Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentside of membrane

BMPR1A AP2A2 RASA3 ADAM9 LRRK2 CCR7 ITGA2 ITGA2B ITGAM LEPR STAC HYAL2 IL6ST

8.20e-058758913GO:0098552
GeneOntologyCellularComponentprotein complex involved in cell adhesion

ITGA2 ITGA2B ITGAM TNXB

1.17e-0459894GO:0098636
GeneOntologyCellularComponentaxon terminus

ELFN1 CDHR3 LRRK2 ITGA2 USH2A CNGA1

2.78e-04210896GO:0043679
GeneOntologyCellularComponentintegrin complex

ITGA2 ITGA2B ITGAM

3.38e-0432893GO:0008305
GeneOntologyCellularComponentexternal side of plasma membrane

BMPR1A ADAM9 CCR7 ITGA2 ITGA2B ITGAM LEPR HYAL2 IL6ST

3.65e-04519899GO:0009897
GeneOntologyCellularComponentneuron projection terminus

ELFN1 CDHR3 LRRK2 ITGA2 USH2A CNGA1

4.83e-04233896GO:0044306
GeneOntologyCellularComponentplasma membrane protein complex

ERBB2 BMPR1A IGF1R DPP10 AP2A2 CATSPERD CDHR3 ITGA2 ITGA2B ITGAM IL6ST

4.95e-047858911GO:0098797
GeneOntologyCellularComponentdistal axon

BOC ELFN1 USP9X CDHR3 LRRK2 ITGA2 USH2A CNGA1

5.35e-04435898GO:0150034
GeneOntologyCellularComponentmembrane protein complex

ERBB2 BMPR1A IGF1R DPP10 APOO AP2A2 CATSPERD SEC24A CDHR3 GABRQ LAMTOR3 ITGA2 ITGA2B ITGAM CNGA1 IL6ST

5.35e-0414988916GO:0098796
GeneOntologyCellularComponentplasma membrane signaling receptor complex

ERBB2 BMPR1A IGF1R ITGA2 ITGA2B ITGAM IL6ST

7.39e-04350897GO:0098802
GeneOntologyCellularComponentreceptor complex

ERBB2 BMPR1A IGF1R GABRQ ITGA2 ITGA2B ITGAM LEPR IL6ST

8.20e-04581899GO:0043235
DomainFN3

BOC IGF1R KALRN USH2A TNXB LEPR IL6ST

2.32e-05185867SM00060
DomainFN3

BOC IGF1R KALRN USH2A TNXB LEPR IL6ST

3.70e-05199867PS50853
DomainFN3_dom

BOC IGF1R KALRN USH2A TNXB LEPR IL6ST

5.05e-05209867IPR003961
DomainIntegrin_alpha_C_CS

ITGA2 ITGA2B ITGAM

5.05e-0516863IPR018184
DomainIntegrin_alpha-2

ITGA2 ITGA2B ITGAM

7.32e-0518863IPR013649
DomainIntegrin_alpha2

ITGA2 ITGA2B ITGAM

7.32e-0518863PF08441
DomainIntegrin_alpha

ITGA2 ITGA2B ITGAM

7.32e-0518863IPR000413
DomainINTEGRIN_ALPHA

ITGA2 ITGA2B ITGAM

7.32e-0518863PS00242
DomainInt_alpha_beta-p

ITGA2 ITGA2B ITGAM

8.66e-0519863IPR013519
DomainInt_alpha

ITGA2 ITGA2B ITGAM

8.66e-0519863SM00191
DomainVWF_A

HMCN1 SEC24A ITGA2 ITGAM CFB

9.37e-0599865IPR002035
Domainfn3

BOC IGF1R KALRN USH2A TNXB IL6ST

1.03e-04162866PF00041
DomainIgC2-like_lig-bd

LEPR IL6ST

1.25e-044862IPR010457
DomainG8

PKHD1L1 CEMIP2

1.25e-044862PF10162
DomainG8_domain

PKHD1L1 CEMIP2

1.25e-044862IPR019316
DomainG8

PKHD1L1 CEMIP2

1.25e-044862PS51484
DomainLep_receptor_Ig

LEPR IL6ST

1.25e-044862PF06328
DomainG8

PKHD1L1 CEMIP2

1.25e-044862SM01225
DomainFG_GAP

ITGA2 ITGA2B ITGAM

1.36e-0422863PS51470
DomainFG-GAP

ITGA2 ITGA2B ITGAM

1.78e-0424863PF01839
DomainFG-GAP

ITGA2 ITGA2B ITGAM

1.78e-0424863IPR013517
DomainIntegrin_dom

ITGA2 ITGA2B ITGAM

2.01e-0425863IPR032695
Domain-

DPP10 DPP8

3.11e-0468622.140.10.30
DomainDPPIV_N

DPP10 DPP8

3.11e-046862PF00930
DomainPeptidase_S9B_N

DPP10 DPP8

3.11e-046862IPR002469
DomainFurin-like

ERBB2 IGF1R

4.34e-047862PF00757
DomainRcpt_L-dom

ERBB2 IGF1R

4.34e-047862IPR000494
DomainHematopoietin_rcpt_Gp130_CS

LEPR IL6ST

4.34e-047862IPR003529
DomainFurin-like_Cys-rich_dom

ERBB2 IGF1R

4.34e-047862IPR006211
DomainRecep_L_domain

ERBB2 IGF1R

4.34e-047862PF01030
Domain-

ERBB2 IGF1R

4.34e-0478623.80.20.20
DomainVWFA

HMCN1 ITGA2 ITGAM CFB

5.58e-0482864PS50234
DomainHEMATOPO_REC_L_F2

LEPR IL6ST

5.76e-048862PS01353
DomainPectin_lyase_fold/virulence

PKHD1L1 CEMIP2

5.76e-048862IPR011050
DomainVWA

HMCN1 ITGA2 ITGAM CFB

6.11e-0484864SM00327
DomainEGF

BMP1 FCGBP HMCN1 ADAM9 TNXB HYAL2

7.56e-04235866SM00181
DomainGrowth_fac_rcpt_

BMP1 ERBB2 IGF1R HMCN1 TNXB

7.70e-04156865IPR009030
Domain-

BOC AREL1 IGF1R HMCN1 KALRN USH2A PKHD1L1 TNXB LEPR IL6ST

9.26e-0466386102.60.40.10
DomainEGF-like_dom

BMP1 FCGBP HMCN1 ADAM9 TNXB HYAL2

1.02e-03249866IPR000742
DomainIntegrin_alpha

ITGA2B ITGAM

1.12e-0311862PF00357
DomainPeptidase_S9

DPP10 DPP8

1.12e-0311862PF00326
DomainPeptidase_S9

DPP10 DPP8

1.12e-0311862IPR001375
DomainEGF_1

BMP1 HMCN1 ADAM9 USH2A TNXB HYAL2

1.15e-03255866PS00022
DomainIg-like_fold

BOC AREL1 IGF1R HMCN1 KALRN USH2A PKHD1L1 TNXB LEPR IL6ST

1.48e-037068610IPR013783
DomainGlycoside_hydrolase_SF

GLB1L3 HYAL2 MGAM2

1.87e-0353863IPR017853
DomainVWA

ITGA2 ITGAM CFB

2.19e-0356863PF00092
DomainFurin_repeat

ERBB2 IGF1R

3.06e-0318862IPR006212
DomainFU

ERBB2 IGF1R

3.06e-0318862SM00261
DomainRNaseH-like_dom

PIWIL4 PNLDC1 PRPF8

3.97e-0369863IPR012337
DomainL_dom-like

ERBB2 IGF1R LRRC19 ELFN1 LRRK2 TLR9

4.06e-03328866IPR032675
DomainCupredoxin

PRPF8 PKHD1L1

4.56e-0322862IPR008972
DomainEGF_3

BMP1 HMCN1 ADAM9 TNXB HYAL2

4.61e-03235865PS50026
Pubmed

Ancient ubiquitous protein 1 binds to the conserved membrane-proximal sequence of the cytoplasmic tail of the integrin alpha subunits that plays a crucial role in the inside-out signaling of alpha IIbbeta 3.

ITGA2 ITGA2B ITGAM

5.63e-07789312042322
Pubmed

Insulin-like growth factor-1 receptor expression masks the antiinflammatory and glucose uptake capacity of insulin in vascular smooth muscle cells.

IGF1R LEPR

6.48e-06289219122171
Pubmed

Platelet collagen receptor alpha2beta1 integrin and glycoprotein IIIa Pl(A1/A2) polymorphisms are not associated with nephropathy in type 2 diabetes.

ITGA2 ITGA2B

6.48e-06289211728949
Pubmed

Superior antitumor activity of a novel bispecific antibody cotargeting human epidermal growth factor receptor 2 and type I insulin-like growth factor receptor.

ERBB2 IGF1R

6.48e-06289224227890
Pubmed

Platelet receptor HPA-1 polymorphism of alphaIIbbeta3 and 807 C/T polymorphism of alpha2beta1 and Buerger's disease.

ITGA2 ITGA2B

6.48e-06289217495265
Pubmed

Evasion mechanisms to Igf1r inhibition in rhabdomyosarcoma.

ERBB2 IGF1R

6.48e-06289221447712
Pubmed

Potent anti-proliferative effects of metformin on trastuzumab-resistant breast cancer cells via inhibition of erbB2/IGF-1 receptor interactions.

ERBB2 IGF1R

6.48e-06289221862872
Pubmed

Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling.

ERBB2 IGF1R

6.48e-06289217761519
Pubmed

BMPR1A-mediated BMP1 signalling is disrupted in the cadmium-induced omphalocele in the chick model.

BMP1 BMPR1A

6.48e-06289221258932
Pubmed

IGF-1R and Leptin Expression Profile and the Effects of Metformin Treatment on Metabolic and Endocrine Parameters in PCOS Mice.

IGF1R LEPR

6.48e-06289229430464
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

SLC30A7 TMUB1 ZNF106 GTF2A1 IGF1R IPO8 AP2A2 ADAM9 SLFN5 ITGA2 PRPF8 CEMIP2 ACSL5

1.17e-051203891329180619
Pubmed

Epidermal growth factor receptor (EGFR), HER2 and insulin-like growth factor-1 receptor (IGF-1R) status in ovarian adult granulosa cell tumours.

ERBB2 IGF1R

1.94e-05389224206174
Pubmed

miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer.

ERBB2 IGF1R

1.94e-05389224655723
Pubmed

Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R.

ERBB2 IGF1R

1.94e-05389224571711
Pubmed

Polymorphism of human platelet alloantigen in Chinese patients with acute myocardial infarction and acute ischemic stroke.

ITGA2 ITGA2B

1.94e-05389211776052
Pubmed

Collagen platelet receptor polymorphisms integrin alpha2beta1 C807T and GPVI Q317L and risk of ischemic stroke.

ITGA2 ITGA2B

1.94e-05389212871362
Pubmed

Association of the gene polymorphisms of platelet glycoprotein Ia and IIb/IIIa with myocardial infarction and extent of coronary artery disease in the Korean population.

ITGA2 ITGA2B

1.94e-05389215227729
Pubmed

The EGF receptor interacts with the type 1 IGF receptor and regulates its stability.

ERBB2 IGF1R

1.94e-05389217307140
Pubmed

Heterotrimerization of the growth factor receptors erbB2, erbB3, and insulin-like growth factor-i receptor in breast cancer cells resistant to herceptin.

ERBB2 IGF1R

1.94e-05389220103628
Pubmed

Are prothrombotic variants of platelet glycoprotein receptor polymorphisms involved in the pathogenesis of thrombotic microangiopathies?

ITGA2 ITGA2B

1.94e-05389218502778
Pubmed

Dual inhibition of IGF1R and ER enhances response to trastuzumab in HER2 positive breast cancer cells.

ERBB2 IGF1R

1.94e-05389228498399
Pubmed

Expression and clinical significance of leptin, the functional receptor of leptin (OB-Rb) and HER-2 in non-small-cell lung cancer: a retrospective analysis.

ERBB2 LEPR

1.94e-05389221927908
Pubmed

HPA polymorphism in sub-Saharan African populations: Beninese, Cameroonians, Congolese, and Pygmies.

ITGA2 ITGA2B

1.94e-05389215730528
Pubmed

Hyaluronan degradation by HYAL2 is essential for odontoblastic differentiation and migration of mouse dental papilla cells.

HYAL2 CEMIP2

1.94e-05389238490466
Pubmed

Phosphoenolpyruvate-dependent inhibition of collagen biosynthesis, alpha2beta1 integrin and IGF-I receptor signaling in cultured fibroblasts.

IGF1R ITGA2

1.94e-05389218491034
Pubmed

Immuno-proteomic discovery of tumor tissue autoantigens identifies olfactomedin 4, CD11b, and integrin alpha-2 as markers of colorectal cancer with liver metastases.

ITGA2 ITGAM

1.94e-05389228669815
Pubmed

Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body.

TRPM7 LEPR

1.94e-05389231545149
Pubmed

Gene frequencies of human platelet antigens in the Macedonian population.

ITGA2 ITGA2B

1.94e-05389216573563
Pubmed

Microarray-based genotyping for blood groups: comparison of gene array and 5'-nuclease assay techniques with human platelet antigen as a model.

ITGA2 ITGA2B

1.94e-05389215847651
Pubmed

High-throughput genotyping of human platelet antigens using the 5'-nuclease assay and minor groove binder probe technology.

ITGA2 ITGA2B

1.94e-05389215355503
Pubmed

Relationship between platelet activation related factors and polymorphism of related genes in patients with coronary heart disease of blood-stasis syndrome.

ITGA2 ITGA2B

1.94e-05389219082798
Pubmed

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection.

TLR9 ITGAM

1.94e-05389218614760
Pubmed

Transactivation of erbB2 by short and long isoforms of leptin receptors.

ERBB2 LEPR

1.94e-05389215135067
Pubmed

Gene frequencies of human platelet antigens 1-5 in indigenous Australians in Western Australia.

ITGA2 ITGA2B

1.94e-05389212071877
Pubmed

Gene frequencies of human platelet alloantigens in Bahraini Arabs.

ITGA2 ITGA2B

1.94e-05389217160992
Pubmed

Next-generation sequencing to solve complex inherited retinal dystrophy: A case series of multiple genes contributing to disease in extended families.

PRPF8 USH2A

1.94e-05389228761320
Pubmed

Impact of insulin-like growth factor type 1 receptor, epidermal growth factor receptor, and HER2 expressions on outcomes of patients with gastric cancer.

ERBB2 IGF1R

1.94e-05389218483367
Pubmed

Role of 4 platelet membrane glycoprotein polymorphisms on experimental arterial thrombus formation in men.

ITGA2 ITGA2B

1.94e-05389211698306
Pubmed

HPA-genotyping and antiplatelet antibodies in female blood donors.

ITGA2 ITGA2B

1.94e-05389214671618
Pubmed

MiR-1275 promotes cell migration, invasion and proliferation in squamous cell carcinoma of head and neck via up-regulating IGF-1R and CCR7.

IGF1R CCR7

1.94e-05389229278769
Pubmed

Platelet glycoprotein gene Ia C807T, HPA-3, and Ibα VNTR polymorphisms are associated with increased ischemic stroke risk: Evidence from a comprehensive meta-analysis.

ITGA2 ITGA2B

1.94e-05389228004990
Pubmed

Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells.

ERBB2 IGF1R

1.94e-05389214697248
Pubmed

Role of five platelet membrane glycoprotein polymorphisms in branch retinal vein occlusion.

ITGA2 ITGA2B

1.94e-05389216905953
Pubmed

Infiltrating CD11b+CD11c+ cells have the potential to mediate inducible nitric oxide synthase-dependent cell death in mammary carcinomas of HER-2/neu transgenic mice.

ERBB2 ITGAM

1.94e-05389219653277
Pubmed

Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases.

DPP10 DPP8

1.94e-05389212662155
Pubmed

c-erbB2-induced disruption of matrix adhesion and morphogenesis reveals a novel role for protein kinase B as a negative regulator of alpha(2)beta(1) integrin function.

ERBB2 ITGA2

1.94e-05389212181354
Pubmed

Glycoprotein 130 receptor signaling mediates α-cell dysfunction in a rodent model of type 2 diabetes.

LEPR IL6ST

1.94e-05389224812426
Pubmed

Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2.

LRRK2 LEPR

1.94e-05389222357653
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

DPT APOO HMCN1 TNXB

2.26e-056489422261194
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

AP2A2 MTHFD1 USP9X SEC24A ITGA2B PRPF8 ITGAM

3.00e-0534489730333137
Pubmed

Mycobacterial hypersensitivity pneumonitis requires TLR9-MyD88 in lung CD11b+ CD11c+ cells.

TLR9 ITGAM

3.87e-05489221273385
Pubmed

Mean platelet volume and integrin alleles correlate with levels of integrins α(IIb)β(3) and α(2)β(1) in acute coronary syndrome patients and normal subjects.

ITGA2 ITGA2B

3.87e-05489222015659
Pubmed

Conventional and monocyte-derived CD11b(+) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen.

CCR7 ITGAM

3.87e-05489223352232
Pubmed

No evidence for involvement of prothrombotic platelet receptor polymorphisms in acute coronary stent thrombosis.

ITGA2 ITGA2B

3.87e-05489217346829
Pubmed

Hemicentin 1 influences podocyte dynamic changes in glomerular diseases.

HMCN1 LEPR

3.87e-05489229488390
Pubmed

Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast cancer progression in vivo.

ERBB2 IGF1R

3.87e-05489225241146
Pubmed

Double heterozygosity polymorphisms for platelet glycoproteins Ia/IIa and IIb/IIIa increases arterial thrombosis and arteriosclerosis in patients with the antiphospholipid syndrome or with systemic lupus erythematosus.

ITGA2 ITGA2B

3.87e-05489217728329
Pubmed

Prognostic importance of PTEN, EGFR, HER-2, and IGF-1R in gastric cancer patients treated with postoperative chemoradiation.

ERBB2 IGF1R

3.87e-05489231318186
Pubmed

Gene frequencies of platelet-specific antigens in Croatian population.

ITGA2 ITGA2B

3.87e-05489219778317
Pubmed

An unexpected biochemical and functional interaction between gp130 and the EGF receptor family in breast cancer cells.

ERBB2 IL6ST

3.87e-05489211821958
Pubmed

Association of polymorphisms of platelet membrane integrins alpha IIb(beta)3 (HPA-1b/Pl) and alpha2(beta)1 (alpha807TT) with premature myocardial infarction.

ITGA2 ITGA2B

3.87e-05489215978110
Pubmed

Inactivation of Rac1 reduces Trastuzumab resistance in PTEN deficient and insulin-like growth factor I receptor overexpressing human breast cancer SKBR3 cells.

ERBB2 IGF1R

3.87e-05489221943825
Pubmed

IRS-2 deubiquitination by USP9X maintains anchorage-independent cell growth via Erk1/2 activation in prostate carcinoma cell line.

IGF1R USP9X

3.87e-05489230338032
Pubmed

Insulin-like growth factor-1 receptor signaling increases the invasive potential of human epidermal growth factor receptor 2-overexpressing breast cancer cells via Src-focal adhesion kinase and forkhead box protein M1.

ERBB2 IGF1R

3.87e-05489225391374
Pubmed

Human platelet antigens polymorphisms and susceptibility of thrombosis in hemodialysis patients.

ITGA2 ITGA2B

3.87e-05489218638089
Pubmed

Human platelet alloantigens (HPA) 1, HPA2, HPA3, HPA4, and HPA5 polymorphisms in sickle cell anemia patients with vaso-occlusive crisis.

ITGA2 ITGA2B

3.87e-05489219702628
Pubmed

The BC genotype of the VNTR polymorphism of platelet glycoprotein Ibalpha is overrepresented in patients with recurrent stroke regardless of aspirin therapy.

ITGA2 ITGA2B

3.87e-05489217630485
Pubmed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.

ITGA2 ITGA2B ITGAM

4.53e-052789331541017
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

FCGBP ITGA2B TNXB LEPR IL6ST CFB

5.34e-0525789616335952
Pubmed

Modulation of ADP-induced platelet activation by aspirin and pravastatin: role of lectin-like oxidized low-density lipoprotein receptor-1, nitric oxide, oxidative stress, and inside-out integrin signaling.

ITGA2 ITGA2B

6.44e-05589217538005
Pubmed

The polymorphism of platelet membrane integrin alpha2beta1 (alpha2807TT) is associated with premature onset of fetal loss.

ITGA2 ITGA2B

6.44e-05589215630502
Pubmed

Microbe-dependent lymphatic migration of neutrophils modulates lymphocyte proliferation in lymph nodes.

CCR7 ITGAM

6.44e-05589225972253
Pubmed

Pro-collagenase-1 (matrix metalloproteinase-1) binds the alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagen.

ITGA2 ITGA2B

6.44e-05589211359786
Pubmed

Conservation of the linkage of the murine Itga2b and Itgb3 loci in mouse chromosome 11.

ERBB2 ITGA2B

6.44e-05589210337632
Pubmed

Talin is required for integrin-mediated platelet function in hemostasis and thrombosis.

ITGA2 ITGA2B

6.44e-05589218086863
Pubmed

Analysis of expression of membrane-bound tumor markers in ductal carcinoma in situ of the breast: paving the way for molecular imaging.

ERBB2 IGF1R

6.44e-05589223744486
Pubmed

Human platelet antigen polymorphisms (HPA-1, -2, -3, -4, -5 and -15) in major ethnic groups of Pakistan.

ITGA2 ITGA2B

6.44e-05589219948007
Pubmed

Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification.

ITGA2B ITGAM

6.44e-05589220228271
Pubmed

Decorin regulates endothelial cell motility on collagen I through activation of insulin-like growth factor I receptor and modulation of alpha2beta1 integrin activity.

IGF1R ITGA2

6.44e-05589218413316
Pubmed

Human platelet antigen allele frequencies in different Algerian populations.

ITGA2 ITGA2B

6.44e-05589220149160
Pubmed

Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip.

PRPF8 USH2A CNGA1 CFB

7.58e-058789420801516
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

IPO8 KALRN NUP62CL USP9X MICAL3 ITGA2 TNXB NOL8

8.76e-0555289810737800
Pubmed

Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways.

TLR9 ITGAM

9.65e-05689212244198
Pubmed

Platelet receptor and clotting factor polymorphisms as genetic risk factors for thromboembolic complications in heparin-induced thrombocytopenia.

ITGA2 ITGA2B

9.65e-05689212724616
Pubmed

Integrins take partners: cross-talk between integrins and other membrane receptors.

ITGA2 ITGA2B

9.65e-0568929789327
Pubmed

Simultaneous genotyping of human platelet antigen-1 to 17w by polymerase chain reaction sequence-based typing.

ITGA2 ITGA2B

9.65e-05689219570064
Pubmed

Somatic mutation of epidermal growth factor receptor in a small subset of cutaneous squamous cell carcinoma.

ERBB2 IGF1R

9.65e-05689219812598
Pubmed

A new class of obesity genes encodes leukocyte adhesion receptors.

ITGAM LEPR

9.65e-0568929207125
Pubmed

Gene frequency of human platelet alloantigens-1 to -6 and -15 in Saudi blood donors.

ITGA2 ITGA2B

9.65e-05689227019315
Pubmed

Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia.

BMPR1A IGF1R

9.65e-05689216886151
Pubmed

The small GTPase Rap1b regulates the cross talk between platelet integrin alpha2beta1 and integrin alphaIIbbeta3.

ITGA2 ITGA2B

9.65e-05689216357324
Pubmed

Involvement of transmembrane domain interactions in signal transduction by alpha/beta integrins.

ITGA2 ITGA2B

9.65e-05689214681217
Pubmed

The allele frequencies of HPA 1-16 determined by PCR-SSP in Chinese Cantonese donors.

ITGA2 ITGA2B

9.65e-05689220667040
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ERBB2 IGF1R RASA3 MICAL3 ITGA2 CEMIP2 WDR48

1.06e-0442189736976175
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

ERBB2 BMPR1A IGF1R AP2A2 MTHFD1 USP9X HIPK1 ADAM9 DPP8

1.07e-0473089934857952
Pubmed

Association of human platelet alloantigen 1 through 5 polymorphisms with ischemic stroke.

ITGA2 ITGA2B

1.35e-04789218057877
Pubmed

Localization of extracellular matrix molecules, integrins and their regulators, TGF betas, is correlated with axon pathfinding in the spinal cord of normal and Danforth's short tail mice.

ITGA2 ITGA2B

1.35e-0478929427478
Pubmed

Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease.

ITGA2 ITGA2B

1.35e-04789219132198
Pubmed

Arthritis critically dependent on innate immune system players.

ITGAM CFB

1.35e-04789211869678
Pubmed

CD11b suppresses TLR activation of nonclassical monocytes to reduce primary graft dysfunction after lung transplantation.

TLR9 ITGAM

1.35e-04789235838047
Cytoband15q21

TRPM7 MYO5C

2.02e-041189215q21
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ERBB2 BMPR1A IGF1R CCR7 ITGA2 ITGA2B TLR9 ITGAM LEPR IL6ST

3.74e-073945710471
GeneFamilyFibronectin type III domain containing

BOC IGF1R KALRN ELFN1 USH2A TNXB IL6ST

6.80e-07160577555
GeneFamilyCD molecules|Integrin alpha subunits

ITGA2 ITGA2B ITGAM

2.34e-05185731160
GeneFamilyCD molecules|DASH family

DPP10 DPP8

2.03e-0475721205
GeneFamilyApolipoproteins

APOO APOF

1.97e-0321572405
GeneFamilyAcyl-CoA synthetase family

ACSF2 ACSL5

3.02e-032657240
CoexpressionHAY_BONE_MARROW_CD34_POS_MKP

EFHC2 KALRN ITGA2 ITGA2B STAC

2.62e-0664895M39187
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

HMCN1 CHSY1 PKHD1L1 LEPR HYAL2 IL6ST CEMIP2

9.89e-081878977876dcb4800c2e54874df3d933efb79307a64a97
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BOC PRR5L KALRN PKHD1L1 HYAL2 IL6ST CEMIP2

1.10e-07190897656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCellClub-club-3|World / Class top

FCGBP TLR9 PKHD1L1 CNGA1 CFB MYO5C

1.28e-0617289634fbb82a2ec77dd183cf26b38edeb7e936b707bc
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

KALRN CARD10 MICAL3 PKHD1L1 TNXB HYAL2

2.14e-06188896aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

HMCN1 CHSY1 PKHD1L1 LEPR IL6ST CEMIP2

2.21e-061898967346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

HMCN1 CHSY1 PKHD1L1 LEPR IL6ST CEMIP2

2.21e-0618989675c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

HMCN1 CHSY1 PKHD1L1 LEPR IL6ST CEMIP2

2.21e-06189896c81787a8c662db5d7814c583dd64562857629e81
ToppCellfacs-Heart-RV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFHC2 HMCN1 PKHD1L1 HYAL2 IL6ST CEMIP2

2.35e-06191896f0c649bb32732c9dd38a0af8ce94d2a4d16de39a
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFHC2 HMCN1 PKHD1L1 HYAL2 IL6ST CEMIP2

2.35e-06191896e518c598719119e60c76016c586b1520c258bbcb
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

HMCN1 CHSY1 PKHD1L1 LEPR IL6ST CEMIP2

2.42e-06192896c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

HMCN1 CHSY1 PKHD1L1 LEPR IL6ST CEMIP2

2.49e-0619389601c2df9206f1527c578e808978e58196c35e72f5
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

HMCN1 CHSY1 PKHD1L1 LEPR IL6ST CEMIP2

2.49e-061938962531266bc57339d4e2b22a88817008e32b8c1598
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

HMCN1 CHSY1 PKHD1L1 LEPR IL6ST CEMIP2

2.57e-06194896b6cc849fa08599bff9839ef382d190cc964e273e
ToppCelldistal-Endothelial-Vein-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHSY1 PKHD1L1 LEPR HYAL2 IL6ST CEMIP2

3.06e-06200896ff88d28162e0231d5dac0e0c6bec98fa8da58a23
ToppCellmedial-Endothelial-Vein-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHSY1 PKHD1L1 LEPR HYAL2 IL6ST CEMIP2

3.06e-062008963f689029f5bc7db0af50a405f1e252aeec529077
ToppCelldistal-2-Endothelial-Vein|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHSY1 PKHD1L1 LEPR HYAL2 IL6ST CEMIP2

3.06e-062008962785225956d2422acab90e99b7debe3709cf3308
ToppCellmedial-Endothelial-Vein|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHSY1 PKHD1L1 LEPR HYAL2 IL6ST CEMIP2

3.06e-062008961163e5f6dfb304c94bf8885629350454f4b6bee8
ToppCellmedial-2-Endothelial-Vein|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHSY1 PKHD1L1 LEPR HYAL2 IL6ST CEMIP2

3.06e-0620089649da4e3ff10262a492c2cf566a7f2e35e418bfda
ToppCelldroplet-Marrow-BM-30m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBP1 HIPK1 SLFN5 ITGAM CFB

1.74e-05160895822adcf5f9208f305cafffd8ed97f3a061e82b03
ToppCelldroplet-Marrow-BM-30m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBP1 HIPK1 SLFN5 ITGAM CFB

1.85e-0516289576e289ad9fd3694f77fd0d19e74c1cb8e87b8094
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

CARD10 SLFN5 ITGA2 USH2A CEMIP2

1.91e-05163895d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

BMP1 ZNF106 CATSPERD CDHR3 FLACC1

2.08e-051668954b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN1 SLFN5 HYAL2 IL6ST CEMIP2

2.27e-0516989558136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN1 SLFN5 HYAL2 IL6ST CEMIP2

2.27e-0516989504c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCellwk_15-18-Hematologic-Meg-ery-Megakaryocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EFHC2 KALRN RASA3 ITGA2B PKHD1L1

2.27e-05169895d571e84e01e3316748d4407ed98881b17484e035
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DPP10 PNLDC1 PKHD1L1 CFB MYO5C

2.54e-051738953d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DPP10 PNLDC1 PKHD1L1 CFB MYO5C

2.54e-051738953aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

BMPR1A KALRN RNF212 CCR7 LEPR

2.54e-05173895090dc3c5bd2652a65c2490fc889da858c3af368f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLFN5 TNXB HYAL2 IL6ST ACSL5

2.68e-0517589590302e8a44858ef3b2a165b88284d4788d591a99
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

BOC DPT HMCN1 TNXB LEPR

2.75e-05176895510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRR5L KALRN CARD10 PKHD1L1 TNXB

2.83e-05177895227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRR5L KALRN CARD10 PKHD1L1 TNXB

2.83e-0517789566ffa279147961080c104242a08b176e301d80e3
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRR5L KALRN CARD10 PKHD1L1 TNXB

2.83e-051778950cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BOC BMP1 LRRK2 ITGA2 MYO5C

2.99e-05179895fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell10x5'v1-week_17-19-Hematopoietic-MK-early_MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EFHC2 KALRN GABRQ ITGA2B STAC

2.99e-05179895d5b9c610c1519804b1753fed1b505293ea590867
ToppCellfacs-SCAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP1 AP2A2 SLFN5 ITGA2B CFB

3.07e-051808956c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 PKHD1L1 HYAL2 IL6ST CEMIP2

3.15e-05181895cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 PKHD1L1 HYAL2 IL6ST CEMIP2

3.32e-051838956c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BOC BMP1 LRRK2 ACSL5 MYO5C

3.40e-05184895ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 SLFN5 DPP8 PKHD1L1 CEMIP2

3.59e-051868950ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BOC BMP1 LRRK2 ACSL5 MYO5C

3.59e-05186895e83718fabb057100835d3357df407f283d23fe16
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

BOC DPT HMCN1 TNXB LEPR

3.68e-05187895bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

TRPM7 USP9X HIPK1 IL6ST CEMIP2

3.77e-05188895ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

KALRN CARD10 PKHD1L1 TNXB HYAL2

3.77e-0518889580910dcbb51990f2baed240f319456c0d3fa2065
ToppCellEndothelial-B|World / lung cells shred on cell class, cell subclass, sample id

KALRN CARD10 PKHD1L1 TNXB HYAL2

3.77e-051888955959a88728812a5f4cbfa54eddc7a73ccbaa2f68
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

KALRN CARD10 MICAL3 PKHD1L1 TNXB

3.77e-05188895c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BOC BMP1 LRRK2 ITGA2 MYO5C

3.77e-051888954bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellfacs-MAT-Fat-3m|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC BMP1 USP9X PRPF8 IL6ST

3.77e-051888957da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 PKHD1L1 HYAL2 IL6ST CEMIP2

3.87e-051898958e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NEIL2 PTGR2 PKHD1L1 LEPR HYAL2

3.87e-051898950739baad9a7da511dd3d7249f84299aee88370a1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN1 TRPM7 ITGA2 STAC MYO5C

3.87e-05189895975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN1 TRPM7 ITGA2 STAC MYO5C

3.87e-051898957eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 PKHD1L1 HYAL2 IL6ST CEMIP2

3.87e-05189895fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

KALRN CARD10 PKHD1L1 TNXB HYAL2

3.97e-051908958d6ec2fc0af19a5cb16fff34f8b131b71b33d45f
ToppCellmegakaryocytic-CD34+_Megakaryoblast|World / Lineage and Cell class

EFHC2 KALRN ITGA2 ITGA2B STAC

3.97e-051908951d19b2bd55789bf13e1386332f46c605973d6f8e
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

HMCN1 KALRN MICAL3 PKHD1L1 TNXB

3.97e-051908956e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 PKHD1L1 HYAL2 IL6ST CEMIP2

3.97e-051908956f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

KALRN CARD10 MICAL3 PKHD1L1 TNXB

3.97e-0519089591bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EFHC2 KALRN ITGA2B PKHD1L1 STAC

3.97e-0519089564060e4b56ac9989e659c2d5d2a6b6edeba4d8d4
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN1 SLFN5 HYAL2 IL6ST CEMIP2

3.97e-051908959b0ad888eb20acc011904d8593bc32bdef18d050
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 SLFN5 HYAL2 IL6ST CEMIP2

4.07e-051918959fc674a58f20b47255e4457d5195c8cff17b0414
ToppCell10x5'v1-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EFHC2 KALRN ITGA2B PKHD1L1 STAC

4.07e-051918957edc22e7e70697fb22690699efb352577162709b
ToppCelldroplet-Lung-LUNG-1m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 SLFN5 HYAL2 IL6ST CEMIP2

4.07e-05191895c379a499dabf3c9ed80f47adbb2d949821c5b053
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KALRN CARD10 PKHD1L1 TNXB HYAL2

4.17e-05192895291df12b4b5ff11fbaa43033692b8f4b5cdf65a1
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC BMP1 DPT TNXB CFB

4.17e-05192895a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KALRN CARD10 PKHD1L1 TNXB HYAL2

4.17e-0519289535ffe7aa9ffab85eac3326651e901c39d0119650
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC BMP1 DPT TNXB CFB

4.17e-05192895eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN1 SLFN5 HYAL2 IL6ST CEMIP2

4.17e-05192895c157981b9a179925edcaabc0cb3b8805f0929004
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R FCGBP CCR7 SLFN5 IL6ST

4.27e-0519389595f5611dd9583f339b7c9f52bb478af204fb89ad
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KALRN CARD10 PKHD1L1 TNXB HYAL2

4.27e-05193895040f6bb42aa41d0921371fdda1cc0912c4fe1930
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KALRN CARD10 PKHD1L1 TNXB HYAL2

4.27e-05193895e468287c8b30c56d1de65e8347ade233ba6cf584
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tnaive/CM_CD4|GI_small-bowel / Manually curated celltypes from each tissue

IGF1R RASA3 CDHR3 CCR7 IL6ST

4.27e-05193895772e0370bda4bffed7798b8714e32c9e2a1d9b67
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BOC KALRN PKHD1L1 TNXB HYAL2

4.38e-05194895cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 CARD10 HYAL2 IL6ST CEMIP2

4.49e-0519589512ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 PKHD1L1 HYAL2 IL6ST CEMIP2

4.49e-05195895df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 PKHD1L1 HYAL2 IL6ST CEMIP2

4.60e-051968957d5eaed189aa6116f3799be010139fb675ec65e0
ToppCellwk_15-18-Endothelial-Lymph_endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PRR5L CARD10 PKHD1L1 TNXB HYAL2

4.60e-05196895ff627244d7f5fd6a2ec009dae32d3509f0e2d95e
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP1 DPT BMPR1A SH3D19 TNXB

4.60e-051968952029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 PKHD1L1 HYAL2 IL6ST CEMIP2

4.60e-05196895dbf154b3d166ffd07be717dac8d8a3350ac63e16
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PKHD1L1 TNXB LEPR HYAL2 IL6ST

4.71e-051978950542badae77d2f606c13cfaf361319495c354351
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PKHD1L1 TNXB LEPR HYAL2 IL6ST

4.71e-05197895a6a64581699cfcb9607b288976fa3b09648725b7
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

BMP1 LRRK2 ITGA2 ACSL5 MYO5C

4.83e-05198895285f729140b1df029c24f6ca1d2438470ac51794
ToppCellCaecum-(1)_T_cell-(14)_Tcm|Caecum / shred on region, Cell_type, and subtype

IGF1R RASA3 CCR7 SLFN5 IL6ST

4.94e-051998950f89426e8dec0cbe78f6c55caaa196daf0eaf66a
ToppCellCaecum-T_cell-Tcm|Caecum / Region, Cell class and subclass

IGF1R RASA3 CCR7 SLFN5 IL6ST

4.94e-05199895cab97db995a7d7df3b8f0511139ef0fe65ee55b9
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

DPT HMCN1 SH3D19 TNXB IL6ST

4.94e-05199895b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCell(5)_Fibroblast-F|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

BOC DPT TNXB LEPR CFB

4.94e-051998951f66db4f502de4a5159cde90fcb3befb26b8d375
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_adventitial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

BOC DPT TNXB LEPR CFB

5.06e-05200895fc3c4778841c4b8bac0afb458352614b2c460617
ToppCellBronchial-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KALRN CARD10 PKHD1L1 TNXB HYAL2

5.06e-05200895c59f262b2b0a7e7dcb2940d1e466f98db6c56625
ToppCelldistal-3-Endothelial-Vein|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ELFN1 PKHD1L1 LEPR HYAL2 IL6ST

5.06e-052008953a5c85bad2e7a9ecf55d90acb04178a343b3f5fd
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BOC DPT HMCN1 TNXB LEPR

5.06e-0520089544317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

BOC DPT SH3D19 TNXB LEPR

5.06e-05200895ef30f9b68bfdb8d947ed399603e4dd0d5ff0144d
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BOC DPT SH3D19 TNXB LEPR

5.06e-05200895b28bfe6eb96b4db9cb27f0fc8fc39259c125f05e
ToppCellBronchial-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KALRN CARD10 PKHD1L1 TNXB HYAL2

5.06e-05200895e50ef394e3284a8323bfd60575b262b2be422aea
ToppCelldistal-Endothelial-Vein|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHSY1 PKHD1L1 LEPR HYAL2 IL6ST

5.06e-052008956acf7afe122f81a95c4c66f4d0878d997b57127a
ToppCellcellseq2-Mesenchymal-Fibroblastic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BOC DPT HMCN1 TNXB LEPR

5.06e-052008951c10597edd532bf172ca09870a937d35e2585081
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BOC DPT HMCN1 TNXB LEPR

5.06e-05200895440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

BOC DPT SH3D19 TNXB LEPR

5.06e-0520089587953ea65ff2a01485e13dd49d993ae6ae679cbf
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Hippocampus / BrainAtlas - Mouse McCarroll V32

LRRC19 MMEL1 GABRQ MYO5C

7.81e-051138946f270b7e59c18243e876311df721e948ce21e850
ToppCellControl-B_naive-4|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FCGBP PIWIL4 SMIM35 LEPR

8.65e-0511689435d471c8dbf408d0be3837c428d9c2a73c805a6f
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tfh|GI_small-bowel / Manually curated celltypes from each tissue

EFHC2 GLB1L3 APOF CCR7

1.19e-04126894d0d3e25e4fb074a76313fc90d8c3828b1d8ea486
Diseasequinate measurement

LRRK2 ITGA2 LEPR CFB

8.96e-0815864EFO_0021167
DiseaseGlanzmann's thrombasthenia (is_implicated_in)

ITGA2 ITGA2B

2.51e-053862DOID:2219 (is_implicated_in)
Diseasevon Willebrand's disease 1 (is_implicated_in)

ITGA2 ITGA2B

5.02e-054862DOID:0060573 (is_implicated_in)
DiseaseIgA glomerulonephritis (is_implicated_in)

IGF1R TLR9 CFB

9.17e-0530863DOID:2986 (is_implicated_in)
DiseaseNeonatal Alloimmune Thrombocytopenia

ITGA2 ITGA2B

1.25e-046862C3853779
DiseaseFNAITP

ITGA2 ITGA2B

1.25e-046862C3854603
Diseaseretinitis pigmentosa (is_implicated_in)

PRPF8 USH2A CNGA1

2.35e-0441863DOID:10584 (is_implicated_in)
Diseasetheophylline measurement

LRRK2 ITGA2

3.72e-0410862EFO_0021180
DiseaseCannabis use

IPO8 AP2A2

9.81e-0416862EFO_0007585
DiseaseParkinson's disease (is_marker_for)

ERBB2 IGF1R LRRK2

1.00e-0367863DOID:14330 (is_marker_for)
Diseaselupus nephritis (is_marker_for)

TLR9 CFB

1.11e-0317862DOID:0080162 (is_marker_for)
DiseaseAstrocytosis

ITGA2 LEPR

1.11e-0317862C3887640
DiseaseGliosis

ITGA2 LEPR

1.11e-0317862C0017639
DiseaseAge-related macular degeneration

HMCN1 CFB

1.25e-0318862cv:C0242383
Diseaselupus nephritis (is_implicated_in)

TLR9 ITGAM

1.25e-0318862DOID:0080162 (is_implicated_in)
Diseasesinusitis (is_marker_for)

TLR9 CFB

1.25e-0318862DOID:0050127 (is_marker_for)
DiseaseRetinitis pigmentosa

PRPF8 USH2A CNGA1

1.33e-0374863cv:C0035334
Diseaseasthma

DPT ERBB2 PRR5L AP2A2 CDHR3 SH3D19 CCR7 STAC

1.57e-03751868MONDO_0004979
Diseasesevere acute respiratory syndrome, COVID-19

DPT PRR5L CATSPERD USP9X SLFN5 ACSF2

1.98e-03447866EFO_0000694, MONDO_0100096
DiseaseAutism Spectrum Disorders

DPP10 GABRQ USH2A

1.99e-0385863C1510586
DiseaseOvarian Serous Adenocarcinoma

TRPM7 LRRK2

2.04e-0323862C1335177
Diseaseprimary biliary cholangitis (is_marker_for)

TLR9 LEPR

2.41e-0325862DOID:12236 (is_marker_for)
DiseaseEndogenous Hyperinsulinism

ITGAM LEPR

2.61e-0326862C1257963
DiseaseExogenous Hyperinsulinism

ITGAM LEPR

2.61e-0326862C1257964
DiseaseCompensatory Hyperinsulinemia

ITGAM LEPR

2.61e-0326862C1257965
Diseasethrombocytopenia (is_implicated_in)

ITGA2 ITGA2B

2.81e-0327862DOID:1588 (is_implicated_in)
Diseaseretinitis pigmentosa (implicated_via_orthology)

PRPF8 USH2A

2.81e-0327862DOID:10584 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
QGYVLIAHNQVRQVP

ERBB2

81

P04626
GTVPNYQRAQQLLEV

CARD10

761

Q9BWT7
GQFNLQVLQLGYNRL

ELFN1

106

P0C7U0
VQYQILGGRTANQII

CATSPERD

666

Q86XM0
LYRQGGVNATQVLIQ

APOF

111

Q13790
QLPYNGVVLAQTVAN

CCR7

276

P32248
QAGIILVSVNPAYQA

ACSF2

146

Q96CM8
FSYQCPQGQVIVAVR

DPT

46

Q07507
IVRENIQPGQEYNFL

BMP1

236

P13497
GVQGQQLIYIFENNI

DPP10

186

Q8N608
VLNIQFRYGGTFQNV

AP2A2

801

O94973
FQVIQPERALYIQAN

RASA3

646

Q14644
HRLFQQVPYQFCNVV

PARP9

701

Q8IXQ6
YVFGVGPLVNQVNIN

CFB

426

P00751
PNEGFVNQNITIFYR

HYAL2

66

Q12891
YPNINVNFLRPSQVR

MICAL3

471

Q7RTP6
FQGRPQHTQVYQKEQ

NEIL2

276

Q969S2
INVSPGYQLVRNREQ

FLACC1

81

Q96Q35
NRLYDVRIQNNPFGI

MGAM2

1036

Q2M2H8
TQYLPFIRGQENNVF

MGAM2

1281

Q2M2H8
YPQQAIVFAQVSGER

APOO

151

Q9BUR5
QVANFNIPAYDQGLL

HIPK1

61

Q86Z02
RYQQVVVGNVQDGLI

GABRQ

376

Q9UN88
LQYRQAGPVIAVQVE

GLB1L3

211

Q8NCI6
VNINPYVAVQVGGQR

FER1L4

41

A9Z1Z3
QPYQGLSNEQVLRFV

IGF1R

1211

P08069
GVTVNVNGYLFRLLN

EFHC2

511

Q5JST6
NRLGYNPNRVFFLNV

AK8

366

Q96MA6
IPNVKSYIVNRVNQG

KALRN

2971

O60229
PEVARGNVIYNQQAD

LRRK2

2041

Q5S007
PVFPENNLQFQIRYG

LEPR

561

P48357
QGNPQKVFAYINISV

NOL8

46

Q76FK4
VNAFYSPNRNQIVFP

MMEL1

571

Q495T6
VGLIQYANNPRVVFN

ITGA2

211

P17301
IFNLNVYVTPTIRGN

HMCN1

3331

Q96RW7
QAIFYPVQGQELTIR

PRR5L

141

Q6MZQ0
AYNNAGLVPLANVIA

PROSER1

216

Q86XN7
QLPVDVQNGFIRNYT

IL6ST

541

P40189
NQGIAVLNNFVYLIG

KLHL22

341

Q53GT1
GQPGAAVILYNVQVF

BOC

306

Q9BWV1
NQNRGNPAVSYVRVV

FCGBP

1721

Q9Y6R7
PYGGQENRIQITFIV

CDHR3

321

Q6ZTQ4
LFIYGGPQVQLVNNR

DPP8

666

Q6V1X1
LGAYLFIISRVQGQN

BMPR1A

11

P36894
NRFAVPTYAAKQPQQ

ADAM9

771

Q13443
IYNRSQPVLQIFVHG

ACSL5

561

Q9ULC5
YQNQPINNGEFDIIV

AREL1

261

O15033
VLRGINQKAAFPQYQ

CEMIP2

1021

Q9UHN6
NTYQVVQFNRLPLVV

LAMTOR3

76

Q9UHA4
YRNAVQQEDLFQQPG

INPP5B

841

P32019
LYQNVFACVRQPSQG

MTHFD1

401

P11586
QAQVAFQVCVRPGSY

NEURL4

1506

Q96JN8
RNSIYVIQQGAFLGL

LRRC19

106

Q9H756
RVLQQAFNYLNQGVV

IPO8

321

O15397
QGIQHRVQARPFLFQ

TSGA10IP

456

Q3SY00
PFTQYEIRIQACQNG

USH2A

3836

O75445
IYTNLGPRLQVNQVV

USP9X

796

Q93008
NCRNQIGIFPANYVK

SH3D19

536

Q5HYK7
YRDVPQPLFNSAVNQ

SEC24A

231

O95486
LAPYVNQVNLIRAGV

PNLDC1

391

Q8NA58
QENPAAFVRAIQQYV

PIWIL4

526

Q7Z3Z4
EGPNFVFNLYQIRNL

SMIM35

41

A0A1B0GVV1
YGANQVAVYRAQPVV

ITGA2B

471

P08514
PQEIVAANQRGSLYQ

ITGAM

51

P11215
GIQRILAPNSNYQDV

SWT1

811

Q5T5J6
ANTVLGQQIYFPIIF

CHSY1

646

Q86X52
EQYLPGAIALFNVNN

CNGA1

76

P29973
TINRANVYVGFQVQL

PRPF8

1541

Q6P2Q9
YPRRSQQQQVPVVDF

SNURF

41

Q9Y675
VRAANGAQYIFQPQQ

GTF2A1

166

P52655
YAEVQRAVLFPFQQA

RNF212

256

Q495C1
AYQFVRDPQSGQLVV

TNRC18

846

O15417
QENRVQKGNGYFQVP

WDR48

496

Q8TAF3
NFINQAQLGIFRAFP

TLR9

401

Q9NR96
QQAIFVGQNYPTRIR

SPATA31D1

1476

Q6ZQQ2
IGFFPANFVQRLQQN

STAC

331

Q99469
SFLVQYRDAQGQPQA

TNXB

3291

P22105
DPRYAVTFLNLGQIQ

PKHD1L1

3316

Q86WI1
PQCYQRVQQLQGVYS

SLC30A7

306

Q8NEW0
FNIPLHQINQVYRQG

UBP1

486

Q9NZI7
TQFPGREQQVRLIYQ

TMUB1

131

Q9BVT8
IQYVQRPLGQVGVFL

TRIM64

396

A6NGJ6
PDNINEGQVQVRTLY

PTGR2

31

Q8N8N7
QAAVNAIQIFGNLLY

ZNF106

1531

Q9H2Y7
VVRNAGPIANYLQQV

SLFN5

711

Q08AF3
LLDFLAVNQQAGPYV

TRPM7

976

Q96QT4
LQRQQQLFGVDYRPV

HECTD3

161

Q5T447
FVQQYAFVRPVILQG

JMJD8

56

Q96S16
RAALIIQQYFRGQQT

MYO5C

781

Q9NQX4
QNQLLSRGFENLVPY

NUP62CL

46

Q9H1M0