Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	steroid 11-beta-monooxygenase activity	CYP11B1 CYP11B2	7.81e-05	2	177	2	GO:0004507
GeneOntologyMolecularFunction	corticosterone 18-monooxygenase activity	CYP11B1 CYP11B2	7.81e-05	2	177	2	GO:0047783
MousePheno	abnormal urine progesterone level	CYP11B1 CYP11B2	7.68e-05	2	123	2	MP:0011545
MousePheno	abnormal urine deoxycorticosterone level	CYP11B1 CYP11B2	7.68e-05	2	123	2	MP:0011552
MousePheno	decreased urine corticosterone level	CYP11B1 CYP11B2	7.68e-05	2	123	2	MP:0011550
MousePheno	increased urine deoxycorticosterone level	CYP11B1 CYP11B2	7.68e-05	2	123	2	MP:0011553
MousePheno	increased urine progesterone level	CYP11B1 CYP11B2	7.68e-05	2	123	2	MP:0011546
Domain	ZnF_C2HC	FAM90A14 FAM90A1 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10	4.84e-07	55	163	7	SM00343
Domain	Znf_CCHC	FAM90A14 FAM90A1 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10	4.84e-07	55	163	7	IPR001878
Domain	FAM198	GASK1B GASK1A	7.57e-05	2	163	2	IPR029207
Domain	Cyt_P450_mitochondrial	CYP11B1 CYP11B2	7.57e-05	2	163	2	IPR002399
Domain	FAM198	GASK1B GASK1A	7.57e-05	2	163	2	PF15051
Domain	calpain_III	CAPN9 CAPN12 CAPN14	1.36e-04	12	163	3	SM00720
Domain	C2_III	CAPN9 CAPN12 CAPN14	1.36e-04	12	163	3	IPR033883
Domain	Calpain_III	CAPN9 CAPN12 CAPN14	1.36e-04	12	163	3	IPR022683
Domain	Calpain_III	CAPN9 CAPN12 CAPN14	1.75e-04	13	163	3	PF01067
Domain	Calpain_domain_III	CAPN9 CAPN12 CAPN14	1.75e-04	13	163	3	IPR022682
Domain	Calpain_cysteine_protease	CAPN9 CAPN12 CAPN14	2.21e-04	14	163	3	IPR022684
Domain	RA	PLEKHH3 RIN1 RADIL RASSF4	2.65e-04	36	163	4	PF00788
Domain	Peptidase_C2	CAPN9 CAPN12 CAPN14	2.75e-04	15	163	3	PF00648
Domain	CysPc	CAPN9 CAPN12 CAPN14	2.75e-04	15	163	3	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN9 CAPN12 CAPN14	2.75e-04	15	163	3	IPR001300
Domain	CALPAIN_CAT	CAPN9 CAPN12 CAPN14	2.75e-04	15	163	3	PS50203
Domain	RA_dom	PLEKHH3 RIN1 RADIL RASSF4	4.00e-04	40	163	4	IPR000159
Domain	4_1_CTD	EPB41L3 EPB41L1	4.49e-04	4	163	2	PF05902
Domain	SAB	EPB41L3 EPB41L1	4.49e-04	4	163	2	PF04382
Domain	Band_4.1_C	EPB41L3 EPB41L1	4.49e-04	4	163	2	IPR008379
Domain	SAB_dom	EPB41L3 EPB41L1	4.49e-04	4	163	2	IPR007477
Domain	TF_fork_head_CS_2	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	6.86e-04	46	163	4	IPR030456
Domain	VWA_2	INTS6L INTS6	7.44e-04	5	163	2	PF13519
Domain	BEX	BEX3 BEX4	7.44e-04	5	163	2	IPR007623
Domain	TF_fork_head_CS_1	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	7.45e-04	47	163	4	IPR018122
Domain	FH	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	8.73e-04	49	163	4	SM00339
Domain	FORK_HEAD_1	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	8.73e-04	49	163	4	PS00657
Domain	FORK_HEAD_2	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	8.73e-04	49	163	4	PS00658
Domain	Fork_head_dom	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	8.73e-04	49	163	4	IPR001766
Domain	FORK_HEAD_3	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	8.73e-04	49	163	4	PS50039
Domain	Forkhead	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	8.73e-04	49	163	4	PF00250
Domain	-	MYCBP2 UBR5 HERC2	8.90e-04	22	163	3	2.130.10.30
Domain	RCC1/BLIP-II	MYCBP2 UBR5 HERC2	1.02e-03	23	163	3	IPR009091
Domain	PEROXIDASE_1	MPO EPX	1.11e-03	6	163	2	PS00435
Domain	THIOL_PROTEASE_CYS	CAPN9 CAPN12 CAPN14	1.46e-03	26	163	3	PS00139
Domain	APC_su10/DOC_dom	MYCBP2 HERC2	1.54e-03	7	163	2	IPR004939
Domain	DOC	MYCBP2 HERC2	1.54e-03	7	163	2	PS51284
Domain	ANAPC10	MYCBP2 HERC2	1.54e-03	7	163	2	PF03256
Domain	APC10	MYCBP2 HERC2	1.54e-03	7	163	2	SM01337
Domain	THIOL_PROTEASE_ASN	CAPN9 CAPN12 CAPN14	1.64e-03	27	163	3	PS00640
Domain	THIOL_PROTEASE_HIS	CAPN9 CAPN12 CAPN14	1.64e-03	27	163	3	PS00639
Domain	Pept_cys_AS	CAPN9 CAPN12 CAPN14	1.82e-03	28	163	3	IPR000169
Domain	AC_N	ADCY4 ADCY1	2.05e-03	8	163	2	IPR032628
Domain	Adcy	ADCY4 ADCY1	2.05e-03	8	163	2	IPR030672
Domain	INT_SG_DDX_CT_C	INTS6L INTS6	2.05e-03	8	163	2	PF15300
Domain	INT_SG_DDX_CT_C	INTS6L INTS6	2.05e-03	8	163	2	IPR029307
Domain	AC_N	ADCY4 ADCY1	2.05e-03	8	163	2	PF16214
Pathway	WP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE	ADCY4 ADCY1 ADRA1D ADRA2B	5.73e-06	16	109	4	M39849
Pubmed	Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.	FAM90A14 FAM90A1 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.64e-21	25	184	12	17684299
Pubmed	Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.45e-17	23	184	10	18602769
Pubmed	Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.	FAM90A14 FAM90A1 FAM90A17 FAM90A19 FAM90A22 FAM90A26 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A10	1.37e-09	164	184	11	22967998
Pubmed	Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.13e-08	6	184	4	27092474
Pubmed	The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	5.22e-08	8	184	4	8530406
Pubmed	Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 CHRD	7.46e-08	21	184	5	9449667
Pubmed	An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	9.36e-08	9	184	4	12412011
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA3F MYCBP2 SZT2 ATP13A1 ANKRD9 PIEZO1 NLRX1 HECTD4 KTI12 PLEKHH3 RADIL FAT1 RRS1 KLHL21 USP40 LRP3 LRRC56 OGDHL TNFAIP2 HERC2 MED13 NOTCH1	1.10e-07	1105	184	22	35748872
Pubmed	A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 CHRD	1.54e-07	24	184	5	29992973
Pubmed	A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	5.22e-07	13	184	4	16884697
Pubmed	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	5.22e-07	13	184	4	7957066
Pubmed	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	PGS1 MPV17L2 MRS2 CYP11B1 HDHD5 CYP11B2 NLRX1 RDH14 TARS2 NDUFV1 DARS2 GSR LRPPRC CRLS1 MECR SLC22A4 MRPS34 OGDHL ACSM5	5.48e-07	926	184	19	20877624
Pubmed	Six members of the mouse forkhead gene family are developmentally regulated.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	9.89e-07	15	184	4	7689224
Pubmed	Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	9.89e-07	15	184	4	22045912
Pubmed	Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.31e-06	16	184	4	8861101
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.31e-06	16	184	4	10208738
Pubmed	FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.	FOXD4L6 FOXD4L5 FOXD4L4	1.45e-06	5	184	3	12234674
Pubmed	Functional equivalency between Otx2 and Otx1 in development of the rostral head.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	2.76e-06	19	184	4	9895322
Pubmed	Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.	GDF5-AS1 PGS1 FAM185A MPV17L2 MRS2 CYP11B1 HDHD5 CYP11B2 NLRX1 TARS2 NDUFV1 DARS2 GSR LRPPRC CRLS1 MECR SLC22A4 MRPS34 OGDHL ACSM5	2.84e-06	1136	184	20	34800366
Pubmed	Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	3.44e-06	20	184	4	12812790
Pubmed	EDD, a ubiquitin-protein ligase of the N-end rule pathway, associates with spindle assembly checkpoint components and regulates the mitotic response to nocodazole.	MRS2 UBR5 CDC20	5.02e-06	7	184	3	25833949
Pubmed	Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	5.15e-06	22	184	4	17389379
Pubmed	Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	7.42e-06	24	184	4	11820816
Pubmed	Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.03e-05	26	184	4	15857913
Pubmed	Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.62e-05	29	184	4	22972626
Pubmed	Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension.	CYP11B1 CYP11B2	2.78e-05	2	184	2	23150505
Pubmed	GRAde: a long-read sequencing approach to efficiently identifying the CYP11B1/CYP11B2 chimeric form in patients with glucocorticoid-remediable aldosteronism.	CYP11B1 CYP11B2	2.78e-05	2	184	2	35012455
Pubmed	Role of genetic variation in regulation of aldosterone biosynthesis.	CYP11B1 CYP11B2	2.78e-05	2	184	2	21164264
Pubmed	Uncovering a new role for peroxidase enzymes as drivers of angiogenesis.	MPO EPX	2.78e-05	2	184	2	26386352
Pubmed	Tumorigenic potential of olfactory bulb-derived human adult neural stem cells associates with activation of TERT and NOTCH1.	TERT NOTCH1	2.78e-05	2	184	2	19209236
Pubmed	The alpha and beta chains of human platelet glycoprotein Ib are both transmembrane proteins containing a leucine-rich amino acid sequence.	GP1BA GP1BB	2.78e-05	2	184	2	3353370
Pubmed	The hamster adrenal cytochrome P450C11 has equipotent 11beta-hydroxylase and 19-hydroxylase activities, but no aldosterone synthase activity.	CYP11B1 CYP11B2	2.78e-05	2	184	2	8645611
Pubmed	Expression and localization of cytochrome P450(11beta,aldo) mRNA in the frog brain.	CYP11B1 CYP11B2	2.78e-05	2	184	2	12231255
Pubmed	A de novo unequal cross-over mutation between CYP11B1 and CYP11B2 genes causes familial hyperaldosteronism type I.	CYP11B1 CYP11B2	2.78e-05	2	184	2	20634641
Pubmed	Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase.	CYP11B1 CYP11B2	2.78e-05	2	184	2	1303253
Pubmed	Cognitive flexibility is associated with KIBRA variant and modulated by recent tobacco use.	CLSTN2 WWC1	2.78e-05	2	184	2	19606085
Pubmed	Inflammatory peroxidases promote breast cancer progression in mice via regulation of the tumour microenvironment.	MPO EPX	2.78e-05	2	184	2	28260049
Pubmed	Role of steroid 11 beta-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humans.	CYP11B1 CYP11B2	2.78e-05	2	184	2	1741400
Pubmed	Lysophosphatidic acid induces the migration and invasion of SGC-7901 gastric cancer cells through the LPA2 and Notch signaling pathways.	LPAR2 NOTCH1	2.78e-05	2	184	2	31115486
Pubmed	Effects of intron conversion in the human CYP11B2 gene on its transcription and blood pressure regulation in transgenic mice.	CYP11B1 CYP11B2	2.78e-05	2	184	2	32540969
Pubmed	Inhibition of aldosterone synthase (CYP11B2) by torasemide prevents atrial fibrosis and atrial fibrillation in mice.	CYP11B1 CYP11B2	2.78e-05	2	184	2	26047574
Pubmed	Aldosterone synthase knockout mouse as a model for sodium-induced endothelial sodium channel up-regulation in vascular endothelium.	CYP11B1 CYP11B2	2.78e-05	2	184	2	26324851
Pubmed	Microsatellite polymorphism analysis allows the individual assignment of the rat 11 beta-hydroxylase gene (Cyp11b1) and the rat aldosterone synthase gene (Cyp11b2) to chromosome 7 using rat x mouse somatic cell hybrids and identifies differences between and within various rat strains.	CYP11B1 CYP11B2	2.78e-05	2	184	2	7669222
Pubmed	Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron.	CYP11B1 CYP11B2	2.78e-05	2	184	2	22933298
Pubmed	Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11 beta-hydroxylase.	CYP11B1 CYP11B2	2.78e-05	2	184	2	2783417
Pubmed	Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism.	CYP11B1 CYP11B2	2.78e-05	2	184	2	2256920
Pubmed	Association of DNA polymorphisms within the CYP11B2/CYP11B1 locus and postoperative hypertension risk in the patients with aldosterone-producing adenomas.	CYP11B1 CYP11B2	2.78e-05	2	184	2	20708777
Pubmed	Molecular genetic studies on the biosynthesis of aldosterone in humans.	CYP11B1 CYP11B2	2.78e-05	2	184	2	22217843
Pubmed	Mechanistic study of polychlorinated biphenyl 126-induced CYP11B1 and CYP11B2 up-regulation.	CYP11B1 CYP11B2	2.78e-05	2	184	2	16396990
Pubmed	Decreased thrombotic tendency in mouse models of the Bernard-Soulier syndrome.	GP1BA GP1BB	2.78e-05	2	184	2	17095718
Pubmed	[123 I]Iodometomidate for molecular imaging of adrenocortical cytochrome P450 family 11B enzymes.	CYP11B1 CYP11B2	2.78e-05	2	184	2	18397978
Pubmed	Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2.	CYP11B1 CYP11B2	2.78e-05	2	184	2	1518866
Pubmed	KIBRA and CLSTN2 polymorphisms exert interactive effects on human episodic memory.	CLSTN2 WWC1	2.78e-05	2	184	2	19804789
Pubmed	Role of RIN1 on telomerase activity driven by EGF-Ras mediated signaling in breast cancer.	TERT RIN1	2.78e-05	2	184	2	33069695
Pubmed	Procollagen I-expressing renin cell precursors.	CYP11B1 CYP11B2	2.78e-05	2	184	2	23761669
Pubmed	Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta).	CYP11B1 CYP11B2	2.78e-05	2	184	2	2592361
Pubmed	Role of the intracellular domains of GPIb in controlling the adhesive properties of the platelet GPIb/V/IX complex.	GP1BA GP1BB	2.78e-05	2	184	2	12522011
Pubmed	Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice.	CYP11B1 CYP11B2	2.78e-05	2	184	2	23314847
Pubmed	Effect of variation in CYP11B1 and CYP11B2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects.	CYP11B1 CYP11B2	2.78e-05	2	184	2	17980006
Pubmed	Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.	CYP11B1 CYP11B2	2.78e-05	2	184	2	16984984
Pubmed	Evidence for local aldosterone synthesis in the large intestine of the mouse.	CYP11B1 CYP11B2	2.78e-05	2	184	2	35288482
Pubmed	Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice.	CYP11B1 CYP11B2	2.78e-05	2	184	2	15731365
Pubmed	Hereditary eosinophil peroxidase deficiency: immunochemical and spectroscopic studies and evidence for a compound heterozygosity of the defect.	MPO EPX	2.78e-05	2	184	2	7809065
Pubmed	Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study.	CYP11B1 CYP11B2	2.78e-05	2	184	2	17651452
Pubmed	Expression of CYP11B1 and CYP11B2 in adrenal adenoma correlates with clinical characteristics of primary aldosteronism.	CYP11B1 CYP11B2	2.78e-05	2	184	2	34743356
Pubmed	Biological, clinical features and modelling of heterozygous variants of glycoprotein Ib platelet subunit alpha (GP1BA) and glycoprotein Ib platelet subunit beta (GP1BB) genes responsible for constitutional thrombocytopenia.	GP1BA GP1BB	2.78e-05	2	184	2	36173017
Pubmed	Polymorphisms in CYP11B2 and CYP11B1 genes associated with primary hyperaldosteronism.	CYP11B1 CYP11B2	2.78e-05	2	184	2	20339375
Pubmed	Genetic analyses of the chimeric CYP11B1/CYP11B2 gene in a Korean family with glucocorticoid-remediable aldosteronism.	CYP11B1 CYP11B2	2.78e-05	2	184	2	20808686
Pubmed	Investigating the influence of KIBRA and CLSTN2 genetic polymorphisms on cross-sectional and longitudinal measures of memory performance and hippocampal volume in older individuals.	CLSTN2 WWC1	2.78e-05	2	184	2	26415670
Pubmed	Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets.	CYP11B1 CYP11B2	2.78e-05	2	184	2	21519965
Pubmed	Diagnosis of glucocorticoid-remediable aldosteronism in hypertensive children.	CYP11B1 CYP11B2	2.78e-05	2	184	2	21625068
Pubmed	Genetic screening for glucocorticoid-remediable aldosteronism (GRA): experience of three clinical centres in Poland.	CYP11B1 CYP11B2	2.78e-05	2	184	2	16110193
Pubmed	Chimeric CYP11B2/CYP11B1 causing 11β-hydroxylase deficiency in Chinese patients with congenital adrenal hyperplasia.	CYP11B1 CYP11B2	2.78e-05	2	184	2	26066897
Pubmed	Coding sequence and expression patterns of mouse chordin and mapping of the cognate mouse chrd and human CHRD genes.	CHRD ALG3	2.78e-05	2	184	2	9782094
Pubmed	Lentiviral gene rescue of a Bernard-Soulier mouse model to study platelet glycoprotein Ibβ function.	GP1BA GP1BB	2.78e-05	2	184	2	27148783
Pubmed	Peroxidase enzymes inhibit osteoclast differentiation and bone resorption.	MPO EPX	2.78e-05	2	184	2	27836774
Pubmed	Allelic variation of calsyntenin 2 (CLSTN2) modulates the impact of developmental tobacco smoke exposure on mnemonic processing in adolescents.	CLSTN2 WWC1	2.78e-05	2	184	2	19058786
Pubmed	Cytotoxicity and decreased corticosterone production in adrenocortical Y-1 cells by 3-methylsulfonyl-DDE and structurally related molecules.	CYP11B1 CYP11B2	2.78e-05	2	184	2	18651133
Pubmed	A new presentation of the chimeric CYP11B1/CYP11B2 gene with low prevalence of primary aldosteronism and atypical gene segregation pattern.	CYP11B1 CYP11B2	2.78e-05	2	184	2	22083159
Pubmed	Editorial: polymorphisms in CYP11B genes and 11-hydroxylase activity.	CYP11B1 CYP11B2	2.78e-05	2	184	2	15699546
Pubmed	Cyp11b1 is induced in the murine gonad by luteinizing hormone/human chorionic gonadotropin and involved in the production of 11-ketotestosterone, a major fish androgen: conservation and evolution of the androgen metabolic pathway.	CYP11B1 CYP11B2	2.78e-05	2	184	2	18162527
Pubmed	Chronic activation of adrenal Gq signaling induces Cyp11b2 expression in the zona fasciculata and hyperaldosteronism.	CYP11B1 CYP11B2	2.78e-05	2	184	2	38341019
Pubmed	Interactive effects of KIBRA and CLSTN2 polymorphisms on episodic memory in old-age unipolar depression.	CLSTN2 WWC1	2.78e-05	2	184	2	25080189
Pubmed	Adrenal CYP11B1/2 expression in primary aldosteronism: immunohistochemical analysis using novel monoclonal antibodies.	CYP11B1 CYP11B2	2.78e-05	2	184	2	24837548
Pubmed	Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity.	CYP11B1 CYP11B2	2.78e-05	2	184	2	30046010
Pubmed	Familial and phenotypic associations of the aldosterone Renin ratio.	CYP11B1 CYP11B2	2.78e-05	2	184	2	19820005
Pubmed	Notch-1 promotes the malignant progression of osteosarcoma through the activation of cell division cycle 20.	CDC20 NOTCH1	2.78e-05	2	184	2	33411691
Pubmed	A short history of platelet glycoprotein Ib complex.	GP1BA GP1BB	2.78e-05	2	184	2	17597992
Pubmed	Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.	CYP11B1 CYP11B2	2.78e-05	2	184	2	22622494
Pubmed	The role of memory-related gene polymorphisms, KIBRA and CLSTN2, on replicate memory assessment in the elderly.	CLSTN2 WWC1	2.78e-05	2	184	2	21643791
Pubmed	Mutation analysis of CYP11B1 and CYP11B2 in patients with increased 18-hydroxycortisol production.	CYP11B1 CYP11B2	2.78e-05	2	184	2	15062555
Pubmed	Disturbed homeostasis in sodium-restricted mice heterozygous and homozygous for aldosterone synthase gene disruption.	CYP11B1 CYP11B2	2.78e-05	2	184	2	17075030
Pubmed	Polymorphic variation in the 11beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency.	CYP11B1 CYP11B2	2.78e-05	2	184	2	17075029
Pubmed	CYP11B2-CYP11B1 haplotypes associated with decreased 11 beta-hydroxylase activity.	CYP11B1 CYP11B2	2.78e-05	2	184	2	15507509
Pubmed	Polymorphism of CYP11B2 determines salt sensitivity in Japanese.	CYP11B1 CYP11B2	2.78e-05	2	184	2	17296872
Pubmed	Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase.	CYP11B1 CYP11B2	2.78e-05	2	184	2	18039983
Pubmed	Cyp11b1 null mouse, a model of congenital adrenal hyperplasia.	CYP11B1 CYP11B2	2.78e-05	2	184	2	19029289
Pubmed	Genetic variation at the locus encompassing 11-beta hydroxylase and aldosterone synthase accounts for heritability in cortisol precursor (11-deoxycortisol) urinary metabolite excretion.	CYP11B1 CYP11B2	2.78e-05	2	184	2	15522937
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SPNS1 MRS2 MYCBP2 ATP13A1 PIEZO1 TRIOBP TARS2 EPB41L3 NDUFV1 DARS2 GSR KIF7 LRPPRC UBR5 RRS1 SLC19A1 MRPS34 TMEM131 HERC2 ATP2B4 EPB41L1	4.36e-05	1487	184	21	33957083
Pubmed	A mitochondrial protein compendium elucidates complex I disease biology.	PGS1 MPV17L2 MRS2 CYP11B1 HDHD5 CYP11B2 NLRX1 RDH14 TARS2 NDUFV1 DARS2 GSR LRPPRC CRLS1 MECR SLC22A4 MRPS34	4.53e-05	1047	184	17	18614015
Cytoband	8p23.1	FAM90A14 C8orf74 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.98e-12	154	186	12	8p23.1
Cytoband	Ensembl 112 genes in cytogenetic band chr8p23	FAM90A14 C8orf74 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	2.64e-10	234	186	12	chr8p23
Cytoband	9q21.11	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	6.58e-06	30	186	4	9q21.11
Cytoband	18p11.32	THOC1 EPB41L3 TYMSOS	7.09e-05	20	186	3	18p11.32
Cytoband	Ensembl 112 genes in cytogenetic band chrXq13	FAM236D FAM236B GDPD2 FAM236A FAM236C	5.88e-04	165	186	5	chrXq13
GeneFamily	C2 domain containing\|Calpains	CAPN9 CAPN12 CAPN14	7.12e-05	15	100	3	975
GeneFamily	Cytochrome P450 family 11	CYP11B1 CYP11B2	9.05e-05	3	100	2	1007
GeneFamily	Erythrocyte membrane protein band 4.1\|FERM domain containing	EPB41L3 EPB41L1	1.80e-04	4	100	2	951
GeneFamily	Brain expressed X-linked family	BEX3 BEX4	3.00e-04	5	100	2	1217
GeneFamily	Adrenoceptors	ADRA1D ADRA2B	1.06e-03	9	100	2	169
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY4 ADCY1	1.32e-03	10	100	2	53
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	EPB41L3 PLEKHH3 EPB41L1	2.67e-03	50	100	3	1293
GeneFamily	Integrator complex	INTS6L INTS6	3.03e-03	15	100	2	1366
GeneFamily	Cadherin related	CLSTN2 FAT1	3.90e-03	17	100	2	24
GeneFamily	Aminoacyl tRNA synthetases, Class II	TARS2 DARS2	4.87e-03	19	100	2	132
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CD248 SZT2 PPP1R15A ZSCAN18 CDC20 DNASE1L3	2.07e-06	95	175	6	3d6b97576ce4e7a3e495cbc7246ea8c0b2a386f7
ToppCell	wk_20-22-Hematologic-Myeloid-aDC_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	FOXD4L6 FOXD4L4 HMCN2 FOXD4L3 GPR157 TNFAIP2 RASSF4	6.81e-06	178	175	7	fd2bdb4796e86c8cff2d25f0c730ffea21db8787
ToppCell	Pericytes-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS4 CD248 MRGPRF CLSTN2 ADCY1 KIF7 HMCN2	7.59e-06	181	175	7	35c470988a93381eefa300831aabb813fa1b90bd
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|lymph-node_spleen / Manually curated celltypes from each tissue	ANKRD9 BEX3 RTL8B CTDSPL WWC1 GP1BA GP1BB	8.45e-06	184	175	7	10607d7d92edcbb92d992900086b90b307421cc3
ToppCell	droplet-Thymus-nan-18m-Myeloid-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F FBXL13 CRACR2B HSF5 HPN SLC22A4 WWC1	9.39e-06	187	175	7	ed69e7cbd6fb59363b0e26f24887fc49405397ce
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_progenitor_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE9A FAM221A PIEZO1 CRACR2B TNFAIP2 ALDH1A3 NOTCH1	1.04e-05	190	175	7	0bad41d19dc515e6bc61e699f4d56664cf2e72fd
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ADAM9 GDPD2 EPB41L3 GASK1B PLPP3 NOTCH1 WWC1	1.32e-05	197	175	7	965d5a3f8c9b12cb8a8d3429702ae29ebd8c6122
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial-Astroglia\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ADAM9 GDPD2 EPB41L3 GASK1B PLPP3 NOTCH1 WWC1	1.32e-05	197	175	7	3f088eb29197bc575400d6dafd8083e69e4a149f
ToppCell	mLN-Macrophage-Macrophage\|mLN / Region, Cell class and subclass	EPB41L3 GASK1B LRP3 ACSM5 TNFAIP2 RASSF4 DNASE1L3	1.41e-05	199	175	7	6bbec8450afb30347b07da28401a698fc51a3c53
ToppCell	mLN-(6)_Macrophage-(60)_Macrophage\|mLN / shred on region, Cell_type, and subtype	EPB41L3 GASK1B LRP3 ACSM5 TNFAIP2 RASSF4 DNASE1L3	1.41e-05	199	175	7	1ea28b832c6173b1b58da432aaf21e6cd291561e
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS4 CD248 MRGPRF CHRD PODN ALDH1A3 GASK1A	1.45e-05	200	175	7	14f3fe19b6647b32a5e28d717235741997d8522c
ToppCell	Transverse-Dendritic_cell-cycling_DCs\|Transverse / Region, Cell class and subclass	EPB41L3 ARHGAP11A GASK1B CDC20 RASSF4 DNASE1L3 GASK1A	1.45e-05	200	175	7	f588d8889f351c797963616a3575fa43efd46b9a
ToppCell	Transverse-(5)_Dendritic_cell-(52)_cycling_DCs\|Transverse / shred on region, Cell_type, and subtype	EPB41L3 ARHGAP11A GASK1B CDC20 RASSF4 DNASE1L3 GASK1A	1.45e-05	200	175	7	51e643d48b5e97a0e117b578a6ea7d429c6cdd1e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN9 CD248 CLSTN2 KIF7 RADIL CCDC17	2.86e-05	150	175	6	1270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN9 CD248 CLSTN2 KIF7 RADIL CCDC17	2.86e-05	150	175	6	156118ce1d69522624196410cba18b8354cd0bb4
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIOX1 TRIM29 GPR157 TNFAIP2 RASSF4 DNASE1L3	5.04e-05	166	175	6	75d719617c61409860f298ce91cbe3a0aafa0553
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOXD4L6 TRIM29 FOXD4L4 FOXD4L3 TNFAIP2 RASSF4	5.39e-05	168	175	6	6dd58fd981750da49afd53796f244e1803cce97f
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CAPN9 SEMA3F CRACR2B PLEKHH3 KIF7 ALDH1A3	6.14e-05	172	175	6	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC\|lymph-node_spleen / Manually curated celltypes from each tissue	TRIM29 FOXD4L3 GPR157 SYPL2 TNFAIP2 RASSF4	6.14e-05	172	175	6	1b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F PLPP3 RAPGEF3 CTDSPL DNASE1L3 GP1BA	6.14e-05	172	175	6	a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RADIL BEX4 LPAR2 NPW SNX22 WWC1	6.75e-05	175	175	6	96219e58dcb327fd27190be78193e7a0d611e62b
ToppCell	facs-Marrow-KLS-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO CD320 BEX3 SLC22A4 SYPL2 CDC20	6.75e-05	175	175	6	f60167473be62d0ef86ce3614e63c0d1377e45b9
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RADIL BEX4 LPAR2 NPW SNX22 WWC1	6.75e-05	175	175	6	cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCell	3'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBXL13 LRRC10B CLSTN2 ADCY1 ADRA2B GASK1A	6.97e-05	176	175	6	56e19240f4a7b617a986e3c0854b757394e78251
ToppCell	3'-Adult-LymphNode-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBXL13 LRRC10B CLSTN2 ADCY1 ADRA2B GASK1A	6.97e-05	176	175	6	c88b46fe29ae7606c8880a6ff0ebb85c0dfda8bd
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F PLPP3 RAPGEF3 CTDSPL DNASE1L3 GP1BA	6.97e-05	176	175	6	3494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCell	droplet-Liver-Npc-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F PLPP3 RAPGEF3 CTDSPL DNASE1L3 GP1BA	6.97e-05	176	175	6	d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCell	facs-Thymus-Epithelium-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM185A PPP1R15A KCNB1 ZSCAN18 RASSF4 DNASE1L3	7.19e-05	177	175	6	384f841aa7b2d05815af7885e481f5affc55d897
ToppCell	facs-Thymus-Epithelium-3m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM185A PPP1R15A KCNB1 ZSCAN18 RASSF4 DNASE1L3	7.19e-05	177	175	6	0e9e44119653abfd270e602e5e477a15e774638f
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN12 COL7A1 CLSTN2 SSPOP PLEKHH3 SLC19A1	7.19e-05	177	175	6	8684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN12 COL7A1 CLSTN2 SSPOP PLEKHH3 SLC19A1	7.19e-05	177	175	6	65709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell	wk_15-18-Hematologic-Myeloid-aDC_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 TNFAIP2 RASSF4	7.19e-05	177	175	6	ccf5dc54780d6039a4d062dee88440c011ddc0a3
ToppCell	facs-Thymus-Epithelium-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM185A PPP1R15A KCNB1 ZSCAN18 RASSF4 DNASE1L3	7.19e-05	177	175	6	c2b8a3a149d70f77612759dea34df9e43953c566
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	ADAMTS4 MRGPRF GASK1B CHRD PODN ALDH1A3	7.42e-05	178	175	6	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	facs-GAT-Fat-18m-Endothelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN12 PDE9A CRACR2B STOX1 RAPGEF3 NOTCH1	7.65e-05	179	175	6	d56fa2a0b119d51a8d41b00fbbd7dfddefeb279c
ToppCell	facs-GAT-Fat-18m-Endothelial-endothelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN12 PDE9A CRACR2B STOX1 RAPGEF3 NOTCH1	7.65e-05	179	175	6	e0542694fa79d67f67be6f85b4fa6d18f7523253
ToppCell	390C-Lymphocytic-ILC-ILC-1\|390C / Donor, Lineage, Cell class and subclass (all cells)	INTS6L FAM185A NLRX1 LAG3 RDH14 WDR97	7.65e-05	179	175	6	e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCell	facs-GAT-Fat-18m-Endothelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN12 PDE9A CRACR2B STOX1 RAPGEF3 NOTCH1	7.65e-05	179	175	6	83343b68977969c7978acd930a66fc7c44df6a15
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_Myeloid\|bone_marrow / Manually curated celltypes from each tissue	MPO C3orf22 ARHGAP11A BEX3 NPW CDC20	8.38e-05	182	175	6	6745d464c3ff289726aa8164e9a43f407f8e4380
ToppCell	3'_v3-blood-Hematopoietic_Erythro-Mega-Mega-Mast\|blood / Manually curated celltypes from each tissue	SLC5A10 BEX3 CDC20 CTDSPL GP1BA GP1BB	8.38e-05	182	175	6	1923b5669901f828e890416c22d1f1d21a4a2c6a
ToppCell	facs-Skin-Anagen-3m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F GDPD2 GSR BMP3 SLC22A4 QARS1	8.38e-05	182	175	6	22d6f4790950508e8aa27e02a8133af5f53f13c8
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRABD2A ADAMTS4 CD248 ADRA1D FAT1 CTDSPL	8.90e-05	184	175	6	689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	DUSP2 LAG3 ADRA2B GPR157 DNASE1L3 SNX22	8.90e-05	184	175	6	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	droplet-Spleen-nan-21m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 HPN PODN BEX4 TNFAIP2 CDC20	9.17e-05	185	175	6	239cc5184825b3cc98638d4aec0a1de8e508d76c
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CD248 CLSTN2 PLEKHH3 SLC19A1 CTDSPL ATP2B4	9.45e-05	186	175	6	db9b67066fc003c7995ec205d15176bf40c97add
ToppCell	3'_v3-bone_marrow-Hematopoietic_Erythro-Mega\|bone_marrow / Manually curated celltypes from each tissue	TRIM29 NPW CDC20 CTDSPL GP1BA GP1BB	9.45e-05	186	175	6	9ff3c30b1728707bb8f9422941333fe3b2c430f4
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F ADCY4 CRACR2B PLPP3 TNFAIP2 NOTCH1	9.73e-05	187	175	6	f2a0d0829dc88aa93bfb2eebbbc0ef156a9cba84
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDE9A SZT2 STOX1 PPP1R15A KLHL21 ALG3	9.73e-05	187	175	6	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F ADCY4 CRACR2B PLPP3 TNFAIP2 NOTCH1	9.73e-05	187	175	6	fa71f9220b288ed6a1d06f347fec42649aac1f13
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDE9A SZT2 STOX1 PPP1R15A KLHL21 ALG3	9.73e-05	187	175	6	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	facs-Kidney-nan-24m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F ADCY4 CRACR2B PLPP3 TNFAIP2 NOTCH1	1.03e-04	189	175	6	5f8d4b61296c71b32362432a9ce4c1c3aaeb278d
ToppCell	facs-Kidney-nan-24m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F ADCY4 CRACR2B PLPP3 TNFAIP2 NOTCH1	1.03e-04	189	175	6	18f82764b32496e54d1a604a531b261651c5e110
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F ADCY4 CRACR2B PLPP3 TNFAIP2 NOTCH1	1.03e-04	189	175	6	92319bef1f00d6048ba8f9f8b5c6dbb896686b74
ToppCell	facs-Kidney-nan-24m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F ADCY4 CRACR2B PLPP3 TNFAIP2 NOTCH1	1.03e-04	189	175	6	9d02a824bba59ea0660439f0510d843568e9d8c3
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	CAPN12 CLSTN2 FAT1 HPN RASSF4 WWC1	1.03e-04	189	175	6	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	droplet-Spleen-nan-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HPN SLC22A4 BEX4 TNFAIP2 CDC20 ATP2B4	1.06e-04	190	175	6	a273fc119baebc11020009c923beafeebb6428c9
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GDPD2 EPB41L3 TRIM29 FAT1 HPN WWC1	1.06e-04	190	175	6	47e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GDPD2 EPB41L3 TRIM29 FAT1 HPN WWC1	1.06e-04	190	175	6	261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADCY4 PPP1R15A GASK1B KCNB1 PLPP3 TNFAIP2	1.06e-04	190	175	6	e1b721bb74561fe51c53328a0394c9954e489049
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBXL13 CD248 FAT1 LRP3 CHRD PODN	1.09e-04	191	175	6	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	P07-Endothelial-large_vessel_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADCY4 PPP1R15A GASK1B KCNB1 TNFAIP2 NOTCH1	1.09e-04	191	175	6	d162917816dd2e4767c97447c1cddae9397713ab
ToppCell	facs-Skin-Anagen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F GDPD2 GSR BMP3 SLC22A4 QARS1	1.12e-04	192	175	6	ec1fd2fb6e71f87189d66261909a84e2be63cacb
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS4 CLSTN2 PLPP3 PODN TNFAIP2 ALDH1A3	1.12e-04	192	175	6	d7faa993f68e530ad55185505384ae155d36c222
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD248 MRGPRF FAM43B PLPP3 PODN GASK1A	1.12e-04	192	175	6	b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACR2B KCNB1 PLPP3 CTDSPL DNASE1L3 NOTCH1	1.19e-04	194	175	6	c8b9551b93a5aed62154b487db90130604a6125c
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MRGPRF CLSTN2 ADCY1 NPW ALDH1A3 EPB41L1	1.19e-04	194	175	6	69362e13158033de44f90f3773db6c0f27de8cb3
ToppCell	COPD-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	ADAMTS4 EPB41L3 GASK1B LRPPRC KCNB1 PLPP3	1.19e-04	194	175	6	8dcde77767b23e75360adb316cdccf56a00e3726
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS4 CLSTN2 PLPP3 PODN TNFAIP2 ALDH1A3	1.22e-04	195	175	6	fc43cd295f2cc3f6e9442232e028944f011c82cc
ToppCell	(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells\|World / Stress and Cell class	ADCY4 PIEZO1 CRACR2B PLPP3 DNASE1L3 NOTCH1	1.22e-04	195	175	6	6b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCell	facs-Marrow-KLS-3m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO CD320 RRS1 SLC19A1 SLC22A4 CDC20	1.26e-04	196	175	6	c5adc95df9e1d1884a7988336e459a98c5a6769b
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS4 MRGPRF KIF7 HMCN2 ALDH1A3 GASK1A	1.26e-04	196	175	6	614a07334707eafe238d5cb7b080a3ca796a1920
ToppCell	facs-Marrow-KLS-3m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO CD320 RRS1 SLC19A1 SLC22A4 CDC20	1.26e-04	196	175	6	81d1fd63397b2cf893607d828b61a926fa65185f
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS4 CLSTN2 PLPP3 PODN TNFAIP2 ALDH1A3	1.29e-04	197	175	6	ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCell	10x5'-GI_small-bowel-Myeloid_Mac\|GI_small-bowel / Manually curated celltypes from each tissue	PXDC1 EPB41L3 GASK1B TNFAIP2 RASSF4 DNASE1L3	1.33e-04	198	175	6	748db69d3c9774e44c0cc425d937d18b83af8312
ToppCell	distal-3-Endothelial-Bronchial_Vessel_1\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADCY4 ADAMTS4 CD320 GASK1B RAPGEF3 DNASE1L3	1.33e-04	198	175	6	00fdee373eaa43c9ce897f2ba2ecbe94cedea93a
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA3F ADCY4 CD320 GASK1B PLPP3 RAPGEF3	1.33e-04	198	175	6	e9e98c20ff7b3f3851db86381550ce7085e2db9e
ToppCell	Sigmoid-Dendritic_cell-cycling_DCs\|Sigmoid / Region, Cell class and subclass	ADAM9 EPB41L3 GASK1B CDC20 RASSF4 DNASE1L3	1.37e-04	199	175	6	bd6f8c0f79e9a94cc0f8c6105d38851463de821c
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac-Intestinal_macrophages\|GI_small-bowel / Manually curated celltypes from each tissue	PXDC1 EPB41L3 GASK1B TNFAIP2 RASSF4 DNASE1L3	1.37e-04	199	175	6	96070b5ffcbab4952970f43b536969ddd2ca5d14
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	MRGPRF CLSTN2 KIF7 RADIL HMCN2 PODN	1.37e-04	199	175	6	07b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Mesothelial-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CD248 MRGPRF RADIL HMCN2 PODN GASK1A	1.37e-04	199	175	6	60a653100aff31f7f96796ff2ec634798bfb4b0d
ToppCell	Sigmoid-(5)_Dendritic_cell-(52)_cycling_DCs\|Sigmoid / shred on region, Cell_type, and subtype	ADAM9 EPB41L3 GASK1B CDC20 RASSF4 DNASE1L3	1.37e-04	199	175	6	8ee78a39729633bcbb3ab17e1dfaca33f38db569
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac\|GI_small-bowel / Manually curated celltypes from each tissue	PXDC1 EPB41L3 GASK1B TNFAIP2 RASSF4 DNASE1L3	1.37e-04	199	175	6	8990a3d69e24cb3aaba9d6def3d0be9ee973436d
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TRABD2A DUSP2 FOXD4L4 FOXD4L3 GPR157 RASSF4	1.37e-04	199	175	6	7b3d4c62b11268c7c1599600d8a7b331287cf21a
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADCY4 ADAMTS4 CD320 GASK1B RAPGEF3 DNASE1L3	1.37e-04	199	175	6	6a7ecc3a68b9cfc49e50abaeb16e2eee3795377e
ToppCell	Biopsy_IPF-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	ADAMTS4 CD248 MRGPRF PLPP3 PODN ALDH1A3	1.40e-04	200	175	6	2c5626ea8fb4b702d4560117e53edf6cfcf1971e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CD248 MRGPRF PLEKHH3 FAT1 CTDSPL GP1BB	1.40e-04	200	175	6	b5b5a32925f225610fe25a021a742d6397162863
ToppCell	Biopsy_IPF-Mesenchymal-Fibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	CD248 MRGPRF PLPP3 CHRD PODN GASK1A	1.40e-04	200	175	6	d8637f1e62d3fb9476dc51e1b1dc2f4b14b5fcd8
ToppCell	Parenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS4 CD248 MRGPRF ADRA1D FAT1 CHRD	1.40e-04	200	175	6	f9bc22ff17bb1c751e6b05bca3f403836f33459a
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	CD248 MRGPRF PLEKHH3 FAT1 CTDSPL GP1BB	1.40e-04	200	175	6	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	Parenchymal-10x5prime-Stromal-Pericyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS4 CD248 MRGPRF ADRA1D FAT1 CHRD	1.40e-04	200	175	6	0a7640db28c708003d5da2d19eb651f6fedfd710
ToppCell	Biopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CD248 MRGPRF FAM43B KIF7 PODN ALDH1A3	1.40e-04	200	175	6	cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCell	distal-mesenchymal-Adventitial_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS4 CD248 FAM43B PODN ALDH1A3 GASK1A	1.40e-04	200	175	6	687cfada2d0977e8985e0a73a5804f84f2ca9c52
ToppCell	Caecum-Dendritic_cell-cycling_DCs\|Caecum / Region, Cell class and subclass	EPB41L3 GASK1B CDC20 RASSF4 DNASE1L3 GASK1A	1.40e-04	200	175	6	608be9bfe74f8d3202aa92b2905452a06f340f76
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD248 MRGPRF FAM43B CHRD PODN GASK1A	1.40e-04	200	175	6	3e6730c9ed7003a4acf501f699a4965a7a50f946
ToppCell	distal-mesenchymal-Adventitial_Fibroblast-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS4 CD248 FAM43B PODN ALDH1A3 GASK1A	1.40e-04	200	175	6	56e838787385dd282caadeac24fbb0a706bf7f2b
ToppCell	distal-1-mesenchymal-Adventitial_Fibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS4 CD248 FAM43B PODN ALDH1A3 GASK1A	1.40e-04	200	175	6	738060ed65fa5473fdb39e686f7cdecc059ed92c
ToppCell	Caecum-(5)_Dendritic_cell-(52)_cycling_DCs\|Caecum / shred on region, Cell_type, and subtype	EPB41L3 GASK1B CDC20 RASSF4 DNASE1L3 GASK1A	1.40e-04	200	175	6	3b04d08e9122c23f42f66bc74c06cf24e1693987
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS4 FAM221A MRGPRF CLSTN2 ADCY1 MECR	1.40e-04	200	175	6	a372ef3f9e6ff6e3c3376d6e10182977c5067788
ToppCell	(52)_cycling_DCs\|World / shred on Cell_type and subtype	EPB41L3 GASK1B CDC20 RASSF4 DNASE1L3 GASK1A	1.44e-04	201	175	6	ad2d25d84345fdd593065516a05c5c2b5429eac0
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ADAMTS4 SSPOP HSF5 ANKRD33 OPALIN	1.75e-04	132	175	5	dc6edfa821a1cdc645668b0af5ba5ff80dee10bd
Disease	Glucocorticoid-remediable aldosteronism	CYP11B1 CYP11B2	2.85e-05	2	158	2	C1260386
Disease	adrenal cortical adenoma (is_marker_for)	CYP11B1 CYP11B2	2.85e-05	2	158	2	DOID:0050891 (is_marker_for)
Disease	Bernard-Soulier syndrome (implicated_via_orthology)	GP1BA GP1BB	8.52e-05	3	158	2	DOID:2217 (implicated_via_orthology)
Disease	Bernard-Soulier Syndrome	GP1BA GP1BB	8.52e-05	3	158	2	C0005129
Disease	Deficiency of Platelet Glycoprotein 1b	GP1BA GP1BB	8.52e-05	3	158	2	C2713537
Disease	congenital adrenal hyperplasia (implicated_via_orthology)	CYP11B1 CYP11B2	8.52e-05	3	158	2	DOID:0050811 (implicated_via_orthology)
Disease	BERNARD-SOULIER SYNDROME	GP1BA GP1BB	8.52e-05	3	158	2	231200
Disease	Bernard Soulier syndrome	GP1BA GP1BB	8.52e-05	3	158	2	cv:C0005129
Disease	Barber Say syndrome	GP1BA GP1BB	1.70e-04	4	158	2	C1319466
Disease	Brooke-Spiegler syndrome	GP1BA GP1BB	1.70e-04	4	158	2	C1857941
Disease	Bernard-Soulier syndrome (is_implicated_in)	GP1BA GP1BB	1.70e-04	4	158	2	DOID:2217 (is_implicated_in)
Disease	platelet crit	CAPN12 PGS1 ATP13A1 ANKRD9 TBC1D5 PIEZO1 LEMD2 TARS2 EPX TERT PLPP3 HPN CHRD ATP2B4 GP1BA	1.93e-04	952	158	15	EFO_0007985
Disease	gallbladder carcinoma (is_implicated_in)	TERT UBR5	2.82e-04	5	158	2	DOID:4948 (is_implicated_in)
Disease	primary hyperaldosteronism (is_implicated_in)	CYP11B1 CYP11B2	2.82e-04	5	158	2	DOID:446 (is_implicated_in)
Disease	inflammatory bowel disease (implicated_via_orthology)	EPB41L3 ANKZF1 EPB41L1	3.18e-04	25	158	3	DOID:0050589 (implicated_via_orthology)
Disease	Conn Syndrome	CYP11B1 CYP11B2	4.21e-04	6	158	2	C1384514
Disease	Neonatal Alloimmune Thrombocytopenia	GP1BA GP1BB	4.21e-04	6	158	2	C3853779
Disease	FNAITP	GP1BA GP1BB	4.21e-04	6	158	2	C3854603
Disease	Hyperaldosteronism	CYP11B1 CYP11B2	4.21e-04	6	158	2	C0020428
Disease	protocadherin alpha-7 measurement	CYP11B1 CYP11B2	5.88e-04	7	158	2	EFO_0801973
Disease	protein FAM163B measurement	CYP11B1 CYP11B2	1.00e-03	9	158	2	EFO_0802936
Disease	linguistic error measurement, specific language impairment	RTL1 GPR157	1.25e-03	10	158	2	EFO_0007798, EFO_1001510
Disease	androstenedione measurement	CYP11B1 CYP11B2	1.25e-03	10	158	2	EFO_0007972
Disease	neutrophil count, basophil count	MPO HECTD4 PCDHA2 TERT PLPP3 SLC22A4	1.35e-03	224	158	6	EFO_0004833, EFO_0005090
Disease	cell growth regulator with EF hand domain protein 1 measurement	CYP11B1 CYP11B2	1.52e-03	11	158	2	EFO_0801461
Disease	beta thalassemia (is_marker_for)	TERT GSR	1.52e-03	11	158	2	DOID:12241 (is_marker_for)
Disease	3-hydroxyanthranilate 3,4-dioxygenase measurement	CYP11B1 CYP11B2	1.52e-03	11	158	2	EFO_0021862
Disease	reticulocyte count	SEMA3F PGS1 ANKRD9 PIEZO1 HECTD4 PPP1R15A FAT1 PLPP3 SLC19A1 SLC22A4 TMEM131 ATP2B4 DNMT3A KIF1C	1.53e-03	1045	158	14	EFO_0007986
Disease	spleen volume	HECTD4 TERT KIF1C	1.59e-03	43	158	3	EFO_0600047
Disease	esophagus squamous cell carcinoma (is_implicated_in)	EPB41L3 TERT FAT1	1.81e-03	45	158	3	DOID:3748 (is_implicated_in)
Disease	diabetic angiopathy (is_marker_for)	GSR GP1BA	1.82e-03	12	158	2	DOID:11713 (is_marker_for)
Disease	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	TRIOBP ADCY1	2.14e-03	13	158	2	C1846647
Disease	acute myeloid leukemia (is_marker_for)	TERT GSR DNMT3A	2.32e-03	49	158	3	DOID:9119 (is_marker_for)
Disease	Duchenne muscular dystrophy, disease progression measurement	TBC1D5 CLSTN2 ADCY1	2.46e-03	50	158	3	EFO_0008336, MONDO_0010679
Disease	Childhood Acute Lymphoblastic Leukemia	CYP2C8 SLC19A1 NOTCH1	2.75e-03	52	158	3	C0023452
Disease	cleft lip (is_implicated_in)	KIF7 SLC19A1	2.86e-03	15	158	2	DOID:9296 (is_implicated_in)
Disease	nervous system disorder	CYP2C8 SLC19A1 NOTCH1	2.90e-03	53	158	3	C0027765
Disease	idiopathic scoliosis (implicated_via_orthology)	SSPOP KIF7	3.25e-03	16	158	2	DOID:0060250 (implicated_via_orthology)
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	UBR5 NOTCH1	3.25e-03	16	158	2	C0334634
Disease	Acute myeloid leukemia	TERT DNMT3A	3.68e-03	17	158	2	cv:C0023467
Disease	LEUKEMIA, ACUTE MYELOID	TERT DNMT3A	3.68e-03	17	158	2	601626
Disease	oleoylcarnitine measurement	RDH14 SLC22A4	4.59e-03	19	158	2	EFO_0021043
Disease	Coronary Arteriosclerosis	HECTD4 TERT PLPP3	5.16e-03	65	158	3	C0010054
Disease	Coronary Artery Disease	HECTD4 TERT PLPP3	5.16e-03	65	158	3	C1956346

Protein segments in the cluster

Peptide	Gene	Start	Entry
GAIPLRWRNRARNRE	LINC00114	31	Q6XXX2
TGQDRLLIPRWREAR	LINC00479	31	Q96M42
WRPRLLREGNTVRSF	BMP3	86	P12645
ILLEYQLGRWVPRLR	AGBL3	56	Q8NEM8
QDQRVLSGRWRLPLR	CCDC17	501	Q96LX7
TLRLWRCFELDPARR	CDC20	466	Q12834
QRPQGRERLRRLLNW	C8orf74	16	Q6P047
TYGLLRRREDWPSRL	DNMT3A	591	Q9Y6K1
RRGQARRLAPNFRWA	BEX3	36	Q00994
RRGRVRRLVPNFRWA	BEX4	51	Q9NWD9
RIPLEYGWQRETRIR	BAZ2B	746	Q9UIF8
QRAWQERRLLLREPR	ALG3	26	Q92685
ALFPRRRTFLEAWRA	CD248	36	Q9HCU0
AAVWPYRRLALLRRL	ATP13A1	51	Q9HD20
WRRAARAFRGFLLLL	GSR	16	P00390
SPWRRLDALSRGRLL	ALDH1A3	86	P47895
LFSLWRQSCRRRKLP	CYP2C8	16	P10632
QDFRRAFRRILCRPW	ADRA2B	431	P18089
REQRLQRWTRPLSGL	ADCY4	81	Q8NFM4
SRPGWLNFRELLREA	ACSM5	196	Q6NUN0
FIRPLRDWLSRRFGD	DCP2	231	Q8IU60
NWRPASLEARRFRIK	CLSTN2	756	Q9H4D0
WELKLLSRRFPRQLA	C3orf22	101	Q8N5N4
APWLRIARRALRFVL	C5orf38	56	Q86SI9
PLRVLFRRLENGRWS	FAM90A10	391	A6NDY2
LRRGQILWFRGLNRI	ATP2B4	1086	P23634
LLSVWRPEEGRRSLR	CAPN14	381	A8MX76
ERRRGLWWLVPRLSL	OPALIN	126	Q96PE5
SFDTVWRIRQLLRRP	ANKRD33	236	Q7Z3H0
LLNIAWGLRRPIRLQ	RASSF4	56	Q9H2L5
PFRWDQRLFALVLRL	INTS6L	161	Q5JSJ4
PFRWDQRLFALVLRL	INTS6	161	Q9UL03
PLRVLFRRLENGRWS	FAM90A7	391	A6NKC0
RRGRGAWTRLLSLLL	PCDHA2	6	Q9Y5H9
LWKPREGLSRRFELR	RADIL	146	Q96JH8
PLRVLFRRLENGRWS	FAM90A23	391	A8MXZ1
LRIRASDWGLPYRRE	FAT1	536	Q14517
RLRSRALGPRAWVDL	PODN	486	Q7Z5L7
RDRLRINRFAWPKIL	EPB41L1	311	Q9H4G0
LSRKRRRQHGQLWFP	NOTCH1	1756	P46531
WRRLRRLLSAGQLLF	MPV17L2	6	Q567V2
AAFPRRLWERVRLSK	MAK16	71	Q9BXY0
PRTARLSLEGWFLRQ	LPAR2	91	Q9HBW0
SRNRWDRPLFTLVGL	KTI12	221	Q96EK9
LWRRALRAAAGPLAR	NPW	61	Q8N729
PQWLREDERFRLLLR	WWC1	1031	Q8IX03
ARARPEVGRRLERWL	LEMD2	196	Q8NC56
PLRVLFRRLENGRWS	FAM90A1	391	Q86YD7
RSLFLRFVWGRTRLP	HERC2	4716	O95714
PHLVLSLGRRARVWR	FOXD4L4	301	Q8WXT5
PHLVLSLGRRARVWR	FOXD4L3	301	Q6VB84
WLQAGQPLRASRRLR	HMCN2	4336	Q8NDA2
SWLRAQERLRPLGLL	CD320	251	Q9NPF0
DWPLERLGRVFRSRR	FAM43B	46	Q6ZT52
EWTLQVSPFGRLRAR	FAM185A	66	Q8N0U4
ARPVPWNALLRRRAR	DUSP2	46	Q05923
RLVPLRAWLAGRPER	GP1BB	96	P13224
PLRVLFRRLENGRWS	FAM90A22	391	A8MWA6
PLRVLFRRLENGRWS	FAM90A14	391	P0C7W9
TILRRARPIWYVGRD	OGDHL	961	Q9ULD0
NRDRQRRRSPWLLLA	PGS1	41	Q32NB8
NRLATELRRLNPRWN	EPX	396	P11678
LERKLRSLWRRPFNV	MPO	126	P05164
RDFSINPVTLRRWLF	PDE9A	286	O76083
VLRQLPDTSGRRWRE	NLRP1	136	Q9C000
REPALLRGSWRSRFQ	FAM236A	46	A0A1B0GUQ0
PPQDLLGRRRWLSRN	FAM157C	251	P0CG43
WNFGPLSKPRRELRR	KIF7	1316	Q2M1P5
GLIWRRLLSFLGRQL	MRS2	386	Q9HD23
DPAFRRGRLRWLKQE	KIF1C	931	O43896
RRRLGRLWNRLFHRP	LRP3	601	O75074
LLREVLRPGVLWFLR	MARCHF6	441	O60337
RCLWIEGNFLRRFPR	LRRC10B	116	A6NIK2
RSARWLLRAGAAPRL	LRPPRC	6	P42704
LKRLNAGSWFLERRP	GDPD2	301	Q9HCC8
RQWRPRRFSALEQGI	LAG3	476	P18627
ARLAESRRWRPERIP	TEPSIN	436	Q96N21
PLRVLFRRLENGRWS	FAM90A17	391	P0DV74
RHRRNLAEWFSRLPR	NLRX1	81	Q86UT6
RNRDIIRRSGLLLWQ	HECTD4	306	Q9Y4D8
PLRVLFRRLENGRWS	FAM90A16	391	P0DV73
PLRVLFRRLENGRWS	FAM90A19	391	P0DV76
PERNRVLSRWRVFAG	HPN	206	P05981
PLRVLFRRLENGRWS	FAM90A8	391	A6NJQ4
GFWRSRALPRNSILV	GASK1A	76	Q9UFP1
LWSSRRPRTRRNLLL	GASK1B	26	Q6UWH4
GARRRSPFRYDLWNL	ABT1	131	Q9ULW3
KRPRLWRTLGANALL	ADCY1	206	Q08828
RAQILEILRRRPWAG	ADAMTS4	821	O75173
LGFTKVRLLRLRNPW	CAPN12	271	Q6ZSI9
WRTLDRLPRTRLGKL	KCNB1	46	Q14721
LALRWVRADPPRRAA	KLHL21	201	Q9UJP4
RLRTDPRFVWLIGDQ	DNASE1L3	206	Q13609
RGDPRLWDIPLATRR	ANKZF1	316	Q9H8Y5
LLDRWGVFRARLFRE	CTDSPL	181	O15194
REPALLRGSWRSRFQ	FAM236B	46	A0A1B0GV22
LQWRLAPAAARRVRA	FNDC10	91	F2Z333
WARLQRERPELLGSF	CRACR2B	161	Q8N4Y2
RALRFLLGRLPWRVA	GDF5-AS1	21	Q5U4N7
CRSRLFPRTWDLRQL	IFNL3	71	Q8IZI9
FPRTWDLRQLQVRER	IFNL3	76	Q8IZI9
HALWPDLRSRARRLL	GPR157	36	Q5UAW9
LLNGPEWRFNRLRLN	CYP11B1	131	P15538
DIGPRAEIRRPRLLW	A3GALT2	316	U3KPV4
RFPSGTLRVRWLLLL	ADAM9	6	Q13443
SARQELLGDRPRWQR	ANKRD9	246	Q96BM1
RWRTIKLLLRRGADP	ANKMY1	526	Q9P2S6
LQRWRLNVLRLNFRG	FBXL13	216	Q8NEE6
RQVTVPRAWLLFLRG	GP1BA	586	P07359
NLVPEARGYRLEWRR	COL7A1	436	Q02388
TLWRVRTPARQWRGL	MECR	6	Q9BV79
LLNGPEWRFNRLRLN	CYP11B2	131	P19099
PLRVLFRRLENGRWS	FAM90A20P	391	A6NIJ5
LPLRLQNRLFVSWRS	FAM221A	46	A4D161
REPALLRGSWRSRFQ	FAM236C	46	P0DP71
REPALLRGSWRSRFQ	FAM236D	46	A0A1B0GTK5
FRGQRIELIRIRNPW	CAPN9	266	O14815
PLRVLFRRLENGRWS	FAM90A5P	391	A8MXJ8
AWRNNSVPLRLRDGR	SLC22A4	61	Q9H015
AERWRLRPAALGLRL	CRLS1	46	Q9UJA2
LIYRDRLRINRFAWP	EPB41L3	321	Q9Y2J2
PLRVLFRRLENGRWS	FAM90A24P	391	P0C7X0
ARARAWARLRNPPLA	PPP1R15A	611	O75807
RIRFPDILRVFWLTR	RNF139	231	Q8WU17
SGRRLPVRAWADVRR	MRPS34	46	P82930
RALPPVRNLRWRRAF	RTL1	991	A6NKG5
LLARPLRPAARRWRN	RTL8B	11	Q17RB0
WDDPRLFTLTALRRR	QARS1	511	P47897
FAHRPRSWRELPLRL	TARS2	416	Q9BW92
RSWRELPLRLADFGA	TARS2	421	Q9BW92
RLLVGLRWRRLEEPL	SYPL2	21	Q5VXT5
RHLLLLGRNFLQWRR	SZT2	2606	Q5T011
LVNSPRYRSIRWDGR	HSF5	21	Q4G112
NNRVLRRPSERGRAW	ARHGAP11A	986	Q6P4F7
RFTLLRGIEWLQPQR	RGSL1	1021	A5PLK6
WLSQLYRGLSRPIRR	DARS2	6	Q6PI48
WLSLRSYLKRRGPQR	PHTF2	616	Q8N3S3
RSALFAGNEWRRPII	TRIM29	66	Q14134
LRRSLSLWEQRRLPA	RIN1	606	Q13671
GRLWQRLRDAFPEDR	PXDC1	61	Q5TGL8
LWSPGLAKRRAERAR	PLEKHH3	591	Q7Z736
RISNWFINARRRILP	TGIF2LY	96	Q8IUE0
KWLFQRDPGDRRREI	SEMA3F	636	Q13275
VRRASSAFLLLRWPG	SSPOP	656	A2VEC9
NAWSVRQERRRPLLL	RNF151	166	Q2KHN1
PRWSTDLQSRGRRLR	LRRC56	466	Q8IYG6
RLWEPLRVVFQRALR	MRGPRF	301	Q96AM1
ARFTWRGARLLRPLL	PLPP3	216	O14495
RLLGWSLPARVSVRF	NDUFV1	6	P49821
RLPRSPGRLAWAFRL	PKDREJ	131	Q9NTG1
PLRVLFRRLENGRWS	FAM90A12P	391	A8MX19
PHLVLSLGRRARVWR	FOXD4L5	301	Q5VV16
PHLVLSLGRRARVWR	FOXD4L6	301	Q3SYB3
PLRVLFRRLENGRWS	FAM90A9	391	A6NNJ1
PLRVLFRRLENGRWS	FAM90A13P	391	P0C7W8
LIRRQAERRGWAAPI	HDHD5	291	Q9BXW7
FRQLRELSRQWLRPD	SCAND1	126	P57086
PLRVLFRRLENGRWS	FAM90A26	391	D6RGX4
LRRLWDRVLGPARRW	RNF227	151	A6NIN4
RRVLENRWLGPRITF	MYCBP2	4456	O75592
ALWLAARRFVGPRVQ	RDH14	16	Q9HBH5
LGVWRRDQRPGRREL	MED13	66	Q9UHV7
RRIIVAIDGWPRNSR	DIS3	396	Q9Y2L1
PLRVLFRRLENGRWS	FAM90A15P	391	P0C7V4
SLGVLRWRRPDLLNF	TRIOBP	1766	Q9H2D6
PSSRRRAARLFEWLI	RIOX1	196	Q9H6W3
PSAFREWRLLGPFRR	ADRA1D	491	P25100
AFSWLRQRILPSLLR	C12orf71	216	A8MTZ7
GVWRAVPRLSLRLLR	CHRD	236	Q9H2X0
TRLSNLLREQWPERR	RAPGEF3	501	O95398
TRPRRWLQLWRRGVA	TNFAIP2	181	Q03169
RRRSRFLAWGEPAVL	TAS1R3	556	Q7RTX0
LGRLRARPRSRWDAA	TYMSOS	11	Q8TAI1
IWRRLRPRSGERELL	SLC5A10	396	A0PJK1
ERRARAQPGRALLVW	SLC27A5	121	Q9Y2P5
FRRLEEWLAPVQGLR	REX1BD	56	Q96EN9
QVLRDAWRRRALRPP	STOX1	81	Q6ZVD7
ALWQFRSGGRRLVLR	WDR97	221	A6NE52
LTRWQQFARLKGIRP	RRS1	111	Q15050
IQRRWGLPRRIHESL	SPATA31D1	696	Q6ZQQ2
YLIGLISDRLRRNWP	SPNS1	436	Q9H2V7
RELGDSLRRPQLRLW	SLC19A1	256	P41440
LEAQGIWEPFRRRLS	TMEM131	1141	Q92545
SWDRLARALRRSGRP	TMDD1	126	P0DPE3
SQRRPRLRQFSDLWV	TRABD2A	426	Q86V40
WRETRGELQYRPSRR	TBC1D10B	621	Q4KMP7
KRLPNWRTRGLEQRR	SNX22	66	Q96L94
WLSPDPLFLEQRRVR	ZSCAN18	186	Q8TBC5
LTRRHRQAIARLWPN	PIEZO1	1026	Q92508
GLRWVRLLFGREFPL	TBC1D5	331	Q92609
LRAWTVERKRPGRLL	USP40	1021	Q9NVE5
WRLVQRGDPAAFRAL	TERT	36	O14746
NYGWRALRLLARRSP	THOC1	491	Q96FV9
LGRWRLSLELFGRVF	UBR5	2186	O95071
PLRVLFRRLENGRWS	FAM90A18	391	P0DV75