Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium channel inhibitor activity

NEDD4L PCSK9

1.14e-048412GO:0019871
GeneOntologyCellularComponentglutamatergic synapse

CACNB4 NEO1 PPFIA3 NEDD4L SLC30A3 SYT17 PLXNA1 LPA

1.60e-04817418GO:0098978
GeneOntologyCellularComponentmicrovesicle

PPFIA3 SLC30A3

2.04e-0411412GO:1990742
DomainNeogenin_C

NEO1 DCC

4.70e-062412IPR010560
DomainNeogenin_C

NEO1 DCC

4.70e-062412PF06583
DomainHECT

NEDD4L WWP1

1.59e-0327412PF00632
DomainHECTc

NEDD4L WWP1

1.59e-0327412SM00119
DomainHECT_dom

NEDD4L WWP1

1.59e-0327412IPR000569
DomainHECT

NEDD4L WWP1

1.59e-0327412PS50237
DomainC2

NEDD4L SYT17 WWP1

2.96e-03131413PF00168
DomainC2

NEDD4L SYT17 WWP1

3.36e-03137413SM00239
DomainC2

NEDD4L SYT17 WWP1

3.71e-03142413PS50004
Domain-

NEDD4L SYT17 WWP1

4.17e-031484132.60.40.150
DomainWW

NEDD4L WWP1

4.77e-0347412PF00397
DomainWW

NEDD4L WWP1

4.98e-0348412SM00456
DomainC2_dom

NEDD4L SYT17 WWP1

5.55e-03164413IPR000008
DomainWW_DOMAIN_2

NEDD4L WWP1

5.60e-0351412PS50020
DomainWW_DOMAIN_1

NEDD4L WWP1

5.60e-0351412PS01159
DomainWW_dom

NEDD4L WWP1

5.82e-0352412IPR001202
DomainIg_I-set

NEO1 DCC HMCN1

8.32e-03190413IPR013098
DomainI-set

NEO1 DCC HMCN1

8.32e-03190413PF07679
Pubmed

Association between lipoprotein (a) and proprotein convertase substilisin/kexin type 9 in patients with heterozygous familial hypercholesterolemia: A case-control study.

LPA PCSK9

1.36e-06241229129821
Pubmed

Lipoprotein(a) in Familial Hypercholesterolemia With Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Gain-of-Function Mutations.

LPA PCSK9

1.36e-06241226632531
Pubmed

PCSK9 and Lp(a) levels of children born after assisted reproduction technologies.

LPA PCSK9

1.36e-06241231079266
Pubmed

Plasma proprotein convertase subtilisin/kexin type 9 is associated with Lp(a) in type 2 diabetic patients.

LPA PCSK9

1.36e-06241226412029
Pubmed

Apolipoprotein(a) phenotype determines the correlations of lipoprotein(a) and proprotein convertase subtilisin/kexin type 9 levels in patients with potential familial hypercholesterolemia.

LPA PCSK9

1.36e-06241230270088
Pubmed

Selective depletion of tumour suppressors Deleted in Colorectal Cancer (DCC) and neogenin by environmental and endogenous serine proteases: linking diet and cancer.

NEO1 DCC

1.36e-06241227716118
Pubmed

Endogenous estrogens lower plasma PCSK9 and LDL cholesterol but not Lp(a) or bile acid synthesis in women.

LPA PCSK9

1.36e-06241222207727
Pubmed

The different relations of PCSK9 and Lp(a) to the presence and severity of atherosclerotic lesions in patients with familial hypercholesterolemia.

LPA PCSK9

1.36e-06241230170223
Pubmed

PCSK9 inhibition-mediated reduction in Lp(a) with evolocumab: an analysis of 10 clinical trials and the LDL receptor's role.

LPA PCSK9

4.06e-06341227102113
Pubmed

Circulating levels of PCSK9, ANGPTL3 and Lp(a) in stage III breast cancers.

LPA PCSK9

4.06e-06341236203122
Pubmed

Differential regulation of myosin X movements by its cargos, DCC and neogenin.

NEO1 DCC

4.06e-06341222349703
Pubmed

Alternative splicing determines the domain structure of WWP1, a Nedd4 family protein.

NEDD4L WWP1

4.06e-06341211779188
Pubmed

The spatial and temporal expression patterns of netrin receptors, DCC and neogenin, in the developing mouse retina.

NEO1 DCC

4.06e-06341210843775
Pubmed

Lipoprotein(a) catabolism is regulated by proprotein convertase subtilisin/kexin type 9 through the low density lipoprotein receptor.

LPA PCSK9

4.06e-06341225778403
Pubmed

The transcription factor gene Nfib is essential for both lung maturation and brain development.

NEO1 DCC NFIB

6.04e-063041315632069
Pubmed

The expression patterns of guidance receptors, DCC and Neogenin, are spatially and temporally distinct throughout mouse embryogenesis.

NEO1 DCC

8.12e-0644129441666
Pubmed

Focal adhesion kinase in netrin-1 signaling.

NEO1 DCC

8.12e-06441215494733
Pubmed

Myosin X regulates netrin receptors and functions in axonal path-finding.

NEO1 DCC

8.12e-06441217237772
Pubmed

Different levels of the Tripartite motif protein, Anomalies in sensory axon patterning (Asap), regulate distinct axonal projections of Drosophila sensory neurons.

NEO1 DCC

8.12e-06441222084112
Pubmed

The Ubiquitin Ligase Itch and Ubiquitination Regulate BFRF1-Mediated Nuclear Envelope Modification for Epstein-Barr Virus Maturation.

NEDD4L WWP1

8.12e-06441227466427
Pubmed

Phosphatidylinositol transfer protein-alpha in netrin-1-induced PLC signalling and neurite outgrowth.

NEO1 DCC

8.12e-06441216244667
Pubmed

Motor axon guidance of the mammalian trochlear and phrenic nerves: dependence on the netrin receptor Unc5c and modifier loci.

NEO1 DCC

8.12e-06441216723533
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

CEP170 LIMA1 KIF26B DYNC1H1 DENND4C

1.25e-0525641533397691
Pubmed

Netrin 1 acts as an attractive or as a repulsive cue for distinct migrating neurons during the development of the cerebellar system.

NEO1 DCC

1.35e-05541210704383
Pubmed

Developmentally regulated expression of Netrin-1 and -3 in the embryonic mouse molar tooth germ.

NEO1 DCC

1.35e-05541212889066
Pubmed

A Nedd4 E3 Ubiquitin Ligase Pathway Inhibits Robo1 Repulsion and Promotes Commissural Axon Guidance across the Midline.

NEDD4L WWP1

1.35e-05541236002265
Pubmed

Identification of new partners of the epithelial sodium channel alpha subunit.

NEDD4L WWP1

1.35e-05541214556380
Pubmed

Netrin-1 promotes thalamic axon growth and is required for proper development of the thalamocortical projection.

NEO1 DCC

2.03e-05641210908620
Pubmed

Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.

NEO1 DCC

2.03e-05641224876346
Pubmed

Genetic analysis of DSCAM's role as a Netrin-1 receptor in vertebrates.

NEO1 DCC

2.03e-05641222238077
Pubmed

Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling.

NEO1 DCC

2.03e-05641233740419
Pubmed

Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.

NEDD4L WWP1

2.03e-05641228461335
Pubmed

FoxO3 transcription factor and Sirt6 deacetylase regulate low density lipoprotein (LDL)-cholesterol homeostasis via control of the proprotein convertase subtilisin/kexin type 9 (Pcsk9) gene expression.

FOXO4 PCSK9

2.03e-05641223974119
Pubmed

Defects in neural guidepost structures and failure to remove leptomeningeal cells from the septal midline behind the interhemispheric fusion defects in Netrin1 deficient mice.

NEO1 DCC

2.84e-05741226397040
Pubmed

Transmembrane adaptor protein WBP1L regulates CXCR4 signalling and murine haematopoiesis.

NEDD4L WWP1

2.84e-05741231845480
Pubmed

Rb/E2F regulates expression of neogenin during neuronal migration.

NEO1 DCC

2.84e-05741221059867
Pubmed

Cloning of three mouse Unc5 genes and their expression patterns at mid-gestation.

NEO1 DCC

2.84e-05741212351186
Pubmed

PlexinA1 is crucial for the midline crossing of callosal axons during corpus callosum development in BALB/cAJ mice.

DCC PLXNA1

2.84e-05741231430342
Pubmed

Netrins and DCC in the guidance of migrating neural crest-derived cells in the developing bowel and pancreas.

NEO1 DCC

2.84e-05741212798294
Pubmed

A screen for downstream effectors of Neurogenin2 in the embryonic neocortex.

MARCHF7 DCC NFIB

3.23e-055241315328020
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CEP170 CACNB4 LIMA1 PPFIA3 NEDD4L ARHGEF17 INF2 KCND3 DYNC1H1

3.51e-05143141937142655
Pubmed

Floor plate and netrin-1 are involved in the migration and survival of inferior olivary neurons.

NEO1 DCC

3.78e-05841210341242
Pubmed

Tagging genes with cassette-exchange sites.

LIMA1 KAT6B XPO5 NFIB PLXNA1

4.54e-0533541515741177
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CEP170 CACNB4 NEO1 PPFIA3 NEDD4L KCND3 AKAP8L TNRC6A

4.72e-05113941836417873
Pubmed

Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.

PGLYRP2 DCC LPA

5.48e-056241317975119
Pubmed

Gene variants associated with ischemic stroke: the cardiovascular health study.

PGLYRP2 DCC LPA

5.75e-056341319023099
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CEP170 FOXO4 LIMA1 NEDD4L ARHGEF17 KIF26B DENND4C

6.00e-0586141736931259
Pubmed

Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog.

NEDD4L WWP1

6.07e-051041225092867
Pubmed

Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.

LPA PCSK9

6.07e-051041222331829
Pubmed

Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis.

NEO1 DCC

7.41e-051141215186747
Pubmed

Analysis of Netrin 1 receptors during inner ear development.

NEO1 DCC

7.41e-051141217616930
Pubmed

USP11 augments TGFβ signalling by deubiquitylating ALK5.

NEDD4L WWP1

7.41e-051141222773947
Pubmed

Netrin-1 Confines Rhombic Lip-Derived Neurons to the CNS.

NEO1 DCC

7.41e-051141229444422
Pubmed

Dysregulated Inflammatory Signaling upon Charcot-Marie-Tooth Type 1C Mutation of SIMPLE Protein.

NEDD4L WWP1

7.41e-051141225963657
Pubmed

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.

CEP170 LIMA1 DYNC1H1 WWP1

7.46e-0519041415161933
Pubmed

Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR).

MARCHF7 PJA1

8.88e-051241222544753
Pubmed

Complete Loss of Netrin-1 Results in Embryonic Lethality and Severe Axon Guidance Defects without Increased Neural Cell Death.

NEO1 DCC

1.05e-041341226257176
Pubmed

gdnf activates midline repulsion by Semaphorin3B via NCAM during commissural axon guidance.

DCC PLXNA1

1.05e-041341222998873
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

XPO5 AKAP8L DYNC1H1 HASPIN

1.12e-0421141417314511
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CEP170 CACNB4 LIMA1 QSER1 PPFIA3 NEDD4L DYNC1H1

1.21e-0496341728671696
Pubmed

K27-linked ubiquitination of BRAF by ITCH engages cytokine response to maintain MEK-ERK signaling.

NEDD4L WWP1

1.22e-041441231015455
Pubmed

A midline switch of receptor processing regulates commissural axon guidance in vertebrates.

DCC PLXNA1

1.22e-041441220159958
Pubmed

Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A.

CEP170 XPO5 DYNC1H1

1.26e-048241330274258
Pubmed

Phenotypic analysis of mice completely lacking netrin 1.

NEO1 DCC

1.41e-041541226395479
Pubmed

Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice.

DCC NFIB

1.41e-041541219961580
Pubmed

SYT14L, especially its C2 domain, is involved in regulating melanocyte differentiation.

NEDD4L SYT17

1.41e-041541223999003
Pubmed

NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord.

NEO1 DCC

1.61e-041641227223328
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CEP170 LIMA1 AKAP8L DENND4C TNRC6A

1.74e-0444641524255178
Pubmed

RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling.

NEDD4L WWP1

1.82e-041741228292929
Pubmed

Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping.

DCC NEDD4L

1.82e-041741219690890
Pubmed

Analysis of Expression Pattern and Genetic Deletion of Netrin5 in the Developing Mouse.

NEO1 DCC

1.82e-041741226858598
Pubmed

Global landscape of HIV-human protein complexes.

CEP170 NEDD4L XPO5 AKAP8L DYNC1H1

1.94e-0445741522190034
Pubmed

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses.

LPA PCSK9

2.05e-041841220971364
Pubmed

Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.

LPA PCSK9

2.05e-041841223726366
Pubmed

SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.

NEDD4L WWP1

2.29e-041941221572392
Pubmed

Identification of novel spartin-interactors shows spartin is a multifunctional protein.

DYNC1H1 WWP1

2.29e-041941219765186
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

KAT6B ARHGEF17 DYNC1H1

2.55e-041044139205841
Pubmed

DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation.

DCC NFIB

2.81e-042141233871356
Pubmed

In silico QTL mapping of basal liver iron levels in inbred mouse strains.

ABCC12 LPA

2.81e-042141221062905
Pubmed

Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.

NEDD4L WWP1

2.81e-042141237005481
Pubmed

ARRDC1 and ARRDC3 act as tumor suppressors in renal cell carcinoma by facilitating YAP1 degradation.

NEDD4L WWP1

2.81e-042141229416926
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CEP170 QSER1 NEDD4L KAT6B INF2 KCND3 NFIB WWP1

2.99e-04148941828611215
Pubmed

Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.

NEO1 DCC

3.09e-042241222726835
Pubmed

USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.

NEDD4L WWP1

3.09e-042241224850914
Pubmed

Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex.

NEO1 DCC

3.38e-042341226659141
Pubmed

Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons.

NEO1 DCC

3.68e-042441226633881
Pubmed

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

LIMA1 XPO5 DYNC1H1

3.69e-0411841327377895
Pubmed

Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.

NEDD4L WWP1

4.00e-042541223873930
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

LIMA1 INF2 DYNC1H1 DENND4C

4.17e-0429841430737378
Pubmed

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

NEDD4L WWP1

4.33e-042641226949039
Pubmed

Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development.

NEO1 DCC

5.78e-043041232562661
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

CEP170 LIMA1 CDX4 INF2 DYNC1H1

8.16e-0462641533644029
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

NEDD4L NFIB DYNC1H1 WWP1

8.28e-0435841432460013
Pubmed

Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice.

MARCHF7 NFIB

8.33e-043641215745951
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

CEP170 LIMA1 AKAP8L DYNC1H1

8.45e-0436041433111431
Pubmed

Ion channel expression in the developing enteric nervous system.

CACNB4 KCND3

8.80e-043741225798587
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPV6 CACNB4

9.28e-043841230786075
Pubmed

140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.

PPFIA3 PLXNA1 DYNC1H1

9.45e-0416341316512683
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

MUC16 LIMA1 TNRC6A

1.07e-0317041323314748
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

LIMA1 NEU1 DCC AKAP8L DYNC1H1

1.10e-0367041522990118
CytobandEnsembl 112 genes in cytogenetic band chrXq13

FOXO4 CDX4 PJA1

4.40e-04165413chrXq13
CytobandXq13.1

FOXO4 PJA1

8.55e-0448412Xq13.1
Cytoband19p13.12

PGLYRP2 AKAP8L

9.28e-045041219p13.12
CytobandEnsembl 112 genes in cytogenetic band chr9p22

NFIB DENND4C

1.04e-0353412chr9p22
Cytoband1q44

CEP170 KIF26B

4.39e-031104121q44
CytobandEnsembl 112 genes in cytogenetic band chr19p13

MUC16 PGLYRP2 TMEM221 AKAP8L

5.49e-03797414chr19p13
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn|World / Primary Cells by Cluster

CEP170 DCC NEDD4L KIF26B NFIB

9.84e-071964159401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Neuron|2m / Sample Type, Dataset, Time_group, and Cell type.

CEP170 DCC NEDD4L KAT6B NFIB

1.09e-06200415a581f1704a87b0390e1e2ff85053367d85247755
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MUC16 TRPV6 TMEM221 KCND3

1.27e-05156414605d95a900e1443d3f6aae163ef2e893d3293203
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MUC16 TRPV6 TMEM221 KCND3

1.27e-05156414574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 NEDD4L ITPRID1 SYT17

1.75e-051694142a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 ABCC12 ITPRID1 SLC30A3

1.91e-05173414ee972d9cc68755926512fd3bbe1267098c67cd94
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 NEDD4L ITPRID1 SYT17

1.91e-051734140bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCC12 ITPRID1 SLC30A3 SYT17

1.96e-051744142947e5906b172d149412fa4e77476fce4ea695d2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-31|World / Primary Cells by Cluster

DCC ITPRID1 KIF26B NFIB

2.00e-05175414491508bf9e8a09b057d5711cc23dd91324e6a806
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL5 LIMA1 HMCN1 NFIB

2.54e-0518641441f1674afc17661eccaa779cdeb663db5e45685d
ToppCelldroplet-Lung-LUNG-30m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL5 LIMA1 HMCN1 NFIB

2.54e-05186414aa006650cf21a2c51dfe1091681f67fdad939107
ToppCellNS-critical-d_0-4-Epithelial-Basal|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PJA1 PPFIA3 SYT17 WWP1

2.94e-051934141affb4c2e21712bde0d36ab736411fe36642cc6d
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC16 ABCC12 CACNB4 HMCN1

3.06e-05195414d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC16 ABCC12 CACNB4 HMCN1

3.06e-0519541419853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 KLHL5 NEDD4L ITPRID1

3.24e-05198414fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCellSepsis-ICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, condition lineage and cell class

SPPL3 LIMA1 INF2 AKAP8L

3.31e-0519941490ddd686b8f39c6f6134b9b048396cebcf8d0448
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 CACNB4 NEDD4L ITPRID1

3.37e-052004140eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCC12 DCC ITPRID1

1.62e-04115413207d464c09caf9be361daa56c83cd7da5cf9ce47
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LIMA1 HMCN1 NFIB

2.02e-0412441336dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB4 ITPRID1 SYT17

3.19e-041454139964d6d3769be2f35d86268fe044cecd1d5a1616
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 ITPRID1 SYT17

3.74e-041534130a4fbe46125b05ee235deb528855808c2bf33cba
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Col27a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DCC ITPRID1 INF2

3.81e-04154413d22902d2922784583f7016453768ed05b14b965e
ToppCellAdult-Epithelial-basal_cell-D122|Adult / Lineage, Cell type, age group and donor

TRPV6 HMCN1 LPA

3.81e-0415441338d346402417960044ae999e61f0092b46f2b591
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

DCC NFIB PLXNA1

3.96e-041564137e6805ebc7bc2f9c5965321d16922c155719970f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like-IPs_and_early_cortical_neurons|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

DCC NFIB PLXNA1

3.96e-04156413741de05295b2d012ac8576378f37709a97c8fb50
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPV6 CACNB4 HMCN1

4.11e-041584137960337d87afecf2692ab65e5991f052ceddfacc
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC12 DCC HMCN1

4.26e-04160413c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC12 DCC HMCN1

4.26e-0416041325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TRPV6 TMEM221 HMCN1

4.34e-04161413da9eecf919866a9c579d7a707a996cf335213134
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TRPV6 TMEM221 HMCN1

4.34e-04161413d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCelldroplet-Limb_Muscle-nan-18m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPPL3 CEP170 XPO5

4.42e-0416241371d7849108a1b59beff40e46000172c45a2f5439
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC12 DCC ARHGEF17

4.58e-04164413f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 NEDD4L SYT17

4.83e-04167413166b7b4ca0663cde6d88219ee0bcc1988d03dab8
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCC SLC30A3 SYT17

4.91e-041684131d58731a481ecac84c15affa84f8041dd67d944c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 NEDD4L SYT17

5.00e-041694134b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMA1 NEO1 WWP1

5.00e-04169413780fb0050852626062a729dd1b82b0cf61e7e9ca
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 NEDD4L SYT17

5.00e-04169413a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCC SLC30A3 SYT17

5.08e-0417041349fc45d8a5c3ad89d1649fa46d7a285891379392
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCC12 ITPRID1 SLC30A3

5.17e-041714136a489a75eeab2a2d48d604682e93599c20a945fe
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCC12 ITPRID1 SYT17

5.26e-0417241392e76cbf4807704790f42cf2507e92f85cd3bc92
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 FOXO4 PCSK9

5.44e-041744134da79da7a09ee1e345102c5331675ebcdbe56171
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MUC16 KIF26B PLXNA1

5.44e-041744139e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TRPV6 NEDD4L SYT17

5.44e-041744132cd6638b361ca05ab83d09ce657194aed97873b7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 NEDD4L SYT17

5.53e-0417541398947a226b5a2ac7091ff9d34243ea7736add973
ToppCellfacs-Skin-Anagen-24m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEO1 HMCN1 NFIB

5.53e-041754135552ff1e13f931c8cd7780726c90b5609497a648
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCC SLC30A3 SYT17

5.53e-04175413d4827b4dfad07f11cbdd47fbed287af1afb9b1b8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 NEDD4L SYT17

5.53e-0417541377c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MUC16 DCC HASPIN

5.62e-04176413dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 NEDD4L SYT17

5.62e-04176413c2c4306476989bc2fb30dab00250ef7915842f13
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 NEDD4L SYT17

5.72e-041774138e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPV6 CACNB4 HMCN1

5.72e-04177413c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCC12 ITPRID1 SLC30A3

5.72e-041774137e799333307448c6a94d1f33dbc59c543336f45e
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

FOXO4 KAT6B DYNC1H1

5.72e-04177413e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

LIMA1 QSER1 SLC30A3

5.81e-041784139a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEO1 XPO5 PLXNA1

5.81e-04178413c87945146b2734141f07b39d268e0d8086ee0364
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 ABCC12 ITPRID1

5.81e-04178413a48739a588f361b4bc69405d7e256c11f61cf43c
ToppCellMid-temporal_gyrus_(MTG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCC KCND3 PLXNA1

5.81e-04178413ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 NEDD4L SYT17

5.91e-04179413e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 ABCC12 SLC30A3

5.91e-04179413b35a7f8115c997c390201da01d7cb10b10769aec
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPV6 CACNB4 HMCN1

5.91e-04179413666072c0e8448dbaec1683d18368ec2502453f90
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 NEDD4L SYT17

5.91e-0417941327ad6a609fe1f7532b142d0147bccf918704a6dd
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 ABCC12 ITPRID1

6.00e-04180413b7513b9816a9cb9f3caaddb2a9fed0be1c7f9805
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 ABCC12 ITPRID1

6.00e-04180413f96c5be4705e3d338c0393d2885ac8d5beccd6fd
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

TRPV6 HMCN1 LPA

6.30e-0418341300a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPV6 CACNB4 HMCN1

6.30e-041834132f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellCOVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type

LIMA1 NEDD4L SYT17

6.30e-041834135c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 ABCC12 ITPRID1

6.30e-041834133ebe334ad570e3525341badb558f369c61daf3d3
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCC HMCN1 KIF26B

6.40e-04184413ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCC HMCN1 KIF26B

6.40e-041844132cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCC HMCN1 KIF26B

6.40e-041844132b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCC12 ITPRID1 SLC30A3

6.40e-041844139cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

MARCHF7 PJA1 DCC

6.50e-04185413857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

CACNB4 KCND3 NFIB

6.50e-04185413a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NEDD4L KIF26B NFIB

6.60e-04186413facc1bd8920003ad03d1893c32fc606d82b4d50a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCC KIF26B NFIB

6.60e-04186413b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LIMA1 NEDD4L SYT17

6.71e-041874137b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA3 SYT17 PLXNA1

6.71e-04187413e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA3 SYT17 PLXNA1

6.71e-0418741324cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL5 HMCN1 NFIB

6.71e-0418741352ffd4be374e329ac8d321063f061b826d252956
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA3 SYT17 PLXNA1

6.71e-041874132f153b203fe79f206319603cf94d3a03ab49a05d
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

KLHL5 NEDD4L ITPRID1

6.81e-041884131aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL5 TMEM221 HMCN1

6.92e-0418941316e019fd6e2376110b767739754389891f391669
ToppCelldroplet-Lung-LUNG-30m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL5 HMCN1 NFIB

6.92e-0418941325db316f66cee53774bb2b286cc457b37353356c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPV6 CACNB4 KIF26B

6.92e-041894138ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCC KIF26B NFIB

6.92e-041894133b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

NEO1 HMCN1 NFIB

6.92e-04189413dc5164591dea45b420798b94dda211be03daa70c
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLHL5 HMCN1 NFIB

7.02e-04190413d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPV6 NEDD4L KIF26B

7.02e-04190413c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPV6 CACNB4 KIF26B

7.02e-041904134836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL5 HMCN1 NFIB

7.02e-04190413e64b191f928935484e2c993d7f8af0572a617a3a
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

NEO1 HMCN1 NFIB

7.02e-041904131196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

MUC16 NEDD4L ITPRID1

7.02e-0419041351ca9ef4df3220487152fcf684147730637c7cc1
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPV6 NEDD4L KIF26B

7.02e-04190413d4910c37045a8b8bb53b37625263bc0a47b6e3f8
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

LIMA1 KAT6B SYT17

7.02e-04190413842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL5 TMEM221 HMCN1

7.13e-0419141338fe60a8570f3c6eb8e8f8646f90d505dfd7d647
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCC KIF26B NFIB

7.13e-041914131cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCC NEDD4L NFIB

7.13e-041914133c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCC NEDD4L NFIB

7.13e-041914131c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL5 TMEM221 HMCN1

7.13e-041914130e6cd2628a5cebd35e960e4eb3b52ddc9358031c
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNB4 LIMA1 NFIB

7.24e-041924138d56e360ebc624ca4cd7f0af4f3cc599c244f134
DrugNimodipine [66085-59-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A

TRPV6 QSER1 PPFIA3 ARHGEF17 KCND3 KIF26B NFIB AKAP8L

1.96e-091964186480_UP
Diseasenucleus accumbens volume change measurement

MUC16 ITPRID1

9.78e-0511402EFO_0021493
Diseaseresponse to statin, LDL cholesterol change measurement

LPA PCSK9

1.86e-0415402EFO_0007804, GO_0036273
Diseasechenodeoxycholate measurement

DCC HMCN1

1.86e-0415402EFO_0010471
Diseasecholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage

LPA PCSK9

3.70e-0421402EFO_0022246
Diseaseneuroimaging measurement

NEO1 QSER1 DCC KIF26B NFIB DENND4C TNRC6A

5.26e-041069407EFO_0004346
Diseasepolyunsaturated fatty acid measurement

NFIB LPA PCSK9

7.49e-04131403EFO_0010733
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

XPO5 INF2

7.61e-0430402C1868672
Diseasesporadic amyotrophic lateral sclerosis

ABCC12 NEDD4L PLXNA1

9.08e-04140403EFO_0001357
DiseaseVasodilators used in cardiac diseases use measurement

LPA PCSK9

9.78e-0434402EFO_0009926
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

LPA PCSK9

9.78e-0434402EFO_0008317, EFO_0008596, EFO_0020944
DiseaseC-reactive protein measurement

SPPL3 NEO1 QSER1 SLC30A3 KCND3 NFIB LPA

1.07e-031206407EFO_0004458
Diseasefree cholesterol to total lipids in large VLDL percentage

LPA PCSK9

1.16e-0337402EFO_0022281
Diseasetriglycerides to total lipids in large VLDL percentage

LPA PCSK9

1.29e-0339402EFO_0022332
Diseaseaspirin use measurement

LPA PCSK9

1.29e-0339402EFO_0007013
DiseaseHypercholesterolemia

LPA PCSK9

1.29e-0339402C0020443

Protein segments in the cluster

PeptideGeneStartEntry
SMTSAHGSASVNSRW

CEP170

1216

Q5SW79
ASSPSRSRHSPYAWM

CDX4

146

O14627
STPHNVSWRDSTMGS

CASP4

306

P49662
EAYWRATHTTSSTPM

CACNB4

396

O00305
SHSWEMPSSDTNANT

AKAP8L

66

Q9ULX6
RTWHERDQDMSSPTT

NFIB

301

O00712
RAPSWQTGMHSSAAT

QSER1

26

Q2KHR3
RFISHSSSSSWGMAR

KAT6B

596

Q8WYB5
GMWRPLSSSSAQTNH

ARHGEF17

666

Q96PE2
MDTWPTRSAQFSSSH

MUC16

901

Q8WXI7
RRSSTWSMTAHATTY

DCC

926

P43146
RQTMWRAFENPHTST

KCND3

166

Q9UK17
MESSPFNRRQWTSLS

LIMA1

1

Q9UHB6
NSTRMSPSSSAWAKL

ITPRID1

1011

Q6ZRS4
ASSRTSTGNVWMTHE

PPFIA3

911

O75145
AGSRRSSISSWLSEM

KIF26B

1271

Q2KJY2
WSAHSGPTRMATAVA

PCSK9

461

Q8NBP7
DTPASWMHARHGSSR

PLXNA1

846

Q9UIW2
DMWTTFRPRSSSNAS

FOXO4

251

P98177
TRHTASAWLMSAPNS

PGLYRP2

46

Q96PD5
RQWNFVATMSTPRST

KLHL5

586

Q96PQ7
VAREHNSMWASLSSP

INF2

576

Q27J81
MWTVKTSSSGRHSVR

HMCN1

296

Q96RW7
RTCMSESTWNPEHRS

DENND4C

1111

Q5VZ89
AWSSMTPHQHNRTTE

LPA

51

P08519
SWSSMTPHWHQRTTE

LPA

1191

P08519
MNRTSGAPSSWHSSS

HASPIN

426

Q8TF76
DSSWRHSQVPRSSSM

MARCHF7

116

Q9H992
DGRPAWMRTLHTTAS

DYNC1H1

4371

Q14204
SSGPSETNHWRRMLN

SYT17

431

Q9BSW7
RRSSTWSMTAHGTTF

NEO1

936

Q92859
LRRSMDQGSTWSPTA

NEU1

111

Q99519
NVSRSPWFTHITSSM

ABCC12

981

Q96J65
RMWSEPFHSKSSSSR

SPPL3

366

Q8TCT6
THPSQFLRSSTQMTW

XPO5

361

Q9HAV4
MPSVSRSTSRSSANW

TRPV6

721

Q9H1D0
STRPATRTMTFGWHR

SLC30A3

126

Q99726
WESSLPASRMHRTLS

TMEM221

246

A6NGB7
DHNTRTTTWQRPTME

WWP1

401

Q9H0M0
DDMPHSTSRWRDTAN

PJA1

281

Q8NG27
PSSNTGAWRVSTMNH

TNRC6A

476

Q8NDV7
NRTTQWHRPSLMDVS

NEDD4L

216

Q96PU5