| GeneOntologyMolecularFunction | histone modifying activity | AURKA KAT6A NSD1 PKN1 DOT1L KDM4B | 1.40e-04 | 229 | 69 | 6 | GO:0140993 |
| Pubmed | Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice. | AURKA ABCF3 WIZ OTULIN PDCD6IP ARFGEF2 PSMC6 PLEC ARHGEF2 SHOC2 GOLGB1 | 3.15e-08 | 582 | 72 | 11 | 20467437 |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | WIZ KANK3 KAT6A NSD1 ARFGEF2 PEX6 ARHGAP17 TWNK TNK2 PKN1 PLEC ARHGEF2 DOT1L SBNO2 | 5.28e-08 | 1105 | 72 | 14 | 35748872 |
| Pubmed | Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. | AURKA ABCF3 CGB1 PDCD6IP MTHFD1 UGGT1 HPS1 NSD1 PLEC DOT1L COG5 GOLGB1 SBNO2 | 3.15e-07 | 1084 | 72 | 13 | 11544199 |
| Pubmed | The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei. | AURKA CYFIP1 WIZ MTHFD1 NSD1 PALM3 ETV6 PSMC6 TWNK ARHGEF2 TAF6 TADA3 GOLGB1 SLC3A2 | 2.03e-06 | 1497 | 72 | 14 | 31527615 |
| Pubmed | Functional proteomics mapping of a human signaling pathway. | PDCD6IP MCAM ARFGEF2 PEX6 HTATSF1 TWNK PLEC PLIN3 GOLGB1 | 3.65e-06 | 591 | 72 | 9 | 15231748 |
| Pubmed | Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells. | CYFIP1 ABCF3 OTULIN PDCD6IP DDX18 UGGT1 HTATSF1 PSMC6 CP COG5 PLIN3 GOLGB1 SLC3A2 | 4.13e-06 | 1367 | 72 | 13 | 32687490 |
| Pubmed | Chfr is required for tumor suppression and Aurora A regulation. | AURKA CHFR | 4.23e-06 | 2 | 72 | 2 | 15793587 |
| Pubmed | Defining the membrane proteome of NK cells. | ABCF3 PDCD6IP MTHFD1 DDX18 ARFGEF2 PSMC6 TNK2 MSH3 COG5 PLIN3 GOLGB1 SLC3A2 | 4.66e-06 | 1168 | 72 | 12 | 19946888 |
| Pubmed | Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones. | AURKA CYFIP1 ABCF3 PDCD6IP MTHFD1 DDX18 UGGT1 HTATSF1 PLEC ARHGEF2 PLIN3 GOLGB1 SLC3A2 | 6.00e-06 | 1415 | 72 | 13 | 28515276 |
| Pubmed | New nomenclature for chromatin-modifying enzymes. | KAT6A NSD1 DOT1L KDM4B | 6.14e-06 | 57 | 72 | 4 | 18022353 |
| Pubmed | An Interaction Landscape of Ubiquitin Signaling. | UBXN2B OTULIN PDCD6IP FBXL15 PSMC6 TNK2 PLEC ARHGEF2 | 6.96e-06 | 481 | 72 | 8 | 28190767 |
| Pubmed | The UBXN-2/p37/p47 adaptors of CDC-48/p97 regulate mitosis by limiting the centrosomal recruitment of Aurora A. | AURKA UBXN2B | 1.27e-05 | 3 | 72 | 2 | 23649807 |
| Pubmed | Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein-Aurora A pathway. | AURKA HECW1 | 1.27e-05 | 3 | 72 | 2 | 26880200 |
| Pubmed | Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death. | PDCD6IP TNFRSF1A | 1.27e-05 | 3 | 72 | 2 | 18936101 |
| Pubmed | OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer. | OTULIN TNFRSF1A | 1.27e-05 | 3 | 72 | 2 | 32231246 |
| Pubmed | The interaction of ETV6 (TEL) and TIP60 requires a functional histone acetyltransferase domain in TIP60. | KAT6A ETV6 | 2.53e-05 | 4 | 72 | 2 | 17980166 |
| Pubmed | Loss of CHFR in human mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpoint. | AURKA CHFR | 2.53e-05 | 4 | 72 | 2 | 18592005 |
| Pubmed | cAMP-dependent protein kinase A (PKA) signaling induces TNFR1 exosome-like vesicle release via anchoring of PKA regulatory subunit RIIbeta to BIG2. | ARFGEF2 TNFRSF1A | 2.53e-05 | 4 | 72 | 2 | 18625701 |
| Pubmed | LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression. | MTHFD1 DDX18 PSMC6 ALDH4A1 PLEC ARHGEF2 GOLGB1 SLC3A2 | 2.67e-05 | 580 | 72 | 8 | 35676659 |
| Pubmed | VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. | ARFGEF2 ARHGAP17 PLEC ARHGEF2 COG5 SLC3A2 | 3.02e-05 | 288 | 72 | 6 | 23383273 |
| Pubmed | Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB. | WIZ PDCD6IP MTHFD1 DDX18 MCAM ARFGEF2 PKN1 GOLGB1 SLC3A2 | 3.21e-05 | 777 | 72 | 9 | 35844135 |
| Pubmed | Analysis of the Tropism of SARS-CoV-2 Based on the Host Interactome of the Spike Protein. | UGGT1 PLEC SLC3A2 | 3.67e-05 | 31 | 72 | 3 | 37939376 |
| Pubmed | USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c. | PDCD6IP MTHFD1 DDX18 PLEC | 3.77e-05 | 90 | 72 | 4 | 35654790 |
| Pubmed | GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases. | AURKA ARHGEF2 | 4.21e-05 | 5 | 72 | 2 | 17488622 |
| Pubmed | Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis. | PDCD6IP MTHFD1 PCLO DDX18 UGGT1 CP PLEC PALS2 SLC3A2 | 4.30e-05 | 807 | 72 | 9 | 30575818 |
| Pubmed | LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy. | UGGT1 MROH7 ARFGEF2 PLEC ARHGEF2 | 6.42e-05 | 202 | 72 | 5 | 33005030 |
| Pubmed | CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly. | AURKA PDCD6IP MTHFD1 UGGT1 ARFGEF2 PSMC6 PLEC | 7.43e-05 | 494 | 72 | 7 | 26831064 |
| Pubmed | OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice. | OTULIN TNFRSF1A | 8.82e-05 | 7 | 72 | 2 | 34625557 |
| Pubmed | Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN. | OTULIN TNFRSF1A | 8.82e-05 | 7 | 72 | 2 | 24461064 |
| Pubmed | PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα. | AURKA WIZ MTHFD1 ETV6 PSMC6 ARHGEF2 TAF6 TADA3 PLIN3 SLC3A2 | 8.91e-05 | 1103 | 72 | 10 | 34189442 |
| Pubmed | OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis. | OTULIN TNFRSF1A | 1.17e-04 | 8 | 72 | 2 | 32075762 |
| Pubmed | Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS. | OTULIN TNFRSF1A | 1.17e-04 | 8 | 72 | 2 | 35170849 |
| Pubmed | SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway. | CYFIP1 WIZ NSD1 DOT1L TAF6 PLIN3 SLC3A2 | 1.43e-04 | 549 | 72 | 7 | 38280479 |
| Pubmed | Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice. | NSD1 DOT1L KDM4B | 1.46e-04 | 49 | 72 | 3 | 34368113 |
| Pubmed | Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. | ABCF3 HPS1 ETV6 PSMC6 ST6GALNAC6 COG5 USH1C TADA3 | 1.49e-04 | 742 | 72 | 8 | 26871637 |
| Pubmed | OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin. | OTULIN TNFRSF1A | 1.51e-04 | 9 | 72 | 2 | 23746843 |
| Pubmed | E-cadherin interactome complexity and robustness resolved by quantitative proteomics. | ABCF3 PALM3 ELMOD3 PLEC PLIN3 GOLGB1 SLC3A2 | 1.70e-04 | 565 | 72 | 7 | 25468996 |
| Pubmed | In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker. | TTC24 PCLO UGGT1 TWNK PLEC ARHGEF2 POFUT2 PCDHGA8 PRX GOLGB1 SLC3A2 | 1.77e-04 | 1442 | 72 | 11 | 35575683 |
| Pubmed | OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity. | OTULIN TNFRSF1A | 1.88e-04 | 10 | 72 | 2 | 34625556 |
| Pubmed | Discovery of novel human transcript variants by analysis of intronic single-block EST with polyadenylation site. | PDCD6IP TNFRSF1A | 1.88e-04 | 10 | 72 | 2 | 19906316 |
| Pubmed | A high-throughput approach for measuring temporal changes in the interactome. | CYFIP1 ABCF3 PDCD6IP MTHFD1 UGGT1 ARFGEF2 HTATSF1 PSMC6 PLEC COG5 PLIN3 | 1.91e-04 | 1455 | 72 | 11 | 22863883 |
| Pubmed | Claudin-4 localization in epithelial ovarian cancer. | MCAM GOLGB1 SLC3A2 | 1.96e-04 | 54 | 72 | 3 | 36237976 |
| Pubmed | Confirmation of genomewide association signals in Chinese Han population reveals risk loci for ischemic stroke. | ASTN2 ITGB6 | 2.30e-04 | 11 | 72 | 2 | 19910543 |
| Pubmed | Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer. | AURKA PDCD6IP DDX18 ETV6 HTATSF1 MSH3 PLEC TAF6 TADA3 | 2.41e-04 | 1014 | 72 | 9 | 32416067 |
| Pubmed | Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover. | WIZ PCLO HTATSF1 PSMC6 ARHGAP17 GOLGB1 | 2.54e-04 | 425 | 72 | 6 | 24999758 |
| Pubmed | Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex. | MTHFD1 DDX18 HTATSF1 PSMC6 ARHGAP17 PLEC ARHGEF2 SLC3A2 | 2.67e-04 | 809 | 72 | 8 | 32129710 |
| Pubmed | SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD. | OTULIN TNFRSF1A | 2.75e-04 | 12 | 72 | 2 | 36640323 |
| Pubmed | LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes. | OTULIN TNFRSF1A | 2.75e-04 | 12 | 72 | 2 | 26670046 |
| Pubmed | Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation. | CYFIP1 PDCD6IP MCAM PLEC ARHGEF2 | 3.19e-04 | 285 | 72 | 5 | 21423176 |
| Pubmed | Complementation analyses for 45 mutations encompassing the pink-eyed dilution (p) locus of the mouse. | CYFIP1 CGB1 | 3.25e-04 | 13 | 72 | 2 | 8601493 |
| Pubmed | The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation. | CYFIP1 PDCD6IP MTHFD1 DDX18 PSMC6 PLEC SLC3A2 | 3.55e-04 | 638 | 72 | 7 | 33239621 |
| Pubmed | Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2. | HECW1 TNK2 | 4.36e-04 | 15 | 72 | 2 | 19144635 |
| Pubmed | Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling. | OTULIN TNFRSF1A | 4.36e-04 | 15 | 72 | 2 | 24726327 |
| Pubmed | Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function. | CYFIP1 ABCF3 PDCD6IP MTHFD1 DDX18 PSMC6 MSH3 PLEC ARHGEF2 SLC3A2 | 4.59e-04 | 1353 | 72 | 10 | 29467282 |
| Pubmed | Chfr is linked to tumour metastasis through the downregulation of HDAC1. | AURKA CHFR | 4.98e-04 | 16 | 72 | 2 | 19182791 |
| Pubmed | A human MAP kinase interactome. | PDCD6IP ARHGAP17 TNK2 PLEC COG5 GOLGB1 | 5.18e-04 | 486 | 72 | 6 | 20936779 |
| Pubmed | TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex. | PDCD6IP MTHFD1 GOLGB1 SLC3A2 | 5.31e-04 | 179 | 72 | 4 | 36261009 |
| Pubmed | Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development. | PLEC GOLGB1 SLC3A2 | 5.37e-04 | 76 | 72 | 3 | 27542412 |
| Pubmed | Histone-like TAFs within the PCAF histone acetylase complex. | TAF6 TADA3 | 5.63e-04 | 17 | 72 | 2 | 9674425 |
| Pubmed | Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones. | DNHD1 DOT1L | 5.63e-04 | 17 | 72 | 2 | 12693554 |
| Pubmed | CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1. | CYFIP1 MTHFD1 PSMC6 PLEC | 5.66e-04 | 182 | 72 | 4 | 31067453 |
| Pubmed | A High-Density Map for Navigating the Human Polycomb Complexome. | ZSWIM9 WIZ FBXL15 PSMC6 ARHGEF2 TADA3 | 5.70e-04 | 495 | 72 | 6 | 27705803 |
| Pubmed | Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development. | CYFIP1 PCLO MROH7 MSH3 PLEC SLC3A2 | 5.76e-04 | 496 | 72 | 6 | 31343991 |
| Pubmed | The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures. | NSD1 DOT1L | 6.33e-04 | 18 | 72 | 2 | 21030982 |
| Pubmed | The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4. | LIPA KAT6A NSD1 PLEC ARHGEF2 | 6.38e-04 | 332 | 72 | 5 | 37433992 |
| Pubmed | Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing. | CYFIP1 WIZ MTHFD1 HTATSF1 TAF6 GOLGB1 | 6.39e-04 | 506 | 72 | 6 | 30890647 |
| Pubmed | BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway. | AURKA CYFIP1 PDCD6IP MTHFD1 PLIN3 GOLGB1 SLC3A2 | 6.59e-04 | 708 | 72 | 7 | 39231216 |
| Pubmed | BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis. | DDX18 PSMC6 ALDH4A1 PLEC PLIN3 GOLGB1 SLC3A2 | 6.75e-04 | 711 | 72 | 7 | 33022573 |
| Pubmed | Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. | DNHD1 CYFIP1 PDCD6IP MTHFD1 PCLO DDX18 UGGT1 PSMC6 MSH3 SLC3A2 | 6.86e-04 | 1425 | 72 | 10 | 30948266 |
| Pubmed | Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families. | ABCF3 MCAM ARFGEF2 GOLGB1 SLC3A2 | 7.00e-04 | 339 | 72 | 5 | 37232246 |
| Pubmed | SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1. | HECW1 FBXL15 | 7.06e-04 | 19 | 72 | 2 | 21572392 |
| Pubmed | RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes. | CYFIP1 PDCD6IP MTHFD1 PSMC6 SLC3A2 | 7.48e-04 | 344 | 72 | 5 | 36282215 |
| Pubmed | A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation. | ABCF3 WIZ DDX18 PSMC6 PLEC TADA3 PLIN3 | 7.51e-04 | 724 | 72 | 7 | 36232890 |
| Pubmed | UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation. | TAF6 TADA3 | 7.84e-04 | 20 | 72 | 2 | 11406595 |
| Pubmed | Function of TAF(II)-containing complex without TBP in transcription by RNA polymerase II. | TAF6 TADA3 | 7.84e-04 | 20 | 72 | 2 | 9603525 |
| Pubmed | Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction. | TAF6 TADA3 | 7.84e-04 | 20 | 72 | 2 | 10373431 |
| Pubmed | Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers. | AURKA LIPA HECW1 MTHFD1 KAT6A NSD1 DGKH | 7.88e-04 | 730 | 72 | 7 | 34857952 |
| Pubmed | A Large-scale genetic association study of esophageal adenocarcinoma risk. | AURKA MTHFD1 ALDH4A1 MSH3 TNFRSF1A | 8.19e-04 | 351 | 72 | 5 | 20453000 |
| Pubmed | E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. | MAGEB4 ARHGEF33 WIZ MTHFD1 PCLO DGKH ADIPOR2 | 8.27e-04 | 736 | 72 | 7 | 29676528 |
| Pubmed | Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. | CYFIP1 WIZ PDCD6IP HECW1 NSD1 PKN1 ARHGEF2 GOLGB1 | 8.40e-04 | 963 | 72 | 8 | 28671696 |
| Pubmed | Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. | MTHFD1 KANK3 ETV6 ARHGEF2 POFUT2 ADIPOR2 | 8.61e-04 | 536 | 72 | 6 | 15840001 |
| Pubmed | Exchangeable gene trap using the Cre/mutated lox system. | MTHFD1 KANK3 ETV6 ARHGEF2 POFUT2 ADIPOR2 | 8.78e-04 | 538 | 72 | 6 | 10512203 |
| Pubmed | N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease. | ARHGAP17 MSH3 PLEC PLIN3 GOLGB1 | 9.16e-04 | 360 | 72 | 5 | 33111431 |
| Pubmed | Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. | PDCD6IP KAT6A TNK2 ASTN2 PKN1 DGKH PALS2 GOLGB1 KDM4B SBNO2 | 9.60e-04 | 1489 | 72 | 10 | 28611215 |
| Pubmed | Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach. | PSMC6 MSH3 ARHGEF2 SHOC2 | 9.81e-04 | 211 | 72 | 4 | 17314511 |
| Pubmed | A High-Density Human Mitochondrial Proximity Interaction Network. | WIZ PCLO DDX18 PEX6 PSMC6 TWNK DGKH ALDH4A1 ARHGEF2 GOLGB1 | 9.95e-04 | 1496 | 72 | 10 | 32877691 |
| Pubmed | Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex. | CYFIP1 PSMC6 ARHGEF2 SLC3A2 | 1.05e-03 | 215 | 72 | 4 | 30462309 |
| Pubmed | Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers. | CYFIP1 ABCF3 PDCD6IP MTHFD1 DDX18 PSMC6 ARHGEF2 DOT1L PLIN3 | 1.07e-03 | 1247 | 72 | 9 | 27684187 |
| Pubmed | Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved. | CYFIP1 PDCD6IP PSMC6 SLC3A2 | 1.09e-03 | 217 | 72 | 4 | 30619736 |
| Pubmed | Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma. | AURKA CYFIP1 PDCD6IP MTHFD1 DDX18 UGGT1 PLEC ARHGEF2 SLC3A2 | 1.13e-03 | 1257 | 72 | 9 | 36526897 |
| Pubmed | Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver. | MTHFD1 PEX6 | 1.13e-03 | 24 | 72 | 2 | 17937387 |
| Pubmed | IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5. | CYFIP1 HTATSF1 PSMC6 SLC3A2 | 1.16e-03 | 221 | 72 | 4 | 31950832 |
| Pubmed | Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification. | WIZ DDX18 MSH3 ARHGEF2 | 1.18e-03 | 222 | 72 | 4 | 37071664 |
| Pubmed | Identifying biological pathways that underlie primordial short stature using network analysis. | PDCD6IP MTHFD1 DDX18 UGGT1 PLEC ARHGEF2 GOLGB1 SLC3A2 | 1.24e-03 | 1024 | 72 | 8 | 24711643 |
| Pubmed | The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. | AURKA DGKH ARHGEF2 SLC3A2 | 1.28e-03 | 227 | 72 | 4 | 26410627 |
| Pubmed | Functional genomics identifies therapeutic targets for MYC-driven cancer. | HPS1 ARFGEF2 PKN1 | 1.30e-03 | 103 | 72 | 3 | 22623531 |
| Pubmed | EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma. | CYFIP1 PDCD6IP MTHFD1 PSMC6 PLEC PLIN3 SLC3A2 | 1.37e-03 | 803 | 72 | 7 | 36517590 |
| Pubmed | Identification and functional characterization of transcriptional activators in human cells. | WIZ PDCD6IP PCLO DOT1L KDM4B | 1.43e-03 | 398 | 72 | 5 | 35016035 |
| Pubmed | Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome. | ARHGEF2 GOLGB1 | 1.43e-03 | 27 | 72 | 2 | 18685082 |
| Pubmed | USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma. | DNHD1 NSD1 PLEC GOLGB1 | 1.44e-03 | 234 | 72 | 4 | 36243803 |
| Interaction | HDAC6 interactions | AURKA ABCF3 OTULIN MTHFD1 DDX18 ETV6 HTATSF1 PSMC6 ALDH4A1 MSH3 PLEC ARHGEF2 GOLGB1 SLC3A2 | 3.67e-06 | 929 | 71 | 14 | int:HDAC6 |
| Interaction | WDR5 interactions | PDCD6IP DDX18 KAT6A PSMC6 PKN1 ALDH4A1 PLEC ARHGEF2 DOT1L TAF6 TADA3 PLIN3 GOLGB1 KDM4B SLC3A2 | 5.35e-06 | 1101 | 71 | 15 | int:WDR5 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr19p13 | WIZ KANK3 PALM3 PKN1 DOT1L PLIN3 KDM4B SBNO2 | 3.58e-05 | 797 | 72 | 8 | chr19p13 |
| Cytoband | 19p13.3 | DOT1L PLIN3 KDM4B SBNO2 | 5.41e-04 | 237 | 72 | 4 | 19p13.3 |
| Cytoband | 19p13.12 | PALM3 PKN1 | 2.83e-03 | 50 | 72 | 2 | 19p13.12 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr10q24 | HPS1 FBXL15 TWNK | 3.32e-03 | 189 | 72 | 3 | chr10q24 |
| Drug | Adamantamine fumarate [80789-67-9]; Up 200; 9.6uM; HL60; HT_HG-U133A | WIZ HPS1 PEX6 FBXL15 TNK2 PKN1 KDM4B | 2.89e-06 | 196 | 72 | 7 | 1344_UP |
| Disease | Sarcosine measurement | PEX6 SHOC2 PCDHGA8 | 1.92e-05 | 23 | 67 | 3 | EFO_0021668 |
| Disease | cannabis dependence measurement | SEMA3D ARHGEF33 DDX18 | 1.80e-04 | 48 | 67 | 3 | EFO_0008457 |
| Disease | acute myeloid leukemia (is_implicated_in) | KAT6A NSD1 ETV6 | 9.35e-04 | 84 | 67 | 3 | DOID:9119 (is_implicated_in) |
| Disease | non-high density lipoprotein cholesterol measurement | LIPA UBXN2B DDX18 NSD1 ARFGEF2 PEX6 COG5 | 1.16e-03 | 713 | 67 | 7 | EFO_0005689 |
| Disease | aspartate aminotransferase to alanine aminotransferase ratio | LIPA UBXN2B PEX6 PLEC | 2.16e-03 | 239 | 67 | 4 | EFO_0010934 |
