRQ

2216

Q9UMZ3
GAILMIVISDPRLHS

OR12D1

41

P0DN82
LVSLAMHFRAPIRLP

PARVB

186

Q9HBI1
AHRRKSMEASLTVIP

PRTG

211

Q2VWP7
FLAMVPTVLSRAHLD

OR6V1

151

Q8N148
LTRLTRHTFRDMPAL

LRRC32

161

Q14392
HSSERALERVPSMEL

MYO15B

411

Q96JP2
ISPEGLAIDHIRRTM

NID2

1186

Q14112
MRAAPLLLARAASLS

ACP3

1

P15309
LFLKAGHTSLRPMRA

PLEKHG6

721

Q3KR16
TLEERPLLGSLRHMA

KCTD18

236

Q6PI47
DATVIPHLMALLSRS

ARMC8

146

Q8IUR7
TSVLLHPSMAARLAA

HEATR5B

451

Q9P2D3
ITDATLRLIIRHMPL

KDM2A

1051

Q9Y2K7
TDASLRLIIRHMPLL

KDM2B

1226

Q8NHM5
EVLHSPRLTNSAMRA

CARD14

56

Q9BXL6
LDRMCSTLRHEIPEA

DNAH17

1661

Q9UFH2
SPSRSARVQFHLMEL

FASTKD1

651

Q53R41
ALVMPLSLVHELSGR

HTR5A

91

P47898
ESRGPALTRLHAMAR

CSF3R

426

Q99062
ALLHMESPTCLRDSR

ELF2

101

Q15723
IVDRLMTPTLSFLAR

MAP7D1

296

Q3KQU3
DSMVIATLADRHIPL

ASNSD1

331

Q9NWL6
VMERLHLALRPICSL

SDR42E2

316

A6NKP2
MPFTLHLRSRLPSAI

DGLUCY

1

Q7Z3D6
HRRMSLSLPLINRAK

H6PD

726

O95479
SVLLHPQEAAARIRM

CEP295

491

Q9C0D2
DSRMARLEVIELPHS

SDK1

656

Q7Z5N4
MVSALRGAPLIRVHS

SPACA3

1

Q8IXA5
PSMLQHLLRRLVFDV

RYR1

2616

P21817
HSPEREMGLLLLSVV

IPO4

131

Q8TEX9
PTTHRRMISLFLLPA

DPPA2

251

Q7Z7J5
LLAHSSDPVEMRRLN

PTPRF

1306

P10586
SLILLTIHRMPSAEG

OR2T11

216

Q8NH01
VLRANMPLHVRRSSD

PARD3

131

Q8TEW0
CRLSMAVRLIPAVHL

ITPRIPL2

301

Q3MIP1
SHPAAMELVLRKRIA

KIF13A

1261

Q9H1H9
AHMVSRFLLPSILSE

SZT2

2546

Q5T011
LRDPQTHRILSPSMA

TACC3

61

Q9Y6A5
RRDSHRLMVTALPPA

SPATA2L

131

Q8IUW3
LIAMAIAHAPERRLT

FOXE1

61

O00358
HSAMIIDETPLTRRC

TAF2

331

Q6P1X5
HFLSFLSSMRRPILA

PML

661

P29590
ADIMLPALRSRVTVH

EPPK1

876

P58107
AMALAHAPGRRLTLA

FOXE3

81

Q13461
LDRSELERSHLMLPL

RHBDF1

306

Q96CC6
VRSLPAPNHDTLRML

ARHGAP27

811

Q6ZUM4
MEAHPDLFSLRVRSL

SETD6

196

Q8TBK2
MPATLLRAVARSHHI

RMND1

1

Q9NWS8
LKIRRDSSGMPRHLL

TENM2

1636

Q9NT68
TSLHPQRMKALARAL

STARD9

2196

Q9P2P6
SRLPRSLHAFIMVTF

PIGC

191

Q92535
LGSTLRLSPLEHMRR

ARHGAP44

786

Q17R89
AFGHMPLLSSRLRLD

EXTL1

641

Q92935
EMGPSLDLVLRRTHL

RPF2

216

Q9H7B2
MASLSRALRVAAAHP

SARDH

1

Q9UL12
LRQMLTRAHLTEPLD

PNMA6A

286

P0CW24
IDFRDIMVTIRPHVL

SLC25A13

181

Q9UJS0
DLLMVLSPRLDHTRA

CLTC

1421

Q00610
SSMFRVLQRHLTLDP

TRIML2

241

Q8N7C3
RALDMAKRTTHPLFV

TYRP1

146

P17643
RRPSAMALVKHSVLL

WEE1

556

P30291
ARILTAAREMLHSPL

SARM1

536

Q6SZW1
DVPALADRVRHSMLT

AGPAT1

246

Q99943
RKIHTAPARTMFLLR

PISD

51

Q9UG56
PISDARSDLLAAIRM

WASF3

436

Q9UPY6
VVSLAAMREPSLLRF

USP20

696

Q9Y2K6
ALQSMPTLDPRLHRA

ZC3H4

1001

Q9UPT8
AHPSASLIDRTIKMR

TMEM209

6

Q96SK2
HMQSRSMLRPLELSL

UACA

416

Q9BZF9
RLHSLAAEALVTMPI

ZNF507

491

Q8TCN5
TPERLTVLESHDMLR

UBE3B

271

Q7Z3V4
MELAPLGSLHARLTA

TNK1

196

Q13470
MARRLLPAHVQESVT

ZNF879

1

B4DU55
RLMRLLIEHALSFLP

UCKL1

356

Q9NWZ5
MPSVRSLLRLLAAAA

TOMM20L

1

Q6UXN7
MLLRVHTVPLDARDG

TARBP2

221

Q15633
RRPTPAMLFRLSEHS

PPP1R1B

31

Q9UD71
DLKTPFMSHILRRTV

WDR87

2461

Q6ZQQ6
SNARRPSSIMHILFD

ZNF781

316

Q8N8C0
HIDRQVSPIESLRLM

VPS33B

386

Q9H267
LQHSLRMVLPSRRLA

TTLL5

726

Q6EMB2
HRRLMLSPEVVQALL

TMPRSS6

161

Q8IU80
RSIHCAPMLSDILRR

ZSWIM4

871

Q9H7M6
SGLVLTRMIPLDLVH

GARIN5B

96

Q8N5Q1
ASHDQDIMLLRLARP

KLK6

101

Q92876
DLLLVHRQMRVASVP

EXD3

491

Q8N9H8
MVLRRLLAALLHSPQ

NCBP2AS2

1

Q69YL0