Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transporter activity	SLC25A38 BAK1 ATG9B SLC45A1 ATP1A1 ATP1A3 NDUFA12 TMCO1 SLC25A25 SLC22A17 ABCG5 SLC25A13 HTR3E	3.76e-07	1289	38	13	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC25A38 BAK1 SLC45A1 ATP1A1 ATP1A3 NDUFA12 TMCO1 SLC25A25 SLC22A17 ABCG5 SLC25A13 HTR3E	1.11e-06	1180	38	12	GO:0022857
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC45A1 ATP1A1 ATP1A3 NDUFA12 SLC25A25 ABCG5 SLC25A13	2.82e-05	477	38	7	GO:0022804
GeneOntologyMolecularFunction	steroid hormone binding	ATP1A1 ATP1A3	7.36e-05	7	38	2	GO:1990239
GeneOntologyMolecularFunction	P-type sodium transporter activity	ATP1A1 ATP1A3	1.57e-04	10	38	2	GO:0008554
GeneOntologyMolecularFunction	P-type sodium:potassium-exchanging transporter activity	ATP1A1 ATP1A3	1.57e-04	10	38	2	GO:0005391
GeneOntologyMolecularFunction	P-type potassium transmembrane transporter activity	ATP1A1 ATP1A3	1.92e-04	11	38	2	GO:0008556
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC45A1 ATP1A1 ATP1A3 NDUFA12 TMCO1 SLC25A13 HTR3E	2.24e-04	664	38	7	GO:0008324
GeneOntologyMolecularFunction	protein-folding chaperone binding	BAK1 GAK ATP1A1 ATP1A3	2.43e-04	161	38	4	GO:0051087
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC45A1 ATP1A1 ATP1A3 NDUFA12 SLC25A13	2.51e-04	301	38	5	GO:0022853
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ATP1A1 ATP1A3 NDUFA12 ABCG5	3.56e-04	178	38	4	GO:0015399
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC45A1 ATP1A1 ATP1A3 NDUFA12 TMCO1 SLC25A25 SLC25A13	4.99e-04	758	38	7	GO:0015318
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC45A1 ATP1A1 ATP1A3 NDUFA12 TMCO1 SLC25A13 HTR3E	6.52e-04	793	38	7	GO:0015075
GeneOntologyMolecularFunction	ankyrin binding	FLNC ATP1A1	8.70e-04	23	38	2	GO:0030506
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC45A1 ATP1A1 ATP1A3 NDUFA12 TMCO1 SLC25A13	1.10e-03	627	38	6	GO:0022890
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ATP1A1 ATP1A3 ABCG5	1.16e-03	109	38	3	GO:0042626
GeneOntologyMolecularFunction	cyclin binding	GAK KLHDC9	2.02e-03	35	38	2	GO:0030332
GeneOntologyMolecularFunction	P-type transmembrane transporter activity	ATP1A1 ATP1A3	2.13e-03	36	38	2	GO:0140358
GeneOntologyMolecularFunction	P-type ion transporter activity	ATP1A1 ATP1A3	2.13e-03	36	38	2	GO:0015662
GeneOntologyMolecularFunction	neutral L-amino acid transmembrane transporter activity	SLC25A38 SLC25A13	2.76e-03	41	38	2	GO:0015175
GeneOntologyMolecularFunction	proton transmembrane transporter activity	SLC45A1 NDUFA12 SLC25A13	5.44e-03	188	38	3	GO:0015078
GeneOntologyMolecularFunction	ATPase-coupled monoatomic cation transmembrane transporter activity	ATP1A1 ATP1A3	6.21e-03	62	38	2	GO:0019829
GeneOntologyMolecularFunction	L-amino acid transmembrane transporter activity	SLC25A38 SLC25A13	8.07e-03	71	38	2	GO:0015179
GeneOntologyBiologicalProcess	establishment or maintenance of transmembrane electrochemical gradient	BAK1 ATP1A1 ATP1A3	9.42e-07	11	38	3	GO:0010248
GeneOntologyBiologicalProcess	response to glycoside	ATP1A1 ATP1A3	3.29e-05	5	38	2	GO:1903416
GeneOntologyCellularComponent	photoreceptor inner segment membrane	ATP1A1 ATP1A3	1.82e-05	4	37	2	GO:0060342
GeneOntologyCellularComponent	ATPase dependent transmembrane transport complex	ATP1A1 ATP1A3 ABCG5	1.26e-04	55	37	3	GO:0098533
GeneOntologyCellularComponent	sodium:potassium-exchanging ATPase complex	ATP1A1 ATP1A3	1.99e-04	12	37	2	GO:0005890
Domain	P-type_ATPase_IIC	ATP1A1 ATP1A3	5.70e-05	6	37	2	IPR005775
Domain	SOLCAR	SLC25A38 SLC25A25 SLC25A13	1.57e-04	53	37	3	PS50920
Domain	Mito_carr	SLC25A38 SLC25A25 SLC25A13	1.57e-04	53	37	3	PF00153
Domain	-	SLC25A38 SLC25A25 SLC25A13	1.57e-04	53	37	3	1.50.40.10
Domain	Mt_carrier_dom	SLC25A38 SLC25A25 SLC25A13	1.57e-04	53	37	3	IPR023395
Domain	Mitochondrial_sb/sol_carrier	SLC25A38 SLC25A25 SLC25A13	1.57e-04	53	37	3	IPR018108
Domain	Gal_Oxase/kelch_b-propeller	KLHDC7B KLHDC9 KLHL18	2.16e-04	59	37	3	IPR011043
Domain	-	ATP1A1 ATP1A3	4.50e-04	16	37	2	1.20.1110.10
Domain	ATPase_P-typ_TM_dom	ATP1A1 ATP1A3	4.50e-04	16	37	2	IPR023298
Domain	ATPase_P-typ_cation-transptr_C	ATP1A1 ATP1A3	5.10e-04	17	37	2	IPR006068
Domain	Cation_ATPase_C	ATP1A1 ATP1A3	5.10e-04	17	37	2	PF00689
Domain	Cation_ATPase_N	ATP1A1 ATP1A3	5.73e-04	18	37	2	PF00690
Domain	Cation_ATPase_N	ATP1A1 ATP1A3	5.73e-04	18	37	2	SM00831
Domain	ATPase_P-typ_cation-transptr_N	ATP1A1 ATP1A3	6.39e-04	19	37	2	IPR004014
Domain	Mit_carrier	SLC25A25 SLC25A13	1.82e-03	32	37	2	IPR002067
Domain	-	ATP1A1 ATP1A3	1.82e-03	32	37	2	2.70.150.10
Domain	-	ATP1A1 ATP1A3	1.82e-03	32	37	2	3.40.1110.10
Domain	ATPase_P-typ_cyto_domN	ATP1A1 ATP1A3	2.18e-03	35	37	2	IPR023299
Domain	ATPase_P-typ_P_site	ATP1A1 ATP1A3	2.31e-03	36	37	2	IPR018303
Domain	P_typ_ATPase	ATP1A1 ATP1A3	2.31e-03	36	37	2	IPR001757
Domain	ATPASE_E1_E2	ATP1A1 ATP1A3	2.31e-03	36	37	2	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP1A1 ATP1A3	2.43e-03	37	37	2	IPR008250
Domain	E1-E2_ATPase	ATP1A1 ATP1A3	2.43e-03	37	37	2	PF00122
Domain	-	KLHDC7B KLHDC9	4.07e-03	48	37	2	2.120.10.80
Domain	Sushi	SUSD2 VCAN	4.76e-03	52	37	2	PF00084
Domain	CCP	SUSD2 VCAN	5.12e-03	54	37	2	SM00032
Domain	Kelch-typ_b-propeller	KLHDC7B KLHDC9	5.31e-03	55	37	2	IPR015915
Domain	SUSHI	SUSD2 VCAN	5.50e-03	56	37	2	PS50923
Domain	Sushi_SCR_CCP_dom	SUSD2 VCAN	5.69e-03	57	37	2	IPR000436
Domain	Kelch	KLHDC7B KLHL18	5.89e-03	58	37	2	SM00612
Domain	Kelch_1	KLHDC7B KLHL18	8.47e-03	70	37	2	PF01344
Domain	Kelch_1	KLHDC7B KLHL18	8.47e-03	70	37	2	IPR006652
Domain	MFS	SLC45A1 SLC22A17	1.02e-02	77	37	2	IPR011701
Domain	MFS_1	SLC45A1 SLC22A17	1.02e-02	77	37	2	PF07690
Domain	HAD-like_dom	ATP1A1 ATP1A3	1.07e-02	79	37	2	IPR023214
Pubmed	Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas.	ATP1A1 ATP1A3	1.16e-06	2	38	2	21498719
Pubmed	Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.	ATP1A1 ATP1A3	1.16e-06	2	38	2	23761886
Pubmed	The family of human Na+,K+-ATPase genes. A partial nucleotide sequence related to the alpha-subunit.	ATP1A1 ATP1A3	1.16e-06	2	38	2	3030810
Pubmed	All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides.	ATP1A1 ATP1A3	1.16e-06	2	38	2	11546672
Pubmed	Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.	ATP1A1 ATP1A3	1.16e-06	2	38	2	24391932
Pubmed	Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression.	ATP1A1 ATP1A3	3.48e-06	3	38	2	8203495
Pubmed	Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.	ATP1A1 ATP1A3	3.48e-06	3	38	2	2822726
Pubmed	Na+/K+-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes.	ATP1A1 ATP1A3	3.48e-06	3	38	2	30819023
Pubmed	Na,K-ATPase and the role of alpha isoforms in behavior.	ATP1A1 ATP1A3	3.48e-06	3	38	2	18044013
Pubmed	Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.	ATP1A1 ATP1A3	3.48e-06	3	38	2	26988030
Pubmed	Glycoprotein nonmetastatic melanoma protein B (GPNMB) promotes the progression of brain glioblastoma via Na+/K+-ATPase.	ATP1A1 ATP1A3	3.48e-06	3	38	2	27836549
Pubmed	Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase.	ATP1A1 ATP1A3	3.48e-06	3	38	2	26373354
Pubmed	Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.	ATP1A1 ATP1A3	3.48e-06	3	38	2	26911348
Pubmed	Differential expression of Na+/K+-ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells.	ATP1A1 ATP1A3	3.48e-06	3	38	2	17947306
Pubmed	Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase.	ATP1A1 ATP1A3	3.48e-06	3	38	2	25994790
Pubmed	Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders.	ATP1A1 ATP1A3	3.48e-06	3	38	2	19058785
Pubmed	Knockout of sodium pump α3 subunit gene (Atp1a3-/-) results in perinatal seizure and defective respiratory rhythm generation.	ATP1A1 ATP1A3	3.48e-06	3	38	2	28465228
Pubmed	Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.	ATP1A1 ATP1A3	6.96e-06	4	38	2	21731499
Pubmed	The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.	ATP1A1 ATP1A3	6.96e-06	4	38	2	12458206
Pubmed	Na,K-ATPase expression in the mouse cochlea is not dependent on the mineralocorticoid receptor.	ATP1A1 ATP1A3	6.96e-06	4	38	2	11591489
Pubmed	Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.	ATP1A1 ATP1A3	6.96e-06	4	38	2	19751721
Pubmed	Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction.	ATP1A1 ATP1A3	6.96e-06	4	38	2	19376779
Pubmed	Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.	ATP1A1 ATP1A3	6.96e-06	4	38	2	21849490
Pubmed	Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes.	ATP1A1 ATP1A3	6.96e-06	4	38	2	17446412
Pubmed	Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice.	ATP1A1 ATP1A3	6.96e-06	4	38	2	17234593
Pubmed	Family of Na+,K+-ATPase genes. Intra-individual tissue-specific restriction fragment length polymorphism.	ATP1A1 ATP1A3	6.96e-06	4	38	2	2887455
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	LIG1 COPG2 NSUN5 ATP1A1 TMCO1 TRRAP SLC25A13	9.88e-06	704	38	7	29955894
Pubmed	Multiple genes encode the human Na+,K+-ATPase catalytic subunit.	ATP1A1 ATP1A3	1.16e-05	5	38	2	3035563
Pubmed	The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.	ATP1A1 ATP1A3	1.74e-05	6	38	2	3036582
Pubmed	Transport and pharmacological properties of nine different human Na, K-ATPase isozymes.	ATP1A1 ATP1A3	1.74e-05	6	38	2	10636900
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FLNC GAK ATP1A1 SRSF5 ATP1A3 NDUFA12 PLPPR4 RASAL1 VCAN	1.82e-05	1431	38	9	37142655
Pubmed	Differential involvement of Na(+),K(+)-ATPase isozymes in preimplantation development of the mouse.	ATP1A1 ATP1A3	2.43e-05	7	38	2	10837135
Pubmed	Expression and distribution of Na, K-ATPase isoforms in the human uterus.	ATP1A1 ATP1A3	2.43e-05	7	38	2	20065300
Pubmed	Molecular genetics of Na,K-ATPase.	ATP1A1 ATP1A3	2.43e-05	7	38	2	2158121
Pubmed	The mitochondrial transporter family SLC25: identification, properties and physiopathology.	SLC25A38 SLC25A25 SLC25A13	2.71e-05	53	38	3	23266187
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	MRPS5 COPG2 ATP1A1 SRSF5 ATP1A3 NDUFA12 SLC25A13 PSMB5	2.87e-05	1153	38	8	29845934
Pubmed	Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.	ATP1A1 SRSF5 TMCO1 SLC25A13 PSMB5	3.02e-05	333	38	5	36779763
Pubmed	Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit.	ATP1A1 ATP1A3	3.24e-05	8	38	2	19683723
Pubmed	Genes encoding alpha and beta subunits of Na,K-ATPase are located on three different chromosomes in the mouse.	ATP1A1 ATP1A3	3.24e-05	8	38	2	2885848
Pubmed	Enhanced inhibitory neurotransmission in the cerebellar cortex of Atp1a3-deficient heterozygous mice.	ATP1A1 ATP1A3	3.24e-05	8	38	2	23652595
Pubmed	The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm.	ATP1A1 ATP1A3	4.16e-05	9	38	2	15253893
Pubmed	Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.	FLNC TRRAP	6.35e-05	11	38	2	24349473
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	COPG2 FLNC ATP1A1 SRSF5 TRRAP SLC25A13	7.09e-05	653	38	6	22586326
Pubmed	Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach.	ATP1A1 ATP1A3 SLC25A13	7.10e-05	73	38	3	23464991
Pubmed	Retinal pigment epithelial integrity is compromised in the developing albino mouse retina.	ATP1A1 ATP1A3	7.62e-05	12	38	2	27097562
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	COPG2 TRRAP SLC25A13 PSMB5	8.27e-05	211	38	4	17314511
Pubmed	Chromosomal assignments of 17 structural genes and 11 related DNA fragments in rats (Rattus norvegicus) by Southern blot analysis of rat x mouse somatic cell hybrid clones.	ATP1A1 ATP1A3	1.05e-04	14	38	2	1572638
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	COPG2 GAK ATP1A1 TMCO1 SLC25A13	1.24e-04	449	38	5	31732153
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	MRPS5 COPG2 GAK ATP1A1 SRSF5 APRT SLC25A13 PSMB5	1.36e-04	1440	38	8	30833792
Pubmed	PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes.	ATP1A1 ATP1A3	1.56e-04	17	38	2	36230906
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	MRPS5 ATP1A1 NDUFA12 HIBCH TMCO1 SLC25A25 SLC25A13 PSMB5	1.77e-04	1496	38	8	32877691
Pubmed	RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks.	ATP1A1 ATP1A3	1.96e-04	19	38	2	20861386
Pubmed	Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.	SLC25A38 BAK1 MRPS5 NDUFA12 HIBCH SLC25A25 SLC25A13	2.02e-04	1136	38	7	34800366
Pubmed	Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol.	ATP1A1 ATP1A3	2.18e-04	20	38	2	15648052
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	COPG2 FLNC TMCO1 SLC22A17 SLC25A13 PSMB5	2.85e-04	844	38	6	25963833
Pubmed	Proteomic analysis of the palmitoyl protein thioesterase 1 interactome in SH-SY5Y human neuroblastoma cells.	ATP1A1 SLC25A13	3.16e-04	24	38	2	25865307
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	FLNC ATP1A1 SRSF5 SLC25A13 PSMB5	3.38e-04	558	38	5	27591049
Pubmed	Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy.	ATP1A1 SRSF5	3.43e-04	25	38	2	34747980
Pubmed	Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors.	COPG2 ATP1A1 SLC25A13	3.49e-04	125	38	3	36030824
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	COPG2 ATP1A1 SRSF5 ATP1A3 TMCO1 SLC25A13	3.52e-04	878	38	6	37223481
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	COPG2 ATP1A1 SRSF5 ATP1A3 APRT SLC25A13 PSMB5	3.57e-04	1247	38	7	27684187
Pubmed	Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.	SPTLC3 ACER3	4.01e-04	27	38	2	23096701
Pubmed	Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.	NSUN5 ATP1A1 APRT SLC25A13	4.20e-04	323	38	4	24797263
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	BAK1 MRPS5 COPG2 APRT TRRAP SUSD2 PSMB5	4.25e-04	1284	38	7	17353931
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	ATP1A1 NDUFA12 HIBCH SLC25A13	4.61e-04	331	38	4	29199018
Pubmed	Biology, structure and mechanism of P-type ATPases.	ATP1A1 ATP1A3	4.63e-04	29	38	2	15071553
Pubmed	The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.	NSUN5 ATP1A1 NDUFA12 SLC25A13 PSMB5	4.86e-04	604	38	5	37616343
Pubmed	Chromosomal localization of human Na+, K+-ATPase alpha- and beta-subunit genes.	ATP1A1 ATP1A3	4.96e-04	30	38	2	2842249
Pubmed	Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry.	NDUFA12 HIBCH SLC25A25 SLC25A13	5.27e-04	343	38	4	28130547
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	ATP1A1 ATP1A3 PSMB5	5.27e-04	144	38	3	35681168
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	ATP1A1 SRSF5 TRRAP SLC25A13 RASAL1	5.51e-04	621	38	5	22794259
Pubmed	SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.	LIG1 TRRAP SLC25A13	5.94e-04	150	38	3	30154076
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	MRPS5 LIG1 FLNC NSUN5 ATP1A1 SLC25A13	6.60e-04	989	38	6	36424410
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	LIG1 COPG2 ATP1A1 SRSF5 ATP1A3	7.50e-04	665	38	5	30457570
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FLNC ATP1A1 ATP1A3 NDUFA12 TMCO1 PCDHGA7 SLC25A13	8.47e-04	1442	38	7	35575683
Pubmed	A mitochondrial protein compendium elucidates complex I disease biology.	BAK1 MRPS5 NDUFA12 HIBCH SLC25A25 SLC25A13	8.88e-04	1047	38	6	18614015
Pubmed	Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.	SRMS ATP1A1 SLC25A13 PSMB5	9.43e-04	401	38	4	25852190
Pubmed	Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues.	ATP1A1 ATP1A3	9.74e-04	42	38	2	15146195
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MRPS5 COPG2 NSUN5 NDUFA12 TMCO1 TRRAP SLC25A13	1.05e-03	1497	38	7	31527615
Cytoband	Ensembl 112 genes in cytogenetic band chr7q32	COPG2 FLNC	2.96e-03	97	38	2	chr7q32
GeneFamily	ATPase Na+/K+ transporting subunits	ATP1A1 ATP1A3	5.19e-05	7	29	2	1208
GeneFamily	Solute carriers	SLC25A38 SLC45A1 SLC25A25 SLC22A17 SLC25A13	3.74e-04	395	29	5	752
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SUSD2 VCAN	3.75e-03	57	29	2	1179
Drug	AC1NST54	BAK1 ATP1A1 ATP1A3	5.15e-06	21	37	3	CID005315525
Drug	thevetin A	ATP1A1 ATP1A3	2.56e-05	5	37	2	CID000441873
Drug	22,23-dihydrobufalin	ATP1A1 ATP1A3	2.56e-05	5	37	2	CID000195392
Drug	3-acetylstrophanthin	ATP1A1 ATP1A3	2.56e-05	5	37	2	CID003082282
Drug	ETH157	ATP1A1 ATP1A3	3.84e-05	6	37	2	CID000563154
Drug	dihydrodigitoxigenin	ATP1A1 ATP1A3	5.37e-05	7	37	2	CID000107549
Disease	familial hemiplegic migraine (implicated_via_orthology)	ATP1A1 ATP1A3	3.20e-05	7	37	2	DOID:0060178 (implicated_via_orthology)
Disease	nervous system disease (implicated_via_orthology)	ATP1A1 ATP1A3	1.00e-04	12	37	2	DOID:863 (implicated_via_orthology)
Disease	cups of coffee per day measurement	ATP1A1 ATP1A3	1.16e-03	40	37	2	EFO_0006782
Disease	abdominal adipose tissue measurement	ATP1A1 ATP1A3	2.03e-03	53	37	2	EFO_0803316

Protein segments in the cluster

Peptide	Gene	Start	Entry
LRGLGYTSLGIFLLG	ACER3	171	Q9NUN7
GGGLLGVRTLYRFEN	VCAN	316	P13611
FSFYLLLGFLLQGRG	HTR3E	11	A5X5Y0
GRVVALLGFGYRLAL	BAK1	126	Q16611
GRIDYIAGLDSRGFL	APRT	56	P07741
KLFLGRGLAGRFLDY	RASAL1	311	O95294
RGGDYRGFFLLSILL	PCDHGA7	6	Q9Y5G6
LGYFLALTGFRLKGR	HIBCH	191	Q6NVY1
YELLLGKGFRGGGGR	NSUN5	76	Q96P11
GHGGLRGYLRVFFRT	NDUFA12	16	Q9UI09
AYLELGGLGERVLGF	ATP1A1	541	P05023
VFGDFLGRERLGSFG	FLNC	2221	Q14315
YGGFLDILRGGTERL	GAK	371	O14976
GLLYAIGGYDGQLRL	KLHL18	336	O94889
GRLGRAGTFLGEVYV	ABCG5	101	Q9H222
YLAGIFRGGYDLLVR	COPG2	826	Q9UBF2
DLLLFRGPFSLFRGG	ATG9B	401	Q674R7
AYLELGGLGERVLGF	ATP1A3	531	P13637
LGGFLYRFDLLRGVG	KLHDC7B	491	Q96G42
LRGRFYLVGGLLAGG	KLHDC9	36	Q8NEP7
LGRGKRAGRYGGFLL	LIG1	766	P18858
GFGRALGGQLRVIYL	SLC45A1	291	Q9Y2W3
LNRGQIIGEGRYGFL	MRPS5	126	P82675
GRSYAVLLGIIFGGL	SUSD2	781	Q9UGT4
LLLGGGGVYGSRFRF	TMCO1	16	Q9UM00
LFLGYPADRFGRRGI	SLC22A17	116	Q8WUG5
GIGTLFGYLRDFLRN	SPTLC3	71	Q9NUV7
LEEGGGYIFARRLSG	SRMS	81	Q9H3Y6
GYGRIRDIDLKRGFG	SRSF5	26	Q13243
YGLRGFFQGGIPRAL	SLC25A38	266	Q96DW6
VLRYEGFFGLYRGLL	SLC25A13	381	Q9UJS0
GFFGLYRGLLPQLLG	SLC25A13	386	Q9UJS0
ILRTEGAFGLYRGLA	SLC25A25	426	Q6KCM7
GFLIGGGIALYLGLY	PLPPR4	311	Q7Z2D5
YAGEVLRFVGGIGLF	TSPAN13	161	O95857
FIRSGGRLGQALLLY	nan	81	Q7L0L9
RGFFGLGGRADLLDL	PSMB5	16	P28074
GRRLGGLDPGVLYAF	VSIG10L2	661	P0DP72
YFLLLRALFRSIGGG	TRRAP	756	Q9Y4A5
GFGGLVQLRRGERVY	LTB	206	Q06643