Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphatidylinositol-4-phosphate phosphatase activity	SYNJ1 FIG4	3.82e-05	4	51	2	GO:0043812
GeneOntologyMolecularFunction	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	SYNJ1 FIG4	9.53e-05	6	51	2	GO:0043813
GeneOntologyMolecularFunction	protein kinase activity	PHKA2 GUCY2F MAP4K3 RPS6KA1 FGFR3 PRKDC TEX14 FYN	1.29e-04	600	51	8	GO:0004672
GeneOntologyMolecularFunction	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	SYNJ1 FIG4	2.84e-04	10	51	2	GO:0004439
GeneOntologyMolecularFunction	phosphatidylinositol phosphate 4-phosphatase activity	SYNJ1 FIG4	2.84e-04	10	51	2	GO:0034596
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	PHKA2 GUCY2F MAP4K3 RPS6KA1 FGFR3 PRKDC TEX14 FYN	4.00e-04	709	51	8	GO:0016773
GeneOntologyMolecularFunction	phosphatidylinositol-4,5-bisphosphate phosphatase activity	SYNJ1 FIG4	4.15e-04	12	51	2	GO:0106019
GeneOntologyMolecularFunction	phosphatidylinositol phosphate 5-phosphatase activity	SYNJ1 FIG4	4.90e-04	13	51	2	GO:0034595
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	PHKA2 GUCY2F MAP4K3 RPS6KA1 FGFR3 PRKDC PIGG TEX14 FYN	5.50e-04	938	51	9	GO:0016772
GeneOntologyMolecularFunction	phosphatidylinositol-3-phosphate phosphatase activity	SYNJ1 FIG4	5.71e-04	14	51	2	GO:0004438
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	DCAF6 DET1 MTA3 ANK3 SORBS1 SUV39H2 BANK1 CUX1 WWC1 STRIP1	6.07e-04	1160	51	10	GO:0030674
GeneOntologyMolecularFunction	kinase activity	PHKA2 GUCY2F MAP4K3 RPS6KA1 FGFR3 PRKDC TEX14 FYN	6.56e-04	764	51	8	GO:0016301
GeneOntologyMolecularFunction	phosphatidylinositol monophosphate phosphatase activity	SYNJ1 FIG4	6.57e-04	15	51	2	GO:0052744
GeneOntologyMolecularFunction	phosphatidylinositol-3,5-bisphosphate phosphatase activity	SYNJ1 FIG4	7.50e-04	16	51	2	GO:0106018
GeneOntologyMolecularFunction	adenylate cyclase activity	ADCY4 GUCY2F	9.53e-04	18	51	2	GO:0004016
GeneOntologyMolecularFunction	transmembrane transporter binding	PDE4D ANK3 FGF13 FYN	9.69e-04	172	51	4	GO:0044325
GeneOntologyMolecularFunction	cyclase activity	ADCY4 GUCY2F	1.70e-03	24	51	2	GO:0009975
GeneOntologyMolecularFunction	phosphorus-oxygen lyase activity	ADCY4 GUCY2F	1.85e-03	25	51	2	GO:0016849
GeneOntologyMolecularFunction	molecular adaptor activity	DCAF6 DET1 MTA3 ANK3 SORBS1 SUV39H2 BANK1 CUX1 WWC1 STRIP1	1.99e-03	1356	51	10	GO:0060090
GeneOntologyMolecularFunction	phosphatidylinositol bisphosphate phosphatase activity	SYNJ1 FIG4	2.16e-03	27	51	2	GO:0034593
GeneOntologyMolecularFunction	phosphatidylinositol phosphate phosphatase activity	SYNJ1 FIG4	2.66e-03	30	51	2	GO:0052866
GeneOntologyMolecularFunction	phospholipase binding	FYN BANK1	3.02e-03	32	51	2	GO:0043274
GeneOntologyMolecularFunction	signaling adaptor activity	SORBS1 BANK1 WWC1	4.38e-03	129	51	3	GO:0035591
GeneOntologyCellularComponent	anchoring junction	DPP4 RRAS2 DCAF6 ANK3 AMOTL1 MTSS1 FGF13 SORBS1 FGFR3 RRAS	1.05e-04	976	51	10	GO:0070161
Domain	Syja_N	SYNJ1 FIG4	7.27e-05	5	51	2	PF02383
Domain	SAC	SYNJ1 FIG4	7.27e-05	5	51	2	PS50275
Domain	SAC_dom	SYNJ1 FIG4	7.27e-05	5	51	2	IPR002013
Domain	RAS	RRAS2 RASL11A RRAS	1.18e-04	35	51	3	PS51421
Domain	Small_GTPase_Ras	RRAS2 RASL11A RRAS	1.40e-04	37	51	3	IPR020849
Domain	Pkinase_Tyr	GUCY2F FGFR3 TEX14 FYN	4.22e-04	129	51	4	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	GUCY2F FGFR3 TEX14 FYN	5.45e-04	138	51	4	IPR001245
Domain	Kinase-like_dom	GUCY2F MAP4K3 RPS6KA1 FGFR3 PRKDC TEX14 FYN	6.38e-04	542	51	7	IPR011009
Domain	A/G_cyclase_CS	ADCY4 GUCY2F	9.68e-04	17	51	2	IPR018297
Domain	Nucleotide_cyclase	ADCY4 GUCY2F	1.09e-03	18	51	2	IPR029787
Domain	-	ADCY4 GUCY2F	1.09e-03	18	51	2	3.30.70.1230
Domain	GUANYLATE_CYCLASE_1	ADCY4 GUCY2F	1.21e-03	19	51	2	PS00452
Domain	Guanylate_cyc	ADCY4 GUCY2F	1.21e-03	19	51	2	PF00211
Domain	GUANYLATE_CYCLASE_2	ADCY4 GUCY2F	1.21e-03	19	51	2	PS50125
Domain	A/G_cyclase	ADCY4 GUCY2F	1.21e-03	19	51	2	IPR001054
Domain	CYCc	ADCY4 GUCY2F	1.21e-03	19	51	2	SM00044
Domain	Prot_kinase_dom	GUCY2F MAP4K3 RPS6KA1 FGFR3 TEX14 FYN	2.07e-03	489	51	6	IPR000719
Domain	PROTEIN_KINASE_DOM	GUCY2F MAP4K3 RPS6KA1 FGFR3 TEX14 FYN	2.16e-03	493	51	6	PS50011
Domain	Ras	RRAS2 RASL11A RRAS	6.09e-03	136	51	3	PF00071
Domain	WW	ARHGAP27 WWC1	7.31e-03	47	51	2	PF00397
Domain	WW	ARHGAP27 WWC1	7.61e-03	48	51	2	SM00456
Domain	WW_DOMAIN_2	ARHGAP27 WWC1	8.56e-03	51	51	2	PS50020
Domain	WW_DOMAIN_1	ARHGAP27 WWC1	8.56e-03	51	51	2	PS01159
Domain	WW_dom	ARHGAP27 WWC1	8.88e-03	52	51	2	IPR001202
Domain	Small_GTPase	RRAS2 RASL11A RRAS	9.51e-03	160	51	3	IPR001806
Domain	Small_GTP-bd_dom	RRAS2 RASL11A RRAS	1.07e-02	167	51	3	IPR005225
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA4 RRAS FYN	6.98e-06	14	39	3	M7578
Pathway	KEGG_MAPK_SIGNALING_PATHWAY	RRAS2 MAP4K3 FOS RPS6KA1 FGF13 FGFR3 RRAS	7.40e-06	267	39	7	M10792
Pathway	WP_MAPK_SIGNALING	RRAS2 MAP4K3 FOS FGF13 FGFR3 RRAS	5.35e-05	246	39	6	M39597
Pathway	BIOCARTA_TSP1_PATHWAY	FOS FYN	1.55e-04	7	39	2	M22039
Pathway	BIOCARTA_TSP1_PATHWAY	FOS FYN	1.55e-04	7	39	2	MM1559
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA4 FYN	2.65e-04	9	39	2	MM15030
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	PLXNA4 RRAS FYN	3.72e-04	51	39	3	MM14967
Pathway	PID_FGF_PATHWAY	FOS RPS6KA1 FGFR3	4.65e-04	55	39	3	M276
Pathway	WP_KIT_RECEPTOR_SIGNALING	FOS RPS6KA1 FYN	5.72e-04	59	39	3	M39350
Pathway	WP_TCELL_ANTIGEN_RECEPTOR_TCR_PATHWAY_DURING_STAPHYLOCOCCUS_AUREUS_INFECTION	FOS RRAS FYN	6.61e-04	62	39	3	M39429
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA4 FYN	6.65e-04	14	39	2	MM15029
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	PLXNA4 RRAS FYN	7.26e-04	64	39	3	M7923
Pathway	WP_REGULATION_OF_ACTIN_CYTOSKELETON	RRAS2 FGF13 FGFR3 RRAS	7.58e-04	150	39	4	M39520
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA4 FYN	7.65e-04	15	39	2	MM15031
Pathway	WP_THYROID_STIMULATING_HORMONE_TSH_SIGNALING	PDE4D FOS RPS6KA1	7.94e-04	66	39	3	M39684
Pathway	WP_REGULATION_OF_ACTIN_CYTOSKELETON	RRAS2 FGF13 FGFR3 RRAS	7.97e-04	152	39	4	MM15834
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA4 FYN	8.73e-04	16	39	2	M16498
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA4 FYN	8.73e-04	16	39	2	M8245
Pathway	WP_INSULIN_SIGNALING	MAP4K3 FOS RPS6KA1 SORBS1	9.65e-04	160	39	4	MM15956
Pathway	WP_INSULIN_SIGNALING	MAP4K3 FOS RPS6KA1 SORBS1	9.65e-04	160	39	4	M39482
Pathway	WP_INHIBITION_OF_EXOSOME_BIOGENESIS_AND_SECRETION_BY_MANUMYCIN_A_IN_CRPC_CELLS	RRAS2 RRAS	1.11e-03	18	39	2	M39737
Pubmed	R-Ras1 and R-Ras2 Expression in Anatomical Regions and Cell Types of the Central Nervous System.	RRAS2 RRAS	2.11e-06	2	51	2	35055164
Pubmed	Absence of R-Ras1 and R-Ras2 causes mitochondrial alterations that trigger axonal degeneration in a hypomyelinating disease model.	RRAS2 RRAS	2.11e-06	2	51	2	33010069
Pubmed	R-Ras is required for murine dendritic cell maturation and CD4+ T-cell priming.	RRAS2 RRAS	2.11e-06	2	51	2	22174156
Pubmed	Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis.	PHKA2 RRAS2 RRAS	5.15e-06	23	51	3	12620389
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ADCY4 PDE4D ANK3 SYNJ1 MAP4K3 PLXNA4 PSD3 FGF13 SORBS1 DNAH6 STRIP1	5.75e-06	1431	51	11	37142655
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	PHKA2 RRAS2 DCAF6 PDE4D BCAS2 PRKDC SGF29 FYN PLOD1 STRIP1	5.81e-06	1155	51	10	20360068
Pubmed	R-Ras controls axon branching through afadin in cortical neurons.	RRAS2 RRAS	6.32e-06	3	51	2	22593211
Pubmed	Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3.	RRAS2 RRAS	6.32e-06	3	51	2	10777492
Pubmed	H-Ras, R-Ras, and TC21 differentially regulate ureteric bud cell branching morphogenesis.	RRAS2 RRAS	6.32e-06	3	51	2	16467383
Pubmed	Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells.	RRAS2 RRAS	6.32e-06	3	51	2	14724565
Pubmed	L1 coupling to ankyrin and the spectrin-actin cytoskeleton modulates ethanol inhibition of L1 adhesion and ethanol teratogenesis.	ANK3 RPS6KA1	6.32e-06	3	51	2	29109170
Pubmed	Alteration of a cyclic AMP-dependent protein kinase phosphorylation site in the c-Fos protein augments its transforming potential.	FOS RPS6KA1	6.32e-06	3	51	2	1545828
Pubmed	Quetiapine and aripiprazole signal differently to ERK, p90RSK and c-Fos in mouse frontal cortex and striatum: role of the EGF receptor.	FOS RPS6KA1	1.26e-05	4	51	2	24552586
Pubmed	R-Ras subfamily proteins elicit distinct physiologic effects and phosphoproteome alterations in neurofibromin-null MPNST cells.	RRAS2 RRAS	1.26e-05	4	51	2	34530870
Pubmed	Phosphorylation of KIBRA by the extracellular signal-regulated kinase (ERK)-ribosomal S6 kinase (RSK) cascade modulates cell proliferation and migration.	RPS6KA1 WWC1	1.26e-05	4	51	2	24269383
Pubmed	R-Ras2 is required for germinal center formation to aid B cells during energetically demanding processes.	RRAS2 RRAS	1.26e-05	4	51	2	29844052
Pubmed	R-Ras1 and R-Ras2 Are Essential for Oligodendrocyte Differentiation and Survival for Correct Myelination in the Central Nervous System.	RRAS2 RRAS	1.26e-05	4	51	2	29720552
Pubmed	Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase.	FOS RPS6KA1	1.26e-05	4	51	2	8248197
Pubmed	Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays.	PHKA2 DPP4 FYN	1.30e-05	31	51	3	14684825
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DCAF6 CFAP91 MTA3 ANK3 SYNJ1 HLCS ASTN2 SORBS1 PRKDC CUX1	1.47e-05	1285	51	10	35914814
Pubmed	Common variants at 12q14 and 12q24 are associated with hippocampal volume.	DPP4 ASTN2	2.10e-05	5	51	2	22504421
Pubmed	Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily.	RRAS2 RRAS	2.10e-05	5	51	2	10224125
Pubmed	Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3.	MTA3 FYN	2.10e-05	5	51	2	11483358
Pubmed	Epidermal growth factor stimulates RSK2 activation through activation of the MEK/ERK pathway and src-dependent tyrosine phosphorylation of RSK2 at Tyr-529.	FGFR3 FYN	3.15e-05	6	51	2	18156174
Pubmed	The adaptor molecule SAP plays essential roles during invariant NKT cell cytotoxicity and lytic synapse formation.	PRKDC FYN	3.15e-05	6	51	2	23430111
Pubmed	Characterization of R-ras3/m-ras null mice reveals a potential role in trophic factor signaling.	RRAS2 RRAS	3.15e-05	6	51	2	16980617
Pubmed	Deficient tyrosine phosphorylation of c-Cbl and associated proteins in phorbol ester-resistant EL4 mouse thymoma cells.	FOS FYN	3.15e-05	6	51	2	9115297
Pubmed	FoxO6 affects Plxna4-mediated neuronal migration during mouse cortical development.	PLXNA4 CUX1	4.41e-05	7	51	2	27791111
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	AMOTL1 SORBS1 PRKDC PLOD1 WWC1 STRIP1	4.75e-05	446	51	6	24255178
Pubmed	Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.	PLXNA4 FYN	5.87e-05	8	51	2	28637841
Pubmed	GABAergic neuronal IL-4R mediates T cell effect on memory.	FOS PRKDC	5.87e-05	8	51	2	34793707
Pubmed	PlexinA4-Semaphorin3A-mediated crosstalk between main cortical interneuron classes is required for superficial interneuron lamination.	PLXNA4 CUX1	7.54e-05	9	51	2	33503438
Pubmed	The unique N-terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains.	PDE4D FYN	7.54e-05	9	51	2	10571082
Pubmed	The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1.	RRAS2 RRAS	7.54e-05	9	51	2	11857081
Pubmed	BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling.	FYN BANK1	7.54e-05	9	51	2	23555801
Pubmed	A human MAP kinase interactome.	ANK3 MAP4K3 FOS SORBS1 PRKDC CUX1	7.63e-05	486	51	6	20936779
Pubmed	Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain.	FGFR3 FYN	9.42e-05	10	51	2	12244095
Pubmed	Fibroblast growth factor 13 is a microtubule-stabilizing protein regulating neuronal polarization and migration.	FGF13 CUX1	1.15e-04	11	51	2	22726441
Pubmed	Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.	AMOTL1 USH2A	1.15e-04	11	51	2	24349473
Pubmed	Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localization.	RRAS2 RRAS	1.15e-04	11	51	2	15031288
Pubmed	CRL5-dependent regulation of the small GTPases ARL4C and ARF6 controls hippocampal morphogenesis.	FYN CUX1	1.38e-04	12	51	2	32873638
Pubmed	Conservation and reorganization of loci on the mammalian X chromosome: a molecular framework for the identification of homologous subchromosomal regions in man and mouse.	PHKA2 F8	1.38e-04	12	51	2	2899541
Pubmed	Absence of Fyn and Src causes a reeler-like phenotype.	FYN CUX1	1.63e-04	13	51	2	16162939
Pubmed	Plexin signaling via off-track and rho family GTPases.	PLXNA4 FYN	1.63e-04	13	51	2	11604131
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	PDE4D SYNJ1 BCAS2 FGFR3 FYN	1.79e-04	358	51	5	32460013
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	ANK3 FGFR3 PRKDC DNAH6 FHIP2B	1.86e-04	361	51	5	26167880
Pubmed	Mapping of a liver phosphorylase kinase alpha-subunit gene on the mouse X chromosome.	PHKA2 F8	1.90e-04	14	51	2	8432533
Pubmed	Genome-wide meta-analysis identifies new susceptibility loci for migraine.	ASTN2 SORBS1 SUV39H2	2.09e-04	78	51	3	23793025
Pubmed	Noonan Syndrome	RRAS2 RRAS	2.19e-04	15	51	2	20301303
Pubmed	Enhanced FGFR3 activity in postmitotic principal neurons during brain development results in cortical dysplasia and axonal tract abnormality.	FGFR3 CUX1	2.19e-04	15	51	2	33116259
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	SYNJ1 MAP4K3 ARFGAP3 HLCS SORBS1 PLOD1 FHIP2B	2.36e-04	853	51	7	28718761
Pubmed	Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.	ANK3 FGFR3 CUX1	2.42e-04	82	51	3	31073041
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADCY4 USH2A	2.50e-04	16	51	2	17567809
Pubmed	Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex.	FYN CUX1	2.50e-04	16	51	2	26235615
Pubmed	DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.	PRKDC CUX1	2.50e-04	16	51	2	28123024
Pubmed	Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness.	PDE4D CUX1	2.50e-04	16	51	2	28283561
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	ARFGAP3 CSPG5 PSD3 ASTN2 FYN	3.16e-04	405	51	5	38187761
Pubmed	Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis.	ANK3 SYNJ1	3.18e-04	18	51	2	33323119
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	PHKA2 MTA3 MAP4K3 RPS6KA1 FGFR3 FYN PLOD1	3.48e-04	910	51	7	36736316
Pubmed	Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex.	RPS6KA1 CUX1	3.94e-04	20	51	2	26848828
Pubmed	Heritability and genetic association analysis of cognition in the Diabetes Heart Study.	MTSS1 PLXNA4	4.35e-04	21	51	2	24684796
Pubmed	Expression of members of the Fgf family and their receptors during midfacial development.	FGF13 FGFR3	4.78e-04	22	51	2	11165488
Pubmed	FGF signaling expands embryonic cortical surface area by regulating Notch-dependent neurogenesis.	FGFR3 CUX1	4.78e-04	22	51	2	22031906
Pubmed	Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease.	RRAS2 FYN	4.78e-04	22	51	2	18628988
Pubmed	Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunction.	DPP4 SORBS1 ANGPTL1	5.01e-04	105	51	3	24667918
Pubmed	Expression of mouse fibroblast growth factor and fibroblast growth factor receptor genes during early inner ear development.	FGF13 FGFR3	5.23e-04	23	51	2	14517998
Pubmed	Gene expression profiles of mouse submandibular gland development: FGFR1 regulates branching morphogenesis in vitro through BMP- and FGF-dependent mechanisms.	FGF13 FGFR3	5.70e-04	24	51	2	12421715
Pubmed	Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome.	SORBS1 FYN	6.19e-04	25	51	2	16374509
Pubmed	Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.	AMOTL1 WWC1	6.70e-04	26	51	2	28720576
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	C1orf54 BCAS2 RPS6KA1 PLOD1 USH2A ANGPTL1 STRIP1	7.32e-04	1031	51	7	16710414
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	PDE4D ANK3 SYNJ1 SORBS1	7.73e-04	281	51	4	28706196
Pubmed	FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system.	FGF13 FGFR3	8.35e-04	29	51	2	21876757
Pubmed	NPAS1 represses the generation of specific subtypes of cortical interneurons.	FGFR3 CUX1	8.35e-04	29	51	2	25467980
Pubmed	Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells.	DPP4 PLXNA4	8.35e-04	29	51	2	22424930
Pubmed	Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.	PLXNA4 FGFR3 CUX1	8.52e-04	126	51	3	16284245
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	ANK3 SYNJ1 SORBS1	8.91e-04	128	51	3	30995482
Pubmed	Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.	MTSS1 PSD3	8.93e-04	30	51	2	20080650
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ANK3 ARFGAP3 AMOTL1 PRKDC CUX1 STRIP1	9.34e-04	777	51	6	35844135
Pubmed	Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform.	FGF13 FGFR3	9.54e-04	31	51	2	16123981
Pubmed	Genome-wide association study of periodontal pathogen colonization.	FOS WWC1	9.54e-04	31	51	2	22699663
Pubmed	RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors.	DNAJB7 FGFR3	1.02e-03	32	51	2	20111592
Pubmed	Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.	TEX14 FYN	1.02e-03	32	51	2	20056645
Pubmed	Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.	DCAF6 DET1	1.02e-03	32	51	2	16964240
Pubmed	Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry.	BCAS2 PRKDC	1.15e-03	34	51	2	11101529
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ANK3 SYNJ1 AMOTL1 PRKDC CUX1	1.24e-03	549	51	5	38280479
Pubmed	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.	DCAF6 DET1	1.36e-03	37	51	2	16949367
Pubmed	The genetic architecture of economic and political preferences.	PLXNA4 ASTN2	1.36e-03	37	51	2	22566634
Pubmed	Sequence-ready physical map of the mouse chromosome 16 region with conserved synteny to the human velocardiofacial syndrome region on 22q11.2.	HLCS PRKDC	1.36e-03	37	51	2	10337614
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DCAF6 PDE4D MTA3 ANK3 ASTN2 FGF13 PLOD1 CUX1	1.37e-03	1489	51	8	28611215
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	MAP4K3 RRAS FYN SUV39H2	1.38e-03	329	51	4	17474147
GeneFamily	RAS type GTPase family	RRAS2 RASL11A RRAS	2.88e-05	31	35	3	389
GeneFamily	Phosphoinositide phosphatases	SYNJ1 FIG4	1.74e-03	32	35	2	1079
Coexpression	CHANDRAN_METASTASIS_DN	DPP4 FOS PSD3 FGF13 SORBS1 ARHGAP27 RRAS	2.55e-06	316	51	7	M11615
Coexpression	GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP	DPP4 DCAF6 MTSS1 ANGPTL1 CUX1	1.78e-05	166	51	5	M7009
Coexpression	GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN	DPP4 RRAS2 DCAF6 MTSS1 ANGPTL1	1.89e-05	168	51	5	M7007
Coexpression	BLALOCK_ALZHEIMERS_DISEASE_DN	DCAF6 PDE4D ANK3 SYNJ1 MAP4K3 BCAS2 CSPG5 PSD3 FGF13 FGFR3 F8	2.24e-05	1248	51	11	M17728
Coexpression	CUI_TCF21_TARGETS_2_DN	DPP4 RRAS2 PDE4D RASL11A AMOTL1 MTSS1 PSD3 SORBS1 FYN	3.53e-05	854	51	9	M1533
Coexpression	GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN	MAP4K3 MTSS1 PSD3 HLCS CUX1	4.24e-05	199	51	5	M312
Coexpression	GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_UP	MTA3 MAP4K3 FYN BANK1 CUX1	4.35e-05	200	51	5	M9447
Coexpression	GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_DN	C1orf54 RRAS2 MAP4K3 FOS F8	4.35e-05	200	51	5	M8027
Coexpression	CUI_TCF21_TARGETS_2_DN	DPP4 RRAS2 PDE4D RASL11A AMOTL1 MTSS1 PSD3 SORBS1 FYN	4.78e-05	888	51	9	MM1018
Coexpression	LAKE_ADULT_KIDNEY_C17_COLLECTING_SYSTEM_PCS_STRESSED_DISSOC_SUBSET	PDE4D ANK3 MAP4K3 FOS WWC1	1.03e-04	240	51	5	M39236
Coexpression	FOURATI_BLOOD_TWINRIX_AGE_25_83YO_RESPONDERS_VS_POOR_RESPONDERS_0DY_UP	DPP4 RRAS2 ANK3 BCAS2 AMOTL1 ANGPTL1 BANK1	1.34e-04	587	51	7	M40869
Coexpression	BOYAULT_LIVER_CANCER_SUBCLASS_G123_DN	PSD3 FYN F8	1.35e-04	51	51	3	M2218
Coexpression	HUTTMANN_B_CLL_POOR_SURVIVAL_DN	RRAS2 MTSS1 BANK1	2.09e-04	59	51	3	M12653
Coexpression	STK33_NOMO_UP	SYNJ1 MAP4K3 FOS MTSS1 PSD3	2.48e-04	290	51	5	M2855
Coexpression	GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN	SYNJ1 PRKDC ANGPTL1 STRIP1	2.49e-04	157	51	4	M7733
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	PDE4D ANK3 SYNJ1 CSPG5 MTSS1 RASGEF1B PLXNA4 SORBS1 STRIP1	2.52e-04	1106	51	9	M39071
Coexpression	GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP	DCAF6 MTSS1 ANGPTL1 CUX1	2.80e-04	162	51	4	M7005
Coexpression	ONDER_CDH1_TARGETS_2_DN	ANK3 FOS RPS6KA1 MTSS1 FGFR3 WWC1	3.03e-04	473	51	6	M4306
Coexpression	HOEGERKORP_CD44_TARGETS_DIRECT_DN	GUCY2F HLCS	3.33e-04	14	51	2	M1823
Coexpression	LAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE	PDE4D ANK3 MAP4K3 FGF13	3.44e-04	171	51	4	M39234
Coexpression	GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_UP	PLXNA4 PSD3 PLOD1 BANK1	3.44e-04	171	51	4	M6746
Coexpression	ZHONG_PFC_C3_MICROGLIA	RRAS2 ANK3 PLXNA4 FGF13 FYN WWC1	3.58e-04	488	51	6	M39104
Coexpression	GSE14699_NAIVE_VS_ACT_CD8_TCELL_DN	RRAS2 DCAF6 ANGPTL1 CUX1	3.76e-04	175	51	4	M2940
Coexpression	LAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2	PDE4D ANK3 CUX1 WWC1	3.84e-04	176	51	4	M39223
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBGABA	PDE4D ANK3 MTSS1 RASGEF1B PLXNA4 FGF13 STRIP1	4.02e-04	703	51	7	M39070
Coexpression	GSE3565_DUSP1_VS_WT_SPLENOCYTES_DN	DPP4 RRAS2 RPS6KA1 MTSS1	4.09e-04	179	51	4	M6324
Coexpression	GSE10422_WT_VS_BAFF_TRANSGENIC_LN_BCELL_UP	PDE4D SYNJ1 MTSS1 STRIP1	4.18e-04	180	51	4	M357
Coexpression	GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP	PHKA2 PDE4D FOS RASGEF1B	4.63e-04	185	51	4	M8792
Coexpression	GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_DN	PHKA2 C1orf54 MAP4K3 FOS	5.76e-04	196	51	4	M8717
Coexpression	GSE27786_BCELL_VS_CD8_TCELL_DN	DPP4 SYNJ1 FGF13 PRKDC	6.09e-04	199	51	4	M4802
Coexpression	GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_UP	RRAS2 MTSS1 PSD3 FYN	6.09e-04	199	51	4	M5213
Coexpression	GSE14350_TREG_VS_TEFF_UP	MAP4K3 MTSS1 PRKDC FYN	6.09e-04	199	51	4	M3417
Coexpression	GSE32986_CURDLAN_HIGHDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP	PHKA2 C1orf54 DCAF6 SYNJ1	6.09e-04	199	51	4	M8636
Coexpression	GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP	DPP4 C1orf54 RPS6KA1 MTSS1	6.09e-04	199	51	4	M8639
Coexpression	GSE3982_MAST_CELL_VS_NEUTROPHIL_UP	DCAF6 DET1 MTSS1 PIGG	6.09e-04	199	51	4	M5432
Coexpression	GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN	RRAS2 RPS6KA1 PRKDC CDCA4	6.09e-04	199	51	4	M3197
Coexpression	GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN	C1orf54 MTSS1 ANGPTL1 BANK1	6.21e-04	200	51	4	M9463
Coexpression	GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN	C1orf54 MTA3 MAP4K3 ANGPTL1	6.21e-04	200	51	4	M9459
Coexpression	GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_DN	RRAS2 PRKDC RRAS F8	6.21e-04	200	51	4	M5975
Coexpression	GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_DN	PHKA2 MTA3 MAP4K3 RASGEF1B	6.21e-04	200	51	4	M8052
Coexpression	GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_UP	C1orf54 ANK3 FOS SGF29	6.21e-04	200	51	4	M4590
Coexpression	GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN	MTA3 SORBS1 FYN BANK1	6.21e-04	200	51	4	M309
Coexpression	GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_UP	FGF13 SGF29 SUV39H2 BANK1	6.21e-04	200	51	4	M7991
Coexpression	GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_UP	ARHGAP27 SGF29 FYN PLOD1	6.21e-04	200	51	4	M7922
Coexpression	GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_UP	MAP4K3 PSD3 FYN BANK1	6.21e-04	200	51	4	M7856
Coexpression	GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_UP	DPP4 RASL11A ARFGAP3 FYN	6.21e-04	200	51	4	M6573
Coexpression	GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_UP	DPP4 DET1 HLCS FYN	6.21e-04	200	51	4	M3419
Coexpression	GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_UP	PHKA2 DPP4 DET1 ANK3	6.21e-04	200	51	4	M9886
Coexpression	GSE42724_MEMORY_BCELL_VS_PLASMABLAST_DN	PHKA2 MTA3 PSD3 FYN	6.21e-04	200	51	4	M9791
Coexpression	GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_DN	PHKA2 MTA3 MTSS1 PRKDC	6.21e-04	200	51	4	M6745
Coexpression	GSE36078_WT_VS_IL1R_KO_LUNG_DC_DN	CFAP91 DET1 FGF13 CUX1	6.21e-04	200	51	4	M9290
Coexpression	GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_UP	SYNJ1 FIG4 PRKDC PLOD1	6.21e-04	200	51	4	M6158
Coexpression	GSE17721_PAM3CSK4_VS_CPG_8H_BMDC_DN	FOS MTSS1 FGF13 F8	6.21e-04	200	51	4	M3866
Coexpression	GSE6674_ANTI_IGM_VS_PL2_3_STIM_BCELL_UP	DPP4 DCAF6 BCAS2 RRAS	6.21e-04	200	51	4	M6930
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_top-relative-expression-ranked_1000	MTA3 ANK3 FIG4 BCAS2 FOS MTSS1 HLCS FGF13 FGFR3 CUX1 WWC1	1.54e-06	780	50	11	gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_1000
CoexpressionAtlas	dev gonad_e13.5_F_DevVascOvary_Flk_top-relative-expression-ranked_1000	C1orf54 ADCY4 PDE4D MAP4K3 AMOTL1 MTSS1 ARHGAP27 RRAS FYN PLOD1	1.98e-05	831	50	10	gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_1000
CoexpressionAtlas	dev gonad_e12.5_M_DevVasTestis_Flk_top-relative-expression-ranked_1000	C1orf54 ADCY4 PDE4D MAP4K3 AMOTL1 MTSS1 RASGEF1B ARHGAP27 RRAS FYN	2.33e-05	847	50	10	gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Endothelial cells_emap-29977_top-relative-expression-ranked_500	ADCY4 FOS RPS6KA1 MTSS1 F8 BANK1 CUX1	3.06e-05	384	50	7	DevelopingKidney_e15.5_Endothelial cells_emap-29977_500
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	C1orf54 RRAS2 DCAF6 MTA3 FIG4 MAP4K3 FOS RASGEF1B PLXNA4	9.50e-05	804	50	9	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_1000
CoexpressionAtlas	dev gonad_e12.5_F_DevVasOvary_Flk_top-relative-expression-ranked_1000	C1orf54 ADCY4 PDE4D MAP4K3 FOS RPS6KA1 MTSS1 ARHGAP27 FYN	1.07e-04	817	50	9	gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_1000
CoexpressionAtlas	dev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_1000	C1orf54 ADCY4 PDE4D FOS AMOTL1 MTSS1 RASGEF1B ARHGAP27 FYN	1.07e-04	817	50	9	gudmap_dev gonad_e11.5_F_ReproVasc_Flk_1000
CoexpressionAtlas	dev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_1000	C1orf54 ADCY4 PDE4D MAP4K3 MTSS1 ARHGAP27 RRAS	2.11e-04	523	50	7	gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k4_1000
CoexpressionAtlas	kidney_e13.5_Podocyte_MafB_k-means-cluster#2_top-relative-expression-ranked_500	DPP4 PSD3 ANGPTL1	2.23e-04	50	50	3	gudmap_kidney_e13.5_Podocyte_MafB_k2_500
CoexpressionAtlas	DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#5_top-relative-expression-ranked_200	FOS F8 BANK1	2.80e-04	54	50	3	gudmap_developingKidney_e15.5_Podocyte cells_200_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#4_top-relative-expression-ranked_500	FOS FGF13 CUX1	2.80e-04	54	50	3	gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_500_k4
CoexpressionAtlas	B cells, B.Fo.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1- CD23+, Spleen, avg-3	RASGEF1B ANGPTL1 BANK1	2.96e-04	55	50	3	GSM538201_100
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 RASL11A AMOTL1 ARHGAP27 F8	2.02e-06	181	51	5	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDE4D ANK3 ASTN2 FGF13 WWC1	2.36e-06	187	51	5	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	RRAS2 PDE4D ANK3 FYN WWC1	2.43e-06	188	51	5	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	RRAS2 PDE4D ANK3 PSD3 SORBS1	2.56e-06	190	51	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADCY4 BCAS2 FOS FYN F8	2.56e-06	190	51	5	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPP4 PDE4D ANK3 BCAS2 FOS	2.62e-06	191	51	5	142f98cabf8737b28369315b3d7a0797ded88e03
ToppCell	Control-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	RRAS2 PDE4D ANK3 SORBS1 WWC1	2.69e-06	192	51	5	1bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D ANK3 ASTN2 CUX1 WWC1	2.76e-06	193	51	5	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D ANK3 ASTN2 CUX1 WWC1	2.76e-06	193	51	5	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	CFAP91 PDE4D ANK3 DNAH6 WWC1	2.98e-06	196	51	5	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	CFAP91 PDE4D ANK3 DNAH6 WWC1	2.98e-06	196	51	5	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	FOS CSPG5 PLXNA4 FGFR3 WWC1	3.05e-06	197	51	5	965d5a3f8c9b12cb8a8d3429702ae29ebd8c6122
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial-Astroglia\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	FOS CSPG5 PLXNA4 FGFR3 WWC1	3.05e-06	197	51	5	3f088eb29197bc575400d6dafd8083e69e4a149f
ToppCell	mLN-T_cell-Th1\|mLN / Region, Cell class and subclass	PDE4D BCAS2 FOS CSPG5 FYN	3.13e-06	198	51	5	7627b7c3a248da2bd5e1e6f7c226e5fd0bc92113
ToppCell	mLN-(1)_T_cell-(12)_Th1\|mLN / shred on region, Cell_type, and subtype	PDE4D BCAS2 FOS CSPG5 FYN	3.13e-06	198	51	5	1fe8257233232b264b9ca630c2d92c509a195353
ToppCell	Severe-B_intermediate-10\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK3 MAP4K3 FOS MTSS1 BANK1	3.13e-06	198	51	5	dfae26c3513a82bb7cb8dadbfcea2a1f420b1bab
ToppCell	COVID-19-lung-Capillary_2\|lung / Disease (COVID-19 only), tissue and cell type	ADCY4 RASGEF1B SORBS1 FYN F8	3.21e-06	199	51	5	793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	PDE4D ANK3 MAP4K3 RASGEF1B HLCS	3.21e-06	199	51	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MTA3 MTSS1 ANGPTL1 BANK1	2.63e-05	150	51	4	4bdcdce40f54580c7a4e1416b468e657ba8874fc
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122\|Adult / Lineage, Cell type, age group and donor	PDE4D ANK3 FGFR3 WWC1	3.14e-05	157	51	4	31d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D ANK3 MAP4K3 FGF13	3.14e-05	157	51	4	2c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDE4D MTA3 ANK3 WWC1	3.90e-05	166	51	4	c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	MTSS1 RASGEF1B ANGPTL1 BANK1	4.58e-05	173	51	4	d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASL11A FGF13 DNAJB7 SUV39H2	4.69e-05	174	51	4	41eb0a214a8b4015a26311f77061c8147144f0e7
ToppCell	LPS_only-Lymphocytic_B-B_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MTSS1 RASGEF1B ANGPTL1 BANK1	5.01e-05	177	51	4	c82332c5f656aa26513e4f7525d5d4d733019725
ToppCell	Endothelial-Endothelial-C\|Endothelial / shred on cell class and cell subclass (v4)	C1orf54 ADCY4 MAP4K3 RASGEF1B	5.01e-05	177	51	4	b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCell	LPS_only-Lymphocytic_B\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MTSS1 RASGEF1B ANGPTL1 BANK1	5.01e-05	177	51	4	5ed65e08d773d157840317c72e0d43c261d438d4
ToppCell	LPS_only-Lymphocytic_B-B_cells-B-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MTSS1 RASGEF1B ANGPTL1 BANK1	5.01e-05	177	51	4	8a955a7ab84c434f9ad4b467246b8be3cb479406
ToppCell	Severe-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK3 MAP4K3 MTSS1 BANK1	5.12e-05	178	51	4	b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCell	IIF-Lymphocyte-T_NK-MAIT\|IIF / Disease, Lineage and Cell Type	DPP4 PDE4D FOS FYN	5.12e-05	178	51	4	be777ebef8f09a1a16fcee8fc69a65ab295b6e1d
ToppCell	facs-Pancreas-Exocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGFR3 FYN ANGPTL1 WWC1	5.23e-05	179	51	4	bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	SYNJ1 FOS ASTN2 SORBS1	5.23e-05	179	51	4	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPP4 PDE4D ANK3 FOS	5.23e-05	179	51	4	b0585a8e596c3d8e434af943e65207fa5877600d
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPP4 PDE4D ANK3 FOS	5.35e-05	180	51	4	05f14cd367021891166825a8aac171227e2bcd97
ToppCell	facs-Lung-EPCAM-18m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 C1orf54 ADCY4 SORBS1	5.35e-05	180	51	4	082c6116e0bbba8d9a3a82d14af55bdc8990c8c0
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 C1orf54 ADCY4 SORBS1	5.35e-05	180	51	4	53043d764fad9ac33ee40e356e562e759931adef
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	RASGEF1B FGFR3 USH2A CUX1	5.46e-05	181	51	4	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	Healthy_donor-MAIT\|Healthy_donor / disease group, cell group and cell class (v2)	DPP4 PDE4D BCAS2 FOS	5.58e-05	182	51	4	ac7c83464487ecde3df6804a99551307bd768f21
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 C1orf54 FOS MTSS1	5.58e-05	182	51	4	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MTSS1 RASGEF1B ANGPTL1 BANK1	5.58e-05	182	51	4	ccd729388d997cc45071175cb0c3db6d0790eaf8
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 AMOTL1 PIGG F8	5.70e-05	183	51	4	709a486154b3157427deb3b8886b63ac39ea42dd
ToppCell	droplet-Liver-nan-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 AMOTL1 PIGG F8	5.70e-05	183	51	4	dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell	COVID-19-Epithelial_cells-ECM-high_epithelial\|COVID-19 / group, cell type (main and fine annotations)	PDE4D ANK3 SORBS1 WWC1	5.70e-05	183	51	4	dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	DPP4 PDE4D ANK3 WWC1	5.82e-05	184	51	4	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	ILEUM-inflamed-(1)_T_cell-(1)_CD8_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PDE4D FOS RASGEF1B FYN	5.82e-05	184	51	4	cef3ee2a4a0af961aa3b4c92150d423e841ae8c1
ToppCell	facs-Marrow-T-cells-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RRAS2 MTSS1 FYN BANK1	5.95e-05	185	51	4	e1fd0a807def8c2127194108b1a30c6de7024292
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPP4 PDE4D ANK3 FOS	6.20e-05	187	51	4	e1d6c1194476cf26969e405b0951796fed519f44
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	PDE4D ANK3 SORBS1 TEX14	6.20e-05	187	51	4	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RRAS2 MTSS1 ANGPTL1 BANK1	6.20e-05	187	51	4	d01926be1c8846a25fb6706e26b56b808b69f8f0
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	PDE4D ANK3 PSD3 FGFR3	6.20e-05	187	51	4	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPP4 PDE4D ANK3 FOS	6.33e-05	188	51	4	3e3055dacc05a932f2beb114babf1dc76994e1af
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	ADCY4 BCAS2 FYN F8	6.33e-05	188	51	4	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RRAS2 MTSS1 ANGPTL1 BANK1	6.33e-05	188	51	4	d8decd9b5967873ca8320c2f9f07365f163c777f
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PDE4D ANK3 FGF13 FYN	6.33e-05	188	51	4	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	DPP4 PDE4D ANK3 WWC1	6.46e-05	189	51	4	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FOS MTSS1 RASGEF1B BANK1	6.46e-05	189	51	4	b13f315f617840eb5143a4e8a33a657c20365c21
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	PDE4D ANK3 PSD3 SORBS1	6.46e-05	189	51	4	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPP4 PLXNA4 ASTN2 WWC1	6.59e-05	190	51	4	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAP4K3 MTSS1 RASGEF1B BANK1	6.59e-05	190	51	4	ed100e271aac82806f59e0c613ccda63f59100c1
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DPP4 PDE4D ANK3 FYN	6.59e-05	190	51	4	55df73c8b696967a925b1772631f6900eff0fa30
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RRAS2 MTSS1 ANGPTL1 BANK1	6.59e-05	190	51	4	112706d64ee73b55dcf76f33ca064ab1fc6ce87f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARFGAP3 ASTN2 FGF13 WWC1	6.59e-05	190	51	4	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARFGAP3 ASTN2 FGF13 WWC1	6.59e-05	190	51	4	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RRAS2 PDE4D CUX1 WWC1	6.59e-05	190	51	4	989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPP4 PDE4D ANK3 WWC1	6.59e-05	190	51	4	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPP4 PLXNA4 ASTN2 WWC1	6.59e-05	190	51	4	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DPP4 PDE4D ANK3 FYN	6.59e-05	190	51	4	494fbab37305a7f92cddec75b291d42282555f5f
ToppCell	(0)_Normal/No_Treatment-(1)_VE-Cad+_vascular_cells\|World / Stress and Cell class	FOS RASGEF1B PLOD1 F8	6.59e-05	190	51	4	ff083168d609957d00888f31b3488d6d56c902b4
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOS MTSS1 RASGEF1B BANK1	6.59e-05	190	51	4	ee7b60cdf93c695ea2d59a170ca8cf4dc93e7eb2
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RRAS2 MTSS1 ANGPTL1 BANK1	6.73e-05	191	51	4	a831e30f37aff329d83fac9bdb84f783075d5df6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FOS ASTN2 FGF13 WWC1	6.73e-05	191	51	4	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPP4 PDE4D ANK3 FOS	6.73e-05	191	51	4	b53b490a8796e819edd3eb4a5a42b4499077b2d3
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	DPP4 PDE4D ANK3 WWC1	6.73e-05	191	51	4	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RRAS2 MTSS1 ANGPTL1 BANK1	6.73e-05	191	51	4	2453064c39b359088d43d52792bf829f83442c82
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RRAS2 MTSS1 ANGPTL1 BANK1	6.87e-05	192	51	4	446c61c0d6ba89c619efe87ee495951299953981
ToppCell	COVID-19-kidney-CNT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDE4D ANK3 FGF13 WWC1	6.87e-05	192	51	4	760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCell	CF-Myeloid-Monocyte\|Myeloid / Disease state, Lineage and Cell class	MAP4K3 MTSS1 RASGEF1B FYN	6.87e-05	192	51	4	da55719454b800b7e0cd6d5afd6332ecc5553218
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D ANK3 FGF13 CUX1	6.87e-05	192	51	4	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP91 ANK3 MTSS1 DNAH6	7.01e-05	193	51	4	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE4D MTSS1 ANGPTL1 BANK1	7.01e-05	193	51	4	de0213f2105b814f38ffbfd004ea7603230eed68
ToppCell	facs-Liver-Non-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 FOS FYN F8	7.01e-05	193	51	4	8084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell	CF-Myeloid-Monocyte\|CF / Disease state, Lineage and Cell class	MAP4K3 MTSS1 RASGEF1B FYN	7.01e-05	193	51	4	3a83b2593a37a075f91354745e5a7a081ec406a8
ToppCell	Control-Myeloid-Macrophage\|Myeloid / Disease state, Lineage and Cell class	PDE4D FOS MTSS1 DNAH6	7.01e-05	193	51	4	2a6d531abd34df20941cf3dac4fdfb1621a1bde6
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOS RPS6KA1 PLOD1 BANK1	7.15e-05	194	51	4	2224c7c943cfd5c1a329dfcf19d6e5ef8c49d85d
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOS RPS6KA1 PLOD1 BANK1	7.15e-05	194	51	4	50c5fc349533281a426bc7227a8ea9eca8d11985
ToppCell	ILEUM-inflamed-(1)_Trm\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DPP4 PDE4D FOS FYN	7.15e-05	194	51	4	cf22bd6afe51c42cb151c37a8b65c98649dae1a4
ToppCell	COVID-19_Moderate-B_naive\|COVID-19_Moderate / disease group, cell group and cell class	RRAS2 MTSS1 ANGPTL1 BANK1	7.15e-05	194	51	4	8c41a37467bfd4966ecd09dde68c543dc01b6ad0
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADCY4 SORBS1 FYN F8	7.15e-05	194	51	4	71ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D ANK3 ASTN2 WWC1	7.15e-05	194	51	4	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D ANK3 ASTN2 WWC1	7.15e-05	194	51	4	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	severe_influenza-Non-classical_Monocyte\|severe_influenza / disease group, cell group and cell class (v2)	RASL11A MTSS1 RASGEF1B RRAS	7.15e-05	194	51	4	7630e223666fb65743e21e045478f687dd739a54
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D ANK3 ASTN2 WWC1	7.15e-05	194	51	4	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	ANK3 PSD3 ASTN2 SORBS1	7.15e-05	194	51	4	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	COVID-19_Moderate-B_naive\|World / disease group, cell group and cell class	RRAS2 MTSS1 ANGPTL1 BANK1	7.15e-05	194	51	4	1f81d618799e482a36dce528bba70f52cc69a901
ToppCell	COVID-19_Severe-B_naive\|World / disease group, cell group and cell class	RRAS2 MTSS1 ANGPTL1 BANK1	7.15e-05	194	51	4	d363963a6caeedf4f9e9ad22dcf9b66b85c79a48
ToppCell	COVID-19-kidney-Glomerular_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MTSS1 SORBS1 FYN F8	7.15e-05	194	51	4	660535b492445063d965095a50e1e299ce04c50a
ToppCell	facs-Brain_Myeloid-Cortex-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOS RPS6KA1 PLOD1 BANK1	7.15e-05	194	51	4	1662b110f84584e75150df0ac970e7df82f26e7e
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	ANK3 PSD3 ASTN2 SORBS1	7.15e-05	194	51	4	c3535f7cc0076653c72db582047cff053c322397
ToppCell	Non-neuronal-Non-dividing-Radial_Glia\|World / Primary Cells by Cluster	FOS CSPG5 FGFR3 ANGPTL1	7.15e-05	194	51	4	1445b7611c2b1ab9b320f330d17d70117892cc28
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOS RPS6KA1 PLOD1 BANK1	7.15e-05	194	51	4	b31d6361fa939a92a4a3dc63c209ecd3eb514e6a
Disease	Squamous cell carcinoma of lung	GUCY2F MAP4K3 PRKDC FYN	2.75e-07	32	51	4	C0149782
Disease	Costello syndrome (implicated_via_orthology)	RRAS2 RRAS	8.78e-06	3	51	2	DOID:0050469 (implicated_via_orthology)
Disease	Amphetamine-Related Disorders	PDE4D FOS PSD3 ASTN2	8.79e-06	75	51	4	C0236733
Disease	Amphetamine Abuse	PDE4D FOS PSD3 ASTN2	8.79e-06	75	51	4	C0236807
Disease	Amphetamine Addiction	PDE4D FOS PSD3 ASTN2	8.79e-06	75	51	4	C0236804
Disease	cortical surface area measurement	DPP4 RRAS2 ANK3 RASGEF1B ASTN2 FGFR3 ARHGAP27 BANK1 CUX1 WWC1 STRIP1	1.50e-05	1345	51	11	EFO_0010736
Disease	Alcohol Related Neurodevelopmental Disorder	ANK3 RPS6KA1	2.92e-05	5	51	2	C0814154
Disease	Partial Fetal Alcohol Syndrome	ANK3 RPS6KA1	2.92e-05	5	51	2	C3661483
Disease	Alcohol Related Birth Defect	ANK3 RPS6KA1	4.37e-05	6	51	2	C3146244
Disease	Malignant neoplasm of breast	GUCY2F ARFGAP3 FOS HLCS ASTN2 SORBS1 PLOD1 SUV39H2 CUX1	8.33e-05	1074	51	9	C0006142
Disease	RASopathy (implicated_via_orthology)	RRAS2 RRAS	1.05e-04	9	51	2	DOID:0080690 (implicated_via_orthology)
Disease	urinary bladder cancer (implicated_via_orthology)	RRAS2 RRAS	1.05e-04	9	51	2	DOID:11054 (implicated_via_orthology)
Disease	cognitive function measurement	PDE4D MTSS1 PLXNA4 PSD3 FGF13 TEX14 RRAS FYN USH2A STRIP1	1.47e-04	1434	51	10	EFO_0008354
Disease	Fetal Alcohol Spectrum Disorders	ANK3 RPS6KA1	2.26e-04	13	51	2	C2985290
Disease	mitochondrial DNA measurement	RRAS2 PDE4D RASL11A BANK1 CUX1	2.54e-04	328	51	5	EFO_0006312
Disease	retinal vasculature measurement	C1orf54 PDE4D RASGEF1B PSD3 FGFR3 STRIP1	2.59e-04	517	51	6	EFO_0010554
Disease	Fetal Alcohol Syndrome	ANK3 RPS6KA1	3.92e-04	17	51	2	C0015923
Disease	Juvenile Myelomonocytic Leukemia	RRAS2 RRAS	4.92e-04	19	51	2	C0349639
Disease	osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty	FGFR3 CUX1	6.02e-04	21	51	2	EFO_0004616, EFO_0010726, EFO_1000786
Disease	cerebellar cortex volume measurement	CUX1 WWC1	6.02e-04	21	51	2	EFO_0010291
Disease	Adenocarcinoma of large intestine	FGFR3 PRKDC CUX1	6.21e-04	96	51	3	C1319315
Disease	Noonan Syndrome	RRAS2 RRAS	7.89e-04	24	51	2	C0028326
Disease	immature platelet fraction	PSD3 SORBS1 CUX1	1.02e-03	114	51	3	EFO_0009187
Disease	blood nickel measurement	PDE4D USH2A WWC1	1.18e-03	120	51	3	EFO_0007583
Disease	alcohol consumption measurement	DPP4 PLXNA4 ASTN2 ARHGAP27 SGF29 BANK1 CUX1 WWC1	1.22e-03	1242	51	8	EFO_0007878
Disease	Carcinoma, Ovarian Epithelial	RRAS2 FOS	1.24e-03	30	51	2	C4721610
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	FOS MTSS1 RASGEF1B	1.52e-03	131	51	3	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	FOS MTSS1 RASGEF1B	1.52e-03	131	51	3	C4552091
Disease	Juvenile arthritis	FOS MTSS1 RASGEF1B	1.52e-03	131	51	3	C3495559
Disease	Juvenile psoriatic arthritis	FOS MTSS1 RASGEF1B	1.52e-03	131	51	3	C3714758
Disease	Juvenile-Onset Still Disease	FOS MTSS1 RASGEF1B	1.66e-03	135	51	3	C0087031
Disease	hippocampus molecular layer volume	DPP4 ASTN2	1.68e-03	35	51	2	EFO_0009397

Protein segments in the cluster

Peptide	Gene	Start	Entry
YEEDIASFSTYIPST	BANK1	416	Q8NDB2
DDSYFTSSSSYFDEP	ARFGAP3	346	Q9NP61
DFTPFDESDFYPTTS	CSPG5	256	O95196
DESDFYPTTSFYDDL	CSPG5	261	O95196
PSEDLFYETYYSLSQ	ADCY4	11	Q8NFM4
VLEDSTYFSPDFQLY	AMOTL1	31	Q8IY63
AEYSSFRLEPESEFY	ANGPTL1	381	O95841
SYSSDYIYLFDPKDD	DCAF6	271	Q58WW2
SGSPYLDLSLFSYDD	DET1	456	Q7L5Y6
YTDTDLYTGEFLSFA	ASTN2	1111	O75129
AYDFLYDPLFIVSSE	CFAP91	36	Q7Z4T9
DGFLDSSEEIYYTAR	MAP4K3	356	Q8IVH8
AYTSSFVFTYPEADS	FOS	336	P01100
SFTDLYYDPFEQLDS	WWC1	461	Q8IX03
LPYDYSSSLESVADE	HLCS	131	P50747
YSSQYEERLDPFSSF	CUX1	571	Q13948
SDTFTIIPDFDIYYV	PLXNA4	231	Q9HCM2
SYEDTLDLEEDPYFT	FHIP2B	491	Q86V87
EDTIPSQVSDYDYFS	MTSS1	516	O43312
FLYRSDSDYDLSPKS	PDE4D	191	Q08499
TEVPLIEYSFYSDES	DPP4	231	P27487
PYSFYSSLISYEEDQ	F8	1801	P00451
PVFSEDALYLASYES	RASGEF1B	436	Q0VAM2
TYYFSVDADVALTEP	PLOD1	376	Q02809
DFSIRTYTYADTPDD	GBA	166	P04062
ASEYPIFEKFSSYDT	DNAJB7	141	Q7Z6W7
FFSPETLEEDYKYSE	DNAH6	3771	Q9C0G6
EFFRPYELSSFDDTF	FIG4	676	Q92562
PTFEYLQSFLEDYFT	FYN	511	P06241
DPSFDLSYSFEYVIL	GUCY2F	86	P51841
PDTYFSYKVDEEFAT	ANK3	3516	Q12955
NSEGYLYTSELFTPE	FGF13	126	Q92913
STDEYLDLSAPFEQY	FGFR3	756	P22607
SFYTYLTFLDPDCDE	PHKA2	611	P46019
KEDTFFYSLVYDPSL	MTA3	126	Q9BTC8
AEGFLLVYSITDYDS	RASL11A	106	Q6T310
FNYTDEELLPFSTYS	USH2A	4316	O75445
SFIDSELLPFTEYEY	USH2A	4696	O75445
DEFLTPDGEYFYSST	TEX14	1081	Q8IWB6
APTYKYDLFSDDYDT	SYNJ1	781	O43426
TDYPESLTSYPEEDY	ARHGAP27	361	Q6ZUM4
ELSELYSYTEGPEFL	STRIP1	81	Q5VSL9
QSYFVTDYDPTIEDS	RRAS2	36	P62070
SYLTAPDYSAFETDI	BCAS2	51	O75934
PSYDDFSADFTIDYS	C1orf54	41	Q8WWF1
FSDVDSPYYDLDTVL	CDCA4	181	Q9BXL8
PQDDYSVLFEDTSYA	SGF29	256	Q96ES7
GITYLFDLDYESDEF	SUV39H2	301	Q9H5I1
DSDLYSPRYSFSEDT	SORBS1	456	Q9BX66
YPFIISSESYSFKDT	PRKDC	3531	P78527
EYDGTTSFFVSDYTE	PIGG	176	Q5H8A4
QSYFVSDYDPTIEDS	RRAS	51	P10301
YSAESLETLYSEPDS	PSD3	456	Q9NYI0
LETLYSEPDSYFSFE	PSD3	461	Q9NYI0
DDTFYFDTEFTSRTP	RPS6KA1	346	Q15418