Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R19 TAS2R30 TAS2R46 TAS2R36	1.06e-04	27	185	4	GO:0033038
GeneOntologyMolecularFunction	taste receptor activity	TAS2R19 TAS2R30 TAS2R46 TAS2R36	2.37e-04	33	185	4	GO:0008527
GeneOntologyMolecularFunction	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	DNASE1L1 DICER1 FAN1	2.64e-04	14	185	3	GO:0016888
Domain	-	APC2 NCAPG ASPM HECTD1 MED12 ZYG11A NCAPD3 WDFY4 SCYL2 HEATR6 FHOD1 IPO11 SYMPK	3.63e-07	222	186	13	1.25.10.10
Domain	ARM-like	APC2 NCAPG ASPM HECTD1 MED12 ZYG11A NCAPD3 WDFY4 SCYL2 HEATR6 PELP1 FHOD1 IPO11 SYMPK	5.59e-07	270	186	14	IPR011989
Domain	ARM-type_fold	TRPC4AP APC2 ITPR1 NCAPG ASPM HECTD1 ZYG11A NCAPD3 WDFY4 SCYL2 HEATR6 PELP1 FHOD1 IPO11 SYMPK	1.61e-06	339	186	15	IPR016024
Domain	-	PRAMEF7 FBXL4 LRIG2 FBXL2 NLRC3 RABGGTA TBCE ZYG11A CARMIL1 PRAMEF20 PRAMEF8 SHOC2 NISCH	2.09e-05	321	186	13	3.80.10.10
Domain	L_dom-like	PRAMEF7 FBXL4 LRIG2 FBXL2 NLRC3 RABGGTA TBCE ZYG11A CARMIL1 PRAMEF20 PRAMEF8 SHOC2 NISCH	2.61e-05	328	186	13	IPR032675
Domain	PDEase_PDE8	PDE8A PDE8B	9.86e-05	2	186	2	IPR013938
Domain	HEAT	NCAPG NCAPD3 SCYL2 IPO11 SYMPK	2.77e-04	58	186	5	IPR000357
Domain	Pkinase_Tyr	DSTYK LMTK2 LCK GUCY2C HCK EPHA5 EPHA8	3.12e-04	129	186	7	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	DSTYK LMTK2 LCK GUCY2C HCK EPHA5 EPHA8	4.69e-04	138	186	7	IPR001245
Domain	VWF_type-D	VWF SUSD2 OTOG	4.95e-04	16	186	3	IPR001846
Domain	VWFD	VWF SUSD2 OTOG	4.95e-04	16	186	3	PS51233
Domain	VWD	VWF SUSD2 OTOG	4.95e-04	16	186	3	SM00216
Domain	VWD	VWF SUSD2 OTOG	4.95e-04	16	186	3	PF00094
Domain	SHR-BD	VPS13D VPS13B	5.84e-04	4	186	2	IPR009543
Domain	VPS13_C	VPS13D VPS13B	5.84e-04	4	186	2	PF16909
Domain	VPS13_C	VPS13D VPS13B	5.84e-04	4	186	2	IPR031645
Domain	SHR-BD	VPS13D VPS13B	5.84e-04	4	186	2	PF06650
Domain	HEAT_REPEAT	NCAPG NCAPD3 SCYL2 HEATR6 IPO11	6.65e-04	70	186	5	PS50077
Domain	PDEase	PDE8A PDE9A PDE8B	8.37e-04	19	186	3	IPR023088
Domain	PRAME_family	PRAMEF7 PRAMEF20 PRAMEF8	8.37e-04	19	186	3	IPR026271
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	PRAMEF7 ABCA1 WDR81 BIRC6 ITPR1 RGL1 SYDE2 ASPM DDX39B PRAMEF20 HECTD4 PRAMEF8 PDE4DIP	1.43e-07	363	193	13	14691545
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	MYO7A STRC STRCP1 OTOG	2.94e-07	11	193	4	31776257
Pubmed	Defining the membrane proteome of NK cells.	ABR KATNB1 PSMC3 PTBP1 ADAM10 BIRC6 ITPR1 NCAPG GANAB BST2 ATP11A MED12 NPC1 NCAPD3 RNF213 CIT PELP1 NISCH FHOD1 IRAG2 ITPRIP IFT122	6.48e-07	1168	193	22	19946888
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BIRC6 LRIG2 RGL1 DSTYK ATP11A HECTD1 PREX1 MED12 BAZ2B RNF213 WDFY4 FAN1 VPS13D LMBR1L	7.70e-07	493	193	14	15368895
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PDE9A APC2 ZEB2 HECTD1 PREX1 DOP1B NPC1 VWF HECTD4 SEC31B CIT FAN1 SCYL2 SPTBN4 FRY HEATR6 CELSR3 ZNF592 NISCH PDE4DIP MRPS9 IFT122 ZNF292	8.51e-07	1285	193	23	35914814
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	RGL1 DOP1B FRMPD1 CIT DICER1 FAN1 NISCH	1.72e-06	102	193	7	10231032
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	PRAMEF7 TRPC4AP MYO7A SKIDA1 NHLRC2 OTUB2 ASPM ATP11A MAD2L2 MCF2L DOP1B FNIP2 DSC2 CARMIL1 PRAMEF20 PRAMEF8 CIT IRAG2 CD300LG RAB15 SYMPK	6.32e-06	1242	193	21	30973865
Pubmed	Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.	MYO7A STRC STRCP1	9.23e-06	8	193	3	21165971
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABR MYO7A ADGRB2 EXOSC8 BIRC6 MCF2L HECTD1 PREX1 UVRAG MED12 NPC1 HECTD4 LMTK2 CIT GRAMD2A CELSR3 ZNF592 NISCH SYMPK	1.42e-05	1105	193	19	35748872
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	ADAM10 ITPR1 DSTYK VWF DSC2 CARMIL1 RNF213 CLCA2 GUCY2C PDE8B PDE4DIP IRAG2 ITPRIP	1.44e-05	552	193	13	10737800
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	ZSWIM3 NHLRC2 BIRC6 FBXL4 FANCD2 GANAB KIF2B ASPM OXSM HECTD1 MED12 TBCE NELFA DICER1 SLC22A9 SMG8 PELP1 MRPS9 RAB15 ZNF292 RGL4	1.70e-05	1327	193	21	32694731
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	BMS1 PTBP1 MYO5C HECTD1 NCAPD3 CIT DICER1 HEATR6	1.86e-05	202	193	8	33005030
Pubmed	Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases.	ADAM10 LCK HCK	1.96e-05	10	193	3	11741929
Pubmed	Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.	MYO7A STRC STRCP1	2.69e-05	11	193	3	31448880
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MEX3C POLR1F PTPN14 SYDE2 DSTYK HECTD1 UVRAG DOP1B DSC2 CARMIL1 LMTK2 LCK VPS13D DYRK1B SAMD4A OTOG	2.77e-05	861	193	16	36931259
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	PDE8A WDR81 ITPR1 LRIG2 UVRAG DOP1B NPC1 FNIP2 VPS13D NISCH WDR41 VPS13B	2.78e-05	504	193	12	34432599
Pubmed	cAMP-specific phosphodiesterases 8A and 8B, essential regulators of Leydig cell steroidogenesis.	PDE8A PDE8B	3.06e-05	2	193	2	22232524
Pubmed	ASPM and citron kinase co-localize to the midbody ring during cytokinesis.	ASPM CIT	3.06e-05	2	193	2	17534152
Pubmed	Murine calmodulin binding protein 1 (Calmbp1): tissue-specific expression during development and in adult tissues.	ASPM APAF1	3.06e-05	2	193	2	12351193
Pubmed	MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis.	PIWIL1 DICER1	3.06e-05	2	193	2	16938833
Pubmed	The E3 ubiquitin ligase, HECTD1, is involved in ABCA1-mediated cholesterol export from macrophages.	ABCA1 HECTD1	3.06e-05	2	193	2	29306077
Pubmed	The high-affinity cAMP-specific phosphodiesterase 8B controls steroidogenesis in the mouse adrenal gland.	PDE8A PDE8B	3.06e-05	2	193	2	21187369
Pubmed	The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.	LCK HCK	3.06e-05	2	193	2	9705913
Pubmed	HIV-1 Nef disrupts membrane-microdomain-associated anterograde transport for plasma membrane delivery of selected Src family kinases.	LCK HCK	3.06e-05	2	193	2	23601552
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	3.06e-05	2	193	2	34910522
Pubmed	Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation.	LCK HCK	3.06e-05	2	193	2	10364375
Pubmed	Streamlined platform for short hairpin RNA interference and transgenesis in cultured mammalian cells.	PTBP1 PTBP2	3.06e-05	2	193	2	21768390
Pubmed	C11ORF74 interacts with the IFT-A complex and participates in ciliary BBSome localization.	IFTAP IFT122	3.06e-05	2	193	2	30476139
Pubmed	Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability.	FANCD2 FAN1	3.06e-05	2	193	2	26797144
Pubmed	Comparison of enzymatic characterization and gene organization of cyclic nucleotide phosphodiesterase 8 family in humans.	PDE8A PDE8B	3.06e-05	2	193	2	12681444
Pubmed	Diva vaccines that reduce virus transmission.	BCL2L10 APAF1	3.06e-05	2	193	2	10486928
Pubmed	cAMP-specific phosphodiesterase 8A and 8B isoforms are differentially expressed in human testis and Leydig cell tumor.	PDE8A PDE8B	3.06e-05	2	193	2	36277728
Pubmed	Alternative splicing of brain-specific PTB defines a tissue-specific isoform pattern that predicts distinct functional roles.	PTBP1 PTBP2	3.06e-05	2	193	2	12213192
Pubmed	EphA8 acts as an oncogene and contributes to poor prognosis in gastric cancer via regulation of ADAM10.	ADAM10 EPHA8	3.06e-05	2	193	2	31026069
Pubmed	PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons.	PTBP1 PTBP2	3.06e-05	2	193	2	27681424
Pubmed	ADP-ribosyl cyclase and ryanodine receptor activity contribute to basal renal vasomotor tone and agonist-induced renal vasoconstriction in vivo.	RYR2 CD38	3.06e-05	2	193	2	17652368
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	3.06e-05	2	193	2	11687802
Pubmed	Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents.	FANCD2 FAN1	3.06e-05	2	193	2	20603016
Pubmed	Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells.	GLS2 DICER1	3.06e-05	2	193	2	27725225
Pubmed	DANGER, a novel regulatory protein of inositol 1,4,5-trisphosphate-receptor activity.	ITPR1 ITPRIP	3.06e-05	2	193	2	16990268
Pubmed	Spatiotemporal expression of otogelin in the developing and adult mouse inner ear.	MYO7A OTOG	3.06e-05	2	193	2	11506947
Pubmed	TFG-maintaining stability of overlooked FANCD2 confers early DNA-damage response.	TFG FANCD2	3.06e-05	2	193	2	33099537
Pubmed	Epistasis between intracellular cholesterol trafficking-related genes (NPC1 and ABCA1) and Alzheimer's disease risk.	ABCA1 NPC1	3.06e-05	2	193	2	20571217
Pubmed	Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death.	BCL2L10 APAF1	3.06e-05	2	193	2	9829980
Pubmed	A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons.	PTBP1 PTBP2	3.06e-05	2	193	2	17606642
Pubmed	ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity.	ABCA1 NPC1	3.06e-05	2	193	2	12215451
Pubmed	Direct interaction of the CD38 cytoplasmic tail and the Lck SH2 domain. Cd38 transduces T cell activation signals through associated Lck.	LCK CD38	3.06e-05	2	193	2	10636863
Pubmed	The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.	TAS2R19 TAS2R30 TAS2R46	3.57e-05	12	193	3	12379855
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	PRAMEF7 ITPR1 AREL1 EXOC3L4 FAM20B ATP11A NPC1 ZWILCH PTBP2 PRAMEF20 FRMPD1 LMTK2 PRAMEF8 WDFY4 GRAMD2A UNC5C ITPRIP VPS13B	3.79e-05	1084	193	18	11544199
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	MYO7A PTBP1 BIRC6 RYR2 MEX3C IQCN SCYL2	4.52e-05	168	193	7	30631154
Pubmed	Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.	TAS2R19 TAS2R30 TAS2R46	4.62e-05	13	193	3	15938754
Pubmed	Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation.	NCAPG HECTD1 NCAPD3	5.85e-05	14	193	3	26166704
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MYO7A BMS1 SRP68 BIRC6 OTUB2 SYDE2 EXOC3L4 DOP1B BAZ2B RNF213 FRY ZNF592 SYMPK RGL4	6.94e-05	736	193	14	29676528
Pubmed	Identification of SH3 domain proteins interacting with the cytoplasmic tail of the a disintegrin and metalloprotease 10 (ADAM10).	ADAM10 LCK HCK	7.29e-05	15	193	3	25036101
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	PSMC3 SRP68 ADAM10 FANCD2 NCAPG GANAB FAM20B SLC30A9 HECTD1 NPC1 NCAPD3 DSC2 LMBR1L NISCH IPO11 SYMPK	7.98e-05	942	193	16	31073040
Pubmed	Partial transcriptome of the developing pituitary gland.	POLR1F ZHX1-C8orf76 C8orf76	8.93e-05	16	193	3	11161784
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	9.16e-05	3	193	2	30801007
Pubmed	The chromatoid body of male germ cells: similarity with processing bodies and presence of Dicer and microRNA pathway components.	PIWIL1 DICER1	9.16e-05	3	193	2	16477042
Pubmed	FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.	FANCD2 FAN1	9.16e-05	3	193	2	20671156
Pubmed	Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search.	PDE8B WDR41	9.16e-05	3	193	2	21502949
Pubmed	The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr.	PTBP1 PTBP2	9.16e-05	3	193	2	12667457
Pubmed	The Src-like tyrosine kinase Hck is activated by granulocyte colony-stimulating factor (G-CSF) and docks to the activated G-CSF receptor.	LCK HCK	9.16e-05	3	193	2	9790917
Pubmed	A Genetic Screen Identifies a Critical Role for the WDR81-WDR91 Complex in the Trafficking and Degradation of Tetherin.	WDR81 BST2	9.16e-05	3	193	2	27126989
Pubmed	ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.	ABCA1 NPC1	9.16e-05	3	193	2	22179027
Pubmed	Expression of splice variants of the human ADAM15 gene and strong interaction between the cytoplasmic domain of one variant and Src family proteins Lck and Hck.	LCK HCK	9.16e-05	3	193	2	15263807
Pubmed	Potentially functional genetic variants in microRNA processing genes and risk of HBV-related hepatocellular carcinoma.	PIWIL1 DICER1	9.16e-05	3	193	2	23868705
Pubmed	Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy.	EPHA5 EPHA8	9.16e-05	3	193	2	27582484
Pubmed	Spire1 and Myosin Vc promote Ca2+-evoked externalization of von Willebrand factor in endothelial cells.	MYO5C VWF	9.16e-05	3	193	2	35084586
Pubmed	Differential regulation of ATP binding cassette protein A1 expression and ApoA-I lipidation by Niemann-Pick type C1 in murine hepatocytes and macrophages.	ABCA1 NPC1	9.16e-05	3	193	2	17553802
Pubmed	MRG15 is required for pre-mRNA splicing and spermatogenesis.	PTBP1 PTBP2	9.16e-05	3	193	2	27573846
Pubmed	ADAM10 inhibits the interaction between IL-17 and HMGB1 in Buerger's disease.	IL17A ADAM10	9.16e-05	3	193	2	34156683
Pubmed	IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact.	ITPR1 BCL2L10	9.16e-05	3	193	2	27995898
Pubmed	MIWI prevents aneuploidy during meiosis by cleaving excess satellite RNA.	PIWIL1 DICER1	9.16e-05	3	193	2	32677148
Pubmed	Dysregulated ryanodine receptors mediate cellular toxicity: restoration of normal phenotype by FKBP12.6.	RYR2 ITPR1	9.16e-05	3	193	2	12754204
Pubmed	EphrinA/EphA-induced ectodomain shedding of neural cell adhesion molecule regulates growth cone repulsion through ADAM10 metalloprotease.	ADAM10 EPHA5	9.16e-05	3	193	2	24117969
Pubmed	Expression of human nPTB is limited by extreme suboptimal codon content.	PTBP1 PTBP2	9.16e-05	3	193	2	18335065
Pubmed	Human KIAA1018/FAN1 nuclease is a new mitotic substrate of APC/C(Cdh1).	FANCD2 FAN1	9.16e-05	3	193	2	22854063
Pubmed	Analysis of regulatory polymorphisms in organic ion transporter genes (SLC22A) in the kidney.	SLC22A9 SLC22A2	9.16e-05	3	193	2	18414781
Pubmed	Elevated IL-17A and IL-22 regulate expression of inducible CD38 and Zap-70 in chronic lymphocytic leukemia.	IL17A CD38	9.16e-05	3	193	2	27718514
Pubmed	Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2.	PTBP1 PTBP2	9.16e-05	3	193	2	27791185
Pubmed	Polypyrimidine tract binding protein 2 stabilizes phosphoglycerate kinase 2 mRNA in murine male germ cells by binding to its 3'UTR.	PTBP1 PTBP2	9.16e-05	3	193	2	17329592
Pubmed	Intracellular calcium release channel expression during embryogenesis.	RYR2 ITPR1	9.16e-05	3	193	2	9986730
Pubmed	Nodal β spectrins are required to maintain Na+ channel clustering and axon integrity.	SPTBN4 AVIL	9.16e-05	3	193	2	32052742
Pubmed	PTBP1 and PTBP2 impaired autoregulation of SRSF3 in cancer cells.	PTBP1 PTBP2	9.16e-05	3	193	2	26416554
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	ERCC6 BMS1 SRP68 EXOSC8 PTBP1 BIRC6 POLR1F ASPM HECTD1 MED12 NCAPD3 SRBD1 PELP1 KCTD20	9.59e-05	759	193	14	35915203
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	PSMC3 SRP68 PTBP1 NCAPG DDX39B NCAPD3 RNF213 PELP1 SYMPK	1.08e-04	332	193	9	32786267
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF7 PRAMEF20 PRAMEF8	1.08e-04	17	193	3	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF7 PRAMEF20 PRAMEF8	1.08e-04	17	193	3	37781892
Pubmed	Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.	STRC STRCP1 OTOG	1.08e-04	17	193	3	20856818
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	PSMC3 SRP68 PTBP1 FANCD2 NCAPG DDX39B PTBP2 SHOC2 SEC31B SCYL2 FHOD1 SYMPK	1.09e-04	582	193	12	20467437
Pubmed	A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.	MYO7A MCF2L NLRC3 PTBP2 CIT	1.14e-04	85	193	5	23055939
Pubmed	Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.	PDE8A PSMC3 TFG ADCY8 RYR2 MED12 IPO11	1.15e-04	195	193	7	17110338
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	BMS1 SRP68 PTBP1 TFG BIRC6 RYR2 LRIG2 SYDE2 DSC2 RNF213 UNC5C MRPS9 WDR41 RPGR	1.22e-04	777	193	14	35844135
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF7 PRAMEF20 PRAMEF8	1.29e-04	18	193	3	23894331
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF7 PRAMEF20 PRAMEF8	1.29e-04	18	193	3	39181896
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF7 PRAMEF20 PRAMEF8	1.29e-04	18	193	3	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF7 PRAMEF20 PRAMEF8	1.29e-04	18	193	3	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF7 PRAMEF20 PRAMEF8	1.29e-04	18	193	3	14675769
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF7 PRAMEF20 PRAMEF8	1.53e-04	19	193	3	28604677
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	TRPC4AP BMS1 PSMC3 PTBP1 DDX39B SCYL2 GRAMD2A VPS13D	1.70e-04	277	193	8	30745168
Interaction	NPTN interactions	FANCD2 GANAB DSTYK MAD2L2 DOP1B ZWILCH RNF213 SMG8 HEATR6 LMBR1L FHOD1 IPO11 SYMPK	1.13e-06	278	177	13	int:NPTN
Interaction	SMC4 interactions	PSMC3 FANCD2 NCAPG GANAB ASPM HECTD1 MED12 NCAPD3 ZWILCH CIT LMBR1L MOB3C	7.48e-06	281	177	12	int:SMC4
Interaction	RRAS interactions	FANCD2 ASPM METTL22 NPC1 RIN1 FHOD1	1.42e-05	60	177	6	int:RRAS
GeneFamily	Taste 2 receptors	TAS2R19 TAS2R30 TAS2R46 TAS2R36	1.53e-04	39	126	4	1162
GeneFamily	PRAME family	PRAMEF7 PRAMEF20 PRAMEF8	6.01e-04	24	126	3	686
GeneFamily	Phosphodiesterases	PDE8A PDE9A PDE8B	6.01e-04	24	126	3	681
GeneFamily	WD repeat domain containing\|BEACH domain containing	WDR81 WDFY4	1.68e-03	9	126	2	1230
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ABR SYDE2 UVRAG	1.99e-03	36	126	3	823
GeneFamily	WD repeat domain containing	KATNB1 WDR81 APAF1 SEC31B WDFY4 IFT122 WDR41	2.42e-03	262	126	7	362
Coexpression	GSE20152_SPHK1_KO_VS_HTNFA_OVEREXPRESS_ANKLE_UP	TFG GPR171 DDX39B FRMPD1 DICER1 NISCH FHOD1 RAB15 PAQR3	1.33e-05	197	188	9	M7682
Coexpression	GSE39556_CD8A_DC_VS_NK_CELL_DN	MTSS1 ZEB2 UVRAG DOP1B GUCY2C CD38 IRAG2 HCK VPS13B	1.39e-05	198	188	9	M9407
Coexpression	GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN	TRPC4AP NHLRC2 ZEB2 ITPR1 LRIG2 ATP11A SLC30A9 LCK ITPRIP	1.45e-05	199	188	9	M3517
Coexpression	FARMER_BREAST_CANCER_CLUSTER_1	IFI44L GPR171 HERC6 LCK CD38	2.40e-05	48	188	5	M15015
Coexpression	GSE4984_GALECTIN1_VS_LPS_STIM_DC_DN	SYCP2L SRP68 PTBP1 FANCD2 ATP11A SDHB NELFA IRAG2	3.15e-05	169	188	8	M6504
Coexpression	ZAK_PBMC_MRKAD5_HIV_1_GAG_POL_NEF_AGE_20_50YO_1DY_UP	HCAR2 ABCA1 CEACAM3 ZEB2 RGL1 BST2 ATP11A IFI44L HERC6 DNASE1L1 RABGGTA SDHB FNIP2 RNF213 DICER1 RIN1 CD38 WDR41 HCK SAMD4A	4.29e-05	1012	188	20	M40868
Coexpression	XIE_ST_HSC_S1PR3_OE_UP	ABCA1 PDE9A RYR2 BST2 IFI44L HERC6 RNF213 LCK	6.95e-05	189	188	8	M41755
Coexpression	GAUCHER_PBMC_YF_VAX_STAMARIL_UNKNOWN_AGE_10DY_UP	ABCA1 RGL1 BST2 IFI44L HERC6 SRBD1 CD38 SAMD4A	8.96e-05	196	188	8	M41141
Coexpression	GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_DN	KATNB1 MTSS1 LRIG2 RGL1 ATP11A MAD2L2 CABP7 GUCY2C	9.61e-05	198	188	8	M6731
Coexpression	GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_UP	ABR GLS2 MTSS1 CD83 UVRAG LCK IRAG2 HCK	9.95e-05	199	188	8	M9414
Coexpression	GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_DN	RGL1 BST2 IFI44L HERC6 TBCE FNIP2 SRBD1 SAMD4A	9.95e-05	199	188	8	M3286
Coexpression	GSE22886_CTRL_VS_LPS_24H_DC_DN	MTSS1 CD83 BST2 IFI44L HERC6 HEATR6 LMBR1L PAQR3	1.03e-04	200	188	8	M4520
Coexpression	GSE27786_BCELL_VS_MONO_MAC_DN	CCN5 DSTYK ASPM MCF2L VWF CRAT VPS13D CLCA2	1.03e-04	200	188	8	M4818
Coexpression	GSE33424_CD161_INT_VS_NEG_CD8_TCELL_UP	ZEB2 IFI44L GPR171 HERC6 CARMIL1 RNF213 CHRAC1 HCK	1.03e-04	200	188	8	M8554
Coexpression	GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_UP	BST2 IFI44L HERC6 DOP1B CARMIL1 CA13 RNF213 HCK	1.03e-04	200	188	8	M8564
Coexpression	GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN	OR7C1 ADAM10 PTPN14 BST2 SYDE2 IRAG2 CDYL2 SAMD4A	1.03e-04	200	188	8	M3659
Coexpression	GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_DN	ABR UVRAG RABGGTA DOP1B NCAPD3 CD38 IRAG2 VPS13B	1.03e-04	200	188	8	M7658
Coexpression	ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN	ITPR1 CCN5 DSC2 ZNF654 SAMD4A ZNF292	1.07e-04	104	188	6	M6189
Coexpression	LU_AGING_BRAIN_UP	MTSS1 ZEB2 POLR1F DNASE1L1 NPC1 VWF BAZ2B RIN1 PDE4DIP	1.26e-04	263	188	9	M5547
CoexpressionAtlas	DevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#4_top-relative-expression-ranked_500	ABCA1 PDE8A MYO7A PREX1 VWF WDFY4 CLCA2 CD38 IRAG2 IPO11	1.27e-05	217	174	10	gudmap_developingKidney_e15.5_Endothelial cells_500_k4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	MTSS1 CD83 TFG ZEB2 ITPR1 UVRAG WDFY4 IRAG2 RPGR	3.95e-08	163	192	9	6bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	MTSS1 CD83 ZEB2 ITPR1 IFI44L UVRAG WDFY4 IRAG2 RPGR	6.59e-08	173	192	9	d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	ADAM10 BIRC6 ZEB2 LRIG2 UTY DOP1B NPC1 RNF213 ZNF292	1.17e-07	185	192	9	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	ADAM10 BIRC6 ZEB2 LRIG2 UTY DOP1B NPC1 RNF213 ZNF292	1.23e-07	186	192	9	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	MTSS1 ZEB2 RGL1 NCAPG ASPM PREX1 RNF213 WDFY4 HCK	1.61e-07	192	192	9	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	facs-Skin-Telogen-3m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRB2 GPR55 GPR171 PREX1 LCK GUCY2C AVIL IRAG2	1.00e-06	176	192	8	3d372c1d527fcc118d1e5809f2524fc387682472
ToppCell	facs-Skin-Telogen-3m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRB2 GPR55 GPR171 PREX1 LCK GUCY2C AVIL IRAG2	1.00e-06	176	192	8	9c0fb2c6ae84febdf7c3d4e648985f597dcffe7a
ToppCell	facs-Skin-Telogen-3m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRB2 GPR55 GPR171 PREX1 LCK GUCY2C AVIL IRAG2	1.00e-06	176	192	8	7b3f3d9b33770edf294cee0eccaf8a46f9331461
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	ABCA1 ABR CD83 ZEB2 FNIP2 WDFY4 PDE4DIP HCK	1.92e-06	192	192	8	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA1 ABR MTSS1 ZEB2 RGL1 PREX1 WDFY4 HCK	2.08e-06	194	192	8	1dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MTSS1 CD83 ZEB2 ITPR1 UVRAG SHOC2 WDFY4 RPGR	2.16e-06	195	192	8	481989d2e5bd2582da3d86b0155c4d6615317067
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA1 ABR CD83 ZEB2 RGL1 PREX1 WDFY4 HCK	2.16e-06	195	192	8	247803cf58c6d9c561a52aa34e581188ddad197e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MTSS1 CD83 ZEB2 ITPR1 UVRAG SHOC2 WDFY4 RPGR	2.16e-06	195	192	8	6108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA1 ABR MTSS1 ZEB2 PREX1 WDFY4 CD38 HCK	2.16e-06	195	192	8	34a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA1 ABR CD83 ZEB2 RGL1 PREX1 WDFY4 HCK	2.33e-06	197	192	8	8af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE9A CEACAM3 DSC2 GUCY2C AVIL UNC5C IRAG2 HCK	2.42e-06	198	192	8	a631be84e29c277216d89ec6265bd43e87c1dc86
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 MYO7A MTSS1 ZEB2 RGL1 PREX1 WDFY4 HCK	2.51e-06	199	192	8	9545ac59c8d75f5747dff86cb511a149dc103b31
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 ABR MYO7A CD83 ZEB2 RGL1 WDFY4 HCK	2.60e-06	200	192	8	78d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTSS1 GPR55 MYO5C ATP2C2 MCF2L DOP1B CLCA2	3.72e-06	148	192	7	f58804d24fe524b42b5090c8658050ea4b14793e
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-T-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR171 NLRC3 CABP7 BCL2L10 LCK PAFAH2 OTOG	4.24e-06	151	192	7	b85a763459a0f019d1f9975d09b9f2247d62c9d3
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIWIL1 FANCD2 NCAPG ASPM NCAPD3 ZWILCH CIT	7.02e-06	163	192	7	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA1 CD83 RGL1 DNASE1L1 WDFY4 FHOD1 HCK	9.23e-06	170	192	7	9ac1ef57f14418a5dd2aa16861c3df698c28f5ed
ToppCell	Mild/Remission-B_naive-8\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MTSS1 ZEB2 IFI44L DOP1B BAZ2B RPGR HCK	1.03e-05	173	192	7	694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-B_cells-Memory_B\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD83 ZEB2 PREX1 ZYG11A WDFY4 CD38 IRAG2	1.20e-05	177	192	7	0d1c39e99144fdb9c7f6f98a1ade41c73db45b65
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEX3C ITPR1 DSTYK FNIP2 SRBD1 CD38 KCTD20	1.29e-05	179	192	7	dd94ebe69ade6f51b94058abe066216f0de9feda
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	HCAR2 OR7C1 CD83 ZEB2 SEC31B HCK	1.43e-05	121	192	6	b6dada0712b1f9793bc61e54ec7f10c9eaf53b86
ToppCell	droplet-Heart-nan-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN14 BST2 MCF2L VWF FRY CD38 CD300LG	1.60e-05	185	192	7	a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MTSS1 CARMIL1 OR14A16 FRY AVIL IRAG2 HCK	1.96e-05	191	192	7	54f07e4de61735051498846afb44b1798bed8144
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	ABR CD83 ZEB2 PREX1 FNIP2 WDFY4 HCK	1.96e-05	191	192	7	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	ADAM10 BIRC6 ZEB2 UTY DOP1B RNF213 ZNF292	1.96e-05	191	192	7	9454f642c3621370fa23640b631301346b300950
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	ABCA1 ABR ZEB2 RGL1 PREX1 WDFY4 HCK	2.10e-05	193	192	7	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	LRIG2 IFI44L TAS2R30 RNF213 SEC31B VPS13B ZNF292	2.10e-05	193	192	7	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	moderate-Myeloid-Monocyte-derived_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RGL1 BST2 IFI44L HERC6 RNF213 CD38 SAMD4A	2.10e-05	193	192	7	22455801194bd8c73c5c397f5eac4f723429c383
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYO7A MTSS1 ZEB2 RGL1 PREX1 IRAG2 HCK	2.17e-05	194	192	7	663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCell	COVID-19_Severe-Classical_Monocyte-cMono_4\|Classical_Monocyte / Disease condition and Cell class	HCAR2 ABCA1 CD83 BST2 IFI44L RNF213 SAMD4A	2.24e-05	195	192	7	1992a1673b7213e25f3c76ac77da35c57daceddd
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	ABCA1 ABR MTSS1 ZEB2 RGL1 WDFY4 HCK	2.24e-05	195	192	7	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	CF-Myeloid\|CF / Disease state, Lineage and Cell class	HCAR2 CEACAM3 CD83 ZEB2 PREX1 FRY HCK	2.24e-05	195	192	7	ecf604de496f389a49429d0bb211e1db6019cc8b
ToppCell	Adult-Immune-monocyte-D231\|Adult / Lineage, Cell type, age group and donor	MTSS1 CEACAM3 ZEB2 PREX1 APAF1 IRAG2 HCK	2.24e-05	195	192	7	ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	ABR CD83 ZEB2 FNIP2 WDFY4 CD38 HCK	2.24e-05	195	192	7	ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCell	facs-Aorta-Heart-3m-Endothelial-aorta_endothelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A MTSS1 RGL1 EXOC3L4 MCF2L CD38 ITPRIP	2.24e-05	195	192	7	3969b8d5fcec8ef1831531a781f7bbcebab5a4ba
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CEACAM3 CD83 GPR171 PREX1 WDFY4 CD38 HCK	2.32e-05	196	192	7	b71d711be5609115b00a57700885aca608920896
ToppCell	COVID-19-Myeloid-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	ABCA1 ABR CD83 ZEB2 RGL1 PREX1 FNIP2	2.32e-05	196	192	7	4929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell	COVID-19-lung-Macrophage_metabolically_active\|lung / Disease (COVID-19 only), tissue and cell type	ABCA1 ABR MYO7A ZEB2 RGL1 WDFY4 HCK	2.32e-05	196	192	7	a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCell	moderate-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ABCA1 IL17A IFI44L GPR171 DDX39B RNF213 LCK	2.32e-05	196	192	7	9152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCell	Mild/Remission\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MTSS1 CD83 IFI44L HERC6 UVRAG RPGR ZNF292	2.32e-05	196	192	7	71603a3b7df40eb3f267345f55e44a812fea7926
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	HCAR2 CD83 ZEB2 PREX1 FNIP2 HCK IPO11	2.32e-05	196	192	7	ff88e5b919b1be93159ad2200a7786d1c5272724
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABR CD83 ZEB2 PREX1 RNF213 WDFY4 HCK	2.39e-05	197	192	7	e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCell	COVID-19\|World / Condition, Lineage and Cell class	MTSS1 RGL1 IFI44L GPR171 RNF213 LCK CD38	2.39e-05	197	192	7	228f641d79282cc3dc51b95a1f4b0cccfc200735
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 MYO7A MTSS1 ZEB2 RGL1 WDFY4 HCK	2.47e-05	198	192	7	c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCell	COVID-19-kidney-Macrophages\|kidney / Disease (COVID-19 only), tissue and cell type	ABCA1 ABR ZEB2 PREX1 WDFY4 CD38 HCK	2.47e-05	198	192	7	161324541fe5da5cbb58142ea94fefd39b7dfb04
ToppCell	moderate-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MTSS1 CD83 ZEB2 RGL1 NPC1 FNIP2 PDE4DIP	2.55e-05	199	192	7	3895e367a33ac0316f96a64c07574de99684f4b7
ToppCell	wk_15-18-Hematologic-Myeloid-SPP1+_Mac\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ABCA1 MYO7A MTSS1 CD83 RGL1 BST2 HCK	2.55e-05	199	192	7	c7fc2ac1601346aac71e7620a8a440fde8d92dbd
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	ABR HECTD1 FNIP2 BAZ2B FRY ZNF292 EPHA5	2.64e-05	200	192	7	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 MYO7A CD83 ZEB2 RGL1 DSC2 HCK	2.64e-05	200	192	7	77a68e8fd97a3f3467d25032067fd7ad52ab8522
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NLRC3 BCL2L10 LCK CD38 PAFAH2 OTOG	4.13e-05	146	192	6	a5c84ad44d6ffb25028a4fd5454fd5de81b16a5e
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Mast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NLRC3 BCL2L10 LCK CD38 PAFAH2 OTOG	4.13e-05	146	192	6	8133037881c15e75637fc616091a7055488dd5fc
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-4\|TCGA-Brain / Sample_Type by Project: Shred V9	GLS2 SPATA31C1 RYR2 ITPR1 STRCP1 SLC22A9	4.62e-05	149	192	6	ff472ad641efd655905e99a9a4cacd5245ab8854
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|368C / Donor, Lineage, Cell class and subclass (all cells)	GPR55 ATP2C2 NLRC3 LCK CELSR3 DYRK1B	4.80e-05	150	192	6	c843bcf98c5fad2ca4339602f721f3fb782ae353
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp-Endothelial_Tip.Dcn.Mgp-Penk_(Penk)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CCN5 PROZ CA13 SEC31B GUCY2C	5.42e-05	94	192	5	8fb9adf0db3b0007204716869d895700cbdc6231
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Coch_(Coch)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GPR55 EXOC3L4 DSC2 SLC22A2 EPHA8	6.30e-05	97	192	5	adda7a49b7754ed110e212346768bf52107c26fc
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Coch_(Coch)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GPR55 EXOC3L4 DSC2 SLC22A2 EPHA8	6.30e-05	97	192	5	6d865ec3a413f595de17e0a5f8c61666ebb3e252
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GPR55 EXOC3L4 DSC2 SLC22A2 EPHA8	6.30e-05	97	192	5	2cd5cafdf0a9a468baaafd4613d790fc048ee53e
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR55 MYO5C ATP2C2 MCF2L DOP1B CLCA2	6.63e-05	159	192	6	c9e093d7c1dca83f6546adaf3d874929e2cea612
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SKIDA1 NCAPG ASPM NELFA FRMPD1 SLC22A9	6.63e-05	159	192	6	2233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADGRB2 GPR171 PREX1 NLRC3 LCK IRAG2	6.87e-05	160	192	6	e4516b093003275084fc327d1597394a436754eb
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADGRB2 GPR171 PREX1 NLRC3 LCK IRAG2	6.87e-05	160	192	6	0a507e3d59d7f744d0201a531ea84fa97a68aedb
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MTSS1 GPR55 MYO5C CARMIL1 AVIL IRAG2	7.35e-05	162	192	6	80619a93c57fe16daf91dc571874ef9ac888953d
ToppCell	Control-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MTSS1 ZEB2 KIF2B SPTBN4 IRAG2 HCK	7.35e-05	162	192	6	aa80452b972bb8ad3670ffaba4ce26fadb33b185
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	GPR55 ATP2C2 FNIP2 CELSR3 ZNF592 DYRK1B	7.35e-05	162	192	6	ca30d9bf61f4133566fdc91c7996e130ea554d01
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IDI2-AS1 BST2 IFI44L GPR171 HERC6 MOB3C	7.61e-05	163	192	6	d005115aa1e1458b51de7eb719794617a4168608
ToppCell	COVID-19_Severe-multiplets\|World / disease group, cell group and cell class	NCAPG ASPM IFI44L CIT GRAMD2A CD38	7.61e-05	163	192	6	6db4271c2d47a9c333964f36d2c32207115e52cd
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO5C CIT CELSR3 PAFAH2 MOB3C RAB15	7.87e-05	164	192	6	4ef776d1bab4103d42d3a4f22cdfb49e8d2bc5a0
ToppCell	Healthy_Control-Lymphoid-T-innate_T\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	IL17A ADGRB2 GPR171 NLRC3 LCK RGL4	8.14e-05	165	192	6	1ade67229b50fe20eb392262a3e1ee4306b73290
ToppCell	facs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A PKDREJ CLCA2 ITPRIP RPGR SAMD4A	8.70e-05	167	192	6	961e722442d786ab15d1e490941d2be265a9057a
ToppCell	facs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A PKDREJ CLCA2 ITPRIP RPGR SAMD4A	8.70e-05	167	192	6	3760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MTSS1 CARMIL1 FRY AVIL IRAG2 HCK	8.99e-05	168	192	6	8072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell	Tuft-tuft-1\|World / Class top	MYO7A ADGRB2 HEATR6 AVIL IRAG2 HCK	8.99e-05	168	192	6	8ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	IFI44L GPR171 HERC6 UTY DDX39B LCK	8.99e-05	168	192	6	5e721268f0baa51d3f640f7f4c41db769ebef210
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR55 GPR171 WDFY4 SPTBN4 GUCY2C IFT122	9.29e-05	169	192	6	46f0f0de9a0894c454f93032e7a7a800f47c8276
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FANCD2 NCAPG PROZ NCAPD3 APAF1 SCYL2	9.91e-05	171	192	6	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 CD83 ADAM10 ZEB2 FNIP2 DSC2	9.91e-05	171	192	6	b520d4d5620cac08315e4cbb7e796c5e9e233060
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FANCD2 NCAPG PROZ NCAPD3 APAF1 SCYL2	9.91e-05	171	192	6	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 MYO7A CD83 ZEB2 AREL1 HCK	9.91e-05	171	192	6	5e93c76ee60f9d0590ebb140812653a5e1369417
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HCAR2 ABR CD83 IFI44L RNF213 WDFY4	1.02e-04	172	192	6	c8ea80042faf923b08ff03d73100533d521d73ef
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CEACAM3 CD83 ZEB2 PREX1 WDFY4 HCK	1.02e-04	172	192	6	72fbfa890995e47048b47199c170cc7dcd7661f8
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CEACAM3 CD83 ZEB2 PREX1 WDFY4 HCK	1.02e-04	172	192	6	2ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IDI2-AS1 NCAPD3 VWF FHOD1 CD300LG SLC4A5	1.09e-04	174	192	6	42735f6a8e5ec36dd3d35aceea6d37cf3eaa1871
ToppCell	CF-Myeloid-Neutrophil\|Myeloid / Disease state, Lineage and Cell class	HCAR2 CEACAM3 PREX1 ITPRIP ZNF292 RGL4	1.12e-04	175	192	6	8020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITPR1 BST2 UVRAG NPC1 CARMIL1 GRAMD2A	1.16e-04	176	192	6	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITPR1 BST2 UVRAG NPC1 CARMIL1 GRAMD2A	1.16e-04	176	192	6	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	facs-Skin-nan-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRB2 GPR55 GPR171 LCK AVIL IRAG2	1.20e-04	177	192	6	6e45e1a5a894ca2e4ebc5cdb17fdf79e9e188185
ToppCell	facs-Skin-nan-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRB2 GPR55 GPR171 LCK AVIL IRAG2	1.20e-04	177	192	6	17065d37fd41f04f67282bee00365daa185e8355
ToppCell	facs-Skin-nan-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRB2 GPR55 GPR171 LCK AVIL IRAG2	1.20e-04	177	192	6	9ff3a77c5c62c8a950c46ca22cd7bde425b84c9a
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO5C FBXL2 CARMIL1 GRAMD2A SUSD2 FHOD1	1.20e-04	177	192	6	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	3'-Adult-SmallIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD83 ZEB2 PREX1 WDFY4 CD38 IRAG2	1.23e-04	178	192	6	da1695a936dbe3ca9ee3fb28ceb60511c47b35f8
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-B_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD83 ZEB2 PREX1 WDFY4 CD38 IRAG2	1.23e-04	178	192	6	580fc1d45b82010c665a313b2e7a21e0116819ef
ToppCell	droplet-Limb_Muscle-nan-18m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR55 CD83 NCAPG GPR171 WDFY4 HCK	1.23e-04	178	192	6	4523da0901b78cea5654c1d78c65363455e4f745
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA1 CD83 ZEB2 PREX1 FNIP2 HCK	1.23e-04	178	192	6	fbf49766e1504df554856b84c0576c06f3167329
ToppCell	droplet-Marrow-nan-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITPR1 BST2 GPR171 UVRAG NPC1 CARMIL1	1.27e-04	179	192	6	dcaf2191134a586d50ebaf67dcf5b815b54a722b
ToppCell	LPS_only-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR171 PREX1 NLRC3 LCK CD38 PAFAH2	1.27e-04	179	192	6	def981e97e3ff9019910c9af3861ca0d08eb0d0f
Disease	colorectal cancer (implicated_via_orthology)	APC2 UVRAG LCK HCK	3.04e-05	30	177	4	DOID:9256 (implicated_via_orthology)
Disease	Dysarthria, Guttural	NPC1 PDE8B	3.58e-05	2	177	2	C1563666
Disease	Dysarthria, Mixed	NPC1 PDE8B	3.58e-05	2	177	2	C0454598
Disease	Dysarthria, Spastic	NPC1 PDE8B	3.58e-05	2	177	2	C0454596
Disease	Dysarthria, Flaccid	NPC1 PDE8B	3.58e-05	2	177	2	C0454597
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	3.58e-05	2	177	2	DOID:0110471 (implicated_via_orthology)
Disease	Dysarthria, Scanning	NPC1 PDE8B	3.58e-05	2	177	2	C0240952
Disease	Dysarthria	NPC1 PDE8B	3.58e-05	2	177	2	C0013362
Disease	microcephaly (implicated_via_orthology)	KATNB1 WDR81 ASPM CIT	3.95e-05	32	177	4	DOID:10907 (implicated_via_orthology)
Disease	coagulation factor measurement	ASPM MCF2L VWF	2.24e-04	20	177	3	EFO_0004634
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	HCAR2 ABCA1 NHLRC2 ADAM10 BIRC6 CARMIL1 SLC22A2 CD300LG	2.76e-04	276	177	8	EFO_0004612, EFO_0020943
Disease	Autosomal Recessive Primary Microcephaly	ASPM NCAPD3 CIT	3.00e-04	22	177	3	C3711387
Disease	renal overload-type gout	SPATA31C1 SPATA31C2	5.28e-04	6	177	2	EFO_0021525
Disease	high density lipoprotein particle size measurement	ABCA1 NHLRC2 ADAM10 UVRAG NISCH CD300LG	5.83e-04	170	177	6	EFO_0008592
Disease	reticulocyte measurement	CCDC91 ABCA1 GLS2 BIRC6 ZEB2 ADCY8 RGL1 PROZ ATP11A PREX1 DDX39B MED12 VWF HECTD4 NISCH PAQR3	6.37e-04	1053	177	16	EFO_0010700
Disease	free cholesterol measurement, high density lipoprotein cholesterol measurement	HCAR2 ABCA1 NHLRC2 ADAM10 UVRAG RABGGTA CARMIL1 CD300LG	6.62e-04	315	177	8	EFO_0004612, EFO_0008591
Disease	Hirschsprung Disease	ZEB2 MED12 CELSR3	8.43e-04	31	177	3	C0019569
Disease	Abnormality of the skeletal system	APC2 ZNF292	9.78e-04	8	177	2	C4021790
Disease	eosinophil cationic protein measurement	SPATA31C1 SPATA31C2	9.78e-04	8	177	2	EFO_0010913
Disease	Congenital Hydrocephalus	WDR81 IFT122	9.78e-04	8	177	2	C0020256
Disease	Fanconi anemia (implicated_via_orthology)	FANCD2 FAN1	9.78e-04	8	177	2	DOID:13636 (implicated_via_orthology)
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	HCAR2 ABCA1 NHLRC2 ADAM10 HECTD4 SLC22A2 CD300LG	1.12e-03	264	177	7	EFO_0008317, EFO_0020944
Disease	aspartate aminotransferase measurement	ABCA1 MYO7A NHLRC2 PTBP1 BIRC6 ITPR1 RGL1 DSTYK CARMIL1 HECTD4 RNF213 SHOC2 WDR41 SAMD4A	1.16e-03	904	177	14	EFO_0004736
Disease	longitudinal alcohol consumption measurement	SPATA31C1 SPATA31C2	1.25e-03	9	177	2	EFO_0007645
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	ABCA1 ADAM10 UVRAG CARMIL1 IFTAP SLC22A2 CD300LG	1.38e-03	274	177	7	EFO_0004530, EFO_0004612
Disease	anti-topoisomerase-I-antibody-positive systemic scleroderma	METTL22 IFT122	1.56e-03	10	177	2	EFO_0008537
Disease	Abnormality of nervous system morphology	APC2 ZNF292	1.56e-03	10	177	2	C4022810
Disease	arrhythmogenic right ventricular cardiomyopathy (is_implicated_in)	RYR2 DSC2	1.56e-03	10	177	2	DOID:0050431 (is_implicated_in)
Disease	reticulocyte count	CCDC91 HCAR2 ABCA1 GLS2 BIRC6 ADCY8 RGL1 DSTYK ATP11A DDX39B MED12 VWF HECTD4 NISCH PAQR3	1.65e-03	1045	177	15	EFO_0007986
Disease	Machado-Joseph disease, age at onset	ATP11A IFTAP	1.90e-03	11	177	2	EFO_0004847, MONDO_0007182
Disease	congestive heart failure (implicated_via_orthology)	IL17A PDE9A RYR2	1.91e-03	41	177	3	DOID:6000 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	ERCC6 APC2 ADAM10 PKDREJ ZEB2 RGL1 PTPN14 OXSM MED12 VWF FRMPD1 SLC22A9 CLCA2 NISCH VPS13B	2.14e-03	1074	177	15	C0006142
Disease	Mitral valve prolapse, response to surgery	AREL1 ZNF592	2.27e-03	12	177	2	EFO_0009951, HP_0001634
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	HCAR2 ABCA1 NHLRC2 ADAM10 SLC22A2 CD300LG	2.45e-03	225	177	6	EFO_0008317, EFO_0020947
Disease	Neurodegeneration with brain iron accumulation	TBCE CRAT	2.67e-03	13	177	2	cv:C2931845
Disease	egg allergy measurement, parental genotype effect measurement	SPATA31C1 SPATA31C2	2.67e-03	13	177	2	EFO_0005939, EFO_0007018
Disease	amino acid measurement	CCDC91 GLS2 RYR2 RGL1 KIF2B VWF CARMIL1 SHOC2 PELP1 GUCY2C NISCH	2.73e-03	678	177	11	EFO_0005134
Disease	cholesteryl ester measurement, high density lipoprotein cholesterol measurement	HCAR2 ABCA1 NHLRC2 ADAM10 RABGGTA NISCH CD300LG	2.87e-03	312	177	7	EFO_0004612, EFO_0010351
Disease	waist-hip ratio	HCAR2 ABCA1 GLS2 BIRC6 ADCY8 DSTYK NPC1 HECTD4 IQCN PDE8B NISCH SLC22A2 CDYL2 RAB15 IFT122 SYMPK	3.01e-03	1226	177	16	EFO_0004343
Disease	total cholesterol measurement, high density lipoprotein cholesterol measurement	HCAR2 ABCA1 NHLRC2 ADAM10 RABGGTA NISCH CD300LG	3.03e-03	315	177	7	EFO_0004574, EFO_0004612
Disease	Colorectal Carcinoma	ABCA1 ERCC6 APC2 TFG ZEB2 ADCY8 NCAPG FBXL2 SLC22A9 GUCY2C ZNF292	3.55e-03	702	177	11	C0009402
Disease	Down syndrome (implicated_via_orthology)	DOP1B DYRK1B	3.57e-03	15	177	2	DOID:14250 (implicated_via_orthology)
Disease	infant head circumference	NHLRC2 PREX1	3.57e-03	15	177	2	EFO_0004577
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	HCAR2 ABCA1 ADAM10 CARMIL1 SLC22A2 CD300LG	3.57e-03	243	177	6	EFO_0004612, EFO_0020944
Disease	immature platelet count	EXOC3L4 VWF CARMIL1 KCTD20	3.87e-03	106	177	4	EFO_0803544
Disease	phosphatidylethanolamine measurement	SYCP2L WDR81 ADAM10 UNC5C WDR41	3.98e-03	173	177	5	EFO_0010228
Disease	Cardiovascular Abnormalities	APC2 ZNF292	4.06e-03	16	177	2	C0243050
Disease	amygdala volume change measurement	SPATA31C1 SPATA31C2	4.06e-03	16	177	2	EFO_0021490
Disease	primary autosomal recessive microcephaly (is_implicated_in)	ASPM NCAPD3	4.06e-03	16	177	2	DOID:0070296 (is_implicated_in)
Disease	Metastatic melanoma	GUCY2C DYRK1B EPHA8	4.21e-03	54	177	3	C0278883
Disease	factor VII measurement	TRPC4AP PROZ MCF2L	4.43e-03	55	177	3	EFO_0004619
Disease	Eye Abnormalities	APAF1 IFT122	4.59e-03	17	177	2	C0015393
Disease	extrahepatic cholestasis (biomarker_via_orthology)	ABCA1 SLC22A2	4.59e-03	17	177	2	DOID:13619 (biomarker_via_orthology)
Disease	response to beta blocker, heart rate	MTSS1 RGL1 IFTAP	4.90e-03	57	177	3	EFO_0004326, EFO_0007766
Disease	immature platelet fraction	EXOC3L4 VWF CARMIL1 KCTD20	5.00e-03	114	177	4	EFO_0009187
Disease	protein Z-dependent protease inhibitor measurement	OTUB2 PROZ	5.14e-03	18	177	2	EFO_0021849
Disease	Drug habituation	CCDC91 PIWIL1 MYO5C SAMD4A	5.16e-03	115	177	4	C0013170
Disease	Drug abuse	CCDC91 PIWIL1 MYO5C SAMD4A	5.16e-03	115	177	4	C0013146
Disease	Prescription Drug Abuse	CCDC91 PIWIL1 MYO5C SAMD4A	5.16e-03	115	177	4	C4316881
Disease	Substance-Related Disorders	CCDC91 PIWIL1 MYO5C SAMD4A	5.16e-03	115	177	4	C0236969
Disease	Drug Use Disorders	CCDC91 PIWIL1 MYO5C SAMD4A	5.16e-03	115	177	4	C0013222
Disease	Drug Dependence	CCDC91 PIWIL1 MYO5C SAMD4A	5.16e-03	115	177	4	C1510472
Disease	Substance Dependence	CCDC91 PIWIL1 MYO5C SAMD4A	5.16e-03	115	177	4	C0038580
Disease	Substance Use Disorders	CCDC91 PIWIL1 MYO5C SAMD4A	5.16e-03	115	177	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	CCDC91 PIWIL1 MYO5C SAMD4A	5.16e-03	115	177	4	C0029231
Disease	heart failure	ZEB2 NPC1 HECTD4 ZNF592 SYMPK	5.27e-03	185	177	5	EFO_0003144
Disease	Substance abuse problem	CCDC91 PIWIL1 MYO5C SAMD4A	5.32e-03	116	177	4	C0740858
Disease	coronary artery disease	ABCA1 TRPC4AP GLS2 ZEB2 DSTYK MCF2L PREX1 DNASE1L1 NPC1 CARMIL1 HECTD4 RNF213 SUSD2 SLC22A2 UNC5C	5.70e-03	1194	177	15	EFO_0001645
Disease	Cannabis use, age at onset	RYR2 ATP2C2	5.72e-03	19	177	2	EFO_0004847, EFO_0007585
Disease	factor VIII measurement, Ischemic stroke	VWF HECTD4	5.72e-03	19	177	2	EFO_0004630, HP_0002140

Protein segments in the cluster

Peptide	Gene	Start	Entry
ELQVLTGSCFKLRTV	ABR	471	Q12979
LIIFTIKANSEACRD	BST2	41	Q10589
IKSERSIILLNFCLS	ADGRB2	961	O60241
TCAVFLRLNSVLKLA	ADCY8	846	P40145
LKAFDSQCQILLTTR	APAF1	251	O14727
LEAKIASCFDSILQL	EXOC3L4	386	Q17RC7
ILDVQSRLFECSNKT	AVIL	611	O75366
LLFVCKVLARIANAT	BIRC6	2351	Q9NR09
KQLVQAFLSCLLTTA	BCL2L10	181	Q9HD36
KFSLCSIRNISQVLE	ADAM10	431	O14672
VIFVKSVQRCIALAQ	DDX39B	291	Q13838
FLETSLEAKNACVLL	BTBD6	231	Q96KE9
ASVLAFLINELACSK	BAZ2B	1211	Q9UIF8
NLVCKVSDFGLSRVL	EPHA5	811	P54756
SLKTLVNASCRVSNL	EPHA5	941	P54756
LQCFLISTLFSRANL	ABCA1	731	O95477
VRSIQKSIFTVCLDA	CRAT	276	P43155
SQQLAKFRSLLCTAE	CA13	221	Q8N1Q1
TLISKQILSDCRAVL	DICER1	296	Q9UPY3
STLIQCLIRNFTRQK	BMS1	96	Q14692
EIQRKFDALRNSCTV	CIT	931	O14578
TLAILIFASDACKNV	DSC2	21	Q02487
KLAQQLCTALLFLAT	DYRK1B	216	Q9Y463
SKLSASQSCVFRELL	ERCC6	1456	Q03468
ISKIFVLIRSCNRSI	ASPM	3296	Q8IZT6
LFNALTCRSQTKLIF	ATP2C2	851	O75185
KVSLRDCRNVSVFLA	ANTKMT	136	Q9BQD7
ELESIISKRNIQFSC	CD38	261	P28907
SACTNLNIKESFTRL	RAB15	151	P59190
IRATISQFNTLTKCV	RGL1	276	Q9NZL6
ACTFALLAALKNVQL	EXOSC8	151	Q96B26
GSTIAILKRTECQFL	GUCY2C	966	P25092
AQLRSVATILKTLCL	IQCN	506	Q9H0B3
LSCLQIASFLLSKQS	ITPRIP	406	Q8IWB1
SRLCIKSLFILSNET	PAQR3	56	Q6TCH7
VLIETQLKACASFIR	C8orf76	256	Q96K31
QLKACASFIRTRLLL	C8orf76	261	Q96K31
LTLIIFTCKFARLQS	CD83	156	Q01151
QNFLKITSTRLLCSR	OXSM	6	Q9NWU1
FNLISEKCDILSILR	OTUB2	6	Q96DC9
CNAVRLTLKDLLFSV	FAM189A1	166	O60320
FLDIVTLCRCAQISK	FBXL2	26	Q9UKC9
LSQSKTIRFLGCEIQ	OR2AK2	101	Q8NG84
SRQRIVCLNSLKASV	KIAA0100	346	Q14667
FAIVLLKQATAVRCL	IFT122	506	Q9HBG6
QLLRAFILKISVCDA	MAD2L2	121	Q9UI95
SLLTAAVIDNIRLCF	NELFA	31	Q9H3P2
CAVARALKVNTALTA	NLRC3	936	Q7RTR2
IRLSKLCVQESASVR	ITPR1	1191	Q14643
LNKISNRTAAIISCL	HCAR2	136	Q8TDS4
DFQCVRSKSLTNLVA	KCTD20	366	Q7Z5Y7
SLLQRCKVQEFVLLS	DOP1B	1376	Q9Y3R5
QLVCRLSKTDIFIIC	IFI44L	111	Q53G44
LELSSENLRTCFKII	IPO11	696	Q9UI26
QTGCTSLKLILQRFL	KATNB1	576	Q9BVA0
LSSRRAALKAFNTCI	OR51D1	241	Q8NGF3
GNCTILFIIKTERSL	OR51G2	46	Q8NGK0
NGVISKISLAISFRC	OR51S1	146	Q8NGJ8
LVERKTISFDACLAQ	OR4K15	86	Q8NH41
AKLRQFSSALIDCLI	MTSS1	91	O43312
RSQLKLRACNSVFTA	PDE8A	206	O60658
SQFKLRACNSVFTAL	PDE8B	261	O95263
CSLQEKFSQTDILIL	PDE9A	331	O76083
ICRQFTKIEAATQRL	C19orf85	56	A0A1B0GUS0
AKEATLLLAVSNLCF	GPR171	266	O14626
LRQLSQAEATDFCKV	HERC6	686	Q8IVU3
QAKVRQGALVCFLST	HEATR6	416	Q6AI08
TRLVLKEDNTFVCTL	KCTD4	206	Q8WVF5
RAANILVSDTLSCKI	LCK	366	P06239
LALRNCFLTSDLNVK	LMTK2	266	Q8IWU2
DSLATFVAILIARQC	MED12	1126	Q93074
DLFRKCVSSNIVLLT	GLS2	131	Q9UI32
CVSSNIVLLTQAFRK	GLS2	136	Q9UI32
SLLVFSNDLRSAQCK	RFPL4B	106	Q6ZWI9
LLELTKQICSFLQTA	HECTD4	2551	Q9Y4D8
NSFRLEKILVSVGCT	IL17A	131	Q16552
VLQVVKLACTDTFAL	OR4D6	181	Q8NGJ1
ILDFICRTLSVSSKN	PELP1	341	Q8IZL8
LVRNSFIVECRAKQS	GPR55	251	Q9Y2T6
LAKSICSQFRTRLNS	DSTYK	581	Q6XUX3
VTACAGQTLQFKLRL	NHLRC2	606	Q8NBF2
ITCFVSLLGLDIKRQ	NPC1	776	O15118
LLEVLKLACSDTFIN	OR7C1	181	O76099
KVARECLSLNNFSSV	RGL4	301	Q8IZJ4
EVLLKTLASCRDTLN	CCDC105	221	Q8IYK2
ALVQCVLRATKESTL	APC2	536	O95996
CSQLVERINVFKTAF	HECTD1	936	Q9ULT8
NILVSASLVCKIADF	HCK	386	P08631
RNKTIFLRTSSQCLE	IFTAP	81	Q86VG3
ICAFNAQRLTLAKVA	DNASE1L1	21	P49184
RKSLICAFAIAFIIS	CABP7	186	Q86V35
FLSCAQKQLSALIAT	CCDC91	421	Q7Z6B0
TKVEQTALLSILNFC	FBXL4	436	Q9UKA2
VKLLARQCTALTAAV	FRMPD1	1551	Q5SYB0
ISCRKIAESSLRVQF	FNIP2	356	Q9P278
NLVCKVSDFGLSRVL	EPHA8	771	P29322
DCTSLNRVLFSANRK	IDI2-AS1	151	Q9NZ38
AFSLLCLLSKVRTQL	CCN5	11	O76076
VELSCKERNILAATF	AREL1	411	O15033
VCFLLLAKTGRTSIQ	CEACAM3	171	P40198
RKVLTSQLQACREAS	MCF2L	941	O15068
IKFLSQCAARVASRA	IRAG2	281	Q12912
VENKVLVLTSCRAFL	CARMIL1	41	Q5VZK9
LVLLCSFQVATRKLS	FRY	746	Q5TBA9
LVQNATFRCILATLL	FHOD1	811	Q9Y613
EFRLLQTANRSKAIC	CELSR3	2466	Q9NYQ7
VVLKVCSCALQRDFL	GRAMD2A	86	Q8IUY3
NLRKLVLFNIRASAC	PRAMEF8	231	Q5VWM4
RKLCLLTTVLINAAA	SLC22A2	176	O15244
QLILLFSRTALTEKC	RYR2	3666	Q92736
LVNKFTLRLVSCVQL	CNTD1	116	Q8N815
FCIARSLSILEQKID	KIF2B	636	Q8N4N8
SCIILLFDVIKSAIR	FANCD2	341	Q9BXW9
NFQQVCTKILTRLFR	MOB3C	146	Q70IA8
TAILALAKETQFRCA	PAFAH2	241	Q99487
ICRKFISINVGNSLI	OTOG	1036	Q6ZRI0
LKNLSFLDLCLISVT	OR14A16	61	Q8NHC5
ADTQIVVCLLSSNRK	PIWIL1	551	Q96J94
TLCSNFLRFIVKLVA	RPGR	341	Q92834
IFRKSRVLTNQSINC	SMG8	311	Q8ND04
LVDAFLKLAKQRSVC	FAN1	496	Q9Y2M0
VNKARTALLTCRTTF	SYDE2	711	Q5VT97
SLSIFCLLKIANFSN	TAS2R19	101	P59542
KALQTVTSFLLLCAI	TAS2R30	226	P59541
KALQTVTSFLLLCAI	TAS2R36	226	P0DTE0
KALQTVTSFLLLCAI	TAS2R46	226	P59540
CSNTSTLAARIKFLQ	UTY	381	O14607
LFLKTNAQLTIRCRQ	UVRAG	306	Q9P2Y5
ASVICRFKDSIQTLG	SUSD2	91	Q9UGT4
SIATLNQLCATKFRV	RIN1	651	Q13671
CFQLEKVSSLSLIQL	SPATA31C2	671	B4DYI2
QLANFCRILAVTISE	TRPC4AP	241	Q8TEL6
ACCTLRIDFSKLVNL	PTBP2	246	Q9UKA9
NKIALELCTFTLAIA	LMBR1L	61	Q6UX01
RVFTQLGSVLKNCDI	NDUFAF7	136	Q7L592
NICKRISLLSFTRFA	SLC22A9	346	Q8IVM8
LFRCELSVEKSTVLQ	RABGGTA	351	Q92696
NDKLVRISIFSVQCL	PKDREJ	1091	Q9NTG1
QLLITFLFTCSQRKP	PKDREJ	1441	Q9NTG1
CLGITLAVDRSNFKT	GANAB	26	Q14697
QAALLRRKSVNTTEC	MEX3C	221	Q5U5Q3
LSKNCFVTRIRLLDS	PTPN14	16	Q15678
SNAVKRTDLTINCLA	SKIDA1	561	Q1XH10
VTQFTTQFLKLRCLQ	PRAMEF20	256	Q5VT98
LVAAVCTFSKQLLAA	PREX1	1331	Q8TCU6
VKLNSLTLARNCFQL	SHOC2	331	Q9UQ13
RIKNACLQTSSLAVR	SCYL2	491	Q6P3W7
VIIRENFVLTTAKCS	PROZ	206	P22891
QSLKSSFEALLQRCS	SEC31B	1076	Q9NQW1
NACTAILSVEKRLNF	METTL22	326	Q9BUU2
RKACVNTAQVLSFLE	SPATA31C1	631	P0DKV0
ACQTAALLQTFRVKD	STRC	1091	Q7RTU9
IKTLLLNFNCSTVVI	SRBD1	581	Q8N5C6
LITQVRSEKCSLQAA	SRP68	516	Q9UHB9
CLVRSFLKSVLEDVN	CDYL2	461	Q8N8U2
ATETQRNEKFCLSRL	CD300LG	281	Q6UXG3
SNAVRFRVCLLINKL	NCAPG	111	Q9BPX3
QRFNITSKICLSILA	NCAPD3	1111	P42695
CNLKFVTLLVALSSE	CLCA2	11	Q9UQC9
ALVLTAKATELFVQC	CHRAC1	41	Q9NRG0
CKLFRRNTQLLELTT	ATP11A	701	P98196
NLRKLVLFNIRASAC	PRAMEF7	231	Q5VXH5
FIKSNCTLRDVLRAS	RNF213	1731	Q63HN8
KQTLSAAAVFNDRLC	RNF213	1971	Q63HN8
LAINKVFCNKASIRI	UHRF1BP1L	56	A0JNW5
LVKCFTLIIQSLQRG	ZWILCH	366	Q9H900
RILTSDVFQDCNKLV	VWF	1061	P04275
LLERKTISFDNCITQ	OR4E2	86	Q8NGC2
FIRLLEKLLTSQCGA	MRPS9	221	P82933
LSKLQEVSLRNCAVS	TBCE	126	Q15813
SSDLSFAIQCSRILK	TFG	71	Q92734
SVSLLLKCIQRFLVD	SYCP2L	81	Q5T4T6
LARACAAQTKATFLK	PSMC3	236	P17980
DQRLLSVLATVKQCT	FAM20B	376	O75063
LSSCVAALVALQAKR	ZNF592	281	Q92610
ISQCFVLKLSDLQSV	NISCH	1221	Q9Y2I1
SALVLCTAFLSRQLQ	ZNF292	271	O60281
FCVLRAISKAQNLSI	WDFY4	241	Q6ZS81
CVALLSDKSAVRFLN	ZNF654	461	Q8IZM8
QCLILVATDASFIIK	SLC4A5	616	Q9BY07
VLLFSIQSKLRACNR	SPTBN4	371	Q9H254
VFCIRGKLNITSLQF	POLR1F	191	Q3B726
SIIKATNLCFAERNV	SYMPK	961	Q92797
KVSSLFREQQSLLDC	ZSWIM3	401	Q96MP5
FLSCTDKLNRRTLLV	VPS13B	1401	Q7Z7G8
ITGVRAINEFCLKSS	SLC30A9	131	Q6PML9
VIAKALKNLTFLCSR	SLC9C2	811	Q5TAH2
ACQTAALLQTFRVKD	STRCP1	1091	A6NGW2
AKACLQSLTTDSRRQ	ZEB2	536	O60315
LACTRRIDTNLNKVS	SDHB	111	P21912
CTLRIDFSKLTSLNV	PTBP1	251	P26599
LRVQFTASACALNLT	ZYG11A	396	Q6WRX3
FSLNTVELVCKLCVR	UNC5C	786	O95185
KRVSQTQARFLQLCL	SAMD4A	31	Q9UPU9
CFQSTVKCLTVLQRL	WDR41	131	Q9HAD4
AQARTILCVKTISLI	WDR81	1391	Q562E7
IETQLKACASFIRTR	ZHX1-C8orf76	226	Q96EF9
KACASFIRTRLLLQF	ZHX1-C8orf76	231	Q96EF9
KDSSCFTVVLNNLRV	VPS13D	2386	Q5THJ4
CFDNLSSSLLVVKLN	LRIG2	186	O94898
EVKCNFRQEASRLTL	MYO5C	1301	Q9NQX4
DFCQNIATRLLLKSS	MYO7A	1926	Q13402
SALFCSQLEIQKLQR	PDE4DIP	346	Q5VU43