Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF492 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 NR4A2 ZNF724 ADNP2 ZNF816 ZNF521 NR4A3 ZBTB41 ZNF510 ZNF860 SNAI1 NR4A1 ZNF468 ZBTB11 LHX6 ZNF98 ZIM3 ZNF583 ZNF879 PRDM1	8.39e-11	1412	85	26	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF492 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 ZNF335 NR4A2 ZNF724 ZNF816 ZNF521 NR4A3 ZBTB41 ZNF510 ZNF860 SNAI1 NR4A1 ZNF468 ZBTB11 LHX6 ZNF98 ZIM3 ZNF583 ZNF879 PRDM1	1.72e-10	1459	85	26	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF492 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 ZNF335 NR4A2 ZNF724 ZNF816 ZNF521 NR4A3 ZBTB41 ZNF860 SNAI1 NR4A1 ZNF468 ZBTB11 ZNF98 ZIM3 ZNF583 ZNF879 PRDM1	2.13e-10	1244	85	24	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF492 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 ZNF335 NR4A2 ZNF724 ZNF816 ZNF521 NR4A3 ZBTB41 ZNF860 SNAI1 NR4A1 ZNF468 ZBTB11 ZNF98 ZIM3 ZNF583 ZNF879 PRDM1	3.29e-10	1271	85	24	GO:0000987
GeneOntologyMolecularFunction	nuclear glucocorticoid receptor binding	NR4A2 NR4A3 NR4A1	8.05e-05	20	85	3	GO:0035259
GeneOntologyMolecularFunction	glial cell-derived neurotrophic factor receptor activity	GFRA1 GFRA2	1.78e-04	5	85	2	GO:0016167
GeneOntologyMolecularFunction	thioredoxin-disulfide reductase (NADPH) activity	TXNRD1 TXNRD3	3.71e-04	7	85	2	GO:0004791
GeneOntologyMolecularFunction	zinc ion binding	TCEA1 TCEA2 TCEA3 ZNF117 ADAMTS2 NR4A2 KMT2A NR4A3 NR4A1 PHF8 ZMYM4 NUP153	3.79e-04	891	85	12	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	TXNRD1 TCEA1 TCEA2 TCEA3 ZNF117 ADAMTS2 NR4A2 KMT2A CYP4F22 NR4A3 NR4A1 PHF8 ZMYM4 NUP153	4.67e-04	1189	85	14	GO:0046914
GeneOntologyMolecularFunction	protein-disulfide reductase (NAD(P)H) activity	TXNRD1 TXNRD3	6.32e-04	9	85	2	GO:0047134
GeneOntologyMolecularFunction	glycosaminoglycan binding	LAYN LIPG FGF7 APOH F11 GFRA2	9.97e-04	268	85	6	GO:0005539
GeneOntologyMolecularFunction	serine-type exopeptidase activity	CTSA F11	1.15e-03	12	85	2	GO:0070008
GeneOntologyMolecularFunction	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	TXNRD1 TXNRD3	1.15e-03	12	85	2	GO:0016668
GeneOntologyMolecularFunction	nuclear receptor activity	NR4A2 NR4A3 NR4A1	2.14e-03	60	85	3	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	NR4A2 NR4A3 NR4A1	2.24e-03	61	85	3	GO:0098531
GeneOntologyMolecularFunction	sulfur compound binding	LIPG LRP1 FGF7 APOH F11 GFRA2	2.56e-03	323	85	6	GO:1901681
GeneOntologyMolecularFunction	histone methyltransferase binding	ZNF335 PRDM1	2.62e-03	18	85	2	GO:1990226
GeneOntologyBiologicalProcess	cellular response to corticotropin-releasing hormone stimulus	NR4A2 NR4A3 NR4A1	1.20e-06	6	82	3	GO:0071376
GeneOntologyBiologicalProcess	response to corticotropin-releasing hormone	NR4A2 NR4A3 NR4A1	1.20e-06	6	82	3	GO:0043435
Domain	Znf_C2H2	ZNF492 ZNF800 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 ZNF335 TAX1BP1 ADNP2 ZNF816 ZNF521 ZBTB41 ZNF510 ZNF860 SNAI1 ZNF468 ZBTB11 ZNF98 ZIM3 ZNF583 ZNF879 ZNF702P PRDM1	1.28e-14	805	86	25	IPR007087
Domain	ZnF_C2H2	ZNF492 ZNF800 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 ZNF335 TAX1BP1 ADNP2 ZNF816 ZNF521 ZBTB41 ZNF510 ZNF860 SNAI1 ZNF468 ZBTB11 ZNF98 ZIM3 ZNF583 ZNF879 ZNF702P PRDM1	1.39e-14	808	86	25	SM00355
Domain	ZINC_FINGER_C2H2_2	ZNF492 ZNF800 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 ZNF335 ADNP2 ZNF816 ZNF521 ZBTB41 ZNF510 ZNF860 SNAI1 ZNF468 ZBTB11 ZNF98 ZIM3 ZNF583 ZNF879 ZNF702P PRDM1	5.19e-14	775	86	24	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF492 ZNF800 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 ZNF335 ADNP2 ZNF816 ZNF521 ZBTB41 ZNF510 ZNF860 SNAI1 ZNF468 ZBTB11 ZNF98 ZIM3 ZNF583 ZNF879 ZNF702P PRDM1	5.49e-14	777	86	24	PS00028
Domain	zf-C2H2_6	ZNF492 ZNF600 ZNF117 ZNF852 ZNF43 ZNF549 ZNF816 ZNF521 ZBTB41 ZNF860 SNAI1 ZNF468 ZBTB11 ZNF98 ZIM3 ZNF879 PRDM1	6.21e-14	314	86	17	PF13912
Domain	Znf_C2H2-like	ZNF492 ZNF800 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 ZNF335 TAX1BP1 ADNP2 ZNF816 ZNF521 ZBTB41 ZNF510 ZNF860 SNAI1 ZNF468 ZBTB11 ZNF98 ZIM3 ZNF583 ZNF879 PRDM1	9.28e-14	796	86	24	IPR015880
Domain	-	ZNF492 ZNF800 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 ZNF335 ZNF816 ZNF521 ZBTB41 ZNF510 ZNF860 SNAI1 ZNF468 ZBTB11 ZNF98 ZIM3 ZNF583 ZNF879 PRDM1	2.93e-13	679	86	22	3.30.160.60
Domain	zf-C2H2	ZNF492 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 ZNF335 ZNF816 ZNF521 ZBTB41 ZNF510 ZNF860 SNAI1 ZNF468 ZBTB11 ZNF98 ZIM3 ZNF583 ZNF879 ZNF702P PRDM1	4.41e-13	693	86	22	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF492 ZNF800 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 ZNF335 ZNF816 ZNF521 ZBTB41 ZNF510 ZNF860 SNAI1 ZNF468 ZBTB11 ZNF98 ZIM3 ZNF583 ZNF879 PRDM1	4.54e-13	694	86	22	IPR013087
Domain	KRAB	ZNF492 ZNF852 ZNF43 ZNF549 ZNF816 ZNF510 ZNF860 ZNF468 ZNF98 ZIM3 ZNF583 ZNF879	8.76e-08	358	86	12	PS50805
Domain	KRAB	ZNF492 ZNF852 ZNF43 ZNF549 ZNF816 ZNF510 ZNF860 ZNF468 ZNF98 ZIM3 ZNF583 ZNF879	8.76e-08	358	86	12	PF01352
Domain	TFSII	TCEA1 TCEA2 TCEA3	9.43e-08	3	86	3	IPR006289
Domain	Nuc_orph_rcpt	NR4A2 NR4A3 NR4A1	9.43e-08	3	86	3	IPR003070
Domain	KRAB	ZNF492 ZNF852 ZNF43 ZNF549 ZNF816 ZNF510 ZNF860 ZNF468 ZNF98 ZIM3 ZNF583 ZNF879	1.22e-07	369	86	12	SM00349
Domain	KRAB	ZNF492 ZNF852 ZNF43 ZNF549 ZNF816 ZNF510 ZNF860 ZNF468 ZNF98 ZIM3 ZNF583 ZNF879	1.25e-07	370	86	12	IPR001909
Domain	TF_IIS-rel	TCEA1 TCEA2 TCEA3	3.76e-07	4	86	3	IPR016492
Domain	Znf_TFIIS	TCEA1 TCEA2 TCEA3	1.87e-06	6	86	3	IPR001222
Domain	ZnF_C2C2	TCEA1 TCEA2 TCEA3	1.87e-06	6	86	3	SM00440
Domain	ZF_TFIIS_1	TCEA1 TCEA2 TCEA3	1.87e-06	6	86	3	PS00466
Domain	ZF_TFIIS_2	TCEA1 TCEA2 TCEA3	1.87e-06	6	86	3	PS51133
Domain	TFIIS_C	TCEA1 TCEA2 TCEA3	1.87e-06	6	86	3	PF01096
Domain	TFS2M	TCEA1 TCEA2 TCEA3	3.26e-06	7	86	3	SM00510
Domain	TFIIS_M	TCEA1 TCEA2 TCEA3	3.26e-06	7	86	3	PF07500
Domain	TFIIS_cen_dom	TCEA1 TCEA2 TCEA3	5.19e-06	8	86	3	IPR003618
Domain	-	TCEA1 TCEA2 TCEA3	5.19e-06	8	86	3	1.10.472.30
Domain	TFIIS_CENTRAL	TCEA1 TCEA2 TCEA3	5.19e-06	8	86	3	PS51321
Domain	TFIIS/CRSP70_N_sub	TCEA1 TCEA2 TCEA3	1.11e-05	10	86	3	IPR003617
Domain	TFS2N	TCEA1 TCEA2 TCEA3	1.11e-05	10	86	3	SM00509
Domain	Glial_neurotroph_fac_rcpt_a1/2	GFRA1 GFRA2	2.10e-05	2	86	2	IPR017372
Domain	-	TCEA1 TCEA2 TCEA3	2.61e-05	13	86	3	1.20.930.10
Domain	TFIIS_N	TCEA1 TCEA2 TCEA3	2.61e-05	13	86	3	PS51319
Domain	Med26	TCEA1 TCEA2 TCEA3	2.61e-05	13	86	3	PF08711
Domain	TFIIS_N	TCEA1 TCEA2 TCEA3	3.31e-05	14	86	3	IPR017923
Domain	Thioredoxin/glutathione_Rdtase	TXNRD1 TXNRD3	6.27e-05	3	86	2	IPR006338
Domain	Pyr_OxRdtase_I_AS	TXNRD1 TXNRD3	2.08e-04	5	86	2	IPR012999
Domain	Pyr_redox_dim	TXNRD1 TXNRD3	2.08e-04	5	86	2	PF02852
Domain	GDNF_rcpt	GFRA1 GFRA2	2.08e-04	5	86	2	IPR003438
Domain	PYRIDINE_REDOX_1	TXNRD1 TXNRD3	2.08e-04	5	86	2	PS00076
Domain	GDNF	GFRA1 GFRA2	3.11e-04	6	86	2	SM00907
Domain	GDNF	GFRA1 GFRA2	3.11e-04	6	86	2	PF02351
Domain	GDNF/GAS1	GFRA1 GFRA2	3.11e-04	6	86	2	IPR016017
Domain	GLUTAREDOXIN_1	TXNRD1 TXNRD3	3.11e-04	6	86	2	PS00195
Domain	-	TXNRD1 TXNRD3	4.34e-04	7	86	2	3.30.390.30
Domain	Pyr_nucl-diS_OxRdtase_dimer	TXNRD1 TXNRD3	5.76e-04	8	86	2	IPR004099
Domain	FAD/NAD-linked_Rdtase_dimer	TXNRD1 TXNRD3	5.76e-04	8	86	2	IPR016156
Domain	Glutaredoxin	TXNRD1 TXNRD3	7.39e-04	9	86	2	PF00462
Domain	GLUTAREDOXIN_2	TXNRD1 TXNRD3	7.39e-04	9	86	2	PS51354
Domain	SET	KMT2A KMT2E PRDM1	8.85e-04	41	86	3	PF00856
Domain	Glutaredoxin	TXNRD1 TXNRD3	9.21e-04	10	86	2	IPR002109
Domain	SET	KMT2A KMT2E PRDM1	1.24e-03	46	86	3	SM00317
Domain	zf-C4	NR4A2 NR4A3 NR4A1	1.24e-03	46	86	3	PF00105
Domain	Znf_hrmn_rcpt	NR4A2 NR4A3 NR4A1	1.24e-03	46	86	3	IPR001628
Domain	Nuclear_hrmn_rcpt	NR4A2 NR4A3 NR4A1	1.24e-03	46	86	3	IPR001723
Domain	NUCLEAR_REC_DBD_2	NR4A2 NR4A3 NR4A1	1.24e-03	46	86	3	PS51030
Domain	NUCLEAR_REC_DBD_1	NR4A2 NR4A3 NR4A1	1.24e-03	46	86	3	PS00031
Domain	ZnF_C4	NR4A2 NR4A3 NR4A1	1.24e-03	46	86	3	SM00399
Domain	-	NR4A2 NR4A3 NR4A1	1.32e-03	47	86	3	1.10.565.10
Domain	HOLI	NR4A2 NR4A3 NR4A1	1.40e-03	48	86	3	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	NR4A2 NR4A3 NR4A1	1.40e-03	48	86	3	IPR000536
Domain	Hormone_recep	NR4A2 NR4A3 NR4A1	1.40e-03	48	86	3	PF00104
Domain	SET_dom	KMT2A KMT2E PRDM1	1.58e-03	50	86	3	IPR001214
Domain	SET	KMT2A KMT2E PRDM1	1.58e-03	50	86	3	PS50280
Domain	Anticodon-bd	BRIX1 EIF2AK4	1.84e-03	14	86	2	IPR004154
Domain	-	NR4A2 NR4A3 NR4A1	2.31e-03	57	86	3	3.30.50.10
Domain	Znf_NHR/GATA	NR4A2 NR4A3 NR4A1	2.42e-03	58	86	3	IPR013088
Domain	EGF	LRP1 SCUBE3 AREG TMEFF2	2.74e-03	126	86	4	PF00008
Domain	Prtase_inh_Kunz-CS	SPINT2 EPPIN	3.06e-03	18	86	2	IPR020901
Domain	KU	SPINT2 EPPIN	3.06e-03	18	86	2	SM00131
Domain	PLAC	ADAMTSL1 ADAMTS2	3.41e-03	19	86	2	PS50900
Domain	BPTI_KUNITZ_2	SPINT2 EPPIN	3.41e-03	19	86	2	PS50279
Domain	PLAC	ADAMTSL1 ADAMTS2	3.41e-03	19	86	2	IPR010909
Domain	Kunitz_BPTI	SPINT2 EPPIN	3.41e-03	19	86	2	PF00014
Domain	Pyr_redox_2	TXNRD1 TXNRD3	3.41e-03	19	86	2	PF07992
Domain	BPTI_KUNITZ_1	SPINT2 EPPIN	3.41e-03	19	86	2	PS00280
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	TXNRD1 TCEA1 ZNF492 ZNF600 ZNF43 USP9X ZNF549 ICE2 NR4A2 ZNF724 ZNF521 KMT2A NR4A3 RFFL ZNF510 ZNF860 NR4A1 ZNF468 ZIM3 ZNF583 PRDM1	5.31e-07	1387	65	21	M734
Pubmed	Nuclear receptors of the NR4a family are not required for the development and function of follicular T helper cells.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	25899083
Pubmed	NR4A nuclear receptors support memory enhancement by histone deacetylase inhibitors.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	22996661
Pubmed	Altered NR4A Subfamily Gene Expression Level in Peripheral Blood of Parkinson's and Alzheimer's Disease Patients.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	27159982
Pubmed	Inhibition of adipocyte differentiation by Nur77, Nurr1, and Nor1.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	18945812
Pubmed	The nuclear receptors NUR77, NURR1 and NOR1 in obesity and during fat loss.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	22143616
Pubmed	Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	16873729
Pubmed	The orphan nuclear receptor Nur77 is a determinant of myofiber size and muscle mass in mice.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	25605333
Pubmed	Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	15964844
Pubmed	Relevance of the NR4A sub-family of nuclear orphan receptors in trophoblastic BeWo cell differentiation.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	28808448
Pubmed	The NR4A receptors Nurr1 and Nur77 are increased in human placenta from women with gestational diabetes.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	25199433
Pubmed	NR4A nuclear receptors in immunity and atherosclerosis.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	24005216
Pubmed	Minireview: What is Known about SUMOylation Among NR4A Family Members?	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	34437889
Pubmed	Stress and glucocorticoid regulation of NR4A genes in mice.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	24753204
Pubmed	Differential regulation of Nr4a subfamily nuclear receptors following mast cell activation.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	21621845
Pubmed	Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	10523643
Pubmed	Replicated association of the NR4A3 gene with smoking behaviour in schizophrenia and in bipolar disorder.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	20659174
Pubmed	Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	36482877
Pubmed	Nuclear receptor 4A (NR4A) family - orphans no more.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	25917081
Pubmed	FGF-8 stimulates the expression of NR4A orphan nuclear receptors in osteoblasts.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	18809462
Pubmed	NR4A transcription factors limit CAR T cell function in solid tumours.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	30814732
Pubmed	The NR4A orphan nuclear receptors: mediators in metabolism and diseases.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	25089663
Pubmed	Beta-adrenergic signaling regulates NR4A nuclear receptor and metabolic gene expression in multiple tissues.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	19465082
Pubmed	MSKs are required for the transcription of the nuclear orphan receptors Nur77, Nurr1 and Nor1 downstream of MAPK signalling.	NR4A2 NR4A3 NR4A1	1.51e-08	3	87	3	15910281
Pubmed	TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion.	NR4A2 NR4A3 NR4A1	6.04e-08	4	87	3	31152140
Pubmed	Trained immunity induced by high-salt diet impedes stroke recovery.	NR4A2 NR4A3 NR4A1	6.04e-08	4	87	3	37965920
Pubmed	Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis.	NR4A2 NR4A3 NR4A1	6.04e-08	4	87	3	23334790
Pubmed	Evaluation of mRNA Expressions of TOX and NR4As in CD8+ T cells in Acute Leukemia.	NR4A2 NR4A3 NR4A1	6.04e-08	4	87	3	37961948
Pubmed	Dual function of Pin1 in NR4A nuclear receptor activation: enhanced activity of NR4As and increased Nur77 protein stability.	NR4A2 NR4A3 NR4A1	6.04e-08	4	87	3	22789442
Pubmed	Nr4a Receptors Regulate Development and Death of Labile Treg Precursors to Prevent Generation of Pathogenic Self-Reactive Cells.	NR4A2 NR4A3 NR4A1	6.04e-08	4	87	3	30089271
Pubmed	Parathyroid hormone induces the NR4A family of nuclear orphan receptors in vivo.	NR4A2 NR4A3 NR4A1	6.04e-08	4	87	3	15910753
Pubmed	Vascular endothelial growth factor-regulated gene expression in endothelial cells: KDR-mediated induction of Egr3 and the related nuclear receptors Nur77, Nurr1, and Nor1.	NR4A2 NR4A3 NR4A1	6.04e-08	4	87	3	14525795
Pubmed	Regulation of peripheral Th/Treg differentiation and suppression of airway inflammation by Nr4a transcription factors.	NR4A2 NR4A3 NR4A1	6.04e-08	4	87	3	33665581
Pubmed	Heterogeneity and tissue-specific expression of eukaryotic transcription factor S-II-related protein mRNA.	TCEA1 TCEA2 TCEA3	1.51e-07	5	87	3	1917889
Pubmed	The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation.	NR4A2 NR4A3 NR4A1	1.51e-07	5	87	3	15155786
Pubmed	Transcription elongation factor Tcea3 regulates the pluripotent differentiation potential of mouse embryonic stem cells via the Lefty1-Nodal-Smad2 pathway.	TCEA1 TCEA2 TCEA3	1.51e-07	5	87	3	23169579
Pubmed	Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells.	NR4A2 NR4A3 NR4A1	1.51e-07	5	87	3	26304965
Pubmed	Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1.	NR4A2 NR4A3 NR4A1	1.51e-07	5	87	3	8961274
Pubmed	NR4A receptors up-regulate the antiproteinase alpha-2 macroglobulin (A2M) and modulate MMP-2 and MMP-9 in vascular smooth muscle cells.	NR4A2 NR4A3 NR4A1	3.01e-07	6	87	3	25809189
Pubmed	Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation.	NR4A2 NR4A3 NR4A1	8.39e-07	8	87	3	16223362
Pubmed	GDNF and GFRalpha1 promote differentiation and tangential migration of cortical GABAergic neurons.	LHX6 GFRA1 GFRA2	1.79e-06	10	87	3	15748846
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MORF4L2 USP9X SYNE1 SMC1A NR4A2 ADNP2 LRP1 ZNF521 RAB11FIP4 CTNND2 ZBTB11 ZNF583 ZMYM4 ZNF879	3.59e-06	1285	87	14	35914814
Pubmed	Transcriptional Profiling of Monocytes Deficient in Nuclear Orphan Receptors NR4A2 and NR4A3 Reveals Distinct Signalling Roles Related to Antigen Presentation and Viral Response.	NR4A2 NR4A3	6.19e-06	2	87	2	34248958
Pubmed	Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins.	GFRA1 GFRA2	6.19e-06	2	87	2	9177201
Pubmed	Compensatory Expression of Nur77 and Nurr1 Regulates NF-κB-Dependent Inflammatory Signaling in Astrocytes.	NR4A2 NR4A1	6.19e-06	2	87	2	30111648
Pubmed	Differential roles for Nr4a1 and Nr4a2 in object location vs. object recognition long-term memory.	NR4A2 NR4A1	6.19e-06	2	87	2	23161447
Pubmed	The orphan nuclear receptor Nor1/Nr4a3 is a negative regulator of β-cell mass.	NR4A3 NR4A1	6.19e-06	2	87	2	30696767
Pubmed	Protein kinase C regulates mitochondrial targeting of Nur77 and its family member Nor-1 in thymocytes undergoing apoptosis.	NR4A3 NR4A1	6.19e-06	2	87	2	20411565
Pubmed	Nuclear receptors Nur77 and Nurr1 modulate mesenchymal stromal cell migration.	NR4A2 NR4A1	6.19e-06	2	87	2	21480782
Pubmed	NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes.	NR4A3 NR4A1	6.19e-06	2	87	2	28249906
Pubmed	Molecular signatures of thyroid follicular neoplasia.	NR4A3 NR4A1	6.19e-06	2	87	2	20668010
Pubmed	ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia.	ZNF521 KMT2A	6.19e-06	2	87	2	28412727
Pubmed	The orphan nuclear receptors NURR1 and NGFI-B modulate aromatase gene expression in ovarian granulosa cells: a possible mechanism for repression of aromatase expression upon luteinizing hormone surge.	NR4A2 NR4A1	6.19e-06	2	87	2	15486232
Pubmed	A minority of cases of acinic cell carcinoma of the salivary glands are driven by an NR4A2 rearrangement: the diagnostic utility of the assessment of NR4A2 and NR4A3 alterations in salivary gland tumors.	NR4A2 NR4A3	6.19e-06	2	87	2	36469101
Pubmed	The nuclear orphan receptor NR4A1 and NR4A3 as tumor suppressors in hematologic neoplasms.	NR4A3 NR4A1	6.19e-06	2	87	2	25410408
Pubmed	Molecular cloning of cDNA and tissue-specific expression of the gene for SII-K1, a novel transcription elongation factor SII.	TCEA1 TCEA3	6.19e-06	2	87	2	9685180
Pubmed	Deficiency of the NR4A neuron-derived orphan receptor-1 attenuates neointima formation after vascular injury.	NR4A3 NR4A1	6.19e-06	2	87	2	19153266
Pubmed	Orphan Nuclear Receptor Family 4A (NR4A) Members NR4A2 and NR4A3 Selectively Modulate Elements of the Monocyte Response to Buffered Hypercapnia.	NR4A2 NR4A3	6.19e-06	2	87	2	38474099
Pubmed	HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML.	NR4A3 NR4A1	6.19e-06	2	87	2	23247046
Pubmed	Transcription factor genes and the developing eye: a genetic perspective.	TCEA2 TCEA3	6.19e-06	2	87	2	8875254
Pubmed	Nur-related factor 1 and nerve growth factor-induced clone B in human adrenal cortex and its disorders.	NR4A2 NR4A1	6.19e-06	2	87	2	15292355
Pubmed	Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia.	NR4A3 NR4A1	6.19e-06	2	87	2	17515897
Pubmed	Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice.	NR4A3 NR4A1	6.19e-06	2	87	2	21205929
Pubmed	CUG start codon generates thioredoxin/glutathione reductase isoforms in mouse testes.	TXNRD1 TXNRD3	6.19e-06	2	87	2	20018845
Pubmed	Nuclear NR4A2 (Nurr1) Immunostaining is a Novel Marker for Acinic Cell Carcinoma of the Salivary Glands Lacking the Classic NR4A3 (NOR-1) Upregulation.	NR4A2 NR4A3	6.19e-06	2	87	2	32341238
Pubmed	Cloning, mRNA distribution and chromosomal localisation of the gene for glial cell line-derived neurotrophic factor receptor beta, a homologue to GDNFR-alpha.	GFRA1 GFRA2	6.19e-06	2	87	2	9259272
Pubmed	Identification of a new brain-specific transcription factor, NURR1.	NR4A2 NR4A1	6.19e-06	2	87	2	1491694
Pubmed	NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival.	NR4A2 NR4A3	6.19e-06	2	87	2	28637666
Pubmed	BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion.	NR4A3 PRDM1	6.19e-06	2	87	2	36350986
Pubmed	TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.	NR4A2 NR4A3 NR4A1	6.73e-06	15	87	3	19321449
Pubmed	Nur77 deletion impairs muscle growth during developmental myogenesis and muscle regeneration in mice.	NR4A2 NR4A3 NR4A1	8.27e-06	16	87	3	28170423
Pubmed	HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors.	TCEA1 TCEA2 TCEA3	1.00e-05	17	87	3	1559613
Pubmed	Identification of a Pax6-dependent epidermal growth factor family signaling source at the lateral edge of the embryonic cerebral cortex.	FGF7 AREG TMEFF2	1.42e-05	19	87	3	12878679
Pubmed	GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival.	GFRA1 GFRA2	1.85e-05	3	87	2	10774729
Pubmed	Genome-wide profiling reveals transcriptional repression of MYC as a core component of NR4A tumor suppression in acute myeloid leukemia.	NR4A3 NR4A1	1.85e-05	3	87	2	23552735
Pubmed	Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair.	NR4A2 NR4A1	1.85e-05	3	87	2	21979916
Pubmed	Angiotensin II triggers expression of the adrenal gland zona glomerulosa-specific 3β-hydroxysteroid dehydrogenase isoenzyme through de novo protein synthesis of the orphan nuclear receptors NGFIB and NURR1.	NR4A2 NR4A1	1.85e-05	3	87	2	25092869
Pubmed	Evaluation of germline sequence variants of GFRA1, GFRA2, and GFRA3 genes in a cohort of Spanish patients with sporadic medullary thyroid cancer.	GFRA1 GFRA2	1.85e-05	3	87	2	12490080
Pubmed	Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells.	GFRA1 GFRA2	1.85e-05	3	87	2	15589513
Pubmed	NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3.	NR4A2 NR4A1	1.85e-05	3	87	2	7877627
Pubmed	Microbiota-derived short chain fatty acid promotion of Amphiregulin expression by dendritic cells is regulated by GPR43 and Blimp-1.	AREG PRDM1	1.85e-05	3	87	2	32958255
Pubmed	NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPα and inflammatory signaling.	NR4A3 NR4A1	1.85e-05	3	87	2	29343483
Pubmed	Protein-protein interactions and transcriptional antagonism between the subfamily of NGFI-B/Nur77 orphan nuclear receptors and glucocorticoid receptor.	NR4A2 NR4A1	1.85e-05	3	87	2	15591535
Pubmed	Deficiency of the NR4A orphan nuclear receptor NOR1 decreases monocyte adhesion and atherosclerosis.	NR4A3 NR4A1	1.85e-05	3	87	2	20558821
Pubmed	Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases.	TXNRD1 TXNRD3	1.85e-05	3	87	2	10455115
Pubmed	Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems.	TXNRD1 TXNRD3	1.85e-05	3	87	2	11259642
Pubmed	Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis.	NR4A3 NR4A1	1.85e-05	3	87	2	9155013
Pubmed	Isolation and characterization of a cDNA encoding a new type of human transcription elongation factor S-II.	TCEA1 TCEA2	1.85e-05	3	87	2	8566795
Pubmed	Antithrombotic Effects of Nur77 and Nor1 Are Mediated Through Upregulating Thrombomodulin Expression in Endothelial Cells.	NR4A3 NR4A1	1.85e-05	3	87	2	26634653
Pubmed	Orphan nuclear receptors in T lymphocyte development.	NR4A3 NR4A1	1.85e-05	3	87	2	12223510
Pubmed	Tissue distribution of Ret, GFRalpha-1, GFRalpha-2 and GFRalpha-3 receptors in the human brainstem at fetal, neonatal and adult age.	GFRA1 GFRA2	1.85e-05	3	87	2	17825269
Pubmed	Mesenchymal COX2-PG secretome engages NR4A-WNT signalling axis in haematopoietic progenitors to suppress anti-leukaemia immunity.	NR4A2 NR4A1	1.85e-05	3	87	2	30106181
Pubmed	B cell lymphoma 2 (Bcl-2) residues essential for Bcl-2's apoptosis-inducing interaction with Nur77/Nor-1 orphan steroid receptors.	NR4A3 NR4A1	1.85e-05	3	87	2	29414782
Pubmed	Selective ligand activity at Nur/retinoid X receptor complexes revealed by dimer-specific bioluminescence resonance energy transfer-based sensors.	NR4A2 NR4A1	1.85e-05	3	87	2	26148973
Pubmed	Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR alpha2, a functional neurturin receptor.	GFRA1 GFRA2	1.85e-05	3	87	2	10069331
Pubmed	Genetic association of the GDNF alpha-receptor genes with schizophrenia and clozapine response.	GFRA1 GFRA2	1.85e-05	3	87	2	20116071
Pubmed	Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2'.	LRP1 APOH	1.85e-05	3	87	2	12807892
Pubmed	Site-specific gene expression and localization of growth factor ligand receptors RET, GFRα1 and GFRα2 in human adult colon.	GFRA1 GFRA2	1.85e-05	3	87	2	23881409
Pubmed	Genome-scale study of transcription factor expression in the branching mouse lung.	TCEA1 TCEA2 SNAI1 LHX6	2.48e-05	67	87	4	22711520
Pubmed	Molecular cloning and characterization of cDNA for eukaryotic transcription factor S-II.	TCEA1 TCEA3	3.70e-05	4	87	2	3346229
Pubmed	GFRalpha-3, a protein related to GFRalpha-1, is expressed in developing peripheral neurons and ensheathing cells.	GFRA1 GFRA2	3.70e-05	4	87	2	9749804
Cytoband	19q13.41	ZNF600 ZNF816 ZNF468 ZNF702P	1.61e-05	78	88	4	19q13.41
Cytoband	12q23-q24.1	TXNRD1 PLA2G1B	5.42e-05	6	88	2	12q23-q24.1
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF492 ZNF43 ZNF724 ZNF98	9.31e-05	122	88	4	chr19p12
Cytoband	19p12	ZNF492 ZNF724 ZNF98	7.09e-04	90	88	3	19p12
Cytoband	Xq22	MORF4L2 FRMPD3	8.18e-04	22	88	2	Xq22
Cytoband	Ensembl 112 genes in cytogenetic band chr20q13	TCEA2 EPPIN ZNF335 SNAI1 CTSA	1.34e-03	422	88	5	chr20q13
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF600 SPINT2 ZNF549 ZNF816 ZNF468 ZIM3 ZNF583 ZNF702P	2.08e-03	1192	88	8	chr19q13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF492 ZNF800 ZNF600 ZNF117 ZNF852 ZNF341 ZNF43 ZNF549 ZNF335 ADNP2 ZNF816 ZNF521 ZBTB41 ZNF510 ZNF860 SNAI1 ZNF468 ZBTB11 ZNF98 ZIM3 ZNF583 ZNF879 PRDM1	8.85e-17	718	63	23	28
GeneFamily	Nuclear hormone receptors	NR4A2 NR4A3 NR4A1	6.63e-04	49	63	3	71
GeneFamily	Selenoproteins	TXNRD1 TXNRD3	3.40e-03	25	63	2	890
GeneFamily	PHD finger proteins	KMT2A PHF8 KMT2E	3.82e-03	90	63	3	88
Coexpression	GSE17974_0H_VS_0.5H_IN_VITRO_ACT_CD4_TCELL_DN	TXNRD1 NR4A2 NR4A3 NR4A1 DCTN4 TASL AREG	3.61e-06	192	87	7	M4154
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPINT2 LAYN NR4A2 NR4A3 EIF2AK4 SNAI1 AREG	1.06e-07	191	88	7	6cda82a994f4b205cf54590c979d7c9f3be2b4c8
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPINT2 LAYN NR4A2 NR4A3 EIF2AK4 SNAI1 AREG	1.06e-07	191	88	7	4257f02856f3510981e9f84d465d91448d6126e2
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPINT2 LAYN NR4A2 NR4A3 EIF2AK4 SNAI1 AREG	1.06e-07	191	88	7	2699e9bb872f2b561bb976dfdc2746e359bc9daf
ToppCell	(3)_MNP-(3)_DC_2\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	SPINT2 NR4A2 NR4A3 NR4A1 TASL AREG PRDM1	1.06e-07	191	88	7	3ff163484af8c12ef4eef87246cf044257fd2547
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPINT2 LAYN NR4A2 NR4A3 EIF2AK4 SNAI1 AREG	1.06e-07	191	88	7	4b94c8b0183ae07d173646b7e7e1d9db04ec9637
ToppCell	Control-cDC-\|Control / Disease condition and Cell class	TCEA3 SPINT2 LAYN NR4A2 NR4A3 EIF2AK4 AREG	1.22e-07	195	88	7	a2b4d9473eff73f088b247ce43e66f013622471e
ToppCell	Control-cDC\|Control / Disease condition and Cell class	TCEA3 SPINT2 LAYN NR4A2 NR4A3 EIF2AK4 AREG	1.22e-07	195	88	7	b96acdd22dd3885af69328f170ea871a0d570034
ToppCell	COVID-19_Severe-cDC\|COVID-19_Severe / disease group, cell group and cell class	LAYN NR4A2 EMILIN2 NR4A3 SNAI1 NR4A1 AREG	1.22e-07	195	88	7	6419090b19de7b5d5140eaecf231860273da2c0d
ToppCell	mild_COVID-19-cDC\|World / disease group, cell group and cell class (v2)	SPINT2 LAYN NR4A3 EIF2AK4 SNAI1 NR4A1 AREG	1.30e-07	197	88	7	63e7b040c64f1e28b8db79980c7b580caa7d1b95
ToppCell	BAL-Control-cDC_5\|Control / Compartment, Disease Groups and Clusters	NR4A2 EMILIN2 NR4A3 SNAI1 NR4A1 AREG PRDM1	1.30e-07	197	88	7	8a3fe59be3ed1f0254cc8c60b99c840193370efb
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	NR4A2 NR4A3 SNAI1 NR4A1 AREG PRDM1	6.76e-07	156	88	6	029ba0832ee9c4a2c85620e4df2260e02d86b45c
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	NR4A2 NR4A3 SNAI1 NR4A1 AREG PRDM1	6.76e-07	156	88	6	5df19a235843829f5a1a90ca21b0964ef8b4e115
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD1c+_DCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	ZNF521 NR4A3 SNAI1 NR4A1 TASL GFRA2	1.66e-06	182	88	6	551d301adfb4d5046c5f60f6996450621b04e9b2
ToppCell	PBMC-Mild-cDC_5\|Mild / Compartment, Disease Groups and Clusters	NR4A2 NR4A3 SNAI1 NR4A1 AREG PRDM1	1.94e-06	187	88	6	0afef5baf3752314dbfb024790347d5e51f9b84b
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_8\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPINT2 LAYN NR4A2 NR4A3 SNAI1 NR4A1	2.00e-06	188	88	6	8431991e68b8e9c5eb72212460f6da679ea3b85a
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_8\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPINT2 LAYN NR4A2 NR4A3 SNAI1 NR4A1	2.00e-06	188	88	6	d8f10b3ad11bc99a63f44560e39791085256e5c8
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPINT2 LAYN NR4A3 SNAI1 NR4A1 AREG	2.07e-06	189	88	6	c81b38cda4525254fe4fa137a4c9bc9abe0363bb
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPINT2 LAYN NR4A3 SNAI1 NR4A1 AREG	2.07e-06	189	88	6	807922b5ea0faddd3abfa9ec1b53f3f2b00e61bf
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_5\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPINT2 NR4A2 NR4A3 NR4A1 GFRA2 AREG	2.20e-06	191	88	6	92c5a26b90a55831039220341d863cf2940f3c9b
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_5\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPINT2 NR4A2 NR4A3 NR4A1 GFRA2 AREG	2.26e-06	192	88	6	6184163dbfca882824cb266bb9030d9f79e3acb0
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPINT2 NR4A2 NR4A3 SNAI1 NR4A1 AREG	2.26e-06	192	88	6	dfb9101622f7d2f2c392e850cff07becfc8c655e
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPINT2 NR4A2 NR4A3 SNAI1 NR4A1 AREG	2.26e-06	192	88	6	d39133cf1a20af6f2970188630fc3b27a4cfc9c5
ToppCell	367C-Myeloid-Dendritic-cDC2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SPINT2 NR4A2 NR4A3 NR4A1 TASL AREG	2.33e-06	193	88	6	940e9a419d0de1f9e72b5cc9c86684057003be58
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NR4A2 NR4A3 SNAI1 NR4A1 AREG PRDM1	2.33e-06	193	88	6	704378de39e1b6f108ab5b0ecbd594d414ec8ae4
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ZNF600 SYNE1 SMC1A PLA2G1B CMC4 AREG	2.40e-06	194	88	6	6be74e4ba631b0c46cef2c580553f4c1ed29579e
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NR4A2 NR4A3 SNAI1 NR4A1 AREG PRDM1	2.40e-06	194	88	6	36f8ae4f2b3bf802f6ff0e9fc79e7f170f96ae8b
ToppCell	343B-Myeloid-Dendritic-cDC2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SPINT2 NR4A2 NR4A3 NR4A1 TASL AREG	2.40e-06	194	88	6	ccb04f0788c98e0f63f18b09484d75ac536412a1
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTSL1 ADAMTS2 FGF7 NR4A3 NR4A1 GFRA1	2.48e-06	195	88	6	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	SPINT2 NR4A2 NR4A3 NR4A1 AREG PRDM1	2.48e-06	195	88	6	7fb5c0911ff09580515d1a1827d7249d6242630c
ToppCell	COVID-19_Moderate-cDC\|World / disease group, cell group and cell class	SPINT2 EMILIN2 NR4A3 EIF2AK4 SNAI1 NR4A1	2.55e-06	196	88	6	92a236adf386f05d020b1954bbdc5bd32346cbf0
ToppCell	tumor_Lung-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	NR4A2 NR4A3 SNAI1 NR4A1 KMT2E PRDM1	2.55e-06	196	88	6	7aa6778b78a8549dd4d0a5278ef8017334b00c38
ToppCell	COVID-19_Mild-cDC\|COVID-19_Mild / Disease condition and Cell class	TCEA3 SPINT2 LAYN NR4A2 NR4A3 AREG	2.63e-06	197	88	6	09045845891de79164124afb6c632e2838906006
ToppCell	normal_Lymph_Node-Myeloid_cells-CD1c+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	SPINT2 NR4A2 NR4A3 SNAI1 NR4A1 AREG	2.63e-06	197	88	6	2b3cd318c988364adcba4441444045914d58fe46
ToppCell	COVID-19_Mild-cDC-\|COVID-19_Mild / Disease condition and Cell class	TCEA3 SPINT2 LAYN NR4A2 NR4A3 AREG	2.63e-06	197	88	6	61d6dd023b2ba2bc76f17c06f7c30434ed865171
ToppCell	mLN-B_cell-B_cell_memory\|B_cell / Region, Cell class and subclass	TCEA1 NR4A2 NR4A3 NR4A1 CTSA AREG	2.70e-06	198	88	6	e2c63ca9f82f8524447e398b11a676b22d2f58ce
ToppCell	tumor_Lung-Myeloid_cells-CD1c+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	SPINT2 NR4A2 NR4A3 SNAI1 NR4A1 AREG	2.70e-06	198	88	6	edd8ad006c4c7516491e52cc8adad20297837e5b
ToppCell	COVID-19_Severe-cDC\|World / disease group, cell group and cell class	SPINT2 EMILIN2 NR4A3 SNAI1 NR4A1 AREG	2.70e-06	198	88	6	c452334249f047265ae89dcabe7de446d968cae6
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRP1 ZNF521 FGF7 NR4A1 ZNF98 GFRA1	2.78e-06	199	88	6	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCell	Control-Control-Myeloid-cDC\|Control / Disease, condition lineage and cell class	SPINT2 LAYN NR4A2 EMILIN2 NR4A3 EIF2AK4	2.86e-06	200	88	6	1375d199320feb85ba06e74b10df6521e790addf
ToppCell	COVID-19-COVID-19_Severe-Myeloid-cDC\|COVID-19_Severe / Disease, condition lineage and cell class	SPINT2 LAYN NR4A3 EIF2AK4 NR4A1 AREG	2.86e-06	200	88	6	e7b808d8ed65343a4345fafb03015fe4f7ce302f
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS2 SYNE1 LRP1 ZNF521 FGF7 GFRA1	2.86e-06	200	88	6	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	Biopsy_Other_PF-Immune-cDCs\|Biopsy_Other_PF / Sample group, Lineage and Cell type	SPINT2 NR4A2 NR4A3 EIF2AK4 TASL AREG	2.86e-06	200	88	6	8e455f685f0a9c63e83d6d339d7767f0e9841c6e
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NR4A2 EMILIN2 LRP1 NR4A3 NR4A1 AREG	2.86e-06	200	88	6	09bac15df511687ff336c1e7a67d980c6c281f79
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTSL1 ADAMTS2 SYNE1 LRP1 FGF7 GFRA1	2.86e-06	200	88	6	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	RA-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	MFSD2A LAYN ZNF852 NR4A3 AREG	8.06e-06	138	88	5	5a713f24f633de463ef47ca37fbb2bb60c7fdb77
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS2 NR4A2 NR4A3 NR4A1 AREG	1.37e-05	154	88	5	874b1220337276489a89fcc9a39bc81ba6b68baf
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EMILIN2 CTNND2 LHX6 TMEFF2 PRDM1	1.42e-05	155	88	5	5c7b68b59244525e3714806c205a57a2daebf423
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_8\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NR4A2 NR4A3 NR4A1 TASL AREG	1.70e-05	161	88	5	7e0b8119cea208c0b4a0dffdf94ff6137d0b4c90
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_8\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NR4A2 NR4A3 NR4A1 TASL AREG	1.75e-05	162	88	5	2fd6e8f48b48d509a7533cec2f79089513c34a2f
ToppCell	normal_Lymph_Node-Myeloid_cells-Monocytes\|Myeloid_cells / Location, Cell class and cell subclass	NR4A2 NR4A3 NR4A1 AREG PRDM1	1.80e-05	163	88	5	7d7f18e5c99be125e95bc180823430291b770d05
ToppCell	normal_Lung-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	NR4A2 NR4A3 NR4A1 AREG PRDM1	1.97e-05	166	88	5	07b498eb341abec02a3ccaae320bdbb5cd6883c5
ToppCell	COVID-19-Myeloid-MoAM5,_CCL3L1\|Myeloid / Condition, Lineage and Cell class	MFSD2A NR4A2 NR4A3 NR4A1 AREG	2.09e-05	168	88	5	ea465152ea31391b63c02425beafa9a4f51f6703
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ADAMTS2 EMILIN2 LRP1 TMEFF2	2.15e-05	169	88	5	bb43abad2c049b7f4d307737347290e01b3339a3
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ADAMTS2 EMILIN2 LRP1 TMEFF2	2.15e-05	169	88	5	5f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ADAMTS2 EMILIN2 LRP1 TMEFF2	2.15e-05	169	88	5	8bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NR4A2 LRP1 NR4A3 NR4A1 GFRA2	2.27e-05	171	88	5	5e93c76ee60f9d0590ebb140812653a5e1369417
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTSL1 LRP1 FGF7 GFRA1 TMEFF2	2.34e-05	172	88	5	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	COVID-19-Myeloid-MoAM5,_CCL3L1\|COVID-19 / Condition, Lineage and Cell class	MFSD2A NR4A2 NR4A3 NR4A1 AREG	2.40e-05	173	88	5	502f888b7684ed39f5c577eedcacf673ae81d39e
ToppCell	facs-SCAT-Fat-24m-Lymphocytic-NK_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFSD2A SPINT2 NR4A3 F11 AREG	2.54e-05	175	88	5	d82153bdb0c5cca96485d6b0579440f9c9e3abe2
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR4A2 PLA2G1B RAB11FIP4 AREG PRDM1	2.61e-05	176	88	5	feafc757e7aa4f17128ff34886beb2fd3461c9ea
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LAYN NR4A2 NR4A3 NR4A1 AREG	2.68e-05	177	88	5	3a150dcaefa342d49968b42c7cdb1fbb633adcd0
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LAYN NR4A2 NR4A3 NR4A1 AREG	2.68e-05	177	88	5	c9e5820ff0bc7ad1adcfb2651713fdfc58bced56
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	ADAMTSL1 ADAMTS2 SYNE1 LRP1 FGF7	2.75e-05	178	88	5	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	normal_Lung-Myeloid_cells-CD163+CD14+_DCs\|normal_Lung / Location, Cell class and cell subclass	NR4A2 NR4A3 TASL AREG PRDM1	2.75e-05	178	88	5	b6dacaad09bf4384d0d4c926fbf769e74a8ec9a9
ToppCell	CD8+_Memory_T_cell-FLU-5\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	TCEA3 SPINT2 LAYN ZC3HAV1L SNAI1	2.83e-05	179	88	5	7f18dffa85285599662edbcd3f32ab42672bffb8
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TXNRD1 EMILIN2 NR4A3 EIF2AK4 TMEM9B	2.98e-05	181	88	5	c8286a7ac8e3cc5aa7e92b043a08435294ea686f
ToppCell	mild_COVID-19-NK_CD56bright\|World / disease group, cell group and cell class (v2)	SPAG1 ZNF600 NR4A2 NR4A3 AREG	3.14e-05	183	88	5	9a4899afac0f91203209392c5f67b3d0aa356b86
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 ADAMTS2 LRP1 FGF7 GFRA1	3.22e-05	184	88	5	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS2 NR4A2 EMILIN2 NR4A3 SNAI1	3.22e-05	184	88	5	d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCell	normal-na-Myeloid-conventional_dendritic_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	SPINT2 LAYN EMILIN2 EIF2AK4 AREG	3.31e-05	185	88	5	67e881a89a491665b8c612fff084c202c0c79235
ToppCell	Smart-seq2-spleen_(Smart-seq2)-lymphocytic-innate_lymphocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SYNE1 NR4A2 NR4A1 AREG PRDM1	3.40e-05	186	88	5	fc0b488c201a32d829047b58460297df2818b45d
ToppCell	NS-moderate-d_0-4-Myeloid-Non-resident_Macrophage\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ADAMTS2 EMILIN2 NR4A3 SNAI1 TASL	3.48e-05	187	88	5	fcc32dbc9c5ae6176f154715a3e73aa32d78ad64
ToppCell	3'_v3-blood-Myeloid_Dendritic-DC2\|blood / Manually curated celltypes from each tissue	SPINT2 MUC19 NR4A3 EIF2AK4 AREG	3.48e-05	187	88	5	9f3db9f0e5de34aeabfe5984f675bc7a65435df7
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 ADAMTS2 FGF7 NR4A3 GFRA1	3.48e-05	187	88	5	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_T_(gd)\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SPINT2 LAYN CTSA GFRA1 AREG	3.48e-05	187	88	5	e5713a7bda53d1d5178ab4e0dbadc2292b6005bc
ToppCell	Smart-seq2-spleen_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SYNE1 NR4A2 NR4A1 AREG PRDM1	3.48e-05	187	88	5	6981b856187a2e689260ecb7d0a1193a374ee9b9
ToppCell	3'_v3-blood-Myeloid_Dendritic-DC1\|blood / Manually curated celltypes from each tissue	SPINT2 EMILIN2 NR4A3 EIF2AK4 AREG	3.57e-05	188	88	5	411d4dd5c9dee7ebd8db352640cf009e7b033ba9
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	ADAMTSL1 LRP1 ZNF521 FGF7 GFRA1	3.57e-05	188	88	5	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ADAMTS2 EMILIN2 LRP1 TMEFF2	3.57e-05	188	88	5	7191087d8754f5e8700e3d744cd920ee26db1e57
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	NR4A2 NR4A3 SNAI1 NR4A1 PRDM1	3.57e-05	188	88	5	5d12afb483d028ca02b3b4215131f6128e8bcd48
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ADAMTS2 LRP1 FGF7 TMEFF2	3.66e-05	189	88	5	544d95df910f1b276995624509a7e41b219baca0
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	NR4A2 ZNF521 FGF7 NR4A3 NR4A1	3.66e-05	189	88	5	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNRD1 SPINT2 NR4A2 NR4A3 NR4A1	3.76e-05	190	88	5	92456f6f7eced6e4c4371f495254a65d061c8d0b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 ADAMTS2 SYNE1 FGF7 NUP153	3.76e-05	190	88	5	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	ADAMTSL1 ZNF521 FGF7 FRMPD3 GFRA1	3.76e-05	190	88	5	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	BAL-Control-Lymphocyte-B-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPAG1 NR4A2 ZNF724 NR4A3 NR4A1	3.76e-05	190	88	5	da7341a8a423e5fe4d8e733d8e50c10a3318ac1c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 ADAMTS2 SYNE1 FGF7 NUP153	3.76e-05	190	88	5	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPAG1 NR4A2 ZNF724 NR4A3 NR4A1	3.76e-05	190	88	5	42312f7d79fe889397d32910b625793e2535cc26
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPAG1 NR4A2 ZNF724 NR4A3 NR4A1	3.76e-05	190	88	5	682418a7a2096743112eae3790d40e7e600612c0
ToppCell	ILEUM\|World / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	NR4A2 NR4A3 NR4A1 AREG PRDM1	3.76e-05	190	88	5	4395dbd18c14d491f5066a2ddac438a16b1fd7c3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 ADAMTS2 LRP1 FGF7 GFRA1	3.85e-05	191	88	5	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SPINT2 NR4A2 NR4A3 NR4A1 AREG	3.85e-05	191	88	5	7bad04f8afa949ea952c5c0d71eec43271ade680
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 ADAMTS2 LRP1 FGF7 GFRA1	3.85e-05	191	88	5	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	droplet-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ADAMTS2 LRP1 FGF7 TMEFF2	3.95e-05	192	88	5	38d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 ADAMTS2 LRP1 FGF7 GFRA1	3.95e-05	192	88	5	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	SPAG1 EPPIN TMEM232 SYNE1 CFAP70	3.95e-05	192	88	5	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ADAMTS2 LRP1 FGF7 TMEFF2	3.95e-05	192	88	5	04d155897ed075c359933080e36a4ab2150b6e9f
ToppCell	ILEUM-non-inflamed-(2)_B_cell-(2)_Memory_B_cells\|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TCEA1 NR4A2 NR4A3 NR4A1 CTSA	3.95e-05	192	88	5	37d0d0fdd6bc3114d546020b472b6df9392392f4
ToppCell	356C-Myeloid-Dendritic-cDC2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SPINT2 NR4A2 NR4A3 NR4A1 TASL	3.95e-05	192	88	5	a7ccbea7c90c070d279d7ad3f2b5b7c0e3efd890
ToppCell	367C-Myeloid-Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NR4A2 NR4A3 SNAI1 NR4A1 AREG	3.95e-05	192	88	5	26326d7c3d907d754e85e128b7d8a52e90863f3f
Disease	Growth Deficiency and Mental Retardation with Facial Dysmorphism	SMC1A KMT2A	7.26e-06	2	80	2	C1854630
Disease	Myeloid Leukemia	SMC1A KMT2A KMT2E	1.52e-05	18	80	3	C0023470
Disease	Leukemia, Monocytic, Chronic	SMC1A KMT2A KMT2E	1.52e-05	18	80	3	C0023466
Disease	prostate cancer (is_marker_for)	KMT2A FGF7 PHF8 KMT2E TMEFF2	6.76e-05	156	80	5	DOID:10283 (is_marker_for)
Disease	Parkinsonism (biomarker_via_orthology)	NR4A2 GFRA1 GFRA2	1.08e-04	34	80	3	DOID:0080855 (biomarker_via_orthology)
Disease	Cornelia De Lange Syndrome	SMC1A KMT2A	2.01e-04	8	80	2	C0270972
Disease	Schizophrenia	NR4A2 ADNP2 LRP1 PLA2G1B KMT2A CTNND2 APOH LHX6 GFRA1	6.41e-04	883	80	9	C0036341
Disease	Autosomal recessive primary microcephaly	MFSD2A ZNF335	7.45e-04	15	80	2	cv:C3711387
Disease	migraine without aura, susceptibility to, 4	LRP1 GFRA1	8.50e-04	16	80	2	MONDO_0011847
Disease	Intellectual Disability	MFSD2A SYNE1 ZNF335 NR4A2 KMT2E ZBTB11	1.37e-03	447	80	6	C3714756
Disease	physical activity	ADAMTSL1 LIPG ZNF521	1.78e-03	88	80	3	EFO_0003940
Disease	partial thromboplastin time	APOH F11	1.93e-03	24	80	2	EFO_0004310
Disease	Neurodevelopmental Disorders	SMC1A KMT2A KMT2E	2.09e-03	93	80	3	C1535926
Disease	myocardial infarction (is_implicated_in)	LIPG LRP1 APOH	2.50e-03	99	80	3	DOID:5844 (is_implicated_in)
Disease	phospholipid measurement, intermediate density lipoprotein measurement	LIPG ZNF335 APOH	2.50e-03	99	80	3	EFO_0004639, EFO_0008595

Protein segments in the cluster

Peptide	Gene	Start	Entry
KKKNPCNAEFQNFCI	AREG	141	P15514
KNKEKKCSYTEDAQC	APOH	301	P02749
KVQNKLDGCCYAVKR	EIF2AK4	606	Q9P2K8
NCNKCIYFEAKKKQD	BRIX1	111	Q8TDN6
YGKANDDNKIALKNC	CTNND2	621	Q9UQB3
NKLCCKSCNLYNNLT	ADAMTS2	1086	O95450
YCKKCNANASSQDAL	ADNP2	216	Q6IQ32
EASNSNKKCKRYFNE	C17orf113	11	A0A1B0GUU1
NENFKKNVLSAVCYC	QRFPR	336	Q96P65
DVYCSQCCKKINLLN	RAB11FIP4	271	Q86YS3
QKNAKYICLANKDCP	NR4A1	296	P22736
KLNLAQKCFKNCYGE	NUB1	306	Q9Y5A7
CNMKNNFICKYSDEK	LAYN	176	Q6UX15
LKCSQKCDQNKFSVK	LRP1	1231	Q07954
YCEKVKQLKLCQLSQ	ADAMTSL1	1736	Q8N6G6
NRIYDSKKCCYTCKN	MUC19	8276	Q7Z5P9
VKANCSKDDFLFNCK	DDIAS	486	Q8IXT1
NDVSDLCKLENKQYC	DDIAS	601	Q8IXT1
GNCKYKVDCACLKEN	KMT2E	451	Q8IZD2
CRKNRCNSIGYNAKK	LIPG	311	Q9Y5X9
EYANCKKSQGNVDNK	MORF4L2	161	Q15014
QQNSCYIKNKEIFCK	LHX6	106	Q9UPM6
KKKQQLSVCNKLCYA	MFSD2A	36	Q8NA29
CSQNKCNFYDNKDLE	CTSA	241	P10619
KFLQNSAKKCAQDYN	ICE2	151	Q659A1
DAAKACNLDDICKKY	GFRA1	156	P56159
KACNLNDNCKKLRSS	GFRA2	166	O00451
EQKCQLSYELNCSGK	CFAP70	551	Q5T0N1
LNFYCDSCKAKLQEQ	FRMPD3	641	Q5JV73
KQCSHQISACNKDIY	F11	101	P03951
AKNCVFLDDKKVYCQ	KMT2A	1961	Q03164
KNSCEYKLTGLQQQC	EMILIN2	341	Q9BXX0
KLYAKKECNEDCNFK	FGF7	126	P21781
AEAKLKKNRCANCFD	DCTN4	61	Q9UJW0
TKNQRDCKLTCNYGN	SCUBE3	191	Q8IX30
LQKCVFSYNSNCQEK	CYP4F22	211	Q6NT55
NFQSKANCLNTCKNK	EPPIN	116	O95925
VQKNAKYVCLANKNC	NR4A2	291	P43354
QKNAKYVCLANKNCP	NR4A3	321	Q92570
ANAYHCEKCNKKVDT	USP9X	1766	Q93008
CKQLLQDEKAKCNKY	TAX1BP1	541	Q86VP1
KQCLKDKQALQDCAS	SYNE1	2501	Q8NF91
SYDNACQIKEASCQK	TMEFF2	201	Q9UIK5
NTARKQTCLDCKKNF	RFFL	56	Q8WZ73
LIKNCDSKSQKYNCL	SHLD2	431	Q86V20
DNCYDQAKKLDSCKF	PLA2G1B	71	P04054
LKKQNGKIKYECNVC	PRDM1	566	O75626
CKKKNCTYTQVQTRS	TCEA1	266	P23193
IGNKCQRCTNSEKKY	FAM76A	81	Q8TAV0
KCLQANSYMESKCQA	CMC4	16	P56277
RDNNKCYAKIICNTK	TXNRD1	566	Q16881
KDLQARKAFNCKYCN	SNAI1	146	O95863
KIHNAKKSYQCNECE	ZIM3	271	Q96PE6
KKSYQCNECEKSFRQ	ZIM3	276	Q96PE6
DNAVYKCVKCVNKYS	ZNF341	536	Q9BYN7
LKQVKDYIKQCSKCQ	ZBTB11	106	O95625
NCTACEKAFIYKNKL	ZNF549	586	Q6P9A3
KCKECGKAFNQCSNL	ZNF724	591	A8MTY0
KCNECGKVFNQKAYL	ZNF702P	91	Q9H963
IYNKNISQKDCDCLH	TMEM9B	56	Q9NQ34
SCKSICKNYNDLQIA	TASL	116	Q9HAI6
CHCKSSQKNILYLDK	TMEM232	386	C9JQI7
NNYLTKEECLKKCAT	SPINT2	76	O43291
KKAELIKGNYKCNVC	ZNF521	921	Q96K83
YKCQICNQSFRIKKT	ZBTB41	696	Q5SVQ8
NQCVNDKNYKDALSK	SPAG1	631	Q07617
KKALQYACGNALVCD	SMC1A	606	Q14683
DLFQCSKCKKKNCTY	TCEA3	306	O75764
SKCKKKNCTYNQVQT	TCEA3	311	O75764
NKVTDNKCIACQAAK	NUP153	671	P49790
YKCKECAKAFNQSSN	ZNF43	286	P17038
NNACDNIAKISKYKR	ZNF492	511	Q9P255
KPYKCNECAKAFNQS	ZNF852	241	Q6ZMS4
EKPYKCNDCEKAFNQ	ZNF879	481	B4DU55
KNKNKQLRNYCHSCN	XKR3	431	Q5GH77
KCKECGKAYNEASNL	ZNF98	211	A6NK75
CNNACDNIAKISKYK	ZNF98	551	A6NK75
ENNTCYAKIICNKFD	TXNRD3	561	Q86VQ6
YKCEKCVRAFNQASK	ZNF117	221	Q03924
CNKIGKAFNDKANCV	ZNF510	256	Q9Y2H8
LYCKLCKRQFTSKQN	ZNF800	486	Q2TB10
DQVDKCYKCSVKQGQ	PHF8	331	Q9UPP1
CGKCRKKNCTYTQVQ	TCEA2	261	Q15560
KLYKCNDCHKVFSNA	ZNF860	396	A6NHJ4
EKPYKCNECDKAFNQ	ZNF600	271	Q6ZNG1
QCSQCSFASKNKKDL	ZNF335	1076	Q9H4Z2
KQCKCDVCGKVFNQK	ZNF468	241	Q5VIY5
YQCKECKKAFSQIAH	ZNF583	296	Q96ND8
CGKNCSDEYKKINNV	ZMYM4	711	Q5VZL5
GTNKVYFKQLCCKCQ	ZAR1L	246	A6NP61
EYKCDVCGKIFNQKQ	ZNF816	256	Q0VGE8
YCNLKDKCNKFHVCK	ZC3HAV1L	181	Q96H79