Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

VIL1 EPS15 EFCAB6 CIB3 PCDHB14 CDH19 TBC1D8B PKDREJ SYT7 DNAH7 IQGAP1 CRB1 BMP1 MYOF NECAB1 ACAN AOC3 MACF1 CDH12 RHOT1

3.26e-0674916320GO:0005509
GeneOntologyMolecularFunctionATP-dependent activity

MYH2 ABCA2 ATP6V0A1 DDX12P DNAH10 YTHDC2 INO80 DNAH7 DDX27 HELB ERCC6L2 MACF1 DDX20 ATP1A1 DNAH8 KIF22 AFG1L

1.17e-0561416317GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA2 DDX12P DNAH10 YTHDC2 INO80 DNAH7 DDX27 HELB MACF1 DDX20 ATP1A1 DNAH8 KIF22 AFG1L

1.62e-0544116314GO:0016887
GeneOntologyMolecularFunctionhistone H2AXS139 kinase activity

ATR PRKDC

1.98e-0431632GO:0035979
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ABCA2 DDX12P DNAH10 YTHDC2 INO80 DNAH7 DDX27 HELB EFTUD2 GUF1 MACF1 DDX20 ATP1A1 DNAH8 RHOT1 KIF22 AFG1L

2.08e-0477516317GO:0017111
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH10 DNAH7 DNAH8

3.98e-04181633GO:0008569
GeneOntologyMolecularFunctionpyrophosphatase activity

ABCA2 DDX12P DNAH10 YTHDC2 INO80 DNAH7 DDX27 HELB EFTUD2 GUF1 MACF1 DDX20 ATP1A1 DNAH8 RHOT1 KIF22 AFG1L

5.18e-0483916317GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ABCA2 DDX12P DNAH10 YTHDC2 INO80 DNAH7 DDX27 HELB EFTUD2 GUF1 MACF1 DDX20 ATP1A1 DNAH8 RHOT1 KIF22 AFG1L

5.25e-0484016317GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ABCA2 DDX12P DNAH10 YTHDC2 INO80 DNAH7 DDX27 HELB EFTUD2 GUF1 MACF1 DDX20 ATP1A1 DNAH8 RHOT1 KIF22 AFG1L

5.25e-0484016317GO:0016818
GeneOntologyMolecularFunctionhistone H2AX kinase activity

ATR PRKDC

6.52e-0451632GO:0141003
GeneOntologyMolecularFunction2'-5'-oligoadenylate synthetase activity

OAS3 OASL

6.52e-0451632GO:0001730
GeneOntologyCellularComponentmicrotubule

EFCAB6 DNAH10 CLASP1 RIBC2 TOGARAM2 GABARAP INO80 DCTN1 DNAH7 IQGAP1 TPX2 MACF1 DNAH8 KIF22

7.25e-0553316214GO:0005874
DomainFAT

ATR TRRAP PRKDC

1.23e-0561613PS51189
DomainFATC

ATR TRRAP PRKDC

1.23e-0561613PS51190
DomainFAT

ATR TRRAP PRKDC

1.23e-0561613PF02259
DomainPIK-rel_kinase_FAT

ATR TRRAP PRKDC

1.23e-0561613IPR003151
DomainFATC_dom

ATR TRRAP PRKDC

1.23e-0561613IPR003152
DomainPIK_FAT

ATR TRRAP PRKDC

1.23e-0561613IPR014009
DomainFATC

ATR TRRAP PRKDC

1.23e-0561613SM01343
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH7 DNAH8

2.13e-04141613IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH7 DNAH8

2.13e-04141613IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH7 DNAH8

2.13e-04141613IPR013602
DomainDHC_N2

DNAH10 DNAH7 DNAH8

2.13e-04141613PF08393
DomainMT

DNAH10 DNAH7 DNAH8

2.13e-04141613PF12777
DomainAAA_8

DNAH10 DNAH7 DNAH8

2.13e-04141613PF12780
DomainDHC_fam

DNAH10 DNAH7 DNAH8

2.65e-04151613IPR026983
DomainDynein_heavy

DNAH10 DNAH7 DNAH8

2.65e-04151613PF03028
DomainDynein_heavy_dom

DNAH10 DNAH7 DNAH8

2.65e-04151613IPR004273
Domain-

ATR TRRAP PRKDC

3.24e-041616131.10.1070.11
DomainPI3Kc

ATR TRRAP PRKDC

3.24e-04161613SM00146
DomainP-loop_NTPase

MYH2 ABCA2 DNAH10 YTHDC2 INO80 DNAH7 DDX27 IQGAP1 HELB EFTUD2 NDST3 GUF1 ERCC6L2 DDX20 DNAH8 RHOT1 KIF22 AFG1L

3.85e-0484816118IPR027417
DomainOAS1_C

OAS3 OASL

4.38e-0441612PF10421
Domain2-5-oligoadenylate_synth_CS

OAS3 OASL

4.38e-0441612IPR006117
Domain25A_SYNTH_3

OAS3 OASL

4.38e-0441612PS50152
DomainCLASP_N

CLASP1 TOGARAM2

4.38e-0441612PF12348
DomainCLASP_N_dom

CLASP1 TOGARAM2

4.38e-0441612IPR024395
Domain2-5-oligoAdlate_synth_1_dom2/C

OAS3 OASL

4.38e-0441612IPR018952
Domain2-5A_synthase

OAS3 OASL

4.38e-0441612IPR026774
Domain-

OAS3 OASL

4.38e-04416121.10.1410.20
Domain25A_SYNTH_1

OAS3 OASL

4.38e-0441612PS00832
Domain25A_SYNTH_2

OAS3 OASL

4.38e-0441612PS00833
DomainPI3_PI4_kinase

ATR TRRAP PRKDC

4.66e-04181613PF00454
DomainPI3_4_KINASE_1

ATR TRRAP PRKDC

4.66e-04181613PS00915
DomainPI3_4_KINASE_2

ATR TRRAP PRKDC

4.66e-04181613PS00916
DomainPI3/4_kinase_cat_dom

ATR TRRAP PRKDC

4.66e-04181613IPR000403
DomainPI3_4_KINASE_3

ATR TRRAP PRKDC

4.66e-04181613PS50290
Domain2-5-oligoadenylate_synth_N

OAS3 OASL

7.26e-0451612IPR006116
DomainFATC

ATR PRKDC

7.26e-0451612PF02260
DomainARM-type_fold

ATR CLASP1 NBEAL1 TOGARAM2 TRRAP FOCAD PPP4R3B NOM1 ANKAR PRKDC

7.34e-0433916110IPR016024
DomainEF_Hand_1_Ca_BS

EPS15 EFCAB6 CIB3 DNAH7 NECAB1 MACF1 RHOT1

8.18e-041751617IPR018247
DomainEF_hand_dom

EPS15 EFCAB6 CIB3 TBC1D8B DNAH7 NECAB1 MACF1 RHOT1

9.26e-042321618IPR002048
DomainEFG_C

EFTUD2 GUF1

1.08e-0361612PF00679
DomainEFG_III-V

EFTUD2 GUF1

1.08e-0361612IPR009022
DomainEFG_C

EFTUD2 GUF1

1.08e-0361612SM00838
DomainUIM

UIMC1 EPS15 MNAT1

1.11e-03241613PS50330
DomainUIM_dom

UIMC1 EPS15 MNAT1

1.26e-03251613IPR003903
Domain-

EFTUD2 GUF1

1.51e-03716123.30.70.240
DomainEFG_V

EFTUD2 GUF1

1.51e-0371612IPR000640
Domain-

EPS15 EFCAB6 CIB3 TBC1D8B STAT2 NECAB1 MACF1 RHOT1

1.95e-0326116181.10.238.10
DomainEF_HAND_1

EPS15 EFCAB6 CIB3 TBC1D8B NECAB1 MACF1 RHOT1

1.98e-032041617PS00018
DomainEphrin

EFNA4 EFNB1

2.00e-0381612PF00812
DomainDHC_N1

DNAH10 DNAH8

2.00e-0381612PF08385
DomainEphrin_RBD

EFNA4 EFNB1

2.00e-0381612IPR001799
DomainEphrin

EFNA4 EFNB1

2.00e-0381612PD002533
DomainEphrin

EFNA4 EFNB1

2.00e-0381612IPR031328
DomainEPHRIN_RBD_1

EFNA4 EFNB1

2.00e-0381612PS01299
DomainEphrin_CS

EFNA4 EFNB1

2.00e-0381612IPR019765
DomainEPHRIN_RBD_2

EFNA4 EFNB1

2.00e-0381612PS51551
DomainDynein_heavy_dom-1

DNAH10 DNAH8

2.00e-0381612IPR013594
Domain-

ABCA2 DNAH10 YTHDC2 INO80 DNAH7 DDX27 HELB EFTUD2 NDST3 GUF1 ERCC6L2 DDX20 DNAH8 RHOT1 AFG1L

2.03e-03746161153.40.50.300
DomainHelicase_C

YTHDC2 INO80 DDX27 ERCC6L2 DDX20

2.35e-031071615PF00271
DomainHELICc

YTHDC2 INO80 DDX27 ERCC6L2 DDX20

2.35e-031071615SM00490
DomainHelicase_C

YTHDC2 INO80 DDX27 ERCC6L2 DDX20

2.44e-031081615IPR001650
DomainEFh

EPS15 EFCAB6 CIB3 NECAB1 MACF1 RHOT1

2.50e-031581616SM00054
DomainHELICASE_CTER

YTHDC2 INO80 DDX27 ERCC6L2 DDX20

2.54e-031091615PS51194
DomainHELICASE_ATP_BIND_1

YTHDC2 INO80 DDX27 ERCC6L2 DDX20

2.54e-031091615PS51192
DomainDEXDc

YTHDC2 INO80 DDX27 ERCC6L2 DDX20

2.54e-031091615SM00487
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

VIL1 MYH2 ACACA CLASP1 HNRNPM LARP1 GABARAP EXT2 DCTN1 TRRAP GDI1 DDX27 IQGAP1 CRB1 EFTUD2 PPP4R3B SRRT LIG3 NAA25 EIF2B1 NOM1 MKLN1 AFDN DDX20 DEDD MNAT1

3.90e-1012841642617353931
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

UIMC1 ACACA ATR CLASP1 LARP1 SEMA5A YTHDC2 TRRAP ADARB1 IQGAP1 EFTUD2 FANCD2 SRRT MYOF ZNF516 TPX2 AFDN DDX20 PRKDC DNMBP

8.44e-107741642015302935
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

UIMC1 EPS15 MACC1 CLASP1 YTHDC2 INO80 TRRAP SYT7 DDX27 RRP1 IQGAP1 INTS10 SRRT MYOF GUF1 GTF2H1 CYFIP1 NOM1 TPX2 MRPS23 RBM5 MACF1 AFDN DDX20 DNMBP MNAT1 KIF22

2.12e-0914971642731527615
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ABCA2 ATP6V0A1 FOLH1 ADGRB3 DCTN1 GDI1 ADARB1 DDX27 IQGAP1 FOCAD PPP4R3B GUF1 FRY NAA25 SACS NECAB1 MKLN1 MACF1 AFDN PRKDC MNAT1 TRIM37 USP33 LGI1

9.48e-0912851642435914814
Pubmed

Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype.

KIR3DL1 KIR3DL2 KIR3DS1

1.03e-073164311859120
Pubmed

Analysis of killer immunoglobulin-like receptor genes in ankylosing spondylitis.

KIR3DL1 KIR3DL2 KIR3DS1

1.03e-073164319019897
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ATP6V0A1 ACACA ATR DNAH10 HNRNPM POR LARP1 YTHDC2 DCTN1 DDX27 RRP1 IQGAP1 EFTUD2 FANCD2 SRRT LIG3 CYFIP1 EIF2B1 RBM5 AFDN DDX20 PRKDC ATP1A1

2.72e-0714251642330948266
Pubmed

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.

KIR3DL1 KIR3DL2 KIR3DS1

4.10e-074164327455421
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

EPS15 ACACA CLASP1 HNRNPM OAS3 ITGAM DCTN1 GDI1 APOBEC3B RRP1 IQGAP1 EFTUD2 TXNL1 MYOF NAA25 CYFIP1 MRPS23 AFDN DDX20 PRKDC GPNMB ATP1A1

5.32e-0713671642232687490
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

RPAP3 HNRNPM LARP1 OAS3 YTHDC2 ARHGAP11A GDI1 DDX27 APOBEC3B RRP1 IQGAP1 EFTUD2 SRRT MYOF GTF2H1 CYFIP1 NOM1 TPX2 OASL MRPS23 PRKDC

5.43e-0712571642136526897
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

CLASP1 HNRNPM LARP1 YTHDC2 TRRAP DDX27 RRP1 IQGAP1 SRRT LIG3 EIF2B1 NOM1 TPX2 MACF1 PRKDC KIF22

6.96e-077591641635915203
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

MYH2 EPS15 ATP6V0A1 ABL2 ATR CLASP1 GABARAP DCTN1 TRRAP SGK3 MYOF GTF2H1 CYFIP1 EIF2B1 TPX2 ERRFI1 MNAT1

1.60e-069101641736736316
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ACACA RPAP3 HNRNPM OAS3 DCTN1 TRRAP DDX27 IQGAP1 LGALS7 EFTUD2 SRRT LIG3 GUF1 GTF2H1 CYFIP1 ARHGEF1 MRPS23 MACF1 AFDN DDX20 PRKDC

1.75e-0613531642129467282
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

UIMC1 ATR DSN1 FANCD2 SRRT LIG3 GTF2H1 TPX2 RBM5 SMARCD3 DDX20 MNAT1

1.81e-064531641229656893
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

AMER1 UBE2L6 ACACA WWC3 HNRNPM LARP1 DCTN1 GDI1 SYT7 DDX27 RRP1 IQGAP1 EFTUD2 SRRT LIG3 MYOF CYFIP1 PRKDC ATP1A1 KIF22

1.93e-0612471642027684187
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ACACA LARP1 YTHDC2 TRRAP GDI1 DDX27 RRP1 IQGAP1 OASL MACF1 AFDN DDX20 PRKDC ATP1A1

2.94e-066531641422586326
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

EPS15 AMER1 ACACA EFCAB6 HNRNPM POR DNAH7 CRB1 EFTUD2 EFNB1 NOM1 RBM5 AFDN PRKDC ATP1A1

4.59e-067771641535844135
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

ATR HNRNPM DTX3L IQGAP1 EFTUD2 LIG3 MYOF TPX2 PRKDC MNAT1

5.42e-063401641024332808
Pubmed

Human diversity in killer cell inhibitory receptor genes.

KIR3DL1 KIR3DL2 KIR3DS1

5.67e-06816439430221
Pubmed

Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.

HNRNPM LARP1 AFDN PRKDC ATP1A1

5.75e-0654164525631074
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

ACACA HNRNPM DCTN1 IQGAP1 EFTUD2 FOCAD CYFIP1 MRPS23 PRKDC ATP1A1

6.00e-063441641036282215
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

ACACA HNRNPM YTHDC2 TRIM24 DCTN1 TRRAP IQGAP1 FANCD2 CYFIP1 MRPS23 PRKDC ATP1A1 DNAH8 RHOT1

6.92e-067041641429955894
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

EPS15 ABL2 RPAP3 HNRNPM LARP1 YTHDC2 IQGAP1 TXNL1 CYFIP1 MACF1 AFDN PRKDC CRYBG3 ATP1A1

7.37e-067081641439231216
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR3DL1 KIR3DL2 KIR3DS1

8.47e-06916438662091
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

ASNSD1 UIMC1 RPAP3 HNRNPM LARP1 DSN1 EFTUD2 SRRT TPX2 KIF22

9.14e-063611641030344098
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

VIL1 CYP26B1 ACACA PCDHB14 LAMA1 HNRNPM LARP1 ARHGAP11A FOCAD LIG3 FRY ERRFI1 PRKDC MTMR9

1.14e-057361641429676528
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

UIMC1 HNRNPM LARP1 GABARAP DCTN1 DDX27 RRP1 IQGAP1 EFTUD2 EIF2B1 NOM1 TPX2 DDX20 PRKDC ATP1A1 KIF22

1.19e-059491641636574265
Pubmed

Tel2 regulates the stability of PI3K-related protein kinases.

ATR TRRAP PRKDC

1.21e-0510164318160036
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

HNRNPM LARP1 INO80 DCTN1 TRRAP DDX27 RRP1 EFTUD2 CYFIP1 NOM1 TPX2 MRPS23 RBM5 DDX20 PRKDC

1.27e-058471641535850772
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ATP6V0A1 CLASP1 HNRNPM POR LARP1 YTHDC2 DCTN1 GDI1 IQGAP1 SRRT CYFIP1 SACS ARHGEF1 KCNQ3 MACF1 AFDN ATP1A1 CACNA2D3 RHOT1 LGI1

1.47e-0514311642037142655
Pubmed

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

HNRNPM LARP1 OAS3 YTHDC2 ADARB1 RRP1 IQGAP1 EFTUD2 CYFIP1 MRPS23 ATP1A1

1.54e-054691641137314180
Pubmed

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.

ATR TRRAP PRKDC

1.65e-0511164320427287
Pubmed

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.

ATR LIG3 PRKDC

1.65e-0511164315758953
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

INO80 DCTN1 TRRAP DDX27 RRP1 LIG3 TPX2 PRKDC ATP1A1 KIF22

1.94e-053941641027248496
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].

KIR3DL1 KIR3DL2 KIR3DS1

2.20e-0512164317490516
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR3DL1 KIR3DL2 KIR3DS1

2.20e-0512164320137308
Pubmed

Targeting an Achilles' heel of cancer with a WRN helicase inhibitor.

FANCD2 PRKDC

2.21e-052164224036544
Pubmed

No association of KIR3DL1 or KIR3DS1 or their alleles with ankylosing spondylitis.

KIR3DL1 KIR3DS1

2.21e-052164219874556
Pubmed

Evaluation of KIR3DL1/KIR3DS1 polymorphism in Behçet's disease.

KIR3DL1 KIR3DS1

2.21e-052164227708262
Pubmed

DNA structure-specific priming of ATR activation by DNA-PKcs.

ATR PRKDC

2.21e-052164223897887
Pubmed

Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism.

KIR3DL1 KIR3DL2

2.21e-052164211207248
Pubmed

Investigation of killer cell immunoglobulin-like receptor gene diversity in KIR3DL1 and KIR3DS1 in a transplant population.

KIR3DL1 KIR3DS1

2.21e-052164218331531
Pubmed

Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations.

KIR3DL1 KIR3DS1

2.21e-052164216805919
Pubmed

Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro.

KIR3DL1 KIR3DS1

2.21e-052164219211742
Pubmed

Transfer of type II collagen-induced arthritis from DBA/1 to severe combined immunodeficiency mice can be prevented by blockade of Mac-1.

ITGAM PRKDC

2.21e-05216428690467
Pubmed

Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1.

KIR3DL1 KIR3DS1

2.21e-052164235192601
Pubmed

Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma.

KIR3DL1 KIR3DS1

2.21e-052164237647275
Pubmed

Association of the KIR3DS1*013 and KIR3DL1*004 alleles with susceptibility to ankylosing spondylitis.

KIR3DL1 KIR3DS1

2.21e-052164220131260
Pubmed

Protective genotypes in HIV infection reflect superior function of KIR3DS1+ over KIR3DL1+ CD8+ T cells.

KIR3DL1 KIR3DS1

2.21e-052164225112829
Pubmed

Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans.

KIR3DL1 KIR3DS1

2.21e-052164217694054
Pubmed

New insights into ATR inhibition in muscle invasive bladder cancer: The role of apolipoprotein B mRNA editing catalytic subunit 3B.

ATR APOBEC3B

2.21e-052164238827321
Pubmed

Contribution of functional KIR3DL1 to ankylosing spondylitis.

KIR3DL1 KIR3DS1

2.21e-052164220818412
Pubmed

KIR3DL1 and KIR3DL2 gene copy number variation in axial spondyloarthritis.

KIR3DL1 KIR3DL2

2.21e-052164225940819
Pubmed

Human osteosarcoma expresses specific ephrin profiles: implications for tumorigenicity and prognosis.

EFNA4 EFNB1

2.21e-052164212209731
Pubmed

Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer.

KIR3DL1 KIR3DL2

2.21e-05216428777725
Pubmed

A method for killer-cell immunoglobulin-like receptor (KIR) 3DL1/3DS1 genotyping using DNA recovered from frozen plasma.

KIR3DL1 KIR3DS1

2.21e-052164223524032
Pubmed

Diversity of the p70 killer cell inhibitory receptor (KIR3DL) family members in a single individual.

KIR3DL1 KIR3DL2

2.21e-052164210774747
Pubmed

Role of gamma delta T cells in the inflammatory response of experimental colitis mice.

PRKDC IL7R

2.21e-052164214607957
Pubmed

Allele diversity of the killer cell immunoglobulin-like receptors KIR3DL1/S1 and the combination with their HLA ligands in Mexican Mestizos from Mexico City.

KIR3DL1 KIR3DS1

2.21e-052164230365992
Pubmed

Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells.

KIR3DL1 KIR3DS1

2.21e-052164217182560
Pubmed

Genetic control of variegated KIR gene expression: polymorphisms of the bi-directional KIR3DL1 promoter are associated with distinct frequencies of gene expression.

KIR3DL1 KIR3DS1

2.21e-052164219008943
Pubmed

HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection.

KIR3DL1 KIR3DS1

2.21e-052164219386717
Pubmed

Putative role of KIR3DL1/3DS1 alleles and HLA-Bw4 ligands with end stage renal disease and long term renal allograft survival.

KIR3DL1 KIR3DS1

2.21e-052164228942035
Pubmed

The profile of KIR3DL1 and KIR3DS1 alleles in an African American population resembles that found in African populations.

KIR3DL1 KIR3DS1

2.21e-052164220230527
Pubmed

ATR couples FANCD2 monoubiquitination to the DNA-damage response.

ATR FANCD2

2.21e-052164215314022
Pubmed

Development of a PCR-SSOP approach capable of defining the natural killer cell inhibitory receptor (KIR) gene sequence repertoires.

KIR3DL1 KIR3DS1

2.21e-052164211098931
Pubmed

Complement receptor 3 deficiency influences lesion progression during Leishmania major infection in BALB/c mice.

ITGAM PRKDC

2.21e-052164219797068
Pubmed

Fancd2 functions in a double strand break repair pathway that is distinct from non-homologous end joining.

FANCD2 PRKDC

2.21e-052164216135554
Pubmed

Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.

KIR3DL1 KIR3DS1

2.21e-052164219411600
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

ATR CLASP1 HNRNPM YTHDC2 DCTN1 IQGAP1 EFTUD2 FANCD2 ARHGEF1 TPX2 MACF1 PRKDC

2.25e-055821641220467437
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

UIMC1 CLASP1 STAT2 PPP4R3B CYFIP1 ZNF516 MACF1 DDX20 CRYBG3 ATP1A1 DNMBP TRIM37

2.49e-055881641238580884
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

EPS15 ATP6V0A1 RPAP3 HNRNPM POR EXT2 TRIM24 DCTN1 DDX27 TMCC3 RRP1 EFTUD2 TXNL1 GUF1 EFNB1 SACS MRPS23 MACF1 CRYBG3 USP33

2.53e-0514871642033957083
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

UIMC1 ABL2 LARP1 CDCP1 DCTN1 MYOF SACS MACF1 PRKDC

3.06e-05332164937433992
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

HNRNPM LARP1 YTHDC2 ADARB1 DDX27 APOBEC3B RRP1 EFTUD2 SRRT NOM1 MRPS23 RBM5 MACF1 PRKDC

3.13e-058071641422681889
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

HNRNPM LARP1 DDX27 RRP1 IQGAP1 LGALS7 EFTUD2 SRRT LIG3 NOM1 RBM5 PRKDC

3.28e-056051641228977666
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

EPS15 ACACA HNRNPM LARP1 CPT2 DCTN1 GDI1 IQGAP1 EFTUD2 LIG3 CYFIP1 MRPS23 MACF1 AFDN DDX20 PRKDC ATP1A1

3.31e-0511491641735446349
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR3DL1 KIR3DL2 KIR3DS1

3.61e-0514164319875891
Pubmed

[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].

KIR3DL1 KIR3DL2 KIR3DS1

3.61e-0514164319489269
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR3DL1 KIR3DL2 KIR3DS1

3.61e-0514164315896204
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH7 DNAH8

3.61e-051416439373155
Pubmed

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

KIR3DL1 KIR3DL2 KIR3DS1

3.61e-0514164318945962
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR3DL1 KIR3DL2 KIR3DS1

4.49e-0515164320082646
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR3DL1 KIR3DL2 KIR3DS1

4.49e-0515164320356536
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR3DL1 KIR3DL2 KIR3DS1

4.49e-0515164319926642
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR3DL1 KIR3DL2 KIR3DS1

4.49e-0515164320643584
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR3DL1 KIR3DL2 KIR3DS1

4.49e-0515164319326408
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

HNRNPM TRRAP IQGAP1 LGALS7 EFTUD2 MYOF RBM5 PRKDC

4.82e-05272164831010829
Pubmed

Repression of rRNA transcription by PARIS contributes to Parkinson's disease.

ACACA HNRNPM DDX27 EFTUD2 CYFIP1 MRPS23 PRKDC ATP1A1

4.82e-05272164825315684
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

ACACA ATR LARP1 IQGAP1 MYOF PRKDC ATP1A1

5.18e-05202164733005030
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

MYH2 LARP1 OAS3 YTHDC2 ARHGAP11A DDX27 RRP1 IQGAP1 EFTUD2 FANCD2 LIG3 MYOF EIF2B1 NOM1 OASL MRPS23 DDX20 PRKDC ATP1A1

5.29e-0514401641930833792
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

UIMC1 EPS15 ACACA RPAP3 HNRNPM LARP1 TRIM24 LGALS7 LIG3 SENP5

5.31e-054441641034795231
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR3DL1 KIR3DL2 KIR3DS1

5.51e-0516164319897003
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR3DL1 KIR3DL2 KIR3DS1

5.51e-0516164319000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR3DL1 KIR3DL2 KIR3DS1

5.51e-0516164320670355
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR3DL1 KIR3DL2 KIR3DS1

5.51e-0516164318668235
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR3DL1 KIR3DL2 KIR3DS1

5.51e-0516164319309280
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR3DL1 KIR3DL2 KIR3DS1

5.51e-0516164319527230
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR3DL1 KIR3DL2 KIR3DS1

5.51e-0516164320652381
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR3DL1 KIR3DL2 KIR3DS1

5.51e-0516164319279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR3DL1 KIR3DL2 KIR3DS1

5.51e-0516164317868255
GeneFamilyEF-hand domain containing

EPS15 EFCAB6 CIB3 TBC1D8B DNAH7 NECAB1 MACF1 RHOT1

5.79e-052191108863
GeneFamilyDyneins, axonemal

DNAH10 DNAH7 DNAH8

1.40e-04171103536
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR3DL1 KIR3DL2 KIR3DS1

1.67e-04181103620
GeneFamilyEphrins

EFNA4 EFNB1

1.00e-0381102546
GeneFamilyBone morphogenetic proteins|Astacins

BMP1 BMP10

1.95e-03111102455
GeneFamilyDEAD-box helicases

DDX12P DDX27 DDX20

2.12e-03421103499
GeneFamilyCD molecules|Type II classical cadherins

CDH19 CDH12

2.74e-031311021186
GeneFamilyMyotubularins|Phosphoinositide phosphatases

SBF2 MTMR9

3.66e-03151102903
CoexpressionGSE15330_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_VS_PRO_BCELL_UP

UIMC1 ATP6V0A1 RIBC2 POR GABARAP ADARB1 IQGAP1 MYOF SACS DNMBP IL7R KIF22

5.32e-0920016412M7053
CoexpressionHOWARD_MONOCYTE_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

UBE2L6 OAS3 DTX3L CDCP1 ADARB1 APOBEC3B GFRA2 STAT2 MYOF KCNJ15 OASL

2.47e-0723116411M40995
CoexpressionGSE9946_IMMATURE_VS_LISTERIA_INF_MATURE_DC_DN

UIMC1 TRIM24 MYOF CYFIP1 GYS2 AOC3 PDE5A CDH12

2.00e-061331648M420
CoexpressionGSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_DN

UBE2L6 LARP1 OAS3 DTX3L STAT2 MYOF GTF2H1 EFNA4 OASL

4.80e-061991649M3286
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

EPS15 ATR CLASP1 SEMA5A ARHGAP11A TRIM24 TRRAP ADARB1 MYOF SACS MKLN1 MACF1 CRYBG3 DNMBP MNAT1 TRIM37 IL7R

2.81e-0585616417M4500
CoexpressionGSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN

UBE2L6 TRIM31 OAS3 DTX3L STAT2 ERRFI1 OASL MKLN1

3.42e-051961648M4267
CoexpressionGSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_DN

UBE2L6 OAS3 DTX3L STAT2 MYOF GTF2H1 FIG4 OASL

3.81e-051991648M3311
CoexpressionGSE19888_ADENOSINE_A3R_INH_VS_ACT_WITH_INHIBITOR_PRETREATMENT_IN_MAST_CELL_UP

UBE2L6 OAS3 DTX3L APOBEC3B STAT2 OTP NECAB1 OASL

3.95e-052001648M7322
CoexpressionGSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN

UIMC1 EPS15 TENT5C CYFIP1 ARHGEF1 SBF2 ATP1A1 IL7R

3.95e-052001648M8506
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

UBE2L6 OAS3 DTX3L STAT2 HELB NAA25 OASL IL7R

4.78e-0718816386f8946d4710f6e32c937213f99b790b098b8819c
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FLT4 UBE2L6 WWC3 OAS3 EFNB1 AFDN IL7R PARP15

7.64e-07200163889821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

L1TD1 CDH19 GFRA2 GUCY2F GYS2 ANKAR KCNJ15

1.04e-0614416371d05aa08603cba28c0c6511767e434c1f592a3aa
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

L1TD1 CDH19 GFRA2 GUCY2F GYS2 ANKAR KCNJ15

1.04e-061441637d3f6f5da56794367ee3776bfd3a9dcf893efe0f0
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

UBE2L6 OAS3 DTX3L STAT2 HELB NAA25 OASL

4.43e-061791637af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA1 DNAH7 KCNJ15 MKLN1 PHYHIPL UPP2 CACNA2D3

5.70e-061861637f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EFCAB6 LAMA1 DNAH7 MKLN1 PHYHIPL UPP2 CACNA2D3

5.90e-061871637c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACC1 ABL2 POR OASL AOC3 GPNMB MMP19

6.33e-061891637a59025e82fabd9d60e2438dee85b2644478cc7c8
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 CDCP1 DNAH7 MYOF AFDN ATP1A1 CACNA2D3

7.26e-06193163742df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 CDCP1 DNAH7 MYOF AFDN ATP1A1 CACNA2D3

7.26e-061931637f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellCOVID-19-Myeloid-TRAM2|COVID-19 / Condition, Lineage and Cell class

MACC1 PXDC1 TRIM31 CDCP1 OASL AOC3 GPNMB

7.51e-061941637c5bdf2b58c10dcb09797ddaf46b2e6c80d10399f
ToppCellMild|World / Disease group and Cell class

UBE2L6 GABARAP OAS3 DTX3L HELB ARHGEF1 OASL

8.03e-0619616375e4ed4a5a437cfa002b92775992a791e27aa4c27
ToppCellMild-CD8+_T_activated|World / Disease group and Cell class

UBE2L6 OAS3 DTX3L STAT2 HELB ARHGEF1 OASL

8.03e-06196163779632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCellCV-Mild-1|CV / Virus stimulation, Condition and Cluster

UBE2L6 OAS3 DTX3L STAT2 HELB OASL IL7R

8.57e-0619816374b078714c49e7befb7b113d72485e712236d35fa
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ACACA CLASP1 ADGRB3 FOCAD LINGO1 SBF2 MKLN1

8.86e-06199163794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACACA WWC3 BMP1 NECAB1 KCNJ15 KCNQ3 ATP1A1

8.86e-0619916378587bd98de7767a575088afbea07a1feb4516b9b
ToppCell18-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

ARHGAP11A APOBEC3B OLFML3 GFRA2 TPX2 AOC3 MACF1

8.86e-0619916377ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCellmild-CD163+_Monocytes_(Sample_ID1_d7)|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

UBE2L6 OAS3 DTX3L APOBEC3B STAT2 MYOF OASL

9.15e-06200163782126e25bfd8fba78dc1348fa5ad6a576289a139
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tnc|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MACC1 CYP26B1 DNAH10 GFRA2 BMP1 LINGO1

2.22e-0515416360066b2b8cfc74603e97f271ef5efc7ec512110dc
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

UIMC1 ATP6V0A1 TRRAP EFNB1 IL7R SENP5

2.31e-051551636a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ITGAM RRP1 FOXB1 GPNMB IL7R LGI1

2.76e-0516016366d941e584360975e1fdbb2fc67af8e31f18759d8
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MACC1 DNAH10 SEMA5A EFNA4 AOC3 GPNMB

3.51e-051671636cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SLC26A2 ITGAM TMCC3 BMP1 DNMBP PARP15

3.63e-05168163694cded2e953c0970bf2f3dbe0ce46bd77a5ed8c7
ToppCell10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages|bone_marrow / Manually curated celltypes from each tissue

PXDC1 CDCP1 OLFML3 GFRA2 GPNMB MMP19

4.41e-0517416360746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Il33_(Il33)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

ABL2 LAMA1 OLFML3 DNMBP MMP19

4.63e-051071635d446ffbe93cd49669f1cf91411aae07cc15d9e2a
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Il33_(Il33)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ABL2 LAMA1 OLFML3 DNMBP MMP19

4.63e-0510716355c9e745d0b08a4aa1f3a93f9cc094fac57061a30
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

UBE2L6 OAS3 STAT2 HELB OASL IL7R

4.85e-051771636a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellfacs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP11A DSN1 LINGO1 TPX2 DNAH8 KIF22

4.85e-051771636e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCellfacs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP11A DSN1 LINGO1 TPX2 DNAH8 KIF22

4.85e-0517716368a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYT7 IQGAP1 MYOF ATP1A1 UPP2 CACNA2D3

5.66e-051821636a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

UBE2L6 OAS3 DTX3L STAT2 NAA25 DNAH8

5.84e-051831636dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RPAP3 ADARB1 OLFML3 GUF1 FASTKD3 MTMR9

5.84e-051831636dc9602bed3136db91faeffef177006246dc92743
ToppCellfacs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPY19L2 SEMA5A PKDREJ ERRFI1 AOC3 SMARCD3

5.84e-051831636421265fa15d5a028cb567bb0904e670473ef102b
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

UIMC1 ATP6V0A1 DTX3L TRRAP EFNB1 SENP5

5.84e-051831636807d64deaf4e50dccf6f831f88578a6d903c1421
ToppCellfacs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPY19L2 SEMA5A PKDREJ ERRFI1 AOC3 SMARCD3

5.84e-0518316368d45dff06a199b1369576657f7f9dc0249c5f841
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 CDCP1 BMP1 KCNJ15 ERRFI1 CACNA2D3

5.84e-051831636e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellPBMC-Mild-cDC_9|Mild / Compartment, Disease Groups and Clusters

OAS3 DTX3L CDCP1 APOBEC3B GFRA2 MYOF

6.02e-0518416362e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCellControl-CD8+_T_activated|Control / Disease group and Cell class

OAS3 EXT2 DTX3L STAT2 HELB OASL

6.02e-051841636b86cc48b744b3206880ec1373fe6068e14bf9680
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC26A2 TDRD1 OLFML3 CYFIP1 EFNB1 GPNMB

6.20e-051851636ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC26A2 TDRD1 OLFML3 CYFIP1 EFNB1 GPNMB

6.20e-0518516363beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC26A2 TDRD1 OLFML3 CYFIP1 EFNB1 GPNMB

6.20e-05185163642939b294ea3e871274d8b73124c850dc1904fd2
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC26A2 TDRD1 OLFML3 CYFIP1 EFNB1 GPNMB

6.20e-0518516367a3612520ae4f0cd61480eadba31eecce001419d
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC26A2 TDRD1 OLFML3 CYFIP1 EFNB1 GPNMB

6.20e-051851636ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC26A2 TDRD1 OLFML3 CYFIP1 EFNB1 GPNMB

6.20e-0518516369aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP26B1 SYT7 ZNF516 SMARCD3 LRRD1 TRIM37

6.20e-051851636bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCellSevere_COVID-19-Myeloid-transitional_Macro|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

SLC26A2 TDRD1 OLFML3 CYFIP1 EFNB1 GPNMB

6.20e-051851636f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

UIMC1 ATP6V0A1 DTX3L TRRAP EFNB1 SENP5

6.39e-05186163676cbc3610aedf8c19c17ad5faf6ef5e8980b6af5
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

L1TD1 SEMA5A FRY LINGO1 ACAN AOC3

6.39e-0518616361e3ab663e4756975db6d802b2c6c054a94a79393
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP11A DSN1 FANCD2 TPX2 DNAH8 KIF22

6.39e-0518616369feef5936985e936b3d88f9d1bb012abb6468570
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYT7 GFRA2 NDST3 LINGO1 NECAB1 CACNA2D3

6.39e-051861636bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCellfacs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP11A DSN1 FANCD2 TPX2 DNAH8 KIF22

6.39e-05186163689f5b06bc56674af304912d481ac697c7c870904
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WWC3 OAS3 DTX3L EFNB1 IL7R PARP15

6.58e-051871636f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCellMesenchymal_cells-Ng2+_MSCs|Mesenchymal_cells / Lineage and Cell class

SEMA5A ADARB1 OLFML3 BMP1 EFNB1 KCNJ15

6.58e-051871636e899b906409f3fad69cb3d3c6432c3fd862ae3c1
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACC1 ABL2 OASL GPNMB MMP19 IL7R

6.58e-0518716367b24a324335c30c4b37795c43611b297274c804b
ToppCell15-Distal-Mesenchymal-Pericyte|Distal / Age, Tissue, Lineage and Cell class

SEMA5A LINGO1 NECAB1 ACAN AOC3 KCNQ3

6.77e-0518816364963382e54aac06bf5047c7d725393db70667ee7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

ACACA INO80 NECAB1 KCNJ15 KCNQ3 SMARCD3

6.77e-051881636ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellfacs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTF2A1L TRIM31 ARHGAP11A DSN1 TPX2 KIF22

6.98e-051891636bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCellfacs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTF2A1L TRIM31 ARHGAP11A DSN1 TPX2 KIF22

6.98e-05189163696f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYT7 FOCAD NDST3 LINGO1 NECAB1 CACNA2D3

6.98e-051891636c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 SEMA5A KCNJ15 ERRFI1 KCNQ3 PHYHIPL

6.98e-0518916363b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac|lymph-node_spleen / Manually curated celltypes from each tissue

CDCP1 GFRA2 NDST3 MYOF GPNMB MMP19

6.98e-051891636aac79c41ce7acba722c45c016b2c6997fb772a96
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP26B1 PXDC1 EFNB1 GRTP1 DNAH8 TRIM37

6.98e-05189163616e019fd6e2376110b767739754389891f391669
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYT7 NDST3 LINGO1 NECAB1 CDH12 CACNA2D3

7.18e-051901636d594da827e3c16644952b9589cc12b947ce36279
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

UBE2L6 TRIM31 OAS3 DTX3L STAT2 OASL

7.39e-0519116362da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADARB1 FRY LINGO1 ACAN AOC3 GPNMB

7.39e-051911636239c1e68eb1cbe3e137a99fbd6eeb8d64c919ffd
ToppCellfacs-SCAT-Fat-3m-Endothelial-endothelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 TMCC3 FRY EFNB1 AFDN TRIM37

7.39e-0519116366b9bbf4a63d4e9a8075bb06c2aa644fcf4ee88b8
ToppCellfacs-SCAT-Fat-3m-Endothelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 TMCC3 FRY EFNB1 AFDN TRIM37

7.39e-051911636a0018f88f7132477cc467ee15db029a585290595
ToppCellwk_20-22-Hematologic_Lymphocytic-NK-Cycling_NK|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ARHGAP11A DSN1 APOBEC3B FANCD2 TPX2 KIF22

7.39e-0519116365d4fed25bd318472a17228b12ade4c331865bda5
ToppCellfacs-SCAT-Fat-3m-Endothelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 TMCC3 FRY EFNB1 AFDN TRIM37

7.39e-05191163690f0c193dce267a4f1a9b2501f636dafd0a34cf7
ToppCellNon-neuronal-Dividing-Radial_Glia-Low_Quality-16|World / Primary Cells by Cluster

NBEAL1 HNRNPM GABARAP ARHGAP11A TPX2 KIF22

7.61e-0519216360d6413df15dfecdffc777fb02df3aaf0c30540b1
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACACA BMP1 NECAB1 KCNJ15 ERRFI1 KCNQ3

7.61e-051921636cc9911e182a289779a2612bc213daae5607689e7
ToppCellNon-neuronal-Dividing-Radial_Glia-Low_Quality|World / Primary Cells by Cluster

NBEAL1 HNRNPM GABARAP ARHGAP11A TPX2 KIF22

7.61e-0519216365fa5b2f250ec5ad5a232c022266f0cd01ff4a753
ToppCellMesenchymal_cells-Ng2+_MSCs|World / Lineage and Cell class

SEMA5A ADARB1 OLFML3 BMP1 EFNB1 KCNJ15

7.61e-0519216360703b8ec6960ff975ee5a2737054db67cab016b5
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SBF2 IL7R

7.79e-0541632776052094988928af65897bd748dff8a67722870
ToppCellfacs-Aorta-Heart-18m-Endothelial-aortic_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP26B1 PXDC1 SYT7 TMCC3 EFNB1 AFDN

7.83e-0519316367b7fecd332d3c99b8810bd7e14ab33aab46f2ffd
ToppCellfacs-Aorta-Heart-18m-Endothelial|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP26B1 PXDC1 SYT7 TMCC3 EFNB1 AFDN

7.83e-0519316367170cbaef0ba1b65cab89c5d4ce525e6c04e4418
ToppCellfacs-Aorta-Heart-18m-Endothelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP26B1 PXDC1 SYT7 TMCC3 EFNB1 AFDN

7.83e-051931636348a89bbf5fe7f7c875300c9ec3cb245c37e1308
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

ACACA WWC3 BMP1 NECAB1 KCNJ15 KCNQ3

7.83e-051931636738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 DNAH7 MYOF AFDN ATP1A1 CACNA2D3

8.06e-051941636e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 LAMA1 DNAH7 KCNJ15 ATP1A1 CACNA2D3

8.06e-05194163693c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EFCAB6 DNAH10 RIBC2 TOGARAM2 DNAH7 C1orf141

8.06e-0519416361ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellcontrol-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

UBE2L6 OAS3 DTX3L STAT2 KCNJ15 OASL

8.06e-051941636267e213e8efe53aadfe553a2ca010a0e3b4b8939
ToppCellCOVID-19-Myeloid-TRAM2|Myeloid / Condition, Lineage and Cell class

MACC1 TRIM31 CDCP1 OASL AOC3 GPNMB

8.06e-0519416364060a60c0271e7397b07993a1ef47b3291bba6e3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EFCAB6 DNAH10 RIBC2 TOGARAM2 DNAH7 C1orf141

8.06e-0519416364a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

UBE2L6 OAS3 DTX3L STAT2 OASL GPNMB

8.06e-051941636e36d1fd141bdcbd9ed66a33de6cdfde77189a0c1
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

ICOSLG UBE2L6 OAS3 DTX3L STAT2 OASL

8.06e-051941636d1366b169d14011194e61d16b6b0953349febc78
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYT7 FOCAD LINGO1 NECAB1 CDH12 CACNA2D3

8.29e-0519516362e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

UBE2L6 OAS3 DTX3L STAT2 NAA25 OASL

8.29e-051951636b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellMild-CD4+_T_activated|World / Disease group and Cell class

UBE2L6 OAS3 DTX3L STAT2 HELB OASL

8.52e-051961636417b4fc2e4388f34c410576131b02936f93e46b6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABL2 CDCP1 ITGAM KCNJ15 MMP19 IL7R

8.52e-051961636a44a648bf209ce037bfc7b3adfcb220aab60728c
ToppCellCV-Moderate-1|Moderate / Virus stimulation, Condition and Cluster

UBE2L6 OAS3 DTX3L STAT2 OASL KIR3DL1

8.52e-051961636b50cfcd87c5b67806450cb8b3c6860ab97f6d3b1
ToppCellEnterocyte-C_05|Enterocyte / shred on cell type and cluster

SLC26A2 TRIM31 OAS3 DTX3L MYOF OASL

8.52e-051961636c307e5a70186567c62da938caa21749dc0e929d0
ToppCelldroplet-Heart-HEART-1m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA5A OLFML3 BMP1 ERRFI1 AOC3 SMARCD3

8.52e-0519616361eb14182ef26e6141f510d397b00bf8a12efda3e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 LAMA1 DNAH7 KCNJ15 PHYHIPL CACNA2D3

8.52e-0519616366ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGRB3 ADARB1 OLFML3 AOC3 MACF1 PDE5A

8.52e-051961636cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_9|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CDCP1 APOBEC3B GFRA2 MYOF AFG1L

8.64e-0512216357dabf8b4c34a3714f45c3a99c1aa159e2d0b7e9c
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_9|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CDCP1 APOBEC3B GFRA2 MYOF AFG1L

8.64e-051221635489a01c71882be5a6d71a19d06574698988c20f6
ToppCellControl-Myeloid-TRAM3|Control / Disease group,lineage and cell class （2021.01.30）

UBE2L6 OAS3 DTX3L STAT2 MYOF OASL

8.76e-051971636733ff40039d67e561c2ded7c9bd0b4353101741e
ToppCellCV-Moderate-1|CV / Virus stimulation, Condition and Cluster

UBE2L6 OAS3 DTX3L STAT2 OASL KIR3DL1

8.76e-051971636e3d00d850b4d191f9592ef993c0eaadfe5710b5f
ToppCellBAL-Control-Myeloid-TRAM-TRAM3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UBE2L6 OAS3 DTX3L STAT2 MYOF OASL

8.76e-0519716360f1c4a328968b32874e6ebb0803e665adcbbc450
DrugFlufenamic acid [530-78-9]; Down 200; 14.2uM; HL60; HG-U133A

ASNSD1 EPS15 LARP1 CPT2 DCTN1 DDX27 LIG3 OASL MACF1

1.19e-0519516391420_DN
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; PC3; HT_HG-U133A

CCDC134 PXDC1 TENT5C STAT2 CRB1 BMP10 AFM AFDN IL7R

1.23e-0519616394443_UP
DrugEdrophonium chloride [116-38-1]; Up 200; 19.8uM; PC3; HT_HG-U133A

ICOSLG ABL2 ADARB1 BMP1 ZSCAN32 EFNB1 KCNJ15 AFDN PDE5A

1.23e-0519616396655_UP
DrugLorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A

MYH2 ABL2 TENT5C DNAH7 CRB1 ARHGEF1 AFDN GPNMB MMP19

1.34e-0519816395254_UP
DrugDecamethonium bromide [541-22-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A

ABL2 YTHDC2 BMP1 SRRT ZSCAN32 MYOF ZNF516 OASL RHOT1

1.34e-0519816397353_UP
Drugvinblastine sulfate; Up 200; 0.1uM; MCF7; HT_HG-U133A

SLC26A2 PXDC1 TENT5C ARHGAP11A TRRAP ADARB1 MYOF ARHGEF1 SMARCD3

1.34e-0519816397517_UP
DiseaseSquamous cell carcinoma of lung

ATR TRIM24 GUCY2F PRKDC

2.86e-05321634C0149782
Diseaseendometrial cancer (implicated_via_orthology)

ATR ERRFI1

8.31e-0481632DOID:1380 (implicated_via_orthology)
DiseaseDisproportionate short stature

SLC26A2 EXT2 ACAN KIF22

8.88e-04771634C0878659
DiseaseMalignant neoplasm of breast

RIBC2 PXDC1 DTX3L ARHGAP11A PKDREJ APOBEC3B SGK3 BMP1 NAA25 GUCY2F KCNJ15 MRPS23 MACF1 GPNMB FASTKD3

9.42e-04107416315C0006142
Diseaseosteoarthritis, hand

MYH2 CYP26B1 DNAH8

1.12e-03371633EFO_1000789
Diseasemotor neuron disease (implicated_via_orthology)

DCTN1 RHOT1

1.93e-03121632DOID:231 (implicated_via_orthology)
Diseaseresponse to angiotensin-converting enzyme inhibitor, Cough

CYP26B1 CLASP1 GYS2

2.11e-03461633EFO_0005325, HP_0012735
DiseaseCharcot-Marie-Tooth disease type 4

FIG4 SBF2

2.27e-03131632cv:C4082197
DiseasePneumoconiosis

ATR ACAN

2.64e-03141632C0032273
DiseaseBagassosis

ATR ACAN

2.64e-03141632C0004681
DiseaseInfluenza

UBE2L6 OAS3 OASL

3.00e-03521633C0021400
DiseaseStevens-Johnson syndrome, toxic epidermal necrolysis, response to anticonvulsant

DDX12P GFRA2

3.46e-03161632EFO_0004276, EFO_0004775, GO_0036277
DiseaseAmyotrophic lateral sclerosis

DCTN1 FIG4

3.91e-03171632cv:C0002736
DiseaseBipolar Disorder

ITGAM ADARB1 NDST3 SRRT KCNQ3 ATP1A1 DNAH8 AFG1L

5.18e-034771638C0005586
DiseaseSevere Combined Immunodeficiency

PRKDC IL7R

5.40e-03201632C0085110

Protein segments in the cluster

PeptideGeneStartEntry
PEDFFCQQLQSGRKL

TDRD1

506

Q9BXT4
PENLTFKERQRLFSQ

AFDN

1786

P55196
RKDPRFCAFVQEAES

ARHGEF1

531

Q92888
SNFEKSNLRPFFIQT

C1orf141

91

Q5JVX7
FPSSAFLRAKEEQQD

DCTN1

1226

Q14203
GESDRQPKESFFQFL

CRYBG3

111

Q68DQ2
DTFTFNFNNDPLVLR

APOBEC3B

196

Q9UH17
CIPQTRNKFAFREAV

ABL2

1126

P42684
LNQKFQTLDRFRDIP

ADGRB3

1441

O60242
PRDIENFNSTQKFIE

AFM

26

P43652
FLNFNLSNCERKEER

CDCP1

266

Q9H5V8
RFRSPDDSCNQLTKF

GYS2

556

P54840
FAVNLIFPRCQKEDA

GPNMB

96

Q14956
KNFDTIFLRNIPQFT

AFG1L

366

Q8WV93
IRKVNNADDFPNLFR

ACACA

321

Q13085
CFEETFQAPRKENAN

AMER1

216

Q5JTC6
PEKLFQAERNFNAAQ

DNMBP

1286

Q6XZF7
SNKQDPLERQFERFN

DEDD

216

O75618
QELFSRIPFNQALVF

DDX20

301

Q9UHI6
AVNFFKEVDECSRPN

BMP1

541

P13497
KNRSADFNPDFVFTE

DDX27

76

Q96GQ7
APKTIRDAFCVFEQN

AOC3

421

Q16853
LRFFNEVFKDSTQTP

CPT2

381

P23786
KFRRFFQTACDVPEL

IQGAP1

1261

P46940
PSPKTFEEVQFFNRN

NDST3

626

O95803
LFVEPFNRKARQENL

NBEAL1

1741

Q6ZS30
QNDTAFVFPRLRDFT

OLFML3

176

Q9NRN5
QFRKVCNHPELFERQ

INO80

811

Q9ULG1
EEQESPVNCFRKLFV

INTS10

161

Q9NVR2
KNPLRALVFDSTFDQ

GUF1

251

Q8N442
LRAVPKVNRTFQADF

KIR3DL2

266

P43630
FNPRLDTSEVVFNSK

LGALS7

51

P47929
SRDASINPAFLKEFQ

ANKAR

1311

Q7Z5J8
KRADSFPFSVEQSNL

OVOS1

1146

Q6IE37
RTVLPFSQEFQRDKQ

CYFIP1

866

Q7L576
RFQQVPTDALANKLF

LARP1

741

Q6PKG0
TNNTRSPKLFVVFFD

PARP15

651

Q460N3
SFNDCFIKIPRRPDQ

FOXB2

66

Q5VYV0
NKFETFPRELCTLEN

LRRD1

566

A4D1F6
TPLRKSNFRVQLFED

MNAT1

51

P51948
SNFRVQLFEDPTVDK

MNAT1

56

P51948
FDAKNPFLAAVTTNR

POR

276

P16435
QILRQFPCSFEFNEN

MTMR9

406

Q96QG7
RNFKVEFALNCEFVP

SBF2

1326

Q86WG5
FTNENPLETRNIAFF

ATP1A1

231

P05023
FKDVNVFDPDRFSQA

CYP26B1

406

Q9NR63
VSFPFFRKEQLEAAS

KCNQ3

406

O43525
FSERLQDFDKSNPIV

FOLH1

646

Q04609
KACQIFVRNLPFDFT

HNRNPM

651

P52272
LPAVRKVNRTFQADF

KIR3DL1

266

P43629
ESFKFVRLFPLNQQD

EIF2B1

231

Q14232
DAELNFFQRICFNTP

RHOT1

206

Q8IXI2
NNFKPEDITEALRAF

MMP19

46

Q99542
FAARSKEVINRPFTN

KIF22

361

Q14807
EAQNRPFDAKTSVFV

MYH2

26

Q9UKX2
VKPFNRNDEQFLEAF

PDE5A

481

O76074
DIPQRLKRQFTVFNC

DNAH8

2581

Q96JB1
VQFSEKIQRFTPFSL

EFNA4

106

P52798
DFSQFEQIRKSPDCT

KCNJ15

326

Q99712
DRLPSFQQSCRNFVK

COG8

116

Q96MW5
RNFPEQVFQDLQRKS

MACF1

741

O94854
NRIKTLNQDEFASFP

LINGO1

81

Q96FE5
RAEDALFFFVNNVIP

GABARAP

71

O95166
RKNLNVSFNPESFLD

IL7R

291

P16871
TLQPQNRDAFFKTLA

PPP4R3B

346

Q5MIZ7
PFQFVRNSLAQLREK

DPY19L2

81

Q6NUT2
IVKLFSRIFNCNPDD

LIG3

326

P49916
EKALRSFVQFPNASE

ADARB1

136

P78563
CRAINDFQQSFQKPE

RIBC2

96

Q9H4K1
DFQQSFQKPETRREF

RIBC2

101

Q9H4K1
ENFKNSFQPVNSLRE

RBM5

556

P52756
TVRLPEFQFSSQNKE

MACF1

2041

Q9UPN3
PEKFTFQEAANECRR

ACAN

261

P16112
SFNDCFIKIPRRPDQ

FOXB1

66

Q99853
NFCPSFSELQRNFVK

OASL

186

Q15646
FSLRLFNVTPQDEQK

ICOSLG

96

O75144
NPFIFTLRNDKFIQA

OR9A1P

286

Q8NGU1
ENPLQFFRFELCVKD

PCDHB14

111

Q9Y5E9
SEIANVFDFPDLNRF

ATR

976

Q13535
RSFKNEDLFSQPVSF

BMP10

106

O95393
RESFASEFQKNTEPL

DTX3L

291

Q8TDB6
EKFLRDFTENPCLRN

GFRA2

336

O00451
TLNFREFQNLCEKRP

EFCAB6

796

Q5THR3
NKVFVDNFDRDPSLI

CACNA2D3

196

Q8IZS8
DKPNLQFDTDAVRLF

FIG4

516

Q92562
AEQRPTFDEIFNQFK

GUCY2F

796

P51841
IRTDLNRTFPDNVKF

GRTP1

111

Q5TC63
RSILNKFFNPELVEN

DNAH7

3656

Q8WXX0
SFQFSIQKLEPFLRD

DSN1

141

Q9H410
CNRPEQEIRFTIKFQ

EFNB1

101

P98172
QEIRFTIKFQEFSPN

EFNB1

106

P98172
RVVKCSANPIFNEDF

C2CD4D

276

B7Z1M9
VSNQPLEFTFQKRDL

DDX12P

686

Q92771
SVKDVVRFFNRNFPE

ABCA2

2291

Q9BZC7
NNISILKEDPFLFCR

MACC1

91

Q6ZN28
KEARFPFLDENVVSF

ASNSD1

546

Q9NWL6
KNVCFDDFFPISQVR

GJB7

61

Q6PEY0
EAAIKPNFTVRDFRN

CDH12

531

P55289
RKFLVFVANFDENDP

GDI1

141

P31150
DFSTLSKVNNEDPFR

EPS15

726

P42566
FENPNQFCKDIAERI

FRY

2156

Q5TBA9
IKRICDQVFSRFPDF

ERCC6L2

486

Q5T890
PEFLNISIQDSRLFF

CRB1

996

P82279
EKNNLRVASFNDPDF

DNAH10

3451

Q8IVF4
RVASFNDPDFLKQLE

DNAH10

3456

Q8IVF4
NKTRPFFDNLLQDEL

SACS

3021

Q9NZJ4
RIFGDNFDPDFIKQR

SGK3

76

Q96BR1
LFPEKSEDFRENIFQ

CDH19

626

Q9H159
RQFPKFDAELNISDN

HELB

671

Q8NG08
RKRFEFPNSLIQSQA

FOCAD

6

Q5VW36
FFENKNSDEINIPRL

FANCD2

161

Q9BXW9
FTPAQLNELERSFAK

OTP

111

Q5XKR4
DKFISEFLQPNRQFL

OAS3

756

Q9Y6K5
RFEIAAEKLFNPNTN

PHYHIPL

251

Q96FC7
DLFNPNFKSTCQRFV

MRPS23

86

Q9Y3D9
KRNLNPIFNESFAFD

SYT7

326

O43581
TDIAVDSFFKPRFEQ

UPP2

161

O95045
DSFFKPRFEQVILDN

UPP2

166

O95045
EKCFSERDFSPLQTQ

ARHGAP11A

666

Q6P4F7
IFPVTNKDFRDFVRE

SUMF2

66

Q8NBJ7
KVVLCRSEEFQFLNP

TRIM31

251

Q9BZY9
FQVRSPTFFQKSRDQ

TRIM37

401

O94972
FFERSPLDQVLKNDN

PXDC1

126

Q5TGL8
NLRKFCRDIQPFSQD

STAT2

86

P52630
PVFVFNKSREFANLI

TMCC3

196

Q9ULS5
DFLEAFKNIQPSSFR

SPATA5L1

436

Q9BVQ7
QVFDAFTPRLQDSNK

TOGARAM2

806

Q6ZUX3
QRTQLFDTLVNFFPD

MKLN1

706

Q9UL63
FPEQQRFNSTLRLKE

PKDREJ

1886

Q9NTG1
NSIFQALCFQFEKEP

FASTKD3

156

Q14CZ7
IKSPQVQSFDFSRAF

LAMA1

3046

P25391
LPAVRKVNRTFQADF

KIR3DS1

266

Q14943
FQQIFDCPRLKFSEI

SMARCD3

311

Q6STE5
DKFRDLENLPATNFS

NOM1

731

Q5C9Z4
TADQNLKFIDPFCRI

RRP1

186

P56182
AQRLFTALFPFEKNC

ITGAM

756

P11215
SRSEFKNNFLNIDPI

ERRFI1

36

Q9UJM3
CSRFFIDFPDILEQQ

TENT5C

271

Q5VWP2
RAKNAVDFSQLTFDP

SEMA5A

51

Q13591
EVAFFNNFLTDAKRP

SRRT

746

Q9BXP5
SNFQNPFKIDRTEFI

CCDC134

176

Q9H6E4
KDNPFRQRIAQVFSE

CIB3

66

Q96Q77
KALDVTRDSFPFDQQ

CLASP1

961

Q7Z460
NNTKAFEVPARANFL

VIL1

526

P09327
PSDTKQFFLQCLNLR

ZNF516

376

Q92618
NLERFQVTKLCPFQE

GTF2H1

496

P32780
KPEDFVADFRLIFQN

TRIM24

961

O15164
DVFNEDFSNRKPFIN

SENP5

531

Q96HI0
DFSNRKPFINREITN

SENP5

536

Q96HI0
EQGFLRTPEQCRTKF

ZSCAN32

296

Q9NX65
SCKQLFDISLFRNPF

SLC16A4

286

O15374
LNRFFDNVTNKDSPL

TBC1D8B

706

Q0IIM8
STDFKQFETNDQCRP

SLC26A2

36

P50443
PANSFQLESDFRQLK

RPAP3

546

Q9H6T3
KATEDFFRNSIQSPL

GTF2A1L

51

Q9UNN4
QNPELFRKNAEEFTL

UBE2L6

131

O14933
FVRDFEQPFINKPDT

FLT4

131

P35916
VVRTAENKLSNRFFP

EXT2

511

Q93063
DPQTSREIFNFVLKA

PRKDC

241

P78527
QFRDLNPDVNVFQRK

ATP6V0A1

36

Q93050
FDSFRQSLPVFEKQE

YTHDC2

186

Q9H6S0
NEEAQIFRPLKFNTT

EFTUD2

571

Q15029
QPLIRAKFFEVFDNS

TRRAP

2451

Q9Y4A5
QPVFENVNVKSFDRC

UIMC1

206

Q96RL1
QVQTFREKIAFFTRP

WWC3

1066

Q9ULE0
FIRLNRAFQKEDSPA

USP33

831

Q8TEY7
CPFSFDSRDKERQLQ

TPX2

536

Q9ULW0
TPTFLFFRNKVRIDQ

TXNL1

76

O43396
SNVFNILRENDFEPK

L1TD1

261

Q5T7N2
FVKFQELNVQAPRSF

LGI1

511

O95970
TRIKRGNNPFFDELF

MYOF

231

Q9NZM1
EKIPEFIAFRNRLNN

NAA25

591

Q14CX7
KTFQRSNVDFLETPE

NECAB1

321

Q8N987