Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainAnk_3

ANKRD62 ANK3

1.80e-0410382PF13606
Domainfn3

PHYHIP PTPRC PHYHIPL

4.33e-03162383PF00041
DomainFN3

PHYHIP PTPRC PHYHIPL

6.25e-03185383SM00060
DomainFN3

PHYHIP PTPRC PHYHIPL

7.64e-03199383PS50853
DomainFN3_dom

PHYHIP PTPRC PHYHIPL

8.74e-03209383IPR003961
Pubmed

Nucleophosmin/B23 activates Aurora A at the centrosome through phosphorylation of serine 89.

NPM1 AURKA

1.36e-06241222451695
Pubmed

AURKA inhibition induces Ewing's sarcoma apoptosis and ferroptosis through NPM1/YAP1 axis.

NPM1 AURKA

4.06e-06341238287009
Pubmed

Phosphorylation of multifunctional nucleolar protein nucleophosmin (NPM1) by aurora kinase B is critical for mitotic progression.

NPM1 AURKA

4.06e-06341224857377
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

ZNF638 NPM1 AURKA FAM193A AP2A2 TTC3 MUTYH KTN1

1.07e-0592541828986522
Pubmed

Gadd45a interacts with aurora-A and inhibits its kinase activity.

NPM1 AURKA

1.35e-05541216772293
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NPM1 ISG20L2 NRXN3 FAM98B BRD2 AP2A2 TTC3 KTN1 ZNF292

3.72e-05144241935575683
Pubmed

Card9 protects fungal peritonitis through regulating Malt1-mediated activation of autophagy in macrophage.

NPM1 AP2A2

8.88e-051241235850054
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

PHYHIP NPM1 ANK3 AP2A2 PHYHIPL

1.08e-0440341530562941
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

ZNF638 NPM1 AURKA SECISBP2 SPATS2L BRD2 ANK3 TTC3

1.14e-04129341815342556
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

ZNF638 NPM1 AURKA ISG20L2 SPATS2L FAM98B BRD2

1.42e-0498941736424410
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

SECISBP2 SPATS2L FAM193A TTC3 KTN1 ZNF292

1.93e-0472441636232890
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ZNF638 SECISBP2 FAM3C FAM193A TEX9 KTN1

2.06e-0473341634672954
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ZNF638 SECISBP2 FAM193A ANK3

2.60e-0426341434702444
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

NPM1 AURKA FAM98B BRD2 KTN1

4.11e-0453841528524877
Pubmed

Differential expression of paralog RNA binding proteins establishes a dynamic splicing program required for normal cerebral cortex development.

KANSL1L NRXN3

5.03e-042841238324473
Pubmed

STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.

ISG20L2 SPATS2L AP2A2 KTN1

5.20e-0431641431665637
Pubmed

FCH domain only-2 organizes clathrin-coated structures and interacts with Disabled-2 for low-density lipoprotein receptor endocytosis.

AURKA AP2A2

6.17e-043141222323290
Pubmed

Functional proteomics mapping of a human signaling pathway.

SECISBP2 PTPRC ANK3 AP2A2 TTC3

6.30e-0459141515231748
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

NPM1 SPATS2L FAM98B BRD2 KTN1

6.79e-0460141533658012
Pubmed

The human CENP-A centromeric nucleosome-associated complex.

NPM1 CENPI

8.33e-043641216622419
Pubmed

Genomic analysis of mouse retinal development.

AURKA SECISBP2 FAM3C CDK5R1 BRD2 PHYHIPL

1.09e-03100641615226823
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

NPM1 SECISBP2 SPATS2L FAM193A AP2A2

1.16e-0367841530209976
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF708 ZNF311 ZNF800 ZNF292

5.94e-0371819428
GeneFamilyFibronectin type III domain containing

PTPRC PHYHIPL

1.21e-02160192555
GeneFamilyAnkyrin repeat domain containing

ANKRD62 ANK3

2.63e-02242192403
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1

ZNF638 NPM1 ZNF800 TEX9 PHYHIPL KTN1 CENPI

5.84e-07259417Facebase_RNAseq_e8.5_Floor Plate_1000_K1
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

ZNF638 NPM1 ZNF800 FAM98B TEX9 TTC3 PHYHIPL KTN1

6.79e-06532418Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5

NPM1 FAM98B TEX9 PHYHIPL KTN1

4.41e-05204415Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

NPM1 ZNF800 NRXN3 FAM98B FAM193A PARPBP PHYHIPL MUTYH KTN1 CENPI ZNF292

7.18e-0514594111facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000

ZNF638 NPM1 AURKA ZNF800 TEX9 AP2A2 PHYHIPL KTN1 CENPI

9.41e-05994419Facebase_RNAseq_e8.5_Floor Plate_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#4

FAM98B TEX9 PHYHIPL KTN1

9.49e-05124414Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K4
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

NPM1 ZNF800 FAM98B FAM193A PARPBP PHYHIPL MUTYH KTN1 CENPI ZNF292

1.06e-0412574110facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#4

ZNF800 TEX9 PHYHIPL KTN1

1.48e-04139414Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#4

ZNF800 TEX9 PHYHIPL KTN1 ZNF292

2.61e-04298415Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

NPM1 FAM98B FAM193A TEX9 ZNF292

3.17e-04311415Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500

NPM1 ZNF800 NRXN3 TEX9 PHYHIPL KTN1

3.43e-04493416Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#1_top-relative-expression-ranked_200

SAMD9L CCDC198

4.29e-0416412gudmap_developingKidney_e15.5_Medullary collecting duct_200_k1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

ZNF800 FAM98B TEX9 KTN1

5.05e-04192414Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

NPM1 ZNF800 FAM98B FAM193A TEX9 PHYHIPL KTN1 ZNF292

5.22e-04989418Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
ToppCelldroplet-Lung-nan-21m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHYHIP DNAH5 C1orf87 PPIL6

2.00e-051754143ed22ea41810e73c02db4f2d03745e4ce7e43bb1
ToppCelldroplet-Lung-nan-21m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHYHIP DNAH5 C1orf87 PPIL6

2.00e-051754148fb1e5f6aa68274adf322401db8c7b80e8c554d7
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPDYA NRXN3 GALNT5 ANK3

2.28e-051814140513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF638 SAMD9L PTPRC KTN1

2.33e-05182414f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5|Striatum / BrainAtlas - Mouse McCarroll V32

NPM1 AURKA PARPBP CENPI

2.38e-05183414f20b0d71f857ac35868fd80531050ad8b6091716
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF638 SAMD9L PTPRC KTN1

2.44e-051844141154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF638 SAMD9L PTPRC KTN1

2.49e-051854147adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PHYHIP CDK5R1 NRXN3 TTC3

2.54e-051864143f889083fcffe516388e9b03a5e23af2010ced33
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L SPATS2L CCDC198 PHYHIPL

2.59e-051874149d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCelldroplet-Lung-LUNG-1m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 DNAH5 PHYHIPL PPIL6

2.59e-051874146288da8cdd450c58df00ebcfcc118f01fab7e610
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AURKA PTPRC PARPBP CENPI

2.59e-0518741473931a5ea73799095daff100b5f18853c57c74dc
ToppCellfacs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AURKA PARPBP MUTYH CENPI

2.71e-05189414bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCellfacs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AURKA PARPBP MUTYH CENPI

2.71e-0518941496f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

TEX9 DNAH5 C1orf87 PPIL6

2.88e-05192414354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PHYHIP CDK5R1 NRXN3 TTC3

2.88e-051924144c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

TEX9 DNAH5 C1orf87 PPIL6

2.94e-05193414a0baa8be6f590b2031fede22be588715ae458e93
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

TEX9 DNAH5 C1orf87 PPIL6

3.00e-05194414958e648138676d46698090b4046cb484083ae449
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TEX9 DNAH5 C1orf87 PPIL6

3.00e-051944141ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TEX9 DNAH5 C1orf87 PPIL6

3.06e-051954143486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TEX9 DNAH5 C1orf87 PPIL6

3.06e-05195414e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L CCDC198 ANK3 PHYHIPL

3.12e-051964146ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TEX9 DNAH5 C1orf87 PPIL6

3.12e-0519641427b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZNF638 NPM1 SAMD9L PTPRC

3.24e-051984144c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TEX9 DNAH5 C1orf87 PPIL6

3.24e-05198414ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

CDK5R1 NRXN3 TTC3 ZNF292

3.24e-05198414de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellmedial-Epithelial-Ciliated-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TEX9 DNAH5 C1orf87 PPIL6

3.31e-05199414526002f16bbf61cf086278d45a401cc0b0b757a8
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

SECISBP2 TTC3 KTN1 ZNF292

3.31e-05199414c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Neuronal|1_mon / Sample Type, Dataset, Time_group, and Cell type.

CDK5R1 ANK3 TTC3 PHYHIPL

3.31e-05199414f94307958cead25d38103fcbb35fa45011de1687
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

SPATS2L TTC3 KTN1 ZNF292

3.31e-0519941419674e1eaeb51e4196d847cb62aa437c852951d3
ToppCellmedial-Epithelial-Ciliated|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TEX9 DNAH5 C1orf87 PPIL6

3.31e-05199414a2daa42b100c422dc8c04fb7d2ebf54293eef574
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

SECISBP2 TTC3 KTN1 ZNF292

3.31e-0519941453ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

TTC3 DNAH5 KTN1 ZNF292

3.31e-05199414fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellmedial-2-Epithelial-Ciliated|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TEX9 DNAH5 C1orf87 PPIL6

3.31e-05199414c02f04a5aa79ee0cf427f6e94b93ceab38ebbcd7
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

SPATS2L TTC3 KTN1 ZNF292

3.31e-05199414a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TEX9 DNAH5 C1orf87 PPIL6

3.37e-05200414f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

TEX9 DNAH5 C1orf87 PPIL6

3.37e-05200414d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

TEX9 DNAH5 C1orf87 PPIL6

3.37e-05200414f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal|10w / Sample Type, Dataset, Time_group, and Cell type.

CDK5R1 NRXN3 ANK3 TTC3

3.37e-05200414979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TEX9 DNAH5 C1orf87 PPIL6

3.37e-052004144992dbf0514d674017315dbd20d91dfec0c608e9
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TEX9 DNAH5 C1orf87 PPIL6

3.37e-05200414cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Ccnb1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AURKA PARPBP CENPI

2.27e-04129413ff74d159034a09f7b174da18bfb9a26936252b4c
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Cdc20)|Hippocampus / BrainAtlas - Mouse McCarroll V32

AURKA PARPBP CENPI

2.37e-04131413f9fb8d74ca720b81fd5910cc975510359a8ef751
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AURKA FAM98B CENPI

3.13e-04144413f6061dd965a2b2fe6ad864f8aecc06d2e74881ce
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

AURKA PARPBP CENPI

3.39e-04148413b9d3421c2eb8e748e9508c1cbd1cb4f96e23db5a
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Hippocampus / BrainAtlas - Mouse McCarroll V32

AURKA PARPBP CENPI

3.39e-041484132a7671dc27afbdf6a92d976c5f2b728bd18dd609
ToppCellSubstantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PTPRC PARPBP CENPI

3.53e-04150413edbc1d29d213bf5908592135700e0d80e123c923
ToppCellSubstantia_nigra-Hematopoietic-MICROGLIA|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PTPRC PARPBP CENPI

3.53e-04150413d44c02402e59a45e40b8fffbe71284032b5e7c92
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|368C / Donor, Lineage, Cell class and subclass (all cells)

CDK5R1 PTPRC DYRK1B

3.53e-04150413c843bcf98c5fad2ca4339602f721f3fb782ae353
ToppCellSubstantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PTPRC PARPBP CENPI

3.53e-0415041301c526e1e3007e71e416c317549fddd2919b14e9
ToppCellSubstantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PTPRC PARPBP CENPI

3.53e-04150413b7f5bf9af7ed50aad4da1c71d37b8b9709e6ce85
ToppCellSubstantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PTPRC PARPBP CENPI

3.53e-04150413e020dbcf85c0ba7ad667b8bbeb6bbcfc135c9bb7
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRC PARPBP CENPI

3.60e-04151413f13a117ae26ae525da4f3e837d8f204d00dc6ee3
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

AURKA PARPBP CENPI

3.74e-04153413d7635f3d4831c02a94f53afc674847d5b51453be
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

AURKA PARPBP CENPI

3.74e-04153413e50d20f9e553b8c3e10e187770d8abe1a43d109e
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

AURKA PARPBP CENPI

3.74e-0415341354a941950bbb848077c7bd5726da9e4b3244bd38
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

AURKA PARPBP CENPI

3.74e-0415341369a8550418ba0fc908a84b3b85761abb6e8ca4c0
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

SAMD9L ANK3 DNAH5

3.88e-041554139cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AURKA PARPBP CENPI

3.96e-04156413b3f10cd044f24807576e7d56e51df7064dbf6c50
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

AURKA PARPBP CENPI

4.34e-041614130dd1401b4c990d49fccb702a9f9867590a58e203
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

AURKA PARPBP CENPI

4.34e-04161413b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

AURKA PARPBP CENPI

4.34e-04161413efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

AURKA PARPBP CENPI

4.34e-0416141328d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4|Lung / Manually curated celltypes from each tissue

ANK3 DNAH5 NALF2

4.42e-0416241391cc14aec8d580cf97a1929bc1acb00fcbcdb57a
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

ZNF708 PTPRC ANK3

4.42e-04162413b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

DNAH5 C1orf87 PPIL6

4.58e-04164413fd30c55d0d75ef8b9396435d836187168095152b
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AURKA PTPRC PARPBP

4.66e-041654131dcd6b8aa192baeaa1f7bb334843edab6049b96f
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

FAM3C SAMD9L GALNT5

4.66e-041654138003fd2aa3f5c9d0e99054af4ad2d79a4a3c4829
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AURKA PARPBP CENPI

4.66e-04165413eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

CDK5R1 ANK3 DNAH5

4.66e-041654139795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISG20L2 SPATS2L DNAH5

4.66e-041654131703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AURKA PARPBP CENPI

4.74e-041664132642544070564debe2deb2938d2c33997bf5ef02
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

TEX9 DNAH5 PPIL6

4.83e-0416741326cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SECISBP2 ANK3 TTC3

4.83e-04167413ced6ed9b412739c6ced622523347c10295edbf53
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AURKA PARPBP CENPI

4.91e-04168413d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AURKA PARPBP CENPI

5.00e-04169413b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AURKA PARPBP CENPI

5.00e-04169413e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRC PARPBP CENPI

5.00e-0416941354b13ab02b4c187f4754045ecfcf409749e7ccc0
ToppCellCiliated_cells-A-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

DNAH5 C1orf87 PPIL6

5.08e-041704133d3a03979014df3a05c49be18010c6b94d786707
ToppCellhealthy_donor-Myeloid-Monocytic-Developing_Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

AURKA SPATS2L CENPI

5.08e-04170413cfd7f29805b7c51666b0eaf269c36c96b8765a1a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AURKA PARPBP CENPI

5.08e-0417041321bfe070e63722672176052b386167ea4c3dc4e5
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPATS2L AP2A2 PPIL6

5.08e-041704138465c3069bbc08705d070927e712b6bc85ac7c5b
ToppCellCiliated_cells-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

DNAH5 C1orf87 PPIL6

5.08e-041704138b7ef1464ea589886b575ebad5447b085cbdcdba
ToppCell3'-Adult-Distal_Rectal-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM3C NRXN3 GALNT5

5.17e-041714130597339618fb4d416d55c538eceb353218a55002
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRC PARPBP CENPI

5.17e-0417141355c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCell3'-Adult-Distal_Rectal-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM3C NRXN3 GALNT5

5.17e-041714130de81d12a8000f2c59cdb214e67dc526d18098fe
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD9L CCDC198 PTPRC

5.26e-041724131f335ccb92b22d0412954e8fc3af212f96410b67
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NPM1 SPATS2L PTPRC

5.26e-041724139497948bbe53fb88c6ff6b347f743d456da587e5
ToppCellInfluenza_Severe-CD4+_Tcm|Influenza_Severe / Disease group and Cell class

PHYHIP NPM1 ANK3

5.26e-0417241347865a04968ca28c6ff125159d9a23e37c8b8af1
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SPDYA PARPBP CENPI

5.26e-04172413e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCelldroplet-Liver-nan-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD9L CCDC198 PTPRC

5.26e-04172413bb96c896d125e10b71e94e2bdad243899045af5c
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-5|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

PHYHIP C1orf87 PPIL6

5.26e-041724136b8a8d3b97c10b9d092307eed3cacbd2745df185
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AURKA TEX9 PARPBP

5.35e-04173413f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANK3 DNAH5 C1orf87

5.35e-04173413a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AURKA PARPBP CENPI

5.44e-0417441384da9faff088d05233183b425385beb054c92d1b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRC PARPBP CENPI

5.44e-041744137b318796728001c17b4043d2b033330c7be40c78
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AURKA PARPBP CENPI

5.44e-04174413dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AURKA TEX9 PARPBP

5.53e-0417541315c69dd5635c9251c535f1e22467712e9667ae92
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AURKA PARPBP CENPI

5.53e-04175413876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRC PARPBP CENPI

5.53e-04175413f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPDYA MUTYH CENPI

5.62e-041764133766e0533b103ec92ac75eba3df02e287efc53fa
Diseasemyelodysplastic syndrome (implicated_via_orthology)

NPM1 SAMD9L

1.77e-0415392DOID:0050908 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

AURKA GALNT5 PTPRC TTC3 SLCO1B1 C1orf87 KTN1

4.60e-041074397C0006142
Diseaseneutrophil-to-lymphocyte ratio

ZNF800 BRD2 ZNF292

1.88e-03185393EFO_0008447
Diseasesusceptibility to bacterial meningitis measurement

ANK3 DNAH5

2.16e-0352392EFO_0008411
DiseaseMetastatic melanoma

AURKA DYRK1B

2.33e-0354392C0278883
Diseasemean corpuscular hemoglobin concentration

ZNF638 AURKA ZNF800 PTPRC TEX9 SLCO1B1

3.08e-031105396EFO_0004528
DiseaseNonorganic psychosis

PTPRC ANK3

3.78e-0369392C0349204

Protein segments in the cluster

PeptideGeneStartEntry
QNSKNAKDKNLKRHS

CDK5R1

31

Q15078
AQKLVSSHKPVQNQK

AURKA

61

O14965
TKSQSEHQNLQGKKK

ANKRD62

466

A6NC57
NKQKKQLRNPHKTFD

DUS1L

371

Q6P1R4
NNNKKQLNHIKDEKS

FAM193A

1106

P78312
PQDSSNKKEKKVLNH

DYRK1B

76

Q9Y463
KKHPENNQKSENNQK

C1orf87

86

Q8N0U7
QEPPKSKKVQHSNAK

AP2A2

291

O94973
AKNAQKSNQNGKDSK

NPM1

201

P06748
HKNAKIPKKSNDSQN

PARPBP

531

Q9NWS1
EEKNKRQNHSKKESP

LUZP4

46

Q9P127
KTKSPFEQHIKNNKD

FAM3C

191

Q92520
NSTLNKHNENYKQKK

KANSL1L

86

A0AUZ9
SQKKSSKKNHPQKNA

ISG20L2

141

Q9H9L3
SKKNHPQKNAPQNST

ISG20L2

146

Q9H9L3
KNKKKEIQNGNLHES

KTN1

61

Q86UP2
KKFKESEAPKTHQQQ

NALF2

371

O75949
KSAAENLKNNHPSKF

PPIL6

41

Q8IXY8
NKTKTQSKEVNANKH

GALNT5

256

Q7Z7M9
TSAQHAEKDNQMKPK

ANK3

2311

Q12955
QNKKHKNSQLDKNSE

FAM98B

131

Q52LJ0
KVKQDPSNSKNISKH

CENPI

31

Q92674
NKQSPRDHKAKKTLQ

CCDC198

181

Q9NVL8
FHKTKQKLKQNPNAK

DNAH5

446

Q8TE73
DLNKKENKNSNKFKH

PHYHIPL

86

Q96FC7
ENKNSNKFKHKDVPT

PHYHIPL

91

Q96FC7
FEKNTHNNNKSKRPK

SPDYA

46

Q5MJ70
NDHQSNKGKKTNFLK

SPDYA

286

Q5MJ70
KNNKRKRSKSKQHQG

SPATS2L

66

Q9NUQ6
DNSKPSKTEHQKNPK

SAMD9L

91

Q8IVG5
EKQQSSKSGHKKQKN

NRXN3

616

Q9HDB5
KKQHSQHAKQSSKPV

SECISBP2

461

Q96T21
RQKHAKNNSQAKPSA

MUTYH

36

Q9UIF7
NKNSNKFKHRDVPTK

PHYHIP

46

Q92561
HLNKTAEAQPSENKK

SLCO1B1

6

Q9Y6L6
LPDSQQQHQSSKKGK

BRD2

331

P25440
QKKNTDKDHPNTGNK

ZNF292

2606

O60281
PKHKGKQKSRNNESE

TTC3

436

P53804
GKAFKQSSNLTNHKK

ZNF708

286

P17019
HSNEKKNTPAAQKNK

ZNF800

436

Q2TB10
QKLPQKNSSEGNKHH

PTPRC

1146

P08575
DPVNKVQNKLHSANK

TEX9

111

Q8N6V9
QSKNDHPTDKKGNRK

ZNF638

1796

Q14966
QKVLSKNLNPNSKHS

ZNF311

221

Q5JNZ3