Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphospholipid binding

AGAP5 AMER3 AGAP9 TEC AGAP4 AGAP6 SH3PXD2A

2.39e-04548467GO:0005543
MousePhenofused cornea and lens

AGAP5 AGAP9 AGAP4 AGAP6

3.79e-0724364MP:0001307
MousePhenoabsent pinna reflex

AGAP5 AGAP9 GAS2L2 AGAP4 AGAP6

3.01e-0689365MP:0006358
MousePhenocataract

KATNIP PRAMEF33 AGAP5 PRAMEF17 AGAP9 HMCN1 NRCAM AGAP4 AGAP6

3.37e-06497369MP:0001304
MousePhenoabnormal pinna reflex

AGAP5 AGAP9 GAS2L2 AGAP4 AGAP6

5.62e-06101365MP:0001485
MousePhenoabnormal left vena cava superior connection

GAS2L2 SH3PXD2A

6.45e-062362MP:0013976
MousePhenoabnormal lens morphology

KATNIP PRAMEF33 AGAP5 PRAMEF17 AGAP9 HMCN1 NRCAM GAS2L2 AGAP4 AGAP6

7.12e-066993610MP:0001303
MousePhenoabnormal anterior eye segment morphology

KATNIP PRAMEF33 AGAP5 PRAMEF17 AGAP9 HMCN1 NRCAM GAS2L2 ITFG2 AGAP4 MUC5AC AGAP6

1.31e-0511173612MP:0005193
MousePhenodecreased T follicular helper cell number

BCL6 ITFG2

3.86e-054362MP:0010187
MousePhenoabnormal snout morphology

AGAP5 AGAP9 GAS2L2 AGAP4 AGAP6 SH3PXD2A

4.47e-05257366MP:0000443
MousePhenoabnormal lens development

AGAP5 AGAP9 AGAP4 AGAP6

4.61e-0578364MP:0005545
MousePhenocornea opacity

AGAP5 AGAP9 AGAP4 MUC5AC AGAP6

5.07e-05159365MP:0001314
MousePhenoperimembraneous ventricular septal defect

SOX4 GAS2L2 SH3PXD2A TLL1

8.81e-0592364MP:0010418
MousePhenoabnormal interventricular septum membranous part morphology

SOX4 GAS2L2 SH3PXD2A TLL1

9.19e-0593364MP:0008823
MousePhenoabnormal vitreous body morphology

SOX4 PRAMEF33 AGAP5 PRAMEF17 AGAP9 AGAP4 AGAP6

9.42e-05429367MP:0002699
MousePhenoabnormal superior vena cava morphology

GAS2L2 SH3PXD2A

9.61e-056362MP:0006064
MousePhenoabnormal iris morphology

AGAP5 AGAP9 ITFG2 AGAP4 AGAP6

1.24e-04192365MP:0001322
MousePhenodouble inlet heart left ventricle

SH3PXD2A TLL1

1.34e-047362MP:0010433
MousePhenoabnormal anterior uvea morphology

AGAP5 AGAP9 ITFG2 AGAP4 AGAP6

1.46e-04199365MP:0005194
MousePhenoabnormal eye development

SOX4 AGAP5 AGAP9 GAS2L2 AGAP4 AGAP6 SH3PXD2A

1.94e-04482367MP:0001286
MousePhenopersistence of hyaloid vascular system

SOX4 AGAP5 AGAP9 AGAP4 AGAP6

2.49e-04223365MP:0001289
MousePhenoincreased circulating potassium level

AGAP5 AGAP9 AGAP4 AGAP6

2.54e-04121364MP:0005627
MousePhenoabnormal ear physiology

PRAMEF33 AGAP5 MUC5B PRAMEF17 AGAP9 GAS2L2 AGAP4 AGAP6

2.82e-04684368MP:0003878
MousePhenoincreased circulating alkaline phosphatase level

SOX4 AGAP5 AGAP9 MPIG6B AGAP4 AGAP6 SH3PXD2A

3.31e-04526367MP:0002968
MousePhenoabnormal T follicular helper cell number

BCL6 ITFG2

3.50e-0411362MP:0010185
MousePhenoabnormal uvea morphology

AGAP5 AGAP9 ITFG2 AGAP4 AGAP6

3.56e-04241365MP:0005197
MousePhenohearing/vestibular/ear phenotype

PRAMEF33 AGAP5 MUC5B PRAMEF17 AGAP9 GAS2L2 AGAP4 AGAP6 SH3PXD2A

3.69e-04905369MP:0005377
MousePhenoabnormal facial morphology

AGAP5 TMEM53 AGAP9 GAS2L2 AGAP4 ZNF414 AGAP6 SH3PXD2A TLL1

3.84e-04910369MP:0003743
MousePhenoabnormal T follicular helper cell morphology

BCL6 ITFG2

4.19e-0412362MP:0010184
MousePhenoabnormal thymus topology

GAS2L2 SH3PXD2A

4.19e-0412362MP:0013936
MousePhenoincreased circulating enzyme level

SOX4 BNIP5 PRAMEF33 AGAP5 PRAMEF17 AGAP9 MPIG6B AGAP4 AGAP6 SH3PXD2A

4.45e-0411403610MP:0014450
MousePhenoincreased enzyme/coenzyme level

SOX4 BNIP5 PRAMEF33 AGAP5 PRAMEF17 AGAP9 MPIG6B AGAP4 AGAP6 SH3PXD2A

4.71e-0411483610MP:0014448
MousePhenoimpaired mucociliary clearance

MUC5B GAS2L2

4.94e-0413362MP:0010752
MousePhenoabnormal auditory brainstem response

PRAMEF33 AGAP5 PRAMEF17 AGAP9 GAS2L2 AGAP4 AGAP6

5.72e-04576367MP:0004738
MousePhenoabnormal Mullerian duct topology

GAS2L2 SH3PXD2A

5.75e-0414362MP:0013852
MousePhenoabnormal vertebral body morphology

TMEM53 GAS2L2 SH3PXD2A

6.42e-0466363MP:0000141
MousePhenoabnormal hearing electrophysiology

PRAMEF33 AGAP5 PRAMEF17 AGAP9 GAS2L2 AGAP4 AGAP6

6.87e-04594367MP:0006335
MousePhenofused dorsal root ganglion

GAS2L2 SH3PXD2A

7.56e-0416362MP:0000963
MousePhenopersistent right dorsal aorta

SOX4 SH3PXD2A

7.56e-0416362MP:0010572
MousePhenoabnormal mucociliary clearance

MUC5B GAS2L2

7.56e-0416362MP:0001947
MousePhenoabsent stapedial artery

GAS2L2 SH3PXD2A

8.56e-0417362MP:0004666
MousePhenoabnormal conotruncal ridge morphology

SOX4 TLL1

8.56e-0417362MP:0010585
MousePhenoostium primum atrial septal defect

SH3PXD2A TLL1

8.56e-0417362MP:0010404
MousePhenoabnormal heart position or orientation

GAS2L2 SH3PXD2A TLL1

8.97e-0474363MP:0006065
MousePhenoabnormal circulating potassium level

AGAP5 AGAP9 AGAP4 AGAP6

9.38e-04171364MP:0002668
MousePhenoabnormal conotruncus morphology

SOX4 TLL1

9.61e-0418362MP:0010583
MousePhenoabnormal circulating alkaline phosphatase level

SOX4 AGAP5 AGAP9 MPIG6B AGAP4 AGAP6 SH3PXD2A

1.06e-03639367MP:0000202
MousePhenoabnormal hearing physiology

PRAMEF33 AGAP5 PRAMEF17 AGAP9 GAS2L2 AGAP4 AGAP6

1.10e-03643367MP:0001963
MousePhenoabnormal dorsal aorta morphology

SOX4 SH3PXD2A TLL1

1.17e-0381363MP:0004787
MousePhenoabnormal skin coloration

AGAP5 AGAP9 AGAP4 AGAP6

1.18e-03182364MP:0011239
MousePhenoabnormal stapedial artery morphology

GAS2L2 SH3PXD2A

1.19e-0320362MP:0004665
MousePhenodecreased IgG2a level

SIGLEC16 BCL6 ITFG2

1.30e-0384363MP:0008496
MousePhenoincreased male germ cell apoptosis

PRAMEF33 PRAMEF17 BCL6 KCTD19

1.36e-03189364MP:0014052
MousePhenoabnormal mouth morphology

AGAP5 AGAP9 GAS2L2 AGAP4 AGAP6 SH3PXD2A TLL1

1.39e-03670367MP:0000452
MousePhenoabnormal potassium level

AGAP5 AGAP9 AGAP4 AGAP6

1.55e-03196364MP:0020887
MousePhenoabnormal potassium ion homeostasis

AGAP5 AGAP9 AGAP4 AGAP6

1.61e-03198364MP:0011978
MousePhenoabnormal middle ear morphology

MUC5B GAS2L2 SH3PXD2A

1.68e-0392363MP:0000049
MousePhenoabnormal head morphology

AGAP5 TMEM53 AGAP9 GAS2L2 AGAP4 ZNF414 AGAP6 SH3PXD2A TLL1

1.71e-031120369MP:0000432
MousePhenoabnormal sphenoid bone morphology

TMEM53 GAS2L2 SH3PXD2A

1.85e-0395363MP:0000104
MousePhenoabnormal circulating enzyme level

SOX4 BNIP5 PRAMEF33 AGAP5 PRAMEF17 AGAP9 MPIG6B AGAP4 AGAP6 SH3PXD2A

1.88e-0313723610MP:0001570
MousePhenoabnormal semilunar valve morphology

SOX4 SH3PXD2A TLL1

1.96e-0397363MP:0002746
MousePhenodecreased spleen germinal center number

BCL6 ITFG2

2.02e-0326362MP:0008482
MousePhenoabnormal cornea morphology

AGAP5 AGAP9 AGAP4 MUC5AC AGAP6

2.31e-03366365MP:0001312
MousePhenodiaphragmatic hernia

SH3PXD2A DNASE2

2.51e-0329362MP:0003924
MousePhenoincreased circulating protein level

SOX4 BNIP5 PRAMEF33 AGAP5 PRAMEF17 AGAP9 MPIG6B AGAP4 AGAP6 SH3PXD2A

2.61e-0314333610MP:0014501
MousePhenodecreased T-helper cell number

BCL6 ITFG2

2.68e-0330362MP:0013764
MousePhenoabnormal enzyme/coenzyme level

SOX4 BNIP5 PRAMEF33 AGAP5 PRAMEF17 AGAP9 MPIG6B AGAP4 AGAP6 SH3PXD2A

2.86e-0314513610MP:0005319
MousePhenoabnormal skin morphology

PRAMEF33 AGAP5 MUC5B PRAMEF17 AGAP9 RB1CC1 AGAP4 AGAP6 TLL1 TTLL11

2.92e-0314553610MP:0002060
MousePhenoabnormal cerebral artery morphology

GAS2L2 SH3PXD2A

3.05e-0332362MP:0013821
MousePhenoabnormal nasal cavity morphology

GAS2L2 SH3PXD2A

3.05e-0332362MP:0002237
MousePhenoabnormal male germ cell apoptosis

PRAMEF33 PRAMEF17 BCL6 KCTD19

3.05e-03236364MP:0008280
MousePhenodecreased B cell number

SIGLEC16 SOX4 ACSL3 BCL6 ITFG2

3.18e-03394365MP:0005017
MousePhenoabnormal cranial foramen morphology

TMEM53 SH3PXD2A

3.24e-0333362MP:0030310
MousePhenoabnormal biliary tract morphology

SOX4 GAS2L2 SH3PXD2A

3.34e-03117363MP:0005083
MousePhenoabnormal male germ cell physiology

PRAMEF33 PRAMEF17 BCL6 KCTD19

3.44e-03244364MP:0020362
MousePhenodecreased IgG2 level

SIGLEC16 BCL6 ITFG2

3.58e-03120363MP:0013804
MousePhenoabnormal heart ventricle morphology

SOX4 PPP1R14D BCL6 RB1CC1 GAS2L2 SH3PXD2A TLL1

3.62e-03793367MP:0005294
MousePhenoliver hemorrhage

RB1CC1 TLL1

3.64e-0335362MP:0003888
MousePhenoabnormal basicranium morphology

TMEM53 GAS2L2 SH3PXD2A

3.84e-03123363MP:0010029
DomainArfGap

AGAP5 AGAP9 AGAP4 AGAP6

5.04e-0729424SM00105
DomainARFGAP

AGAP5 AGAP9 AGAP4 AGAP6

5.04e-0729424PS50115
DomainArfGAP

AGAP5 AGAP9 AGAP4 AGAP6

5.04e-0729424IPR001164
DomainArfGap

AGAP5 AGAP9 AGAP4 AGAP6

5.04e-0729424PF01412
DomainWxxW_domain

MUC5B MUC5AC

7.36e-056422IPR025155
DomainMucin2_WxxW

MUC5B MUC5AC

7.36e-056422PF13330
DomainTIL

MUC5B MUC5AC

3.21e-0412422PF01826
DomainC8

MUC5B MUC5AC

3.21e-0412422PF08742
DomainUnchr_dom_Cys-rich

MUC5B MUC5AC

3.79e-0413422IPR014853
DomainC8

MUC5B MUC5AC

3.79e-0413422SM00832
DomainPH

AGAP5 AGAP9 TEC AGAP4 AGAP6

3.82e-04278425SM00233
DomainPH_DOMAIN

AGAP5 AGAP9 TEC AGAP4 AGAP6

3.88e-04279425PS50003
DomainPH_domain

AGAP5 AGAP9 TEC AGAP4 AGAP6

3.95e-04280425IPR001849
DomainTIL_dom

MUC5B MUC5AC

4.42e-0414422IPR002919
DomainGlyco_hormone_CN

MUC5B MUC5AC

5.09e-0415422IPR006208
DomainCys_knot

MUC5B MUC5AC

5.09e-0415422PF00007
DomainVWFD

MUC5B MUC5AC

5.81e-0416422PS51233
DomainVWD

MUC5B MUC5AC

5.81e-0416422SM00216
DomainVWF_type-D

MUC5B MUC5AC

5.81e-0416422IPR001846
DomainVWD

MUC5B MUC5AC

5.81e-0416422PF00094
DomainCTCK_1

MUC5B MUC5AC

7.38e-0418422PS01185
DomainVWC_out

MUC5B MUC5AC

8.24e-0419422SM00215
DomainCT

MUC5B MUC5AC

1.11e-0322422SM00041
DomainCys_knot_C

MUC5B MUC5AC

1.43e-0325422IPR006207
DomainCTCK_2

MUC5B MUC5AC

1.43e-0325422PS01225
Domain-

AGAP5 AGAP9 TEC AGAP4 AGAP6

1.76e-033914252.30.29.30
DomainVWC

MUC5B MUC5AC

1.80e-0328422PF00093
Domain-

AGAP5 AGAP9 AGAP4 AGAP6

2.29e-032484241.25.40.20
DomainAnkyrin_rpt-contain_dom

AGAP5 AGAP9 AGAP4 AGAP6

2.49e-03254424IPR020683
DomainANK_REP_REGION

AGAP5 AGAP9 AGAP4 AGAP6

2.49e-03254424PS50297
DomainPH_dom-like

AGAP5 AGAP9 TEC AGAP4 AGAP6

2.56e-03426425IPR011993
DomainVWFC_1

MUC5B MUC5AC

2.96e-0336422PS01208
DomainVWC

MUC5B MUC5AC

3.30e-0338422SM00214
DomainVWFC_2

MUC5B MUC5AC

3.30e-0338422PS50184
DomainVWF_dom

MUC5B MUC5AC

4.02e-0342422IPR001007
DomainCUB

CSMD2 TLL1

5.43e-0349422PF00431
DomainBTB

BCL6 KCTD19 KCTD16

5.55e-03160423PS50097
DomainCUB

CSMD2 TLL1

5.65e-0350422SM00042
DomainSushi

CFHR5 CSMD2

6.10e-0352422PF00084
Domain-

CSMD2 TLL1

6.10e-03524222.60.120.290
DomainCUB

CSMD2 TLL1

6.33e-0353422PS01180
DomainBTB_2

KCTD19 KCTD16

6.33e-0353422PF02214
DomainT1-type_BTB

KCTD19 KCTD16

6.33e-0353422IPR003131
DomainCCP

CFHR5 CSMD2

6.56e-0354422SM00032
DomainSUSHI

CFHR5 CSMD2

7.04e-0356422PS50923
DomainSushi_SCR_CCP_dom

CFHR5 CSMD2

7.29e-0357422IPR000436
DomainCUB_dom

CSMD2 TLL1

7.29e-0357422IPR000859
DomainSKP1/BTB/POZ

BCL6 KCTD19 KCTD16

8.76e-03189423IPR011333
Pubmed

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

AGAP5 AGAP9 AGAP4 AGAP6

3.67e-10947412640130
Pubmed

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

AGAP5 AGAP9 AGAP4 AGAP6

6.11e-101047420664521
Pubmed

AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.

AGAP5 AGAP9 AGAP4 AGAP6

9.59e-101147415381706
Pubmed

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.

AGAP5 AGAP9 AGAP4 AGAP6

2.07e-091347427713690
Pubmed

GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

AGAP5 AGAP9 AGAP4 AGAP6

2.90e-091447422453919
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5B MUC5AC

1.79e-0624727513696
Pubmed

Mucin deficiency causes functional and structural changes of the ocular surface.

MUC5B MUC5AC

1.79e-06247223272068
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5B MUC5AC

1.79e-06247231030254
Pubmed

Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.

MUC5B MUC5AC

1.79e-06247227729120
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5B MUC5AC

1.79e-06247234058148
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5B MUC5AC

1.79e-06247237146737
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5B MUC5AC

1.79e-06247223527003
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5B MUC5AC

1.79e-06247214988081
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5B MUC5AC

1.79e-06247216540890
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5B MUC5AC

1.79e-06247215563276
Pubmed

De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

MUC5B MUC5AC

1.79e-06247236111525
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5B MUC5AC

1.79e-06247217621824
Pubmed

Muc5b is required for airway defence.

MUC5B MUC5AC

1.79e-06247224317696
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5B MUC5AC

1.79e-06247227845589
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5B MUC5AC

1.79e-06247222391959
Pubmed

C-Mannosylation of MUC5AC and MUC5B Cys subdomains.

MUC5B MUC5AC

1.79e-06247214718370
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5B MUC5AC

1.79e-06247235776514
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5B MUC5AC

1.79e-06247227435107
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5B MUC5AC

1.79e-06247224327612
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5B MUC5AC

1.79e-06247226871672
Pubmed

Mucin production during prenatal and postnatal murine lung development.

MUC5B MUC5AC

1.79e-06247221653907
Pubmed

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

MUC5B MUC5AC

1.79e-06247236427316
Pubmed

Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.

MUC5B MUC5AC

1.79e-06247232348677
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5B MUC5AC

1.79e-06247211587997
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5B MUC5AC

1.79e-06247228607090
Pubmed

Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.

MUC5B MUC5AC

1.79e-06247224332705
Pubmed

Interleukin-29 regulates T follicular helper cells by repressing BCL6 in rheumatoid arthritis patients.

BCL6 IFNL1

1.79e-06247232468318
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5B MUC5AC

1.79e-06247234656442
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

AGAP5 AGAP9 NRCAM AGAP4 AGAP6 KCTD16

2.14e-0628147628706196
Pubmed

Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.

MUC5B MUC5AC

5.36e-06347227776277
Pubmed

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.

MUC5B MUC5AC

5.36e-06347234158522
Pubmed

Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.

MUC5B MUC5AC

5.36e-06347229604272
Pubmed

High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.

MUC5B MUC5AC

5.36e-06347229286856
Pubmed

IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.

MUC5B MUC5AC

5.36e-06347219596978
Pubmed

Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.

MUC5B MUC5AC

5.36e-06347236675209
Pubmed

Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.

MUC5B MUC5AC

5.36e-06347219556605
Pubmed

Aquaporin 5 expression increases mucin production in lung adenocarcinoma.

MUC5B MUC5AC

5.36e-06347221455588
Pubmed

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.

MUC5B MUC5AC

5.36e-06347229802623
Pubmed

Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.

MUC5B MUC5AC

5.36e-06347220422702
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC5AC

5.36e-06347219718741
Pubmed

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.

MUC5B MUC5AC

1.07e-05447231582416
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC5AC

1.07e-05447223807779
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC5B MUC5AC

1.07e-05447225638393
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC5AC

1.07e-05447217471237
Pubmed

MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium.

MUC5B MUC5AC

1.07e-05447221097527
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC5B MUC5AC

1.07e-05447222269464
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC5AC

1.07e-05447214984930
Pubmed

TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.

MUC5B MUC5AC

1.07e-05447223249391
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC5AC

1.07e-05447212676567
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC5AC

1.07e-05447229869461
Pubmed

Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.

MUC5B MUC5AC

1.07e-05447218258655
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

KATNIP AGAP5 AGAP9 AGAP4 AGAP6

1.14e-0521847533378226
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC5B MUC5AC

1.78e-05547211062147
Pubmed

Differential expression of MUC genes in endometrial and cervical tissues and tumors.

MUC5B MUC5AC

1.78e-05547216188033
Pubmed

Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.

AGAP5 AGAP9 AGAP4 AGAP6

1.88e-0511647430652415
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC5B MUC5AC

2.67e-05647219110483
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

PRAMEF33 AGAP5 PRAMEF17 AGAP9 GAS2L2 AGAP4 AGAP6 SH3PXD2A TTLL11

3.68e-05124247930973865
Pubmed

Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine.

MUC5AC TET3

4.98e-05847236539616
Pubmed

Physical mapping of the Tec and Gabrb1 loci reveals that the Wsh mutation on mouse chromosome 5 is associated with an inversion.

RFC1 TEC

6.40e-0594728589683
Pubmed

Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study.

MUC5B MUC5AC

9.75e-051147224429156
Pubmed

Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways.

MUC5B MUC5AC

1.61e-041447222797898
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC5B MUC5AC

2.70e-041847218834073
Pubmed

Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans.

BCL6 HMCN1

2.70e-041847223534349
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

ACSL3 AGAP5 AGAP9 AGAP4 AGAP6

2.82e-0443047532581705
Pubmed

Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.

PRAMEF33 PRAMEF17

3.34e-042047226694250
Pubmed

Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.

PRAMEF33 PRAMEF17

4.06e-042247231729367
Pubmed

Preferred SH3 domain partners of ADAM metalloproteases include shared and ADAM-specific SH3 interactions.

TEC SH3PXD2A

4.84e-042447225825872
Pubmed

MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.

PRAMEF33 PRAMEF17

5.26e-042547237451217
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF33 PRAMEF17

6.61e-042847225089626
Pubmed

Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.

PRAMEF33 PRAMEF17

7.59e-043047238786026
Pubmed

E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.

RB1CC1 TLL1 TTLL11

8.18e-0413547329859926
Pubmed

Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation.

SOX4 MUC5B

1.03e-033547218374910
Pubmed

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.

PRAMEF33 PRAMEF17

1.03e-033547219389355
Cytoband10q11.22

AGAP9 AGAP4

8.20e-044147210q11.22
CytobandEnsembl 112 genes in cytogenetic band chr10q11

AGAP9 AGAP4 AGAP6

9.60e-04188473chr10q11
Cytoband1p36.21

PRAMEF33 PRAMEF17

1.93e-03634721p36.21
Cytoband19q13.33

SIGLEC16 ZNF114

5.33e-0310647219q13.33
Cytoband11p15.5

MUC5B MUC5AC

6.57e-0311847211p15.5
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP5 AGAP9 AGAP4 AGAP6

1.08e-08172841291
GeneFamilyArfGAPs

AGAP5 AGAP9 AGAP4 AGAP6

1.83e-0733284395
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AGAP5 AGAP9 TEC AGAP4 AGAP6

1.45e-05206285682
GeneFamilyCD molecules|Mucins

MUC5B MUC5AC

4.77e-0421282648
GeneFamilyAnkyrin repeat domain containing

AGAP5 AGAP9 AGAP4 AGAP6

4.98e-04242284403
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SIGLEC16 HMCN1 NRCAM

1.93e-03161283593
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CFHR5 CSMD2

3.50e-03572821179
CoexpressionTHEODOROU_MAMMARY_TUMORIGENESIS

AGAP5 AGAP9 AGAP4 AGAP6

5.25e-0737464MM1121
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN

AGAP5 AGAP9 AGAP4 AGAP6

1.07e-0644464MM485
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SOX4 BEST3 BNIP5 APLP2 NRCAM KIF26B

5.86e-08196476ef650ff106a76c1e926e13c7f002fbc452cc48ae
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BEST3 MUC5B SGMS2 MUC5AC KIF26B

8.71e-0716647560060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BEST3 MUC5B SGMS2 MUC5AC KIF26B

8.71e-07166475ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BEST3 MUC5B SGMS2 MUC5AC KIF26B

8.71e-071664754586d6725403f879fc96f67be579022587ce1906
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B BCL6 MUC5AC SH3PXD2A

1.26e-061794756e965e424eebef50f0202cff75f458be395cfca1
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

SOX4 CSMD2 KIF26B TLL1 KCTD16

2.18e-062004754fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

SOX4 CSMD2 KIF26B TLL1 KCTD16

2.18e-06200475f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

SOX4 CSMD2 KIF26B TLL1 KCTD16

2.18e-06200475cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

SOX4 CSMD2 KIF26B TLL1 KCTD16

2.18e-06200475310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

SOX4 CSMD2 KIF26B TLL1 KCTD16

2.18e-06200475c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

SOX4 CSMD2 KIF26B TLL1 KCTD16

2.18e-06200475961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_mature|E16.5-samps / Age Group, Lineage, Cell class and subclass

BNIP5 MAP7D3 NRCAM A3GALT2

6.64e-06115474c3f6efb90d5ee01af831f65e240505faa6a71dc0
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B HMCN1 KCTD19 TLL1

2.44e-05160474c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B HMCN1 KCTD19 TLL1

2.44e-0516047425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEC MPIG6B TTLL11 A3GALT2

2.50e-0516147452556b89808e551540f33a13f57417a6696c2438
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEC MPIG6B TTLL11 A3GALT2

2.50e-0516147454f156cf2bd5a6ba9a78ec4e3ee28b89998aec2e
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEC MPIG6B TTLL11 A3GALT2

2.50e-05161474242891be849a4398fe8bea44875ae1ba57950944
ToppCelldroplet-Heart-HEART-1m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSL3 NRCAM KIF26B TLL1

3.31e-051734749dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BEST3 CSMD2 NRCAM KIF26B

3.39e-05174474b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BEST3 CSMD2 NRCAM KIF26B

3.39e-05174474cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BEST3 CSMD2 NRCAM KIF26B

3.39e-0517447471730503be3d9c839c4c9e950145e2101d682a1c
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

BEST3 CSMD2 NRCAM KIF26B

3.39e-05174474ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B HMCN1 NRCAM KIF26B

4.21e-05184474ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B HMCN1 NRCAM KIF26B

4.21e-051844742cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B HMCN1 NRCAM KIF26B

4.21e-051844742b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX4 KIF26B TLL1 KCTD16

4.87e-051914741cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell(7)_Epithelial_cells-(7)_Epithelial-G_(Club-Clara_cells)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

SOX4 MUC5B MUC5AC TLL1

4.97e-05192474c7c232545fad8ad327ab94bd0def8dc5daacd03d
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SOX4 MUC5B MUC5AC TLL1

5.07e-051934748ede7038a222c7e7ecaf7e86520823cf606cbee7
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SOX4 MUC5B MUC5AC TLL1

5.07e-051934740e7d7adfaa7191e34038fcda6677561ae13934eb
ToppCell(07)_Brush|World / shred by cell type and Timepoint

BNIP5 NRCAM TTLL11 A3GALT2

5.07e-051934749af9d22a130ff97a9c37142a65e841b056d08640
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

HMCN1 CSMD2 KIF26B KCTD16

5.17e-0519447403a269f75a481ea54aea8e6444605db8d6df493d
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SOX4 BEST3 BNIP5 NRCAM

5.38e-0519647472b6a68ee760599ea86cd2d712bfd17b7b4ee417
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX4 CCDC60 BNIP5 MUC5B

5.38e-05196474847b3377f463bfded046eec63cc1b547f3dc33c1
ToppCellAT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

SOX4 BNIP5 MUC5B HMCN1

5.49e-051974745e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

HMCN1 CSMD2 NRCAM KIF26B

5.49e-05197474f1c8936986123a3151140c374fcd62d6705c530b
ToppCellNS-critical-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SOX4 MUC5B MUC5AC SH3PXD2A

5.49e-05197474a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

SOX4 HMCN1 KIF26B SH3PXD2A

5.49e-05197474f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellnormal_Lung-Epithelial_cells-Club|Epithelial_cells / Location, Cell class and cell subclass

SOX4 MUC5B MUC5AC TLL1

5.60e-05198474a9d0109ca05eb3e9c588f9677ec471dd5c092a75
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B MUC5AC KIF26B TLL1

5.60e-05198474af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

AGAP4 AGAP6 TEC

1.96e-04107473410b37beffaf637a2a64c9d0ce7baf81f4bc667c
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

AGAP4 AGAP6 TEC

1.96e-041074735bae4b3aede9bcbf7e88414e3453973cc8b0c3e7
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-mesenchymal_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PRAMEF17 MPIG6B TTLL11

2.82e-04121473176de42c088988fe1a7838f96add26ee8a30e543
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MAP7D3 MUC5AC KCTD16

4.06e-0413747325b5370b63644351efddb8749ef174beca0581cd
ToppCellClub_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

SOX4 MUC5B MUC5AC

4.99e-041474735a824c89e4d045af465d7333275f8191fb29b041
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX4 BNIP5 KIF25-AS1

5.60e-04153473499670e716fc85ce76630fc813cec86f8419f2a1
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B KCTD19

5.60e-041534733240d4d690335ba22317b1f3d33f9ea069e93838
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B KCTD19

5.60e-04153473edf5d026e8e4c685b7c369d70894741bb2cd568e
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B TEC

5.71e-04154473ec56b7fb88e39041416c384f371c767f3b4e92fa
ToppCell390C-Lymphocytic-NK_cells-NK_cell_E|390C / Donor, Lineage, Cell class and subclass (all cells)

TET3 TTLL11 IFNL1

5.82e-0415547398d8432739965dd1ab77c899cb6321f7f05eaa46
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B GAS2L2 MUC5AC

6.04e-04157473c43f2e1ea53b375a7432f17f87cfef3b2261003d
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Club|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

MUC5B PPP1R14D MUC5AC

6.15e-0415847303281e87780e3bacd089903383c016d03c373bf7
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BNIP5 NRCAM SH3PXD2A

6.27e-04159473c9e093d7c1dca83f6546adaf3d874929e2cea612
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNIP5 MUC5B MUC5AC

6.27e-0415947360b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 ACSL3 KIF26B

6.38e-04160473af84da18c85037f49f55e8958f00f12140226982
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 ACSL3 KIF26B

6.38e-04160473f7ca98beaa24f9674d503588eb15d341c4135d77
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 ACSL3 KIF26B

6.38e-04160473a76ad44b5f25f59d6b9333fb45f8bb96196a3090
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC5B PPP1R14D TLL1

6.50e-041614732d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BEST3 APLP2 CSMD2

6.61e-041624739522af31f6b2f3cb81b6b84bd08353eea504d1d6
ToppCell3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BEST3 APLP2 CSMD2

6.61e-041624739a18286e361e1dd18e6f943ce27db58b199fb6e4
ToppCell3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BEST3 APLP2 CSMD2

6.61e-0416247340265af9b36fd144a8577b8dacccd4fc0888a593
ToppCell3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BEST3 APLP2 CSMD2

6.61e-041624733395e4dffdb9304d157c325e1fc0f12b433c7bd3
ToppCellILEUM-non-inflamed-(3)_pDC|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SOX4 TMEM53 MPIG6B

6.73e-04163473bc5411702badab39143905aa51676b4bbfad2041
ToppCellAdult-Epithelial-lung_goblet_cell-D175|Adult / Lineage, Cell type, age group and donor

MUC5B MUC5AC KIF26B

6.85e-041644736e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B MUC5AC

6.85e-0416447376b0ac220b7ca22fbea28a507f01f96ae9f53932
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B MUC5AC

6.85e-04164473911081739174ec68bc0893c804e4276b206bea7d
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B MUC5AC

6.85e-04164473c5bfae7e9497185548c243d6f9ebadbcef48ba7f
ToppCellClub-club-12|World / Class top

MUC5B PPP1R14D MUC5AC

6.98e-041654739b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCellmoderate-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SOX4 PPP1R14D NRCAM

7.10e-04166473c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCellAdult-Epithelial-lung_goblet_cell-D122|Adult / Lineage, Cell type, age group and donor

MUC5B MUC5AC TLL1

7.22e-041674736efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell390C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SOX4 TET3 TTLL11

7.22e-041674736c2dade24a88af04b2c90a7e4f8dd7ccea9e94d1
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B KCTD19

7.22e-04167473d1a13d6ada572d8ddb2da95e6e122d2b705fad7f
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APLP2 HMCN1 KIF26B

7.35e-04168473e40a3f85be7e9bb23bfbc1f9cb5e5fc54bb43863
ToppCellControl-Epithelial_alveolar-Mes-like-AT1_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BCL6 NRCAM ZNF114

7.35e-0416847349180994311b3f4f9ec338b1d35d8edd7422e3c9
ToppCellControl-Epithelial_alveolar-Mes-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BCL6 NRCAM ZNF114

7.35e-041684733c2ce9cfaca8ceab9b29f918ab46afc69eba3330
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APLP2 HMCN1 KIF26B

7.35e-04168473b1d6c35a5ae69c8638afd68c2be5bc9ce6fd2659
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B MUC5AC

7.74e-04171473eddc5e05003382603ee49f74b9e2242a43021096
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX4 BNIP5 MUC5B

7.74e-0417147348125d825ca2d7ef34564250f5b47d2a579e03c9
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 BEST3 PPP1R14D

7.74e-04171473d5960b40ad5b87aaa00c93a6b31cdf41cc4f1375
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 BEST3 PPP1R14D

7.74e-04171473fd59ac4a39748840b2ee1c930ea475433ff61485
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HMCN1 NRCAM SH3PXD2A

7.74e-04171473121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 BEST3 PPP1R14D

7.74e-04171473d382430e5cdd0f2aac4fc093d8fe8d66efb4629b
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 BEST3 PPP1R14D

7.74e-041714734347e6f62c04ea43299893ad4b79719049009a56
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B AGAP4

7.87e-041724735401ac7739f95fb8681cfb4747ab6e447a3c2ae8
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B AGAP4

7.87e-04172473b3da7f488d191214d7bb74fbac189fe8c29ee6cd
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MTBP AGAP9 HMCN1

7.87e-04172473c3a99828838af3b85c8c885d69cc8018f55ced50
ToppCellPND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEC MPIG6B TTLL11

7.87e-04172473e39ea2f4edbf36ebf9604fa6f9349081859c596c
ToppCellPND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEC MPIG6B TTLL11

7.87e-04172473bcc50bed47465daa953ba91f17d1ee4c947ab461
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TEC MPIG6B KCTD19

7.87e-0417247337ff83f53e99df62691d078ca6801b2c0ec2b123
ToppCellPND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEC MPIG6B TTLL11

7.87e-04172473875ea290840e835952623b905eb610f3c71456d2
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B AGAP4

7.87e-0417247374dd4a7acb2cf857fed20219e4d7dc1adfbaa398
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC5B MUC5AC TLL1

8.00e-04173473464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCellPND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEC MPIG6B A3GALT2

8.13e-04174473a3f4981b10afa9d41a1c66c7f98522a8a534f82b
ToppCellfacs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APLP2 AMER3 HMCN1

8.13e-0417447342dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCellPND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEC MPIG6B A3GALT2

8.13e-041744736cc108dde4b3f98a78a6040280f0d5e4aaa5bd75
ToppCellPND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEC MPIG6B A3GALT2

8.13e-041744734b8bc5568e36031c8ecf001bb646809038c23919
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

MUC5B MUC5AC TLL1

8.13e-041744737d2f802f493f19a068e097b2909a9000e2160266
ToppCellfacs-Heart-RA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APLP2 AMER3 HMCN1

8.13e-04174473f04edf2ca6788875c9918611e416fb739924382e
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 MUC5B MUC5AC

8.55e-04177473a235ff4f37a7622216526191efc4832fb8ed6957
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC5B MUC5AC TLL1

8.55e-04177473779ba86f53650772755b52460be03f18bb204e55
ToppCellE16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEC MPIG6B TTLL11

8.55e-0417747384591e28482ab62a5ef41e61043eb64912766356
Diseasecerebral palsy (implicated_via_orthology)

AGAP5 AGAP9 AGAP4 AGAP6

8.97e-1010444DOID:1969 (implicated_via_orthology)
Diseasetyrosine-protein kinase TEC measurement

TEC TEC

1.30e-054442EFO_0020830
Diseasepulmonary fibrosis

MUC5B MUC5AC

1.19e-0411442EFO_0009448
Diseasecystathionine measurement

TEC TEC

3.66e-0419442EFO_0010474
Diseaseanorectal malformation

MUC5B CSMD2

3.66e-0419442MONDO_0019938
Diseaseasthma (is_marker_for)

MUC5B MUC5AC IFNL1

8.86e-04126443DOID:2841 (is_marker_for)
DiseaseCOVID-19 symptoms measurement

MUC5B MUC5AC

1.25e-0335442EFO_0600019
Diseasemyositis

TEC TEC

1.55e-0339442EFO_0000783
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

TEC TET3 TEC

2.09e-03170443EFO_0000685, EFO_0007791, EFO_0007837
Diseaseidiopathic pulmonary fibrosis

MUC5B MUC5AC

3.29e-0357442EFO_0000768
Diseasepancreatic ductal carcinoma (is_marker_for)

MUC5B MUC5AC

3.76e-0361442DOID:3587 (is_marker_for)
Diseasecystic fibrosis (is_marker_for)

MUC5B MUC5AC

3.88e-0362442DOID:1485 (is_marker_for)
Diseasecholangiocarcinoma (is_marker_for)

MUC5B MUC5AC

4.13e-0364442DOID:4947 (is_marker_for)
Diseaseinterstitial lung disease

MUC5B MUC5AC

4.52e-0367442EFO_0004244
Diseaserheumatoid arthritis

TEC TET3 SH3PXD2A TEC

4.91e-03462444EFO_0000685
Diseaseurinary bladder cancer (is_implicated_in)

SOX4 MUC5B

5.77e-0376442DOID:11054 (is_implicated_in)
Diseaseresponse to selective serotonin reuptake inhibitor

CSMD2 KIF26B

6.69e-0382442EFO_0005658

Protein segments in the cluster

PeptideGeneStartEntry
PCPTCGSWPSEKVDF

PRAMEF33

456

A0A0G2JMD5
ASPTWKKSCFPEGSP

BEST3

446

Q8N1M1
TSGKNKAPVPSTWPC

AMER3

626

Q8N944
KVPGKWPSLATSACT

AGAP4

316

Q96P64
PGKWPSLATSACAPI

AGAP9

386

Q5VTM2
TCKADGSWTGKPPIC

CSMD2

3231

Q7Z408
KVPGKWPSLATSACT

AGAP6

316

Q5VW22
TCWNPKDPGGSKSTI

CCDC60

181

Q8IWA6
APKDPCTANPFRKSW

MUC5B

1066

Q9HC84
WGSHPESPPKKKCTT

KCTD19

601

Q17RG1
QTGKWEPDPTGTKSC

APLP2

66

Q06481
DSWPPSFCTQKPRKF

RB1CC1

556

Q8TDY2
PCPSCGSWPSEKVDF

PRAMEF17

456

Q5VTA0
SGPSFWLPQEKKCKP

LEXM

311

Q3ZCV2
CPPSSLLPADRKWGF

KCTD16

151

Q68DU8
IQCEAKGKPPPSFSW

NRCAM

66

Q92823
GKKDSSPWTCPFHPP

KATNIP

536

O60303
CSPTKPAAPFSPESW

KIF26B

26

Q2KJY2
FLSSGGPSPLKWSVC

C9orf131

211

Q5VYM1
APKDPCTANPFRKSW

MUC5AC

1076

P98088
AAKEVSAPKAPGSPW

KIF25-AS1

71

Q9Y6Z4
LCTWKKDTGSPPASE

ITFG2

211

Q969R8
PCKASGNPKPSVIWS

HMCN1

1001

Q96RW7
AWPPKKSSFLPLCVS

BNIP5

321

P0C671
STEDHSKWCVSPKGP

DNASE2

291

O00115
EAWKAAPTGSPKPAV

GAS2L2

671

Q8NHY3
LKLKNWSCSSPVFPG

IFNL1

61

Q8IU54
HKPAKVLSPEFCWSP

A3GALT2

301

U3KPV4
SPPAKSPTDPKACNW

BCL6

361

P41182
GWSPTPKCLRMCSFP

CFHR5

76

Q9BXR6
KWSSSPENACGLPSP

MAP7D3

496

Q8IWC1
GAPYLKTCKAPPSEW

C3orf56

176

Q8N813
KTCKAPPSEWASRFG

C3orf56

181

Q8N813
PACSVGGIPGSKKWF

MTBP

66

Q96DY7
SPSPDGENPCKKVHW

PPP1R14D

11

Q9NXH3
STGGKADDPSWCKTP

SOX4

41

Q06945
TSPNWPDKYPSRKEC

TLL1

786

O43897
SSSGAKFPVKWCPPE

TEC

521

P42680
ISSWGGKPSPFSKLD

RFC1

1041

P35251
WAPSFPACKGLSKGR

MPIG6B

46

O95866
PLSWPPGCFKSSCKK

SGMS2

336

Q8NHU3
TVDGKPPTWSEFPKG

ACSL3

236

O95573
PGKWPSLATSACAPI

AGAP5

341

A6NIR3
APGPPASSAAVWKKS

ZNF414

276

Q96IQ9
SWKPTFIVKPDGGCQ

TTLL11

331

Q8NHH1
PCPTKKEWEGPATSY

SH3PXD2A

831

Q5TCZ1
PCWSQKNSPSPGGKE

TMEM53

16

Q6P2H8
KPWSPCKFGNSTSAL

TET3

1511

O43151
FKKCPAPSFSWTGAA

SIGLEC16

171

A6NMB1
DWATPCKTKDATPQP

ZNF114

46

Q8NC26