| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyBiologicalProcess | regulation of heme biosynthetic process | 8.64e-07 | 9 | 46 | 3 | GO:0070453 | |
| GeneOntologyBiologicalProcess | regulation of tetrapyrrole biosynthetic process | 8.64e-07 | 9 | 46 | 3 | GO:1901463 | |
| GeneOntologyBiologicalProcess | regulation of tetrapyrrole metabolic process | 1.23e-06 | 10 | 46 | 3 | GO:1901401 | |
| GeneOntologyBiologicalProcess | heme biosynthetic process | 5.92e-05 | 34 | 46 | 3 | GO:0006783 | |
| GeneOntologyBiologicalProcess | positive regulation of ATPase-coupled calcium transmembrane transporter activity | 7.26e-05 | 6 | 46 | 2 | GO:1901896 | |
| GeneOntologyBiologicalProcess | porphyrin-containing compound biosynthetic process | 8.97e-05 | 39 | 46 | 3 | GO:0006779 | |
| GeneOntologyBiologicalProcess | tetrapyrrole biosynthetic process | 8.97e-05 | 39 | 46 | 3 | GO:0033014 | |
| GeneOntologyBiologicalProcess | anatomical structure maturation | 1.29e-04 | 354 | 46 | 6 | GO:0071695 | |
| GeneOntologyBiologicalProcess | heme metabolic process | 2.38e-04 | 54 | 46 | 3 | GO:0042168 | |
| GeneOntologyBiologicalProcess | small molecule catabolic process | 3.28e-04 | 421 | 46 | 6 | GO:0044282 | |
| GeneOntologyBiologicalProcess | organic acid catabolic process | 3.39e-04 | 272 | 46 | 5 | GO:0016054 | |
| GeneOntologyBiologicalProcess | carboxylic acid catabolic process | 3.39e-04 | 272 | 46 | 5 | GO:0046395 | |
| GeneOntologyBiologicalProcess | regulation of ATPase-coupled calcium transmembrane transporter activity | 3.74e-04 | 13 | 46 | 2 | GO:1901894 | |
| GeneOntologyBiologicalProcess | porphyrin-containing compound metabolic process | 3.75e-04 | 63 | 46 | 3 | GO:0006778 | |
| GeneOntologyBiologicalProcess | pigment biosynthetic process | 3.75e-04 | 63 | 46 | 3 | GO:0046148 | |
| GeneOntologyBiologicalProcess | skeletal system development | 3.94e-04 | 615 | 46 | 7 | GO:0001501 | |
| GeneOntologyBiologicalProcess | developmental maturation | 4.09e-04 | 439 | 46 | 6 | GO:0021700 | |
| GeneOntologyBiologicalProcess | tetrapyrrole metabolic process | 5.79e-04 | 73 | 46 | 3 | GO:0033013 | |
| GeneOntologyCellularComponent | calcium channel complex | 2.18e-05 | 73 | 47 | 4 | GO:0034704 | |
| GeneOntologyCellularComponent | transporter complex | 2.78e-05 | 550 | 47 | 8 | GO:1990351 | |
| GeneOntologyCellularComponent | sarcoplasmic reticulum membrane | 1.41e-04 | 45 | 47 | 3 | GO:0033017 | |
| GeneOntologyCellularComponent | transmembrane transporter complex | 1.56e-04 | 523 | 47 | 7 | GO:1902495 | |
| GeneOntologyCellularComponent | monoatomic ion channel complex | 1.93e-04 | 378 | 47 | 6 | GO:0034702 | |
| GeneOntologyCellularComponent | sarcoplasmic reticulum | 1.02e-03 | 88 | 47 | 3 | GO:0016529 | |
| GeneOntologyCellularComponent | organelle envelope | TMEM14C TYMS TMEM120A TMEM14DP DMPK BCL2L10 RYR2 EBP TMEM14B ETFDH | 1.12e-03 | 1435 | 47 | 10 | GO:0031967 |
| GeneOntologyCellularComponent | cation channel complex | 1.90e-03 | 235 | 47 | 4 | GO:0034703 | |
| GeneOntologyCellularComponent | sarcoplasm | 2.15e-03 | 114 | 47 | 3 | GO:0016528 | |
| MousePheno | decreased cellular hemoglobin content | 2.19e-06 | 10 | 38 | 3 | MP:0008956 | |
| MousePheno | abnormal cellular hemoglobin content | 4.01e-06 | 12 | 38 | 3 | MP:0008954 | |
| Domain | TMEM14 | 1.39e-07 | 5 | 46 | 3 | IPR005349 | |
| Domain | Tmemb_14 | 1.39e-07 | 5 | 46 | 3 | PF03647 | |
| Domain | MIR | 2.64e-04 | 10 | 46 | 2 | PS50919 | |
| Domain | MIR | 2.64e-04 | 10 | 46 | 2 | PF02815 | |
| Domain | MIR | 2.64e-04 | 10 | 46 | 2 | SM00472 | |
| Domain | MIR_motif | 2.64e-04 | 10 | 46 | 2 | IPR016093 | |
| Domain | MS4A | 5.30e-04 | 14 | 46 | 2 | IPR030417 | |
| Domain | CD20-like | 1.33e-03 | 22 | 46 | 2 | IPR007237 | |
| Domain | CD20 | 1.33e-03 | 22 | 46 | 2 | PF04103 | |
| Domain | - | 2.81e-03 | 32 | 46 | 2 | 3.40.1110.10 | |
| Domain | - | 2.81e-03 | 32 | 46 | 2 | 2.70.150.10 | |
| Domain | ATPase_P-typ_cyto_domN | 3.35e-03 | 35 | 46 | 2 | IPR023299 | |
| Domain | P_typ_ATPase | 3.54e-03 | 36 | 46 | 2 | IPR001757 | |
| Domain | ATPase_P-typ_P_site | 3.54e-03 | 36 | 46 | 2 | IPR018303 | |
| Domain | ATPASE_E1_E2 | 3.54e-03 | 36 | 46 | 2 | PS00154 | |
| Domain | ATPase_P-typ_transduc_dom_A | 3.74e-03 | 37 | 46 | 2 | IPR008250 | |
| Domain | E1-E2_ATPase | 3.74e-03 | 37 | 46 | 2 | PF00122 | |
| Domain | LDLRA_1 | 6.23e-03 | 48 | 46 | 2 | PS01209 | |
| Domain | LDLRA_2 | 6.48e-03 | 49 | 46 | 2 | PS50068 | |
| Pathway | REACTOME_TRANSPORT_OF_SMALL_MOLECULES | 2.10e-04 | 681 | 35 | 8 | MM14985 | |
| Pathway | REACTOME_ION_HOMEOSTASIS | 3.19e-04 | 54 | 35 | 3 | M27460 | |
| Pathway | REACTOME_ION_HOMEOSTASIS | 3.19e-04 | 54 | 35 | 3 | MM15202 | |
| Pathway | REACTOME_TRANSPORT_OF_SMALL_MOLECULES | 3.56e-04 | 736 | 35 | 8 | M27287 | |
| Pubmed | TMEM14C is required for erythroid mitochondrial heme metabolism. | 2.47e-09 | 3 | 48 | 3 | 25157825 | |
| Pubmed | Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis. | 8.60e-08 | 7 | 48 | 3 | 19656490 | |
| Pubmed | Identification of the Mitochondrial Heme Metabolism Complex. | 3.22e-06 | 21 | 48 | 3 | 26287972 | |
| Pubmed | 5.59e-06 | 3 | 48 | 2 | 24445321 | ||
| Pubmed | 1.12e-05 | 4 | 48 | 2 | 28800037 | ||
| Pubmed | 1.12e-05 | 4 | 48 | 2 | 9384575 | ||
| Pubmed | 3.90e-05 | 7 | 48 | 2 | 11245982 | ||
| Pubmed | Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. | 5.14e-05 | 292 | 48 | 5 | 12819125 | |
| Pubmed | Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death. | 5.19e-05 | 8 | 48 | 2 | 19033399 | |
| Pubmed | 5.19e-05 | 8 | 48 | 2 | 11784029 | ||
| Pubmed | 6.67e-05 | 9 | 48 | 2 | 11401424 | ||
| Pubmed | Structural organization of the human MS4A gene cluster on Chromosome 11q12. | 8.33e-05 | 10 | 48 | 2 | 11486273 | |
| Pubmed | 8.33e-05 | 10 | 48 | 2 | 18434328 | ||
| Pubmed | 9.81e-05 | 542 | 48 | 6 | 14651853 | ||
| Pubmed | 1.02e-04 | 11 | 48 | 2 | 18285546 | ||
| Pubmed | Mouse model of muscleblind-like 1 overexpression: skeletal muscle effects and therapeutic promise. | 1.02e-04 | 11 | 48 | 2 | 22846424 | |
| Pubmed | Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. | 1.54e-04 | 195 | 48 | 4 | 17110338 | |
| Pubmed | Fat4-Dchs1 signalling controls cell proliferation in developing vertebrae. | 2.21e-04 | 16 | 48 | 2 | 27381226 | |
| Pubmed | Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit. | 3.85e-04 | 21 | 48 | 2 | 28302382 | |
| Pubmed | 5.05e-04 | 24 | 48 | 2 | 27754788 | ||
| Pubmed | 7.39e-04 | 29 | 48 | 2 | 15071553 | ||
| Pubmed | 7.39e-04 | 29 | 48 | 2 | 8617512 | ||
| Pubmed | 1.02e-03 | 34 | 48 | 2 | 26378152 | ||
| Pubmed | 1.08e-03 | 35 | 48 | 2 | 28597972 | ||
| Pubmed | 1.13e-03 | 859 | 48 | 6 | 31536960 | ||
| Pubmed | Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development. | 1.27e-03 | 38 | 48 | 2 | 30786075 | |
| Interaction | TMEM120B interactions | 4.66e-09 | 113 | 44 | 7 | int:TMEM120B | |
| Interaction | AGPAT3 interactions | 1.34e-06 | 88 | 44 | 5 | int:AGPAT3 | |
| Interaction | TLCD1 interactions | 1.45e-05 | 22 | 44 | 3 | int:TLCD1 | |
| Interaction | YIPF4 interactions | 1.45e-05 | 68 | 44 | 4 | int:YIPF4 | |
| Interaction | TMEM11 interactions | 8.05e-05 | 105 | 44 | 4 | int:TMEM11 | |
| Interaction | DGAT1 interactions | 9.77e-05 | 41 | 44 | 3 | int:DGAT1 | |
| Interaction | YIPF6 interactions | 1.22e-04 | 117 | 44 | 4 | int:YIPF6 | |
| Interaction | GPR89A interactions | 1.35e-04 | 120 | 44 | 4 | int:GPR89A | |
| GeneFamily | CD molecules|Membrane spanning 4-domains | 4.01e-04 | 18 | 30 | 2 | 958 | |
| GeneFamily | G protein-coupled receptors, Class A orphans | 7.39e-03 | 78 | 30 | 2 | 262 | |
| GeneFamily | Solute carriers | 2.72e-02 | 395 | 30 | 3 | 752 | |
| Coexpression | MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | 8.33e-08 | 207 | 47 | 7 | MM988 | |
| Coexpression | MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | 3.05e-05 | 202 | 47 | 5 | M12428 | |
| ToppCell | TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-4|TCGA-Brain / Sample_Type by Project: Shred V9 | 1.84e-05 | 149 | 47 | 4 | ff472ad641efd655905e99a9a4cacd5245ab8854 | |
| ToppCell | 343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|343B / Donor, Lineage, Cell class and subclass (all cells) | 3.62e-05 | 177 | 47 | 4 | e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87 | |
| ToppCell | 356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells) | 3.62e-05 | 177 | 47 | 4 | 7617270f49cd6b7ba66db72d20560cee985012b2 | |
| ToppCell | 356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells) | 3.62e-05 | 177 | 47 | 4 | 8220cc2fc0ee8764a67a3be51d75248be2453040 | |
| ToppCell | 343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|343B / Donor, Lineage, Cell class and subclass (all cells) | 3.62e-05 | 177 | 47 | 4 | 43ba6f12c2fb32698a420bf799d46ac1b558f146 | |
| ToppCell | COPD-Multiplet|COPD / Disease state, Lineage and Cell class | 5.38e-05 | 196 | 47 | 4 | 6d02d494196e3f857d53eea46d9419690d43beca | |
| ToppCell | COPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class | 5.38e-05 | 196 | 47 | 4 | af4cdc61830685a888a1209826c23bcf54a43084 | |
| ToppCell | 3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 5.49e-05 | 197 | 47 | 4 | 94a9603cbd3516fbcce871909693b88f20d41713 | |
| ToppCell | Parenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations | 5.49e-05 | 197 | 47 | 4 | 3f078be0b0f5e16edfb6d517beb20ac6178767f0 | |
| ToppCell | Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type | 5.82e-05 | 200 | 47 | 4 | aa1a35dcca3b799241eef4237f6eb94660e019f0 | |
| ToppCell | Brain_organoid-organoid_Tanaka_cellReport-1m-Mesenchymal-BMP_responsible_cell|1m / Sample Type, Dataset, Time_group, and Cell type. | 5.82e-05 | 200 | 47 | 4 | 06d615fe4b7dd5128dbdcd510a5ff3eb480c61b2 | |
| ToppCell | Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09) | 5.82e-05 | 200 | 47 | 4 | a510deaada669e690329183e18df02870bd204b3 | |
| ToppCell | Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 5.82e-05 | 200 | 47 | 4 | dd4228cbed8a4395166a6332e08d44d88bebe3b9 | |
| Disease | heart valve disease (is_marker_for) | 7.13e-06 | 3 | 46 | 2 | DOID:4079 (is_marker_for) | |
| Disease | autosomal dominant polycystic kidney disease (is_implicated_in) | 1.42e-05 | 4 | 46 | 2 | DOID:898 (is_implicated_in) | |
| Disease | polycystic liver disease (implicated_via_orthology) | 4.97e-05 | 7 | 46 | 2 | DOID:0050770 (implicated_via_orthology) | |
| Disease | intracranial aneurysm (is_implicated_in) | 1.55e-04 | 12 | 46 | 2 | DOID:10941 (is_implicated_in) | |
| Disease | autosomal dominant polycystic kidney disease (implicated_via_orthology) | 2.14e-04 | 14 | 46 | 2 | DOID:898 (implicated_via_orthology) | |
| Disease | alcohol use disorder (implicated_via_orthology) | 2.43e-04 | 195 | 46 | 4 | DOID:1574 (implicated_via_orthology) | |
| Disease | renal fibrosis (implicated_via_orthology) | 3.19e-04 | 17 | 46 | 2 | DOID:0050855 (implicated_via_orthology) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| WEAYKAGFGDPHGEF | 241 | Q9BY76 | |
| GVYIGITFGGFWHDY | 206 | Q9H7T0 | |
| GGWDGFCHFFRTPFP | 161 | Q9HD36 | |
| WGPGFGHYVDVFKDL | 4936 | Q6V0I7 | |
| YYHPLGGGREVWFGF | 186 | Q9UL18 | |
| SHGSYRFLAPWIGYG | 116 | Q02928 | |
| WLEKQHGPYGAGAFF | 76 | Q9NW81 | |
| DPVHGGSWFRGAIYY | 281 | O14983 | |
| INFGRWEHGDGYPFD | 171 | P08253 | |
| FGEVHGGRGWFPKSY | 936 | Q9NZM3 | |
| EALPFFLFFHGGYWQ | 86 | Q63HM1 | |
| FHSGWDPDHGGLFYF | 291 | P51606 | |
| PHIFGFTLLGDFIYW | 546 | O75197 | |
| RPFFGYNFGHYLEHW | 501 | Q16822 | |
| VGDTAFWRGPFGDFF | 161 | Q6IPT4 | |
| FIFLSGYPFWGSVLF | 81 | Q9H3V2 | |
| SFFGWGKPGYHGDIF | 176 | Q9Y2T5 | |
| GDFRTHPFFFGLDWD | 331 | Q09013 | |
| DPPHFLYWSGFLGFS | 516 | P15863 | |
| GWPLDRHTYGGSFLY | 296 | Q16134 | |
| YWISGFFFPQGFLTG | 3986 | Q9C0G6 | |
| SCGGPFESWFLFIHF | 386 | Q00597 | |
| GEYLSISFYGGFPFW | 96 | Q9BY19 | |
| FGASTGPGYWDQHYL | 336 | Q8WWB7 | |
| DFFPYADGPHQFWTG | 376 | O00754 | |
| GDPILYQHLFWFFGH | 226 | P00395 | |
| GGFIHWFPLFSGYTL | 391 | P00395 | |
| HGELGHPLYFWFYFV | 176 | Q15125 | |
| FLPSFFHWGKPGYHG | 161 | Q99679 | |
| DLFSYGFDGLHLWSG | 721 | Q92736 | |
| FPGFEAFGLGLSHYW | 56 | Q6W349 | |
| AFGLGLSHYWHLSFP | 61 | Q6W349 | |
| AGFHNVYPYTWGGFS | 331 | Q96PB7 | |
| PAHYLFDWTFGDGSS | 1321 | P98161 | |
| FGYDWSHDYPLFGNL | 36 | Q9P1P4 | |
| GQVLLGWTLHYFPFF | 641 | Q9UKY4 | |
| GLTFLLPFLFFGHFW | 271 | Q9BXJ8 | |
| LFLFYGWPGLFLESA | 226 | Q8WUG5 | |
| IHLYGFWPFGFDPNT | 316 | O43173 | |
| WYHGEVNGIHGFFPT | 171 | Q7Z6J0 | |
| HGYWEVNGFGLFGIY | 956 | Q76KP1 | |
| LGPFLYWTFLAAFEG | 956 | Q8NB49 | |
| SVVPLHWFGFGYAAL | 6 | Q9P0S9 | |
| HWFGFGYAALVASGG | 11 | Q9P0S9 | |
| GFIIYFGYGLWHSEE | 596 | P30825 | |
| FPLVPLHWFGFGYTA | 6 | A8MWL7 | |
| LHWFGFGYTALVVSG | 11 | A8MWL7 | |
| LGPVYGFQWRHFGAE | 131 | P04818 | |
| FPLVPLHWFGFGYTA | 6 | Q9NUH8 | |
| LHWFGFGYTALVVSG | 11 | Q9NUH8 | |
| FYGLSWYQQHDGGAP | 46 | A0A0B4J248 | |
| LYGWSFFLAPAGIFF | 196 | Q6ZP80 | |
| GFNFFPSGIDFSAWG | 121 | Q9Y5A9 | |
| PETVGLIHGSFFWGY | 126 | Q8NDX2 |