| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | histone H3K4 monomethyltransferase activity | 5.28e-05 | 8 | 28 | 2 | GO:0140945 | |
| GeneOntologyMolecularFunction | histone H3K4 trimethyltransferase activity | 8.47e-05 | 10 | 28 | 2 | GO:0140999 | |
| GeneOntologyMolecularFunction | histone H3K4 methyltransferase activity | 3.55e-04 | 20 | 28 | 2 | GO:0042800 | |
| GeneOntologyMolecularFunction | histone H3 methyltransferase activity | 1.73e-03 | 44 | 28 | 2 | GO:0140938 | |
| GeneOntologyMolecularFunction | S-adenosylmethionine-dependent methyltransferase activity | 1.76e-03 | 172 | 28 | 3 | GO:0008757 | |
| GeneOntologyMolecularFunction | methyltransferase activity | 3.22e-03 | 213 | 28 | 3 | GO:0008168 | |
| GeneOntologyMolecularFunction | transferase activity, transferring one-carbon groups | 3.71e-03 | 224 | 28 | 3 | GO:0016741 | |
| GeneOntologyMolecularFunction | protein-lysine N-methyltransferase activity | 4.08e-03 | 68 | 28 | 2 | GO:0016279 | |
| GeneOntologyMolecularFunction | lysine N-methyltransferase activity | 4.20e-03 | 69 | 28 | 2 | GO:0016278 | |
| GeneOntologyMolecularFunction | histone methyltransferase activity | 4.44e-03 | 71 | 28 | 2 | GO:0042054 | |
| Domain | FYrich_C | 2.16e-05 | 5 | 28 | 2 | IPR003889 | |
| Domain | FYrich_N | 2.16e-05 | 5 | 28 | 2 | IPR003888 | |
| Domain | FYRC | 2.16e-05 | 5 | 28 | 2 | SM00542 | |
| Domain | FYRN | 2.16e-05 | 5 | 28 | 2 | SM00541 | |
| Domain | FYRN | 2.16e-05 | 5 | 28 | 2 | PF05964 | |
| Domain | FYRC | 2.16e-05 | 5 | 28 | 2 | PF05965 | |
| Domain | FYRC | 2.16e-05 | 5 | 28 | 2 | PS51543 | |
| Domain | FYRN | 2.16e-05 | 5 | 28 | 2 | PS51542 | |
| Domain | Post-SET_dom | 2.57e-04 | 16 | 28 | 2 | IPR003616 | |
| Domain | PostSET | 2.57e-04 | 16 | 28 | 2 | SM00508 | |
| Domain | POST_SET | 2.57e-04 | 16 | 28 | 2 | PS50868 | |
| Domain | EPHD | 4.91e-04 | 22 | 28 | 2 | PS51805 | |
| Domain | AT_hook | 7.43e-04 | 27 | 28 | 2 | SM00384 | |
| Domain | AT_hook_DNA-bd_motif | 7.43e-04 | 27 | 28 | 2 | IPR017956 | |
| Domain | PID | 8.00e-04 | 28 | 28 | 2 | PF00640 | |
| Domain | PID | 1.05e-03 | 32 | 28 | 2 | PS01179 | |
| Domain | Znf_FYVE_PHD | 1.35e-03 | 147 | 28 | 3 | IPR011011 | |
| Domain | PTB | 1.63e-03 | 40 | 28 | 2 | SM00462 | |
| Domain | SET | 1.71e-03 | 41 | 28 | 2 | PF00856 | |
| Domain | PTB/PI_dom | 1.71e-03 | 41 | 28 | 2 | IPR006020 | |
| Domain | SET | 2.15e-03 | 46 | 28 | 2 | SM00317 | |
| Domain | SET_dom | 2.54e-03 | 50 | 28 | 2 | IPR001214 | |
| Domain | SET | 2.54e-03 | 50 | 28 | 2 | PS50280 | |
| Domain | PHD | 5.62e-03 | 75 | 28 | 2 | PF00628 | |
| Domain | Znf_PHD-finger | 6.22e-03 | 79 | 28 | 2 | IPR019787 | |
| Domain | PHD | 7.83e-03 | 89 | 28 | 2 | SM00249 | |
| Domain | Znf_PHD | 8.17e-03 | 91 | 28 | 2 | IPR001965 | |
| Domain | ZF_PHD_2 | 8.88e-03 | 95 | 28 | 2 | PS50016 | |
| Domain | ZF_PHD_1 | 9.06e-03 | 96 | 28 | 2 | PS01359 | |
| Domain | Cadherin_CS | 1.16e-02 | 109 | 28 | 2 | IPR020894 | |
| Domain | Cadherin | 1.24e-02 | 113 | 28 | 2 | PF00028 | |
| Domain | CADHERIN_1 | 1.24e-02 | 113 | 28 | 2 | PS00232 | |
| Domain | CADHERIN_2 | 1.26e-02 | 114 | 28 | 2 | PS50268 | |
| Domain | - | 1.26e-02 | 114 | 28 | 2 | 2.60.40.60 | |
| Domain | CA | 1.28e-02 | 115 | 28 | 2 | SM00112 | |
| Domain | Cadherin-like | 1.30e-02 | 116 | 28 | 2 | IPR015919 | |
| Domain | Cadherin | 1.34e-02 | 118 | 28 | 2 | IPR002126 | |
| Pubmed | Set1 and MLL1/2 Target Distinct Sets of Functionally Different Genomic Loci In Vivo. | 6.25e-07 | 2 | 28 | 2 | 26711341 | |
| Pubmed | 6.25e-07 | 2 | 28 | 2 | 24423662 | ||
| Pubmed | 1.87e-06 | 3 | 28 | 2 | 26902498 | ||
| Pubmed | Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia. | 1.87e-06 | 3 | 28 | 2 | 30315824 | |
| Pubmed | 1.87e-06 | 3 | 28 | 2 | 23932714 | ||
| Pubmed | 1.87e-06 | 3 | 28 | 2 | 31123786 | ||
| Pubmed | 1.87e-06 | 3 | 28 | 2 | 23192982 | ||
| Pubmed | 3.75e-06 | 4 | 28 | 2 | 22863532 | ||
| Pubmed | 3.75e-06 | 4 | 28 | 2 | 24081332 | ||
| Pubmed | 3.75e-06 | 4 | 28 | 2 | 37722486 | ||
| Pubmed | A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity. | 3.75e-06 | 4 | 28 | 2 | 23129768 | |
| Pubmed | 6.24e-06 | 5 | 28 | 2 | 26320581 | ||
| Pubmed | MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia. | 6.24e-06 | 5 | 28 | 2 | 28609655 | |
| Pubmed | 9.36e-06 | 6 | 28 | 2 | 34933446 | ||
| Pubmed | MLL associates specifically with a subset of transcriptionally active target genes. | 9.36e-06 | 6 | 28 | 2 | 16199523 | |
| Pubmed | Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs. | 9.36e-06 | 6 | 28 | 2 | 24176642 | |
| Pubmed | 1.31e-05 | 7 | 28 | 2 | 36598580 | ||
| Pubmed | 1.31e-05 | 7 | 28 | 2 | 19219072 | ||
| Pubmed | Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases. | 1.74e-05 | 8 | 28 | 2 | 23130995 | |
| Pubmed | 1.74e-05 | 8 | 28 | 2 | 22266653 | ||
| Pubmed | The mutational landscape of lethal castration-resistant prostate cancer. | 1.74e-05 | 8 | 28 | 2 | 22722839 | |
| Pubmed | 2.24e-05 | 9 | 28 | 2 | 22665483 | ||
| Pubmed | 2.24e-05 | 9 | 28 | 2 | 15960974 | ||
| Pubmed | Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression. | 2.24e-05 | 9 | 28 | 2 | 16951254 | |
| Pubmed | 2.24e-05 | 9 | 28 | 2 | 26691508 | ||
| Pubmed | Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2. | 2.24e-05 | 9 | 28 | 2 | 11247302 | |
| Pubmed | 2.24e-05 | 9 | 28 | 2 | 24930734 | ||
| Pubmed | 2.80e-05 | 10 | 28 | 2 | 12724416 | ||
| Pubmed | Human CpG binding protein interacts with MLL1, MLL2 and hSet1 and regulates Hox gene expression. | 3.42e-05 | 11 | 28 | 2 | 18082152 | |
| Pubmed | 4.10e-05 | 12 | 28 | 2 | 27563068 | ||
| Pubmed | 4.85e-05 | 13 | 28 | 2 | 16510874 | ||
| Pubmed | Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. | 6.52e-05 | 15 | 28 | 2 | 14992727 | |
| Pubmed | 6.52e-05 | 15 | 28 | 2 | 16510875 | ||
| Pubmed | 1.20e-04 | 119 | 28 | 3 | 23508102 | ||
| Pubmed | Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition. | 1.30e-04 | 21 | 28 | 2 | 27626377 | |
| Pubmed | 1.39e-04 | 125 | 28 | 3 | 29467281 | ||
| Pubmed | 1.39e-04 | 332 | 28 | 4 | 37433992 | ||
| Pubmed | 1.42e-04 | 638 | 28 | 5 | 31182584 | ||
| Pubmed | Structural basis for activity regulation of MLL family methyltransferases. | 1.43e-04 | 22 | 28 | 2 | 26886794 | |
| Pubmed | 1.58e-04 | 1049 | 28 | 6 | 27880917 | ||
| Pubmed | Interaction network of human early embryonic transcription factors. | 1.72e-04 | 351 | 28 | 4 | 38297188 | |
| Pubmed | SR protein kinases promote splicing of nonconsensus introns. | 1.92e-04 | 361 | 28 | 4 | 26167880 | |
| Pubmed | Identification and characterization of a novel human PP1 phosphatase complex. | 2.86e-04 | 31 | 28 | 2 | 20516061 | |
| Pubmed | 2.86e-04 | 31 | 28 | 2 | 15960975 | ||
| Pubmed | 3.05e-04 | 32 | 28 | 2 | 31815296 | ||
| Pubmed | A genome-wide association study (GWAS) for bronchopulmonary dysplasia. | 3.45e-04 | 34 | 28 | 2 | 23897914 | |
| Pubmed | Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression. | 3.68e-04 | 174 | 28 | 3 | 29669786 | |
| Pubmed | Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation. | 4.69e-04 | 457 | 28 | 4 | 32344865 | |
| Pubmed | 5.17e-04 | 469 | 28 | 4 | 27634302 | ||
| Pubmed | An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. | 5.45e-04 | 1321 | 28 | 6 | 27173435 | |
| Pubmed | 5.53e-04 | 43 | 28 | 2 | 33472061 | ||
| Pubmed | 6.27e-04 | 209 | 28 | 3 | 36779422 | ||
| Pubmed | 6.72e-04 | 503 | 28 | 4 | 16964243 | ||
| Pubmed | 7.48e-04 | 50 | 28 | 2 | 37974198 | ||
| Cytoband | Ensembl 112 genes in cytogenetic band chr13q22 | 6.63e-04 | 62 | 28 | 2 | chr13q22 | |
| GeneFamily | Zinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family | 4.59e-04 | 34 | 17 | 2 | 487 | |
| GeneFamily | PHD finger proteins | 3.17e-03 | 90 | 17 | 2 | 88 | |
| GeneFamily | Armadillo repeat containing|Protein phosphatase 1 regulatory subunits | 1.23e-02 | 181 | 17 | 2 | 694 | |
| GeneFamily | Zinc fingers C2H2-type|ZF class homeoboxes and pseudogenes | 2.80e-02 | 718 | 17 | 3 | 28 | |
| Coexpression | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN | 2.10e-06 | 200 | 28 | 5 | M4624 | |
| CoexpressionAtlas | FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000 | 3.01e-05 | 994 | 28 | 8 | Facebase_RNAseq_e8.5_Floor Plate_1000 | |
| CoexpressionAtlas | FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500 | 3.79e-05 | 495 | 28 | 6 | Facebase_RNAseq_e8.5_Floor Plate_500 | |
| ToppCell | droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype | 4.60e-06 | 179 | 28 | 4 | 4f20540bfbcefe0e83812be7ea542e8bb3bf19bc | |
| ToppCell | droplet-Lung-nan-21m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 4.60e-06 | 179 | 28 | 4 | d78eacf47847a50888dd16c35bed9b7afc80010f | |
| ToppCell | LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 5.83e-06 | 190 | 28 | 4 | 45df8fee00f8949937863159d7aa042e72748d9b | |
| ToppCell | 10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 6.07e-06 | 192 | 28 | 4 | 3ce5dbde41aeb73d49f2c7991d34682f0827fa5a | |
| ToppCell | frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype | 5.77e-05 | 120 | 28 | 3 | a4e3f9a83bc52ccc75bcd64b1be4e2c5441f6d1a | |
| ToppCell | TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9 | 8.19e-05 | 135 | 28 | 3 | ac20133d4a36f48338b45bffb13e842cb66f83ad | |
| ToppCell | primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype | 1.16e-04 | 152 | 28 | 3 | fed80b467ec9e30c7f98bed6cc4f8c583b715e9e | |
| ToppCell | renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 1.26e-04 | 156 | 28 | 3 | abf9dd075b1ca8f613c660cc82f8a5af071fb6ab | |
| ToppCell | renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 1.26e-04 | 156 | 28 | 3 | dd41ed918b07fa248da458a629b3c53cb7ea8764 | |
| ToppCell | wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung | 1.28e-04 | 157 | 28 | 3 | b9d04ee417c0d8ea0801d10f1c54e138587009fd | |
| ToppCell | Children_(3_yrs)-Mesenchymal-chondrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor | 1.28e-04 | 157 | 28 | 3 | f147e24f2ece82e1c54750868954d09b3c461804 | |
| ToppCell | frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype | 1.28e-04 | 157 | 28 | 3 | 516903469756c5fabfdf56d7bd59b3bdd7b44e39 | |
| ToppCell | PND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 1.38e-04 | 161 | 28 | 3 | 76c993a4533362db2250c88b3ee3ede55362d54e | |
| ToppCell | P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase | 1.38e-04 | 161 | 28 | 3 | b19f82dd98a3064581793711bb70373f18abecd9 | |
| ToppCell | PND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 1.38e-04 | 161 | 28 | 3 | 133b4fadb499e842c19f573f9cf09ce08c1d4813 | |
| ToppCell | PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 1.38e-04 | 161 | 28 | 3 | cb177ca10d848d0e25399ab5ebfcde1071fb94c2 | |
| ToppCell | PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 1.38e-04 | 161 | 28 | 3 | 9466b8658244116f8d21f2f88fb8c2d184b1bdf2 | |
| ToppCell | PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 1.41e-04 | 162 | 28 | 3 | 96c6e94a10b124a1d25dcd705ec5aaa8609c1089 | |
| ToppCell | P07-Endothelial-lymphatic_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase | 1.43e-04 | 163 | 28 | 3 | 5cbab3d03bb1af9391ecad635d6eea1dd42c1337 | |
| ToppCell | P07-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase | 1.43e-04 | 163 | 28 | 3 | 322ba94c3ec1e1859c2e2195ecb3f7dab8d190f6 | |
| ToppCell | primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype | 1.43e-04 | 163 | 28 | 3 | 8d17f44faf0549fe71a9a45f811f50d767275414 | |
| ToppCell | PND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass | 1.68e-04 | 172 | 28 | 3 | 9a659442dc41bd2a4361a7e38a7ee37a39781667 | |
| ToppCell | Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 1.95e-04 | 181 | 28 | 3 | 25915e2500430a902db37d79a749ce2990b69810 | |
| ToppCell | facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.95e-04 | 181 | 28 | 3 | 35eefd874a892eaf21f24fdce89e7ea3b8ee285f | |
| ToppCell | facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.95e-04 | 181 | 28 | 3 | e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968 | |
| ToppCell | renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 1.95e-04 | 181 | 28 | 3 | 5f2d3a08577c440c944778d07aa993c6e7873f3d | |
| ToppCell | renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 1.95e-04 | 181 | 28 | 3 | c7c5f7d4c397b4613c772413a0a679377efffff3 | |
| ToppCell | facs-Lung-EPCAM-3m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.01e-04 | 183 | 28 | 3 | ecac1cfaff7553a60305b34d6cede6973ffb5430 | |
| ToppCell | facs-Lung-EPCAM-3m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.01e-04 | 183 | 28 | 3 | f6ebfd7f61e912f92bd07313cc213a171747ac03 | |
| ToppCell | B_cells-ABCs|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues | 2.01e-04 | 183 | 28 | 3 | bf9c6fe3ce4e44e4056027257eab8448c39c4fb8 | |
| ToppCell | Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 2.08e-04 | 185 | 28 | 3 | e58a009aaf342be019a909747b1895d5987d4daf | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 2.08e-04 | 185 | 28 | 3 | 34fcfd635c828dad9643bbf1c908d79282d6f5d9 | |
| ToppCell | 343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|343B / Donor, Lineage, Cell class and subclass (all cells) | 2.08e-04 | 185 | 28 | 3 | d4ba36bdb8b7e3a62e827269484f89f790eaa5ef | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 2.08e-04 | 185 | 28 | 3 | 8816f2909ed11833ff3d0ed96b9cb6d6fe9e1578 | |
| ToppCell | Control-Myeloid-DC_Mature|Control / Disease state, Lineage and Cell class | 2.14e-04 | 187 | 28 | 3 | 049780ca2a3e6adcd89dc2cf3095b5ad068b244a | |
| ToppCell | 390C-Myeloid-Dendritic-cDC_activated|390C / Donor, Lineage, Cell class and subclass (all cells) | 2.14e-04 | 187 | 28 | 3 | 60c2576f31a60f819deb9ec500d1f714b469df4e | |
| ToppCell | Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 2.18e-04 | 188 | 28 | 3 | 4d1e5f85342ae550086609d7680e32730b78b5d2 | |
| ToppCell | -Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.18e-04 | 188 | 28 | 3 | 6468fa95ad0395395301115286f2d8c0df5d3882 | |
| ToppCell | -Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.18e-04 | 188 | 28 | 3 | 7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6 | |
| ToppCell | BAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 2.18e-04 | 188 | 28 | 3 | 9fc3819aae5a2b2534cb131d467435b5cfc420d6 | |
| ToppCell | -Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.18e-04 | 188 | 28 | 3 | 9cb718bfe1358c6fd842f096e228eb0abb9aefc6 | |
| ToppCell | BAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09) | 2.18e-04 | 188 | 28 | 3 | 5e5d779ea079d3b2a1ef650b06b9f5cc1ffef5e7 | |
| ToppCell | facs-Lung-EPCAM-18m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.21e-04 | 189 | 28 | 3 | 783c1db856f2defe6f3b8748dd0bc29a8102f6d1 | |
| ToppCell | facs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.21e-04 | 189 | 28 | 3 | 88b72fafbe58463543e0818f27f3dd9e5b4d34d2 | |
| ToppCell | facs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype | 2.25e-04 | 190 | 28 | 3 | 47e07ea22733306d8885ee9e5f0b033e2f5e2afb | |
| ToppCell | facs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype | 2.25e-04 | 190 | 28 | 3 | 261b8afddfdcba4f70b50df126cef7ad00a0aae0 | |
| ToppCell | kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 2.25e-04 | 190 | 28 | 3 | b855b8b7d3439023390ca44629c1a99f5d4c6801 | |
| ToppCell | Mesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor | 2.25e-04 | 190 | 28 | 3 | 645e56b02edc3702c7db917b8ecd5eed0decaf71 | |
| ToppCell | LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.32e-04 | 192 | 28 | 3 | f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b | |
| ToppCell | LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.32e-04 | 192 | 28 | 3 | df1545670370fb1010c567cd059c2783eab315f7 | |
| ToppCell | BAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09) | 2.35e-04 | 193 | 28 | 3 | a2194012dfa0174c6160900625c44e0fd04c50e7 | |
| ToppCell | BAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 2.35e-04 | 193 | 28 | 3 | 7426a30ed01e5c8376b3e0ebe0f1057cfee88340 | |
| ToppCell | PCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung | 2.35e-04 | 193 | 28 | 3 | 000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6 | |
| ToppCell | kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 2.35e-04 | 193 | 28 | 3 | 0f2167eef8203a5659c8c72e4e77646003d64797 | |
| ToppCell | Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor | 2.35e-04 | 193 | 28 | 3 | 99525545552b371c86b18b6ea6f4897dc6e9a9ec | |
| ToppCell | Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor | 2.35e-04 | 193 | 28 | 3 | b3ad5ff480d99217f36cc7471e5a96a519ddb409 | |
| ToppCell | 3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 2.39e-04 | 194 | 28 | 3 | 7b6a34d1f8922b71dcc931421666c1822cec8345 | |
| ToppCell | Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor | 2.39e-04 | 194 | 28 | 3 | e93de9428c986b8943fc169258847c650cfab0e5 | |
| ToppCell | 3'_v3-Lung-Mast|Lung / Manually curated celltypes from each tissue | 2.39e-04 | 194 | 28 | 3 | 5e6eb81ddc9d5e22c1297734689f476d5a05bff6 | |
| ToppCell | (4)_Endothelial_cells-(42)_EC-sinusoidal|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis | 2.39e-04 | 194 | 28 | 3 | 4199900d16623eca02d674d5ada7f0989e47955e | |
| ToppCell | kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 2.39e-04 | 194 | 28 | 3 | 8ddcaaf24cee6e30d5be52c0cbf778cfba309c53 | |
| ToppCell | 367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|367C / Donor, Lineage, Cell class and subclass (all cells) | 2.39e-04 | 194 | 28 | 3 | e3688f4252aae5f849f025d7f453ff4c0c14590b | |
| ToppCell | 3'_v3-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue | 2.39e-04 | 194 | 28 | 3 | 7b7f1714c4a9d9519c4d0e460cb87f2eb82392dd | |
| ToppCell | 3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 2.39e-04 | 194 | 28 | 3 | 435406ebe626c702f7d5a99a3d68ee85aa09be95 | |
| ToppCell | 3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 2.39e-04 | 194 | 28 | 3 | 48c37251518f96524807b5bd1bbc2820637666ad | |
| ToppCell | Monocytes-C1QA+_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues | 2.39e-04 | 194 | 28 | 3 | 3e104e85574894c04791252d466d438fc809dde3 | |
| ToppCell | PCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung | 2.39e-04 | 194 | 28 | 3 | 67f5e2f05a8de2213ab80d5ea16fdee121684633 | |
| ToppCell | BAL|World / Compartment, Disease Groups and Clusters | 2.42e-04 | 195 | 28 | 3 | f59faf77fc7d7fd7ddb9d4d6d469951d5066bebb | |
| ToppCell | 390C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells) | 2.42e-04 | 195 | 28 | 3 | ecf7d9856a5b507ec17c325c9a772dc5a184bc8e | |
| ToppCell | saliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 2.42e-04 | 195 | 28 | 3 | a65441ab3ee1949ec14db1d2d03bb1ee80d389bd | |
| ToppCell | Mild/Remission-B_naive-8|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5) | 2.42e-04 | 195 | 28 | 3 | 0a3221e4d1fa31a35868bdda0f0cc873c233b407 | |
| ToppCell | COVID-19_Mild-PLT_5|COVID-19_Mild / Disease Group and Platelet Clusters | 2.42e-04 | 195 | 28 | 3 | bdf9a6ea1bd83c72a834c45f86ce3f4643a9bef3 | |
| ToppCell | ILEUM-inflamed-(3)_Resident_macrophages|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2) | 2.46e-04 | 196 | 28 | 3 | 5ac246a823a8e1996325753858615269687b429d | |
| ToppCell | ILEUM-non-inflamed-(3)_Resident_macrophages|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2) | 2.50e-04 | 197 | 28 | 3 | 3af24354b6a93c7d105b9fa6549cf215107b9203 | |
| ToppCell | Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 2.50e-04 | 197 | 28 | 3 | 032ccc91e604113da9bc34a6f9ddb1d45dea1892 | |
| ToppCell | (3)_Macrophage_MARCOneg|World / Lung cell shreds - cell class (v4) and cell subclass (v4) | 2.50e-04 | 197 | 28 | 3 | b0ee2ce1179b60b4542559acb300a34295277dbc | |
| ToppCell | MS-mono1|MS / Condition, Cell_class and T cell subcluster | 2.50e-04 | 197 | 28 | 3 | 32be48ee2a1397ed8f1ee8e60067dd9a96bece39 | |
| ToppCell | MS-mono1-|MS / Condition, Cell_class and T cell subcluster | 2.50e-04 | 197 | 28 | 3 | 4b038a193ecc1df65bcb608091c513ddafd6c818 | |
| ToppCell | 10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 2.50e-04 | 197 | 28 | 3 | 82b8e22317cad6d3786bd70d91107007c0ccd7cd | |
| ToppCell | COVID-19-Myeloid-Migratory_DC|COVID-19 / Condition, Lineage and Cell class | 2.50e-04 | 197 | 28 | 3 | b6d6cdae33753c1e38394f1f879e00b87f9c0496 | |
| ToppCell | IPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class | 2.50e-04 | 197 | 28 | 3 | f304d42fc4936fe20996e07c8dccc698a6e5e5ef | |
| ToppCell | 3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 2.54e-04 | 198 | 28 | 3 | 93cc01d91ffc543fd1a717ef47e02e532b50b665 | |
| ToppCell | wk_15-18-Mesenchymal-Myofibro_&_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung | 2.54e-04 | 198 | 28 | 3 | c9c96066c7fa897b583657f0b77ea093920ae9ba | |
| ToppCell | 10x_5'_v1-Non-neoplastic-Myeloid|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 2.54e-04 | 198 | 28 | 3 | e1a0c809302a3b304775bd708201ad412a98d711 | |
| ToppCell | Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster | 2.54e-04 | 198 | 28 | 3 | de5214a85fe017eb23d4aa8af624464f062ec57e | |
| ToppCell | BAL-Severe-Myeloid-MoAM-MoAM1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09) | 2.57e-04 | 199 | 28 | 3 | 362da30f3a88b003103796c56782be0dfd6705a9 | |
| ToppCell | BAL-Severe-Myeloid-MoAM-MoAM1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 2.57e-04 | 199 | 28 | 3 | 29dc81a98bd3fa86380cc642a23e9084fec05cab | |
| ToppCell | BAL-Mild-Myeloid-TRAM-TRAM3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 2.57e-04 | 199 | 28 | 3 | 4e518651ff219e163cfd9deb58566df6308aa3f7 | |
| ToppCell | 10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 2.57e-04 | 199 | 28 | 3 | 994e885b8d1874006302a081d13f1ee881d64612 | |
| ToppCell | 10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 2.57e-04 | 199 | 28 | 3 | f965eb89d6d023c83154276b8fded490fd89c100 | |
| ToppCell | BAL-Mild-Myeloid|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09) | 2.57e-04 | 199 | 28 | 3 | 0f0fcc6fb980167cfa9aa404b845441fb95a08f4 | |
| ToppCell | 10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type | 2.57e-04 | 199 | 28 | 3 | c0dcdda30485bb920d3706dcfb06f11b76b6ea37 | |
| ToppCell | Mild_COVID-19-Myeloid-TRAM3|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30) | 2.57e-04 | 199 | 28 | 3 | 4ab5da8ab757e8294c743949a5374b6e6a388913 | |
| ToppCell | Severe_COVID-19-Myeloid-MoAM1|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30) | 2.57e-04 | 199 | 28 | 3 | 8895332f0026e59cd19f41de0ef014f7b2af74e1 | |
| ToppCell | BAL-Mild-Myeloid-TRAM-TRAM3-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 2.57e-04 | 199 | 28 | 3 | af167e7a16c3537ce0aa821f608cdcb0c3abc07f | |
| ToppCell | Bronchial-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations | 2.57e-04 | 199 | 28 | 3 | a1ff1063741f6e5569feb44245785c9f472799b2 | |
| ToppCell | 10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type | 2.57e-04 | 199 | 28 | 3 | b827dd8a249f904a0ff930a6c4d3b00fb7bc6fb1 | |
| ToppCell | BAL-Mild-Myeloid-TRAM-TRAM3-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09) | 2.57e-04 | 199 | 28 | 3 | 4b88ce864dc75ed8596a076ce4498f73639bbac8 | |
| ToppCell | 10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type | 2.57e-04 | 199 | 28 | 3 | 80ed217d28ba1c07facd0e103c25a02658dd848d | |
| ToppCell | BAL-Mild-Myeloid-TRAM|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09) | 2.57e-04 | 199 | 28 | 3 | 8a31a459491aa8625802c5211d38d57c1e8be76b | |
| Drug | Ketoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A | 3.95e-06 | 198 | 28 | 5 | 2316_UP | |
| Disease | lung small cell carcinoma (is_implicated_in) | 2.78e-04 | 28 | 26 | 2 | DOID:5409 (is_implicated_in) | |
| Disease | Burkitt Lymphoma | 4.62e-04 | 36 | 26 | 2 | C0006413 | |
| Disease | airway imaging measurement | 5.15e-04 | 38 | 26 | 2 | EFO_0007627 | |
| Disease | esophagus squamous cell carcinoma (is_implicated_in) | 7.22e-04 | 45 | 26 | 2 | DOID:3748 (is_implicated_in) | |
| Disease | bronchopulmonary dysplasia | 7.22e-04 | 45 | 26 | 2 | MONDO_0019091 | |
| Disease | Gastrointestinal Stromal Sarcoma | 7.88e-04 | 47 | 26 | 2 | C3179349 | |
| Disease | Gastrointestinal Stromal Tumors | 8.91e-04 | 50 | 26 | 2 | C0238198 | |
| Disease | Alzheimer's disease (implicated_via_orthology) | 1.16e-03 | 57 | 26 | 2 | DOID:10652 (implicated_via_orthology) | |
| Disease | congenital heart disease (implicated_via_orthology) | 1.69e-03 | 69 | 26 | 2 | DOID:1682 (implicated_via_orthology) | |
| Disease | p-tau measurement | 1.84e-03 | 72 | 26 | 2 | EFO_0004763 | |
| Disease | Liver Dysfunction | 1.84e-03 | 72 | 26 | 2 | C0086565 | |
| Disease | Liver diseases | 1.84e-03 | 72 | 26 | 2 | C0023895 | |
| Disease | esophagus squamous cell carcinoma (is_marker_for) | 1.94e-03 | 74 | 26 | 2 | DOID:3748 (is_marker_for) | |
| Disease | Neurodevelopmental Disorders | 3.04e-03 | 93 | 26 | 2 | C1535926 | |
| Disease | Squamous cell carcinoma of esophagus | 3.17e-03 | 95 | 26 | 2 | C0279626 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| RPIFFPDVDPHSLPP | 271 | Q8N4J0 | |
| ERPSHPLYEPEPEPR | 191 | Q5TGY3 | |
| HPPPLLEDEEPDFVP | 636 | Q9NVE4 | |
| PFSIELEDPQPPPDH | 231 | P42081 | |
| AVDPDEPIHGPPFDF | 596 | Q02487 | |
| EDFRHPPDEDFRGPP | 801 | Q8IXT5 | |
| FRGPPDEDFRHPPDE | 811 | Q8IXT5 | |
| DEPEEPPAHRPEREF | 1351 | Q9Y4B5 | |
| EESEEIPPFHPFHPF | 591 | Q06481 | |
| FFPTPNPDPFRDDPF | 286 | P98082 | |
| DFPAADELPPLPPEF | 4441 | Q14517 | |
| DELLDPDMDPPHPFP | 66 | P51798 | |
| PTPLDPHEPERPFFE | 586 | Q86V87 | |
| PSFRELPPPPLELFD | 341 | Q9Y366 | |
| PIFDNFRPPPLTPED | 646 | Q03164 | |
| FPPVLHGDPEIFEAP | 396 | O75881 | |
| IVHEDAPAPPPEDFP | 81 | Q9BXA9 | |
| HFPPEPGPPEKTEDE | 341 | Q9BT04 | |
| EEEFDHLPPPQPRLP | 326 | Q8ND83 | |
| DPFPFFPEPRAPESE | 1036 | Q9H2D6 | |
| FPEPRAPESEPPHHE | 1041 | Q9H2D6 | |
| PPRHTQFDPFPFLPD | 1076 | Q9H2D6 | |
| IESHFRPEFIRPPPP | 276 | Q9UKZ1 | |
| EDPPPFVEPSSEHPL | 336 | Q5T1R4 | |
| CIQDEPFPHPLEPEP | 6 | O60343 | |
| AFPELHPRPNPEEKP | 46 | O15090 | |
| PKQEEHAFESPPPPD | 236 | Q5T4F4 | |
| KESPHEPDPEPYEPI | 501 | Q96QC0 | |
| FHELPETFPSDPPEP | 46 | O95185 | |
| DPPEPLPHFLIEPEE | 56 | O95185 | |
| EHVEDETFPPFPPPA | 16 | Q9BVW5 | |
| SPPPEASRLFPPFEE | 591 | O14686 |