Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

ERBB4 CAMKK1 POLE2 POLG GRK5 OBSCN CRPPA TERF1 CIT PXK SGK3 TGFBR3 PIK3C2G GUCY2C SHPK MAP3K9 PRKDC PAN3 PRKAG2

8.00e-0593815019GO:0016772
GeneOntologyMolecularFunctioncoumarin 7-hydroxylase activity

CYP2A7 CYP2A13

1.67e-0431502GO:0008389
GeneOntologyMolecularFunctionglycogen phosphorylase activity

PYGL PYGM

1.67e-0431502GO:0008184
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

ERBB4 CAMKK1 GRK5 OBSCN CIT PXK SGK3 TGFBR3 PIK3C2G GUCY2C SHPK MAP3K9 PRKDC PAN3 PRKAG2

2.98e-0470915015GO:0016773
GeneOntologyMolecularFunction5'-3' RNA exonuclease activity

DCP2 XRN1

3.33e-0441502GO:0004534
GeneOntologyMolecularFunctionAMP binding

PYGL PYGM PRKAG2

5.00e-04211503GO:0016208
GeneOntologyMolecularFunction1,4-alpha-oligoglucan phosphorylase activity

PYGL PYGM

5.52e-0451502GO:0004645
GeneOntologyMolecularFunctionnucleobase binding

DPYD PYGL

5.52e-0451502GO:0002054
GeneOntologyMolecularFunctionprotein kinase activity

ERBB4 CAMKK1 GRK5 OBSCN CIT PXK SGK3 TGFBR3 GUCY2C MAP3K9 PRKDC PAN3 PRKAG2

6.10e-0460015013GO:0004672
GeneOntologyMolecularFunctionkinase activity

ERBB4 CAMKK1 GRK5 OBSCN CIT PXK SGK3 TGFBR3 PIK3C2G GUCY2C SHPK MAP3K9 PRKDC PAN3 PRKAG2

6.48e-0476415015GO:0016301
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP2A7 CYP2A13 CYP2F1

7.49e-04241503GO:0008392
GeneOntologyMolecularFunctionglucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity

CHSY1 CSGALNACT1

8.24e-0461502GO:0047238
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

GLT8D1 UGGT1 CHSY1 COLGALT1 POMGNT2 CSGALNACT1

1.06e-031531506GO:0008194
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP2A7 CYP2A13 CYP2F1

1.06e-03271503GO:0008391
GeneOntologyMolecularFunctionhexosyltransferase activity

UGGT1 CHSY1 COLGALT1 POMGNT2 PYGL PYGM CSGALNACT1

1.10e-032111507GO:0016758
GeneOntologyMolecularFunctionexonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

POLG DCP2 XRN1 PAN3

1.22e-03621504GO:0016796
GeneOntologyMolecularFunction5'-deoxyribose-5-phosphate lyase activity

POLG XRCC6

1.52e-0381502GO:0051575
GeneOntologyMolecularFunctionglycosyltransferase activity

GLT8D1 UGGT1 CHSY1 COLGALT1 POMGNT2 PYGL PYGM CSGALNACT1

1.53e-032881508GO:0016757
GeneOntologyBiologicalProcessphenylpropanoid metabolic process

CYP2A7 CYP2A13 PON3

4.36e-05101503GO:0009698
GeneOntologyBiologicalProcesscoumarin metabolic process

CYP2A7 CYP2A13 PON3

4.36e-05101503GO:0009804
GeneOntologyBiologicalProcessmotile cilium assembly

DNHD1 DRC1 ARMC2 SPAG17 CFAP44 CFAP157

4.44e-05881506GO:0044458
GeneOntologyBiologicalProcesssperm flagellum assembly

DNHD1 DRC1 ARMC2 CFAP44 CFAP157

5.39e-05561505GO:0120316
GeneOntologyCellularComponentmotile cilium

DNHD1 SAXO2 DRC1 SSX9P SSX7 SSX5 ADGB SPAG17 CFAP44 PCNT

2.65e-0435515110GO:0031514
GeneOntologyCellularComponentstriated muscle myosin thick filament

MYOM1 OBSCN

3.08e-0441512GO:0005863
GeneOntologyCellularComponentDNA-dependent protein kinase complex

PRKDC XRCC6

5.11e-0451512GO:0070418
GeneOntologyCellularComponentDNA repair complex

RCOR1 PRKDC XRCC6

5.88e-04231513GO:1990391
MousePhenoshort sperm flagellum

DNHD1 DRC1 ARMC2 ADGB SPAG17 CFAP44

1.53e-05631196MP:0009239
DomainKRAB_RELATED

SSX9P SSX7 SSX2 SSX5

1.16e-06111474PS50806
DomainKrueppel-associated_box-rel

SSX9P SSX7 SSX2 SSX5

2.49e-06131474IPR003655
DomainSSX

SSX7 SSX2 SSX5

9.39e-0661473IPR028804
DomainSSXRD

SSX7 SSX2 SSX5

2.60e-0581473PF09514
DomainSSXRD_motif

SSX7 SSX2 SSX5

2.60e-0581473IPR019041
Domain-

GLT8D1 UGGT1 CHSY1 CRPPA COLGALT1 CSGALNACT1

4.29e-058114763.90.550.10
DomainNucleotide-diphossugar_trans

GLT8D1 UGGT1 CHSY1 CRPPA COLGALT1 CSGALNACT1

6.84e-05881476IPR029044
DomainZnF_C2HC

FAM90A14 FAM90A18 FAM90A9 FAM90A8 FAM90A10

7.15e-05551475SM00343
DomainZnf_CCHC

FAM90A14 FAM90A18 FAM90A9 FAM90A8 FAM90A10

7.15e-05551475IPR001878
DomainPHOSPHORYLASE

PYGL PYGM

1.84e-0431472PS00102
DomainGlycg_phsphrylas

PYGL PYGM

1.84e-0431472IPR011833
DomainGlyco_trans_35

PYGL PYGM

1.84e-0431472IPR000811
DomainPhosphorylase

PYGL PYGM

1.84e-0431472PF00343
DomainKinase-like_dom

ERBB4 CAMKK1 GRK5 OBSCN ACAD10 CIT PXK SGK3 PIK3C2G GUCY2C MAP3K9 PRKDC PAN3

3.61e-0454214713IPR011009
DomainCyt_P450_E_grp-I_CYP2A-like

CYP2A7 CYP2A13

3.65e-0441472IPR008067
DomainPID_Shc-like

SHC1 SHC3

3.65e-0441472IPR006019
DomainRho_GTPase_act

ARHGAP15 ARHGAP12

3.65e-0441472IPR015767
DomainPX

SNX16 PXK SGK3 PIK3C2G

3.92e-04441474SM00312
DomainPX

SNX16 PXK SGK3 PIK3C2G

5.93e-04491474PF00787
DomainPX

SNX16 PXK SGK3 PIK3C2G

6.40e-04501474PS50195
DomainPhox

SNX16 PXK SGK3 PIK3C2G

7.44e-04521474IPR001683
Pubmed

Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.

FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

7.11e-18251551017684299
Pubmed

Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.

FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A9 FAM90A8 FAM90A16 FAM90A10

4.25e-1623155918602769
Pubmed

Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.

FAM90A14 PPARG FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A9 FAM90A8 FAM90A10

5.77e-08164155922967998
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PDS5B NAA15 NOC2L PUF60 UGGT1 NSD1 BAZ2A XRN1 SMARCC2 PYGL LTA4H PRKDC UTRN XRCC6 PCNT

2.62e-076531551522586326
Pubmed

Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19.

CYP2A7 CYP2A13 CYP2F1

1.72e-06615538587134
Pubmed

The SSX gene family: characterization of 9 complete genes.

SSX9P SSX7 SSX2 SSX5

2.14e-0621155412216073
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

NAA15 PUF60 DLGAP5 ATG2B HNRNPM LARS1 HNRNPAB BAZ2A EIF4G2 XRN1 LTA4H PRKDC UTRN G6PD XRCC6 PCNT

4.73e-069341551633916271
Pubmed

Identification and characterization of mouse SSX genes: a multigene family on the X chromosome with restricted cancer/testis expression.

SSX9P SSX7 SSX5

7.15e-069155314611804
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

PDS5B NAA15 ARHGAP15 PUF60 LARS1 ETV5 HMMR PPARG CIT HNRNPAB RCOR1 EIF4G2 RBM5 SMARCC2 PYGL PRKDC XRCC6

9.41e-0611031551734189442
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

PDS5B NAA15 WASHC4 NOC2L DLGAP5 HNRNPM LARS1 COLGALT1 HNRNPAB BAZ2A RPTOR EIF4G2 XRN1 SMARCC2 PYGL PRKDC UTRN G6PD XRCC6

1.02e-0513531551929467282
Pubmed

USP22 regulates lipidome accumulation by stabilizing PPARγ in hepatocellular carcinoma.

HNRNPM PPARG PRKDC

1.40e-0511155335449157
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ATG2B SFMBT2 DENND4C RCOR1 SALL2 ZFHX4 XRN1 ZFHX3 UTRN PCNT

1.97e-054181551034709266
Pubmed

PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity.

PPARG RPTOR

1.97e-052155234004356
Pubmed

DNA-PKcs and Ku70 are predictive markers for poor prognosis of patients with gall bladder malignancies.

PRKDC XRCC6

1.97e-052155225046228
Pubmed

Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice.

CFTR PPARG

1.97e-052155220154695
Pubmed

A chondroitin synthase-1 (ChSy-1) missense mutation in a patient with neuropathy impairs the elongation of chondroitin sulfate chains initiated by chondroitin N-acetylgalactosaminyltransferase-1.

CHSY1 CSGALNACT1

1.97e-052155223811343
Pubmed

Expression of CYP2A genes in human liver and extrahepatic tissues.

CYP2A7 CYP2A13

1.97e-052155210353262
Pubmed

The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.

ZFHX4 ZFHX3

1.97e-052155210873665
Pubmed

Murine cell line SX9 bearing a mutation in the dna-pkcs gene exhibits aberrant V(D)J recombination not only in the coding joint but also in the signal joint.

PRKDC XRCC6

1.97e-05215529582343
Pubmed

Hepatitis C virus-core protein facilitates the degradation of Ku70 and reduces DNA-PK activity in hepatocytes.

PRKDC XRCC6

1.97e-052155219467273
Pubmed

Exome sequencing reveals NAA15 and PUF60 as candidate genes associated with intellectual disability.

NAA15 PUF60

1.97e-052155228990276
Pubmed

The vitamin B6-regulated enzymes PYGL and G6PD fuel NADPH oxidases to promote skin inflammation.

PYGL G6PD

1.97e-052155232126244
Pubmed

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

PRKDC XRCC6

1.97e-05215529390689
Pubmed

The role of alkaline phosphatase in intracellular lipid accumulation in the human hepatocarcinoma cell line, HepG2.

PPARG ALPL

1.97e-052155228209522
Pubmed

Expression of cancer-testis antigen (CTA) in tumor tissues and peripheral blood of Chinese patients with hepatocellular carcinoma.

SSX2 SSX5

1.97e-052155216546222
Pubmed

Molecular cloning and expression of a human chondroitin synthase.

CHSY1 CSGALNACT1

1.97e-052155211514575
Pubmed

Peroxisome proliferator-activated receptor gamma is required for regulatory CD4+ T cell-mediated protection against colitis.

PPARG PRKDC

1.97e-052155217312139
Pubmed

[A variety of functions of conventional and neuronal Shc adapter molecules in phosphotyrosine-mediated signalings].

SHC1 SHC3

1.97e-052155211831027
Pubmed

Novel GUCY2C variant causing familial diarrhea in a Mennonite kindred and a potential therapeutic approach.

CFTR GUCY2C

1.97e-052155233949097
Pubmed

Role of polymorphic XRCC6 (Ku70)/XRCC7 (DNA-PKcs) genes towards susceptibility and prognosis of lung cancer patients undergoing platinum based doublet chemotherapy.

PRKDC XRCC6

1.97e-052155229397516
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

DLGAP5 ATG2B FAM91A1 DENND4C KIDINS220 EIF4G2 XRN1 PRKDC

2.09e-05256155833397691
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

NAA15 PUF60 UGGT1 LARS1 COLGALT1 KIDINS220 PYGL PRKDC G6PD XRCC6

2.14e-054221551027342126
Pubmed

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.

PDS5B NAA15 NOC2L DLGAP5 RCOR1 XRN1 PYGM PRKDC

2.83e-05267155833417871
Pubmed

LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.

HNRNPM SHC1 SMARCC2 PRKDC XRCC6

2.85e-0579155526446488
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

CAND2 ARHGAP15 POLG UGGT1 DLGAP5 OBSCN NSD1 FAM91A1 COLGALT1 RCOR1 EIF4G2 MAP3K9 ITPRIP PAN3 UTRN PCNT

2.95e-0510841551611544199
Pubmed

Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse.

SAXO2 DRC1 ADGB PLET1 SPAG17

3.62e-0583155527914912
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DOC2A PUF60 POLG GRK5 OBSCN SHC1 NSD1 CHSY1 LAMC3 CIT ARHGEF10L PPP1R26 POMGNT2 RPTOR PRKDC PCNT

3.71e-0511051551635748872
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

NAA15 NOC2L PUF60 HNRNPM EIF4G2 PYGL LTA4H G6PD XRCC6 KLB

3.75e-054511551036168627
Pubmed

Localization of the muscle, liver, and brain glycogen phosphorylase genes on linkage maps of mouse chromosomes 19, 12, and 2, respectively.

ADA PYGL PYGM

3.80e-051515532575583
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

NOC2L HNRNPM CHSY1 FAM91A1 HNRNPAB FRY RCOR1 EIF4G2 XRN1 PAN3

4.59e-054621551031138677
Pubmed

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.

ARHGAP15 UGGT1 RPTOR PYGL LTA4H G6PD

4.59e-05143155630397336
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

NOC2L DLGAP5 HMMR CIT RCOR1 PRKDC PCNT

4.63e-05210155716565220
Pubmed

BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.

PUF60 ATG2B SHC1 FAM91A1 DENND4C EIF4G2 XRN1

5.53e-05216155731519766
Pubmed

Expression of cytochrome P450 2A5 in a glucose-6-phosphate dehydrogenase-deficient mouse model of oxidative stress.

CYP2A13 G6PD

5.90e-053155218068688
Pubmed

Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition.

CYP2A7 CYP2A13

5.90e-053155231645370
Pubmed

A role for DNA-PK in retroviral DNA integration.

PRKDC XRCC6

5.90e-053155210213687
Pubmed

Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86.

PRKDC XRCC6

5.90e-053155212604618
Pubmed

Association Between Functional Polymorphisms of DNA Double-Strand Breaks in Repair Genes XRCC5, XRCC6 and XRCC7 with the Risk of Systemic Lupus Erythematosus in South East Iran.

PRKDC XRCC6

5.90e-053155225756210
Pubmed

A trans-acting locus regulates transcriptional repression of the female-specific steroid 15 alpha-hydroxylase gene in male mice.

CYP2A7 CYP2A13

5.90e-05315528297477
Pubmed

Lack of the steroid 15 alpha-hydroxylase gene (Cyp2a-4) in wild mouse strain Mus spretus: rapid evolution of the P450 gene superfamily.

CYP2A7 CYP2A13

5.90e-05315528188299
Pubmed

DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner.

PRKDC XRCC6

5.90e-053155214627815
Pubmed

Soluble ecto-5'-nucleotidase (5'-NT), alkaline phosphatase, and adenosine deaminase (ADA1) activities in neonatal blood favor elevated extracellular adenosine.

ADA ALPL

5.90e-053155223897810
Pubmed

p107-Dependent recruitment of SWI/SNF to the alkaline phosphatase promoter during osteoblast differentiation.

RBL1 ALPL

5.90e-053155225182511
Pubmed

Comparison of hamster and mouse reveals interspecies differences in the regulation of hepatic CYP2A isozymes.

CYP2A7 CYP2A13

5.90e-05315528250953
Pubmed

Identification and characterization of a novel androgen receptor coregulator ARA267-alpha in prostate cancer cells.

NSD1 ETV5

5.90e-053155211509567
Pubmed

The structure and characterization of type I P-450(15) alpha gene as major steroid 15 alpha-hydroxylase and its comparison with type II P-450(15) alpha gene.

CYP2A7 CYP2A13

5.90e-05315522703500
Pubmed

Cryo-EM structure of human DNA-PK holoenzyme.

PRKDC XRCC6

5.90e-053155228840859
Pubmed

DNA-PK phosphorylation sites on Oct-1 promote cell survival following DNA damage.

PRKDC XRCC6

5.90e-053155217213819
Pubmed

ETV5 overexpression promotes progression of esophageal squamous cell carcinoma by upregulating SKA1 and TRPV2.

ETV5 TRPV2

5.90e-053155235813298
Pubmed

Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining.

PRKDC XRCC6

5.90e-053155210207111
Pubmed

Radioresistant cervical cancer shows upregulation of the NHEJ proteins DNA-PKcs, Ku70 and Ku86.

PRKDC XRCC6

5.90e-053155219672258
Pubmed

GlcUAβ1-3Galβ1-3Galβ1-4Xyl(2-O-phosphate) is the preferred substrate for chondroitin N-acetylgalactosaminyltransferase-1.

CHSY1 CSGALNACT1

5.90e-053155225568321
Pubmed

Evolution of Shc functions from nematode to human.

SHC1 SHC3

5.90e-053155211088019
Pubmed

Type III TGF-β receptor downregulation generates an immunotolerant tumor microenvironment.

TGFBR3 PRKDC

5.90e-053155223925295
Pubmed

Alteration of the substrate specificity of mouse 2A P450s by the identity of residue-209: steroid-binding site and orientation.

CYP2A7 CYP2A13

5.90e-053155222217847
Pubmed

RON Nuclear Translocation under Hypoxia Potentiates Chemoresistance to DNA Double-Strand Break-Inducing Anticancer Drugs.

PRKDC XRCC6

5.90e-053155226772202
Pubmed

The C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit.

PRKDC XRCC6

5.90e-053155210207052
Pubmed

Interaction of p53 and DNA-PK in response to nucleoside analogues: potential role as a sensor complex for DNA damage.

PRKDC XRCC6

5.90e-053155211751391
Pubmed

Defining interactions between DNA-PK and ligase IV/XRCC4.

PRKDC XRCC6

5.90e-053155212509254
Pubmed

Association between XRCC5, 6 and 7 gene polymorphisms and the risk of breast cancer: a HuGE review and meta-analysis.

PRKDC XRCC6

5.90e-053155223098447
Pubmed

Differential distribution of CYP2A6 and CYP2A13 in the human respiratory tract.

CYP2A7 CYP2A13

5.90e-053155222890016
Pubmed

ADAMTSL-3/punctin-2, a novel glycoprotein in extracellular matrix related to the ADAMTS family of metalloproteases.

ADAMTSL1 ADAMTSL3

5.90e-053155214667842
Pubmed

Catalytic subunit of DNA-dependent protein kinase: impact on lymphocyte development and tumorigenesis.

PRKDC XRCC6

5.90e-05315529990036
Pubmed

Microarray analysis identifies matrix metalloproteinases (MMPs) as key genes whose expression is up-regulated in human adipocytes by macrophage-conditioned medium.

MMP3 MMP19

5.90e-053155219585142
Pubmed

YES1 Kinase Mediates the Membrane Removal of Rescued F508del-CFTR in Airway Cells by Promoting MAPK Pathway Activation via SHC1.

CFTR SHC1

5.90e-053155237371529
Pubmed

DNA-dependent protein kinase phosphorylation sites in Ku 70/80 heterodimer.

PRKDC XRCC6

5.90e-053155210026262
Pubmed

DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis.

PRKDC XRCC6

5.90e-053155232103174
Pubmed

Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.

MYOM1 OBSCN

5.90e-053155227989621
Pubmed

The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells.

PRKDC XRCC6

5.90e-053155218710952
Pubmed

Synapsis of DNA ends by DNA-dependent protein kinase.

PRKDC XRCC6

5.90e-053155212065431
Pubmed

Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection.

PRKDC XRCC6

5.90e-053155211406603
Pubmed

Abnormal DNA-PKcs and Ku 70/80 expression may promote malignant pathological processes in gastric carcinoma.

PRKDC XRCC6

5.90e-053155224187467
Pubmed

Mapping of protein-protein interactions within the DNA-dependent protein kinase complex.

PRKDC XRCC6

5.90e-053155210446239
Pubmed

Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair.

PRKDC XRCC6

5.90e-053155224466051
Pubmed

The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation.

PRKDC XRCC6

5.90e-053155219664609
Pubmed

Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene.

CYP2A7 CYP2A13

5.90e-05315523346244
Pubmed

Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue.

CYP2A7 CYP2A13

5.90e-05315522733794
Pubmed

Metabolic Syndrome Mediates ROS-miR-193b-NFYA-Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction.

GUCY2C NFYA

5.90e-053155234157861
Pubmed

Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction.

CYP2A7 CYP2A13

5.90e-05315528484736
Pubmed

Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair.

PRKDC XRCC6

5.90e-053155216713581
Pubmed

Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions.

PRKDC XRCC6

5.90e-05315529362500
Pubmed

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen.

PRKDC XRCC6

5.90e-05315528422676
Pubmed

Tagging SNPs in non-homologous end-joining pathway genes and risk of glioma.

PRKDC XRCC6

5.90e-053155217389609
Pubmed

Cerium-induced strain-dependent increase in Cyp2a-4/5 (cytochrome P4502a-4/5) expression in the liver and kidneys of inbred mice.

CYP2A7 CYP2A13

5.90e-05315521417950
Pubmed

Impact of nicotine metabolism on nicotine's pharmacological effects and behavioral responses: insights from a Cyp2a(4/5)bgs-null mouse.

CYP2A7 CYP2A13

5.90e-053155224045421
Pubmed

The N-terminal region of the DNA-dependent protein kinase catalytic subunit is required for its DNA double-stranded break-mediated activation.

PRKDC XRCC6

5.90e-053155223322783
Pubmed

DNA-PK-dependent phosphorylation of Ku70/80 is not required for non-homologous end joining.

PRKDC XRCC6

5.90e-053155215941674
Pubmed

Highly homologous mouse Cyp2a4 and Cyp2a5 genes are differentially expressed in the liver and both express long non-coding antisense RNAs.

CYP2A7 CYP2A13

5.90e-053155232987105
Pubmed

Mouse steroid 15 alpha-hydroxylase gene family: identification of type II P-450(15)alpha as coumarin 7-hydroxylase.

CYP2A7 CYP2A13

5.90e-05315522765478
Pubmed

Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation.

CYP2A7 CYP2A13

5.90e-05315522415518
Cytoband8p23.1

FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

1.55e-10154156108p23.1
CytobandEnsembl 112 genes in cytogenetic band chr8p23

FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

8.93e-0923415610chr8p23
Cytoband14q21-q22

POLE2 PYGL

1.15e-052156214q21-q22
GeneFamilyGlycogen phosphorylases

PYGL PYGM

8.69e-053982437
GeneFamilyADAMTS like

ADAMTSL1 ADAMTSL3

6.00e-047982947
GeneFamilyCytochrome P450 family 2

CYP2A7 CYP2A13 CYP2F1

8.91e-04359831001
GeneFamilyLaminin subunits

LAMA3 LAMC3

1.85e-0312982626
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP15 ARHGAP6 ARHGAP12

2.52e-0350983721
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFHX4 ZFHX3

2.92e-0315982529
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

TERF1 RCOR1 SMARCC2

2.97e-0353983532
GeneFamilyBeta 4-glycosyltransferases

CHSY1 CSGALNACT1

3.75e-0317982425
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOC2A SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP157

1.43e-071781478de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellCiliated_cells-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DOC2A CYP2F1 SAXO2 CHST9 C1orf141 ADGB SPAG17 CFAP157

1.49e-0717914780e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ERBB4 ADAMTSL1 CFTR CIT SHC3 LIPH LTA4H FHIP1A

2.00e-0718614782ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)|390C / Donor, Lineage, Cell class and subclass (all cells)

DOC2A SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP157

2.00e-071861478708c5edefe36c91df27cf53c1b5101fb2030cc5a
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)-|390C / Donor, Lineage, Cell class and subclass (all cells)

DOC2A SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP157

2.00e-071861478029390c4aaf64e6bcd86124cd4a6dd2e6f3a374b
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOC2A SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP157

2.09e-07187147888f785932e67c613db0dda84496de351359ed962
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOC2A SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP157

2.09e-0718714788896a00b30d11b90ca42726d4e122174a30b161b
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SAXO2 DRC1 ADGB PLET1 SPAG17 CFAP44 CFAP157

2.26e-07189147802c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SAXO2 DRC1 ADGB PLET1 SPAG17 CFAP44 CFAP157

2.26e-071891478164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP2F1 SAXO2 DRC1 ADGB GOT1L1 SPAG17 CFAP44 CFAP157

2.26e-071891478fe958fdf9963c2dfe270f67f0da36b3264d0017c
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SAXO2 DRC1 ADGB PLET1 SPAG17 CFAP44 CFAP157

2.26e-071891478a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTSL1 CFTR LAMA3 PON3 ETV5 SHC3 FRY FHIP1A

2.36e-0719014788aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SAXO2 DRC1 ADGB SPAG17 CFAP44 LRRC36 CFAP157

2.36e-071901478088e3f39a1e5e11354d6e7458e8e6a39f14936b3
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SAXO2 DRC1 ADGB SPAG17 CFAP44 LRRC36 CFAP157

2.36e-07190147835248a8be476ea8d06d67c3d98a25be1f7c150b7
ToppCelldroplet-Lung-nan-18m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP2F1 CFTR ETV5 DRC1 GOT1L1 FAT2 SPAG17 CFAP157

2.36e-071901478b057bea6e55cef872290893b6e439bbcdcee2f2e
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SAXO2 DRC1 ADGB SPAG17 CFAP44 LRRC36 CFAP157

2.36e-0719014785f5206f9e725070d865f4c891ff08bb750e58582
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFTR LAMA3 PON3 ETV5 SHC3 PIK3C2G FHIP1A LRRC36

2.45e-07191147834cc997e4e5c727495f321e6807a84aa124da486
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ERBB4 ADAMTSL1 DLGAP5 LAMA3 CHST9 HMMR CIT MAP3K9

2.45e-07191147839220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

SAXO2 ARMC2 ZNF440 ADGB LIPH SPAG17 CFAP44 CFAP157

2.55e-0719214789cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP44 CFAP157

2.76e-071941478756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ERBB4 ADAMTSL1 DLGAP5 LAMA3 HMMR CIT MAP3K9 FHIP1A

2.76e-071941478c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ERBB4 ADAMTSL1 LAMA3 FRY PIK3C2G MAP3K9 FHIP1A LRRC36

2.76e-071941478c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ERBB4 ADAMTSL1 LAMA3 CHST9 FRY LIPH MAP3K9 FHIP1A

2.87e-071951478d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP44 CFAP157

2.87e-07195147834e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SAXO2 DRC1 ARMC2 ZNF440 ADGB SPAG17 CFAP44 CFAP157

2.87e-0719514783486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellPCW_10-12-Epithelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ERBB4 ADAMTSL1 LAMA3 FRY PIK3C2G MAP3K9 FHIP1A LRRC36

2.99e-0719614789bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ERBB4 ADAMTSL1 LAMA3 FRY PIK3C2G MAP3K9 FHIP1A LRRC36

2.99e-0719614787b17d47b7758d8ccf9dbefd097aeb553791a1eed
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SAXO2 DRC1 ARMC2 ZNF440 ADGB SPAG17 CFAP44 CFAP157

3.10e-07197147871fea4aa6ce96c7693fa94792d08770622873850
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOC2A SAXO2 ARMC2 ZNF440 ADGB SPAG17 CFAP44 CFAP157

3.10e-07197147874a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellPCW_13-14-Epithelial|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ERBB4 ADAMTSL1 LAMA3 FRY PIK3C2G MAP3K9 FHIP1A LRRC36

3.23e-07198147848eb6f69a464a34ab32e8d425a22b9d45ec20428
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB4 CFTR LAMA3 SHC3 LIPH FHIP1A LRRC36 ALPL

3.35e-071991478725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellBiopsy_Control_(H.)-Epithelial-Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP44 CFAP157

3.48e-0720014789ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCellBiopsy_Control_(H.)-Epithelial-Differentiating_Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

DOC2A CYP2F1 SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

3.48e-072001478a552a99f5e4fa00dfb7775e5a3e1f62f1530d104
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DOC2A SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP157

3.48e-0720014785abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DOC2A SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP157

3.48e-0720014789c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DOC2A SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP157

3.48e-072001478ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

DOC2A SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP157

3.48e-072001478a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DOC2A SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP157

3.48e-072001478918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

CYP2A13 DRC1 CHST9 ADGB SPAG17 FHIP1A CFAP157

7.17e-0715114778216462e723fec2797387929dde095370947e10a
ToppCell15-Distal-Epithelial-Multiciliated_precursor|Distal / Age, Tissue, Lineage and Cell class

DOC2A SAXO2 DRC1 C1orf141 ADGB SPAG17 CFAP157

1.41e-061671477442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCell15-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

SAXO2 DRC1 CHST9 C1orf141 ADGB SPAG17 CFAP157

1.52e-061691477425d89ab69e9f9eb3df84056676423e390cc6ab1
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SAXO2 ARMC2 ZNF440 ADGB SPAG17 CFAP44 CFAP157

1.52e-06169147714aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Deuterosomal|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DOC2A CYP2A13 DRC1 C1orf141 ADGB SPAG17 CFAP157

1.71e-06172147708ad76412c9cc3504141797b44b88478ced87476
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOC2A SAXO2 DRC1 ARMC2 SPAG17 CFAP44 CFAP157

1.78e-061731477c3762655caa79ac4879876f470d32578a3c93b01
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

CYP2A7 ERBB4 PON3 CIT SHC3 LIPH FHIP1A

2.00e-0617614773fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SAXO2 ADGB LIPH SPAG17 CFAP44 LRRC36 CFAP157

2.07e-061771477d947ba38db1772fc5fdcdc211f7511c4aa699dee
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SAXO2 ADGB LIPH SPAG17 CFAP44 LRRC36 CFAP157

2.07e-061771477d5640f0097878f0dac671e51dc51310278bb2682
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SAXO2 DRC1 CHST9 ZNF440 SPAG17 CFAP44 CFAP157

2.32e-0618014771f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellP03-Epithelial-airway_epithelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CYP2F1 SAXO2 DRC1 PLET1 SPAG17 CFAP44 CFAP157

2.41e-0618114771ea21d860d4d7abab3e21e130a16d044006656ee
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYOM1 LAMA3 FRY MYOZ1 TRPV2 ZFHX3 PLD5

2.41e-06181147759527ad218e49386b04cabb97d53d2ed55a35961
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 PPARG ARHGAP6 FRY PIK3C2G PRKAG2 SPAG17

2.41e-061811477aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellP03-Epithelial-airway_epithelial_cell-club_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CYP2F1 SAXO2 DRC1 PLET1 SPAG17 CFAP44 CFAP157

2.41e-06181147760a91587c59029a34e7bec1255083337fe21b72a
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

2.41e-061811477dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellP07-Epithelial-airway_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CYP2F1 SAXO2 DRC1 PLET1 SPAG17 CFAP44 CFAP157

2.68e-061841477a5e7af3392e9d6ddad0397f1eeb6b91ed1107cc2
ToppCellP07-Epithelial-airway_epithelial_cell-club_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CYP2F1 SAXO2 DRC1 PLET1 SPAG17 CFAP44 CFAP157

2.68e-061841477ab469b9e06212462cbe2e4db8775c6778db855e6
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

2.68e-0618414775daff849625f2f41d56615569c0ed59cd733b34c
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LAMA3 ETV5 CHST9 FRY MAP3K9 FHIP1A LRRC36

2.68e-061841477fa4915b0498f3069fd5ef497286445528f75187e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

ERBB4 CFTR PON3 CIT SHC3 LIPH FHIP1A

2.78e-061851477673f0c688ae6984bc8027df2da335787924f4137
ToppCell15-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

DOC2A SAXO2 DRC1 C1orf141 ADGB SPAG17 CFAP157

2.78e-0618514770998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

2.78e-0618514773e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

2.78e-06185147718a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellControl-Epithelial-ATII|World / Disease state, Lineage and Cell class

ERBB4 CFTR SHC3 LIPH FHIP1A LRRC36 ALPL

2.88e-061861477f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DOC2A SAXO2 CHST9 C1orf141 ADGB SPAG17 CFAP157

2.99e-0618714772b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DLGAP5 LAMA3 HMMR PIK3C2G MAP3K9 FHIP1A LRRC36

2.99e-061871477c2940aec30b3c2c113f6a65126dc6f1969cf301e
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

2.99e-061871477f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

2.99e-0618714779e10ed56090d82589bc457788282f664b70ace4b
ToppCelltumor_Lung-Epithelial_cells-tS3|tumor_Lung / Location, Cell class and cell subclass

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

3.09e-06188147726326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

3.09e-06188147761a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

3.09e-06188147734b11f72ca73153d02edcd09b38983ad1a504659
ToppCellCOPD-Epithelial-ATII|COPD / Disease state, Lineage and Cell class

ERBB4 CFTR ETV5 LIPH FHIP1A LRRC36 ALPL

3.09e-061881477eb6d79d733b53f64ca615bb777c64ed456866549
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SAXO2 DRC1 ADGB GOT1L1 SPAG17 CFAP44 CFAP157

3.09e-0618814770eca3dc93724e23b71e687fc24fa9f1e89bdef6a
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

3.09e-0618814772b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SAXO2 DRC1 ADGB GOT1L1 SPAG17 CFAP44 CFAP157

3.09e-0618814779ce3e1fffce87ad19812ecbf9b7f9935a975d676
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SAXO2 DRC1 ADGB SPAG17 CFAP44 CFAP157

3.20e-061891477057d7a03fdbe779122b203619a6f947f49b84d28
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

3.20e-061891477a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

3.20e-06189147768a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

3.20e-061891477dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellPND10-Epithelial-Epithelial_Airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SAXO2 DRC1 ADGB PLET1 SPAG17 CFAP44

3.20e-061891477407d8a59969d83f014600aae1a55092283a13970
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SAXO2 DRC1 ADGB SPAG17 CFAP44 CFAP157

3.20e-0618914779f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

3.20e-061891477b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

3.20e-06189147727329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

SAXO2 DRC1 ARMC2 ZNF440 ADGB SPAG17 CFAP44

3.20e-0618914773e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SAXO2 DRC1 ADGB SPAG17 CFAP44 CFAP157

3.20e-061891477e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCellCOPD-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

PADI4 ARHGAP15 GRK5 CHSY1 ADA SFMBT2 UTRN

3.32e-061901477ed978cd5d9da87b49878a330e362762c487f849f
ToppCellEpithelial_cells-Ciliated_cells-A|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

DOC2A CYP2F1 SAXO2 CHST9 ADGB SPAG17 CFAP157

3.32e-061901477549d813a8f23b175875e53347928941f143e236c
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA3 ETV5 CHST9 PIK3C2G MAP3K9 FHIP1A LRRC36

3.32e-061901477625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DOC2A SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP157

3.32e-061901477a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCellCiliated_cells-A|World / lung cells shred on cell class, cell subclass, sample id

DOC2A CYP2F1 SAXO2 CHST9 ADGB SPAG17 CFAP157

3.32e-061901477cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP2F1 CFTR ETV5 SAXO2 DRC1 SPAG17 CFAP44

3.32e-061901477edc0a0eb17abbecb0f06d302be3d4f8c1dd4f333
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

ERBB4 ADAMTSL1 CFTR LAMA3 SHC3 LIPH FHIP1A

3.43e-061911477d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ERBB4 CFTR LAMA3 SHC3 LIPH FHIP1A LRRC36

3.43e-061911477e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellwk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DOC2A SAXO2 DRC1 CHST9 SPAG17 CFAP44 CFAP157

3.43e-061911477e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCelldroplet-Lung-18m-Epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP2F1 CFTR ETV5 DRC1 SPAG17 CFAP44 CFAP157

3.43e-0619114771b59f1cad6c1a6a5938afa9195164918e3ff4e86
ToppCellLAM-Epithelial-AirwayEpi|LAM / Condition, Lineage and Cell class

CYP2F1 SAXO2 DRC1 CHST9 C1orf141 SPAG17 CFAP157

3.55e-0619214777404fc65be3b7bd09447725b43fa31819004dfee
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ERBB4 CFTR ETV5 SHC3 FHIP1A LRRC36 ALPL

3.55e-06192147758c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA3 ETV5 CHST9 PIK3C2G MAP3K9 FHIP1A LRRC36

3.55e-061921477b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFTR LAMA3 ETV5 SHC3 PIK3C2G FHIP1A LRRC36

3.55e-061921477fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SAXO2 DRC1 ADGB SPAG17 CFAP44 CFAP157

3.55e-0619214772d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ERBB4 ADAMTSL1 CFTR CHST9 FRY LIPH FHIP1A

3.68e-061931477b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

SAXO2 DRC1 CHST9 ADGB SPAG17 CFAP44 CFAP157

3.68e-061931477c0d10075862ac878aa05fc49c8b73e470783bf16
DrugAC1O3M08

DPYD PYGL PYGM

2.56e-0651463CID006331955
DrugL-BVAU

DPYD POLE2 POLG PYGL PYGM

4.28e-06381465CID000667554
Drug2,2-dimethyl-3-hydroxybutyric acid

CFTR PYGL PYGM

5.09e-0661463CID000152984
DrugEdUMP

DPYD PYGL PYGM

5.09e-0661463CID003085112
DrugAC1L3372

DPYD PYGL PYGM

8.87e-0671463CID000108025
DrugBrVarafUTP

POLE2 POLG PYGL PYGM

1.56e-05241464CID005273539
DrugPhosphonoserine

CFTR PYGL PYGM

2.11e-0591463DB04522
Drug2,6-dihydroxypyridine

DPYD PYGL PYGM

3.00e-05101463CID000069371
Drug19-hydroxytestosterone

CYP2A7 CYP2A13 CYP2F1 G6PD

3.91e-05301464CID000150968
Drug1-N-Acetyl-Beta-D-Glucosamine

PYGL PYGM

4.08e-0521462DB02320
Druggentamicin

UGGT1 CFTR CIT KIDINS220 GUCY2C PLCB2 UTRN G6PD

4.30e-051981468CID000003467
DrugTacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; MCF7; HT_HG-U133A

ETV5 LAMC3 FRY BAZ2A EIF4G2 MAP3K9 RBM5 UTRN

4.61e-0520014682633_UP
DrugAC1LCV0V

NSD1 ADA PYGL PYGM

5.07e-05321464CID000656468
DrugTCEO

CYP2A7 CYP2A13 CYP2F1 G6PD

6.48e-05341464CID000028167
DrugAC1O5XSP

CYP2A7 CYP2A13 CYP2F1 LTA4H

6.48e-05341464CID006442739
Drug8(9)-EET

CYP2A7 CYP2A13 CYP2F1 SHC1 LTA4H

8.18e-05691465CID000001901
DrugAC1MHTK1

ADA PYGL PYGM

8.93e-05141463CID003011158
DrugAC1Q69H9

DPYD PYGL PYGM

8.93e-05141463CID000001814
Drug11,14,15-THET

CYP2A7 CYP2A13 CYP2F1 LTA4H

1.12e-04391464CID006439531
Drugadenine

PDS5B POLE2 POLG NSD1 ETV5 ADA METTL1 RCOR1 GUCY2C PYGL PYGM G6PD

1.14e-0451014612CID000000190
Drug3,5-dimethylphenyl isocyanate

PYGL PYGM

1.22e-0431462CID000521488
Drugentadamide A

RBL1 LTA4H

1.22e-0431462CID006439215
Drug5'-deoxy-5'-fluoro-5'-(methylthio)adenosine

PYGL PYGM

1.22e-0431462CID000147839
DrugNSC758405

PYGL PYGM

1.22e-0431462CID000003201
Drug3,5-dinitrophenyl phosphate

PYGL PYGM

1.22e-0431462CID000151920
Drugpyridoxal phosphoglucose

PYGL PYGM

1.22e-0431462CID000196007
Druggamma-asarone

RBL1 LTA4H

1.22e-0431462CID000636750
Drug5-ethyl-4-hydroxy-2-methyl-3(2H)-furanone

PYGL PYGM

1.22e-0431462CID000093111
Drugadenosine-5'-chloromethylphosphonate

PYGL PYGM

1.22e-0431462CID000191554
Drugxanthoxylol

RBL1 LTA4H

1.22e-0431462CID000130679
Drughydan

PYGL PYGM

1.22e-0431462CID000008360
DrugEHMF

PYGL PYGM

1.22e-0431462CID000033931
Drugpyridoxal 5'-methylenephosphonate

PYGL PYGM

1.22e-0431462CID003082249
DrugPlp 5'-mpa

PYGL PYGM

1.22e-0431462CID003082151
Drugglucose-1,2-cyclic phosphate

PYGL PYGM

1.22e-0431462CID000191723
Drug2'-methoxyacetophenone

CYP2A7 CYP2A13

1.22e-0431462CID000068481
Drugentadamide B

RBL1 LTA4H

1.22e-0431462CID003035981
Drug3'-FFdUrd

PYGL PYGM

1.22e-0431462CID000072260
Drug2',3',4',5,5'-pentachloro-2-biphenylol

PYGL PYGM

1.22e-0431462CID000119518
DrugAC1L8XK3

PYGL PYGM

1.22e-0431462CID000409735
DrugN-acetyl-N'-beta-D-glucopyranosyl urea

PYGL PYGM

1.22e-0431462CID000446801
Drugriboflavin tetraacetate

PYGL PYGM

1.22e-0431462CID000094186
Drug2,5-dimethyl-3-furanone

PYGL PYGM

1.22e-0431462CID000085730
Drug3,5-dinitrophenol

PYGL PYGM

1.22e-0431462CID000011459
DrughilE

LARS1 ACAD10 CIT PYGL PYGM

1.30e-04761465CID000000791
Diseasepolycythemia due to hypoxia (implicated_via_orthology)

SNX16 PXK

2.20e-0521392DOID:2835 (implicated_via_orthology)
Diseasepulse pressure measurement

GLT8D1 SYNPO2L ACAD10 PPARG ADAMTSL3 DENND4C FBXO38 TGFBR3 ZFHX4 RPTOR ARHGAP12 TRIM8 ZFHX3 PRKAG2 FAM118A XRCC6 KLB

3.05e-04139213917EFO_0005763
DiseaseThyroid cancer, follicular

MINPP1 PPARG

4.56e-0471392C2931367
Diseaseurate measurement, bone density

ERBB4 ARHGAP15 MINPP1 SHC3 SFMBT2 SALL2 KIDINS220 EIF4G2 PRKDC UTRN

7.27e-0461913910EFO_0003923, EFO_0004531
Diseaseglycogen storage disease (is_implicated_in)

PYGL PRKAG2

7.76e-0491392DOID:2747 (is_implicated_in)
DiseaseParoxysmal atrial fibrillation

ERBB4 CAND2 SYNPO2L MYOZ1 ZFHX3

8.82e-041561395C0235480
Diseasefamilial atrial fibrillation

ERBB4 CAND2 SYNPO2L MYOZ1 ZFHX3

8.82e-041561395C3468561
DiseasePersistent atrial fibrillation

ERBB4 CAND2 SYNPO2L MYOZ1 ZFHX3

8.82e-041561395C2585653
Diseaseabdominal obesity-metabolic syndrome (implicated_via_orthology)

PPARG GUCY2C

9.67e-04101392DOID:0060611 (implicated_via_orthology)
DiseaseAtrial Fibrillation

ERBB4 CAND2 SYNPO2L MYOZ1 ZFHX3

9.87e-041601395C0004238
Diseaseglomerulosclerosis (implicated_via_orthology)

SHC1 PPARG

1.18e-03111392DOID:0050851 (implicated_via_orthology)
Diseasepeanut allergy measurement, parental genotype effect measurement

ADGB FAM118A

1.18e-03111392EFO_0005939, EFO_0007017
DiseaseMale sterility

POLG CFTR TDRD7

1.52e-03481393C0917731
DiseaseMale infertility

POLG CFTR TDRD7

1.52e-03481393C0021364
DiseaseSubfertility, Male

POLG CFTR TDRD7

1.52e-03481393C0848676
DiseaseHepatic fibrosis

CYP2A13 ERBB4 CYP2F1

1.61e-03491393HP_0001395
Diseasemammographic density measurement

PPARG ADAMTSL3 SPAG17

1.71e-03501393EFO_0005941
Diseasesitting height ratio

NSD1 CRPPA ADAMTSL3

1.81e-03511393EFO_0007118
Diseaseheart failure

ADAMTSL1 HLF SYNPO2L ACAD10 ZFHX3

1.87e-031851395EFO_0003144
DiseaseMUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K

CRPPA POMGNT2

1.93e-03141392C1836373
Diseasealpha-Dystroglycanopathies

CRPPA POMGNT2

1.93e-03141392C2936406
DiseaseFukuyama Type Congenital Muscular Dystrophy

CRPPA POMGNT2

1.93e-03141392C0410174
Diseasetriacylglycerol 48:4 measurement

SFMBT2 PLD5

1.93e-03141392EFO_0010407
DiseaseMuscle eye brain disease

CRPPA POMGNT2

1.93e-03141392C0457133
DiseaseMuscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 1

CRPPA POMGNT2

1.93e-03141392C4284790
DiseaseMetastatic melanoma

GUCY2C MAP3K9 PRKDC

2.13e-03541393C0278883
DiseaseWalker-Warburg congenital muscular dystrophy

CRPPA POMGNT2

2.22e-03151392C0265221
DiseaseHOMA-B

CAND2 CRPPA TGFBR3

2.24e-03551393EFO_0004469
DiseaseHypertrophic Cardiomyopathy

MYOM1 OBSCN PRKAG2

2.49e-03571393C0007194
Disease2-hydroxyglutarate measurement

PLD5 PCNT

2.53e-03161392EFO_0021506
DiseaseAmyotrophic Lateral Sclerosis

ERBB4 GLT8D1 PON3

2.61e-03581393C0002736
Diseasecranial vault morphology measurement

ADAMTSL1 LAMA3 ADAMTSL3 SFMBT2

2.62e-031211394EFO_0009278
Diseaselifestyle measurement, maximum cigarettes per day measurement

ADAMTSL1 ARHGAP15 ARHGEF10L TDRD7

2.70e-031221394EFO_0009264, EFO_0010724
Diseasefatty liver disease (is_marker_for)

SHC1 ALPL

2.86e-03171392DOID:9452 (is_marker_for)
Diseaseposterior cingulate cortex volume measurement

CHST9 PYGL

2.86e-03171392EFO_0010324
Diseasememory performance

PDS5B DPYD GLT8D1 NOC2L PPARG ARMC2 PRKAG2

3.33e-034091397EFO_0004874
Diseaseprostate carcinoma

ADAMTSL1 NSD1 CHSY1 ARMC2 ARHGAP6 RCOR1 GUCY2C TRIM8 ZFHX3 FAM118A CFAP44

3.37e-0389113911EFO_0001663
DiseaseTinnitus

CAMKK1 DCP2 RCOR1 MTCH1

3.39e-031301394HP_0000360
Diseasetransient cerebral ischemia (implicated_via_orthology)

PPARG HNRNPAB G6PD

3.46e-03641393DOID:224 (implicated_via_orthology)
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

ERBB4 ADA

3.57e-03191392DOID:2876 (is_marker_for)
Diseasefamilial hyperlipidemia (biomarker_via_orthology)

SHC1 ADA

3.57e-03191392DOID:1168 (biomarker_via_orthology)
Diseaserenovascular hypertension (biomarker_via_orthology)

EIF4G2 G6PD

3.57e-03191392DOID:1591 (biomarker_via_orthology)
Diseaseobesity (implicated_via_orthology)

ETV5 ZFHX4 GUCY2C ZFHX3 PLCB2

3.58e-032151395DOID:9970 (implicated_via_orthology)
Diseasetuberculosis

RBL1 POLG LAMA3 SALL2 PLD5

3.65e-032161395MONDO_0018076
Diseasebitter alcoholic beverage consumption measurement

CPNE8 ARHGAP15 ZFHX3 KLB

3.67e-031331394EFO_0010092
DiseaseSevere Combined Immunodeficiency

ADA PRKDC

3.96e-03201392C0085110
Diseaseatypical femoral fracture, response to bisphosphonate

CPNE8 TDRD7 MTCH1

4.10e-03681393EFO_0009958, EFO_0009960
Diseasefacial height measurement

GRK5 TERF1 LIPH PLD5

4.64e-031421394EFO_0007856

Protein segments in the cluster

PeptideGeneStartEntry
DRMKLPSPNDSKFFQ

ERBB4

991

Q15303
PKPAFMKQNLDELGI

PRKAG2

416

Q9UGJ0
GMDKPLTLPDFLAKF

ADA

51

P00813
KPDKSGRPISFMVVF

ARHGEF10L

721

Q9HCE6
KFERMFSAGKPTSIP

C1orf141

346

Q5JVX7
SRVFKFIDMPTEGKP

CFTR

1161

P13569
LFRPFGPIMKVKNEK

CSGALNACT1

241

Q8TDX6
TKPPPNFKFAFRAMV

ADGB

856

Q8N7X0
SMIKSKQIFPFFDIP

GOT1L1

201

Q8NHS2
RRGRPPSKFFKQMEQ

BAZ2A

1406

Q9UIF9
DKMLGKLDPFYQPSV

ARMC2

6

Q8NEN0
MKFPGPLENQRLSFL

CCNI

1

Q14094
GFRVFKEMPFTNPLT

ACAD10

601

Q6JQN1
PRIAELMDKKLPSFG

DPYD

866

Q12882
APNLFGTPRDKAEMF

POLE2

116

P56282
SKLGLAPNKFFMAIP

DCP2

216

Q8IU60
KDEFLMPKFQGQPSD

DNHD1

621

Q96M86
PEMRAPGSLKRLEKF

CFAP157

496

Q5JU67
MGDFNLKTAPDYKIP

CFAP44

1171

Q96MT7
MNFQRFLKFPDDPKV

CIT

316

O14578
DPQRKALLHMFSGKP

FAM90A10

111

A6NDY2
TPNKADMKPGAFQRR

ATG2B

1371

Q96BY7
RKPPKGMFLSQEDVE

RCOR1

311

Q9UKL0
LPDPGKAQDFMKKFT

PDS5B

536

Q9NTI5
KLLESNDLDPGFMPK

NSD1

1411

Q96L73
KKSPAFMPFSAGRRL

CYP2F1

421

P24903
TKKPGMFFNPEESEL

G6PD

406

P11413
ENSNGMKPFRPDLFL

GUCY2C

696

P25092
IKFRSGKFMPFNLIP

ITPRIP

336

Q8IWB1
PLFPKEKSILGSMLF

PIK3C2G

581

O75747
FLDFKLVPPSQKMEN

CRPPA

376

A4D126
EQGRMKFTRPLFKDL

LTA4H

561

P09960
LKEFPIKRVMGPDFG

PADI4

376

Q9UM07
DPQRKALLHMFSGKP

FAM90A23

111

A8MXZ1
PKPDDGRKSFLMKRG

KIDINS220

1441

Q9ULH0
KPPFLMLLKGSTRFN

LAMA3

2931

Q16787
KSMLRKRSFGNPFEP

CAMKK1

451

Q8N5S9
ADMGVPLPAKNLIFK

FAM91A1

801

Q658Y4
VKMDERALPKGDFFP

HNRNPM

276

P52272
FDEKRNSMEPGFPKQ

MMP3

411

P08254
FQKFPDKEILRMAGP

ADAMTSL1

256

Q8N6G6
DPQRKALLHMFSGKP

FAM90A22

111

A8MWA6
DPQRKALLHMFSGKP

FAM90A14

111

P0C7W9
EPEALKFFKIDPSMG

FAT2

1806

Q9NYQ8
SDILFPKMPKRQGDF

KIAA1586

61

Q9HCI6
PKMPKRQGDFLHFLN

KIAA1586

66

Q9HCI6
EMDSNKGLFIPFPNR

LRRC36

191

Q1X8D7
INFKMSPGFPKKLNR

MMP19

361

Q99542
NVGSPFAKDFLPKME

POLG

761

P54098
LQPFADAMKLFTKEP

MT-ND1

46

P03886
PDQGESMKPLTFARF

GLT8D1

141

Q68CQ7
SMAFPDNQRPFLKAE

ETV5

456

P41161
LRGKDPPMTKAFFDT

LIPH

306

Q8WWY8
NFVELPAAALRFMPK

POMGNT2

131

Q8NAT1
DPQRKALLHMFSGKP

FAM90A17

111

P0DV74
SIPGQEMFDPRKRKF

HLF

186

Q16534
DPMLSPDFQPKSAFK

RBM12B-AS1

46

Q9P1G2
DPQRKALLHMFSGKP

FAM90A16

111

P0DV73
DMPPRFSKKGQLNAD

EIF4G2

456

P78344
VDFNRKPGRMSSKPI

NOC2L

486

Q9Y3T9
ISGRFQPLPEAMKEK

PCNT

2371

O95613
FEGPQPADVRLMKRK

RBM5

121

P52756
AFVMGLKKPRDSRAP

DRC1

631

Q96MC2
DPQRKALLHMFSGKP

FAM90A19

111

P0DV76
DKFLRMNFSKGCPPV

NAA15

311

Q9BXJ9
ITGALKMFFRELPEP

ARHGAP12

726

Q8IWW6
EFMIFRKVPKSAQPE

OBSCN

7321

Q5VST9
KDKEFIPQAFGMPLS

ARHGAP6

271

O43182
MSFPKAPLKRFNDPS

HMMR

1

O75330
FGLAPMLSDTDKKPF

ALPL

396

P05186
KFGDKSLFQPQPNEM

PRICKLE1

421

Q96MT3
PKANAPSFFMADELR

PAN3

436

Q58A45
DPQRKALLHMFSGKP

FAM90A8

111

A6NJQ4
EFISLDQMFREPPKG

FBXO38

456

Q6PIJ6
RKMSPRTGDAKPSFF

FAM118A

96

Q9NWS6
LRMKGFLAQTPPLEF

ZNF561-AS1

56

K7EIQ3
RNPMLAAALFPEFLK

FHIP1A

1001

Q05DH4
RDFFLPKGTEVFPML

CYP2A13

381

Q16696
LKPMDFNGLADPYVK

DOC2A

116

Q14183
RDFFLPKGTEVFPML

CYP2A7

381

P20853
SFAPKDFMFQPLDGL

DLGAP5

306

Q15398
EVPFPRGMKGQDFEK

DENND4C

1451

Q5VZ89
FSPQKMPLSKELGFS

GPR156

581

Q8NFN8
PEGMRKKLFSVLPIF

KLB

341

Q86Z14
AKAFMPRGLADKQGP

CXorf38

116

Q8TB03
SFLKDYDPMGNKKEP

C2orf50

91

Q96LR7
VGKPAKAFSLNPERM

FRY

481

Q5TBA9
DPQRKALLHMFSGKP

FAM90A20P

111

A6NIJ5
RFISAPTKTPDKMGF

COLGALT1

326

Q8NBJ5
MNFKRLEAGMLDPPF

GRK5

451

P34947
AFEAFLRKCPKEMGP

CAND2

281

O75155
DPQRKALLHMFSGKP

FAM90A5P

111

A8MXJ8
TAPGLPAFNKFVLMK

SALL2

501

Q9Y467
PAMALKIPAKRIFGD

SGK3

66

Q96BR1
SDKMFPALGFGAKLP

CPNE8

356

Q86YQ8
FKKEEPMLLLGDPSA

MAP3K9

816

P80192
DPQRKALLHMFSGKP

FAM90A24P

111

P0C7X0
GRFFSPKEKDSPHMQ

NFYA

316

P23511
VKEKLSNFLPDLPGM

MED19

101

A0JLT2
GSETNEFKFLKPIMP

PCDHB6

756

Q9Y5E3
RGSMKKVFPPDEIEQ

MTCH1

166

Q9NZJ7
PRATPKQGIKALDFM

SYNPO2L

836

Q9H987
PPINDMFTDLKDGRK

UTRN

51

P46939
PMDPKLNKRRGFVFI

HNRNPAB

186

Q99729
GFEQMRLKSRPKEPS

PLD5

16

Q8N7P1
RQAFAPFGPIKSIDM

PUF60

146

Q9UHX1
AKRRLFGEDPPKEML

RBL1

656

P28749
SKVKLMRFDDPLLGP

LARS1

1111

Q9P2J5
DPQRKALLHMFSGKP

FAM90A12P

111

A8MX19
DPQRKALLHMFSGKP

FAM90A9

111

A6NNJ1
DPQRKALLHMFSGKP

FAM90A13P

111

P0C7W8
DLATFQGDKMPPFQK

GCM2

246

O75603
LKSLRKPFGDFMEPK

PPARG

381

P37231
VTGALKMFFRELPEP

ARHGAP15

351

Q53QZ3
FDMKPFEDALKNQPL

SHC3

451

Q92529
KQEVQRAFPLPMSFG

SHPK

441

Q9UHJ6
FESLSKFNVKFPPMD

TANK

226

Q92844
EFAFRKPPRLAKMNV

PPP1R26

286

Q5T8A7
MPFFLEGKPKATLRQ

TDRD7

111

Q8NHU6
LPKKRGTFIEFRNGM

PMM1

121

Q92871
FPDKGKEKPTDMQNF

SMARCC2

561

Q8TAQ2
DPQRKALLHMFSGKP

FAM90A15P

111

P0C7V4
HQFPRTRKMFDKGPE

RPTOR

921

Q8N122
MDIKNRIIPPFFKSE

SPAG17

1901

Q6Q759
KEDLQLGIPPSFMRF

CHSY1

351

Q86X52
LQMIGAPKELKFPNF

CHST9

381

Q7L1S5
KPFFMITPKSIRLEG

PLET1

166

Q6UQ28
FLPFADDKRKMPFTE

XRCC6

436

P12956
VGNPSDLPRTFEFMK

ZNF440

576

Q8IYI8
LPFRKGPNFTMEKFL

ZFHX4

1476

Q86UP3
ESGMPKERFSAEFPK

TRBV18

76

A0A087X0M5
MAAGEPRSLLFFQKP

ZFP57

1

Q9NU63
FGPPTVNDKLMRFFD

MINPP1

216

Q9UNW1
FSPKQPDLFKDIVNM

PYGM

751

P11217
EAMTKLGFKATLPPF

SSX2

56

Q16385
LGFKATLPPFMCNKR

SSX2

61

Q16385
EAMTKLGFKATLPPF

SSX5

56

O60225
LGFKATLPPFMRNKR

SSX5

61

O60225
EAMTKLGFKATLPPF

SSX7

56

Q7RTT5
EAMTKLGFKATLPPF

SSX9P

56

Q7RTT3
FSDVPFLTGQKMLPK

SPATA31D1

1551

Q6ZQQ2
LIDAAKFPLPMEVFK

SFMBT2

276

Q5VUG0
LPPMESQFQGEDRKF

TRPV2

36

Q9Y5S1
KPRKVFFMAVDGVAP

XRN1

76

Q8IZH2
PPKKLIGNMDREFIA

PXK

76

Q7Z7A4
NFAPDEPGKIFLMDL

PON3

76

Q15166
FGDPNSHMPFKSKLL

TERF1

201

P54274
AALFMKVGKNFPPAE

SGSM1

71

Q2NKQ1
PKSQKLRDVFNMDFP

PLCB2

76

Q00722
NFPFQGKSIMKEDFP

SAXO2

276

Q658L1
KVTKSFPPLADRFMN

PRKDC

2366

P78527
SDLKPKMRRPAGELF

nan

166

Q8IYB0
KMRRPAGELFSPKDA

nan

171

Q8IYB0
MNALDGVPFKLPKGF

UBAP1L

1

F5GYI3
DRNPFKVGMKDLALF

WASHC4

696

Q2M389
LNDKLKEMFPGFRLA

SNX16

151

P57768
EKQLRKMLEGPFSTP

TRIM8

341

Q9BZR9
FSPKQPDLFKDIINM

PYGL

751

P06737
NGSAPRDLFDMKPFE

SHC1

451

P29353
KGQLTKMFFLFPDPH

METTL1

151

Q9UBP6
NSFAKGPIAKFLDMP

UGGT1

1051

Q9NYU2
FPIPQADMDKKRFSF

TGFBR3

676

Q03167
ERDFPSGLMIFKKSP

ZFP3

66

Q96NJ6
PFRKGPNFTMEKFLD

ZFHX3

1526

Q15911
TFKIPGPLMADFIFK

ADAMTSL3

306

P82987
DPQRKALLHMFSGKP

FAM90A18

111

P0DV75
KFQKGMPPRILLNTD

LEG1

261

Q6P5S2
DLEGMKLQFPRPKDQ

LAMC3

1341

Q9Y6N6
PTPNDKGKYVMELFD

MYOM1

1521

P52179
KRMTFQMPKFDLGPL

MYOZ1

236

Q9NP98