Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZBTB20 SALL3 ZNF628 MYT1 ZKSCAN8 RFX3 RXRB ZNF835 ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 SP9 ELK3 ZNF396 ZNF324B ZNF646	6.18e-05	1244	103	18	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZBTB20 SALL3 ZNF628 MYT1 ZKSCAN8 RFX3 RXRB ZNF835 ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 SP9 ELK3 ZNF396 ZNF324B ZNF646	8.14e-05	1271	103	18	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZBTB20 SALL3 ZNF266 ZNF628 MYT1 ZKSCAN8 RFX3 RXRB ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 ZBTB40 SP9 ELK3 ZNF396 ZNF324B ZNF646	9.90e-05	1412	103	19	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZBTB20 SALL3 ZNF266 ZNF628 MYT1 ZKSCAN8 RFX3 RXRB ZNF835 ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 SP9 ELK3 ZNF396 ZNF324B ZNF646	1.52e-04	1459	103	19	GO:0000977
GeneOntologyMolecularFunction	disaccharide binding	LGALS9C LGALS9B	5.44e-04	7	103	2	GO:0048030
GeneOntologyMolecularFunction	galactoside binding	LGALS9C LGALS9B	9.26e-04	9	103	2	GO:0016936
GeneOntologyCellularComponent	IRE1-TRAF2-ASK1 complex	ERN1 MAP3K5	1.41e-04	4	102	2	GO:1990604
GeneOntologyCellularComponent	elongator holoenzyme complex	ELP6 ELP3	3.49e-04	6	102	2	GO:0033588
GeneOntologyCellularComponent	extracellular matrix	LGALS9C FLG LGALS9B LAMB2 THBS3 HMCN2 LRIG1 PRELP MMRN2 SERPINF2 RTN4RL2	3.58e-04	656	102	11	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	LGALS9C FLG LGALS9B LAMB2 THBS3 HMCN2 LRIG1 PRELP MMRN2 SERPINF2 RTN4RL2	3.67e-04	658	102	11	GO:0030312
Domain	-	ZBTB20 SALL3 ZNF266 ZNF628 ZKSCAN8 ZNF214 ZNF835 ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 ZBTB40 SP9 ZNF396 ZNF324B ZNF646	1.72e-07	679	103	17	3.30.160.60
Domain	zf-C2H2	ZBTB20 SALL3 ZNF266 ZNF628 ZKSCAN8 ZNF214 ZNF835 ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 ZBTB40 SP9 ZNF396 ZNF324B ZNF646	2.30e-07	693	103	17	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZBTB20 SALL3 ZNF266 ZNF628 ZKSCAN8 ZNF214 ZNF835 ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 ZBTB40 SP9 ZNF396 ZNF324B ZNF646	2.35e-07	694	103	17	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZBTB20 SALL3 ZNF266 ZNF628 ZKSCAN8 ZNF214 ZNF835 ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 ZBTB40 SP9 ZNF396 ZNF324B ZNF646	1.09e-06	775	103	17	PS50157
Domain	ZINC_FINGER_C2H2_1	ZBTB20 SALL3 ZNF266 ZNF628 ZKSCAN8 ZNF214 ZNF835 ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 ZBTB40 SP9 ZNF396 ZNF324B ZNF646	1.13e-06	777	103	17	PS00028
Domain	Znf_C2H2-like	ZBTB20 SALL3 ZNF266 ZNF628 ZKSCAN8 ZNF214 ZNF835 ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 ZBTB40 SP9 ZNF396 ZNF324B ZNF646	1.57e-06	796	103	17	IPR015880
Domain	Znf_C2H2	ZBTB20 SALL3 ZNF266 ZNF628 ZKSCAN8 ZNF214 ZNF835 ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 ZBTB40 SP9 ZNF396 ZNF324B ZNF646	1.83e-06	805	103	17	IPR007087
Domain	ZnF_C2H2	ZBTB20 SALL3 ZNF266 ZNF628 ZKSCAN8 ZNF214 ZNF835 ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 ZBTB40 SP9 ZNF396 ZNF324B ZNF646	1.92e-06	808	103	17	SM00355
Domain	zf-C2H2_6	ZNF266 ZKSCAN8 ZNF526 ZNF24 ZNF792 ZNF358 ZNF324B ZNF646	3.48e-04	314	103	8	PF13912
Domain	EGF_CA	THBS3 FAT1 HMCN2 LRP4	1.31e-03	86	103	4	PF07645
Domain	Cys-rich_flank_reg_C	LGI4 AMIGO1 LRIG1 RTN4RL2	1.55e-03	90	103	4	IPR000483
Domain	LRRCT	LGI4 AMIGO1 LRIG1 RTN4RL2	1.55e-03	90	103	4	SM00082
Domain	Growth_fac_rcpt_	LAMB2 THBS3 FAT1 HMCN2 LRP4	1.73e-03	156	103	5	IPR009030
Domain	-	LGALS9C LGALS9B THBS3 FAT1	1.89e-03	95	103	4	2.60.120.200
Domain	EGF_Ca-bd_CS	THBS3 FAT1 HMCN2 LRP4	2.04e-03	97	103	4	IPR018097
Domain	LRRNT	AMIGO1 LRIG1 PRELP RTN4RL2	2.12e-03	98	103	4	IPR000372
Domain	LRRNT	AMIGO1 LRIG1 PRELP RTN4RL2	2.12e-03	98	103	4	SM00013
Domain	EGF_CA	THBS3 FAT1 HMCN2 LRP4	2.20e-03	99	103	4	PS01187
Domain	-	ASB6 CASKIN1 ANKDD1B ANKRD18A TNKS GPANK1	2.52e-03	248	103	6	1.25.40.20
Domain	LRR_8	LGI4 AMIGO1 LRIG1 PRELP RTN4RL2	2.58e-03	171	103	5	PF13855
Domain	ANK	ASB6 CASKIN1 ANKDD1B ANKRD18A TNKS GPANK1	2.68e-03	251	103	6	SM00248
Domain	ANK_REPEAT	ASB6 CASKIN1 ANKDD1B ANKRD18A TNKS GPANK1	2.79e-03	253	103	6	PS50088
Domain	Ankyrin_rpt-contain_dom	ASB6 CASKIN1 ANKDD1B ANKRD18A TNKS GPANK1	2.84e-03	254	103	6	IPR020683
Domain	ANK_REP_REGION	ASB6 CASKIN1 ANKDD1B ANKRD18A TNKS GPANK1	2.84e-03	254	103	6	PS50297
Domain	Leu-rich_rpt_typical-subtyp	LGI4 AMIGO1 LRIG1 PRELP RTN4RL2	2.99e-03	177	103	5	IPR003591
Domain	LRR_TYP	LGI4 AMIGO1 LRIG1 PRELP RTN4RL2	2.99e-03	177	103	5	SM00369
Domain	Gal-bind_lectin	LGALS9C LGALS9B	3.02e-03	15	103	2	PF00337
Domain	Gal-bind_lectin	LGALS9C LGALS9B	3.02e-03	15	103	2	SM00908
Domain	GALECTIN	LGALS9C LGALS9B	3.02e-03	15	103	2	PS51304
Domain	Galectin_CRD	LGALS9C LGALS9B	3.02e-03	15	103	2	IPR001079
Domain	GLECT	LGALS9C LGALS9B	3.02e-03	15	103	2	SM00276
Domain	Ankyrin_rpt	ASB6 CASKIN1 ANKDD1B ANKRD18A TNKS GPANK1	3.31e-03	262	103	6	IPR002110
Domain	SCAN	ZKSCAN8 ZNF24 ZNF396	3.65e-03	56	103	3	SM00431
Domain	Leu-rich_rpt	TCTE1 LGI4 AMIGO1 LRIG1 PRELP RTN4RL2	3.90e-03	271	103	6	IPR001611
Domain	SCAN_BOX	ZKSCAN8 ZNF24 ZNF396	4.03e-03	58	103	3	PS50804
Domain	SCAN	ZKSCAN8 ZNF24 ZNF396	4.03e-03	58	103	3	PF02023
Domain	SCAN_dom	ZKSCAN8 ZNF24 ZNF396	4.03e-03	58	103	3	IPR003309
Domain	Ig_I-set	AMIGO1 IGDCC4 HMCN2 LRIG1 SDK1	4.05e-03	190	103	5	IPR013098
Domain	I-set	AMIGO1 IGDCC4 HMCN2 LRIG1 SDK1	4.05e-03	190	103	5	PF07679
Domain	Retrov_capsid_C	ZKSCAN8 ZNF24 ZNF396	4.23e-03	59	103	3	IPR008916
Domain	Terpenoid_cyclase/PrenylTrfase	ASIC3 C3	4.35e-03	18	103	2	IPR008930
Domain	EGF_CA	THBS3 FAT1 HMCN2 LRP4	4.66e-03	122	103	4	SM00179
Domain	EGF-like_Ca-bd_dom	THBS3 FAT1 HMCN2 LRP4	4.93e-03	124	103	4	IPR001881
Domain	zf-MYND	SMYD4 ZMYND12	5.91e-03	21	103	2	PF01753
Domain	Znf_MYND	SMYD4 ZMYND12	6.47e-03	22	103	2	IPR002893
Domain	ZF_MYND_1	SMYD4 ZMYND12	6.47e-03	22	103	2	PS01360
Domain	ZF_MYND_2	SMYD4 ZMYND12	6.47e-03	22	103	2	PS50865
Domain	Ank_2	ASB6 CASKIN1 ANKDD1B ANKRD18A TNKS	6.79e-03	215	103	5	PF12796
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ZNF628 GTSE1 FBRSL1 LAMB2 CUL9 ELP6 SPATA20 MAP3K5 CDR2L FAT1 ZFP36L2 CASKIN1 STRN4 LRP4 ZFYVE26 ZNF324B	2.14e-07	1105	105	16	35748872
Pubmed	Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.	ZBTB20 SALL3 RFX3 ZNF24 VARS1	5.83e-07	53	105	5	21532573
Pubmed	Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice.	ZBTB20 C3	9.03e-06	2	105	2	18562603
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	VPS11 STRBP ELP6 ELP3 FBXO30 NAA35 AKAP11	1.17e-05	251	105	7	29778605
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	STRBP MAP3K5 DMXL1 NAA35 GPR158 CASKIN1 C3 TNKS DDX20	1.45e-05	475	105	9	31040226
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	LGALS9C LGALS9B LAMB2 HMCN2 PRELP SERPINF2	1.59e-05	175	105	6	28071719
Pubmed	Galectin-9 Is Critical for Mucosal Adaptive Immunity through the T Helper 17-IgA Axis.	LGALS9C LGALS9B	2.70e-05	3	105	2	29458010
Pubmed	Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation.	LGALS9C LGALS9B	2.70e-05	3	105	2	19776007
Pubmed	Cooperative Interactions of Oligosaccharide and Peptide Moieties of a Glycopeptide Derived from IgE with Galectin-9.	LGALS9C LGALS9B	2.70e-05	3	105	2	26582205
Pubmed	Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.	LGALS9C LGALS9B	2.70e-05	3	105	2	9153289
Pubmed	Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis.	LGALS9C LGALS9B	2.70e-05	3	105	2	33316546
Pubmed	Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice.	LGALS9C LGALS9B	2.70e-05	3	105	2	18974023
Pubmed	Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.	LGALS9C LGALS9B	2.70e-05	3	105	2	9038233
Pubmed	Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion.	LGALS9C LGALS9B	2.70e-05	3	105	2	23144904
Pubmed	Impaired Gal-9 Dysregulates the PBMC-Induced Th1/Th2 Imbalance in Abortion-Prone Matings.	LGALS9C LGALS9B	2.70e-05	3	105	2	29651447
Pubmed	Protective effect of Galectin-9 in murine model of lung emphysema: Involvement of neutrophil migration and MMP-9 production.	LGALS9C LGALS9B	2.70e-05	3	105	2	28704475
Pubmed	The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity.	LGALS9C LGALS9B	2.70e-05	3	105	2	21146220
Pubmed	Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.	LGALS9C LGALS9B	2.70e-05	3	105	2	23836896
Pubmed	Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes.	LGALS9C LGALS9B	2.70e-05	3	105	2	7890611
Pubmed	Psoralen Inhibited Apoptosis of Osteoporotic Osteoblasts by Modulating IRE1-ASK1-JNK Pathway.	ERN1 MAP3K5	2.70e-05	3	105	2	28349059
Pubmed	Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner.	LGALS9C LGALS9B	2.70e-05	3	105	2	22341088
Pubmed	Regulation of M1‑type and M2‑type macrophage polarization in RAW264.7 cells by Galectin‑9.	LGALS9C LGALS9B	2.70e-05	3	105	2	28990062
Pubmed	Galectin-9 Is a Novel Regulator of Epithelial Restitution.	LGALS9C LGALS9B	2.70e-05	3	105	2	32380082
Pubmed	Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts.	LGALS9C LGALS9B	2.70e-05	3	105	2	23667648
Pubmed	Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices.	LGALS9C LGALS9B	2.70e-05	3	105	2	18579572
Pubmed	Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.	LGALS9C LGALS9B	2.70e-05	3	105	2	28877989
Pubmed	Galectin-9 ameliorates immune complex-induced arthritis by regulating Fc gamma R expression on macrophages.	LGALS9C LGALS9B	2.70e-05	3	105	2	19800850
Pubmed	The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy.	LGALS9C LGALS9B	2.70e-05	3	105	2	38987795
Pubmed	Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition.	LGALS9C LGALS9B	2.70e-05	3	105	2	16990264
Pubmed	Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue.	LGALS9C LGALS9B	2.70e-05	3	105	2	18005988
Pubmed	Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducing plasma cell apoptosis independently of Tim-3.	LGALS9C LGALS9B	2.70e-05	3	105	2	23585851
Pubmed	Galectin-9 ameliorates anti-GBM glomerulonephritis by inhibiting Th1 and Th17 immune responses in mice.	LGALS9C LGALS9B	2.70e-05	3	105	2	24477688
Pubmed	A unique role for galectin-9 in angiogenesis and inflammatory arthritis.	LGALS9C LGALS9B	2.70e-05	3	105	2	29433546
Pubmed	Oncogenic miR-93-5p/Gal-9 axis drives CD8 (+) T-cell inactivation and is a therapeutic target for hepatocellular carcinoma immunotherapy.	LGALS9C LGALS9B	2.70e-05	3	105	2	37105392
Pubmed	Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models.	ZBTB20 C3	2.70e-05	3	105	2	23747948
Pubmed	Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.	LGALS9C LGALS9B	2.70e-05	3	105	2	36479526
Pubmed	Clinical investigation of lipopolysaccharide in the persistence of metabolic syndrome (MS) through the activation of GRP78-IRE1α-ASK1 signaling pathway.	ERN1 MAP3K5	2.70e-05	3	105	2	34850317
Pubmed	Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy.	LGALS9C LGALS9B	2.70e-05	3	105	2	23242525
Pubmed	Galectin-9 in allergic airway inflammation and hyper-responsiveness in mice.	LGALS9C LGALS9B	2.70e-05	3	105	2	19851072
Pubmed	The Role of Galectin-9 as Mediator of Atopic Dermatitis: Effect on Keratinocytes.	LGALS9C LGALS9B	2.70e-05	3	105	2	33923930
Pubmed	Alarmin function of galectin-9 in murine respiratory tularemia.	LGALS9C LGALS9B	2.70e-05	3	105	2	25898318
Pubmed	IRE1α-TRAF2-ASK1 complex-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to CXC195-induced apoptosis in human bladder carcinoma T24 cells.	ERN1 MAP3K5	2.70e-05	3	105	2	25797626
Pubmed	Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells.	LGALS9C LGALS9B	2.70e-05	3	105	2	31937306
Pubmed	Intestinal epithelial cells express galectin-9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine.	LGALS9C LGALS9B	2.70e-05	3	105	2	21426359
Pubmed	Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.	LGALS9C LGALS9B	2.70e-05	3	105	2	31969388
Pubmed	Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis.	LGALS9C LGALS9B	2.70e-05	3	105	2	18282810
Pubmed	Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.	LGALS9C LGALS9B	2.70e-05	3	105	2	35241678
Pubmed	Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.	LGALS9C LGALS9B	2.70e-05	3	105	2	24083426
Pubmed	Galectin-9 in synergy with NF-κB inhibition restores immune regulatory capability in dendritic cells of subjects with food allergy.	LGALS9C LGALS9B	2.70e-05	3	105	2	37279535
Pubmed	The protective function of galectin-9 in liver ischemia and reperfusion injury in mice.	LGALS9C LGALS9B	2.70e-05	3	105	2	25931247
Pubmed	Possible regulatory role of galectin-9 on Ascaris suum-induced eosinophilic lung inflammation in mice.	LGALS9C LGALS9B	2.70e-05	3	105	2	22627368
Pubmed	Galectin-9 is required for endometrial regenerative cells to induce long-term cardiac allograft survival in mice.	LGALS9C LGALS9B	2.70e-05	3	105	2	33153471
Pubmed	T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses.	LGALS9C LGALS9B	2.70e-05	3	105	2	22052881
Pubmed	Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes.	LGALS9C LGALS9B	2.70e-05	3	105	2	17560833
Pubmed	Galectin-9 supports primary T cell transendothelial migration in a glycan and integrin dependent manner.	LGALS9C LGALS9B	2.70e-05	3	105	2	35643073
Pubmed	Galectin-9 functionally impairs natural killer cells in humans and mice.	LGALS9C LGALS9B	2.70e-05	3	105	2	23408620
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	ZBTB20 ERN1 ENPP2 ZKSCAN8 RNF213 RXRB FAT1 ZBTB40 AKAP11	4.67e-05	552	105	9	10737800
Pubmed	SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.	LGALS9C LGALS9B	5.40e-05	4	105	2	38686388
Pubmed	Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells.	LGALS9C LGALS9B	5.40e-05	4	105	2	22677125
Pubmed	Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.	LGALS9C LGALS9B	5.40e-05	4	105	2	19234217
Pubmed	CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum.	ERN1 ERO1A	5.40e-05	4	105	2	15601821
Pubmed	Tim-3/Galectin-9 signaling pathway is involved in the cytokine changes in mice with alveolar echinococcosis.	LGALS9C LGALS9B	5.40e-05	4	105	2	35715604
Pubmed	ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats.	ERN1 MAP3K5	5.40e-05	4	105	2	12050113
Pubmed	Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.	LGALS9C LGALS9B	5.40e-05	4	105	2	19017954
Pubmed	Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.	LGALS9C LGALS9B	5.40e-05	4	105	2	33963043
Pubmed	Galectin-9: A novel promoter of atherosclerosis progression.	LGALS9C LGALS9B	5.40e-05	4	105	2	36459823
Pubmed	Newly characterized decidual Tim-3+ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts.	LGALS9C LGALS9B	5.40e-05	4	105	2	33107565
Pubmed	Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.	LGALS9C LGALS9B	5.40e-05	4	105	2	29611821
Pubmed	Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway.	LGALS9C LGALS9B	5.40e-05	4	105	2	30763585
Pubmed	Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2.	LGALS9C LGALS9B	5.40e-05	4	105	2	33727589
Pubmed	Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells.	LGALS9C LGALS9B	5.40e-05	4	105	2	19362679
Pubmed	The Galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal-fetal interface in early pregnancy.	LGALS9C LGALS9B	5.40e-05	4	105	2	25578313
Pubmed	Intestinal Lamina Propria CD4+ T Cells Promote Bactericidal Activity of Macrophages via Galectin-9 and Tim-3 Interaction during Salmonella enterica Serovar Typhimurium Infection.	LGALS9C LGALS9B	5.40e-05	4	105	2	29844236
Pubmed	Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response.	LGALS9C LGALS9B	5.40e-05	4	105	2	20463811
Pubmed	Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas.	LGALS9C LGALS9B	5.40e-05	4	105	2	32855403
Pubmed	Galectin-3 mediates oligomerization of secreted hensin using its carbohydrate-recognition domain.	LGALS9C LGALS9B	5.40e-05	4	105	2	23657851
Pubmed	[Expression and significance of galectin-3 and galectin-9 in mice nasal mucosa with allergic rhinitis].	LGALS9C LGALS9B	5.40e-05	4	105	2	18826117
Pubmed	Ursolic acid induces ER stress response to activate ASK1-JNK signaling and induce apoptosis in human bladder cancer T24 cells.	ERN1 MAP3K5	5.40e-05	4	105	2	23000344
Pubmed	The Tim-3/galectin-9 pathway involves in the homeostasis of hepatic Tregs in a mouse model of concanavalin A-induced hepatitis.	LGALS9C LGALS9B	5.40e-05	4	105	2	24333756
Pubmed	The expression of Galectin-9 correlates with mTOR and AMPK in murine colony-forming erythroid progenitors.	LGALS9C LGALS9B	5.40e-05	4	105	2	38853593
Pubmed	Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.	LGALS9C LGALS9B	5.40e-05	4	105	2	24958847
Pubmed	Galectin-9 binds IgM-BCR to regulate B cell signaling.	LGALS9C LGALS9B	5.40e-05	4	105	2	30120235
Pubmed	[Expression of Galectin-9 and Tim-3 in lungs of mice with asthma].	LGALS9C LGALS9B	5.40e-05	4	105	2	21575348
Pubmed	Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts.	LGALS9C LGALS9B	5.40e-05	4	105	2	18346632
Pubmed	Isolation and characterization of a novel eosinophil-specific galectin released into the lungs in response to allergen challenge.	LGALS9C LGALS9B	5.40e-05	4	105	2	11839756
Pubmed	Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice.	LGALS9C LGALS9B	5.40e-05	4	105	2	19670381
Pubmed	Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury.	LGALS9C LGALS9B	5.40e-05	4	105	2	25450716
Pubmed	The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.	LGALS9C LGALS9B	5.40e-05	4	105	2	16286920
Pubmed	Identification and characterization of two novel human SCAN domain-containing zinc finger genes ZNF396 and ZNF397.	ZNF24 ZNF396	5.40e-05	4	105	2	12801647
Pubmed	Galectin-9 regulates the threshold of B cell activation and autoimmunity.	LGALS9C LGALS9B	5.40e-05	4	105	2	34369876
Pubmed	Targeting the CD146/Galectin-9 axis protects the integrity of the blood-brain barrier in experimental cerebral malaria.	LGALS9C LGALS9B	5.40e-05	4	105	2	33203936
Pubmed	Influence of galectin-9/Tim-3 interaction on herpes simplex virus-1 latency.	LGALS9C LGALS9B	5.40e-05	4	105	2	22021615
Pubmed	Tagging genes with cassette-exchange sites.	LEMD3 STRBP GTSE1 ELP3 DMXL1 TAF4 RSBN1L	7.33e-05	335	105	7	15741177
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	LEMD3 ERO1A RNF213 ZNF792 ASB6 RAB3GAP2 DDX20 CDT1 VARS1 RSBN1L	7.76e-05	733	105	10	34672954
Pubmed	MDM1 is a microtubule-binding protein that negatively regulates centriole duplication.	CEP164 CEP250	8.97e-05	5	105	2	26337392
Pubmed	Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.	LGALS9C LGALS9B	8.97e-05	5	105	2	29242193
Pubmed	Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy loss.	LGALS9C LGALS9B	8.97e-05	5	105	2	28951537
Pubmed	Galectin-9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin-dependent manner.	LGALS9C LGALS9B	8.97e-05	5	105	2	34847625
Pubmed	Complement and microglia mediate early synapse loss in Alzheimer mouse models.	ZBTB20 C3	8.97e-05	5	105	2	27033548
Pubmed	Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice.	LGALS9C LGALS9B	8.97e-05	5	105	2	22469568
Interaction	LTBP2 interactions	ZNF628 ZNF594 ZNF526 ZNF358 ZNF324B ZNF646	4.59e-06	85	102	6	int:LTBP2
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZBTB20 SALL3 ZNF266 ZNF628 ZKSCAN8 ZNF214 ZNF835 ZNF594 ZNF526 ZNF24 ZNF792 ZNF358 ZBTB40 SP9 ZNF396 ZNF324B ZNF646	8.18e-09	718	78	17	28
GeneFamily	Ankyrin repeat domain containing	ANKRD18B ASB6 CASKIN1 ANKDD1B ANKRD18A TNKS GPANK1	8.31e-05	242	78	7	403
GeneFamily	Elongator acetyltransferase complex	ELP6 ELP3	2.73e-04	6	78	2	539
GeneFamily	Galectins	LGALS9C LGALS9B	1.86e-03	15	78	2	629
GeneFamily	Zinc fingers MYND-type	SMYD4 ZMYND12	3.66e-03	21	78	2	87
Coexpression	ZHENG_FOXP3_TARGETS_IN_THYMUS_UP	TPP2 ZBTB20 RFX3 MAP3K5 LRIG1 ZFP36L2 ELK3	1.59e-05	199	105	7	M1746
Coexpression	GSE411_UNSTIM_VS_400MIN_IL6_STIM_MACROPHAGE_UP	FBXW10 ERN1 ZKSCAN8 AMIGO1 MAP3K5 ELK3 SLC12A7	1.64e-05	200	105	7	M5999
Coexpression	ZHENG_FOXP3_TARGETS_IN_THYMUS_UP	TPP2 ZBTB20 RFX3 MAP3K5 LRIG1 ZFP36L2 ELK3	1.64e-05	200	105	7	MM1033
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ZBTB20 ZNF835 PRELP CASKIN1 LRP4 C3 ZMYND12	5.19e-07	200	106	7	4c3c11dd5e71ebc3d62264eeaeb71a850b149779
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDR2L ZNF526 CASKIN1 MMRN2 CDT1 TUBE1	3.21e-06	169	106	6	f086b50791e1c93e253eb5e8d6c4bf617b1416c3
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon\|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.	ZBTB20 LAMB2 MAP3K5 LRIG1 ZFP36L2 SP9	7.74e-06	197	106	6	58b957efd006f43c2fe55071d5c6d06c2e367e72
ToppCell	Sigmoid-T_cell-cycling_gd_T\|T_cell / Region, Cell class and subclass	GTSE1 SPATA20 ZNF594 ZFYVE26 CDT1 FAM124B	8.44e-06	200	106	6	4e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ASIC3 HMCN2 ANKDD1B BAIAP2L2	1.66e-05	64	106	4	bf923a66b17e717b8d3817b9d0e201b82a7e4a88
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ASIC3 HMCN2 ANKDD1B BAIAP2L2	1.66e-05	64	106	4	a3e852600c53b11175eb579e92962fa711f5678b
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ASIC3 HMCN2 ANKDD1B BAIAP2L2	1.66e-05	64	106	4	f8f43ad9354c786b418bac54614f96f50e8bea68
ToppCell	Dividing_Macrophages-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	GTSE1 XRCC3 ASIC3 KIR3DX1 CDT1	3.17e-05	152	106	5	e39cfc346b35235546b303e7d73e4d9d7120a5fb
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B2\|367C / Donor, Lineage, Cell class and subclass (all cells)	LGALS9C ZNF266 LGALS9B ZNF594 KIR3DX1	4.30e-05	162	106	5	59c0dcb5b51c1803660aeec51b60deceeeaeea66
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SALL3 LAMB2 LRIG1 ZFP36L2 LRP4	5.71e-05	172	106	5	55fba5ce0ead1114e1a76f67ad68432c6bac90e5
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBRSL1 SMYD4 PRELP GATD1 SLC12A7	6.20e-05	175	106	5	1d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBRSL1 SMYD4 PRELP GATD1 SLC12A7	6.20e-05	175	106	5	427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBRSL1 XRCC3 MAP3K5 CDT1 OCSTAMP	6.37e-05	176	106	5	450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ENPP2 TM6SF1 C17orf113 MMRN2 GATD1	6.37e-05	176	106	5	1df7b6ce2519ad99bacbbaf1a8d5929e11513faa
ToppCell	PBMC-Mild-cDC_11\|Mild / Compartment, Disease Groups and Clusters	STRBP ENPP2 ANKDD1B SERPINF2 SDK1	6.55e-05	177	106	5	974305e4c0eff90134c4e58cf11b955d1eee0501
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	GTSE1 ZNF214 MMRN2 ANKRD18A CDT1	6.55e-05	177	106	5	26c25d10aa511b64cc7db43a8deea7b5d31bca96
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	TM6SF1 ST6GALNAC5 MMRN2 FAM124B SDK1	6.90e-05	179	106	5	cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ENPP2 LAMB2 IGDCC4 FAT1 MMRN2	6.90e-05	179	106	5	98c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PIGB LAMB2 ZNF526 LRIG1 MMRN2	7.27e-05	181	106	5	136b0c60680068838d184d32aa99d7bea8718dbc
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	GTSE1 CUL9 LRIG1 CHTF18 CDT1	7.66e-05	183	106	5	a716b446c2bf5aa294b8f580aa845098fae76354
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	STRBP MYT1 ZNF24 CASKIN1 ZNF396	8.48e-05	187	106	5	a716b64ca03d9b61da765bf87f065ac9393303f1
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	IGDCC4 HMCN2 ZFP36L2 MMRN2 ELK3	8.70e-05	188	106	5	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZBTB20 ENPP2 ZFP36L2 LRP4 C3	8.92e-05	189	106	5	42ab4cc5fbf8580841f31889446fe4499df1a464
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SALL3 LGI4 IGDCC4 PRELP ST6GALNAC5	9.37e-05	191	106	5	fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZBTB20 ENPP2 ZFP36L2 LRP4 C3	9.37e-05	191	106	5	a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCell	facs-Trachea-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZBTB20 LAMB2 THBS3 PRELP C3	9.60e-05	192	106	5	e8af6ad1ae99cae13a82d0d8d7f38af9b777f0ba
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SALL3 LAMB2 LRIG1 ZFP36L2 LRP4	9.84e-05	193	106	5	b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SALL3 LAMB2 LRIG1 ZFP36L2 LRP4	9.84e-05	193	106	5	40edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZBTB20 LAMB2 THBS3 PRELP C3	1.01e-04	194	106	5	889c6e231bdd5b59902c7d2afdc077360b1d3256
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP2 FAT1 PRELP LRP4 C3	1.06e-04	196	106	5	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP2 FAT1 PRELP LRP4 C3	1.06e-04	196	106	5	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG\|World / Primary Cells by Cluster	SALL3 LAMB2 MAP3K5 LRIG1 LRP4	1.08e-04	197	106	5	61749ccafeb938c310cff1de5ff924a1c794325a
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG-25\|World / Primary Cells by Cluster	SALL3 LAMB2 MAP3K5 LRIG1 LRP4	1.08e-04	197	106	5	9d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	LAMB2 THBS3 FAT1 HMCN2 PRELP	1.11e-04	198	106	5	4f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-IN_Progenitors\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	SALL3 LAMB2 FAT1 LRIG1 ZFP36L2	1.11e-04	198	106	5	3811d9e3e54bbe8b208c591697e43b55ab5bbf0e
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAMB2 NGRN THBS3 LRIG1 ASB6	1.11e-04	198	106	5	399760b6b6fef8639ded53b14f251b9fce600e81
ToppCell	Sigmoid-(1)_T_cell-(14)_Tcm\|Sigmoid / shred on region, Cell_type, and subtype	LGALS9C LGALS9B ANKRD18A CDT1 BAIAP2L2	1.14e-04	199	106	5	ec454fa22fb7f50a947bdf4c4bb6f0ba13f62b4c
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	GTSE1 XRCC3 SP9 CDT1 ZNF324B	1.14e-04	199	106	5	c6d59ed26eadd3c41acfe1b4d929270e00ea3e95
ToppCell	Sigmoid-T_cell-Tcm\|Sigmoid / Region, Cell class and subclass	LGALS9C LGALS9B ANKRD18A CDT1 BAIAP2L2	1.14e-04	199	106	5	f7c729eaa3c8fd5a05cb6f79cac9b8f199c8092b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Macroglial-Astrocyte\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	LAMB2 FAT1 LRIG1 ZFP36L2 LRP4	1.16e-04	200	106	5	29f82e2ad2f1888b6b236a4392b88a84351b8ddc
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Macroglial-Astrocyte\|10w / Sample Type, Dataset, Time_group, and Cell type.	ENPP2 RFX3 FAT1 ZFP36L2 LRP4	1.16e-04	200	106	5	75f5ea38fbd341b80a8058077a04447f0e0eea28
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF835 PRELP CASKIN1 C3 ZMYND12	1.16e-04	200	106	5	36de49593cf6ff1c9229fcceb150c1d68658a360
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Macroglial\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	LAMB2 FAT1 LRIG1 ZFP36L2 LRP4	1.16e-04	200	106	5	46f99bed98da09e6d3f45d4443cbaa6b6c1589bb
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Macroglial\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	LAMB2 FAT1 LRIG1 ZFP36L2 LRP4	1.16e-04	200	106	5	1598a9e8efa72fda7d12df07e7716b326cdf1d5e
ToppCell	Sigmoid-(1)_T_cell-(18)_cycling_gd_T\|Sigmoid / shred on region, Cell_type, and subtype	GTSE1 ZNF594 ZFYVE26 CDT1 FAM124B	1.16e-04	200	106	5	6e367abd1a4b87e20eb9095b8337723163e8bbae
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial-Astrocyte\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	SALL3 FAT1 ZFP36L2 CASKIN1 LRP4	1.16e-04	200	106	5	4fe3b2d80c567c18621bff3341f9a73578c81621
ToppCell	Sigmoid-T_cell-cycling_gd_T\|Sigmoid / Region, Cell class and subclass	GTSE1 ZNF594 ZFYVE26 CDT1 FAM124B	1.16e-04	200	106	5	9769185abae084ffac36420c749625e679b70ca8
Drug	beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; MCF7; HT_HG-U133A	ERN1 CUL9 CEP164 THBS3 ZFP36L2 CEP250 MMRN2 LRP4	3.71e-06	197	105	8	2819_UP
Drug	fullerene C60	FLG VPS11 ZBTB20 LEMD3 GTSE1 SPATA20 RFX3 RXRB CEP164 AMIGO1 NAA35 ZFP36L2 ASB6 RAB3GAP2 STRN4 SP9 CDT1 SERPINF2 SLC12A7 RTN4RL2 VARS1	4.05e-06	1498	105	21	ctd:C069837
Disease	pigment epithelium-derived factor measurement	SMYD4 SERPINF2	3.34e-05	3	99	2	EFO_0021847
Disease	Hodgkins lymphoma	LGI4 ZNF526 SERPINF2 RTN4RL2	1.71e-04	82	99	4	EFO_0000183
Disease	Tinnitus	FBRSL1 TNKS SDK1 BAIAP2L2	9.80e-04	130	99	4	HP_0000360
Disease	COVID-19 (is_implicated_in)	C3 SERPINF2	2.24e-03	21	99	2	DOID:0080600 (is_implicated_in)
Disease	Myasthenic Syndromes, Congenital	LAMB2 LRP4	2.93e-03	24	99	2	C0751882
Disease	Head Neoplasms	XRCC3 FAT1	2.93e-03	24	99	2	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	XRCC3 FAT1	2.93e-03	24	99	2	C0887900
Disease	Cancer of Head	XRCC3 FAT1	2.93e-03	24	99	2	C0751177
Disease	Neck Neoplasms	XRCC3 FAT1	3.18e-03	25	99	2	C0027533
Disease	Cancer of Neck	XRCC3 FAT1	3.18e-03	25	99	2	C0746787

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLAGAAHHSQSFQLL	CHTF18	681	Q8WVB6
STSHLALRSQAQHQL	FBRSL1	361	Q9HCM7
LLLSHNHLNFISSEA	AMIGO1	91	Q86WK6
ASRHAGNLTLHANSV	CDR2L	331	Q86X02
GTSLAERLLSHHANI	ANKRD18A	146	Q8IVF6
GAAHASVILTRDHLN	ACAD8	286	Q9UKU7
ALSHLALGAQNHTLQ	SERPINF2	116	P08697
LLTVSALQHAHNSGE	FBXW10	816	Q5XX13
GTSLAERLLSHHANI	ANKRD18B	146	A2A2Z9
AADLAHITARLAHQT	CDT1	526	Q9H211
RQHARASHLGLARSN	C3	736	P01024
GSVLRTHHTNTLSNI	AKAP11	501	Q9UKA4
LHALASSDGVQIHNT	ASB6	176	Q9NWX5
SHQSHLILRAEGLAT	ELP6	201	Q0PNE2
SASRNHHGSAQEQLR	FLG	2586	P20930
SNLHSRAQHLADILS	DDX20	316	Q9UHI6
RAQLLHQGLSTSHFA	DMXL1	1561	Q9Y485
LLRHVTSGAHRQALA	C17orf113	76	A0A1B0GUU1
HFSQEALLSVAHRGS	IGDCC4	221	Q8TDY8
ADLANLSHLFLHGNR	RTN4RL2	176	Q86UN3
VAASSSLRINHANHT	LEMD3	416	Q9Y2U8
AALLSAHVGHSVAAQ	RAB3GAP2	836	Q9H2M9
DSATGIITLSNLHRH	FAT1	2441	Q14517
SALHHAALNGNTELI	CASKIN1	51	Q8WXD9
AQSLAHALAHNTNLI	TCTE1	351	Q5JU00
GLTALHQLHLSNNSI	LRIG1	281	Q96JA1
LRLSHNSISHIAEGA	LRIG1	336	Q96JA1
LAHSLQHLRGSGNTS	NGRN	146	Q9NPE2
QDSNHRTSTAHLLSL	GPANK1	226	O95872
LTGHHLILSSRQDNT	MTMR9	31	Q96QG7
SLHRALDTLTHATNF	GPR158	121	Q5T848
LNASLHGLHNALFAT	MMRN2	726	Q9H8L6
SHLRHQLQNGSLTIR	HMCN2	4256	Q8NDA2
SAQRFHINLCSGSHI	LGALS9C	251	Q6DKI2
HNQRSVLQLLHSTSD	ARMC9	371	Q7Z3E5
SAQRFHINLCSGSHI	LGALS9B	251	Q3B8N2
ALVSHSEGANHTLLR	BAIAP2L2	331	Q6UXY1
NQRALGKLSAHTHTL	LAMB2	1386	P55268
HSSTNLLQEGLGSHR	ASIC3	481	Q9UHC3
AHLLALHIESSSRNQ	GTSE1	86	Q9NYZ3
TRSHELHTGLSNNIT	KIR3DX1	66	Q9H7L2
LASSGSLARILQHFH	GATD1	101	Q8NB37
TVHLLANSGHGSLLQ	FAM124B	11	Q9H5Z6
HLGGAAALQTLAQHL	HEATR3	481	Q7Z4Q2
QTTSGLAHLHSLNIV	ERN1	671	O75460
GLHHSLSHSLLAVAQ	CEP250	2386	Q9BV73
AHKHGLAALRSTSRN	ELK3	121	P41970
IRNLHDALSGHTSNN	ELP3	186	Q9H9T3
ISGLHASINVHLSAR	ERO1A	251	Q96HE7
QALAAHDAGSRAHVL	CUL9	191	Q8IWT3
HDAGSRAHVLLSLSQ	CUL9	196	Q8IWT3
ARNCVLGLHNDHLSS	FBXO30	601	Q8TB52
QLIHDRNTASHTAAA	SLC12A7	951	Q9Y666
RSHIVRGNHTQSALL	SDK1	1326	Q7Z5N4
SDSALQIHLRSHTGE	SALL3	431	Q9BXA9
GTHGSLNHLLRTNTF	ENPP2	526	Q13822
QCLNSHSHARGSSRA	LILRA3	166	Q8N6C8
SHDSQSAHRSLNVQL	MAP3K5	1231	Q99683
DASLTLHGLQNRSHG	PIGB	16	Q92521
NLSLVDTRQHSSAHS	RSBN1L	821	Q6PCB5
HLGHALTNAIQDSLT	VARS1	351	P26640
QTLNGSAALLNSHHA	TAF4	196	O00268
SLCHANRSAALFHLG	SMYD4	106	Q8IYR2
SRAFLHALLHSDNTA	QTRT1	326	Q9BXR0
RGLRSLTHLSLANNH	LGI4	121	Q8N135
GRDASHSLNQHLQAL	NBPF7P	136	P0C2Y1
GLSTHRSSLLNSHLQ	RFX3	171	P48380
SSGHLLHSRQGSQID	ST6GALNAC5	101	Q9BVH7
ITHSAQHALRLSAFG	STRBP	306	Q96SI9
LNTTHQLHAASRALG	OCSTAMP	161	Q9BR26
NSFNISNLLVLHLSH	PRELP	286	P51888
SNLLVLHLSHNRISS	PRELP	291	P51888
AAAASHLLSTSQHLL	SP9	241	P0CG40
HLLSTSQHLLAQDGF	SP9	246	P0CG40
LLATGLHVHRNSAHS	RXRB	396	P28702
NRTALHFAVGRNHLS	ANKDD1B	101	A6NHY2
IHGLSHSLRQISSQL	CEP164	1261	Q9UPV0
SASEQLRLLQHSHSQ	CEP164	1386	Q9UPV0
HSSDGLRQLLHNRIT	RNF213	4816	Q63HN8
SQGSALILHQRIHSG	ZNF24	261	P17028
QTLHRQSLANADHTT	VPS11	441	Q9H270
RTANSHLSNLVLHGD	USP16	766	Q9Y5T5
LLSAIHNSLHHGIQA	NAA35	271	Q5VZE5
GHSHSLLALANNTCV	TUBE1	391	Q9UJT0
NSVSAHNLLRLHGFT	SPATA20	646	Q8TB22
GQTALHRAALAGHLQ	TNKS	591	O95271
SHRLSNTLSLDIHEN	TPP2	911	P29144
AGSLTNHRQSHTLGI	ZNF646	251	O15015
AGSLLNHRRSHETGQ	ZNF646	1311	O15015
SIHSAVTNALHSILG	THBS3	211	P49746
LLERHVALHSASNGT	ZBTB20	676	Q9HC78
CSNATHSLLHRNLGL	ZMYND12	166	Q9H0C1
NQSSSLNNHRRLHTG	ZNF792	516	Q3KQV3
AFSQGSSLALHQRTH	ZNF835	426	Q9Y2P0
SLANLSRHQLTHTGA	ZNF526	511	Q8TF50
NQSSDLLRHHRIHSG	ZNF594	606	Q96JF6
IRSLAFHHSQSALLT	STRN4	441	Q9NRL3
SQSSALILHQRIHSG	ZNF396	261	Q96N95
GFLRRHSASNLHALA	ZFP36L2	51	P47974
TRLGTLAQLHASHCL	ZFYVE26	1251	Q68DK2
HLRGSSILTALQLHQ	XRCC3	56	O43542
SQSSNLRIHQLVHTG	ZNF214	396	Q9UL59
SQSAGLILHQRIHSG	ZKSCAN8	416	Q15776
AANSTLKNHLRLHTG	ZBTB40	846	Q9NUA8
AQAQFSHIGASLHAR	TM6SF1	306	Q9BZW5
GQSSALLQHQRTHTA	ZNF358	301	Q9NW07
RQLGLSSSHHSLDNA	UNC79	471	Q9P2D8
RSSNLTQHQLLHTGE	ZNF324B	436	Q6AW86
SSNLLLHQRTHGAAP	ZNF628	216	Q5EBL2
AFAISSNLSGHLRIH	ZNF266	416	Q14584
TLHRISRANLDGSQH	LRP4	1101	O75096
HVNSNRNTHRSLSGC	MYT1	496	Q01538