Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	SETD1A SETD1B KMT2D	1.05e-05	8	116	3	GO:0140945
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	SETD1A SETD1B KMT2D	2.23e-05	10	116	3	GO:0140999
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	SETD1A SETD1B KMT2D	2.03e-04	20	116	3	GO:0042800
GeneOntologyMolecularFunction	UDP-glycosyltransferase activity	B3GNT9 B4GALNT1 B3GALT6 RFNG GXYLT2 B3GAT2	2.72e-04	153	116	6	GO:0008194
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	SETD1A SETD1B KMT5C KMT2D	6.61e-04	68	116	4	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	SETD1A SETD1B KMT5C KMT2D	6.99e-04	69	116	4	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	SETD1A SETD1B KMT5C KMT2D	7.78e-04	71	116	4	GO:0042054
GeneOntologyBiologicalProcess	postsynapse assembly	ABI3 LZTS3 CC2D1A ZDHHC8 ARHGEF15 NLGN2 ARHGAP33	1.06e-06	93	118	7	GO:0099068
GeneOntologyBiologicalProcess	regulation of postsynapse assembly	LZTS3 CC2D1A ZDHHC8 ARHGEF15 ARHGAP33	5.11e-06	44	118	5	GO:0150052
GeneOntologyBiologicalProcess	regulation of synapse assembly	ABI3 LZTS3 IQSEC2 CC2D1A ZDHHC8 ARHGEF15 NLGN2 ARHGAP33	2.15e-05	202	118	8	GO:0051963
GeneOntologyBiologicalProcess	synapse organization	ABI3 LZTS3 IQSEC2 CC2D1A PLXND1 ZDHHC8 ARHGEF15 SSH1 NFATC4 PLXNC1 NLGN2 PALLD ARHGAP33 NOS1AP	3.75e-05	685	118	14	GO:0050808
GeneOntologyBiologicalProcess	synapse assembly	ABI3 LZTS3 IQSEC2 CC2D1A PLXND1 ZDHHC8 ARHGEF15 NLGN2 ARHGAP33	7.07e-05	308	118	9	GO:0007416
GeneOntologyBiologicalProcess	regulation of synapse organization	ABI3 LZTS3 IQSEC2 CC2D1A ZDHHC8 ARHGEF15 NFATC4 PLXNC1 NLGN2 ARHGAP33	7.77e-05	387	118	10	GO:0050807
GeneOntologyBiologicalProcess	postsynapse organization	ABI3 LZTS3 CC2D1A ZDHHC8 ARHGEF15 SSH1 NLGN2 ARHGAP33 NOS1AP	8.00e-05	313	118	9	GO:0099173
GeneOntologyBiologicalProcess	regulation of synapse structure or activity	ABI3 LZTS3 IQSEC2 CC2D1A ZDHHC8 ARHGEF15 NFATC4 PLXNC1 NLGN2 ARHGAP33	9.19e-05	395	118	10	GO:0050803
GeneOntologyBiologicalProcess	negative regulation of synapse maturation	ARHGEF15 NFATC4	9.70e-05	3	118	2	GO:2000297
GeneOntologyBiologicalProcess	cell junction organization	ABI3 LZTS3 IQSEC2 CC2D1A PLXND1 ZDHHC8 ARHGEF15 SSH1 NFATC4 PLXNC1 TJP2 NLGN2 AJUBA PALLD ARHGAP33 NOS1AP	1.36e-04	974	118	16	GO:0034330
GeneOntologyBiologicalProcess	regulation of cellular component biogenesis	ABI3 LZTS3 MCIDAS IQSEC2 CC2D1A ZDHHC8 ARHGEF15 RASIP1 WASH3P PHLDB1 SSH1 TENM1 NLGN2 PPP1R35 AJUBA ARHGAP33 ARAP1 DNM2	1.41e-04	1189	118	18	GO:0044087
Domain	SH3_2	CASKIN2 MAP3K9 MAP3K10 TJP2 MYO15A ARHGAP33	1.50e-05	86	115	6	PF07653
Domain	SH3_2	CASKIN2 MAP3K9 MAP3K10 TJP2 MYO15A ARHGAP33	1.50e-05	86	115	6	IPR011511
Domain	N-SET	SETD1A SETD1B	3.76e-05	2	115	2	PF11764
Domain	N-SET	SETD1A SETD1B	3.76e-05	2	115	2	SM01291
Domain	COMPASS_Set1_N-SET	SETD1A SETD1B	3.76e-05	2	115	2	IPR024657
Domain	Plexin_repeat	SEMA6B PLXND1 MEGF8 PLXNC1	4.29e-05	32	115	4	IPR002165
Domain	PSI	SEMA6B PLXND1 MEGF8 PLXNC1	4.29e-05	32	115	4	PF01437
Domain	SH3	ABI3 PPP1R13L CASKIN2 MAP3K9 MAP3K10 TJP2 MYO15A ARHGAP33	5.76e-05	216	115	8	SM00326
Domain	SH3	ABI3 PPP1R13L CASKIN2 MAP3K9 MAP3K10 TJP2 MYO15A ARHGAP33	5.76e-05	216	115	8	PS50002
Domain	SH3_domain	ABI3 PPP1R13L CASKIN2 MAP3K9 MAP3K10 TJP2 MYO15A ARHGAP33	6.55e-05	220	115	8	IPR001452
Domain	SET	SETD1A SETD1B KMT5C KMT2D	1.16e-04	41	115	4	PF00856
Domain	SH3_9	ABI3 PPP1R13L MAP3K9 MAP3K10 ARHGAP33	1.20e-04	78	115	5	PF14604
Domain	Post-SET_dom	SETD1A SETD1B KMT2D	1.20e-04	16	115	3	IPR003616
Domain	PostSET	SETD1A SETD1B KMT2D	1.20e-04	16	115	3	SM00508
Domain	POST_SET	SETD1A SETD1B KMT2D	1.20e-04	16	115	3	PS50868
Domain	PSI	SEMA6B PLXND1 MEGF8 PLXNC1	1.53e-04	44	115	4	IPR016201
Domain	SET	SETD1A SETD1B KMT5C KMT2D	1.82e-04	46	115	4	SM00317
Domain	PSI	SEMA6B PLXND1 MEGF8 PLXNC1	1.82e-04	46	115	4	SM00423
Domain	Rho_GTPase_activation_prot	PLXND1 GMIP PLXNC1 ARHGAP33 ARAP1	2.11e-04	88	115	5	IPR008936
Domain	MADS_MEF2-like	MEF2B MEF2D	2.24e-04	4	115	2	IPR033896
Domain	MLK1/MLK2/MLK4	MAP3K9 MAP3K10	2.24e-04	4	115	2	IPR016231
Domain	MAP3K10	MAP3K9 MAP3K10	2.24e-04	4	115	2	IPR015785
Domain	SET_dom	SETD1A SETD1B KMT5C KMT2D	2.52e-04	50	115	4	IPR001214
Domain	SET	SETD1A SETD1B KMT5C KMT2D	2.52e-04	50	115	4	PS50280
Domain	RDM_domain_RFPL	RFPL3 RFPL2	3.71e-04	5	115	2	IPR022723
Domain	RDM	RFPL3 RFPL2	3.71e-04	5	115	2	PF11002
Domain	MADS_BOX_1	MEF2B MEF2D	5.55e-04	6	115	2	PS00350
Domain	ITI_HC_C	ITIH4 ITIH6	5.55e-04	6	115	2	IPR010600
Domain	MADS	MEF2B MEF2D	5.55e-04	6	115	2	SM00432
Domain	SRF-TF	MEF2B MEF2D	5.55e-04	6	115	2	PF00319
Domain	MADS_BOX_2	MEF2B MEF2D	5.55e-04	6	115	2	PS50066
Domain	ITI_HC_C	ITIH4 ITIH6	5.55e-04	6	115	2	PF06668
Domain	IPT	PLXND1 NFATC4 PLXNC1	5.97e-04	27	115	3	SM00429
Domain	TF_MADSbox	MEF2B MEF2D	7.74e-04	7	115	2	IPR002100
Domain	Semap_dom	SEMA6B PLXND1 PLXNC1	9.01e-04	31	115	3	IPR001627
Domain	SEMA	SEMA6B PLXND1 PLXNC1	9.01e-04	31	115	3	PS51004
Domain	TIG	PLXND1 NFATC4 PLXNC1	9.01e-04	31	115	3	PF01833
Domain	Sema	SEMA6B PLXND1 PLXNC1	9.01e-04	31	115	3	SM00630
Domain	Sema	SEMA6B PLXND1 PLXNC1	9.01e-04	31	115	3	PF01403
Domain	IPT	PLXND1 NFATC4 PLXNC1	9.90e-04	32	115	3	IPR002909
Domain	VIT	ITIH4 ITIH6	1.03e-03	8	115	2	PF08487
Domain	VIT	ITIH4 ITIH6	1.03e-03	8	115	2	SM00609
Domain	PH_dom-like	IRS4 IQSEC2 RGS3 ARHGEF15 PHLDB1 PHLPP1 ARAP1 DNM2 NOS1AP	1.28e-03	426	115	9	IPR011993
Domain	Plexin_cytopl	PLXND1 PLXNC1	1.32e-03	9	115	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXND1 PLXNC1	1.32e-03	9	115	2	IPR013548
Domain	Plexin	PLXND1 PLXNC1	1.32e-03	9	115	2	IPR031148
Domain	RA	RGL3 RASIP1 ARAP1	1.40e-03	36	115	3	PF00788
Domain	RA	RGL3 RASIP1 ARAP1	1.52e-03	37	115	3	PS50200
Domain	VIT	ITIH4 ITIH6	1.64e-03	10	115	2	PS51468
Domain	VIT	ITIH4 ITIH6	1.64e-03	10	115	2	IPR013694
Domain	-	TENM1 LRP6 HHIPL1	1.77e-03	39	115	3	2.120.10.30
Domain	RA_dom	RGL3 RASIP1 ARAP1	1.90e-03	40	115	3	IPR000159
Domain	Quinoprot_gluc/sorb_DH	EML5 HHIPL1	2.38e-03	12	115	2	IPR011041
Domain	6-blade_b-propeller_TolB-like	TENM1 LRP6 HHIPL1	2.85e-03	46	115	3	IPR011042
Domain	-	IRS4 IQSEC2 RGS3 PHLDB1 PHLPP1 ARAP1 DNM2 NOS1AP	2.90e-03	391	115	8	2.30.29.30
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6B SETD1A SETD1B KMT5C CC2D1A PLXND1 KDM6B MBD6 ZDHHC8 AHDC1 RNF43 KIFC2 MYOF FASN PHLDB1 KMT2D EFNA2 WIZ MROH6 SSH1 MEGF8 DISP2 NLGN2 MMP17 DHX34 ARHGAP33 ARAP1	8.32e-16	1105	120	27	35748872
Pubmed	Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.	SAMD1 DDX17 CBLB PHLDB1 CASKIN2 ARAP1 DNM2	1.02e-07	108	120	7	19531213
Pubmed	New nomenclature for chromatin-modifying enzymes.	SETD1A SETD1B KMT5C KDM6B KMT2D	1.63e-06	57	120	5	18022353
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	IRS4 PPP1R3E IQSEC2 CC2D1A MEF2D PHLDB1 MAP7D1 MEGF8 CASKIN2 MAP3K9 MAP3K10 TJP2 PALLD NOS1AP	1.73e-06	861	120	14	36931259
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	SETD1A SETD1B KMT2D	2.22e-06	8	120	3	23130995
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	SETD1A SETD1B KMT2D	2.22e-06	8	120	3	22266653
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	DDX17 RBM33 IQSEC2 CC2D1A GMIP PPP1R13L MEF2D SPATA2L PHLDB1 MROH6 TJP2 RPRD2 PPP1R35 AJUBA NOS1AP	3.06e-06	1038	120	15	26673895
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	SETD1A SETD1B KMT2D	3.31e-06	9	120	3	22665483
Pubmed	Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.	SETD1A SETD1B KMT2D	8.61e-06	12	120	3	27563068
Pubmed	The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis.	MAP3K9 MAP3K10	1.18e-05	2	120	2	11416147
Pubmed	Transport characteristics of a murine renal Na/Pi-cotransporter.	NUDT19 SLC34A1	1.18e-05	2	120	2	7478940
Pubmed	Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.	MEF2B KMT2D	1.18e-05	2	120	2	21796119
Pubmed	Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains.	MAP3K9 MAP3K10	1.18e-05	2	120	2	8477742
Pubmed	Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2.	MAP3K9 MAP3K10	1.18e-05	2	120	2	8536694
Pubmed	The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation.	SETD1A SETD1B	1.18e-05	2	120	2	24550110
Pubmed	In Vivo and In Vitro Characterization of the RNA Binding Capacity of SETD1A (KMT2F).	SETD1A SETD1B	1.18e-05	2	120	2	38003223
Pubmed	TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.	SEMA6B PLXND1 EFNA2 PLXNC1	2.14e-05	47	120	4	35462405
Pubmed	H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.	SETD1A SETD1B KMT2D	2.17e-05	16	120	3	24368734
Pubmed	WDR82, a key epigenetics-related factor, plays a crucial role in normal early embryonic development in mice.	SETD1A SETD1B	3.53e-05	3	120	2	21123813
Pubmed	Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild type phenotype.	MAP3K9 MAP3K10	3.53e-05	3	120	2	18414056
Pubmed	Molecular insight into the SETD1A/B N-terminal region and its interaction with WDR82.	SETD1A SETD1B	3.53e-05	3	120	2	37030068
Pubmed	Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development.	RFPL3 RFPL2	3.53e-05	3	120	2	18656177
Pubmed	Kdm6b and Pmepa1 as Targets of Bioelectrically and Behaviorally Induced Activin A Signaling.	KDM6B PMEPA1	3.53e-05	3	120	2	26215835
Pubmed	The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers.	SETD1A SETD1B	3.53e-05	3	120	2	33567280
Pubmed	PMEPA1/TMEPAI Is a Unique Tumorigenic Activator of AKT Promoting Proteasomal Degradation of PHLPP1 in Triple-Negative Breast Cancer Cells.	PMEPA1 PHLPP1	3.53e-05	3	120	2	34638419
Pubmed	Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity.	MAP3K9 MAP3K10	3.53e-05	3	120	2	8195146
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	SETD1A SETD1B KMT2D	4.37e-05	20	120	3	29785026
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	DDX17 KDM6B RGS3 MYOF FASN PALLD DNM2	4.64e-05	272	120	7	31010829
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	SETD1A B3GNT9 DDX17 SETD1B TOR2A ADAM15 RC3H1 PLXND1 SSH1 MMP17 DNM2	4.73e-05	730	120	11	34857952
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	SETD1A SAMD1 SETD1B MCIDAS MBD6 AHDC1 KMT2D WIZ FBXO7	5.77e-05	495	120	9	27705803
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	SETD1A SETD1B KMT2D	5.88e-05	22	120	3	26886794
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	LZTS3 IQSEC2 ZDHHC8 PLXNC1 MAP3K10 NLGN2	6.54e-05	197	120	6	36604605
Pubmed	Neurotoxin-induced selective ubiquitination and regulation of MEF2A isoform in neuronal stress response.	MEF2B MEF2D	7.05e-05	4	120	2	22764880
Pubmed	Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2 (MEF2) gene family to human chromosomes 15q26, 19p12, 5q14, and 1q12-q23.	MEF2B MEF2D	7.05e-05	4	120	2	8575763
Pubmed	Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function.	MYOF DNM2	7.05e-05	4	120	2	17702744
Pubmed	MEF2 transcription factors regulate distinct gene programs in mammalian skeletal muscle differentiation.	MEF2B MEF2D	7.05e-05	4	120	2	25416778
Pubmed	Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene.	MEF2B MEF2D	7.05e-05	4	120	2	10207130
Pubmed	Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory.	MEF2B MEF2D	7.05e-05	4	120	2	21531906
Pubmed	Insulin receptor substrate-4 binds to Slingshot-1 phosphatase and promotes cofilin dephosphorylation.	IRS4 SSH1	7.05e-05	4	120	2	25100728
Pubmed	Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation.	MEF2B MEF2D	7.05e-05	4	120	2	7643214
Pubmed	AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance.	PRKAB1 PLIN1	7.05e-05	4	120	2	18390901
Pubmed	Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2.	MEF2B MEF2D	7.05e-05	4	120	2	10531067
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	B3GNT9 B4GALNT1 ADAM15 IKBKG B3GALT6 PLXND1 PMEPA1 GXYLT2 MYOF MEGF8 MICAL2 LRP6 SMPD1 PALLD	7.07e-05	1201	120	14	35696571
Pubmed	The DNA sequence of human chromosome 22.	DVL1P1 DDX17 BPIFC ZDHHC8 FBXO7 RFPL3 RFPL2	8.58e-05	300	120	7	10591208
Pubmed	Semaphorin heterodimerization in cis regulates membrane targeting and neocortical wiring.	SEMA6B PLXND1 PLXNC1	9.83e-05	26	120	3	39152101
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	SAMD1 IRS4 IKBKG RCOR2 FASN MAP7D1 KMT2D WIZ	1.06e-04	418	120	8	34709266
Pubmed	Galpha13 regulates MEF2-dependent gene transcription in endothelial cells: role in angiogenesis.	MEF2B MEF2D	1.17e-04	5	120	2	19093215
Pubmed	Calcineurin initiates skeletal muscle differentiation by activating MEF2 and MyoD.	MEF2B MEF2D	1.17e-04	5	120	2	12694204
Pubmed	Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.	SETD1A SETD1B	1.17e-04	5	120	2	25561738
Pubmed	Duplications on human chromosome 22 reveal a novel Ret Finger Protein-like gene family with sense and endogenous antisense transcripts.	RFPL3 RFPL2	1.17e-04	5	120	2	10508838
Pubmed	T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency.	RC3H1 CBLB	1.17e-04	5	120	2	20668237
Pubmed	Expression of MEF2 genes during human cardiac development.	MEF2B MEF2D	1.17e-04	5	120	2	10458488
Pubmed	Characterization of the murine orthologue of a novel human subtelomeric multigene family.	WASH3P WASH4P	1.17e-04	5	120	2	11701968
Pubmed	Different requirement for Rnd GTPases of R-Ras GAP activity of Plexin-C1 and Plexin-D1.	PLXND1 PLXNC1	1.17e-04	5	120	2	19136556
Pubmed	The MEF2B homologue differentially expressed in mouse embryonal carcinoma cells.	MEF2B MEF2D	1.17e-04	5	120	2	7646512
Pubmed	p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation.	MEF2D KMT2D	1.17e-04	5	120	2	18026121
Pubmed	Absence of MEF2 binding to the A/T-rich element in the muscle creatine kinase (MCK) enhancer correlates with lack of early expression of the MCK gene in embryonic mammalian muscle.	MEF2B MEF2D	1.17e-04	5	120	2	8993831
Pubmed	Regulatory role of MEF2D in serum induction of the c-jun promoter.	MEF2B MEF2D	1.17e-04	5	120	2	7760790
Pubmed	The ret finger protein-like 4 gene, Rfpl4, encodes a putative E3 ubiquitin-protein ligase expressed in adult germ cells.	RFPL3 RFPL2	1.17e-04	5	120	2	11850190
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SETD1A IRS4 CC2D1A FASN KMT2D WIZ TJP2 RPRD2 PALLD	1.26e-04	549	120	9	38280479
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ARHGEF15 MYOF PHLDB1 PHLPP1 RPRD2 ARAP1	1.36e-04	225	120	6	12168954
Pubmed	Large-scale concatenation cDNA sequencing.	DDX17 RFNG AHDC1 RGS3 KIFC2 SPATA2L MAP7D1 PLXNC1 MICAL2	1.63e-04	568	120	9	9110174
Pubmed	Identification and characterization of a novel human PP1 phosphatase complex.	SETD1A SETD1B KMT2D	1.68e-04	31	120	3	20516061
Pubmed	ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles.	RFPL3 RFPL2 NOBOX	1.68e-04	31	120	3	31657143
Pubmed	Human subtelomeric WASH genes encode a new subclass of the WASP family.	WASH3P WASH4P	1.75e-04	6	120	2	18159949
Pubmed	The expression of MEF2 genes is implicated in CNS neuronal differentiation.	MEF2B MEF2D	1.75e-04	6	120	2	9013788
Pubmed	GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Induced Cellular Transformation.	SETD1A KMT2D	1.75e-04	6	120	2	34933446
Pubmed	Atypical recognition consensus of CIN85/SETA/Ruk SH3 domains revealed by target-assisted iterative screening.	CBLB TJP2	1.75e-04	6	120	2	12829691
Pubmed	A "double adaptor" method for improved shotgun library construction.	DDX17 RFNG AHDC1 RGS3 KIFC2 SPATA2L MAP7D1 PLXNC1 MICAL2	1.76e-04	574	120	9	8619474
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	SETD1B KDM6B MBD6 RCOR2 KMT2D	2.21e-04	157	120	5	30186101
Pubmed	CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiation.	SETD1A SETD1B	2.45e-04	7	120	2	19433449
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	YRDC PPP1R13L GXYLT2 PHLDB1 MAP7D1 TJP2 PALLD	2.67e-04	361	120	7	26167880
Pubmed	NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.	RFPL3 RFPL2 NOBOX	2.86e-04	37	120	3	15326356
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	IRS4 RBM33 ZDHHC8 RNF43 CASKIN2 TENM1	3.14e-04	263	120	6	34702444
Pubmed	CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes.	SETD1A SETD1B	3.26e-04	8	120	2	18680430
Pubmed	MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis.	MEF2B MEF2D	3.26e-04	8	120	2	30205047
Pubmed	Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2.	MEF2B MEF2D	3.26e-04	8	120	2	17158926
Pubmed	FBXL6 degrades phosphorylated p53 to promote tumor growth.	IRS4 FASN	3.26e-04	8	120	2	33568778
Pubmed	Genomic structure, mapping, and expression analysis of the mammalian Lunatic, Manic, and Radical fringe genes.	RFNG FASN	3.26e-04	8	120	2	10341080
Pubmed	Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex.	SETD1A SETD1B	3.26e-04	8	120	2	17355966
Pubmed	RFPL4 interacts with oocyte proteins of the ubiquitin-proteasome degradation pathway.	RFPL3 RFPL2	3.26e-04	8	120	2	12525704
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	RBM33 AHDC1 MEF2D KMT2D WIZ RPRD2	3.47e-04	268	120	6	33640491
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	DDX17 CC2D1A PPP1R13L MEF2D FASN TJP2 RPRD2 PALLD	3.70e-04	503	120	8	16964243
Pubmed	Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex.	MAP3K9 MAP3K10	4.18e-04	9	120	2	14504284
Pubmed	Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.	SETD1A KMT2D	4.18e-04	9	120	2	26691508
Pubmed	Human transcription factor protein interaction networks.	SETD1A IRS4 RBM33 RC3H1 IKBKG CC2D1A MBD6 MEF2D MAP7D1 KMT2D WIZ NFATC4 LRP6 RPRD2	4.22e-04	1429	120	14	35140242
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	LZTS3 IQSEC2 KIAA0586 PHLPP1	4.92e-04	105	120	4	9628581
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETD1A PLXND1 KDM6B CASKIN2 RPRD2 HHIPL1 DHX34 ARAP1	5.16e-04	529	120	8	14621295
Pubmed	Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes.	SETD1A SETD1B	5.22e-04	10	120	2	17998332
Pubmed	Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS.	SETD1A SETD1B	5.22e-04	10	120	2	18838538
Pubmed	Myocyte Enhancer Factor 2c Regulates Dendritic Complexity and Connectivity of Cerebellar Purkinje Cells.	MEF2B MEF2D	5.22e-04	10	120	2	30276662
Pubmed	WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1).	IRS4 PHLPP1	5.22e-04	10	120	2	24145035
Pubmed	Maternal vitamin C regulates reprogramming of DNA methylation and germline development.	AMH NOBOX	5.22e-04	10	120	2	31485074
Pubmed	Genome-wide association analysis identifies susceptibility loci for migraine without aura.	MEF2D MMP17	5.22e-04	10	120	2	22683712
Pubmed	A genome annotation-driven approach to cloning the human ORFeome.	DDX17 ZDHHC8 FBXO7 MN1 RFPL3 RFPL2	5.66e-04	294	120	6	15461802
Pubmed	Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis.	AMH TJP2	6.36e-04	11	120	2	26258622
Pubmed	ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.	RNF43 LRP6	6.36e-04	11	120	2	22575959
Pubmed	Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C.	MEF2B MEF2D	6.36e-04	11	120	2	9162005
Pubmed	Human CpG binding protein interacts with MLL1, MLL2 and hSet1 and regulates Hox gene expression.	SETD1A KMT2D	6.36e-04	11	120	2	18082152
Pubmed	PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.	CC2D1A SPATA2L FASN	6.57e-04	49	120	3	31762063
Interaction	TOP3B interactions	NUDT19 SEMA6B SETD1A SETD1B RBM33 KMT5C CC2D1A PLXND1 KDM6B MBD6 ZDHHC8 AHDC1 RNF43 KIFC2 MYOF FASN PHLDB1 KMT2D EFNA2 WIZ MROH6 SSH1 MEGF8 DISP2 NLGN2 MMP17 DHX34 ARHGAP33 ARAP1	5.55e-09	1470	119	29	int:TOP3B
Interaction	SH3RF1 interactions	ADAM15 CBLB RNF43 ARHGEF15 MAP3K9 MAP3K10 DNM2	3.57e-06	108	119	7	int:SH3RF1
Interaction	PRMT2 interactions	SETD1A SAMD1 SETD1B IQSEC2 KDM6B CBLB	1.65e-05	91	119	6	int:PRMT2
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	SEMA6B SAMD1 AMH MEF2B RGL3 TGFBR3L CC2D1A GMIP EFNA2 WIZ PLPPR2 DNM2	1.44e-06	797	121	12	chr19p13
Cytoband	22q12.3	BPIFC RFPL3 RFPL2	9.20e-05	33	121	3	22q12.3
Cytoband	Ensembl 112 genes in cytogenetic band chr22q12	BPIFC FBXO7 MN1 RFPL3 RFPL2	4.13e-04	235	121	5	chr22q12
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1A SETD1B KMT5C KMT2D	1.64e-05	34	82	4	487
GeneFamily	Myocyte enhancer factor 2 proteins\|MADS box family	MEF2B MEF2D	1.21e-04	4	82	2	649
GeneFamily	Beta 3-glycosyltransferases	B3GNT9 B3GALT6 RFNG	1.70e-04	24	82	3	426
GeneFamily	Myocyte enhancer factor 2 proteins\|MADS box family	MEF2B MEF2D	2.01e-04	5	82	2	1086
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	CC2D1A RGS3 C2CD4D	5.76e-04	36	82	3	823
GeneFamily	Plexins	PLXND1 PLXNC1	7.17e-04	9	82	2	683
GeneFamily	Wiskott-Aldrich Syndrome protein family	WASH3P WASH4P	2.34e-03	16	82	2	14
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K9 MAP3K10	5.26e-03	24	82	2	654
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN	RBM33 ADAM15 PPP1R3E IKBKG GMIP LMTK3 MBD6 CBLB ZDHHC8 MEF2D ITIH4 MYOF WASH3P MAP7D1 PPP1R35 ARHGAP33	3.46e-06	905	119	16	M40865
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THSD4 SEMA6B ADAM15 ARHGEF15 RASIP1 SLC34A1 DISP2	3.64e-07	166	121	7	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6B ADAM15 SIDT1 PLXND1 RGS3 ARHGEF15 RASIP1	7.54e-07	185	121	7	602536a3308a848f106adcb0a83530997440c8f4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B ADAM15 ARHGEF15 RASIP1 CASKIN2 MN1	9.67e-07	192	121	7	3259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6B ADAM15 PLXND1 RGS3 ARHGEF15 RASIP1 CASKIN2	1.11e-06	196	121	7	ae46d4b00be92e64e46252dcc156161b171eded4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B ADAM15 PLXND1 ARHGEF15 RASIP1 CASKIN2	1.11e-06	196	121	7	8f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B ADAM15 PLXND1 ARHGEF15 RASIP1 CASKIN2	1.11e-06	196	121	7	48b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B ADAM15 PLXND1 ARHGEF15 RASIP1 CASKIN2	1.11e-06	196	121	7	473980c827443464d08a0be28c53e3536369b12a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Glia_progenitor_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	TGFBR3L SIDT1 PMEPA1 ZDHHC8 MEF2D SPON2 ARAP1	1.27e-06	200	121	7	4b937b1d0179d1d0e51931f35720e205d460a07e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6B SAMD1 YRDC PLXND1 RASIP1 TMDD1	2.86e-06	145	121	6	2eebf2294c53f081d3b0169071388e477a195218
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ABI3 RGS3 SPON2 TENM1 MAP3K10 PALLD	3.22e-06	148	121	6	c240d506151fa90c59f40008c5fb31984c6f6f8f
ToppCell	390C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ABI3 KIAA0586 SIDT1 CC2D1A CASKIN2 SPON2	5.42e-06	162	121	6	45be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCell	390C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ABI3 KIAA0586 SIDT1 CC2D1A CASKIN2 SPON2	5.42e-06	162	121	6	fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FASN MICAL2 HHIPL1 PALLD DNASE1L2	7.39e-06	171	121	6	972fab891135bd755d5526cbc5a963200067b0a6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FASN MICAL2 HHIPL1 PALLD DNASE1L2	7.39e-06	171	121	6	2a77ed79c6f2e700e789c80451a70ecb31639719
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 CBLB MYOF EFNA2 MICAL2 PALLD	8.71e-06	176	121	6	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 CBLB MYOF EFNA2 MICAL2 PALLD	8.71e-06	176	121	6	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABI3 ADAM15 PLXND1 ARHGEF15 RASIP1 PHLDB1	9.90e-06	180	121	6	755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-Late_cap\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ABI3 ADAM15 PLXND1 ARHGEF15 RASIP1 CASKIN2	1.09e-05	183	121	6	3e69cc605f166a1f04e3d077935f7cfd806f1ffd
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABI3 ADAM15 PLXND1 ARHGEF15 RASIP1 CASKIN2	1.12e-05	184	121	6	fa38d6a8709f520a027ad7e3ff783c84187ec467
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|metastatic_Brain / Location, Cell class and cell subclass	SEMA6B RGS3 ARHGEF15 RASIP1 DISP2 NLGN2	1.16e-05	185	121	6	ad52970e88e8947ef256095bd4b40229b912d58a
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6B PLXND1 ARHGEF15 RASIP1 SSH1 MAP3K10	1.19e-05	186	121	6	055cc23c4db9aad2d6c62e62c8e58bfe5047c6b1
ToppCell	facs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA6B PLXND1 ARHGEF15 RASIP1 CASKIN2 TJP2	1.27e-05	188	121	6	ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABI3 ADAM15 PLXND1 ARHGEF15 RASIP1 CASKIN2	1.27e-05	188	121	6	5d166d9e71632edd059ff0a9f66f8763f259d40a
ToppCell	facs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA6B PLXND1 ARHGEF15 RASIP1 CASKIN2 TJP2	1.27e-05	188	121	6	e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCell	facs-Heart-LV-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA6B PLXND1 ARHGEF15 RASIP1 CASKIN2 TJP2	1.27e-05	188	121	6	0fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAM15 PLXND1 RGS3 ARHGEF15 RASIP1 CASKIN2	1.31e-05	189	121	6	db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6B ADAM15 PLXND1 RGS3 ARHGEF15 RASIP1	1.31e-05	189	121	6	9e58411e51019ca59e78d3e737d65d2bcbbea2be
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA6B ABI3 PLXND1 ARHGEF15 RASIP1 CASKIN2	1.31e-05	189	121	6	28b9e96a5206b7fdae9b17daf05c8f5d24b6c5ec
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABI3 ADAM15 PLXND1 ARHGEF15 RASIP1 ITIH6	1.35e-05	190	121	6	d4aefae2d3164db6a9e953c54af0151501e9d1da
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SEMA6B ADAM15 SIDT1 PLXND1 ARHGEF15 RASIP1	1.39e-05	191	121	6	e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6B ADAM15 PLXND1 RGS3 ARHGEF15 RASIP1	1.43e-05	192	121	6	1f35efb0765e05f7f9c881849953bef3965be25a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAM15 SIDT1 PLXND1 ARHGEF15 RASIP1	1.43e-05	192	121	6	56b021c297a21dff357531f21e2464f85186106d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B ADAM15 PLXND1 RASIP1 MN1	1.47e-05	193	121	6	cc355b2ed6510619cad969ae074126d7c8db784d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B ADAM15 PLXND1 RASIP1 CASKIN2	1.47e-05	193	121	6	1f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAM15 PLXND1 ARHGEF15 RASIP1 CASKIN2	1.51e-05	194	121	6	ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SEMA6B ABI3 ADAM15 PLXND1 ARHGEF15 RASIP1	1.51e-05	194	121	6	eb279e0d922de921343f0ae032a809f837d915b3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B ADAM15 SIDT1 PLXND1 RASIP1	1.56e-05	195	121	6	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6B ABI3 ADAM15 PLXND1 ARHGEF15 RASIP1	1.56e-05	195	121	6	f65053811074a7f2ff0368f3a63b88e2a08da1a0
ToppCell	facs-Heart-LA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT9 PMEPA1 GXYLT2 GPR153 SPON2 MN1	1.56e-05	195	121	6	79a6e8e6de040ff07539e8901fc407363a50e355
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ADAM15 RGS3 ARHGEF15 RASIP1 CASKIN2 LRP6	1.56e-05	195	121	6	a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCell	facs-Heart-RA-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA6B PLXND1 RGS3 ARHGEF15 RASIP1 CASKIN2	1.56e-05	195	121	6	30c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCell	facs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT9 PMEPA1 GXYLT2 GPR153 SPON2 MN1	1.61e-05	196	121	6	ad1838dabd043cb140260843e3527d8c7d58850e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B ADAM15 PLXND1 RASIP1 CASKIN2	1.61e-05	196	121	6	e224338490691d92c1f70b57112fabdcc92b06a9
ToppCell	facs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT9 PMEPA1 GXYLT2 GPR153 SPON2 MN1	1.61e-05	196	121	6	cbc15c0769016fe9972445169029bd8d14a7e6ef
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6B ADAM15 PLXND1 RGS3 ARHGEF15 RASIP1	1.65e-05	197	121	6	98e34e8612f111bb667a574de1faaa785d318ca4
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B ADAM15 PLXND1 ARHGEF15 RASIP1	1.65e-05	197	121	6	c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM15 PLXND1 ARHGEF15 RASIP1 PHLPP1 MN1	1.65e-05	197	121	6	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6B ADAM15 PLXND1 ARHGEF15 RASIP1 MN1	1.65e-05	197	121	6	0f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6B ABI3 ADAM15 PLXND1 ARHGEF15 RASIP1	1.65e-05	197	121	6	f4834378d5d31560b4efe5dee0d5b5d11caeb10f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B ADAM15 PLXND1 ARHGEF15 RASIP1	1.65e-05	197	121	6	2844dbcd0a673ed81c99920aa45858651a00736d
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAM15 PLXND1 RGS3 ARHGEF15 RASIP1 C1QTNF5	1.65e-05	197	121	6	15d1e0dffee8f5ba8cee37adfbfa0551a0cd5e15
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6B ADAM15 SIDT1 PLXND1 ARHGEF15 RASIP1	1.70e-05	198	121	6	b027a141ab531d0f5d6a26811a53427e7b0771dd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6B ADAM15 PLXND1 ARHGEF15 RASIP1 CASKIN2	1.75e-05	199	121	6	8b62d43af8b2ebb4c1b2d068d50beaf35728dbe7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6B ADAM15 PLXND1 ARHGEF15 RASIP1 CASKIN2	1.75e-05	199	121	6	da5a88749d859d535daa030d0974485906cc0ba7
ToppCell	facs-Lung-18m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INAFM2 ADAM15 KDM6B ARHGEF15 RASIP1 MAP7D1	1.75e-05	199	121	6	c11e0044d3cc37f6bb26df033ad4448b419addfc
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6B ADAM15 PLXND1 ARHGEF15 RASIP1 CASKIN2	1.80e-05	200	121	6	2e47888e041ec3d265425d1df97b6665c6da889c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6B ADAM15 PLXND1 ARHGEF15 RASIP1 CASKIN2	1.80e-05	200	121	6	50fa0f8a3e490d5941b34e66a10158eba6c909d4
ToppCell	Globus_pallidus\|World / BrainAtlas - Mouse McCarroll V32	DDX17 KMT5C KDM6B MBD6 PHLDB1	2.44e-05	126	121	5	44b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCell	Epithelial-Epithelial-B_(AT1-AT2-progenitors)\|Epithelial / shred on cell class and cell subclass (v4)	SEMA6B SAMD1 B3GNT9 IKBKG GMIP	6.36e-05	154	121	5	770712806e26f73456fb77a81aa4ef8ec78a21ea
ToppCell	LPS-antiTNF-Endothelial-Epi-like-Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TOR2A ADAM15 RGL3 KIFC2 SMPD1	6.96e-05	157	121	5	abfd05ed993b80822739f47a735f154092a23632
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 SIDT1 RNF43 RGS3 HS3ST3B1	7.39e-05	159	121	5	94bc6ab248a8f02ccbc0facd24e0c7e9fda687d2
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CBLB RGS3 MICAL2 GPR153 HS3ST3B1	7.39e-05	159	121	5	d2de9391b00b6c47f5fe28a1bad6da2097107ee0
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CBLB RGS3 MICAL2 GPR153 HS3ST3B1	7.39e-05	159	121	5	da6b7f8039adc19839d6c090a0b3d68fb6445a79
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B RGS3 RASIP1 MN1	9.06e-05	166	121	5	8e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231\|Adult / Lineage, Cell type, age group and donor	THSD4 ARHGEF15 RASIP1 PHLDB1 CLEC2L	9.32e-05	167	121	5	5af9127bae05768a5164d5708a4ad37edca99324
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 GXYLT2 CLEC2L MICAL2 PALLD	1.01e-04	170	121	5	fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 GXYLT2 CLEC2L MICAL2 PALLD	1.01e-04	170	121	5	03044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell	droplet-Heart-4Chambers-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3 PLXND1 RGS3 ARHGEF15 RASIP1	1.10e-04	173	121	5	9a04271c51fae34f547db3206f9ff5857686e45c
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ADAM15 RGS3 ARHGEF15 RASIP1 CASKIN2	1.13e-04	174	121	5	b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell	BAL-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SIDT1 PMEPA1 RCOR2 SPON2 HS3ST3B1	1.13e-04	174	121	5	ab654e87c7eab7f33adc61be7a86da5c4d88008d
ToppCell	BAL-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SIDT1 PMEPA1 RCOR2 SPON2 HS3ST3B1	1.13e-04	174	121	5	d9bccff5258c4277bdd1edbd87e17c327ec125e8
ToppCell	BAL-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SIDT1 PMEPA1 RCOR2 SPON2 HS3ST3B1	1.13e-04	174	121	5	2453419842fd22d066631615403393bfe4449bb8
ToppCell	BAL-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SIDT1 PMEPA1 RCOR2 SPON2 HS3ST3B1	1.16e-04	175	121	5	6d5bdfbe53608e01c3845ecd908ca6d0fecc58f8
ToppCell	BAL-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SIDT1 PMEPA1 RCOR2 SPON2 HS3ST3B1	1.16e-04	175	121	5	6839ee3bb4457d13cb08ca8eb79ae33ddd256783
ToppCell	BAL-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SIDT1 PMEPA1 RCOR2 SPON2 HS3ST3B1	1.16e-04	175	121	5	9d6135e183179968555670abec39dff9da2c3219
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM33 KIAA0586 LMTK3 ARHGEF15 DISP2	1.22e-04	177	121	5	8ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B3GNT9 LZTS3 PMEPA1 GPR153 MN1	1.26e-04	178	121	5	cb9a446c145b1435cfe12a1d4568aed0924a6a20
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABI3 ADAM15 PLXND1 ARHGEF15 RASIP1	1.32e-04	180	121	5	97e0dcb7cfbba60a782824c5e23995058609fcd4
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6B ADAM15 PLXND1 RGS3 ARHGEF15	1.36e-04	181	121	5	9bfd93cf053beaee806cacdffd7abef02f94aec6
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THSD4 PMEPA1 PHLDB1 SPON2 PALLD	1.36e-04	181	121	5	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|(2)_5-FU / Stress and Cell class	B3GNT9 B4GALNT1 PMEPA1 RCOR2 MICAL2	1.36e-04	181	121	5	56ae86072858c156681507aecd1bc6cb0a3372d2
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAM15 PLXND1 RGS3 ARHGEF15 RASIP1	1.39e-04	182	121	5	0346f81bbb1f309f3e9d063b20547d548d09472c
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA6B ADAM15 PLXND1 ARHGEF15 RASIP1	1.39e-04	182	121	5	840427d1c23d60482c943ff006b14007ed44d247
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B PLXND1 ARHGEF15 RASIP1	1.43e-04	183	121	5	dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SEMA6B PLXND1 ARHGEF15 RASIP1	1.43e-04	183	121	5	4759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6B ADAM15 PLXND1 ARHGEF15 RASIP1	1.43e-04	183	121	5	a644258ba90acc62d571623e429d72ffc4b69203
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITIH4 WIZ PLXNC1 HS3ST3B1 AJUBA	1.43e-04	183	121	5	b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCell	droplet-Trachea-nan-3m-Endothelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA6B ABI3 PLXND1 ARHGEF15 RASIP1	1.47e-04	184	121	5	fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCell	droplet-Trachea-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA6B ABI3 PLXND1 ARHGEF15 RASIP1	1.47e-04	184	121	5	ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCell	droplet-Heart-4Chambers-21m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3 PLXND1 RGS3 ARHGEF15 RASIP1	1.47e-04	184	121	5	f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCell	droplet-Trachea-nan-3m-Endothelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA6B ABI3 PLXND1 ARHGEF15 RASIP1	1.47e-04	184	121	5	1d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCell	droplet-Trachea-nan-3m-Endothelial-endothelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA6B ABI3 PLXND1 ARHGEF15 RASIP1	1.47e-04	184	121	5	76caad53d55fff5acca27bf190a6de7b27437d9f
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA6B ABI3 PLXND1 ARHGEF15 RASIP1	1.47e-04	184	121	5	1fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA6B ABI3 PLXND1 ARHGEF15 RASIP1	1.47e-04	184	121	5	2467207aaea307873ab286f89cfc7668a227a694
ToppCell	E12.5-Endothelial-capillary_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ABI3 ADAM15 PLXND1 ARHGEF15 RASIP1	1.51e-04	185	121	5	e005d3c01a908157f780bbc1d53dd2ed814a39d2
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3 ADAM15 ARHGEF15 RASIP1 CASKIN2	1.51e-04	185	121	5	c3105978d971da7d0fad1a717ee29afee5ed6357
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B3GNT9 PMEPA1 GXYLT2 PLIN1 MN1	1.51e-04	185	121	5	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3 ADAM15 ARHGEF15 RASIP1 CASKIN2	1.51e-04	185	121	5	4cfef50aeed5b3000ce5e864a41c13740b8267b1
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABI3 ADAM15 PLXND1 ARHGEF15 RASIP1	1.51e-04	185	121	5	a987dbf6adf533c5f8a0a8a465a6c8e67e0ffcc8
ToppCell	E12.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ABI3 ADAM15 PLXND1 ARHGEF15 RASIP1	1.51e-04	185	121	5	0bccc424d0466f7f82baa00127c733640a2d50fb
Drug	Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A	IQSEC2 SIDT1 AHDC1 RNF43 WIZ MICAL2 GPR153 SMPD1 DHX34 PLPPR2	7.48e-08	197	117	10	3308_DN
Drug	Domperidone maleate; Up 200; 7.4uM; MCF7; HT_HG-U133A	IQSEC2 AHDC1 RNF43 SPATA2L GPR153 SPON2 MAP3K9 PHLPP1 MMP17 ARHGAP33	8.22e-08	199	117	10	2655_UP
Drug	Ethosuximide [77-67-8]; Down 200; 28.4uM; MCF7; HT_HG-U133A	RNF43 MYOF PLXNC1 GPR153 MAP3K9 PHLPP1 TBX10 DHX34 PLPPR2	8.01e-07	196	117	9	2280_DN
Drug	Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A	DDX17 ADAM15 RGS3 MYOF PHLDB1 WIZ PHLPP1 PLPPR2 DNM2	8.01e-07	196	117	9	4826_DN
Drug	Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A	PLXND1 MEF2D WIZ MEGF8 MAP3K9 SMPD1 MMP17 ARHGAP33	6.37e-06	190	117	8	4274_UP
Drug	Levamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; HL60; HG-U133A	SEMA6B AGBL5 RFNG AHDC1 WIZ MAP3K9 DEDD ARAP1	7.71e-06	195	117	8	1410_UP
Drug	Ifenprodil tartrate [23210-58-4]; Up 200; 8.4uM; HL60; HT_HG-U133A	SETD1A LZTS3 KDM6B PPP1R13L RGS3 WIZ DHX34 PLPPR2	8.62e-06	198	117	8	2372_UP
Drug	(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A	SETD1B IQSEC2 RNF43 MEF2D WIZ SMPD1 PLPPR2 ARAP1	8.62e-06	198	117	8	4367_DN
Drug	Gliclazide [21187-98-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A	SEMA6B AMH DDX17 CC2D1A PLXND1 WIZ SLC34A1 GPR153	8.62e-06	198	117	8	5514_UP
Drug	Bupropion hydrochloride [31677-93-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A	DDX17 LZTS3 IQSEC2 CC2D1A MEF2D MYOF PHLDB1 PLPPR2	8.94e-06	199	117	8	6256_UP
Drug	Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; PC3; HT_HG-U133A	SETD1A CC2D1A MEF2D WIZ MEGF8 SMPD1 ARHGAP33	5.97e-05	191	117	7	3811_DN
Drug	Pyrithyldione [77-04-3]; Down 200; 24uM; PC3; HT_HG-U133A	B4GALNT1 SETD1B LZTS3 CC2D1A RGS3 CASKIN2 DNM2	6.37e-05	193	117	7	7153_DN
Drug	Mefenamic acid [61-68-7]; Down 200; 16.6uM; MCF7; HT_HG-U133A	DDX17 LZTS3 PLXND1 AHDC1 SPATA2L CASKIN2 LRP6	6.58e-05	194	117	7	1699_DN
Drug	Ipratropium bromide [22254-24-6]; Down 200; 9.8uM; MCF7; HT_HG-U133A	SETD1A LZTS3 KDM6B SMPD1 DEDD DHX34 PLPPR2	6.80e-05	195	117	7	2762_DN
Drug	Isopropamide iodide [71-81-8]; Down 200; 8.4uM; MCF7; HT_HG-U133A	KDM6B PPP1R13L SPATA2L WIZ LRP6 SMPD1 PLPPR2	6.80e-05	195	117	7	3461_DN
Drug	Tetrandrine [518-34-3]; Down 200; 6.4uM; MCF7; HT_HG-U133A	IQSEC2 WIZ SSH1 LRP6 SMPD1 DHX34 ARAP1	6.80e-05	195	117	7	6082_DN
Drug	Bezafibrate [41859-67-0]; Down 200; 11uM; PC3; HT_HG-U133A	IQSEC2 KDM6B PLXNC1 TENM1 MAP3K9 DEDD DHX34	7.02e-05	196	117	7	6653_DN
Drug	Lisuride (S)(-) [18016-80-3]; Up 200; 11.8uM; HL60; HG-U133A	KDM6B WIZ PRKAB1 TJP2 RPRD2 DEDD ARHGAP33	7.02e-05	196	117	7	2046_UP
Drug	Dicloxacillin sodium salt [13412-64-1]; Down 200; 8.2uM; PC3; HT_HG-U133A	IQSEC2 PLXND1 MEF2D PLXNC1 TENM1 TBX10 DHX34	7.02e-05	196	117	7	6666_DN
Drug	chlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A	SETD1A SIDT1 RFNG RGS3 GPR153 MAP3K10 SMPD1	7.02e-05	196	117	7	1158_UP
Drug	Loxapine succinate [27833-64-3]; Down 200; 9uM; MCF7; HT_HG-U133A	B4GALNT1 LZTS3 KIAA0586 RFNG SSH1 CASKIN2 ARAP1	7.02e-05	196	117	7	1516_DN
Drug	Guaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A	SETD1A IKBKG PHLDB1 SSH1 TBX10 DHX34 PLPPR2	7.25e-05	197	117	7	3431_UP
Drug	0316684-0000 [391209-55-5]; Up 200; 10uM; MCF7; HT_HG-U133A	B4GALNT1 GMIP AHDC1 WIZ GPR153 ARAP1 NOS1AP	7.25e-05	197	117	7	7052_UP
Drug	Alfaxalone [23930-19-0]; Up 200; 12uM; MCF7; HT_HG-U133A	ADAM15 CC2D1A PHLDB1 MEGF8 PLXNC1 MYO15A ARAP1	7.25e-05	197	117	7	6514_UP
Drug	chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A	AMH CC2D1A KDM6B MICAL2 PLPPR2 ARAP1 NOS1AP	7.25e-05	197	117	7	6936_UP
Drug	Oxamniquine [21738-42-1]; Up 200; 14.4uM; MCF7; HT_HG-U133A	THSD4 RNF43 MEF2D MYOF MAP3K9 LRP6 PLPPR2	7.25e-05	197	117	7	7344_UP
Drug	Cefixime [79350-37-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A	SETD1A AMH KDM6B PHLDB1 CASKIN2 PLPPR2 ARHGAP33	7.25e-05	197	117	7	3247_UP
Drug	Condelphine [7633-69-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A	CC2D1A RGS3 MYOF PHLDB1 WIZ ARAP1 DNM2	7.25e-05	197	117	7	3538_DN
Drug	Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; HL60; HT_HG-U133A	SETD1A DDX17 PLXND1 MEF2D SMPD1 DHX34 DNM2	7.49e-05	198	117	7	2333_DN
Drug	Alprostadil [745-65-3]; Down 200; 11.2uM; PC3; HT_HG-U133A	SETD1A AMH MYOF PLXNC1 TBX10 DHX34 ARHGAP33	7.49e-05	198	117	7	4099_DN
Drug	Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; HL60; HT_HG-U133A	SIDT1 RGS3 PLXNC1 TBX10 DHX34 PLPPR2 ARHGAP33	7.49e-05	198	117	7	2549_DN
Drug	S(+)-Terguride [37686-84-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	AMH IQSEC2 RFNG RGS3 LRP6 ARAP1 NOS1AP	7.49e-05	198	117	7	6459_DN
Drug	Flucytosine [2022-85-7]; Down 200; 31uM; MCF7; HT_HG-U133A	AMH ADAM15 PLXNC1 MICAL2 TBX10 PLPPR2 ARHGAP33	7.49e-05	198	117	7	6450_DN
Drug	Alfaxalone [23930-19-0]; Down 200; 12uM; MCF7; HT_HG-U133A	AHDC1 PHLDB1 WIZ PLXNC1 PHLPP1 PLPPR2 ARAP1	7.49e-05	198	117	7	5451_DN
Drug	LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A	SETD1A IQSEC2 KIAA0586 RFNG RGS3 ARAP1 NOS1AP	7.49e-05	198	117	7	6935_UP
Drug	Aceclofenac [89796-99-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A	IQSEC2 CC2D1A WIZ PLXNC1 MAP3K9 TBX10 LRP6	7.49e-05	198	117	7	2281_DN
Drug	Chenodiol [474-25-9]; Down 200; 10.2uM; PC3; HT_HG-U133A	B4GALNT1 CC2D1A GMIP AHDC1 PHLDB1 CASKIN2 TENM1	7.49e-05	198	117	7	7310_DN
Drug	Benzydamine hydrochloride [132-69-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A	ADAM15 CC2D1A RFNG WIZ DEDD PLPPR2 ARAP1	7.49e-05	198	117	7	7169_DN
Drug	Fenspiride hydrochloride [5053-08-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A	IQSEC2 PLXND1 KDM6B RGS3 PHLDB1 DEDD ARHGAP33	7.49e-05	198	117	7	6001_DN
Drug	nordihydroguaiaretic acid; Down 200; 1uM; HL60; HT_HG-U133A	SETD1A SIDT1 AHDC1 MYOF SPATA2L ARHGAP33 ARAP1	7.73e-05	199	117	7	2683_DN
Drug	Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A	RFNG WIZ PLXNC1 SPON2 MMP17 DHX34 PLPPR2	7.73e-05	199	117	7	3891_DN
Drug	Moxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A	B4GALNT1 LZTS3 KIAA0586 KDM6B RFNG PHLDB1 CASKIN2	7.97e-05	200	117	7	1682_DN
Drug	Nalbuphine hydrochloride [23277-43-2]; Down 200; 10.2uM; PC3; HT_HG-U133A	SETD1B LZTS3 KIAA0586 MYOF PRKAB1 DEDD DNM2	7.97e-05	200	117	7	2063_DN
Drug	Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; HL60; HT_HG-U133A	RFNG AHDC1 RGS3 TBX10 LRP6 SMPD1 DHX34	7.97e-05	200	117	7	2988_DN
Drug	Felodipine [72509-76-3]; Up 200; 10.4uM; MCF7; HT_HG-U133A	LZTS3 WIZ PHLPP1 LRP6 SMPD1 ARHGAP33	4.17e-04	187	117	6	5294_UP
Drug	ikarugamycin; Up 200; 2uM; MCF7; HT_HG-U133A_EA	SIDT1 PLXND1 KDM6B PMEPA1 GPR153 ARAP1	4.29e-04	188	117	6	974_UP
Drug	LY 294002; Down 200; 10uM; MCF7; HT_HG-U133A	B4GALNT1 YRDC PLXND1 GMIP MICAL2 DHX34	4.66e-04	191	117	6	6987_DN
Drug	Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A	DDX17 RNF43 MYOF PHLDB1 WIZ MICAL2	4.79e-04	192	117	6	2271_DN
Drug	clozapine; Down 200; 10uM; HL60; HT_HG-U133A	MEF2D LRP6 MYO15A DHX34 PLPPR2 ARAP1	4.79e-04	192	117	6	6188_DN
Drug	PHA-00851261E [724719-49-7]; Down 200; 10uM; PC3; HT_HG-U133A	SETD1A B4GALNT1 GMIP KDM6B AHDC1 CASKIN2	4.79e-04	192	117	6	4330_DN
Drug	Probenecid [57-66-9]; Down 200; 14uM; MCF7; HT_HG-U133A	KIAA0586 RFNG CASKIN2 SMPD1 DHX34 PLPPR2	4.92e-04	193	117	6	2825_DN
Drug	Naltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; MCF7; HT_HG-U133A	SETD1A DDX17 IQSEC2 CC2D1A SPATA2L LRP6	4.92e-04	193	117	6	2209_DN
Drug	geldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A	KIAA0586 SIDT1 RFNG SPATA2L CASKIN2 DHX34	4.92e-04	193	117	6	1653_DN
Drug	indomethacin, USP; Up 200; 20uM; MCF7; HG-U133A	DDX17 LZTS3 PHLDB1 WIZ CASKIN2 PLPPR2	4.92e-04	193	117	6	262_UP
Drug	Methazolamide [554-57-4]; Down 200; 17uM; MCF7; HT_HG-U133A	DDX17 SPATA2L WIZ SMPD1 DEDD DNM2	5.06e-04	194	117	6	3474_DN
Drug	Gallamine triethiodide [65-29-2]; Down 200; 4.4uM; MCF7; HT_HG-U133A	KIAA0586 MYOF WIZ CASKIN2 TBX10 LRP6	5.06e-04	194	117	6	2221_DN
Drug	ICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A	SETD1A IQSEC2 RFNG RNF43 MYOF ARHGAP33	5.06e-04	194	117	6	6955_UP
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	SETD1A MYOF LRP6 MYO15A DHX34 DNM2	5.06e-04	194	117	6	6171_DN
Drug	Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A	DDX17 MYOF PHLDB1 WIZ ARHGAP33 ARAP1	5.06e-04	194	117	6	4804_DN
Drug	radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	KIAA0586 PLXND1 GMIP KDM6B MYOF DEDD	5.20e-04	195	117	6	999_DN
Drug	Ampyrone [83-07-8]; Down 200; 19.6uM; MCF7; HT_HG-U133A	LZTS3 MAP3K9 TBX10 LRP6 SMPD1 PLPPR2	5.20e-04	195	117	6	6845_DN
Drug	Acetylsalicylsalicylic acid [530-75-6]; Down 200; 13.4uM; MCF7; HT_HG-U133A	SETD1A PHLDB1 WIZ TBX10 LRP6 DHX34	5.20e-04	195	117	6	2223_DN
Drug	Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A	ADAM15 AHDC1 PHLDB1 WIZ GPR153 SMPD1	5.20e-04	195	117	6	7404_DN
Drug	Fenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; PC3; HT_HG-U133A	SETD1B IQSEC2 PLXND1 MICAL2 PRKAB1 DEDD	5.20e-04	195	117	6	3714_DN
Drug	Estradiol-17 beta [50-28-2]; Up 200; 14.6uM; MCF7; HT_HG-U133A	IQSEC2 MYOF GPR153 SPON2 LRP6 NOS1AP	5.20e-04	195	117	6	2653_UP
Drug	troglitazone; Down 200; 10uM; HL60; HT_HG-U133A	CC2D1A MEF2D MYOF MEGF8 MYO15A DHX34	5.20e-04	195	117	6	6191_DN
Drug	Benperidol [2062-84-2]; Down 200; 10.4uM; HL60; HT_HG-U133A	ADAM15 SPATA2L LRP6 SMPD1 ARAP1 DNM2	5.20e-04	195	117	6	2475_DN
Drug	Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; MCF7; HT_HG-U133A	MYOF WIZ NFATC4 SPON2 SMPD1 ARAP1	5.20e-04	195	117	6	3378_UP
Drug	Brinzolamide [138890-62-7]; Down 200; 10.4uM; PC3; HT_HG-U133A	B4GALNT1 WIZ MEGF8 PLXNC1 DHX34 ARHGAP33	5.20e-04	195	117	6	6670_DN
Drug	Clofazimine [2030-63-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A	PLXND1 RGS3 GPR153 DHX34 PLPPR2 NOS1AP	5.20e-04	195	117	6	5277_DN
Drug	Pimethixene maleate [13187-06-9]; Up 200; 9.8uM; MCF7; HT_HG-U133A	LZTS3 IQSEC2 MYOF MAP3K9 MYO15A ARAP1	5.20e-04	195	117	6	7468_UP
Drug	Methacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; HL60; HT_HG-U133A	RGS3 MEF2D SPON2 LRP6 SMPD1 PLPPR2	5.20e-04	195	117	6	2901_DN
Drug	Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A	ADAM15 MYOF WIZ GPR153 DHX34 NOS1AP	5.34e-04	196	117	6	5280_DN
Drug	CP-320650-01 [172079-28-6]; Down 200; 1uM; PC3; HT_HG-U133A	IQSEC2 KDM6B PHLDB1 WIZ CASKIN2 PLXNC1	5.34e-04	196	117	6	4560_DN
Drug	Imipramine hydrochloride [113-52-0]; Down 200; 12.6uM; PC3; HT_HG-U133A	DDX17 ADAM15 CC2D1A GMIP SPATA2L DNM2	5.34e-04	196	117	6	1807_DN
Drug	Nystatine [1400-61-9]; Up 200; 4.4uM; MCF7; HT_HG-U133A	AMH DDX17 MEF2D PHLDB1 CASKIN2 GPR153	5.34e-04	196	117	6	4807_UP
Drug	Cotinine (-) [486-56-6]; Down 200; 22.6uM; MCF7; HT_HG-U133A	SETD1A SETD1B RFNG RGS3 LRP6 DHX34	5.34e-04	196	117	6	1511_DN
Drug	Dropropizine (R,S) [17692-31-8]; Down 200; 17uM; MCF7; HT_HG-U133A	KIAA0586 CC2D1A PLXND1 RGS3 PLPPR2 DNM2	5.34e-04	196	117	6	7429_DN
Drug	prednisolone; Down 200; 1uM; MCF7; HG-U133A	SEMA6B WIZ NFATC4 CASKIN2 PLPPR2 ARHGAP33	5.34e-04	196	117	6	265_DN
Drug	CP-319743 [172078-87-4]; Down 200; 10uM; PC3; HT_HG-U133A	GMIP RNF43 MEF2D MEGF8 TENM1 MAP3K9	5.34e-04	196	117	6	7491_DN
Drug	Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; MCF7; HT_HG-U133A	SEMA6B CC2D1A MYOF PHLDB1 WIZ PLPPR2	5.34e-04	196	117	6	6273_UP
Drug	haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A_EA	SETD1B PLXND1 PPP1R13L CBLB SPATA2L GPR153	5.34e-04	196	117	6	1041_UP
Drug	Piperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; PC3; HT_HG-U133A	IRS4 RNF43 RASIP1 SMPD1 DHX34 ARAP1	5.34e-04	196	117	6	3763_UP
Drug	Oxybenzone [131-57-7]; Down 200; 17.6uM; PC3; HT_HG-U133A	B4GALNT1 PLXND1 SPATA2L CASKIN2 SMPD1 DHX34	5.34e-04	196	117	6	6309_DN
Drug	Liothyronine [6893-02-3]; Down 200; 6.2uM; MCF7; HT_HG-U133A	IQSEC2 PHLDB1 WIZ SSH1 GPR153 DNM2	5.34e-04	196	117	6	3324_DN
Drug	Aceclofenac [89796-99-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A	IQSEC2 RFNG RGS3 SSH1 PHLPP1 SMPD1	5.34e-04	196	117	6	7029_DN
Drug	Meglumine [6284-40-8]; Down 200; 20.4uM; MCF7; HT_HG-U133A	DDX17 ADAM15 CC2D1A LRP6 DEDD ARAP1	5.34e-04	196	117	6	6445_DN
Drug	Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; MCF7; HT_HG-U133A	SETD1A LZTS3 RGS3 GPR153 SPON2 DHX34	5.34e-04	196	117	6	3441_UP
Drug	Trioxsalen [3902-71-4]; Up 200; 17.6uM; PC3; HT_HG-U133A	IQSEC2 MEF2D MEGF8 NFATC4 MYO15A DNASE1L2	5.34e-04	196	117	6	5736_UP
Drug	Pivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A	SETD1A RNF43 PHLPP1 TBX10 DHX34 PLPPR2	5.34e-04	196	117	6	6014_DN
Drug	AH6809; Up 200; 1uM; PC3; HT_HG-U133A	SETD1A PLXND1 MEF2D SPATA2L WIZ PLPPR2	5.49e-04	197	117	6	7049_UP
Drug	Hydrastine hydrochloride [5936-28-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A	SETD1B IQSEC2 CC2D1A PLXND1 AHDC1 PLPPR2	5.49e-04	197	117	6	6011_DN
Drug	Ethambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A	IRS4 PLXND1 TENM1 MMP17 DHX34 ARAP1	5.49e-04	197	117	6	4120_UP
Drug	Chloramphenicol [56-75-7]; Down 200; 12.4uM; PC3; HT_HG-U133A	ADAM15 CC2D1A AHDC1 RGS3 SPATA2L ARAP1	5.49e-04	197	117	6	1795_DN
Drug	Propylthiouracil [51-52-5]; Down 200; 23.4uM; MCF7; HT_HG-U133A	LZTS3 KDM6B SPATA2L CASKIN2 DHX34 PLPPR2	5.49e-04	197	117	6	2837_DN
Drug	(-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A	IRS4 RNF43 PHLDB1 CASKIN2 MMP17 ARAP1	5.49e-04	197	117	6	4134_UP
Drug	Lidoflazine [3416-26-0]; Up 200; 8.2uM; MCF7; HT_HG-U133A	SETD1A NFATC4 CASKIN2 MAP3K9 DHX34 ARHGAP33	5.49e-04	197	117	6	3201_UP
Drug	Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A	CC2D1A KDM6B CASKIN2 GPR153 LRP6 SMPD1	5.49e-04	197	117	6	3415_DN
Drug	Metrizamide [31112-62-6]; Up 200; 5uM; MCF7; HT_HG-U133A	SETD1B ADAM15 YRDC MYOF PHLDB1 DNASE1L2	5.49e-04	197	117	6	3255_UP
Drug	Spaglumic acid [4910-46-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	SETD1A KIAA0586 PLXND1 AHDC1 PHLDB1 CASKIN2	5.49e-04	197	117	6	7465_DN
Disease	neurodevelopmental disorder with speech impairment and dysmorphic facies (implicated_via_orthology)	SETD1A SETD1B	1.51e-05	2	115	2	DOID:0070417 (implicated_via_orthology)
Disease	gastric adenocarcinoma (is_implicated_in)	RNF43 KMT2D	8.09e-04	11	115	2	DOID:3717 (is_implicated_in)
Disease	stomach carcinoma (is_implicated_in)	CBLB RNF43	9.69e-04	12	115	2	DOID:5517 (is_implicated_in)
Disease	autism spectrum disorder (implicated_via_orthology)	MEF2B KMT5C MEF2D NLGN2	3.01e-03	152	115	4	DOID:0060041 (implicated_via_orthology)
Disease	pulse pressure measurement	THSD4 AMH RBM33 RGL3 KDM6B AHDC1 RCOR2 FASN MEGF8 PLXNC1 HHIPL1 DHX34 PALLD	3.04e-03	1392	115	13	EFO_0005763
Disease	intellectual disability (implicated_via_orthology)	MEF2B IRS4 MEF2D	3.18e-03	75	115	3	DOID:1059 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LPQARPPRPRSAPAF	AGBL5	831	Q8NDL9
SPPPPAPARAAAFLA	B3GALT6	46	Q96L58
APPQSPRRPELPDLA	B4GALNT1	41	Q00973
PRRPELPDLAPEPRY	B4GALNT1	46	Q00973
PPDFRLEPTAPALSP	AJUBA	106	Q96IF1
ELADRPNPPTRPLPA	ADAM15	786	Q13444
PSPPAPGAPVSRILF	SMPD1	191	P17405
DAPTFPRPPGPRNTL	ARHGEF15	381	O94989
VTPRALSDPEPRPPQ	DEDD	126	O75618
AFSENPRPPPRRDPS	AHDC1	56	Q5TGY3
RPPPAPASPRELLLD	DISP2	1206	A7MBM2
PFRRLAILPASAPPA	ITIH4	686	Q14624
VSRFVRPPPSAPEPA	RC3H1	621	Q5TC82
PPPLIRPALAAPRHS	RCOR2	486	Q8IZ40
VAPEPPLATRATAPP	RASIP1	131	Q5U651
APPPPQDRDPFFLGV	RBM33	451	Q96EV2
VFPRERPVRPALQPP	RBM33	521	Q96EV2
PPAAPRPAFVIPEVR	RGS3	846	P49796
RAPAPARTPAPAPRA	RFNG	31	Q9Y644
PPSRPAAPSLRPDDV	RFNG	46	Q9Y644
PLFSPPPVRRADLPF	NOBOX	441	O60393
LDPPPPPAAVEVFQR	ABI3	241	Q9P2A4
RSRPRAPAPVPQPFS	MBD6	386	Q96DN6
PQALFPARRRPPEFP	MAP3K10	861	Q02779
PRLPFRAPPATPLAS	HS3ST3B1	86	Q9Y662
FAPRPSELGPPDPRL	LZTS3	21	O60299
TPPSRPPPAEGFRLL	NUDT19	31	A8MXV4
PQCLDFRPPFRPTQP	HHIPL1	21	Q96JK4
LRRLAPAPPATPAPA	KMT5C	406	Q86Y97
VPPDLLAFPGPRPSF	MYO15A	731	Q9UKN7
LRTGPFQPPFLPPAR	MYO15A	801	Q9UKN7
FQPPFLPPARRPRSL	MYO15A	806	Q9UKN7
RGFSRPPPVPENPFL	MYO15A	951	Q9UKN7
QEFVRALRPEAPPPP	GMIP	346	Q9P107
RLPSTEPPPQGRPEF	IQSEC2	531	Q5JU85
RLFPEPLPPSSPGFR	EZHIP	166	Q86X51
YLARSIDPLPRPPSP	KDM6B	576	O15054
LEPAPPRARPEVAPE	LMTK3	1161	Q96Q04
ILREFAFPPPVSPRL	CBLB	966	Q13191
RPPRPAAPLPLLAYL	PLXNC1	11	O60486
VRFPPAAPPAEPVTV	PLXND1	161	Q9Y4D7
EPQALRRPPGPFPAA	GPR153	511	Q6NV75
EPPALPARPASAPQR	GXYLT2	31	A0PJZ3
KPAGLPPPAFRRSEP	MEGF8	2716	Q7Z7M0
PPPAFRRSEPFLAPL	MEGF8	2721	Q7Z7M0
SPPRPLPVPAAAAVA	LAPTM4B	11	Q86VI4
VVNRPRPHPPFVPSA	LRRC71	81	Q8N4P6
FPAILNPPPSPATER	LRP6	1481	O75581
LPSQRRSPPEEPPDF	IKBKG	381	Q9Y6K9
LDTVPFPPPRPSAEL	AMH	266	P03971
IAPRPARPPPVFADS	MROH6	686	A6NGR9
SPRPFALPLGSPRIP	RGL3	591	Q3MIN7
PPAAPSRPTIIRPAE	DNM2	851	P50570
IPAARLPSAPTPLRP	CASKIN2	351	Q8WXE0
GDPALPRPRLYPAAP	MEF2B	121	Q02080
LPAQSRPSPFRPAAP	MEF2B	161	Q02080
DPRALQSPPLRPPDV	MCIDAS	161	D6RGH6
APPRPTDRLAVPPFA	PMEPA1	111	Q969W9
TPAAPRPGFPAVPRE	PLIN1	476	O60240
CLPPSPDRPGPDRFV	PLPPR2	171	Q96GM1
RSPPLPPRVFLEELP	SLC34A1	606	Q06495
PPRVFLEELPPATPS	SLC34A1	611	Q06495
SPTPRQFGRAPVPPF	PALLD	766	Q8WX93
DRRFSCLPELPPPPE	ARHGAP33	116	O14559
PPFSPVPFVLPERSN	BPIFC	261	Q8NFQ6
PPPSDAPLPFDRVLV	C1QTNF5	116	Q9BXJ0
LPSRRALTPPPLPAA	DNASE1L2	146	Q92874
PLSPRALRPPPVALA	FAM83C	316	Q9BQN1
ALRPPPVALAFRPDV	FAM83C	321	Q9BQN1
TPSQFPPLRPRFDPV	FBXO7	471	Q9Y3I1
DTRRPVPPLTPRPYF	B3GAT2	26	Q9NPZ5
PTQPAPRIASAPEPR	CC2D1A	211	Q6P1N0
DRIPQFFIPPRLPDP	C2CD4D	46	B7Z1M9
AVVARTPPEPRPSPE	MAP7D1	16	Q3KQU3
DRPRPPLPESLSTFP	ITIH6	891	Q6UXX5
LPLPPPPFARAEDAA	EFNA2	16	O43921
SIDERPPVSRAPPQP	EML5	1331	Q05BV3
PPRPPRPLHLSDRSF	FAM102A	291	Q5T9C2
RPEPQALPSPAIRAP	DDX17	56	Q92841
FRFLPPEDTPPPAQG	NOS1AP	431	O75052
YFTVPRPDPVRPIDP	DVL1P1	346	P54792
FPPVEFPAPRGTPLI	FASN	816	P49327
RTFPFIEPPPPASLE	DHX34	541	Q14147
PPAPVAAAAPARAPR	SAMD1	136	Q6SPF0
LKRPRPPFARGPPFF	RPRD2	1436	Q5VT52
FFPERGPSPRPPATA	PPP1R13L	196	Q8WUF5
TPPLGARRFQPPEAP	NLGN2	76	Q8NFZ4
PPAPLRRPLAVLHAP	KIFC2	786	Q96AC6
GEFPRLPDPNVVFPP	MAP3K9	956	P80192
SRERSPAPPPPAVFP	MEF2D	446	Q14814
PNRPSKVFPALRSPP	MICAL2	1611	O94851
APRDVPPLQAARPAP	INAFM2	106	P0DMQ5
LAPSPARPRHPAEAP	IRS4	436	O14654
LPSAASERRPPPPDF	MN1	721	Q10571
FPPLEFRPVPLPSGE	POLR3GL	41	Q9BT43
PLPPRGSPAAYRAPL	SPATA2L	211	Q8IUW3
QSPRAFIPPAPVLPS	SPON2	246	Q9BUD6
ALPPAPAAPRPALRA	TOR2A	216	Q8N2E6
AVRPEPPAPAPAALE	TGFBR3L	251	H3BV60
QPPAVSFLPRPFPSD	NFATC4	776	Q14934
LLPEPPDNRSSAPPR	MMP17	311	Q9ULZ9
PAPPPPRADRFAFRL	PPP1R3E	211	Q9H7J1
FRLTPPSPVRSEPQP	PPP1R35	81	Q8TAP8
VARPPRPGPFLPSQE	RNF43	366	Q68DV7
FPALEPSPRQPPARA	SHISA8	281	B8ZZ34
PPRPLPRSTFSRPAF	TENM1	291	Q9UKZ4
RAQARAPTPLPPLLP	SETD1B	1491	Q9UPS6
DLPAQPPPLAPFRRV	WIZ	156	O95785
PPPLAPFRRVFVPVE	WIZ	161	O95785
RPPEPVPAPAALFSS	SETD1A	1316	O15047
PPPFLPPAGSRRADT	SSH1	711	Q8WYL5
APRPTPGPRAFQLPD	B3GNT9	46	Q6UX72
PEERFRAPPILPPHL	PRKAB1	196	Q9Y478
RHIFRSPPVPATPPE	ARAP1	86	Q96P48
PLAARPAPAPAAPRP	CLEC2L	16	P0C7M8
PPPEVLLAPATYRPV	TBX10	311	O75333
PERVRVSLSAPPPPY	TMEM92	106	Q6UXU6
LFPEEPPPLSVAPRD	SEMA6B	26	Q9H3T3
PQPKAAPRTFLRPSP	TJP2	486	Q9UDY2
AKSPRQPPAPRRDPF	SIDT1	26	Q9NXL6
FARVSDSIPPLPPPQ	WASH4P	451	A8MWX3
FARVSDSIPPLPPPQ	WASH3P	436	C4AMC7
PFAPAPRPRRAAVPA	TMDD1	176	P0DPE3
AEEPLRPFLAPSVPP	RFPL2	336	O75678
EEPLRPFLAPSIPPN	RFPL3	276	O75679
GTLQDRPPSPFREPP	PHLDB1	396	Q86UU1
SPLAPRYVVEPPRLP	ZDHHC8	246	Q9ULC8
DPPRPLPRSFSPVLG	ZDHHC8	516	Q9ULC8
LAPPEPRDSEVPPAR	PHLPP1	271	O60346
RFSPHRPDNLVPPAP	THSD4	596	Q6ZMP0
SPLETPAPRRFAPVP	KIAA0586	321	Q9BVV6
RLFRPPSPAPAAPGA	YRDC	31	Q86U90
FPSDDRLSRPPPPAT	KMT2D	2766	O14686
PAPPRQFRELPDSVP	MYOF	1536	Q9NZM1