Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytidine deaminase activity	APOBEC3D APOBEC3C APOBEC3F	2.14e-05	13	86	3	GO:0004126
GeneOntologyBiologicalProcess	clearance of foreign intracellular DNA	APOBEC3D APOBEC3C APOBEC3F	1.54e-06	6	89	3	GO:0044355
GeneOntologyBiologicalProcess	clearance of foreign intracellular nucleic acids	APOBEC3D APOBEC3C APOBEC3F	1.54e-06	6	89	3	GO:0099046
GeneOntologyBiologicalProcess	DNA cytosine deamination	APOBEC3D APOBEC3C APOBEC3F	9.12e-06	10	89	3	GO:0070383
GeneOntologyBiologicalProcess	cytidine to uridine editing	APOBEC3D APOBEC3C APOBEC3F	1.66e-05	12	89	3	GO:0016554
GeneOntologyBiologicalProcess	cytidine catabolic process	APOBEC3D APOBEC3C APOBEC3F	2.73e-05	14	89	3	GO:0006216
GeneOntologyBiologicalProcess	DNA deamination	APOBEC3D APOBEC3C APOBEC3F	2.73e-05	14	89	3	GO:0045006
GeneOntologyBiologicalProcess	cytidine metabolic process	APOBEC3D APOBEC3C APOBEC3F	2.73e-05	14	89	3	GO:0046087
GeneOntologyBiologicalProcess	cytidine deamination	APOBEC3D APOBEC3C APOBEC3F	2.73e-05	14	89	3	GO:0009972
GeneOntologyBiologicalProcess	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3D APOBEC3C APOBEC3F	4.18e-05	16	89	3	GO:0045869
GeneOntologyBiologicalProcess	pyrimidine ribonucleoside metabolic process	APOBEC3D APOBEC3C APOBEC3F	4.18e-05	16	89	3	GO:0046131
GeneOntologyBiologicalProcess	pyrimidine ribonucleoside catabolic process	APOBEC3D APOBEC3C APOBEC3F	4.18e-05	16	89	3	GO:0046133
GeneOntologyBiologicalProcess	ribonucleoside metabolic process	APOBEC3D APOBEC3C NT5C1B APOBEC3F	5.45e-05	48	89	4	GO:0009119
GeneOntologyBiologicalProcess	pyrimidine nucleoside catabolic process	APOBEC3D APOBEC3C APOBEC3F	6.05e-05	18	89	3	GO:0046135
GeneOntologyBiologicalProcess	regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3D APOBEC3C APOBEC3F	7.16e-05	19	89	3	GO:0045091
GeneOntologyBiologicalProcess	base conversion or substitution editing	APOBEC3D APOBEC3C APOBEC3F	7.16e-05	19	89	3	GO:0016553
GeneOntologyBiologicalProcess	single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3D APOBEC3C APOBEC3F	8.39e-05	20	89	3	GO:0039692
GeneOntologyBiologicalProcess	ribonucleoside catabolic process	APOBEC3D APOBEC3C APOBEC3F	1.88e-04	26	89	3	GO:0042454
GeneOntologyBiologicalProcess	pyrimidine nucleoside metabolic process	APOBEC3D APOBEC3C APOBEC3F	2.11e-04	27	89	3	GO:0006213
GeneOntologyBiologicalProcess	nucleoside metabolic process	APOBEC3D APOBEC3C NT5C1B APOBEC3F	2.14e-04	68	89	4	GO:0009116
GeneOntologyBiologicalProcess	inhibitory synapse assembly	GABRE GABRG3 CNTNAP2	2.90e-04	30	89	3	GO:1904862
GeneOntologyBiologicalProcess	DNA modification	APOBEC3D APOBEC3C APOBEC3F	3.20e-04	31	89	3	GO:0006304
GeneOntologyBiologicalProcess	viral RNA genome replication	APOBEC3D APOBEC3C APOBEC3F	3.52e-04	32	89	3	GO:0039694
GeneOntologyBiologicalProcess	nucleoside catabolic process	APOBEC3D APOBEC3C APOBEC3F	3.52e-04	32	89	3	GO:0009164
GeneOntologyBiologicalProcess	nucleobase-containing small molecule catabolic process	APOBEC3D APOBEC3C APOBEC3F	5.43e-04	37	89	3	GO:0034656
Domain	APOBEC_N	APOBEC3D APOBEC3C APOBEC3F	1.88e-05	12	84	3	PF08210
Domain	APOBEC_N	APOBEC3D APOBEC3C APOBEC3F	1.88e-05	12	84	3	IPR013158
Domain	APOBEC/CMP_deaminase_Zn-bd	APOBEC3D APOBEC3C APOBEC3F	3.08e-05	14	84	3	IPR016192
Domain	Cytidine_deaminase-like	APOBEC3D APOBEC3C APOBEC3F	5.70e-05	17	84	3	IPR016193
Domain	CYT_DCMP_DEAMINASES_1	APOBEC3D APOBEC3C APOBEC3F	5.70e-05	17	84	3	PS00903
Domain	CMP_dCMP_Zn-bd	APOBEC3D APOBEC3C APOBEC3F	5.70e-05	17	84	3	IPR002125
Domain	MBT	SCML2 L3MBTL3	7.05e-04	9	84	2	SM00561
Domain	MBT	SCML2 L3MBTL3	7.05e-04	9	84	2	PS51079
Domain	MBT	SCML2 L3MBTL3	8.79e-04	10	84	2	PF02820
Domain	Mbt	SCML2 L3MBTL3	8.79e-04	10	84	2	IPR004092
Domain	CarboxyPept_regulatory_dom	AEBP1 CPD	1.51e-03	13	84	2	IPR014766
Domain	-	AEBP1 CPD	1.51e-03	13	84	2	2.60.40.1120
Domain	CYT_DCMP_DEAMINASES_2	APOBEC3C APOBEC3F	2.02e-03	15	84	2	PS51747
Domain	GPCR_2_secretin-like	FZD7 ADGRF5 ADGRA3	2.50e-03	60	84	3	IPR000832
Domain	GPCR_2-like	FZD7 ADGRF5 ADGRA3	2.50e-03	60	84	3	IPR017981
Domain	CarboxyPept-like_regulatory	AEBP1 CPD	2.60e-03	17	84	2	IPR008969
Domain	G_PROTEIN_RECEP_F2_4	FZD7 ADGRF5 ADGRA3	2.62e-03	61	84	3	PS50261
Domain	Zn_pept	AEBP1 CPD	2.92e-03	18	84	2	SM00631
Domain	CARBOXYPEPT_ZN_1	AEBP1 CPD	3.60e-03	20	84	2	PS00132
Domain	FA58C	AEBP1 CNTNAP2	3.97e-03	21	84	2	SM00231
Domain	FA58C_3	AEBP1 CNTNAP2	3.97e-03	21	84	2	PS50022
Domain	FA58C_1	AEBP1 CNTNAP2	3.97e-03	21	84	2	PS01285
Domain	FA58C_2	AEBP1 CNTNAP2	3.97e-03	21	84	2	PS01286
Domain	Peptidase_M14	AEBP1 CPD	4.76e-03	23	84	2	PF00246
Domain	GABAA/Glycine_rcpt	GABRE GABRG3	4.76e-03	23	84	2	IPR006028
Domain	Peptidase_M14	AEBP1 CPD	4.76e-03	23	84	2	IPR000834
Pubmed	The APOBEC3C crystal structure and the interface for HIV-1 Vif binding.	APOBEC3D APOBEC3C APOBEC3F	1.68e-08	3	90	3	23001005
Pubmed	Identification of specific determinants of human APOBEC3F, APOBEC3C, and APOBEC3DE and African green monkey APOBEC3F that interact with HIV-1 Vif.	APOBEC3D APOBEC3C APOBEC3F	1.68e-08	3	90	3	20943965
Pubmed	Distinct determinants in HIV-1 Vif and human APOBEC3 proteins are required for the suppression of diverse host anti-viral proteins.	APOBEC3D APOBEC3C APOBEC3F	6.69e-08	4	90	3	19088851
Pubmed	A patch of positively charged amino acids surrounding the human immunodeficiency virus type 1 Vif SLVx4Yx9Y motif influences its interaction with APOBEC3G.	APOBEC3D APOBEC3C APOBEC3F	6.69e-08	4	90	3	19535450
Pubmed	Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: ex vivo effects and in vivo "traces" on the murine IAPE and human HERV-K elements.	APOBEC3D APOBEC3C APOBEC3F	6.69e-08	4	90	3	18702815
Pubmed	Species-specific restriction of apobec3-mediated hypermutation.	APOBEC3D APOBEC3C APOBEC3F	6.69e-08	4	90	3	18032489
Pubmed	HIV-1 Vif, APOBEC, and intrinsic immunity.	APOBEC3D APOBEC3C APOBEC3F	1.67e-07	5	90	3	18577210
Pubmed	AID and APOBECs span the gap between innate and adaptive immunity.	APOBEC3D APOBEC3C APOBEC3F	1.67e-07	5	90	3	25352838
Pubmed	The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements.	APOBEC3D APOBEC3C APOBEC3F	1.67e-07	5	90	3	18304004
Pubmed	Host restriction of HIV-1 by APOBEC3 and viral evasion through Vif.	APOBEC3D APOBEC3C APOBEC3F	1.67e-07	5	90	3	20012521
Pubmed	A computational analysis of the structural determinants of APOBEC3's catalytic activity and vulnerability to HIV-1 Vif.	APOBEC3D APOBEC3C APOBEC3F	1.67e-07	5	90	3	25461536
Pubmed	Structure-guided analysis of the human APOBEC3-HIV restrictome.	APOBEC3D APOBEC3C APOBEC3F	3.33e-07	6	90	3	24657093
Pubmed	Vif proteins of human and simian immunodeficiency viruses require cellular CBFβ to degrade APOBEC3 restriction factors.	APOBEC3D APOBEC3C APOBEC3F	3.33e-07	6	90	3	22205746
Pubmed	Retroelements versus APOBEC3 family members: No great escape from the magnificent seven.	APOBEC3D APOBEC3C APOBEC3F	3.33e-07	6	90	3	22912627
Pubmed	APOBEC3 proteins mediate the clearance of foreign DNA from human cells.	APOBEC3D APOBEC3C APOBEC3F	5.82e-07	7	90	3	20062055
Pubmed	APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons.	APOBEC3D APOBEC3C APOBEC3F	5.82e-07	7	90	3	16527742
Pubmed	An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22.	APOBEC3D APOBEC3C APOBEC3F	5.82e-07	7	90	3	11863358
Pubmed	Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1.	APOBEC3D APOBEC3C APOBEC3F	5.82e-07	7	90	3	21835787
Pubmed	APOBEC3 deaminases induce hypermutation in human papillomavirus 16 DNA upon beta interferon stimulation.	APOBEC3D APOBEC3C APOBEC3F	9.30e-07	8	90	3	24227842
Pubmed	The assembly of Vif ubiquitin E3 ligase for APOBEC3 degradation.	APOBEC3D APOBEC3C APOBEC3F	1.39e-06	9	90	3	25408426
Pubmed	Introduction to thematic minireview series: Understanding human immunodeficiency virus-host interactions at the biochemical level.	APOBEC3D APOBEC3C APOBEC3F	1.98e-06	10	90	3	23043103
Pubmed	Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS.	APOBEC3D APOBEC3C APOBEC3F	1.98e-06	10	90	3	20174454
Pubmed	HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies.	APOBEC3D APOBEC3C APOBEC3F	2.72e-06	11	90	3	22915799
Pubmed	Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business.	APOBEC3D APOBEC3C APOBEC3F	2.72e-06	11	90	3	12683974
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	FLT4 MAN2A1 CP ADGRF5 ITGA2B ECM1 ITGB1	4.91e-06	257	90	7	16335952
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZSWIM8 KIAA0825 CNTNAP2 ADGRF5 DENND3	6.43e-06	100	90	5	10048485
Pubmed	Deubiquitinase USP9X stabilizes RNA m6A demethylase ALKBH5 and promotes acute myeloid leukemia cell survival.	USP9X ALKBH5	6.62e-06	2	90	2	37454738
Pubmed	Stimulation of beta 1 integrin induces tyrosine phosphorylation of vascular endothelial growth factor receptor-3 and modulates cell migration.	FLT4 ITGB1	6.62e-06	2	90	2	11553610
Pubmed	Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.	USP9X USP9Y	6.62e-06	2	90	2	12925892
Pubmed	ALKBH5 activates FAK signaling through m6A demethylation in ITGB1 mRNA and enhances tumor-associated lymphangiogenesis and lymph node metastasis in ovarian cancer.	ITGB1 ALKBH5	6.62e-06	2	90	2	36632222
Pubmed	Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.	USP9X USP9Y	6.62e-06	2	90	2	12895410
Pubmed	Vif Proteins from Diverse Human Immunodeficiency Virus/Simian Immunodeficiency Virus Lineages Have Distinct Binding Sites in A3C.	APOBEC3C APOBEC3F	6.62e-06	2	90	2	27581978
Pubmed	The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.	USP9X USP9Y	6.62e-06	2	90	2	8922996
Pubmed	Sequence and evolution of the human germline V lambda repertoire.	IGLV1-47 IGLV1-44 IGLV1-36 IGLV5-39	8.13e-06	49	90	4	8951372
Pubmed	Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all.	APOBEC3D APOBEC3C APOBEC3F	1.11e-05	17	90	3	24189052
Pubmed	Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics.	APOBEC3D APOBEC3C APOBEC3F	1.33e-05	18	90	3	20096141
Pubmed	Murine Leukemia Virus P50 Protein Counteracts APOBEC3 by Blocking Its Packaging.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	32641479
Pubmed	APOBEC3 deletion increases the risk of breast cancer: a meta-analysis.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	27602762
Pubmed	Small-molecule inhibition of HIV-1 Vif.	APOBEC3C APOBEC3F	1.98e-05	3	90	2	18806783
Pubmed	A novel role for APOBEC3: susceptibility to sexual transmission of murine acquired immunodeficiency virus (mAIDS) is aggravated in APOBEC3 deficient mice.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	22691411
Pubmed	Studies on the restriction of murine leukemia viruses by mouse APOBEC3.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	22666481
Pubmed	APOBEC3 deletion polymorphism is associated with epithelial ovarian cancer risk among Chinese women.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	24577894
Pubmed	Enhancing immunity to HIV through APOBEC.	APOBEC3C APOBEC3F	1.98e-05	3	90	2	18846074
Pubmed	APOBEC3DE Antagonizes Hepatitis B Virus Restriction Factors APOBEC3F and APOBEC3G.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	27289067
Pubmed	APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	16648136
Pubmed	Polymorphism of human platelet alloantigen in Chinese patients with acute myocardial infarction and acute ischemic stroke.	ITGA2B ITGB1	1.98e-05	3	90	2	11776052
Pubmed	Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	23533681
Pubmed	Spontaneous recovery from Friend retrovirus-induced leukemia. Mapping of the Rfv-2 gene in the Q/TL region of mouse MHC.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	1541833
Pubmed	In Vivo Examination of Mouse APOBEC3- and Human APOBEC3A- and APOBEC3G-Mediated Restriction of Parvovirus and Herpesvirus Infection in Mouse Models.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	27356895
Pubmed	IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	23315078
Pubmed	Requirement for Fc effector mechanisms in the APOBEC3/Rfv3-dependent neutralizing antibody response.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	25589647
Pubmed	Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	23671100
Pubmed	Structural perspectives on HIV-1 Vif and APOBEC3 restriction factor interactions.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	31518043
Pubmed	Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection.	FLT4 ITGB1	1.98e-05	3	90	2	15878864
Pubmed	APOBEC3 signature mutations in chronic lymphocytic leukemia.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	24840555
Pubmed	Nuclear import of APOBEC3F-labeled HIV-1 preintegration complexes.	APOBEC3C APOBEC3F	1.98e-05	3	90	2	24248339
Pubmed	Requirement for CD4(+) T cells in the Friend murine retrovirus neutralizing antibody response: evidence for functional T cells in genetic low-recovery mice.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	9765497
Pubmed	Biochemical and biological studies of mouse APOBEC3.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	24453360
Pubmed	APOBEC3 inhibition of mouse mammary tumor virus infection: the role of cytidine deamination versus inhibition of reverse transcription.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	23449789
Pubmed	APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	25330146
Pubmed	APOBEC3-independent interferon-induced viral clearance in hepatitis B virus transgenic mice.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	18434399
Pubmed	HPA-genotyping and antiplatelet antibodies in female blood donors.	ITGA2B ITGB1	1.98e-05	3	90	2	14671618
Pubmed	Induction of APOBEC3 in vivo causes increased restriction of retrovirus infection.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	19153238
Pubmed	Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	18772436
Pubmed	Extracellular matrix regulates endothelial functions through interaction of VEGFR-3 and integrin alpha5beta1.	FLT4 ITGB1	1.98e-05	3	90	2	15389531
Pubmed	Endogenous origins of HIV-1 G-to-A hypermutation and restriction in the nonpermissive T cell line CEM2n.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	22807680
Pubmed	Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	18786991
Pubmed	Anti-Friend virus antibody is associated with recovery from viremia and loss of viral leukemia cell-surface antigens in leukemic mice. Identification of Rfv-3 as a gene locus influencing antibody production.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	286744
Pubmed	Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	24725948
Pubmed	The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	20702647
Pubmed	Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	20980520
Pubmed	Identification of a non-H-2 gene (Rfv-3) influencing recovery from viremia and leukemia induced by Friend virus complex.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	284359
Pubmed	Adaptive evolution of Mus Apobec3 includes retroviral insertion and positive selection at two clusters of residues flanking the substrate groove.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	20617165
Pubmed	Impact of Suboptimal APOBEC3G Neutralization on the Emergence of HIV Drug Resistance in Humanized Mice.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	31801862
Pubmed	The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study.	ITGA2B ITGB1	1.98e-05	3	90	2	20947017
Pubmed	Apobec-mediated retroviral hypermutation in vivo is dependent on mouse strain.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	39208378
Pubmed	Deamination hotspots among APOBEC3 family members are defined by both target site sequence context and ssDNA secondary structure.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	31943071
Pubmed	Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein.	APOBEC3C APOBEC3F	1.98e-05	3	90	2	25724652
Pubmed	Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	20566830
Pubmed	Chromosome mapping of Rfv3, a host resistance gene to Friend murine retrovirus.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	7884913
Pubmed	N-linked glycosylation protects gammaretroviruses against deamination by APOBEC3 proteins.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	25505062
Pubmed	Molecular analysis of γ1, γ3, and α class switch recombination junctions in APOBEC3-deficient mice using high-throughput sequencing.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	31595054
Pubmed	Role of APOBEC3 in genetic diversity among endogenous murine leukemia viruses.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	17967065
Pubmed	Inhibition of xenotropic murine leukemia virus-related virus by APOBEC3 proteins and antiviral drugs.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	20335265
Pubmed	Deaminase-Dead Mouse APOBEC3 Is an In Vivo Retroviral Restriction Factor.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	29593034
Pubmed	Mouse APOBEC3 interferes with autocatalytic cleavage of murine leukemia virus Pr180gag-pol precursor and inhibits Pr65gag processing.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	31830125
Pubmed	Identification of ILK as a critical regulator of VEGFR3 signalling and lymphatic vascular growth.	FLT4 ITGB1	1.98e-05	3	90	2	30518533
Pubmed	Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	21998583
Pubmed	Direct inhibition of human APOBEC3 deaminases by HIV-1 Vif independent of the proteolysis pathway.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	38115583
Pubmed	Arginine methylation of USP9X promotes its interaction with TDRD3 and its anti-apoptotic activities in breast cancer cells.	TDRD3 USP9X	1.98e-05	3	90	2	28101374
Pubmed	E3 ubiquitin ligase RNF180 mediates the ALKBH5/SMARCA5 axis to promote colon inflammation and Th17/Treg imbalance in ulcerative colitis mice.	SMARCA5 ALKBH5	1.98e-05	3	90	2	39060657
Pubmed	Effects of zidovudine on Friend virus complex infection in Rfv-3r/s genotype-containing mice used as a model for HIV infection.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	2157836
Pubmed	Distinctive High Expression of Antiretroviral APOBEC3 Protein in Mouse Germinal Center B Cells.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	35458563
Pubmed	Two genetic determinants acquired late in Mus evolution regulate the inclusion of exon 5, which alters mouse APOBEC3 translation efficiency.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	22275865
Pubmed	Antibody-induced modulation of Friend virus cell surface antigens decreases virus production by persistent erythroleukemia cells: influence of the Rfv-3 gene.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	293683
Pubmed	Enhanced replication and pathogenesis of Moloney murine leukemia virus in mice defective in the murine APOBEC3 gene.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	19150103
Pubmed	Structural Insights into HIV-1 Vif-APOBEC3F Interaction.	APOBEC3C APOBEC3F	1.98e-05	3	90	2	26537685
Pubmed	Initial sequencing and comparative analysis of the mouse genome.	APOBEC3D APOBEC3F	1.98e-05	3	90	2	12466850
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	GPR180 TDRD3 SETX IGF2R MAN2A1 DSP CARS1 CPD APOBEC3C ARIH1 ITGB1 ALKBH5 DYNC1H1	2.90e-05	1297	90	13	33545068
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	GPR180 IGF2R POLR1A USP9X FAM20B NUP133 CPD SARAF PJA1 PTGES3 DYNC1H1	3.22e-05	942	90	11	31073040
Cytoband	22q11.2	IGLV1-50 IGLV1-47 IGLV1-44 IGLV1-36 IGLV5-39	4.13e-06	120	90	5	22q11.2
Cytoband	13q32.1	GPR180 TGDS	4.48e-04	16	90	2	13q32.1
Cytoband	22q13.1	APOBEC3D APOBEC3C APOBEC3F	6.41e-04	85	90	3	22q13.1
GeneFamily	Apolipoprotein B mRNA editing enzyme catalytic subunits	APOBEC3D APOBEC3C APOBEC3F	1.24e-05	12	71	3	406
GeneFamily	Immunoglobulin lambda locus at 22q11.2	IGLV1-50 IGLV1-47 IGLV1-44 IGLV1-36 IGLV5-39	2.60e-05	89	71	5	353
GeneFamily	Sterile alpha motif domain containing\|MBT domain containing	SCML2 L3MBTL3	5.38e-04	9	71	2	1263
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRE GABRG3	2.49e-03	19	71	2	563
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000	TDRD3 SMARCA5 ADAMTSL1 SCML2 DSP USP9X TLL1 YLPM1 NUP133 CPD PTGFR L3MBTL3 ADGRA3	2.35e-05	836	84	13	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	POLR1A PDE8A KIAA0825 TGDS ITGA2B PTGFR	1.28e-06	172	89	6	3b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRE LIMK2 FLT4 PDE8A TLL1 DENND3	1.95e-06	185	89	6	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	IGF2R USP9X REG1A ARIH1 MED13L DYNC1H1	2.14e-06	188	89	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LPIN3 FLT4 ADAMTSL1 AEBP1 TLL1 CP	2.28e-06	190	89	6	e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LPIN3 FLT4 ADAMTSL1 AEBP1 TLL1 CP	2.28e-06	190	89	6	f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCell	Severe-MAIT\|World / Disease group and Cell class	FLT4 TTC39C EFCAB8 SARAF TMEM71 KLRG1	2.28e-06	190	89	6	7a92e0d6a021be23125495927b8571e25c83204a
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LPIN3 FLT4 ADAMTSL1 AEBP1 TLL1 CP	2.28e-06	190	89	6	b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCell	Severe-MAIT\|Severe / Disease group and Cell class	FLT4 TTC39C EFCAB8 SARAF TMEM71 KLRG1	2.28e-06	190	89	6	1c063dc1b62d9f9912aaf8d0297555a6545f5550
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	SMARCA5 IGF2R MAN2A1 USP9X CPD DYNC1H1	2.49e-06	193	89	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	GABRE LIMK2 FLT4 TLL1 ADGRF5 DENND3	2.49e-06	193	89	6	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	facs-Diaphragm-Limb_Muscle-3m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMARCA5 IGF2R USP9X ITGB1 PTGES3 ALKBH5	2.81e-06	197	89	6	b0e2ea81308bce289cb7cbea0e27de1d01afeed2
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	FZD7 GABRG3 DSP APOBEC3C PTGFR MORN5	3.06e-06	200	89	6	9b614b8b949aa7d3ddbe613db6e08adaf04535a7
ToppCell	COVID-19-kidney-Epithelial_(EC)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRG3 FLT4 TLL1 CNTNAP2 LRP1B	7.12e-06	133	89	5	a8abb6b54862123961ae6defbf251ee6e9575258
ToppCell	COVID-19-kidney-Mito-rich_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRE FLT4 ADAMTSL1 TLL1 ADGRF5	1.08e-05	145	89	5	afed661aef990edb8e7012ab67ace56443520c9f
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FZD7 AEBP1 CP CPD ADGRA3	1.54e-05	156	89	5	bb505f639dbcad2b788db62d6084c2cb4e884bec
ToppCell	Parenchymal-10x3prime_v2-Hematologic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	APOBEC3D KIAA0825 L3MBTL3	1.67e-05	25	89	3	7b267cdcb6afcf603d566c4d5268eb44eacf47b6
ToppCell	Parenchymal-10x3prime_v2-Hematologic-Erythrocyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	APOBEC3D KIAA0825 L3MBTL3	1.67e-05	25	89	3	096ca30d9277cfd9cb2501c40b085cc358cb628b
ToppCell	Parenchymal-10x3prime_v2-Hematologic-Erythrocyte-Erythrocyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	APOBEC3D KIAA0825 L3MBTL3	1.67e-05	25	89	3	3d7b43ecf6ae64996d91765c50f614742e18bd25
ToppCell	P15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT4 ADAMTSL1 SCML2 AEBP1 CP	2.68e-05	175	89	5	84d252f3e432231687613299bbea14978bb4b06b
ToppCell	P15-Endothelial-lymphatic_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT4 ADAMTSL1 SCML2 AEBP1 CP	2.68e-05	175	89	5	a00c6fa9b33640710dd05a3799031147196f0986
ToppCell	ASK428-Epithelial-Secretory\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	GABRE FLT4 CNTNAP2 CP TMEM71	2.83e-05	177	89	5	66074a288501c136b4e83b883db5f0d8269ee326
ToppCell	COVID-19-kidney-Stressed_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRE FLT4 TLL1 ADGRF5 PTGES3	2.99e-05	179	89	5	754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRE FLT4 TLL1 ADGRF5 DENND3	3.07e-05	180	89	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	Control-Epithelial_alveolar-AT_1-AT1-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 DSP MYO3B CP DENND3	3.23e-05	182	89	5	a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCell	10x5'-Lung-Lymphocytic_B\|Lung / Manually curated celltypes from each tissue	IGLV1-47 IGLV1-44 AEBP1 GUCY2C CNTNAP2	3.23e-05	182	89	5	310f94437d197eaaaf6e30e68063b33e94befe77
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 ADAMTSL1 TLL1 KLRG1 DENND3	3.49e-05	185	89	5	bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCell	21-Trachea-Epithelial-Goblet-like_secretory\|Trachea / Age, Tissue, Lineage and Cell class	ADAMTSL1 TLL1 CP ADGRF5 PTGFR	3.59e-05	186	89	5	f8cddad28896f0edf10a8645fa49a011b22b120d
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ENOX1 CNTNAP2 PTGFR LRP1B CDH9	3.59e-05	186	89	5	8915436d09775f2828a7678af203b1082b36e21c
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	ATP13A4 PRDM11 SCML2 JMJD4 CFAP418	3.59e-05	186	89	5	5cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCell	droplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LPIN3 FLT4 ADAMTSL1 TLL1 CP	3.77e-05	188	89	5	a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ADAMTSL1 DSP MYO3B ADGRF5	3.77e-05	188	89	5	0d86044bc340e3efb90d0022dd299873639d831c
ToppCell	droplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LPIN3 FLT4 ADAMTSL1 TLL1 CP	3.77e-05	188	89	5	54550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ADAMTSL1 DSP TLL1 MYO3B	3.87e-05	189	89	5	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like\|bone_marrow / Manually curated celltypes from each tissue	FLT4 PDE8A TTC39C SARAF KLRG1	3.87e-05	189	89	5	ac2995e599f3d1813218479dc515b1d612c0ef8b
ToppCell	COVID-19-kidney-Stressed_EC\|kidney / Disease (COVID-19 only), tissue and cell type	GABRE FLT4 TLL1 ADGRF5 PTGES3	4.07e-05	191	89	5	d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCell	droplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KLHL10 FLT4 ADAMTSL1 AEBP1 CP	4.07e-05	191	89	5	51cff0594ac7ad8c065c8ea2301f8c149bd062b4
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ADAMTSL1 DSP TLL1 MYO3B	4.07e-05	191	89	5	63aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCell	10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like-MAIT\|bone_marrow / Manually curated celltypes from each tissue	FLT4 PDE8A TTC39C SARAF KLRG1	4.07e-05	191	89	5	7a28905ad504979497836e87df81d529e675ce78
ToppCell	droplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KLHL10 FLT4 ADAMTSL1 AEBP1 CP	4.07e-05	191	89	5	a55b6f0a7ec1a8852ffca593cfdccd7edea09b7b
ToppCell	droplet-Lung-30m-Endothelial-lymphatic_endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KLHL10 FLT4 ADAMTSL1 AEBP1 CP	4.07e-05	191	89	5	38681a1b182d6af5cce85db5431b6eba4b20ad96
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Late_pre-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	IGLV1-50 IGLV1-47 IGLV1-44 AEBP1 KREMEN2	4.07e-05	191	89	5	2b05be1888cccd03a32341bcb1de4a899d4179fd
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ADAMTSL1 DSP TLL1 MYO3B	4.17e-05	192	89	5	450baeb5c3df7a9445472530002ce38f177a333c
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ADAMTSL1 DSP TLL1 MYO3B	4.27e-05	193	89	5	b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ADAMTSL1 DSP TLL1 MYO3B	4.27e-05	193	89	5	b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FZD7 SMARCA5 AEBP1 CP CPD	4.27e-05	193	89	5	a313541cedfcff8fb311b9bc60157359aa103830
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW08\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	FZD7 GABRG3 APOBEC3C PTGFR MORN5	4.27e-05	193	89	5	6e9912f5444c591e698b9a7ffa3e9fc3d8ee57b0
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-MGE2\|World / Primary Cells by Cluster	GABRG3 CNTNAP2 SARAF PTGFR CDH9	4.38e-05	194	89	5	b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-MGE2-10\|World / Primary Cells by Cluster	GABRG3 CNTNAP2 SARAF PTGFR CDH9	4.38e-05	194	89	5	81e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCell	PCW_13-14-Epithelial-Epithelial_airway\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ADAMTSL1 DSP TLL1 MYO3B	4.38e-05	194	89	5	7b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ADAMTSL1 DSP TLL1 MYO3B	4.38e-05	194	89	5	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD8+_T-MAIT\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT4 TTC39C SARAF TMEM71 KLRG1	4.49e-05	195	89	5	caa3669739974b63470f7e557df96e8d3844dd84
ToppCell	COVID-19-kidney-PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	GABRE FLT4 TLL1 ADGRF5 DENND3	4.49e-05	195	89	5	a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ADAMTSL1 DSP TLL1 MYO3B	4.49e-05	195	89	5	d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT4 TTC39C SARAF TMEM71 KLRG1	4.49e-05	195	89	5	bc5728e9df0b15adec50a7c840ce9f2775135087
ToppCell	10x5'v1-week_14-16-Lymphocytic_B-B_lineage-immature_B_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	IGLV1-47 IGLV1-44 AEBP1 KREMEN2 SARAF	4.49e-05	195	89	5	ecaaa3d071e763c40d05d088fbf9e8ca06f78f47
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	GABRE FLT4 ADAMTSL1 TLL1 ADGRF5	4.60e-05	196	89	5	ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GABRE FLT4 ADAMTSL1 TLL1 ADGRF5	4.60e-05	196	89	5	95c5b8fd4ebfae1f42de9b1475c1161d4a80e515
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgA_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	FZD7 IGLV1-50 IGLV1-47 IGLV1-44 IGLV1-36	4.71e-05	197	89	5	fdbf4eb9fa5aefb4ffb307494fe4774bf5e0aaeb
ToppCell	PCW_10-12-Epithelial-Epithelial_airway\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ADAMTSL1 DSP TLL1 MYO3B	4.83e-05	198	89	5	9a12e5e47236433e512c668005fe3f8be6fde95c
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	USP9X SARAF ARIH1 ITGB1 DYNC1H1	5.06e-05	200	89	5	e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AEBP1 CP ECM1 ITGB1 PTGFR	5.06e-05	200	89	5	0655328373d1b58828e141ddb0dcbb2cce10dc50
ToppCell	COVID-19-kidney-Epithelial_Doublet\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRG3 CNTNAP2 NOX3 LRP1B	1.34e-04	130	89	4	1ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRG3 CNTNAP2 LRP1B CDH9	1.74e-04	139	89	4	a1945b07f177cde40e7eea03a19236ce76165857
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PRDM11 SCML2 EED DSP	2.21e-04	148	89	4	1186ee0d15244fee74c1d09df3967c1b69f8ddce
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRG3 ADAMTSL1 CNTNAP2 LRP1B	2.21e-04	148	89	4	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	AEBP1 CNTNAP2 CP L3MBTL3	2.27e-04	149	89	4	10ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	GABRE MYO3B PJA1 MORN5	2.33e-04	150	89	4	98fdc6bdfde84d680e11d8727502b79afbf64303
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRG3 KLHL10 CNTNAP2 LRP1B	2.33e-04	150	89	4	0205318a870e091add66ee4305747dda9f51510d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATP13A4 ENOX1 ITGA2B PTGFR	2.39e-04	151	89	4	16fc903fc71e25717b9908416f0bcd29c0a65a61
ToppCell	Int-URO-Lymphocyte-T_NK-CD4_CTL\|Int-URO / Disease, Lineage and Cell Type	IGLV1-47 ABHD16B PJA1 KLRG1	2.51e-04	153	89	4	fdc7dfa8f4db90bfdc7180bf178cf6d2dd064d97
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-Tfh\|blood / Manually curated celltypes from each tissue	FLT4 MAN2A1 SARAF USP9Y	2.57e-04	154	89	4	5ff380205fa7ab97ba21f6512bc9e14c0fb320b6
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	AEBP1 CNTNAP2 CP L3MBTL3	2.63e-04	155	89	4	99e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 ENOX1 ADGRF5 CPD	2.63e-04	155	89	4	8fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell	368C-Fibroblasts-Fibroblast-F\|368C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTSL1 ENOX1 NUP133 ADGRA3	2.77e-04	157	89	4	74038192f016f95f80e0189035ee8ccc22ceb1b8
ToppCell	368C-Fibroblasts-Fibroblast-F-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTSL1 ENOX1 NUP133 ADGRA3	2.77e-04	157	89	4	982e6ea78c7dabdb7c07c4a5fb2425d5e45b5b94
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	POLR1A CFAP418 PJA1 KLRG1	2.90e-04	159	89	4	235ed12053b337aca5abc2ce8727332b4ae3f8ae
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	GABRG3 ADAMTSL1 CNTNAP2 MYO18B	2.90e-04	159	89	4	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 EFCAB8 ADGRF5 MYO18B	2.97e-04	160	89	4	830e3ef8c9708d25872c3052a0b2682fa9372111
ToppCell	COVID-19-kidney-Epithelial_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	FLT4 TLL1 CNTNAP2 ADGRF5	2.97e-04	160	89	4	0d4880f85565d8c540c94a8f8109147b3029279a
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LIMK2 ADAMTSL1 TLL1 CP	3.04e-04	161	89	4	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC39C MYO3B TGDS LRP1B	3.12e-04	162	89	4	ca1014e32996f777bff021830ce9a7cf4acf58d5
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ADAMTSL1 TLL1 MORN5	3.34e-04	165	89	4	0c714e852f912b5749de4cb0895406673979b2e6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ADAMTSL1 TLL1 MORN5	3.34e-04	165	89	4	82530f96aaefe28a13bad0474bbad043f127a86c
ToppCell	mild_COVID-19_(asymptomatic)-pDC\|World / disease group, cell group and cell class (v2)	GPR180 SCML2 ENOX1 SLC6A20	3.50e-04	167	89	4	bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRDM11 SLC6A20 CFAP418 ADGRA3	3.50e-04	167	89	4	55c3c68af269fcf40f2b080ae4489523609ad388
ToppCell	droplet-Lung-nan-3m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ITGA2B TMEM71 MKNK1	3.66e-04	169	89	4	da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCell	droplet-Lung-nan-3m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ITGA2B TMEM71 MKNK1	3.66e-04	169	89	4	a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AEBP1 MYO3B CNTNAP2 LRP1B	3.66e-04	169	89	4	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	normal_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	IGF2R ADGRF5 ECM1 ITGB1	3.74e-04	170	89	4	d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCell	CTRL-Myeloid-Neutrophil\|Myeloid / Disease state, Lineage and Cell class	LIMK2 CPD TMEM71 DENND3	3.74e-04	170	89	4	151dabe1d240dde414c881bf4fa816c69fa1c32d
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-MAIT_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT4 TTC39C SARAF KLRG1	3.74e-04	170	89	4	059f7ae615342ea19f43b0a405cd7272251a78a9
ToppCell	facs-Liver-Non-hepatocytes-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRE SCML2 MYO3B KLRG1	3.91e-04	172	89	4	b440184f2d98d2f2d59566795f44fb79c0647ca4
ToppCell	CTRL-Myeloid-Neutrophil\|CTRL / Disease state, Lineage and Cell class	LIMK2 CPD TMEM71 DENND3	3.91e-04	172	89	4	ef3a6fe3b7300959f9f71130200c7fb8741c42b0
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT4 SCML2 TLL1 ADGRF5	4.17e-04	175	89	4	43be63976da5ad0764d24d90919a77ce46068f52
ToppCell	CF-Myeloid-Neutrophil\|Myeloid / Disease state, Lineage and Cell class	LIMK2 KIAA0825 CPD TMEM71	4.17e-04	175	89	4	8020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	FZD7 ENOX1 AEBP1 LRP1B	4.17e-04	175	89	4	fed9e4120c758fdcc23bb248d1801002b0e0d485
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 ADAMTSL1 TLL1 CP	4.17e-04	175	89	4	0801cccec6915aefc135262fc74580280fd51aa5
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 ADAMTSL1 TLL1 CP	4.17e-04	175	89	4	09163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 ADAMTSL1 TLL1 CP	4.17e-04	175	89	4	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	facs-Spleen-nan-18m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGF2R SARAF ITGB1 KLRG1	4.26e-04	176	89	4	a23d484aff5ad094333b2feae9106ca219514711
Disease	X-11315 measurement	SLC6A20 KLRG1	4.44e-04	11	85	2	EFO_0021223
Disease	R-warfarin measurement	TDRD3 ADAMTSL1 MYO3B MYO18B MKNK1	1.03e-03	265	85	5	EFO_0803324
Disease	partial epilepsy	FZD7 SMARCA5	1.08e-03	17	85	2	EFO_0004263
Disease	diet measurement, body mass index	ATP13A4 CNTNAP2	1.51e-03	20	85	2	EFO_0004340, EFO_0008111
Disease	diffuse plaque measurement	ADAMTSL1 MAN2A1 PDE8A MYO3B EFCAB8 CNTNAP2 LRP1B ADGRA3	1.54e-03	758	85	8	EFO_0010699
Disease	left atrial function	DSP MYO18B	1.66e-03	21	85	2	EFO_0004294
Disease	Parkinson Disease	IGF2R CNTNAP2 CP	1.92e-03	85	85	3	C0030567

Protein segments in the cluster

Peptide	Gene	Start	Entry
QREDEDDYEAAYWAS	NT5C1B	271	Q96P26
RYAWQDDFLEDFLCF	FAM200B	246	P0CF97
CYLVYEFDKFWFEEE	ELMOD2	246	Q8IZ81
RVKIMDYEDFAYCWE	APOBEC3D	156	Q96AK3
DYEDFAYCWENFVCN	APOBEC3D	161	Q96AK3
DDYYDGAWCAEDDAR	AEBP1	426	Q8IUX7
LFSVCLWFSEDYKEY	ATP13A4	211	Q4VNC1
WADDDYSRCQYANDV	ADGRA3	406	Q8IWK6
NYWRKSYESSEDCSE	ALKBH5	366	Q6P6C2
EIMDYEDFKYCWENF	APOBEC3C	146	Q9NRW3
EDFKYCWENFVYNDN	APOBEC3C	151	Q9NRW3
SYDDYMWDKSCDYLF	CFAP418	141	Q96NL8
DFYNCWKETEAEAQE	DENND3	691	A2RUS2
AAFYARYRVDEDWCL	ABHD16B	381	Q9H3Z7
YVYKNGTETEDCFWY	GUCY2C	191	P25092
CKEKDVDDCWFYFTY	ITGB1	691	P05556
YSDCYDFWVNADALD	L3MBTL3	301	Q96JM7
WYNCNRYNEDDAKAA	ARIH1	386	Q9Y4X5
ENFSWYLEDNIKTYC	CP	226	P00450
ATLAYRWDCSDYEDT	ANO7	446	Q6IWH7
YLWAASLAEKYCDFD	NUP133	856	Q8WUM0
DLANPEYSNFCYWRE	LPIN3	826	Q9BQK8
SIDYEENKLYWCDAR	LRP1B	2046	Q9NZR2
YDRVQADNNDYWTEC	MED13L	1261	Q71F56
WDDYKAFYEGERCSF	KIAA0825	616	Q8IV33
DFRYCEYTEWDLQFK	MAN2A1	426	Q16706
QSEDEADYYCAIWYS	IGLV5-39	106	A0A0G2JS06
SEDEADYYCKAWDNS	IGLV1-50	101	A0A075B6I6
SECQDSLTNWYYEKD	LIMK2	41	P53671
DELYDWEYEGFTKCS	ADAMTSL1	606	Q8N6G6
FEYAWCLVRSKYNDD	FIS1	36	Q9Y3D6
CFYNTEDIKDWEDRF	PTGFR	186	P43088
EDEADYYCAAWDDSL	IGLV1-47	101	P01700
YCIEWAARISEEYFS	PDE8A	736	O60658
EDEADYYCAAWDDSL	IGLV1-44	101	P01699
YVAETEEGIYWRYCD	KREMEN2	101	Q8NCW0
IFSQTWYDERLCYND	GABRE	121	P78334
WYDERLCYNDTFESL	GABRE	126	P78334
ADADENFYTCAWTYD	EED	141	O75530
YWRDNYTCPTEEEYK	GGPS1	131	O95749
SRSKAEAEAWYQCRY	KRT82	301	Q9NSB4
FKWLCYSNEAEEFIF	POMGNT2	81	Q8NAT1
TWHVFYADKYTCQDD	GPR180	121	Q86V85
LACYFYEQAFREHWE	FZD7	486	O75084
FKYCWENFVYNDDEP	APOBEC3F	336	Q8IUX4
AEAYCKTWSYREDAL	CEP104	441	O60308
TFNVECYDEKTDEWY	KLHL10	541	Q6JEL2
CYYFSVEEKDWNSSL	KLRG1	86	Q96E93
YWQEFEDTCVYECLD	GABRG3	396	Q99928
YRDNYQAFCKWLYDA	DSP	891	P15924
FWDALDVDDYRFVYA	JMJD4	211	Q9H9V9
DYNYVWANCFEITLE	CPD	336	O75976
SDCEGFVTWQKYVDY	EFCAB8	101	A8MWE9
CFEVFQTWDDEYEKL	DYNC1H1	416	Q14204
YYCNCDADYKQWRKD	CNTNAP2	741	Q9UHC6
AWEDTLDKYCDREYA	ECM1	361	Q16610
LTADCNQDYDYLSDW	CDH9	756	Q9ULB4
VDFAQARDDFYEWEC	ENOX1	216	Q8TC92
AWEDAKENYRYGLEC	LARP1B	761	Q659C4
YCYYFNEDRETWVDA	REG1A	46	P05451
FTDQATFYDKRCDLW	MKNK1	271	Q9BUB5
EVDCTYFFTWDTEYA	IGF2R	451	P11717
KRFDIDSCTYYFSWD	IGF2R	2106	P11717
DYDWERECAIKFNDY	USP9X	1801	Q93008
FIDDYQYDTEESLWC	POLR1A	1511	O95602
SEAYFENDCWVRYFL	CARS1	381	P49589
ECFALYWEDNKFYRA	TDRD3	561	Q9H7E2
YWEDNKFYRAEVEAL	TDRD3	566	Q9H7E2
GYYIWTEDSFLCDKD	TMEM71	71	Q6P5X7
EGNEVCKYDYVEIWS	TLL1	666	O43897
YDVQWECKTDLDIAY	SARAF	91	Q96BY9
EDEADYYCAAWDDSL	IGLV1-36	101	A0A0B4J1U3
DFWFCESCQEYFVDE	PRDM11	106	Q9NQV5
KYWEFAVYLEECELA	SETX	1786	Q7Z333
YVENDFSWDKRYCEA	ITGA2B	186	P08514
KVYFYWICRDARAFE	NOX3	436	Q9HBY0
DEECEKASSTQYFWY	SLC6A20	136	Q9NP91
KCISDVSNYDEVYWN	ADGRF5	491	Q8IZF2
AAAECFVQSYWEQYK	TGDS	171	O95455
AKWYDRRDYVFIEFC	PTGES3	6	Q15185
GAFDYWCKYDSRDIF	SCML2	211	Q9UQR0
AVYDWNAKQFELYDE	KIF3B	61	O15066
KLARWEYDESYCDAV	FAM20B	246	O75063
EQCEYLSYDASQWEF	FLT4	826	P35916
RFDYDWERECAIKFN	USP9Y	1801	O00507
WERECAIKFNDYFEF	USP9Y	1806	O00507
YWRECERDYQDDTLE	YLPM1	1226	P49750
WANYAAEALGCEYEE	MYO18B	851	Q8IUG5
EDTDTWLKYYDCDKY	ZNF84	171	P51523
RPAVEACYFNWEEAY	ZSWIM8	476	A7E2V4
EYSSLREEWKCEGYF	ZNF570	121	Q96NI8
FERLKNESRWSQCYY	TTC39C	376	Q8N584
EDYCMWRNYEYCRLD	SMARCA5	516	O60264
WTHSDDYYKYCDEDS	PJA1	351	Q8NG27
YDEKNWHYCDGYDRR	MORN5	76	Q5VZ52
EQQYDSSYDARCDVW	MYO3B	206	Q8WXR4