Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal retina bipolar cell morphology

CACNA1F RELN SYNE2 AMIGO1

3.00e-0537684MP:0006073
MousePhenoabnormal cerebellar Purkinje cell layer

RELN GLB1 SUMF1 SPG11 ELP2 CIT LYST

9.33e-05220687MP:0000875
MousePhenoabnormal cerebellar cortex morphology

RELN GLB1 SUMF1 LRP2 SPG11 ELP2 CIT LYST

9.91e-05300688MP:0004097
MousePhenoabnormal retina horizontal cell morphology

CACNA1F SYNE2 AMIGO1

1.01e-0419683MP:0006068
MousePhenoabnormal mean corpuscular volume

KIF20A FMO1 CES1 TEX2 SYNE2 GKN2 MED25 BBS5 TSPAN32 LYST

1.14e-044876810MP:0000226
DomainChitinase_insertion

CHI3L1 CHI3L2

1.75e-045792IPR029070
Domain-

CHI3L1 CHI3L2

1.75e-0457923.10.50.10
DomainGlyco_hydro_18_chit_AS

CHI3L1 CHI3L2

2.62e-046792IPR001579
DomainPH_BEACH

LRBA LYST

2.62e-046792PF14844
DomainGlyco_hydro18_cat

CHI3L1 CHI3L2

3.66e-047792IPR001223
DomainGlyco_hydro_18

CHI3L1 CHI3L2

3.66e-047792PF00704
DomainChitinase_II

CHI3L1 CHI3L2

3.66e-047792IPR011583
DomainGlyco_18

CHI3L1 CHI3L2

3.66e-047792SM00636
DomainCHITINASE_18

CHI3L1 CHI3L2

3.66e-047792PS01095
Domain-

GLB1 CHI3L1 CHI3L2

4.32e-04357933.20.20.80
DomainPH-BEACH_dom

LRBA LYST

4.87e-048792IPR023362
Domain-

LRBA LYST

4.87e-0487922.30.29.40
DomainPH_BEACH

LRBA LYST

4.87e-048792PS51783
DomainGlyco_hydro_catalytic_dom

GLB1 CHI3L1 CHI3L2

5.52e-0438793IPR013781
DomainBEACH_dom

LRBA LYST

6.24e-049792IPR000409
DomainBEACH

LRBA LYST

6.24e-049792PS50197
DomainBeach

LRBA LYST

6.24e-049792PF02138
Domain-

LRBA LYST

6.24e-0497921.10.1540.10
DomainBeach

LRBA LYST

6.24e-049792SM01026
DomainSialidases

RELN SORCS3

6.24e-049792IPR011040
DomainGlycoside_hydrolase_SF

GLB1 CHI3L1 CHI3L2

1.47e-0353793IPR017853
DomainLdl_recept_b

LRP1 LRP2

1.56e-0314792PF00058
DomainLDLRB

LRP1 LRP2

1.56e-0314792PS51120
DomainLY

LRP1 LRP2

1.79e-0315792SM00135
DomainLDLR_classB_rpt

LRP1 LRP2

1.79e-0315792IPR000033
Domain-

IFT140 RPTOR PLXNA4 ELP2 LRBA LYST

2.86e-033337962.130.10.10
DomainWD40/YVTN_repeat-like_dom

IFT140 RPTOR PLXNA4 ELP2 LRBA LYST

2.95e-03335796IPR015943
DomainWD40

IFT140 RPTOR ELP2 LRBA LYST

4.83e-03259795PF00400
DomaincEGF

LRP1 LRP2

5.38e-0326792IPR026823
DomaincEGF

LRP1 LRP2

5.38e-0326792PF12662
DomainWD40

IFT140 RPTOR ELP2 LRBA LYST

5.57e-03268795SM00320
DomainIPT

PLXNA4 PKHD1

5.79e-0327792SM00429
DomainWD40_repeat

IFT140 RPTOR ELP2 LRBA LYST

5.92e-03272795IPR001680
DomainWD_REPEATS_1

IFT140 RPTOR ELP2 LRBA LYST

6.49e-03278795PS00678
DomainWD_REPEATS_2

IFT140 RPTOR ELP2 LRBA LYST

6.58e-03279795PS50082
DomainWD_REPEATS_REGION

IFT140 RPTOR ELP2 LRBA LYST

6.58e-03279795PS50294
DomainTIG

PLXNA4 PKHD1

7.59e-0331792PF01833
DomainIPT

PLXNA4 PKHD1

8.07e-0332792IPR002909
Pubmed

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.

CACNA1F ALMS1 UCHL3 SYNE2 LRP2 BBS5 MYRF

1.90e-0623386732290105
Pubmed

Human colostrum: identification of minor proteins in the aqueous phase by proteomics.

MFGE8 SMPDL3B AHSG CHI3L1 CHI3L2 ACE

3.22e-0616286616502470
Pubmed

Enhanced expression of the human chitinase 3-like 2 gene (YKL-39) but not chitinase 3-like 1 gene (YKL-40) in osteoarthritic cartilage.

CHI3L1 CHI3L2

6.04e-06286212435396
Pubmed

Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice.

A1CF RPTOR

6.04e-06286221357822
Pubmed

Chitinase 3-like proteins as diagnostic and prognostic biomarkers of multiple sclerosis.

CHI3L1 CHI3L2

6.04e-06286225698171
Pubmed

Chitinase expression in Alzheimer's disease and non-demented brains regions.

CHI3L1 CHI3L2

6.04e-06286227653898
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

6.04e-06286234445520
Pubmed

CHI3L1 and CHI3L2 overexpression in motor cortex and spinal cord of sALS patients.

CHI3L1 CHI3L2

6.04e-06286228989002
Pubmed

Two closely related human members of chitinase-like family, CHI3L1 and CHI3L2, activate ERK1/2 in 293 and U373 cells but have the different influence on cell proliferation.

CHI3L1 CHI3L2

6.04e-06286222211103
Pubmed

Role of chitinase-like proteins in cancer.

CHI3L1 CHI3L2

1.81e-05386226733160
Pubmed

Genetics of migraine in the age of genome-wide association studies.

LRP1 TRPM8

1.81e-05386222072275
Pubmed

Deciphering the Role of the rs2651899, rs10166942, and rs11172113 Polymorphisms in Migraine: A Meta-Analysis.

LRP1 TRPM8

1.81e-05386235454329
Pubmed

Genetic architecture of human thinness compared to severe obesity.

PKHD1 PRDM6

1.81e-05386230677029
Pubmed

Genome-wide association study reveals three susceptibility loci for common migraine in the general population.

LRP1 TRPM8

1.81e-05386221666692
Pubmed

Association of PS1 1/2, ACE I/D, and LRP C/T polymorphisms with Alzheimer's disease in the Chinese population: a meta-analysis of case-control studies.

LRP1 ACE

1.81e-05386225730041
Pubmed

Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.

PPP1R3C PKHD1 LRP2

1.88e-052186327591083
Pubmed

Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.

LRP1 LRP2

3.61e-05486212413896
Pubmed

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.

LRP1 LRP2

3.61e-0548627775583
Pubmed

Circular RNA circ-CHI3L1.2 modulates cisplatin resistance of osteosarcoma cells via the miR-340-5p/LPAATβ axis.

CHI3L1 CHI3L2

3.61e-05486234164774
Pubmed

Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.

LRP1 LRP2

3.61e-05486211421580
Pubmed

The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal.

KIF20A SYNE2

3.61e-05486233686165
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

TEX2 RPTOR SYNE2 LRP2 SPG11 LRBA LYST FAM83B

3.63e-0550486834432599
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

MFGE8 ZNHIT6 SMPDL3B GLB1 MYO1D PKHD1 LRP2 AHSG NOX3 ACE FIGNL1

4.15e-051016861119056867
Pubmed

New paralogues and revised time line in the expansion of the vertebrate GH18 family.

CHI3L1 CHI3L2

6.01e-05586223558346
Pubmed

MFGE8 links absorption of dietary fatty acids with catabolism of enterocyte lipid stores through HNF4γ-dependent transcription of CES enzymes.

MFGE8 CES1

6.01e-05586236924494
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP1 LRP2

6.01e-05586219047013
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

LRP1 LRP2

6.01e-05586218685438
Pubmed

ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.

LRP1 LRP2

6.01e-05586216101684
Pubmed

The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.

PKHD1 LRP2

6.01e-05586220048263
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

ALMS1 MYO1D TEX2 RPTOR SYNE2 LRP2 SRP72 TRAK2 FIGNL1 TOP3B NUP160 ELAC2 FAM83B

7.65e-051496861332877691
Pubmed

Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence.

RPTOR MYRF

9.01e-05686234260928
Pubmed

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.

LRP1 LRP2

9.01e-0568629837937
Pubmed

KIF14 and citron kinase act together to promote efficient cytokinesis.

KIF20A CIT

9.01e-05686216431929
Pubmed

mTORC1 impedes osteoclast differentiation via calcineurin and NFATc1.

RELN RPTOR

9.01e-05686230271915
Pubmed

ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors.

A1CF LRP1

9.01e-05686227400128
Pubmed

Arf4 is required for Mammalian development but dispensable for ciliary assembly.

PKHD1 LRP2

1.26e-04786224586199
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

LRP1 LRP2

1.26e-04786212169628
Pubmed

ACE variants and risk of intracerebral hemorrhage recurrence in amyloid angiopathy.

LRP1 ACE

1.68e-04886220381197
Pubmed

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.

RELN LRP1

1.68e-04886210380922
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

CACNA1F LRP2 AHSG LRBA CDC27 F2RL2

1.70e-0432986617474147
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

MYO1D MARS1 RPTOR PKHD1 LRP2

1.71e-0420886533230847
Pubmed

An introduction of genetics in otosclerosis: a systematic review.

RELN ACE

2.15e-04986224170657
Pubmed

A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity.

CD3E TSPAN32

2.15e-04986220709950
Pubmed

LDL receptor-related protein as a component of the midkine receptor.

LRP1 LRP2

2.15e-04986210772929
Pubmed

Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway.

MARS1 RPTOR

2.68e-041086222424946
Pubmed

Genome-wide association analysis identifies susceptibility loci for migraine without aura.

LRP1 TRPM8

2.68e-041086222683712
Pubmed

Integral and associated lysosomal membrane proteins.

RPTOR LRP1 LRP2 SPG11

2.77e-0412686417897319
Pubmed

A forward genetic screen in mice identifies mutants with abnormal cortical patterning.

RELN LRP2

3.28e-041186223968836
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP2

3.28e-041186224639464
Pubmed

Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development.

LRP2 ACE

3.28e-041186222999937
Pubmed

An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3.

LRP1 ACE

3.28e-041186219105203
Pubmed

Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling.

KIF20A CDC27

3.93e-041286226986935
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LPIN3 RPTOR SUMF1 LRBA CIT MYRF LYST TOP3B ELAC2 PPP1R16A

4.01e-041105861035748872
Pubmed

SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

RELN SYNE2

5.39e-041486219874786
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP1 LRP2

5.39e-041486215082773
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP1 LRP2

5.39e-041486217389516
Pubmed

New loci associated with kidney function and chronic kidney disease.

ALMS1 UBE2Q2 AMIGO1

5.97e-046686320383146
Pubmed

Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease.

LRP1 ACE

6.21e-041586211436125
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

RELN PLXNA4

8.02e-041786211683995
Pubmed

Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia.

MFGE8 LRP1

8.02e-041786230647151
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYO1D CES1 SYNE2 PLXNA4 PKHD1 SRP72 SPG11 CDC27 LYST TOP3B FER1L6

8.46e-041442861135575683
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

LRP1 LRP2

9.01e-041886210827173
Pubmed

Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

CES1 AHSG ACE

9.36e-047786316944957
Pubmed

Genetic mapping of 20 novel expressed sequence tags from midgestation mouse embryos suggests chromosomal clustering.

MED25 LYST

1.01e-03198629070936
Pubmed

Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.

PRMT6 TRPM8

1.01e-031986224165912
Pubmed

Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population.

CES1 UCHL3

1.01e-031986212721789
Pubmed

Vhl safeguards thymic epithelial cell identity and thymopoietic capacity by constraining Hif1a activity during development.

PPP1R3C CD3E

1.12e-032086239040069
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP1 LRP2

1.23e-032186221337463
Pubmed

An atlas of genetic influences on human blood metabolites.

ALMS1 ACE MYRF HAO2

1.29e-0319086424816252
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

LPIN3 ALMS1 TEX2 RPTOR SYNE2 RASSF8 LYST FAM83B

1.32e-0386186836931259
Pubmed

Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip.

CACNA1F ALMS1 BBS5

1.33e-038786320801516
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

KIF20A ALMS1 MARS1 RPTOR SRP72 NUP160

1.44e-0349486626831064
Pubmed

Charcot-Marie-Tooth Neuropathy Type 2 – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

MARS1 MED25

1.48e-032386220301462
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

MARS1 TBC1D2B SPG11 LRBA HAO2 TOP3B

1.48e-0349786636774506
Pubmed

Leber Congenital Amaurosis / Early-Onset Severe Retinal Dystrophy Overview

IFT140 ALMS1

1.75e-032586230285347
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

KIF20A IFT140 ZNHIT6 ALMS1 RPTOR LRP1 LRP2 LRRC8B CDC27

1.76e-03111686931753913
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

ALMS1 TEX2 TRAK2 RASSF8

1.83e-0320986436779422
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

KIF20A CDC27 CIT NUP160

1.86e-0321086416565220
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

IFT140 LRP1 LRP2

1.99e-0310086325807483
Pubmed

Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.

GLB1 LRP2

2.04e-032786228167773
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SYNE2 CIT MYRF

2.10e-0310286310231032
Pubmed

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.

ELP2 LRBA CDC27

2.34e-0310686331024071
Pubmed

TopBP1 controls BLM protein level to maintain genome stability.

CDC27 TOP3B

2.35e-032986224239288
Cytoband1p13.3

PRMT6 CHI3L2 AMIGO1

3.04e-04698631p13.3
GeneFamilyChitinases

CHI3L1 CHI3L2

2.18e-047592816
GeneFamilyWD repeat domain containing|BEACH domain containing

LRBA LYST

3.71e-0495921230
GeneFamilyLow density lipoprotein receptors

LRP1 LRP2

7.98e-0413592634
GeneFamilyWD repeat domain containing

IFT140 RPTOR ELP2 LRBA LYST

1.63e-03262595362
CoexpressionICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_DN

PPP1R3C RELN CES1 HAO2 ELAC2

1.13e-0656865M13337
CoexpressionICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_DN

PPP1R3C RELN CES1 HAO2 ELAC2

2.21e-0664865MM1257
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6 IGDCC4

1.86e-0619086645df8fee00f8949937863159d7aa042e72748d9b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6 IGDCC4

1.92e-06191866b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6 IGDCC4

1.98e-06192866f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6 IGDCC4

1.98e-06192866dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6 IGDCC4

2.10e-0619486660622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6 IGDCC4

2.10e-0619486689b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T|COVID-19_Mild / Disease, condition lineage and cell class

CD3E RPTOR SYNE2 LRBA CHI3L2 LYST

2.43e-06199866f307d4887b28cf60a591439e278fd668409cb104
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|368C / Donor, Lineage, Cell class and subclass (all cells)

TRAV8-2 CD3E BBS5 TSPAN32 MYRF

1.08e-05150865c843bcf98c5fad2ca4339602f721f3fb782ae353
ToppCellPBMC-Control-cDC_2|Control / Compartment, Disease Groups and Clusters

AMHR2 CD3E SYNE2 PRDM6 FAM83B

1.19e-051538654ee37266b0054f276c7a73ab9220f681b9d74c71
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B LRP1 SORCS3 SPG11 ACE

1.87e-05168865f45dbcd7753117a3e41e1412bce2100d52fa7fd0
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNA4 PKHD1 LRP2 SORCS3 TRPM8

1.92e-0516986512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelldroplet-Kidney-nan-3m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMHR2 FMO1 LRP2 ACE HAO2

1.97e-05170865dd48fd3c5c67eb71183981f42975a538f12077c3
ToppCellInt-URO-Lymphocyte-T_NK-MAIT|Int-URO / Disease, Lineage and Cell Type

B3GALT2 CD3E SYNE2 LRBA F2RL2

2.21e-051748655227ed29f5f0d3e0aaa7f3cfd362f96d3e2660f7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FMO1 A1CF SYNE2 LRP2 HAO2

2.33e-051768651595dbeee336a81e581325d63208ec6262664ee9
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FMO1 A1CF PKHD1 LRP2 HAO2

2.46e-0517886523a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 PRDM6 IGDCC4

2.60e-0518086508ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2|TCGA-Skin / Sample_Type by Project: Shred V9

MYO1D TEX2 TRAK2 LRBA LYST

2.67e-051818659d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

FMO1 A1CF PKHD1 LRP2 HAO2

2.67e-051818656980ea624151da32b7f537f263e40fcb87a02e81
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

FMO1 A1CF SYNE2 PKHD1 LRP2

2.81e-051838656878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell10x3'2.3-week_12-13-Lymphocytic_T-T_NK-CD8_T_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

B3GALT2 MFGE8 CD3E CHI3L2 AMIGO1

2.81e-05183865bbe389d5bee8754210f5ec4039a5ecba6a3977a9
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RELN A1CF PKHD1 LRP1 TSPAN32

2.96e-051858651d874608aa2062024323512f68889219471b2f00
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma|TCGA-Kidney / Sample_Type by Project: Shred V9

IFT140 SPEF1 SMPDL3B ARHGAP40 ELAC2

2.96e-0518586546f4f6f20b1e152922f6f2ba1244c56e48a49b79
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO1D SYNE2 PKHD1 TSPEAR MYRF

3.12e-0518786558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D PKHD1 SORCS3 LYST FAM83B

3.12e-0518786577886f99c229610abd28c4c370d2c7d1536c9782
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

A1CF SUMF1 PKHD1 LRBA LYST

3.12e-05187865f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6

3.28e-05189865a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6

3.28e-05189865e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6

3.36e-05190865841cd55861b43578d704418b9bc0af2e8b88323a
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6

3.36e-05190865d60395739458d7f47a3350ade751fe3819500320
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

AMHR2 FMO1 SMPDL3B LRP2 MYRF

3.45e-051918654c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCellCOVID-19-kidney-Mito-rich_Distal|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNE2 PKHD1 SORCS3 CIT FAM83B

3.45e-051918650965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6

3.54e-051928656f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 IGDCC4

3.54e-05192865df1545670370fb1010c567cd059c2783eab315f7
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6

3.54e-05192865162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6

3.54e-051928653d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6

3.54e-051928654e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6

3.54e-05192865ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 PRDM6 IGDCC4

3.54e-05192865deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA4 LRP1 SORCS3 CHI3L1 PRDM6

3.71e-051948656e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AMHR2 A1CF SMPDL3B TSPEAR TRPM8

3.90e-0519686595544097577f20ed7f4144bd940471cde0617554
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FMO1 A1CF LRP2 HAO2 PPP1R16A

3.90e-051968654ebcaac758ed01d918de9c1cd383a84457b615f3
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SMPDL3B GKN2 LRP2 CHI3L1 CHI3L2

4.00e-05197865d2a4d7e92e91bcc47a7657da2e5c8a3ad7eb08ad
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FMO1 A1CF LRP2 HAO2 PPP1R16A

4.09e-0519886572733b6149b797ac11cc108bc80428b77fbbba78
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FMO1 A1CF LRP2 HAO2 PPP1R16A

4.09e-05198865f23559ce6072e3c323f6791ff95269271b0f7ff1
ToppCell(7)_Epithelial_cells-(7)_Epithelial-B_(AT2)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

GLB1 GKN2 LRP2 CHI3L1 CHI3L2

4.09e-05198865391f59e232269f6ae9f8792d21a60ad534e03c4d
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FMO1 A1CF LRP2 HAO2 PPP1R16A

4.19e-051998654bde35e5df019189433d65d415e29a0c1145ac66
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CACNA1F MYO1D SYNE2 PKHD1 MYRF

4.19e-05199865d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PLXNA4 LRP1 SORCS3 CHI3L1 IGDCC4

4.19e-051998658b86c69aaf60feff53aa782559cfece7342a23de
ToppCellControl-Control-Lymphocyte-T/NK-dn_T|Control / Disease, condition lineage and cell class

CACNA1F CD3E SYNE2 CHI3L2 LYST

4.29e-0520086510882c59b7aaf8bd4b5c00aa4ddbb9f7ac5b2cf5
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CACNA1F MYO1D SYNE2 PKHD1 MYRF

4.29e-052008658683445ad5b70748c4a1f12eb77d47623085147e
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MFGE8 FMO1 IZUMO4 LRP1 ELP2

4.29e-052008655ad3ea1cf1fcd4100966c5517bc7ed0a1af54317
ToppCellBiopsy_IPF-Epithelial-KRT5-/KRT17+|Biopsy_IPF / Sample group, Lineage and Cell type

MFGE8 SMPDL3B SYT12 PKHD1 MYRF

4.29e-052008652fc7a3b3aea711ad3d96fd9513f4b40533056d86
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-MAIT|Int-URO / Disease, condition lineage and cell class

B3GALT2 CD3E SYNE2 LRBA F2RL2

4.29e-05200865043c18e79a969e37bbff86443e553ac09fe33f84
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AHSG FIGNL1 TOP3B ELAC2

1.79e-04145864186b8bd8ac2d5c66cc29fdc2dd6751eddce3e8b8
ToppCellIIH-CD4-antiviral_CD4|IIH / Condition, Cell_class and T cell subcluster

IFT140 SYT12 PPIL6 PARP9

1.94e-04148864ec626a44cea83f2a0e5c27fc8182f96446d297ac
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

UCHL3 TSPEAR SORCS3 CIT

1.99e-0414986410ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCellCerebellum-Macroglia-ASTROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

PPP1R3C SMPDL3B CHI3L1 IGDCC4

2.09e-0415186471841d2001200d1595c85c2b007ee20791a72927
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1|Cerebellum / BrainAtlas - Mouse McCarroll V32

PPP1R3C SMPDL3B CHI3L1 IGDCC4

2.09e-0415186460aced0c1cc6b509b73308d03d58a3c44d712ef4
ToppCellsevere_influenza-NK_CD56bright|World / disease group, cell group and cell class (v2)

SYT12 PPIL6 CCDC168 AMIGO1

2.25e-04154864187b9d4eb0e98c506034735601ead480ff00bd57
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

UCHL3 TSPEAR SORCS3 CIT

2.31e-0415586499e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRP1 CHI3L1 CHI3L2 IGDCC4

2.37e-04156864bb505f639dbcad2b788db62d6084c2cb4e884bec
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|367C / Donor, Lineage, Cell class and subclass (all cells)

CD3E SYNE2 CHI3L2 TSPAN32

2.37e-0415686471f49db7d6da5533ecfcd4eacb50ecf1f30ee712
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B TBC1D2B LRP1 HAO2

2.49e-04158864b0508a600994090c6aafd8d779437190a33ad821
ToppCellfacs-Lung-EPCAM-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B TBC1D2B LRP1 HAO2

2.49e-04158864a816cc095452308d06f87b77467e2a8c6361fd2a
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF20A ALMS1 F2RL2 FIGNL1

2.49e-04158864ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

B3GALT2 CD3E LRBA FIGNL1

2.61e-041608648e2b51d7b42e0b6e62641efdbbc73d31561d6a3e
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLHL30 TBC1D2B MED25 LRBA

2.61e-041608648374ae912337947b2cc8d17d5840f306361fe1ff
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TRAV8-2 CD3E RPTOR LYST

2.73e-04162864a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCellfacs-Kidney-nan-3m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E ALMS1 KLHL30 TSPAN32

2.80e-04163864385b24e18df5ef92108483de312d6c85a1e6d145
ToppCellfacs-Kidney-nan-3m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD3E ALMS1 KLHL30 TSPAN32

2.80e-041638648004cc0b3428be08b89957b563cd8799f822d931
ToppCellURO-Lymphocyte-T_NK-MAIT|URO / Disease, Lineage and Cell Type

B3GALT2 CD3E SYNE2 MYRF

2.86e-04164864cb42a70433b3968caca67f7aa98ea536cd90a0bc
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRMT6 A1CF CIT FIGNL1

2.86e-041648644ef776d1bab4103d42d3a4f22cdfb49e8d2bc5a0
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells-CLP|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD3E TRPM8 CHI3L2 TSPAN32

2.86e-04164864f5cacd7b2329cb0c7c1696eb4d8f89a4bbd9dda1
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-7|TCGA-Kidney / Sample_Type by Project: Shred V9

IFT140 RELN SPEF1 ARHGAP40

3.00e-04166864b545de32578047c9ca422354b8992f2d9c9e1cc7
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK-NK_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TRAV8-2 CD3E CHI3L2 FER1L6

3.00e-0416686405d3e7f441089d788a192d7fa1ec5c302d1ca202
ToppCellP15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

AMHR2 IZUMO4 ARHGAP40 TEX2

3.07e-041678645c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCellmild_COVID-19-Treg|World / disease group, cell group and cell class (v2)

TRAV8-2 CD3E SYNE2 TRPM8

3.07e-0416786469330689b6e353c8ee9ea1b63a5eac6ab38d456f
ToppCellnormal_Lung-Fibroblasts-Mesothelial_cells|Fibroblasts / Location, Cell class and cell subclass

AMHR2 A1CF LRP2 FAM83B

3.07e-04167864892a2dc83ab5de5a1016402f8e95d2aabf651326
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FMO1 A1CF LRP2 HAO2

3.14e-04168864fa0d251693935116adf633d02b7ec4a295100865
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNE2 PKHD1 LRP2 MYRF

3.14e-04168864a086c306be430adf0632ba53e98cd8014d2de330
ToppCell356C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

IFT140 SYT12 FIGNL1 AMIGO1

3.21e-041698640425d2580ed325178f522c0093ff4623de6ce7a8
ToppCell356C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

IFT140 SYT12 FIGNL1 AMIGO1

3.21e-04169864fec669968a77060bd77ee8695034e35a642c984f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGAP40 MYO1D SYNE2 CIT

3.28e-04170864a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCellIonocyte|World / Class top

AMHR2 PLXNA4 ACE MYRF

3.28e-04170864d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPTOR RASSF8 PRDM6 IGDCC4

3.28e-04170864b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B AHSG CHI3L1 ACE

3.36e-04171864355a27ea88410a84210f7e4298c7c4f90cf2f8a9
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA1F AMHR2 PLXNA4 TSPAN32

3.36e-041718645885e69e997cc2f6a27afebfe57001ca0ac062a6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP40 PKHD1 SORCS3 IGDCC4

3.43e-041728640c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP40 PKHD1 SORCS3 IGDCC4

3.43e-04172864eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AMHR2 SMPDL3B LRP2 MYRF

3.51e-041738643d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AMHR2 SMPDL3B LRP2 MYRF

3.51e-041738643aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF20A FMO1 SYNE2 TRAK2

3.58e-041748649d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF20A FMO1 SYNE2 TRAK2

3.58e-0417486453cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-CD4_TEM|Multiple_Sclerosis / Disease, Lineage and Cell Type

B3GALT2 CD3E SYNE2 AHSG

3.58e-04174864d2ea5b55bf03a8013816d073896208f311c3e544
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R3C MFGE8 SYT12 PRDM6

3.66e-04175864b80fe906043b3cb0b3ba761aadc9dc1c364aa1bf
ToppCell10x5'-Lung-Lymphocytic_Invariant-Inducer-like-MAIT|Lung / Manually curated celltypes from each tissue

CD3E MYO1D SYNE2 GKN2

3.66e-04175864f6663e5a9c87e27f3459a6481768b03aff7d0855
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

B3GALT2 CD3E SYNE2 TRPM8

3.66e-04175864cc2428150987911d0d382e8177918724aa69f85c
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B SYNE2 LRP1 ACE

3.66e-04175864cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMA16 GKN2 CHI3L2 UBE2Q2

3.66e-04175864dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R3C MFGE8 SYT12 PRDM6

3.66e-04175864067c7d89cfdf6ebf70692df64b9b79d752f093dd
DiseaseMoyamoya disease

SMPDL3B RPTOR LRP1 MYRF

4.92e-0640834MONDO_0016820
DiseaseCommon Migraine

LRP1 TRPM8

1.63e-047832C0338480
DiseaseAcute Confusional Migraine

LRP1 TRPM8

2.78e-049832C0521664
DiseaseStatus Migrainosus

LRP1 TRPM8

2.78e-049832C0338489
DiseaseAbdominal Migraine

LRP1 TRPM8

2.78e-049832C0270858
DiseaseSick Headaches

LRP1 TRPM8

2.78e-049832C0700438
DiseaseCervical Migraine Syndrome

LRP1 TRPM8

2.78e-049832C0007852
DiseaseHemicrania migraine

LRP1 TRPM8

2.78e-049832C0018984
Diseaseserum metabolite measurement

ALMS1 GLT1D1 SYNE2 SORCS3 TRPM8 ELP2 ACE CIT MYRF HAO2

3.18e-049458310EFO_0005653
Diseasecreatinine measurement, glomerular filtration rate

A1CF ALMS1 LRP2 UBE2Q2

3.39e-04117834EFO_0004518, EFO_0005208
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

PKHD1 ACE

4.23e-0411832DOID:0110861 (biomarker_via_orthology)
DiseaseHypoxanthine measurement

PKHD1 AMIGO1

5.98e-0413832EFO_0021604
DiseaseMigraine Disorders

LRP1 TRPM8

5.98e-0413832C0149931
DiseaseAnilide use measurement

LRP1 TRPM8

8.02e-0415832EFO_0009938
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

PKHD1 ACE

9.14e-0416832DOID:0110861 (implicated_via_orthology)
Diseasemigraine without aura, susceptibility to, 4

LRP1 TRPM8

9.14e-0416832MONDO_0011847
Diseasecystatin C measurement

PRMT6 ALMS1 PKHD1 LRP1 LRP2 UBE2Q2

9.62e-04402836EFO_0004617
Diseasemetabolite measurement

FMO1 ALMS1 CES1 SYNE2 ACE MYRF HAO2

1.02e-03560837EFO_0004725
Diseaseblood metabolite measurement

ALMS1 PPP1R16A

1.30e-0319832EFO_0005664
DiseaseCOVID-19, mortality

SUMF1 LRP2 ELP2 BBS5

1.37e-03170834EFO_0004352, MONDO_0100096
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

CES1 SYNE2 AHSG SPG11 MYRF

1.40e-03291835EFO_0008317, EFO_0020946
DiseaseAntimigraine preparation use measurement

LRP1 TRPM8

1.59e-0321832EFO_0009939
Diseasenephrosis (biomarker_via_orthology)

LRP2 ACE

1.74e-0322832DOID:2527 (biomarker_via_orthology)
Diseasecoronary artery disease

IFT140 CD3E RPTOR PKHD1 SHOC1 LRP1 NOX3 NUP160 PRDM6 FAM83B

1.89e-0311948310EFO_0001645
Diseasepain

CD3E LRP1 SORCS3 TRPM8

2.30e-03196834EFO_0003843

Protein segments in the cluster

PeptideGeneStartEntry
HWPEYNQKEGYLQIG

CES1

516

P23141
PQEHVYDKINGVWNL

BBS5

156

Q8N3I7
WIKNGLYLHNNPLNC

AMIGO1

211

Q86WK6
QKNNWGQPVYQLHSA

A1CF

456

Q9NQ94
ENELHGEKLGWPQYN

ACE

1211

P12821
PLTCHVWQQIVYQGN

ALMS1

111

Q8TCU4
NNDSEIWGLLQPYQH

BTBD11

356

A6QL63
DQQVPYAVKGNQWVG

CHI3L2

321

Q15782
WIPQLQYAFQDKNHL

CIT

156

O14578
HEERWQNGQYKPGIA

AMHR2

316

Q16671
NLLIANAQPWHSGVY

IGDCC4

296

Q8TDY8
HENPIISLNKWGQYA

RASSF8

56

Q8NHQ8
LGENYSWQIPINHND

PARP9

56

Q8IXQ6
YDPGANLWQKVQSQH

KLHL30

486

Q0D2K2
HGQPVWLTQIQEYAN

CACNA1F

551

O60840
QLWVDQQKKYHQPQR

FIGNL1

301

Q6PIW4
DPNLVVKINGKHYNW

LPIN3

476

Q9BQK8
EFVGNWNKNAVHVNL

MFGE8

181

Q08431
QDNIQWPTGLAVDYH

LRP1

4041

Q07954
GSNNIYNQIAELWKP

SMPDL3B

146

Q92485
GLNAIQTYVPWNFHE

GLB1

76

P16278
YQAVPNLHKVIVVWN

EXTL2

86

Q9UBQ6
ILGQQVPYATKGNQW

CHI3L1

311

P36222
QPNQINENWKRHSYA

FAM83B

376

Q5T0W9
NDWKRLNTLAHYQVP

PLXNA4

1576

Q9HCM2
NNIQIDKTKPLWHNY

GALK2

96

Q01415
HQWIDLIFGYKQQGP

LRBA

2421

P50851
VYVNHGENLKTEQWP

MED25

431

Q71SY5
QCPHEGNWYLANNRK

LRP2

2676

P98164
VPLQEFAWHQYLQEK

PPIL6

61

Q8IXY8
WHNNIAYIPAQIGAL

LRRC8B

641

Q6P9F7
FDSYHQLQLNPNIWV

RELN

206

P78509
LPFKIAYHLNGNNWV

F2RL2

146

O00254
AFLKVDPAYLQHWQQ

PRDM6

11

Q9NQX0
QPSELIKYWNHLQQN

B3GALT2

386

O43825
MDHQNIPPLNNLQWY

GKN2

86

Q86XP6
AQAQWPHAKGKVYVQ

GLT1D1

121

Q96MS3
NLPWGYKHTLNQIDE

AHSG

51

P02765
LIQHAKDYWQKQPQL

C3orf38

91

Q5JPI3
NNWLNHANYGLIPED

FMO1

261

Q01740
WHVKLQFPQSQAEYI

ZNHIT6

346

Q9NWK9
THWKQALLYLNEPVQ

PRMT6

316

Q96LA8
QYPGSEILWQHNDKN

CD3E

51

P07766
KWQHLVLTYLQQPQG

LYST

1591

Q99698
VNAVHWQPVFYKDGV

ELP2

286

Q6IA86
PEKNKQYHVWFQERN

CCDC168

6726

Q8NDH2
EPVQAAIWQALNHYA

CDC27

6

P30260
EGLKNYVPVNHFWDQ

IFT140

641

Q96RY7
AVQGLLNYINNWHKQ

IZUMO4

166

Q1ZYL8
IGSKNVHWYQQKPGQ

IGLV3-9

46

A0A075B6K5
PQWILEIHYSNFNNL

MOXD2P

301

A6NHM9
VYNQPGHQFCNKWAL

FER1L6

171

Q2WGJ9
QPFSGWLYLQDQNKA

SYT12

266

Q8IV01
GQNYRIVHVQWKPDG

PPP1R3C

251

Q9UQK1
ILSPQGQNGDKWQYL

SYNE2

4441

Q8WXH0
PWINIYAQVQHDKEQ

SORCS3

1151

Q9UPU3
PHNESAWNYLKGILQ

FNTA

271

P49354
WFQLYVHPDLQLNKQ

HAO2

126

Q9NYQ3
YRKQHAQEAIVWQQP

PPP1R16A

361

Q96I34
WEQENHPFNLQYGAQ

SHOC1

1301

Q5VXU9
APAQQVYLQETGNWK

PKHD1

3986

P08F94
QAIQWYQNHQPKSPA

SRP72

431

O76094
YINFEHNVAGQWNPV

NUP160

421

Q12769
RPNWNNEFKQIAYNH

NOX3

511

Q9HBY0
WGNKLQPKGQHYANI

SUMF1

246

Q8NBK3
QPKGQHYANIWQGEF

SUMF1

251

Q8NBK3
TIGANLQKQYENWQP

RPTOR

101

Q8N122
QHSYASLQQNKWPLL

SPG11

906

Q96JI7
QQANHPYWADTVKRL

TOP3B

356

O95985
VKPLEGSQTLYHWQQ

TRAK2

561

O60296
GSQTLYHWQQLAQPN

TRAK2

566

O60296
YHWQQLAQPNLGTIL

TRAK2

571

O60296
KQLGLHPNWQFVDVY

UCHL3

21

P15374
NSIVQIHEKNGWYTP

UBE2Q2

356

Q8WVN8
SLFWYVQHPNKGLQL

TRAV8-2

51

A0A0B4J237
LYRANPHGEWVLKQN

ARHGAP40

606

Q5TG30
PNQLKAWLQQYHNQC

ELAC2

581

Q9BQ52
YVPANSLQQKLSNWG

SPEF1

56

Q9Y4P9
NGNPYVKDLNWIHVQ

KIF20A

336

O95235
RASLEKNPYQAVHQW

TSPAN32

46

Q96QS1
LYPQQITTNQWKNGA

TRMT12

361

Q53H54
GDNHNIDSVIYKWNP

TSPEAR

446

Q8WU66
QPGVQNFLSKQWYGE

TRPM8

671

Q7Z2W7
QAFKPYVDHQGLWID

TEX2

881

Q8IWB9
HPNSINFYSLKQWGN

TBC1D2B

211

Q9UPU7
ISRHGNQYIQVNEPW

MARS1

711

P56192
VGEKLQWFQNHLDPQ

TMA16

51

Q96EY4
KWNNQYIEDEHQNPR

ZNF878

46

C9JN71
EGIPWKHIDYFNNQI

MYO1D

426

O94832
PNYQSIKWQPHQQNK

MYRF

346

Q9Y2G1