Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium-dependent cysteine-type endopeptidase activity	CAPN9 CAPN1 CAPN8 CAPN5	2.43e-06	17	116	4	GO:0004198
GeneOntologyMolecularFunction	peptidase activity	CAPN9 PAPPA2 DPEP1 TMPRSS6 AMZ1 CAPN1 PSMB6 PRSS22 TMPRSS4 ST14 ADAMTS12 CAPN8 METAP1 ADAMTS9 CAPN5	5.88e-06	654	116	15	GO:0008233
GeneOntologyMolecularFunction	endopeptidase activity	CAPN9 PAPPA2 TMPRSS6 CAPN1 PSMB6 PRSS22 TMPRSS4 ST14 ADAMTS12 CAPN8 ADAMTS9 CAPN5	7.78e-06	430	116	12	GO:0004175
GeneOntologyMolecularFunction	axon guidance receptor activity	PTK7 EPHA7 EPHB1	5.24e-05	13	116	3	GO:0008046
GeneOntologyMolecularFunction	transmembrane-ephrin receptor activity	EPHA10 EPHA7 EPHB1	8.26e-05	15	116	3	GO:0005005
GeneOntologyMolecularFunction	metallopeptidase activity	PAPPA2 DPEP1 TMPRSS6 AMZ1 ADAMTS12 METAP1 ADAMTS9	1.69e-04	200	116	7	GO:0008237
GeneOntologyMolecularFunction	ephrin receptor activity	EPHA10 EPHA7 EPHB1	1.73e-04	19	116	3	GO:0005003
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	PTK7 EPHA10 EPHA7 EPHB1	5.57e-04	65	116	4	GO:0004714
GeneOntologyMolecularFunction	laminin binding	RPSA NTN4 THBS1	1.00e-03	34	116	3	GO:0043236
GeneOntologyBiologicalProcess	self proteolysis	TMPRSS6 CAPN1 CAPN8	7.13e-05	15	114	3	GO:0097264
GeneOntologyBiologicalProcess	detection of monosaccharide stimulus	REG3G REG3A	9.05e-05	3	114	2	GO:0034287
GeneOntologyBiologicalProcess	detection of hexose stimulus	REG3G REG3A	9.05e-05	3	114	2	GO:0009732
GeneOntologyBiologicalProcess	detection of carbohydrate stimulus	REG3G REG3A	9.05e-05	3	114	2	GO:0009730
GeneOntologyBiologicalProcess	positive regulation of detection of glucose	REG3G REG3A	9.05e-05	3	114	2	GO:2000972
GeneOntologyBiologicalProcess	regulation of detection of glucose	REG3G REG3A	9.05e-05	3	114	2	GO:2000970
GeneOntologyBiologicalProcess	detection of glucose	REG3G REG3A	9.05e-05	3	114	2	GO:0051594
Domain	calpain_III	CAPN9 CAPN1 CAPN8 CAPN5	7.21e-07	12	118	4	SM00720
Domain	C2_III	CAPN9 CAPN1 CAPN8 CAPN5	7.21e-07	12	118	4	IPR033883
Domain	Calpain_III	CAPN9 CAPN1 CAPN8 CAPN5	7.21e-07	12	118	4	IPR022683
Domain	Calpain_III	CAPN9 CAPN1 CAPN8 CAPN5	1.04e-06	13	118	4	PF01067
Domain	Calpain_domain_III	CAPN9 CAPN1 CAPN8 CAPN5	1.04e-06	13	118	4	IPR022682
Domain	Calpain_cysteine_protease	CAPN9 CAPN1 CAPN8 CAPN5	1.44e-06	14	118	4	IPR022684
Domain	Peptidase_C2	CAPN9 CAPN1 CAPN8 CAPN5	1.96e-06	15	118	4	PF00648
Domain	CysPc	CAPN9 CAPN1 CAPN8 CAPN5	1.96e-06	15	118	4	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN9 CAPN1 CAPN8 CAPN5	1.96e-06	15	118	4	IPR001300
Domain	CALPAIN_CAT	CAPN9 CAPN1 CAPN8 CAPN5	1.96e-06	15	118	4	PS50203
Domain	TSP_1	ADGRB1 ADGRB2 ISM2 ADAMTS12 THBS1 ADAMTS9	2.83e-06	63	118	6	PF00090
Domain	TSP1	ADGRB1 ADGRB2 ISM2 ADAMTS12 THBS1 ADAMTS9	3.41e-06	65	118	6	SM00209
Domain	TSP1_rpt	ADGRB1 ADGRB2 ISM2 ADAMTS12 THBS1 ADAMTS9	3.41e-06	65	118	6	IPR000884
Domain	TSP1	ADGRB1 ADGRB2 ISM2 ADAMTS12 THBS1 ADAMTS9	3.41e-06	65	118	6	PS50092
Domain	THIOL_PROTEASE_CYS	CAPN9 CAPN1 CAPN8 CAPN5	2.03e-05	26	118	4	PS00139
Domain	THIOL_PROTEASE_ASN	CAPN9 CAPN1 CAPN8 CAPN5	2.37e-05	27	118	4	PS00640
Domain	THIOL_PROTEASE_HIS	CAPN9 CAPN1 CAPN8 CAPN5	2.37e-05	27	118	4	PS00639
Domain	Pept_cys_AS	CAPN9 CAPN1 CAPN8 CAPN5	2.76e-05	28	118	4	IPR000169
Domain	Galactose-bd-like	LAMA5 CUL9 NTN4 EPHA10 EPHA7 EPHB1	2.90e-05	94	118	6	IPR008979
Domain	ARM-rpt_dom	GPRASP1 ARMCX5 ARMCX6	3.91e-05	11	118	3	IPR006911
Domain	Arm_2	GPRASP1 ARMCX5 ARMCX6	3.91e-05	11	118	3	PF04826
Domain	RECEPTOR_TYR_KIN_V_2	EPHA10 EPHA7 EPHB1	8.51e-05	14	118	3	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHA10 EPHA7 EPHB1	8.51e-05	14	118	3	PS00790
Domain	Tyr_kinase_rcpt_V_CS	EPHA10 EPHA7 EPHB1	8.51e-05	14	118	3	IPR001426
Domain	EphA2_TM	EPHA10 EPHA7 EPHB1	8.51e-05	14	118	3	PF14575
Domain	Ephrin_rcpt_lig-bd_dom	EPHA10 EPHA7 EPHB1	8.51e-05	14	118	3	IPR001090
Domain	Eph_TM	EPHA10 EPHA7 EPHB1	8.51e-05	14	118	3	IPR027936
Domain	EPH_lbd	EPHA10 EPHA7 EPHB1	8.51e-05	14	118	3	SM00615
Domain	Ephrin_lbd	EPHA10 EPHA7 EPHB1	8.51e-05	14	118	3	PF01404
Domain	Tyr_kinase_ephrin_rcpt	EPHA10 EPHA7 EPHB1	8.51e-05	14	118	3	IPR016257
Domain	EPH_LBD	EPHA10 EPHA7 EPHB1	8.51e-05	14	118	3	PS51550
Domain	GPCR_2_brain_angio_inhib	ADGRB1 ADGRB2	1.18e-04	3	118	2	IPR008077
Domain	EGF-like_CS	MUC3B LAMA5 NTN4 THBS1 EPHA10 NOTCH4 EPHA7 EPHB1	2.54e-04	261	118	8	IPR013032
Domain	SEA	MUC3B TMPRSS6 ST14	3.47e-04	22	118	3	PF01390
Domain	PROTEIN_KINASE_TYR	PRAG1 PTK7 EPHA10 EPHA7 EPHB1	3.75e-04	97	118	5	PS00109
Domain	Tyr_kinase_AS	PRAG1 PTK7 EPHA10 EPHA7 EPHB1	3.75e-04	97	118	5	IPR008266
Domain	SEA	MUC3B TMPRSS6 ST14	3.97e-04	23	118	3	PS50024
Domain	SEA_dom	MUC3B TMPRSS6 ST14	3.97e-04	23	118	3	IPR000082
Domain	Ephrin_rec_like	EPHA10 EPHA7 EPHB1	5.11e-04	25	118	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHA10 EPHA7 EPHB1	5.11e-04	25	118	3	IPR011641
Domain	SH3_1	SH3PXD2B ARHGEF9 MAP3K10 SLA2 EPS8L3 SNX9	6.13e-04	164	118	6	PF00018
Domain	HRM	ADGRB1 ADGRB2 ADGRA2	7.18e-04	28	118	3	PF02793
Domain	Notch_dom	PAPPA2 NOTCH4	8.14e-04	7	118	2	IPR000800
Domain	Notch	PAPPA2 NOTCH4	8.14e-04	7	118	2	PF00066
Domain	NL	PAPPA2 NOTCH4	8.14e-04	7	118	2	SM00004
Domain	-	IGSF8 PAPPA2 SPEG IGSF5 ADGRA2 PTK7 CD19 NCR2 IL6R EPHA10 EPHA7 EPHB1	9.99e-04	663	118	12	2.60.40.10
Domain	Prot_kinase_dom	GAK SPEG SCYL1 PRAG1 MAP3K4 PTK7 MAP3K10 EPHA10 EPHA7 EPHB1	1.08e-03	489	118	10	IPR000719
Domain	FN3	PAPPA2 SPEG IL6R EPHA10 EPHA7 EPHB1	1.15e-03	185	118	6	SM00060
Domain	PROTEIN_KINASE_DOM	GAK SPEG SCYL1 PRAG1 MAP3K4 PTK7 MAP3K10 EPHA10 EPHA7 EPHB1	1.15e-03	493	118	10	PS50011
Domain	-	CUL9 EPHA10 EPHA7 EPHB1	1.18e-03	73	118	4	2.60.120.260
Domain	GPS	ADGRB1 ADGRB2 ADGRA2	1.28e-03	34	118	3	SM00303
Domain	Pkinase_Tyr	PTK7 MAP3K10 EPHA10 EPHA7 EPHB1	1.36e-03	129	118	5	PF07714
Domain	GPS	ADGRB1 ADGRB2 ADGRA2	1.39e-03	35	118	3	PF01825
Domain	EGF_2	MUC3B LAMA5 THBS1 EPHA10 NOTCH4 EPHA7 EPHB1	1.48e-03	265	118	7	PS01186
Domain	GPS	ADGRB1 ADGRB2 ADGRA2	1.51e-03	36	118	3	PS50221
Domain	GPS	ADGRB1 ADGRB2 ADGRA2	1.63e-03	37	118	3	IPR000203
Domain	C_TYPE_LECTIN_1	REG3G CLEC4M KLRK1 REG3A	1.65e-03	80	118	4	PS00615
Domain	Ig-like_fold	IGSF8 PAPPA2 SPEG IGSF5 ADGRA2 PTK7 CD19 NCR2 IL6R EPHA10 EPHA7 EPHB1	1.70e-03	706	118	12	IPR013783
Domain	Ser-Thr/Tyr_kinase_cat_dom	PTK7 MAP3K10 EPHA10 EPHA7 EPHB1	1.84e-03	138	118	5	IPR001245
Domain	Lectin_C	REG3G CLEC4M KLRK1 REG3A	1.98e-03	84	118	4	PF00059
Domain	CLECT	REG3G CLEC4M KLRK1 REG3A	1.98e-03	84	118	4	SM00034
Domain	GPCR_2_extracellular_dom	ADGRB1 ADGRB2 ADGRA2	2.05e-03	40	118	3	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	ADGRB1 ADGRB2 ADGRA2	2.05e-03	40	118	3	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRB1 ADGRB2 ADGRA2	2.05e-03	40	118	3	PS50227
Domain	C_TYPE_LECTIN_2	REG3G CLEC4M KLRK1 REG3A	2.07e-03	85	118	4	PS50041
Domain	GAIN_dom_N	ADGRB1 ADGRB2	2.10e-03	11	118	2	IPR032471
Domain	GAIN	ADGRB1 ADGRB2	2.10e-03	11	118	2	PF16489
Domain	FN3_dom	PAPPA2 SPEG IL6R EPHA10 EPHA7 EPHB1	2.13e-03	209	118	6	IPR003961
Domain	C-type_lectin-like	REG3G CLEC4M KLRK1 REG3A	2.16e-03	86	118	4	IPR001304
Domain	Kinase-like_dom	GAK SPEG SCYL1 PRAG1 MAP3K4 PTK7 MAP3K10 EPHA10 EPHA7 EPHB1	2.31e-03	542	118	10	IPR011009
Domain	Tyr_kinase_cat_dom	PTK7 EPHA10 EPHA7 EPHB1	2.35e-03	88	118	4	IPR020635
Domain	TyrKc	PTK7 EPHA10 EPHA7 EPHB1	2.35e-03	88	118	4	SM00219
Domain	SH3	SH3PXD2B ARHGEF9 MAP3K10 SLA2 EPS8L3 SNX9	2.51e-03	216	118	6	SM00326
Domain	SH3	SH3PXD2B ARHGEF9 MAP3K10 SLA2 EPS8L3 SNX9	2.51e-03	216	118	6	PS50002
Domain	C-type_lectin_CS	REG3G CLEC4M REG3A	2.52e-03	43	118	3	IPR018378
Domain	TRYPSIN_SER	TMPRSS6 PRSS22 TMPRSS4 ST14	2.55e-03	90	118	4	IPR033116
Domain	SH3_domain	SH3PXD2B ARHGEF9 MAP3K10 SLA2 EPS8L3 SNX9	2.75e-03	220	118	6	IPR001452
Domain	Ldl_recept_a	TMPRSS6 TMPRSS4 ST14	2.88e-03	45	118	3	PF00057
Domain	-	TMPRSS6 TMPRSS4 ST14	3.06e-03	46	118	3	4.10.400.10
Domain	Growth_fac_rcpt_	LAMA5 NTN4 NOTCH4 EPHA7 EPHB1	3.13e-03	156	118	5	IPR009030
Domain	LDLRA_1	TMPRSS6 TMPRSS4 ST14	3.46e-03	48	118	3	PS01209
Domain	ZINC_PROTEASE	PAPPA2 AMZ1 ADAMTS12 ADAMTS9	3.46e-03	98	118	4	PS00142
Domain	C-type_lectin-like/link	REG3G CLEC4M KLRK1 REG3A	3.59e-03	99	118	4	IPR016186
Domain	LDrepeatLR_classA_rpt	TMPRSS6 TMPRSS4 ST14	3.67e-03	49	118	3	IPR002172
Domain	LDLa	TMPRSS6 TMPRSS4 ST14	3.67e-03	49	118	3	SM00192
Domain	LDLRA_2	TMPRSS6 TMPRSS4 ST14	3.67e-03	49	118	3	PS50068
Domain	fn3	SPEG IL6R EPHA10 EPHA7 EPHB1	3.68e-03	162	118	5	PF00041
Domain	7tm_2	ADGRB1 ADGRB2 ADGRA2	3.88e-03	50	118	3	PF00002
Domain	G_PROTEIN_RECEP_F2_2	ADGRB1 ADGRB2 ADGRA2	3.88e-03	50	118	3	PS00650
Domain	TRYPSIN_HIS	TMPRSS6 PRSS22 TMPRSS4 ST14	4.14e-03	103	118	4	IPR018114
Domain	Laminin_N	LAMA5 NTN4	4.48e-03	16	118	2	IPR008211
Domain	LamNT	LAMA5 NTN4	4.48e-03	16	118	2	SM00136
Domain	LAMININ_NTER	LAMA5 NTN4	4.48e-03	16	118	2	PS51117
Domain	Laminin_N	LAMA5 NTN4	4.48e-03	16	118	2	PF00055
Domain	TRYPSIN_SER	TMPRSS6 PRSS22 TMPRSS4 ST14	4.58e-03	106	118	4	PS00135
Domain	CTDL_fold	REG3G CLEC4M KLRK1 REG3A	4.74e-03	107	118	4	IPR016187
Domain	TRYPSIN_HIS	TMPRSS6 PRSS22 TMPRSS4 ST14	4.74e-03	107	118	4	PS00134
Domain	IG	IGSF8 SPEG IGSF5 ADGRA2 PTK7 CD19 NCR2 IL6R	5.29e-03	421	118	8	SM00409
Domain	Ig_sub	IGSF8 SPEG IGSF5 ADGRA2 PTK7 CD19 NCR2 IL6R	5.29e-03	421	118	8	IPR003599
Domain	Peptidase_S1A	TMPRSS6 PRSS22 TMPRSS4 ST14	5.75e-03	113	118	4	IPR001314
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	CAPN9 TMPRSS6 CAPN1 LAMA5 CAPN8 ADAMTS9 CAPN5	1.68e-05	140	82	7	M587
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	CAPN9 TMPRSS6 CAPN1 LAMA5 CAPN8 NTN4 THBS1 ADAMTS9 CAPN5	5.96e-05	300	82	9	M610
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SPEG KAT6A ADGRB2 APBB3 LAMA5 CUL9 RPSA MED13L PRAG1 ADGRA2 ST14 SH3PXD2B SLC2A4RG MTMR3 ZNF324B CEP170B SOWAHB DYNC1H1	4.86e-08	1105	120	18	35748872
Pubmed	The calpain family and human disease.	CAPN9 CAPN1 CAPN8	1.60e-07	4	120	3	11516996
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADGRB1 ADGRB2 ISM2 ADAMTS12 THBS1 ADAMTS9	2.47e-07	75	120	6	20637190
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	MED13L THBS1 RASGRP3 MTMR3 PBXIP1	4.88e-06	71	120	5	33541421
Pubmed	Phenotypic analysis of mice lacking the Tmprss2-encoded protease.	TMPRSS6 TMPRSS4 ST14	8.61e-06	12	120	3	16428450
Pubmed	EPHA7 and EPHA10 Physically Interact and Differentially Co-localize in Normal Breast and Breast Carcinoma Cell Lines, and the Co-localization Pattern Is Altered in EPHB6-expressing MDA-MB-231 Cells.	EPHA10 EPHA7	1.18e-05	2	120	2	27566654
Pubmed	Regulation of pancreatitis-associated protein (HIP/PAP) mRNA levels in mouse pancreas and small intestine.	REG3G REG3A	1.18e-05	2	120	2	8795446
Pubmed	Pancreatic islet immunoreactivity to the Reg protein INGAP.	REG3G REG3A	1.18e-05	2	120	2	17998566
Pubmed	Human NK cytotoxicity against porcine cells is triggered by NKp44 and NKG2D.	KLRK1 NCR2	1.18e-05	2	120	2	16210654
Pubmed	Regenerating islet-derived 3-alpha is a biomarker of gastrointestinal graft-versus-host disease.	REG3G REG3A	1.18e-05	2	120	2	21979939
Pubmed	HIP/PAP protects against bleomycin-induced lung injury and inflammation and subsequent fibrosis in mice.	REG3G REG3A	1.18e-05	2	120	2	32352211
Pubmed	The crystal structures of human calpains 1 and 9 imply diverse mechanisms of action and auto-inhibition.	CAPN9 CAPN1	1.18e-05	2	120	2	17157313
Pubmed	Reg3β is associated with cardiac inflammation and provides prognostic information in patients with acute coronary syndrome.	REG3G REG3A	1.18e-05	2	120	2	29544958
Pubmed	Targeted expression of islet neogenesis associated protein to beta cells enhances glucose tolerance and confers resistance to streptozotocin-induced hyperglycemia.	REG3G REG3A	1.18e-05	2	120	2	21187123
Pubmed	Regulation of C-type lectin antimicrobial activity by a flexible N-terminal prosegment.	REG3G REG3A	1.18e-05	2	120	2	19095652
Pubmed	Symbiotic bacteria direct expression of an intestinal bactericidal lectin.	REG3G REG3A	1.18e-05	2	120	2	16931762
Pubmed	Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation.	REG3G REG3A	1.18e-05	2	120	2	26867181
Pubmed	Salmonella-induced mucosal lectin RegIIIβ kills competing gut microbiota.	REG3G REG3A	1.18e-05	2	120	2	21694778
Pubmed	Recombinant Reg3α protein protects against experimental acute pancreatitis in mice.	REG3G REG3A	1.18e-05	2	120	2	26683606
Pubmed	Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense.	CAPN9 CAPN8	1.18e-05	2	120	2	20686710
Pubmed	Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP).	REG3G REG3A	1.18e-05	2	120	2	7679928
Pubmed	Intestinal microbiota transplantation reveals the role of microbiota in dietary regulation of RegIIIβ and RegIIIγ expression in mouse intestine.	REG3G REG3A	1.18e-05	2	120	2	32560820
Pubmed	Structural organization and chromosomal localization of a human gene (HIP/PAP) encoding a C-type lectin overexpressed in primary liver cancer.	REG3G REG3A	1.18e-05	2	120	2	8076648
Pubmed	A Gastrointestinal Calpain Complex, G-calpain, Is a Heterodimer of CAPN8 and CAPN9 Calpain Isoforms, Which Play Catalytic and Regulatory Roles, Respectively.	CAPN9 CAPN8	1.18e-05	2	120	2	27881674
Pubmed	The Reg3α (HIP/PAP) Lectin Suppresses Extracellular Oxidative Stress in a Murine Model of Acute Liver Failure.	REG3G REG3A	1.18e-05	2	120	2	25938566
Pubmed	Molecular cloning and tissue-specific expression of a new member of the regenerating protein family, islet neogenesis-associated protein-related protein.	REG3G REG3A	1.18e-05	2	120	2	10564727
Pubmed	Pancreatic islet-specific overexpression of Reg3β protein induced the expression of pro-islet genes and protected the mice against streptozotocin-induced diabetes mellitus.	REG3G REG3A	1.18e-05	2	120	2	21245462
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SPEG TNRC6B CUL9 MED13L MAP3K4 ARHGEF9 MTMR3 CEP170B DYNC1H1	1.26e-05	407	120	9	12693553
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	IGSF8 MAN1A1 MAGED1 PSMB6 SCYL1 CMSS1 ECPAS PTK7 CNNM3 MOGS USO1 SNX9 DYNC1H1	2.36e-05	942	120	13	31073040
Pubmed	Pancreatic STAT3 protects mice against caerulein-induced pancreatitis via PAP1 induction.	REG3G REG3A	3.53e-05	3	120	2	23064197
Pubmed	p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I.	REG3G REG3A	3.53e-05	3	120	2	14660681
Pubmed	Exploring the link between germline and somatic genetic alterations in breast carcinogenesis.	EPHA7 EPHB1	3.53e-05	3	120	2	21124932
Pubmed	The protein phosphatase-1 targeting subunit TIMAP regulates LAMR1 phosphorylation.	RPSA PPP1CA	3.53e-05	3	120	2	16263087
Pubmed	Scyl1 regulates Golgi morphology.	SCYL1 USO1	3.53e-05	3	120	2	20209057
Pubmed	Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease.	REG3G REG3A	3.53e-05	3	120	2	30106382
Pubmed	HIP/PAP gene, encoding a C-type lectin overexpressed in primary liver cancer, is expressed in nervous system as well as in intestine and pancreas of the postimplantation mouse embryo.	REG3G REG3A	3.53e-05	3	120	2	10329612
Pubmed	Myocardial Accumulations of Reg3A, Reg3γ and Oncostatin M Are Associated with the Formation of Granulomata in Patients with Cardiac Sarcoidosis.	REG3G REG3A	3.53e-05	3	120	2	33923774
Pubmed	Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1).	ADGRB1 ADGRB2	3.53e-05	3	120	2	9533023
Pubmed	Expression of brain-specific angiogenesis inhibitor 3 (BAI3) in normal brain and implications for BAI3 in ischemia-induced brain angiogenesis and malignant glioma.	ADGRB1 ADGRB2	3.53e-05	3	120	2	15225653
Pubmed	Deletion of genes encoding PU.1 and Spi-B in B cells impairs differentiation and induces pre-B cell acute lymphoblastic leukemia.	SPIB CD19	3.53e-05	3	120	2	21768304
Pubmed	Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2, and mCAP3) and serum- and glucocorticoid-regulated kinase (Sgk1) in Xenopus Oocytes.	TMPRSS4 ST14	3.53e-05	3	120	2	12149280
Pubmed	The TGFβ-induced phosphorylation and activation of p38 mitogen-activated protein kinase is mediated by MAP3K4 and MAP3K10 but not TAK1.	MAP3K4 MAP3K10	3.53e-05	3	120	2	23760366
Pubmed	Increased expression of P2RY2, CD248 and EphB1 in gastric cancers from Chilean patients.	P2RY2 EPHB1	3.53e-05	3	120	2	24716914
Pubmed	Myocardial healing requires Reg3β-dependent accumulation of macrophages in the ischemic heart.	REG3G REG3A	3.53e-05	3	120	2	25751817
Pubmed	REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway.	REG3G REG3A	3.53e-05	3	120	2	34099862
Pubmed	IL-22-induced antimicrobial peptides are key determinants of mucosal vaccine-induced protection against H. pylori in mice.	REG3G REG3A	3.53e-05	3	120	2	27143303
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GPRASP1 DLGAP1 MAGED1 APBB3 CUL9 MED13L ZNF785 METAP1 THBS1 ADAMTS9 MTMR3 MAP3K10 CERCAM PBXIP1 DYNC1H1	3.77e-05	1285	120	15	35914814
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	GPRASP1 DLGAP1 MAGED1 ACACB PSMB6 ADGRB1 ADGRB2 TNRC6B RPSA PTK7 PPP1CA MAP3K10 ENO1 CEP170B	4.01e-05	1139	120	14	36417873
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	DLGAP1 ADGRB2 GRM3 PRAG1 PPP1CA CEP170B DYNC1H1	5.70e-05	281	120	7	28706196
Pubmed	Transcriptional activation of Reg2 and Reg3β genes by glucocorticoids and interleukin-6 in pancreatic acinar and islet cells.	REG3G REG3A	7.05e-05	4	120	2	23147030
Pubmed	Intestinally secreted C-type lectin Reg3b attenuates salmonellosis but not listeriosis in mice.	REG3G REG3A	7.05e-05	4	120	2	22252863
Pubmed	Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1.	TMPRSS4 ST14	7.05e-05	4	120	2	16524950
Pubmed	The antimicrobial protein REG3A regulates keratinocyte proliferation and differentiation after skin injury.	REG3G REG3A	7.05e-05	4	120	2	22727489
Pubmed	Coordinated age-dependent and pancreatic-specific expression of mouse Reg2Reg3α, and Reg3β genes.	REG3G REG3A	7.05e-05	4	120	2	21410322
Pubmed	Overexpression of Reg3alpha increases cell growth and the levels of cyclin D1 and CDK4 in insulinoma cells.	REG3G REG3A	7.05e-05	4	120	2	19343564
Pubmed	Regulation of B cell linker protein transcription by PU.1 and Spi-B in murine B cell acute lymphoblastic leukemia.	SPIB CD19	7.05e-05	4	120	2	22956576
Pubmed	Calpain: novel family members, activation, and physiologic function.	CAPN9 CAPN1	7.05e-05	4	120	2	8561910
Pubmed	IL17 Functions through the Novel REG3β-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer.	REG3G REG3A	7.05e-05	4	120	2	26404002
Pubmed	Reg3β deficiency impairs pancreatic tumor growth by skewing macrophage polarization.	REG3G REG3A	7.05e-05	4	120	2	23867474
Pubmed	Mucin Muc2 deficiency and weaning influences the expression of the innate defense genes Reg3β, Reg3γ and angiogenin-4.	REG3G REG3A	7.05e-05	4	120	2	22723890
Pubmed	The gut peptide Reg3g links the small intestine microbiome to the regulation of energy balance, glucose levels, and gut function.	REG3G REG3A	7.05e-05	4	120	2	36240758
Pubmed	Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias.	KLRK1 NCR2	7.05e-05	4	120	2	15657183
Pubmed	The pancreas responds to remote damage and systemic stress by secretion of the pancreatic secretory proteins PSP/regI and PAP/regIII.	REG3G REG3A	7.05e-05	4	120	2	28415799
Pubmed	Identification of a novel Reg family gene, Reg IIIdelta, and mapping of all three types of Reg family gene in a 75 kilobase mouse genomic region.	REG3G REG3A	7.05e-05	4	120	2	10767532
Pubmed	Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events.	GPRASP1 ARMCX5 ARMCX6	7.69e-05	24	120	3	16221301
Pubmed	Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.	ADGRA2 PTK7 CNNM3 DYNC1H1	8.73e-05	67	120	4	21875946
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	LAMA5 CUL9 ADGRA2 THBS1 ENO1 EPHB1	1.03e-04	214	120	6	22199357
Pubmed	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	IGSF8 CAPN1 LAMA5 THBS1 MOGS TOR3A ENO1 DYNC1H1	1.04e-04	417	120	8	19199708
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	ACACB SCYL1 ARMCX5 PPM1K PTK7 PPP1CA MTMR3 EPHA7	1.10e-04	420	120	8	28065597
Pubmed	Marginal zone B cells regulate antigen capture by marginal zone macrophages.	CLEC4M CD19	1.17e-04	5	120	2	21257969
Pubmed	Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis.	TMPRSS6 ST14	1.17e-04	5	120	2	28490634
Pubmed	IL-36γ Induced by the TLR3-SLUG-VDR Axis Promotes Wound Healing via REG3A.	REG3G REG3A	1.17e-04	5	120	2	28774595
Pubmed	PU.1 opposes IL-7-dependent proliferation of developing B cells with involvement of the direct target gene bruton tyrosine kinase.	SPIB CD19	1.17e-04	5	120	2	25505273
Pubmed	The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development.	CD19 IL6R	1.17e-04	5	120	2	26329582
Pubmed	Deletion of the mouse RegIIIbeta (Reg2) gene disrupts ciliary neurotrophic factor signaling and delays myelination of mouse cranial motor neurons.	REG3G REG3A	1.17e-04	5	120	2	18678917
Pubmed	Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains.	CAPN1 CAPN8	1.17e-04	5	120	2	17646163
Pubmed	Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus.	CAPN1 CAPN5	1.17e-04	5	120	2	14981075
Pubmed	Structure, chromosomal localization and expression of mouse genes encoding type III Reg, RegIII alpha, RegIII beta, RegIII gamma.	REG3G REG3A	1.17e-04	5	120	2	9055810
Pubmed	Changes in gut microbiome correlate with intestinal barrier dysfunction and inflammation following a 3-day ethanol exposure in aged mice.	REG3G REG3A	1.17e-04	5	120	2	36150609
Pubmed	CD5 Binds to Interleukin-6 and Induces a Feed-Forward Loop with the Transcription Factor STAT3 in B Cells to Promote Cancer.	CD19 IL6R	1.17e-04	5	120	2	27096320
Pubmed	A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice.	GPRASP1 ARMCX5 ARMCX6	1.23e-04	28	120	3	23677977
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PRUNE2 MAGED1 TMEM61 ACACB SCYL1 APOBR SLA2 DYNC1H1	1.29e-04	430	120	8	35044719
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRB1 ADGRB2 ADGRA2	1.37e-04	29	120	3	15203201
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	KAT6A ST14 CAPN8 THBS1 SH3PXD2B TOR3A DYNC1H1	1.60e-04	332	120	7	37433992
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	MAGED1 ACACB KRI1 TNRC6B ECPAS PPP1CA MTMR3 CEP170B	1.65e-04	446	120	8	24255178
Pubmed	Reg proteins direct accumulation of functionally distinct macrophage subsets after myocardial infarction.	REG3G REG3A	1.75e-04	6	120	2	29850784
Pubmed	Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival.	LAMA5 CD19	1.75e-04	6	120	2	23847204
Pubmed	A novel upregulation of glutathione peroxidase 1 by knockout of liver-regenerating protein Reg3β aggravates acetaminophen-induced hepatic protein nitration.	REG3G REG3A	1.75e-04	6	120	2	23811004
Pubmed	Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.	KLRK1 NCR2	1.75e-04	6	120	2	24673109
Pubmed	The Reg family member INGAP is a marker of endocrine patterning in the embryonic pancreas.	REG3G REG3A	1.75e-04	6	120	2	18192873
Pubmed	A Role for Sensory end Organ-Derived Signals in Regulating Muscle Spindle Proprioceptor Phenotype.	REG3G GRM3 REG3A	1.85e-04	32	120	3	30926747
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRB1 ADGRB2 ADGRA2	2.03e-04	33	120	3	25713288
Pubmed	Defining the membrane proteome of NK cells.	IGSF8 GAK MAN1A1 SCYL1 RPSA ECPAS APOBR TUBGCP6 CNNM3 MOGS USO1 ENO1 DYNC1H1	2.04e-04	1168	120	13	19946888
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	DPEP1 MAN1A1 CAPN1 PSMB6 LAMA5 SERINC2 SLC22A12 THBS1 MOGS CAPN5 SNX9 DYNC1H1	2.12e-04	1016	120	12	19056867
Pubmed	Inceptor counteracts insulin signalling in β-cells to control glycaemia.	ACACB REG3G REG3A	2.22e-04	34	120	3	33505018
Pubmed	BMI1 and MEL18 Promote Colitis-Associated Cancer in Mice via REG3B and STAT3.	REG3G REG3A	2.45e-04	7	120	2	28780076
Pubmed	Structure and physiological function of calpains.	CAPN1 CAPN5	2.45e-04	7	120	2	9396712
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	PAPPA2 LAMA5 TNRC6B PRAMEF12 ADAMTS9 RASGRP3 EPHA7	2.76e-04	363	120	7	14691545
Pubmed	Immune surveillance and therapy of lymphomas driven by Epstein-Barr virus protein LMP1 in a mouse model.	KLRK1 CD19	3.26e-04	8	120	2	22341446
Pubmed	Altered gene expression for calpain/calpastatin system in motor neuron degeneration (Mnd) mutant mouse brain and spinal cord.	CAPN1 CAPN5	3.26e-04	8	120	2	9473662
Interaction	CRELD2 interactions	IGSF5 TMPRSS4 ST14 WNT10A TOR3A EPHA10	4.38e-06	73	118	6	int:CRELD2
Cytoband	19q13.43	ZNF497 ZNF324 ZNF324B NLRP13	8.36e-05	87	120	4	19q13.43
Cytoband	Ensembl 112 genes in cytogenetic band chrXq22	GPRASP1 ARMCX5 ARMCX6 FAM199X	1.11e-03	172	120	4	chrXq22
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	SPIB COX6B1 ETV2 LENG9 ITPKC ZNF497 MAP3K10 ZNF324 ZNF324B NLRP13	1.18e-03	1192	120	10	chr19q13
Cytoband	2q35	SPEG WNT10A RESP18	1.19e-03	79	120	3	2q35
Cytoband	Ensembl 112 genes in cytogenetic band chr11q13	CAPN1 SCYL1 SLC22A12 PPP1CA P2RY2 CAPN5	1.28e-03	454	120	6	chr11q13
GeneFamily	C2 domain containing\|Calpains	CAPN9 CAPN1 CAPN8 CAPN5	5.42e-07	15	83	4	975
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHA10 EPHA7 EPHB1	3.27e-05	14	83	3	1095
GeneFamily	Adhesion G protein-coupled receptors, subfamily B	ADGRB1 ADGRB2	6.23e-05	3	83	2	912
GeneFamily	Proteases, serine	TMPRSS6 PRSS22 TMPRSS4 ST14	2.00e-04	63	83	4	738
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	REG3G KLRK1 REG3A	8.77e-04	41	83	3	1298
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	GPRASP1 ARMCX5 ARMCX6	1.01e-03	43	83	3	409
GeneFamily	Immunoglobulin like domain containing	IGSF5 ADGRA2 PTK7 CD19 IL6R	1.95e-03	193	83	5	594
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS12 ADAMTS9	3.38e-03	19	83	2	50
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K4 MAP3K10	5.38e-03	24	83	2	654
ToppCell	390C-Myeloid-Dendritic-pDC\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MAGED1 SPIB PPM1K PTK7 SLA2 NOTCH4 EPHB1	4.13e-07	172	119	7	3f894c74916d49a995b2d4651ca1c6733c14ce9c
ToppCell	myeloid-Dendritic_cell-Plasmacytoid_dendritic_cell\|myeloid / Lineage, cell class and subclass	SPIB PPM1K PTK7 WNT10A SLA2 NOTCH4 EPHB1	5.20e-07	178	119	7	f75591988bbbeba073b66329a3437cb9b02f7648
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPEP1 SPIB APOBR ST14 CLCN1 P2RY2 EPS8L3	5.82e-07	181	119	7	1d3d1b5a6efe9cedd03b7e0b5684df97f0246729
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPEP1 SPIB APOBR ST14 CLCN1 P2RY2 EPS8L3	5.82e-07	181	119	7	0069e8308de932df43660bbe926637c57b8bf7f6
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 TMPRSS6 IGSF5 TMPRSS4 SERINC2 ST14 RESP18	6.26e-07	183	119	7	4de2082dca2569d3aac3c9b466f27971c82d302b
ToppCell	droplet-Heart-4Chambers-21m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 TMPRSS6 IGSF5 TMPRSS4 SERINC2 ST14 RESP18	6.26e-07	183	119	7	a046b569bc10083d471b420eb2c6fee93437602d
ToppCell	normal_Lung-T/NK_cells-Treg\|T/NK_cells / Location, Cell class and cell subclass	TMPRSS6 CUL9 WNT10A SNX9 ENO1 PBXIP1 IL6R	6.74e-07	185	119	7	ea416362d3f06b4a0a7f08c2e5dbbc864f121555
ToppCell	ICU-NoSEP-Myeloid-pDC\|ICU-NoSEP / Disease, Lineage and Cell Type	SPIB PPM1K ST14 PTK7 WNT10A NOTCH4 EPHB1	6.74e-07	185	119	7	7564a47df4a4e3af30d40aa0f48bd9d9c82358ae
ToppCell	(0)_Myeloid-(01)_Dendritic_cell-(011)_pDC\|(01)_Dendritic_cell / immune cells in Peripheral Blood (logTPM normalization)	SPIB PPM1K PTK7 SLC2A4RG SNX9 NOTCH4 EPHB1	7.24e-07	187	119	7	068502efa3f0ac4cea2fa4a18d1c2f686a4fba54
ToppCell	(0)_Myeloid-(011)_pDC\|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)	SPIB PPM1K PTK7 WNT10A SLA2 NOTCH4 EPHB1	7.51e-07	188	119	7	a81b5d840490d6a636fe168f8cff2c4984369f09
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 REG3G TMPRSS4 SERINC2 PRAG1 ST14 CAPN8	8.35e-07	191	119	7	b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCell	Control-pDC\|Control / Disease condition and Cell class	SPIB PPM1K PTK7 WNT10A SLA2 NOTCH4 EPHB1	8.35e-07	191	119	7	543e1437a52d04436862dd1c27b4fae95c44fcc8
ToppCell	Control-pDC-\|Control / Disease condition and Cell class	SPIB PPM1K PTK7 WNT10A SLA2 NOTCH4 EPHB1	8.35e-07	191	119	7	1d7b0fae4d114d6db933c18b4eb2066ffa61356d
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1A1 MAGED1 PTK7 SH3PXD2B CERCAM PBXIP1 EPHA7	8.64e-07	192	119	7	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	droplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS22 LAMA5 SERINC2 PRAG1 ST14 CAPN8 CAPN5	9.27e-07	194	119	7	715e02e5f3250b1bfdc26b7dfd656ba4e705ea84
ToppCell	droplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS22 LAMA5 SERINC2 ST14 CAPN5 CEP170B SOWAHB	9.92e-07	196	119	7	9554ac6eb5f381bcde3ba40c32aa3fc340974540
ToppCell	Sepsis-ICU-NoSEP-Myeloid-pDC\|ICU-NoSEP / Disease, condition lineage and cell class	SPIB PPM1K ST14 PTK7 WNT10A SNX9 NOTCH4	1.10e-06	199	119	7	a199e67438eeed903d0996605591ec54400fdd66
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 PRSS22 TMPRSS4 SERINC2 PTK7 NTN4 THBS1	1.14e-06	200	119	7	ae91dc047dc80560ba298d8d21a772154fa2775d
ToppCell	droplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 SPIB CD19 WNT10A RESP18 EPHB1	6.72e-06	171	119	6	20ac3de9c164b409b70a30a8b6544ea491ef7c0e
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CAPN9 TMPRSS6 LAMA5 TMPRSS4 CAPN8 PBXIP1	6.94e-06	172	119	6	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	wk_15-18-Hematologic-Myeloid-pDC\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SPIB PPM1K ST14 WNT10A SLA2 EPHB1	7.18e-06	173	119	6	b571970e3ba88afc07041c5692ccfd85fc39e796
ToppCell	BAL-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPIB PHYHD1 PTK7 WNT10A SLA2 EPHB1	7.42e-06	174	119	6	ab654e87c7eab7f33adc61be7a86da5c4d88008d
ToppCell	BAL-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SPIB PHYHD1 PTK7 WNT10A SLA2 EPHB1	7.42e-06	174	119	6	d9bccff5258c4277bdd1edbd87e17c327ec125e8
ToppCell	BAL-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SPIB PHYHD1 PTK7 WNT10A SLA2 EPHB1	7.42e-06	174	119	6	2453419842fd22d066631615403393bfe4449bb8
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 FAXC SERINC2 ST14 RASGRP3 WNT10A	7.42e-06	174	119	6	cdfc50e5383c8670ce5109736aff36406f46c03d
ToppCell	normal_Lung-T/NK_cells-Treg\|normal_Lung / Location, Cell class and cell subclass	TMPRSS6 CUL9 RPSA WNT10A SNX9 PBXIP1	7.66e-06	175	119	6	bc846312e6a6d68b7ca661052fb4e02cfb8ed014
ToppCell	BAL-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPIB PHYHD1 PTK7 WNT10A SLA2 EPHB1	7.66e-06	175	119	6	6d5bdfbe53608e01c3845ecd908ca6d0fecc58f8
ToppCell	BAL-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPIB PHYHD1 PTK7 WNT10A SLA2 EPHB1	7.66e-06	175	119	6	6839ee3bb4457d13cb08ca8eb79ae33ddd256783
ToppCell	BAL-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPIB PHYHD1 PTK7 WNT10A SLA2 EPHB1	7.66e-06	175	119	6	9d6135e183179968555670abec39dff9da2c3219
ToppCell	Control-Lymphoid-pDC\|Control / Condition, Lineage and Cell class	SPIB ETV2 PHYHD1 PTK7 SLA2 EPHB1	7.92e-06	176	119	6	5de16ff65476bde8b23322a44e11412e14f1bafe
ToppCell	390C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	MAGED1 SPIB PTK7 SLA2 NOTCH4 EPHB1	7.92e-06	176	119	6	aab9603b7943b7f7243eb6190ebba998566196f3
ToppCell	Control-Myeloid-pDC\|Control / Disease group,lineage and cell class （2021.01.30）	SPIB PHYHD1 PTK7 WNT10A SLA2 EPHB1	7.92e-06	176	119	6	baa3563973ea1a351fe028f55828463d2a51bf1a
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_4\|Classical_Monocyte / Disease condition and Cell class	GAK APBB3 KLRK1 METAP1 SLA2 NOTCH4	8.72e-06	179	119	6	9d51318ac198a8801bd5c7031ebf2b0c74ffeeb6
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CAPN9 TMEM61 SERINC2 ST14 CAPN8 EPHA10	8.72e-06	179	119	6	c833ded1f9e87be2ba2037820d92a389560b711c
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_4\|COVID-19_Convalescent / Disease condition and Cell class	GAK APBB3 KLRK1 METAP1 SLA2 NOTCH4	8.72e-06	179	119	6	366e4a31db9e80fd1770ac9f1ae148fefeb9f7df
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CAPN9 PRSS22 IGSF5 TMPRSS4 CAPN5 EPS8L3	9.00e-06	180	119	6	3dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CAPN9 PRSS22 IGSF5 TMPRSS4 CAPN5 EPS8L3	9.00e-06	180	119	6	668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCell	facs-Heart-RA-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS22 REG3G TMPRSS4 SERINC2 THBS1 WNT10A	9.29e-06	181	119	6	c68d272eb41f81bd8ea4d0360733a2396bc87037
ToppCell	facs-Heart-RA-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS22 REG3G TMPRSS4 SERINC2 THBS1 WNT10A	9.29e-06	181	119	6	5e5eb89f224ee48065a328ade030cbc4dcdcac12
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 IGSF5 TMPRSS4 SERINC2 ST14 RESP18	9.29e-06	181	119	6	3fd16229a63de0971db5d48860c01173d7db518f
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN9 PRUNE2 ETV2 NTN4 TOR3A ACSS3	9.89e-06	183	119	6	5a936fb07074cec753bf19e3e3e52499605ea22c
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	CAPN9 TMPRSS4 SERINC2 CAPN8 CAPN5 EPS8L3	9.89e-06	183	119	6	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN9 PRUNE2 ETV2 NTN4 TOR3A ACSS3	9.89e-06	183	119	6	07c18ccc45ddc9c22e482bd9ffb87f46ebcfe473
ToppCell	(7)_DC_plasmacytoid\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	SPIB SERINC2 ST14 PTK7 NOTCH4 EPHB1	9.89e-06	183	119	6	2c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCell	IIF-Lymphocyte-B-B_naive\|IIF / Disease, Lineage and Cell Type	SPIB RPSA PPM1K CD19 RASGRP3 SNX9	1.05e-05	185	119	6	dec48908addfc71f32f5ce0ce73f2926e476f60b
ToppCell	healthy_donor-Lymphocytic-Dendritic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SPIB ST14 PTK7 WNT10A NOTCH4 EPHB1	1.08e-05	186	119	6	916f2aeea4989ba7a29e071e348a51010f010223
ToppCell	myeloid-Dendritic_cell-Plasmacytoid_dendritic_cell\|Dendritic_cell / Lineage, cell class and subclass	SPIB PPM1K PTK7 WNT10A NOTCH4 EPHB1	1.08e-05	186	119	6	858134580a09ed8a5eb6d6413d8ca9265904dfc1
ToppCell	control-Myeloid-pDC\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SPIB PPM1K WNT10A SLA2 NCR2 NOTCH4	1.08e-05	186	119	6	fccee4cfcc887358cf916d974f29627095b5ad9c
ToppCell	healthy_donor-Lymphocytic-Dendritic-pDC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SPIB ST14 PTK7 WNT10A NOTCH4 EPHB1	1.08e-05	186	119	6	45f66619e45d590c7365a51782d4ac46b7d31fde
ToppCell	severe_influenza-B_intermediate\|severe_influenza / disease group, cell group and cell class (v2)	SPIB PPM1K PRAG1 CD19 RASGRP3 SNX9	1.12e-05	187	119	6	d6db8595aa72fdabc4a056ba6ce09876868a66d5
ToppCell	COVID-19_Mild-pDC\|COVID-19_Mild / Disease condition and Cell class	SPIB PPM1K PTK7 WNT10A SLA2 EPHB1	1.15e-05	188	119	6	62d33d2990d4a2d32bd0863147e47f656df1966e
ToppCell	myeloid-pDC\|myeloid / Lineage and Cell class	SPIB PPM1K WNT10A SLA2 NOTCH4 EPHB1	1.15e-05	188	119	6	a2dc4bbeca2bdc00c51825dd65a699c54c72f241
ToppCell	COVID-19_Mild-pDC-\|COVID-19_Mild / Disease condition and Cell class	SPIB PPM1K PTK7 WNT10A SLA2 EPHB1	1.15e-05	188	119	6	a75c2cf2f8dae343c13aaa66b637658b935ed10a
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_activate-7\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPIB CCDC187 PPM1K CD19 RASGRP3 SNX9	1.19e-05	189	119	6	ef33cc03728a78423ee92d2ef1ffed4918d4221f
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-pDC\|lymph-node_spleen / Manually curated celltypes from each tissue	SPIB ARSI ST14 PTK7 NOTCH4 EPHB1	1.19e-05	189	119	6	6c2ace61a7d62bcf7e76b73e2da8b722d03e713b
ToppCell	Int-URO-Myeloid-pDC\|Int-URO / Disease, Lineage and Cell Type	SPIB PPM1K PTK7 WNT10A NOTCH4 EPHB1	1.19e-05	189	119	6	37aee7a0acd5fd5dd62f22608d72ff8afe210e5c
ToppCell	facs-Trachea-24m-Hematologic-lymphocytic\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPIB RPSA KLRK1 CD19 SLA2 ENO1	1.22e-05	190	119	6	10f7d33fd1ff096f8fe5b7b11a58819d6cc14fbc
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 ARSI PTK7 ADAMTS12 THBS1 ACSS3	1.22e-05	190	119	6	d60395739458d7f47a3350ade751fe3819500320
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	DLGAP1 TNRC6B MED13L PRAG1 PHIP ACSS3	1.30e-05	192	119	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 MAGED1 TMPRSS6 ADGRA2 SH3PXD2B CERCAM	1.34e-05	193	119	6	316ebdf15f75d88c348f909b643fcd315364ca84
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 MAGED1 TMPRSS6 ADGRA2 SH3PXD2B CERCAM	1.34e-05	193	119	6	1afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	DLGAP1 TNRC6B MED13L PRAG1 PHIP ACSS3	1.34e-05	193	119	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	droplet-Fat-Scat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 MAGED1 TMPRSS6 ADGRA2 SH3PXD2B CERCAM	1.34e-05	193	119	6	8dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CAPN9 PRUNE2 TMEM61 CAPN8 NTN4 CAPN5	1.38e-05	194	119	6	49cc5f5de4380302100e8cd937f08abe317ac75e
ToppCell	COPD-Epithelial-Goblet\|Epithelial / Disease state, Lineage and Cell class	PRSS22 TMPRSS4 SERINC2 ST14 SH3PXD2B SNX9	1.38e-05	194	119	6	72a2e0cba171ab59aa176e91a59a54c562af0390
ToppCell	severe_COVID-19-B_intermediate\|World / disease group, cell group and cell class (v2)	SPIB PPM1K CD19 RASGRP3 TOR3A SNX9	1.38e-05	194	119	6	cb346cb186fe80a8f490ae90b2539b3543ba0ca9
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-goblet\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CAPN9 PRUNE2 TMEM61 CAPN8 NTN4 CAPN5	1.38e-05	194	119	6	fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CAPN9 PRUNE2 TMEM61 ST14 CAPN8 CAPN5	1.42e-05	195	119	6	c5f33b420c9ac14dc67fea632b8c2bc2442cbf3d
ToppCell	droplet-Bladder-Unstain-18m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN1 LAMA5 RPSA SERINC2 THBS1 CAPN5	1.42e-05	195	119	6	2798776ed26a9db546c80f2a5c116c846108880c
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-Goblet_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CAPN9 PRUNE2 TMEM61 ST14 CAPN8 CAPN5	1.42e-05	195	119	6	219c5d0cde7f6082755154f54db221413ec555cb
ToppCell	NS-moderate-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAGED1 TMPRSS4 SERINC2 ST14 CAPN8 CAPN5	1.46e-05	196	119	6	70384c1da9baed843f414cfd1403ddd586a2db07
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-goblet\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CAPN9 PRUNE2 TMEM61 CAPN8 NTN4 CAPN5	1.46e-05	196	119	6	c2d17630f7bfc9e727de55e093c17fddac61b61f
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-goblet-Goblet_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CAPN9 PRUNE2 TMEM61 CAPN8 NTN4 CAPN5	1.46e-05	196	119	6	54c30023d04e7265373647f56fc93885804938b0
ToppCell	367C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SPEG LAMA5 MYRFL NTN4 ADAMTS9 CCDC107	1.46e-05	196	119	6	1d94cecd378a829dd8014fc086d7fca48c953a91
ToppCell	367C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SPEG LAMA5 MYRFL NTN4 ADAMTS9 CCDC107	1.46e-05	196	119	6	aacec48285bcb7ccf1b538187071885e3602cc49
ToppCell	severe-Plasmablast\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MAN1A1 MAGED1 USO1 RASGRP3 SLA2 TOR3A	1.55e-05	198	119	6	0b1620ad4352ee5d599a72931aaceab4ca407498
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPEG ADGRB2 LAMA5 ADGRA2 ADAMTS9 CCDC107	1.55e-05	198	119	6	7dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell	LPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_only / Treatment groups by lineage, cell group, cell type	ETV2 CUL9 PRAG1 MOGS EPHA7 EPHB1	1.55e-05	198	119	6	d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 SPIB SERINC2 APOBR ST14 EPS8L3	1.55e-05	198	119	6	a631be84e29c277216d89ec6265bd43e87c1dc86
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CAPN9 PRSS22 TMPRSS4 ST14 CAPN8 CAPN5	1.59e-05	199	119	6	e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCell	Control-Control-Myeloid-pDC\|Control / Disease, condition lineage and cell class	SPIB PPM1K ST14 PTK7 WNT10A NOTCH4	1.59e-05	199	119	6	8e9cac53fabe497ffa27fca0627eafe883af2534
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 PRSS22 TMPRSS4 PTK7 NTN4 WNT10A	1.59e-05	199	119	6	2e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCell	MS-IIF-Lymphocyte-B-B_naive\|IIF / Disease, condition lineage and cell class	SPIB RPSA PPM1K CD19 RASGRP3 SNX9	1.64e-05	200	119	6	15f429137b2a3906724118085fcd59750cd767c7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DPEP1 REG3G NTN4 THBS1 EPHA7	1.64e-05	200	119	6	105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCell	MS-IIF-Lymphocyte-B\|IIF / Disease, condition lineage and cell class	SPIB RPSA PPM1K CD19 RASGRP3 SNX9	1.64e-05	200	119	6	a0f3362b7ddfc122e30e75fb541bb0b7d0321c72
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHYHD1 PTK7 METTL24 CLCN1 EPHA7	3.48e-05	138	119	5	6b83c434895d82eaf3c222eef27acec76f9c0a77
ToppCell	Control-Plasmablast\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MAN1A1 LAMA5 ECPAS USO1 IL6R	4.41e-05	145	119	5	fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Fos_(Deep_layer_pyramidal_cells--layer_5_(IEG))\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TDRD5 ARSI CLCN1 CERCAM	5.42e-05	77	119	4	4879a1a72b950dadb78bc0312be75f1a32b935d5
ToppCell	Ionocyte\|World / shred by cell class for nasal brushing	TMEM61 ARSI THBS1 WNT10A TDRP	5.87e-05	154	119	5	6b78fb0c96fc7b5e901c39b3424f4aa8d0a6b9cf
ToppCell	Paneth_cell\|World / shred on cell type and cluster	PRUNE2 DLGAP1 MAN1A1 REG3G REG3A	7.04e-05	160	119	5	d787b7cdb8c3f677ac9c4934a5df9cc194df3987
ToppCell	C_07\|World / shred on cell type and cluster	PRUNE2 DLGAP1 MAN1A1 REG3G REG3A	7.04e-05	160	119	5	b7c5a8a1c85da92e1945721b6887b32fad7b76b8
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIB ADGRB1 CD19 WNT10A SNX9	7.46e-05	162	119	5	22f1abd20f43bc7e7fc46969da9962faf70ae5d2
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	APBB3 LAMA5 PHYHD1 PTK7 ACSS3	7.46e-05	162	119	5	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIB ADGRB1 CD19 WNT10A SNX9	7.46e-05	162	119	5	966df4558140c3d541999ab553f201ae76a1c401
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLGAP1 SPIB TMPRSS6 PRSS22 SOWAHB	7.46e-05	162	119	5	80619a93c57fe16daf91dc571874ef9ac888953d
ToppCell	facs-Marrow-KLS-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACACB IGSF5 KLRK1 RASGRP3 RESP18	7.91e-05	164	119	5	d2b5f51af7fcffddebe997ee302bacbd85d76852
ToppCell	Frontal_cortex\|World / BrainAtlas - Mouse McCarroll V32	PAPPA2 DLGAP1 PRSS22 WNT10A SOWAHB	7.91e-05	164	119	5	e09291711abf8680e78170328313719092b0142f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 PRAG1 NTN4 ADAMTS9 EPHA7	7.91e-05	164	119	5	382e42701779d12a7948690b3be72d06dd75c8b4
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 PHYHD1 PTK7 ZNF764 ACSS3	8.37e-05	166	119	5	89e2b8453180983533faccb4275867861876d7ee
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIB FAXC METTL24 CD19 WNT10A	8.86e-05	168	119	5	ce9fae8b295c668b0959d5007a8bcd401d80e258
Disease	sciatic neuropathy (biomarker_via_orthology)	CAPN1 REG3G RPSA REG3A IL6R	4.05e-05	99	113	5	DOID:11446 (biomarker_via_orthology)
Disease	hereditary spastic paraplegia 76 (implicated_via_orthology)	CAPN1 CAPN8	1.44e-04	5	113	2	DOID:0110821 (implicated_via_orthology)
Disease	acute pancreatitis (implicated_via_orthology)	REG3G REG3A	1.44e-04	5	113	2	DOID:2913 (implicated_via_orthology)
Disease	scoliosis (implicated_via_orthology)	PTK7 ADAMTS9	1.44e-04	5	113	2	DOID:0060249 (implicated_via_orthology)
Disease	dental caries, dentures	PRUNE2 P2RY2 MTMR3 WNT10A	1.54e-04	70	113	4	EFO_0003819, EFO_0010078
Disease	dentures	PRUNE2 P2RY2 MTMR3 WNT10A	1.54e-04	70	113	4	EFO_0010078
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CAPN9 CAPN1 CAPN8	3.56e-04	36	113	3	DOID:11723 (implicated_via_orthology)
Disease	Neurodevelopmental Disorders	DLGAP1 TNRC6B MED13L PTK7	4.58e-04	93	113	4	C1535926
Disease	hereditary spastic paraplegia (implicated_via_orthology)	CAPN9 CAPN1 CAPN8	6.04e-04	43	113	3	DOID:2476 (implicated_via_orthology)
Disease	pneumonia (implicated_via_orthology)	REG3G REG3A	6.41e-04	10	113	2	DOID:552 (implicated_via_orthology)
Disease	Gastric Adenocarcinoma	SPEG EPHA10 EPHB1	6.90e-04	45	113	3	C0278701
Disease	Metastatic melanoma	SCYL1 MAP3K10 EPHA7	1.18e-03	54	113	3	C0278883
Disease	puberty onset measurement	DLGAP1 ECPAS ZNF324 ZNF324B	1.38e-03	125	113	4	EFO_0005677
Disease	obesity (implicated_via_orthology)	CAPN9 MED13L CAPN8 ADAMTS9 NOTCH4	1.45e-03	215	113	5	DOID:9970 (implicated_via_orthology)
Disease	coronary thrombosis, GM11992	METTL24 NCR2	1.68e-03	16	113	2	EFO_0001124, EFO_1000883
Disease	Sjogren's syndrome (implicated_via_orthology)	ST14 THBS1	1.90e-03	17	113	2	DOID:12894 (implicated_via_orthology)
Disease	peritonsillar abscess	AMZ1 PRAG1	2.14e-03	18	113	2	EFO_0007429
Disease	skin sensitivity to sun	DPEP1 ADAMTS12	2.38e-03	19	113	2	EFO_0004795
Disease	lateral orbital frontal cortex volume measurement	NCR2 ACSS3	3.80e-03	24	113	2	EFO_0010312
Disease	response to antiviral drug, cirrhosis of liver	MAN1A1 FAXC	3.80e-03	24	113	2	EFO_0001422, EFO_0010123

Protein segments in the cluster

Peptide	Gene	Start	Entry
TWDDSWQPSGLVNGT	TDRD5	791	Q8NAT2
QTGDPAAEEWSPWSV	ADGRB2	306	O60241
AWLQTVSSDPEAQGW	PABPN1L	16	A6NDY0
VSSDPEAQGWGAWNE	PABPN1L	21	A6NDY0
LDGETLSWGPSWEQQ	CCDC187	916	A0A096LP49
WTQAVVGTWPSQEAG	AMZ1	321	Q400G9
AEPVAAWWSQEGPGE	ADGRA2	706	Q96PE1
QTGDPAAEEWSPWSV	ADGRB1	351	O14514
NGGAWGPWASDEEEE	ARSI	516	Q5FYB1
TWVASDGWGAQESII	GRM3	296	Q14832
GDEWWENQPTGAGSS	CMSS1	6	Q9BQ75
STSPGWWSSDDNLDG	DLGAP1	196	O14490
WGEREWNGPWSDTSE	CAPN5	286	O15484
NPWGEVEWSGAWSDD	CAPN8	286	A6NHC0
VEWSGAWSDDAPEWN	CAPN8	291	A6NHC0
SWWGEDDGSTLPDAQ	CEP170B	171	Q9Y4F5
NPWGEVEWTGAWSDS	CAPN1	296	P07384
TGEEPSVGSWFWPEE	ARMCX5	176	Q6P1M9
SVGSWFWPEEETSLQ	ARMCX5	181	Q6P1M9
ARPWTEDGDWTEPGA	ARMCX6	66	Q7L4S7
DILCPSDWTVGNWSE	ADAMTS12	941	P58397
WWGQIDDEEGWFPAS	ARHGEF9	46	O43307
GSPATWDNFGIWDNR	PPM1K	56	Q8N3J5
LWTETGTDGLWTDPH	ITPKC	136	Q96DU7
AWGPEAFTPDWESRE	PSMB6	16	P28072
PWSGSGLTVEWTEDD	ACACB	401	O00763
ELGWTANPASGWEEV	EPHB1	31	P54762
QSISFFGWWAGSEEP	FAXC	21	Q5TGI0
AVSGDEGWWTGQLPS	MAP3K10	51	Q02779
SWTVEGDINTDPWAG	METAP1	66	P53582
QDETWPDGWTAVTRD	METAP1	336	P53582
TDELVSEWFNQPWSG	MED13L	1476	Q71F56
IGDEAVSGPWSWDDI	MAGED1	696	Q9Y5V3
AWTSRFTIWDDPDAG	NCR2	76	O95944
VGGEDSTDSEWPWIV	PRSS22	51	Q9GZN4
WTEVWQENVPGSFGG	ECPAS	1506	Q5VYK3
WSDSEFEWQLPGSDI	FAM199X	131	Q6PEV8
GTTDNWDQGWLAPGD	ISM2	301	Q6H9L7
ETTEAEWGPAAWPED	LENG9	291	Q96B70
PTNGSWQWEDGSILS	KLRK1	161	P26718
GPAWTTSRADWTGDE	EPS8L3	366	Q8TE67
GPDWESDWIDTTISS	MYRFL	756	Q96LU7
GLEDDWNWDTWDGPE	KRI1	421	Q8N9T8
WWPNTPGDSVSEELG	TUBGCP6	1356	Q96RT7
AELGWTALPSNGWEE	EPHA10	46	Q5JZY3
PASNAIDGTERWWQS	LAMA5	116	O15230
EWISSPPNGWEEISG	EPHA7	46	Q15375
GPWNDTINGTWDGDE	P2RY2	6	P41231
GGDWSWRVTVEPQDS	MOGS	181	Q13724
WSDPDKDVQGWGEND	PPP1CA	206	P62136
KSSTSDWPTDNQDGW	KAT6A	446	Q92794
APQESWDEGDWTLSI	NBPF3	341	Q9H094
NFWGIWSGASALSPE	PRAMEF12	111	O95522
SVREDLAGAATWPWD	PAPPA2	691	Q9BXP8
EFGVAGWWEAAAPLS	RESP18	6	Q5W5W9
ASSSNPDLLGGWAAW	GAK	1026	O14976
GWAAWTETAASAVAP	GAK	1036	O14976
SIEDPFDQDDWGAWQ	ENO1	291	P06733
SGSTQWQRPTWELGD	APBB3	51	O95704
EMDVPVTDGSWGSWS	ADAMTS9	581	Q9P2N4
WWQTAVVDGSGSGNE	IGSF5	26	Q9NSI5
TAAEWIQDPDGSWAQ	IGSF8	271	Q969P0
AASWWVERPEDGELS	IGSF8	476	Q969P0
EEFGQGEWSEWSPEA	IL6R	296	P08887
GDSQAWEEPTNWSTE	CCDC107	221	Q8WV48
AWQPGWTVNVEGSGE	CD19	106	P15391
WACSEPSPWTQEGSG	FAM25E	56	A8MYX2
NWPWASGGSSILAEF	MAN1A1	336	P33908
DYEVSISGEWSPWQA	DYNC1H1	2536	Q14204
SDDDDLGWCNSWPST	HBP1	196	O60381
GATVLGTAFPSWDWN	CUL9	456	Q8IWT3
DSQALPWSGDWTDMA	ETV2	81	O00321
GDAEWLSDTETSSPW	CERCAM	541	Q5T4B2
GQVEWNGSWSDSSPE	CAPN9	281	O14815
NTPWADNWLVDTGDS	DPEP1	171	P16444
TSWSEADTEPCVDGW	SLC22A12	106	Q96S37
PTSWVTDWDEQRAEG	COX6B1	66	P14854
EASGTTWSPENWLQP	PHYHD1	266	Q5SRE7
GQPEVSWWGWRNADD	MTMR3	236	Q13615
QGSEPDGDGWEWSST	REG3G	111	Q6UW15
ETWDEEVVGTFSNWG	MUC3B	1186	Q9H195
DDSLGWGAPDWSTEA	MAP3K4	501	Q9Y6R4
RDSEDSWGTWEAQPV	MAP3K4	911	Q9Y6R4
PWAGSAQSLDEEAWR	METTL24	116	Q5JXM2
PAWATVGSWRDGQLD	GRIN3B	381	O60391
WFWEEEASPEAVAGV	GPRASP1	846	Q5JY77
PGTEEEEITVGSWFW	GPRASP1	866	Q5JY77
GSWFWPEEEASIQAG	GPRASP1	876	Q5JY77
WSAAPTAQATEWVGA	RPSA	276	P08865
PWFEVGDENSGWSAQ	USO1	261	O60763
QGTEPNGEGWEWSSS	REG3A	111	Q06141
VGSGNDPWSAWSASK	SNX9	101	Q9Y5X1
SGNWESSEGWGAQPE	SNX9	116	Q9Y5X1
GFSADSTEWWKASPQ	PRUNE2	1821	Q8WUY3
GEPLTIVSEDGDWWT	SLA2	56	Q9H6Q3
WEAEGSWEQGWQEPS	SCYL1	696	Q96KG9
RPDSWGEDNWEGLET	SCYL1	751	Q96KG9
EPAWEWEDAQGFSAL	NTN4	486	Q9HB63
SQATQTEPVWSEAGW	RASGRP3	611	Q8IV61
TEPVWSEAGWGDSGS	RASGRP3	616	Q8IV61
DSEGAPDSLWDWTVA	SPIB	36	Q01892
GGRVSTDDWPCDWVA	NOTCH4	1941	Q99466
PDESWESWAGNPSLT	SOWAHB	366	A6NEL2
DHWWQTETGSPITAS	ACSS3	446	Q9H6R3
EVGSSAVEQTWGWGD	APOBR	91	Q0VD83
EGTWQWVDGSPLSPS	CLEC4M	336	Q9H2X3
SQQRGGEQSWWGSDP	CLCN1	6	P35523
FANSSWSWVAPEGAG	CNNM3	71	Q8NE01
WSWVAPEGAGCREEA	CNNM3	76	Q8NE01
AWWSEGDATAQPGQL	TMEM61	36	Q8N0U2
DSADDGWSPWSEWTS	THBS1	376	P07996
GGWGAWENSTEVPRE	ZNF497	36	Q6ZNH5
SWSLTEDRDVSGEWP	ZNF324	81	O75467
TVGGHPSWSGWEDDA	TDRP	126	Q86YL5
WGQDPGVSANASKAW	PBXIP1	446	Q96AQ6
IDDAWWFGTIESQEP	PHIP	1076	Q8WWQ0
SWWGSGQTVLEQEAG	SPEG	186	Q15772
DWGWDLASDQSSPST	SLC2A4RG	156	Q9NR83
EDWAWQTDPSATGVG	SSC4D	306	Q8WTU2
ESGWWFVSTAEEQGW	SH3PXD2B	186	A1X283
VGGTDADEGEWPWQV	ST14	616	Q9Y5Y6
VGVEEASVDSWPWQV	TMPRSS4	206	Q9NRS4
WAQKAASGWGRDSPD	PRAG1	451	Q86YV5
ASPGLQDSWEWGGCS	WNT10A	201	Q9GZT5
ASRPWEGTDEPGSAW	TOR3A	26	Q9H497
WERADGSSLPEWVTD	PTK7	536	Q13308
TVVAGPEGYETQWWD	SERINC2	306	Q96SA4
DSGSWSWAQALPPEE	ZNF282	21	Q9UDV7
AFISWVEGEVEAWSP	ZNF785	76	A8K8V0
GWEDCKRSPAWNETG	TNRC6B	796	Q9UPQ9
SWEEEEDGGVWNTTG	TNRC6B	1011	Q9UPQ9
AVSSEGEWPWQASLQ	TMPRSS6	581	Q8IU80
SWVEEEAELWGPAAQ	ZNF764	76	Q96H86
SWSLTEDRDVSGEWP	ZNF324B	81	Q6AW86
TPGSWQSTIDPAWAA	UNQ6126/PRO20091	136	Q6UXV3
TAEVDLADDSWPGQW	NLRP13	466	Q86W25