| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | monoatomic cation channel activity | SCN10A SLC24A5 TRPM4 CHRNA9 NALCN ANO6 PIEZO1 SCN2A RYR3 TRPM2 SCN8A | 2.55e-10 | 343 | 46 | 11 | GO:0005261 |
| GeneOntologyMolecularFunction | transporter activity | SCN10A SLC24A5 ABCB11 TRPM4 SLC5A12 CHRNA9 ATAD1 ABCD2 NALCN SLCO6A1 ANO6 NDUFS2 PIEZO1 SCN2A RYR3 TRPM2 SCN8A | 1.54e-09 | 1289 | 46 | 17 | GO:0005215 |
| GeneOntologyMolecularFunction | sodium channel activity | 2.00e-09 | 52 | 46 | 6 | GO:0005272 | |
| GeneOntologyMolecularFunction | monoatomic cation transmembrane transporter activity | SCN10A SLC24A5 TRPM4 SLC5A12 CHRNA9 NALCN ANO6 NDUFS2 PIEZO1 SCN2A RYR3 TRPM2 SCN8A | 2.00e-09 | 664 | 46 | 13 | GO:0008324 |
| GeneOntologyMolecularFunction | transmembrane transporter activity | SCN10A SLC24A5 ABCB11 TRPM4 SLC5A12 CHRNA9 ABCD2 NALCN SLCO6A1 ANO6 NDUFS2 PIEZO1 SCN2A RYR3 TRPM2 SCN8A | 3.68e-09 | 1180 | 46 | 16 | GO:0022857 |
| GeneOntologyMolecularFunction | sodium ion transmembrane transporter activity | 4.85e-09 | 171 | 46 | 8 | GO:0015081 | |
| GeneOntologyMolecularFunction | monoatomic ion channel activity | SCN10A SLC24A5 TRPM4 CHRNA9 NALCN ANO6 PIEZO1 SCN2A RYR3 TRPM2 SCN8A | 5.43e-09 | 459 | 46 | 11 | GO:0005216 |
| GeneOntologyMolecularFunction | monoatomic ion transmembrane transporter activity | SCN10A SLC24A5 TRPM4 SLC5A12 CHRNA9 NALCN ANO6 NDUFS2 PIEZO1 SCN2A RYR3 TRPM2 SCN8A | 1.68e-08 | 793 | 46 | 13 | GO:0015075 |
| GeneOntologyMolecularFunction | channel activity | SCN10A SLC24A5 TRPM4 CHRNA9 NALCN ANO6 PIEZO1 SCN2A RYR3 TRPM2 SCN8A | 2.17e-08 | 525 | 46 | 11 | GO:0015267 |
| GeneOntologyMolecularFunction | passive transmembrane transporter activity | SCN10A SLC24A5 TRPM4 CHRNA9 NALCN ANO6 PIEZO1 SCN2A RYR3 TRPM2 SCN8A | 2.21e-08 | 526 | 46 | 11 | GO:0022803 |
| GeneOntologyMolecularFunction | metal ion transmembrane transporter activity | SCN10A SLC24A5 TRPM4 SLC5A12 CHRNA9 NALCN SCN2A RYR3 TRPM2 SCN8A | 8.19e-08 | 465 | 46 | 10 | GO:0046873 |
| GeneOntologyMolecularFunction | inorganic molecular entity transmembrane transporter activity | SCN10A SLC24A5 TRPM4 SLC5A12 CHRNA9 NALCN ANO6 NDUFS2 SCN2A RYR3 TRPM2 SCN8A | 9.74e-08 | 758 | 46 | 12 | GO:0015318 |
| GeneOntologyMolecularFunction | inorganic cation transmembrane transporter activity | SCN10A SLC24A5 TRPM4 SLC5A12 CHRNA9 NALCN NDUFS2 SCN2A RYR3 TRPM2 SCN8A | 1.32e-07 | 627 | 46 | 11 | GO:0022890 |
| GeneOntologyMolecularFunction | voltage-gated sodium channel activity | 3.55e-07 | 26 | 46 | 4 | GO:0005248 | |
| GeneOntologyMolecularFunction | gated channel activity | 8.45e-07 | 334 | 46 | 8 | GO:0022836 | |
| GeneOntologyMolecularFunction | calcium channel activity | 1.15e-05 | 129 | 46 | 5 | GO:0005262 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic cation channel activity | 1.72e-05 | 140 | 46 | 5 | GO:0099094 | |
| GeneOntologyMolecularFunction | calcium ion transmembrane transporter activity | 2.47e-05 | 151 | 46 | 5 | GO:0015085 | |
| GeneOntologyMolecularFunction | ligand-gated calcium channel activity | 4.92e-05 | 31 | 46 | 3 | GO:0099604 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic ion channel activity | 7.96e-05 | 193 | 46 | 5 | GO:0015276 | |
| GeneOntologyMolecularFunction | ligand-gated channel activity | 8.77e-05 | 197 | 46 | 5 | GO:0022834 | |
| GeneOntologyMolecularFunction | sodium ion binding | 4.64e-04 | 14 | 46 | 2 | GO:0031402 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential | 6.91e-04 | 17 | 46 | 2 | GO:0099508 | |
| GeneOntologyMolecularFunction | active transmembrane transporter activity | 7.50e-04 | 477 | 46 | 6 | GO:0022804 | |
| GeneOntologyMolecularFunction | intracellularly gated calcium channel activity | 7.76e-04 | 18 | 46 | 2 | GO:0015278 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity | 8.08e-04 | 182 | 46 | 4 | GO:0005244 | |
| GeneOntologyMolecularFunction | voltage-gated channel activity | 8.42e-04 | 184 | 46 | 4 | GO:0022832 | |
| GeneOntologyMolecularFunction | monocarboxylic acid transmembrane transporter activity | 1.17e-03 | 90 | 46 | 3 | GO:0008028 | |
| GeneOntologyMolecularFunction | alkali metal ion binding | 1.63e-03 | 26 | 46 | 2 | GO:0031420 | |
| GeneOntologyMolecularFunction | calcium-activated cation channel activity | 1.76e-03 | 27 | 46 | 2 | GO:0005227 | |
| GeneOntologyMolecularFunction | monoatomic ion-gated channel activity | 2.31e-03 | 31 | 46 | 2 | GO:0022839 | |
| GeneOntologyMolecularFunction | intracellularly ligand-gated monoatomic ion channel activity | 2.62e-03 | 33 | 46 | 2 | GO:0005217 | |
| GeneOntologyMolecularFunction | organic anion transmembrane transporter activity | 4.57e-03 | 293 | 46 | 4 | GO:0008514 | |
| GeneOntologyMolecularFunction | ABC-type transporter activity | 5.70e-03 | 49 | 46 | 2 | GO:0140359 | |
| GeneOntologyMolecularFunction | ubiquitin protein ligase binding | 7.45e-03 | 337 | 46 | 4 | GO:0031625 | |
| GeneOntologyMolecularFunction | primary active transmembrane transporter activity | 7.98e-03 | 178 | 46 | 3 | GO:0015399 | |
| GeneOntologyMolecularFunction | ubiquitin-like protein ligase binding | 9.17e-03 | 358 | 46 | 4 | GO:0044389 | |
| GeneOntologyBiologicalProcess | sodium ion transport | 6.80e-09 | 275 | 45 | 9 | GO:0006814 | |
| GeneOntologyBiologicalProcess | sodium ion transmembrane transport | 1.46e-08 | 208 | 45 | 8 | GO:0035725 | |
| GeneOntologyBiologicalProcess | monoatomic cation transmembrane transport | SCN10A SLC24A5 TRPM4 CXCR3 CHRNA9 NALCN ANO6 PIEZO1 SCN2A RYR3 TRPM2 SCN8A | 5.47e-07 | 942 | 45 | 12 | GO:0098655 |
| GeneOntologyBiologicalProcess | monoatomic cation transport | SCN10A SLC24A5 TRPM4 CXCR3 SLC5A12 CHRNA9 NALCN ANO6 PIEZO1 SCN2A RYR3 TRPM2 SCN8A | 6.91e-07 | 1157 | 45 | 13 | GO:0006812 |
| GeneOntologyBiologicalProcess | metal ion transport | SCN10A SLC24A5 TRPM4 CXCR3 SLC5A12 CHRNA9 NALCN ANO6 SCN2A RYR3 TRPM2 SCN8A | 1.03e-06 | 1000 | 45 | 12 | GO:0030001 |
| GeneOntologyBiologicalProcess | membrane depolarization during action potential | 1.11e-06 | 36 | 45 | 4 | GO:0086010 | |
| GeneOntologyBiologicalProcess | calcium ion transmembrane transport | 1.85e-06 | 392 | 45 | 8 | GO:0070588 | |
| GeneOntologyBiologicalProcess | monoatomic ion transmembrane transport | SCN10A SLC24A5 TRPM4 CXCR3 CHRNA9 NALCN ANO6 PIEZO1 SCN2A RYR3 TRPM2 SCN8A | 3.21e-06 | 1115 | 45 | 12 | GO:0034220 |
| GeneOntologyBiologicalProcess | inorganic cation transmembrane transport | SCN10A SLC24A5 TRPM4 CXCR3 CHRNA9 NALCN ANO6 SCN2A RYR3 TRPM2 SCN8A | 3.37e-06 | 922 | 45 | 11 | GO:0098662 |
| GeneOntologyBiologicalProcess | monoatomic ion transport | SCN10A SLC24A5 TRPM4 CXCR3 SLC5A12 CHRNA9 NALCN ANO6 PIEZO1 SCN2A RYR3 TRPM2 SCN8A | 4.70e-06 | 1374 | 45 | 13 | GO:0006811 |
| GeneOntologyBiologicalProcess | membrane depolarization | 6.47e-06 | 121 | 45 | 5 | GO:0051899 | |
| GeneOntologyBiologicalProcess | inorganic ion transmembrane transport | SCN10A SLC24A5 TRPM4 CXCR3 CHRNA9 NALCN ANO6 SCN2A RYR3 TRPM2 SCN8A | 8.59e-06 | 1017 | 45 | 11 | GO:0098660 |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential involved in contraction | 1.01e-05 | 62 | 45 | 4 | GO:0086002 | |
| GeneOntologyBiologicalProcess | calcium ion transport | 1.26e-05 | 509 | 45 | 8 | GO:0006816 | |
| GeneOntologyBiologicalProcess | regulation of membrane potential | 2.47e-05 | 559 | 45 | 8 | GO:0042391 | |
| GeneOntologyBiologicalProcess | dendritic cell chemotaxis | 3.41e-05 | 29 | 45 | 3 | GO:0002407 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential | 3.86e-05 | 87 | 45 | 4 | GO:0086001 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell contraction | 5.01e-05 | 93 | 45 | 4 | GO:0086003 | |
| GeneOntologyBiologicalProcess | dendritic cell migration | 6.59e-05 | 36 | 45 | 3 | GO:0036336 | |
| GeneOntologyBiologicalProcess | response to ATP | 9.06e-05 | 40 | 45 | 3 | GO:0033198 | |
| GeneOntologyBiologicalProcess | cardiac epithelial to mesenchymal transition | 9.06e-05 | 40 | 45 | 3 | GO:0060317 | |
| GeneOntologyBiologicalProcess | bundle of His cell action potential | 9.71e-05 | 7 | 45 | 2 | GO:0086043 | |
| GeneOntologyBiologicalProcess | bundle of His cell to Purkinje myocyte signaling | 9.71e-05 | 7 | 45 | 2 | GO:0086028 | |
| GeneOntologyBiologicalProcess | striated muscle contraction | 1.07e-04 | 217 | 45 | 5 | GO:0006941 | |
| GeneOntologyBiologicalProcess | actin-mediated cell contraction | 1.68e-04 | 127 | 45 | 4 | GO:0070252 | |
| GeneOntologyBiologicalProcess | mononuclear cell migration | 2.39e-04 | 258 | 45 | 5 | GO:0071674 | |
| GeneOntologyBiologicalProcess | AV node cell to bundle of His cell signaling | 3.03e-04 | 12 | 45 | 2 | GO:0086027 | |
| GeneOntologyBiologicalProcess | AV node cell action potential | 3.03e-04 | 12 | 45 | 2 | GO:0086016 | |
| GeneOntologyBiologicalProcess | actin filament-based movement | 3.42e-04 | 153 | 45 | 4 | GO:0030048 | |
| GeneOntologyBiologicalProcess | neuronal action potential | 3.52e-04 | 63 | 45 | 3 | GO:0019228 | |
| GeneOntologyBiologicalProcess | cellular response to purine-containing compound | 4.17e-04 | 14 | 45 | 2 | GO:0071415 | |
| GeneOntologyBiologicalProcess | positive regulation of transport | 4.63e-04 | 1081 | 45 | 9 | GO:0051050 | |
| GeneOntologyBiologicalProcess | response to purine-containing compound | 4.66e-04 | 166 | 45 | 4 | GO:0014074 | |
| GeneOntologyBiologicalProcess | cardiac muscle contraction | 4.77e-04 | 167 | 45 | 4 | GO:0060048 | |
| GeneOntologyBiologicalProcess | bundle of His cell to Purkinje myocyte communication | 4.80e-04 | 15 | 45 | 2 | GO:0086069 | |
| GeneOntologyBiologicalProcess | AV node cell to bundle of His cell communication | 4.80e-04 | 15 | 45 | 2 | GO:0086067 | |
| GeneOntologyBiologicalProcess | detection of mechanical stimulus | 5.87e-04 | 75 | 45 | 3 | GO:0050982 | |
| GeneOntologyBiologicalProcess | protein homotetramerization | 6.34e-04 | 77 | 45 | 3 | GO:0051289 | |
| GeneOntologyBiologicalProcess | cellular response to ATP | 9.52e-04 | 21 | 45 | 2 | GO:0071318 | |
| GeneOntologyBiologicalProcess | action potential | 9.54e-04 | 201 | 45 | 4 | GO:0001508 | |
| GeneOntologyBiologicalProcess | myelination | 1.05e-03 | 206 | 45 | 4 | GO:0042552 | |
| GeneOntologyBiologicalProcess | axon ensheathment | 1.10e-03 | 209 | 45 | 4 | GO:0008366 | |
| GeneOntologyBiologicalProcess | ensheathment of neurons | 1.10e-03 | 209 | 45 | 4 | GO:0007272 | |
| GeneOntologyBiologicalProcess | pore complex assembly | 1.14e-03 | 23 | 45 | 2 | GO:0046931 | |
| GeneOntologyBiologicalProcess | regulation of fatty acid beta-oxidation | 1.25e-03 | 24 | 45 | 2 | GO:0031998 | |
| GeneOntologyCellularComponent | monoatomic ion channel complex | 1.15e-07 | 378 | 46 | 9 | GO:0034702 | |
| GeneOntologyCellularComponent | transmembrane transporter complex | SCN10A TRPM4 CHRNA9 NALCN SLCO6A1 ANO6 NDUFS2 SCN2A RYR3 SCN8A | 1.60e-07 | 523 | 46 | 10 | GO:1902495 |
| GeneOntologyCellularComponent | transporter complex | SCN10A TRPM4 CHRNA9 NALCN SLCO6A1 ANO6 NDUFS2 SCN2A RYR3 SCN8A | 2.55e-07 | 550 | 46 | 10 | GO:1990351 |
| GeneOntologyCellularComponent | sodium channel complex | 4.68e-07 | 29 | 46 | 4 | GO:0034706 | |
| GeneOntologyCellularComponent | voltage-gated sodium channel complex | 6.64e-06 | 17 | 46 | 3 | GO:0001518 | |
| GeneOntologyCellularComponent | cation channel complex | 1.22e-05 | 235 | 46 | 6 | GO:0034703 | |
| GeneOntologyCellularComponent | membrane protein complex | SCN10A TGFBR1 TRPM4 VPS11 HM13 CHRNA9 NALCN SLCO6A1 ANO6 NDUFS2 SCN2A RYR3 SCN8A | 1.36e-05 | 1498 | 46 | 13 | GO:0098796 |
| GeneOntologyCellularComponent | synaptic membrane | 3.57e-05 | 583 | 46 | 8 | GO:0097060 | |
| GeneOntologyCellularComponent | node of Ranvier | 8.78e-04 | 20 | 46 | 2 | GO:0033268 | |
| GeneOntologyCellularComponent | cholinergic synapse | 1.06e-03 | 22 | 46 | 2 | GO:0098981 | |
| GeneOntologyCellularComponent | axon initial segment | 1.85e-03 | 29 | 46 | 2 | GO:0043194 | |
| HumanPheno | Neonatal electro-clinical non-motor seizure | 1.31e-04 | 5 | 19 | 2 | HP:0032812 | |
| HumanPheno | Neonatal seizure with electrographic correlate | 1.31e-04 | 5 | 19 | 2 | HP:0032808 | |
| HumanPheno | Neonatal electro-clinical seizure | 1.31e-04 | 5 | 19 | 2 | HP:0032809 | |
| HumanPheno | Neonatal electro-clinical seizure with behavior arrest | 1.31e-04 | 5 | 19 | 2 | HP:0032823 | |
| HumanPheno | Focal head nodding automatism seizure | 1.31e-04 | 5 | 19 | 2 | HP:0032906 | |
| HumanPheno | Normal interictal EEG | 1.96e-04 | 6 | 19 | 2 | HP:0002372 | |
| HumanPheno | Calcaneovalgus deformity | 2.45e-04 | 34 | 19 | 3 | HP:0001848 | |
| HumanPheno | Deformed tarsal bones | 2.67e-04 | 35 | 19 | 3 | HP:0008119 | |
| HumanPheno | Eyelid myoclonia seizure | 2.74e-04 | 7 | 19 | 2 | HP:0032678 | |
| MousePheno | abnormal nervous system electrophysiology | 2.53e-05 | 329 | 38 | 7 | MP:0002272 | |
| Domain | Ion_trans_dom | 1.15e-08 | 114 | 46 | 7 | IPR005821 | |
| Domain | Ion_trans | 1.15e-08 | 114 | 46 | 7 | PF00520 | |
| Domain | Na_channel_asu | 1.66e-06 | 10 | 46 | 3 | IPR001696 | |
| Domain | Na_trans_assoc | 1.66e-06 | 10 | 46 | 3 | IPR010526 | |
| Domain | Na_trans_assoc | 1.66e-06 | 10 | 46 | 3 | PF06512 | |
| Domain | Channel_four-helix_dom | 1.16e-05 | 57 | 46 | 4 | IPR027359 | |
| Domain | - | 1.16e-05 | 57 | 46 | 4 | 1.20.120.350 | |
| Domain | Na_trans_cytopl | 8.85e-05 | 6 | 46 | 2 | PF11933 | |
| Domain | Na_trans_cytopl | 8.85e-05 | 6 | 46 | 2 | IPR024583 | |
| Domain | IQ_motif_EF-hand-BS | 1.41e-03 | 90 | 46 | 3 | IPR000048 | |
| Domain | IQ | 1.55e-03 | 93 | 46 | 3 | PS50096 | |
| Domain | ABC_TM1F | 2.15e-03 | 28 | 46 | 2 | PS50929 | |
| Domain | ABC1_TM_dom | 2.15e-03 | 28 | 46 | 2 | IPR011527 | |
| Domain | ABC_transporter_CS | 4.80e-03 | 42 | 46 | 2 | IPR017871 | |
| Domain | AAA+_ATPase | 5.35e-03 | 144 | 46 | 3 | IPR003593 | |
| Domain | AAA | 5.35e-03 | 144 | 46 | 3 | SM00382 | |
| Domain | ABC_TRANSPORTER_2 | 6.23e-03 | 48 | 46 | 2 | PS50893 | |
| Domain | ABC_tran | 6.23e-03 | 48 | 46 | 2 | PF00005 | |
| Domain | ABC_TRANSPORTER_1 | 6.48e-03 | 49 | 46 | 2 | PS00211 | |
| Domain | ABC_transporter-like | 6.74e-03 | 50 | 46 | 2 | IPR003439 | |
| Domain | - | 9.56e-03 | 746 | 46 | 6 | 3.40.50.300 | |
| Pathway | REACTOME_STIMULI_SENSING_CHANNELS | 4.89e-06 | 99 | 36 | 5 | MM14910 | |
| Pathway | REACTOME_STIMULI_SENSING_CHANNELS | 6.85e-06 | 106 | 36 | 5 | M27200 | |
| Pathway | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | 6.55e-05 | 31 | 36 | 3 | M877 | |
| Pathway | REACTOME_PHASE_0_RAPID_DEPOLARISATION | 7.21e-05 | 32 | 36 | 3 | M27455 | |
| Pathway | REACTOME_ION_CHANNEL_TRANSPORT | 7.89e-05 | 176 | 36 | 5 | MM15718 | |
| Pathway | REACTOME_ION_CHANNEL_TRANSPORT | 9.49e-05 | 183 | 36 | 5 | M997 | |
| Pathway | REACTOME_SENSORY_PERCEPTION_OF_TASTE | 2.30e-04 | 47 | 36 | 3 | M42524 | |
| Pathway | REACTOME_TRANSPORT_OF_SMALL_MOLECULES | 2.58e-04 | 681 | 36 | 8 | MM14985 | |
| Pathway | REACTOME_CARDIAC_CONDUCTION | 3.24e-04 | 130 | 36 | 4 | M27454 | |
| Pathway | REACTOME_TRANSPORT_OF_SMALL_MOLECULES | 4.37e-04 | 736 | 36 | 8 | M27287 | |
| Pathway | WP_DRUG_INDUCTION_OF_BILE_ACID_PATHWAY | 8.42e-04 | 17 | 36 | 2 | M39666 | |
| Pathway | WP_FARNESOID_X_RECEPTOR_PATHWAY | 1.06e-03 | 19 | 36 | 2 | M39411 | |
| Pathway | REACTOME_CLASS_I_PEROXISOMAL_MEMBRANE_PROTEIN_IMPORT | 1.06e-03 | 19 | 36 | 2 | MM15651 | |
| Pathway | REACTOME_CLASS_I_PEROXISOMAL_MEMBRANE_PROTEIN_IMPORT | 1.17e-03 | 20 | 36 | 2 | M27930 | |
| Pubmed | A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain. | 4.61e-08 | 6 | 47 | 3 | 23652591 | |
| Pubmed | 1.93e-07 | 9 | 47 | 3 | 16382098 | ||
| Pubmed | 6.55e-07 | 13 | 47 | 3 | 15123669 | ||
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 38098265 | ||
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 35348308 | ||
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 15760941 | ||
| Pubmed | Deciphering and disrupting PIEZO1-TMEM16F interplay in hereditary xerocytosis. | 1.79e-06 | 2 | 47 | 2 | 38033286 | |
| Pubmed | Sodium channel expression within chronic multiple sclerosis plaques. | 1.79e-06 | 2 | 47 | 2 | 17805013 | |
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 18601978 | ||
| Pubmed | FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels. | 1.79e-06 | 2 | 47 | 2 | 19465131 | |
| Pubmed | Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis. | 1.79e-06 | 2 | 47 | 2 | 23735284 | |
| Pubmed | FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane. | 3.02e-06 | 468 | 47 | 7 | 31056421 | |
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 32845893 | ||
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 16033895 | ||
| Pubmed | Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons. | 5.36e-06 | 3 | 47 | 2 | 29991598 | |
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 28518218 | ||
| Pubmed | Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain. | 5.36e-06 | 3 | 47 | 2 | 29497094 | |
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 17928448 | ||
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 38514708 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 17537961 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 35031483 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 29578003 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 21156207 | ||
| Pubmed | 1.78e-05 | 5 | 47 | 2 | 24077057 | ||
| Pubmed | 1.78e-05 | 5 | 47 | 2 | 17724025 | ||
| Pubmed | 2.67e-05 | 6 | 47 | 2 | 16029194 | ||
| Pubmed | Are voltage-dependent ion channels involved in the endothelial cell control of vasomotor tone? | 2.67e-05 | 6 | 47 | 2 | 17513486 | |
| Pubmed | 2.67e-05 | 6 | 47 | 2 | 23711479 | ||
| Pubmed | ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1. | 2.83e-05 | 1201 | 47 | 9 | 35696571 | |
| Pubmed | Diagnostic yield of genetic testing in epileptic encephalopathy in childhood. | 3.74e-05 | 7 | 47 | 2 | 25818041 | |
| Pubmed | Evidence for the involvement of ASIC3 in sensory mechanotransduction in proprioceptors. | 4.98e-05 | 8 | 47 | 2 | 27161260 | |
| Pubmed | 6.40e-05 | 9 | 47 | 2 | 17554679 | ||
| Pubmed | 6.40e-05 | 9 | 47 | 2 | 15746173 | ||
| Pubmed | 9.75e-05 | 11 | 47 | 2 | 37322017 | ||
| Pubmed | 9.75e-05 | 11 | 47 | 2 | 19096130 | ||
| Pubmed | Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice. | 1.17e-04 | 12 | 47 | 2 | 30175250 | |
| Pubmed | 1.17e-04 | 12 | 47 | 2 | 19156209 | ||
| Pubmed | Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons. | 1.17e-04 | 12 | 47 | 2 | 19850157 | |
| Pubmed | WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination. | 1.38e-04 | 13 | 47 | 2 | 16723544 | |
| Pubmed | 1.56e-04 | 378 | 47 | 5 | 34315543 | ||
| Pubmed | A genome-wide association study identifies two new risk loci for Graves' disease. | 2.12e-04 | 16 | 47 | 2 | 21841780 | |
| Pubmed | 2.40e-04 | 17 | 47 | 2 | 24647736 | ||
| Pubmed | Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics. | 2.59e-04 | 422 | 47 | 5 | 27342126 | |
| Pubmed | 2.70e-04 | 18 | 47 | 2 | 37321992 | ||
| Pubmed | 2.70e-04 | 18 | 47 | 2 | 19308021 | ||
| Pubmed | A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins. | 3.99e-04 | 719 | 47 | 6 | 35337019 | |
| Pubmed | Mapping the expression of transient receptor potential channels across murine placental development. | 4.84e-04 | 24 | 47 | 2 | 33884443 | |
| Pubmed | 4.84e-04 | 24 | 47 | 2 | 20301690 | ||
| Pubmed | 5.26e-04 | 25 | 47 | 2 | 16382100 | ||
| Pubmed | Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins. | 5.56e-04 | 499 | 47 | 5 | 22810586 | |
| Pubmed | Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network. | 5.74e-04 | 282 | 47 | 4 | 35007762 | |
| Pubmed | 6.14e-04 | 27 | 47 | 2 | 25133637 | ||
| Pubmed | 6.14e-04 | 27 | 47 | 2 | 16460286 | ||
| Pubmed | A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. | 7.05e-04 | 298 | 47 | 4 | 32353859 | |
| Pubmed | 7.79e-04 | 1487 | 47 | 8 | 33957083 | ||
| Pubmed | 9.19e-04 | 33 | 47 | 2 | 19834762 | ||
| Pubmed | 9.94e-04 | 568 | 47 | 5 | 37774976 | ||
| Pubmed | 1.05e-03 | 147 | 47 | 3 | 29576527 | ||
| Interaction | SCN11A interactions | 4.65e-06 | 15 | 45 | 3 | int:SCN11A | |
| Cytoband | 12q12 | 1.08e-03 | 47 | 47 | 2 | 12q12 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr12q12 | 1.93e-03 | 63 | 47 | 2 | chr12q12 | |
| Cytoband | 1p31.1 | 2.44e-03 | 71 | 47 | 2 | 1p31.1 | |
| GeneFamily | Sodium voltage-gated channel alpha subunits | 5.54e-07 | 9 | 35 | 3 | 1203 | |
| GeneFamily | Transient receptor potential cation channels | 1.33e-03 | 28 | 35 | 2 | 249 | |
| GeneFamily | Ubiquitin specific peptidases | 5.25e-03 | 56 | 35 | 2 | 366 | |
| Coexpression | GSE23321_CENTRAL_MEMORY_VS_NAIVE_CD8_TCELL_UP | 2.84e-05 | 199 | 47 | 5 | M8435 | |
| Coexpression | GSE27786_CD8_TCELL_VS_NKTCELL_UP | 2.91e-05 | 200 | 47 | 5 | M4839 | |
| ToppCell | LPS-antiTNF-Stromal_mesenchymal-Fibroblasts-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 1.94e-05 | 151 | 47 | 4 | f13a117ae26ae525da4f3e837d8f204d00dc6ee3 | |
| ToppCell | renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 2.38e-05 | 159 | 47 | 4 | fd7db2f7328cfefdc3ada2af91006d5a91d137e1 | |
| ToppCell | renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 2.38e-05 | 159 | 47 | 4 | aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914 | |
| ToppCell | renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 2.38e-05 | 159 | 47 | 4 | 8bbdef1e927f3130b578d7d7c5ff38bbe06fab63 | |
| ToppCell | renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 2.88e-05 | 167 | 47 | 4 | 0130743084dbcb20e10f96715d30961122150cbf | |
| ToppCell | renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 2.88e-05 | 167 | 47 | 4 | 7bcae3797d3a0811e7f39885afdfd29ec517f11b | |
| ToppCell | renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 2.88e-05 | 167 | 47 | 4 | c6f0209a1ad797631fdfa3efab6db6b1d3e8e315 | |
| ToppCell | Epithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor | 4.03e-05 | 182 | 47 | 4 | 57bf4ffb304324e2e392e196336a530d9f78fe0d | |
| ToppCell | 5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 4.12e-05 | 183 | 47 | 4 | 764ea07621f77fbd13a877aed5806ae2b3dfb43e | |
| ToppCell | 5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 4.12e-05 | 183 | 47 | 4 | 38a54216458ad57f356bb4ddf272e1af8036ddeb | |
| ToppCell | facs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 4.30e-05 | 185 | 47 | 4 | 53854a9ec87c24c360541c83d86d8fafb303ad58 | |
| ToppCell | facs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 4.30e-05 | 185 | 47 | 4 | a61fc7a3700a1efcf640bef7680c0443ee148a46 | |
| ToppCell | BAL-Control-Myeloid-MoAM-MoAM4|Control / Location, Disease Group, Cell group, Cell class (2021.03.09) | 4.30e-05 | 185 | 47 | 4 | 274b8acccdfe434d14af4cb32fb615c06ec98435 | |
| ToppCell | BAL-Control-Myeloid-MoAM-MoAM4-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09) | 4.30e-05 | 185 | 47 | 4 | b640d9ed6a1e6aa595053065bb992efc0402353e | |
| ToppCell | Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types | 4.39e-05 | 186 | 47 | 4 | 948815663c212c4311329d503b5991cbbbff9808 | |
| ToppCell | Control-Myeloid-MoAM3,_VCAN|Myeloid / Condition, Lineage and Cell class | 4.39e-05 | 186 | 47 | 4 | 0bf16ac48931b62bb3c33d63ff4279654148e293 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 4.39e-05 | 186 | 47 | 4 | 7278a1a1bf9bb27aeb03852134defb31b62f30d6 | |
| ToppCell | 10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 4.48e-05 | 187 | 47 | 4 | 2a7226adb4d15b92936603bdf05421c50b21f003 | |
| ToppCell | wk_15-18-Hematologic-Myeloid-Basophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung | 4.58e-05 | 188 | 47 | 4 | 3638d85452de15a060146628fbbad9d2a36feb13 | |
| ToppCell | Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 4.58e-05 | 188 | 47 | 4 | c4c3b21ab723b0e9beff9ec84f8d68485f771528 | |
| ToppCell | Control-Myeloid-MoAM4|Control / Disease group,lineage and cell class (2021.01.30) | 4.97e-05 | 192 | 47 | 4 | 1da7c303a2e36af4a9d8ec30a11380d9b1897922 | |
| ToppCell | renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 5.17e-05 | 194 | 47 | 4 | 04bfc555743f7d8821439d05ae442d15e9886c59 | |
| ToppCell | renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 5.17e-05 | 194 | 47 | 4 | 4579b4a44f7c731553a284843c296866027d7c0e | |
| ToppCell | kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 5.71e-05 | 199 | 47 | 4 | 5059a1d4df7d9989c922007a8dcba98b1f5687d5 | |
| ToppCell | kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 5.71e-05 | 199 | 47 | 4 | a4ebb0598e9a0c9f6e39a0db6d0623654c2a7d88 | |
| ToppCell | Tracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | 5.82e-05 | 200 | 47 | 4 | 0eb9ad8c0373bcc62029ec21c590ed03aaacd039 | |
| Drug | APETx2 protein, Anthopleura elegantissima | 3.29e-08 | 4 | 47 | 3 | ctd:C501880 | |
| Drug | APETx1, Anthopleura elegantissima | 1.64e-07 | 6 | 47 | 3 | ctd:C475726 | |
| Drug | 2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate | 4.58e-07 | 8 | 47 | 3 | ctd:C489827 | |
| Disease | generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology) | 3.95e-07 | 10 | 45 | 3 | DOID:0111294 (implicated_via_orthology) | |
| Disease | Dravet syndrome (implicated_via_orthology) | 3.95e-07 | 10 | 45 | 3 | DOID:0080422 (implicated_via_orthology) | |
| Disease | generalized epilepsy with febrile seizures plus (implicated_via_orthology) | 7.22e-07 | 12 | 45 | 3 | DOID:0060170 (implicated_via_orthology) | |
| Disease | Benign familial infantile epilepsy | 6.82e-06 | 3 | 45 | 2 | cv:C5575231 | |
| Disease | Familial benign neonatal epilepsy | 3.40e-05 | 6 | 45 | 2 | C0220669 | |
| Disease | trans fatty acid measurement, trans/trans-18:2 fatty acid measurement | 6.14e-04 | 24 | 45 | 2 | EFO_0006821, EFO_0006826 | |
| Disease | Brugada Syndrome (disorder) | 6.14e-04 | 24 | 45 | 2 | C1142166 | |
| Disease | Colorectal Carcinoma | 6.56e-04 | 702 | 45 | 6 | C0009402 | |
| Disease | maximal oxygen uptake measurement | 7.22e-04 | 26 | 45 | 2 | EFO_0004887 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| LLYAFVGVKFRERMW | 316 | P49682 | |
| ARVYNMFWVFDEVKR | 421 | Q9UBJ2 | |
| MFWVFDEVKRGIYKR | 426 | Q9UBJ2 | |
| IGFKFTFFVSIMIYW | 26 | Q9NPC4 | |
| KFYFRRIMRMEIGWF | 176 | O95342 | |
| VAKVIDRFFMWIFFI | 451 | Q9UGM1 | |
| VFMVWYEFCSDFKTI | 1351 | Q68DA7 | |
| FAVFMGVWVTLFLEF | 381 | Q4KMQ2 | |
| PVFFAFRMRFYVAWI | 236 | Q96N66 | |
| FIYDVFWVFGTNVMV | 216 | Q8TCT9 | |
| EKSEYWFFVIFMLLR | 341 | Q96M69 | |
| YMAARVVFIKWIVTF | 296 | Q2PPJ7 | |
| KGFWTEFMGRVFKYL | 41 | Q8TCD6 | |
| FWLFEEREKMFEFYE | 201 | O75306 | |
| AKFITFGMLIYFIAW | 781 | Q5T6X5 | |
| VWMDEFKDFFYIISP | 371 | Q8IUC8 | |
| EREFQMWAPKFYVVT | 801 | Q12873 | |
| FFFGRLDYQDKWVRM | 216 | O00754 | |
| KVLFYRWLVAMFDFI | 161 | Q92674 | |
| MKYLFFSWLVVFVGS | 26 | Q5T7M9 | |
| FVSVYKINKMAFWVG | 41 | Q14CX5 | |
| FAVLMWVFTYVGALF | 1121 | Q9NQC3 | |
| FIAFYGDRKKVIWFV | 161 | Q86UG4 | |
| WAVMDVVNYFRTVGF | 51 | Q5VXD3 | |
| VLVSGYFFWKNMKFI | 126 | Q06520 | |
| FKRADIYAMGLVFWE | 396 | P36897 | |
| IWFTVYKGAEVAHFM | 91 | P21589 | |
| FGAVTYFTIKWMVDA | 26 | Q8NBU5 | |
| RVPAFGWVMFVAVFY | 66 | Q8IZV2 | |
| YATGKEMRIIDFFWT | 76 | Q9NYW3 | |
| MAAYLQWRRFVFFDK | 1 | Q9H270 | |
| VKVLFSFFWMLFVGL | 4181 | Q15413 | |
| RVFTFIFVFEMLLKW | 1191 | Q9Y5Y9 | |
| IFVFEMLLKWVAYGF | 1196 | Q9Y5Y9 | |
| MKDVFFFLFLLAVWV | 931 | O94759 | |
| EMLLKWVAYGFQVYF | 1256 | Q99250 | |
| AETEKFWMFYRFDAI | 51 | Q96B77 | |
| KNYFVITFFMSAIWI | 331 | Q71RS6 | |
| EMLLKWTAYGFVKFF | 1246 | Q9UQD0 | |
| DVQYGMWFSRKFLDF | 171 | Q9UBV4 | |
| DMLKVAVFRYLFWLV | 1156 | Q92508 | |
| MEVKNFAVWDYVVFA | 1 | Q1EHB4 | |
| MMKDVFFFLFFLGVW | 926 | Q8TD43 | |
| GWIAFFMEYVKRFVV | 541 | Q8TEY7 | |
| WKTELFFIGFIIMGF | 316 | Q9NS93 | |
| FFFQTKIRKWMYFDD | 306 | Q70EL1 | |
| IMGYKFLRIVVWFVS | 411 | P16473 | |
| TKYARWIAFTGMILF | 96 | Q8NHV5 | |
| SYVKDRWCVFDGFMV | 101 | Q8IZF0 |