Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

4.67e-1335738GO:0015020
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

PRLHR ADRA1D GPR21 GPR65 P2RY12 ADGRG2 CXCR6 PTPRR GPR35 GLP1R UNC5C SCN7A S1PR2 LPAR2 CCR7 TAS2R40 TNFRSF10B IL1R1 S1PR1 GPR132 LPAR1 OR14A16 OPRD1

2.29e-1013537323GO:0004888
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

6.84e-1028736GO:0001972
GeneOntologyMolecularFunctionG protein-coupled receptor activity

PRLHR ADRA1D GPR21 GPR65 P2RY12 ADGRG2 CXCR6 GPR35 GLP1R S1PR2 LPAR2 CCR7 TAS2R40 S1PR1 GPR132 LPAR1 OR14A16 OPRD1

1.98e-098847318GO:0004930
GeneOntologyMolecularFunctionretinoid binding

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

2.10e-0848736GO:0005501
GeneOntologyMolecularFunctionisoprenoid binding

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

2.39e-0849736GO:0019840
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT1A4 UGT1A3 UGT1A5 DPY19L4 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.49e-08211739GO:0016758
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

8.72e-08153738GO:0008194
GeneOntologyMolecularFunctionbioactive lipid receptor activity

S1PR2 LPAR2 S1PR1 LPAR1

2.89e-0716734GO:0045125
GeneOntologyMolecularFunctionglycosyltransferase activity

UGT1A4 UGT1A3 UGT1A5 DPY19L4 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.03e-06288739GO:0016757
GeneOntologyMolecularFunctioncarboxylic acid binding

UGT1A4 UGT1A3 SIGLEC9 UGT1A5 FURIN UGT2B4 UGT2B7 UGT2B15

2.58e-06239738GO:0031406
GeneOntologyMolecularFunctionmonocarboxylic acid binding

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

2.61e-06107736GO:0033293
GeneOntologyMolecularFunctionorganic acid binding

UGT1A4 UGT1A3 SIGLEC9 UGT1A5 FURIN UGT2B4 UGT2B7 UGT2B15

4.04e-06254738GO:0043177
GeneOntologyMolecularFunctionG protein-coupled chemoattractant receptor activity

CXCR6 GPR35 CCR7

1.15e-0426733GO:0001637
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A SCN7A SCN9A

1.15e-0426733GO:0005248
GeneOntologyMolecularFunctionchemokine receptor activity

CXCR6 GPR35 CCR7

1.15e-0426733GO:0004950
GeneOntologyMolecularFunctionlysophosphatidic acid receptor activity

LPAR2 LPAR1

1.31e-045732GO:0070915
GeneOntologyMolecularFunctionlipid binding

UGT1A4 UGT1A3 GPR155 UGT1A5 NPC1L1 UGT2B4 UGT2B7 UGT2B15 S1PR2 LPAR2 S1PR1 LPAR1

2.27e-049887312GO:0008289
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SCN11A SLC9A8 SLC4A7 KCNA10 SCN7A SCN9A KCNMB4 ATP2B2

2.91e-04465738GO:0046873
GeneOntologyMolecularFunctionsphingosine-1-phosphate receptor activity

S1PR2 S1PR1

3.64e-048732GO:0038036
GeneOntologyMolecularFunctionC-X-C chemokine receptor activity

CXCR6 GPR35

3.64e-048732GO:0016494
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN11A SLC9A8 SLC4A7 SCN7A SCN9A

4.08e-04171735GO:0015081
GeneOntologyMolecularFunctioncytokine receptor activity

CXCR6 GPR35 CCR7 IL1R1

4.41e-0497734GO:0004896
GeneOntologyMolecularFunctionsodium channel activity

SCN11A SCN7A SCN9A

9.11e-0452733GO:0005272
GeneOntologyMolecularFunctionPDZ domain binding

CFTR LPAR2 ATP2B2 LPAR1

1.07e-03123734GO:0030165
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

PRLHR GLP1R S1PR2 OPRD1

1.44e-03133734GO:0008528
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SCN11A SLC9A8 SLC4A7 KCNA10 CFTR SCN7A SCN9A KCNMB4 ATP2B2

1.73e-03758739GO:0015318
GeneOntologyMolecularFunctionpeptide receptor activity

PRLHR GLP1R S1PR2 OPRD1

1.73e-03140734GO:0001653
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SCN11A SLC9A8 SLC4A7 KCNA10 SCN7A SCN9A KCNMB4 ATP2B2

2.02e-03627738GO:0022890
GeneOntologyMolecularFunctiontransporter activity

SCN11A SLC9A8 SLC4A7 KCNA10 CFTR NPC1L1 SCN7A SCN9A ATP11C KCNMB4 ATP2B2 SLC35A5

2.34e-0312897312GO:0005215
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SCN11A SLC9A8 SLC4A7 KCNA10 CFTR SCN7A SCN9A KCNMB4 ATP2B2

2.34e-03793739GO:0015075
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SCN11A SLC9A8 SLC4A7 KCNA10 SCN7A SCN9A KCNMB4 ATP2B2

2.87e-03664738GO:0008324
GeneOntologyMolecularFunctionimmune receptor activity

CXCR6 GPR35 CCR7 IL1R1

3.14e-03165734GO:0140375
GeneOntologyMolecularFunctionC-C chemokine receptor activity

CXCR6 CCR7

3.17e-0323732GO:0016493
GeneOntologyMolecularFunctionC-C chemokine binding

CXCR6 CCR7

3.45e-0324732GO:0019957
GeneOntologyMolecularFunctionprotease binding

FURIN TNFRSF10B IL1R1 RNF139

4.37e-03181734GO:0002020
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A7 CFTR

6.09e-0332732GO:0015106
GeneOntologyMolecularFunctionchemokine binding

CXCR6 CCR7

6.47e-0333732GO:0019956
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

KCNA10 CFTR

6.47e-0333732GO:0005217
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SCN11A KCNA10 CFTR SCN7A SCN9A KCNMB4

6.64e-03459736GO:0005216
GeneOntologyMolecularFunctionneuropeptide binding

PRLHR OPRD1

8.08e-0337732GO:0042923
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SCN11A KCNA10 SCN7A SCN9A KCNMB4

8.41e-03343735GO:0005261
GeneOntologyBiologicalProcesscellular glucuronidation

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

3.25e-1521738GO:0052695
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.46e-1426738GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.46e-1426738GO:0006063
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT1A3 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.45e-1212736GO:0052697
GeneOntologyBiologicalProcessbiphenyl catabolic process

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.68e-118735GO:0070980
GeneOntologyBiologicalProcessbiphenyl metabolic process

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.20e-1010735GO:0018879
GeneOntologyBiologicalProcessadenylate cyclase-activating G protein-coupled receptor signaling pathway

ADRA1D GPR65 ADGRG2 GLP1R S1PR2 LPAR2 S1PR1 LPAR1 ADCY5 OPRD1

1.37e-091917310GO:0007189
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

ADRA1D GPR65 P2RY12 ADGRG2 GLP1R S1PR2 LPAR2 S1PR1 LPAR1 ADCY5 OPRD1

4.99e-092867311GO:0007188
GeneOntologyBiologicalProcessestrogen metabolic process

UGT1A3 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.85e-0852736GO:0008210
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

SCN11A PRLHR ADRA1D GPR21 GPR65 P2RY12 ADGRG2 CXCR6 GPR35 GLP1R S1PR2 LPAR2 CCR7 TAS2R40 S1PR1 GPR132 LPAR1 ADCY5 OR14A16 OPRD1

4.73e-0813957320GO:0007186
GeneOntologyBiologicalProcessbenzene-containing compound metabolic process

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.93e-0737735GO:0042537
GeneOntologyBiologicalProcessxenobiotic catabolic process

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.93e-0737735GO:0042178
GeneOntologyBiologicalProcessandrogen metabolic process

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.21e-0738735GO:0008209
GeneOntologyBiologicalProcesspositive regulation of cytosolic calcium ion concentration

ADRA1D CXCR6 GPR35 GLP1R LPAR2 CCR7 LPAR1 ADCY5

1.25e-06224738GO:0007204
GeneOntologyBiologicalProcessmetal ion transport

SCN11A SLC9A8 SLC4A7 KCNA10 P2RY12 GPR35 GLP1R CFTR SCN7A SCN9A TMEM163 KCNMB4 CCR7 ATP2B2 OPRD1

1.79e-0610007315GO:0030001
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SCN11A SLC9A8 SLC4A7 KCNA10 P2RY12 GPR35 GLP1R CFTR SCN7A SCN9A TMEM163 KCNMB4 CCR7 ATP2B2

3.64e-069227314GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SCN11A SLC9A8 SLC4A7 KCNA10 P2RY12 GPR35 GLP1R CFTR SCN7A SCN9A TMEM163 KCNMB4 CCR7 ATP2B2

4.66e-069427314GO:0098655
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SCN11A SLC9A8 SLC4A7 KCNA10 P2RY12 GPR35 GLP1R CFTR SCN7A SCN9A ATP11C TMEM163 KCNMB4 CCR7 ATP2B2

6.77e-0611157315GO:0034220
GeneOntologyBiologicalProcesssteroid metabolic process

UGT1A4 UGT1A3 CFTR NPC1L1 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.01e-06376739GO:0008202
GeneOntologyBiologicalProcesshormone metabolic process

UGT1A3 PRLHR FURIN UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.63e-06286738GO:0042445
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled receptor signaling pathway

ADRA1D GPR65 P2RY12 GPR35 S1PR1 OPRD1

7.67e-06133736GO:0007200
GeneOntologyBiologicalProcessmonoatomic cation transport

SCN11A SLC9A8 SLC4A7 KCNA10 P2RY12 GPR35 GLP1R CFTR SCN7A SCN9A TMEM163 KCNMB4 CCR7 ATP2B2 OPRD1

1.05e-0511577315GO:0006812
GeneOntologyBiologicalProcessxenobiotic metabolic process

UGT1A3 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.07e-05141736GO:0006805
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SCN11A SLC9A8 SLC4A7 KCNA10 P2RY12 GPR35 GLP1R CFTR SCN7A SCN9A TMEM163 KCNMB4 CCR7 ATP2B2

1.11e-0510177314GO:0098660
GeneOntologyBiologicalProcesspositive regulation of Rho protein signal transduction

GPR65 GPR35 LPAR2 LPAR1

1.32e-0541734GO:0035025
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

P2RY12 S1PR1 LPAR1 ADCY5 OPRD1

1.35e-0586735GO:0007193
GeneOntologyBiologicalProcessmonoatomic ion transport

SCN11A SLC9A8 SLC4A7 KCNA10 P2RY12 GPR35 GLP1R CFTR SCN7A SCN9A ATP11C TMEM163 KCNMB4 CCR7 ATP2B2 OPRD1

1.94e-0513747316GO:0006811
GeneOntologyBiologicalProcessregulation of hormone levels

UGT1A3 PRLHR GLP1R FURIN CFTR UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11 ADCY5

2.70e-056847311GO:0010817
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN11A GPR35 SCN9A KCNMB4 S1PR1

4.83e-05112735GO:0019226
GeneOntologyBiologicalProcessneuronal action potential

SCN11A GPR35 SCN9A KCNMB4

7.34e-0563734GO:0019228
GeneOntologyBiologicalProcessaction potential

SCN11A KCNA10 GPR35 SCN7A SCN9A KCNMB4

7.86e-05201736GO:0001508
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN11A SLC9A8 SLC4A7 CFTR SCN7A SCN9A

9.49e-05208736GO:0035725
GeneOntologyBiologicalProcessbehavioral response to chemical pain

SCN11A SCN9A

1.23e-045732GO:0061366
GeneOntologyBiologicalProcessbehavioral response to formalin induced pain

SCN11A SCN9A

1.23e-045732GO:0061368
GeneOntologyBiologicalProcesscellular response to xenobiotic stimulus

UGT1A3 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.36e-04222736GO:0071466
GeneOntologyBiologicalProcessregulation of membrane potential

SCN11A KCNA10 GPR35 CFTR SCN7A SCN9A S1PR2 KCNMB4 OPRD1

1.54e-04559739GO:0042391
GeneOntologyBiologicalProcesspositive regulation of small GTPase mediated signal transduction

GPR65 GPR35 LPAR2 LPAR1

3.19e-0492734GO:0051057
GeneOntologyBiologicalProcessregulation of Rho protein signal transduction

GPR65 GPR35 LPAR2 LPAR1

4.06e-0498734GO:0035023
GeneOntologyBiologicalProcesssodium ion transport

SCN11A SLC9A8 SLC4A7 CFTR SCN7A SCN9A

4.29e-04275736GO:0006814
GeneOntologyBiologicalProcessvitamin D3 metabolic process

UGT1A4 UGT1A3

4.38e-049732GO:0070640
GeneOntologyBiologicalProcesschemotaxis

CMTM1 P2RY12 CXCR6 GPR35 UNC5C CCR7 S1PR1 LPAR1

4.75e-04517738GO:0006935
GeneOntologyBiologicalProcesstaxis

CMTM1 P2RY12 CXCR6 GPR35 UNC5C CCR7 S1PR1 LPAR1

4.88e-04519738GO:0042330
GeneOntologyBiologicalProcessresponse to xenobiotic stimulus

UGT1A3 SCN11A CFTR UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.26e-04525738GO:0009410
GeneOntologyBiologicalProcessnegative regulation of action potential

GPR35 SCN9A

5.46e-0410732GO:0045759
GeneOntologyBiologicalProcessheart contraction

SCN11A ADRA1D GLP1R SCN7A SCN9A ATP2B2

6.54e-04298736GO:0060047
GeneOntologyBiologicalProcessfat-soluble vitamin metabolic process

UGT1A4 UGT1A3 NPC1L1

7.84e-0451733GO:0006775
GeneOntologyBiologicalProcessheart process

SCN11A ADRA1D GLP1R SCN7A SCN9A ATP2B2

7.90e-04309736GO:0003015
GeneOntologyBiologicalProcessG protein-coupled purinergic receptor signaling pathway

P2RY12 ADCY5

9.40e-0413732GO:0035588
GeneOntologyBiologicalProcessadenylate cyclase-activating dopamine receptor signaling pathway

ADCY5 OPRD1

9.40e-0413732GO:0007191
GeneOntologyBiologicalProcessG protein-coupled adenosine receptor signaling pathway

P2RY12 ADCY5

9.40e-0413732GO:0001973
GeneOntologyBiologicalProcessmonocarboxylic acid metabolic process

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11 EIF2AK3

1.07e-03731739GO:0032787
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception

SCN11A SCN9A ATP2B2

1.09e-0357733GO:0050974
GeneOntologyBiologicalProcesssphingosine-1-phosphate receptor signaling pathway

S1PR2 S1PR1

1.26e-0315732GO:0003376
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN11A SCN7A SCN9A

1.38e-0362733GO:0086002
GeneOntologyCellularComponentnuclear outer membrane

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.70e-0740735GO:0005640
GeneOntologyCellularComponentcell surface

P2RY12 ADGRG2 CXCR6 SIGLEC9 FURIN CFTR UNC5C LPAR2 CCR7 TNFRSF10B IL1R1 S1PR1 LPAR1 CLEC2B

2.58e-0511117314GO:0009986
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN11A SCN7A SCN9A

2.68e-0517733GO:0001518
GeneOntologyCellularComponentnuclear membrane

TMEM176B SHISA5 DPY19L4 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.91e-05349738GO:0031965
GeneOntologyCellularComponentendoplasmic reticulum membrane

UGT1A4 UGT1A3 SHISA5 UGT1A5 FURIN CFTR VPS13A UGT2B4 UGT2B7 UGT2B15 ATP11C UGT2B28 UGT2B11 RNF139 EIF2AK3

3.33e-0512937315GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

UGT1A4 UGT1A3 SHISA5 UGT1A5 FURIN CFTR VPS13A UGT2B4 UGT2B7 UGT2B15 ATP11C UGT2B28 UGT2B11 RNF139 EIF2AK3

3.51e-0512997315GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

UGT1A4 UGT1A3 SHISA5 UGT1A5 FURIN CFTR VPS13A UGT2B4 UGT2B7 UGT2B15 ATP11C UGT2B28 UGT2B11 RNF139 EIF2AK3

4.49e-0513277315GO:0042175
GeneOntologyCellularComponentsodium channel complex

SCN11A SCN7A SCN9A

1.40e-0429733GO:0034706
GeneOntologyCellularComponentorganelle outer membrane

VPS13A UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

4.31e-04279736GO:0031968
GeneOntologyCellularComponentouter membrane

VPS13A UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

4.48e-04281736GO:0019867
GeneOntologyCellularComponentnuclear envelope

TMEM176B SHISA5 DPY19L4 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.35e-04560738GO:0005635
GeneOntologyCellularComponentlysosomal membrane

GPR155 TBC1D7 CFTR VPS13A ATP11C TMEM163 MEAK7

1.14e-03462737GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

GPR155 TBC1D7 CFTR VPS13A ATP11C TMEM163 MEAK7

1.14e-03462737GO:0098852
GeneOntologyCellularComponentcation channel complex

SCN11A KCNA10 SCN7A SCN9A KCNMB4

1.39e-03235735GO:0034703
GeneOntologyCellularComponentvacuolar membrane

GPR155 TBC1D7 CFTR VPS13A ATP11C TMEM163 MEAK7

1.94e-03507737GO:0005774
GeneOntologyCellularComponentmonoatomic ion channel complex

SCN11A KCNA10 CFTR SCN7A SCN9A KCNMB4

2.06e-03378736GO:0034702
GeneOntologyCellularComponentexternal side of plasma membrane

P2RY12 CXCR6 SIGLEC9 CCR7 IL1R1 S1PR1 CLEC2B

2.21e-03519737GO:0009897
GeneOntologyCellularComponentpresynaptic membrane

SCN11A LPAR2 ATP2B2 LPAR1 OPRD1

2.84e-03277735GO:0042734
GeneOntologyCellularComponenttransporter complex

SCN11A KCNA10 CFTR SCN7A SCN9A ATP11C KCNMB4

3.06e-03550737GO:1990351
DomainUDPGT

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.68e-1521718PS00375
DomainUDPGT

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.68e-1521718PF00201
DomainUDP_glucos_trans

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.68e-1521718IPR002213
DomainGPCR_Rhodpsn_7TM

PRLHR ADRA1D GPR21 GPR65 P2RY12 CXCR6 GPR35 S1PR2 LPAR2 CCR7 S1PR1 GPR132 LPAR1 OR14A16 OPRD1

2.54e-086707115IPR017452
Domain7tm_1

PRLHR ADRA1D GPR21 GPR65 P2RY12 CXCR6 GPR35 S1PR2 LPAR2 CCR7 S1PR1 GPR132 LPAR1 OR14A16 OPRD1

2.92e-086777115PF00001
DomainG_PROTEIN_RECEP_F1_1

PRLHR ADRA1D GPR21 GPR65 P2RY12 CXCR6 GPR35 S1PR2 LPAR2 CCR7 S1PR1 GPR132 LPAR1 OR14A16 OPRD1

3.40e-086857115PS00237
DomainG_PROTEIN_RECEP_F1_2

PRLHR ADRA1D GPR21 GPR65 P2RY12 CXCR6 GPR35 S1PR2 LPAR2 CCR7 S1PR1 GPR132 LPAR1 OR14A16 OPRD1

3.82e-086917115PS50262
DomainGPCR_Rhodpsn

PRLHR ADRA1D GPR21 GPR65 P2RY12 CXCR6 GPR35 S1PR2 LPAR2 CCR7 S1PR1 GPR132 LPAR1 OR14A16 OPRD1

3.89e-086927115IPR000276
Domain7TM_GPCR_Srsx

PRLHR ADRA1D S1PR2 LPAR2 S1PR1 LPAR1 OPRD1

2.24e-07112717SM01381
DomainNa_channel_asu

SCN11A SCN7A SCN9A

6.20e-0610713IPR001696
DomainNa_trans_assoc

SCN11A SCN7A SCN9A

6.20e-0610713IPR010526
DomainNa_trans_assoc

SCN11A SCN7A SCN9A

6.20e-0610713PF06512
DomainLPA_rcpt_EDG2

S1PR1 LPAR1

1.42e-052712IPR002277
DomainLPA_rcpt

LPAR2 LPAR1

4.26e-053712IPR004065
DomainChannel_four-helix_dom

SCN11A KCNA10 SCN7A SCN9A

6.50e-0557714IPR027359
Domain-

SCN11A KCNA10 SCN7A SCN9A

6.50e-05577141.20.120.350
DomainS1P_rcpt

S1PR2 S1PR1

1.41e-045712IPR004061
DomainIon_trans_dom

SCN11A KCNA10 SCN7A SCN9A

9.34e-04114714IPR005821
DomainIon_trans

SCN11A KCNA10 SCN7A SCN9A

9.34e-04114714PF00520
DomainChemokine_rcpt

CXCR6 CCR7

1.65e-0316712IPR000355
DomainDEATH

UNC5C TNFRSF10B

4.70e-0327712SM00005
Domain-

ATP11C ATP2B2

6.57e-03327122.70.150.10
Domain-

ATP11C ATP2B2

6.57e-03327123.40.1110.10
DomainDeath

UNC5C TNFRSF10B

6.97e-0333712PF00531
DomainGPCR_2_secretin-like_CS

ADGRG2 GLP1R

7.39e-0334712IPR017983
DomainATPase_P-typ_cyto_domN

ATP11C ATP2B2

7.82e-0335712IPR023299
DomainATPase_P-typ_P_site

ATP11C ATP2B2

8.26e-0336712IPR018303
DomainP_typ_ATPase

ATP11C ATP2B2

8.26e-0336712IPR001757
DomainATPASE_E1_E2

ATP11C ATP2B2

8.26e-0336712PS00154
DomainCadherin_tail

PCDHGA11 PCDHGA10

8.71e-0337712PF15974
DomainATPase_P-typ_transduc_dom_A

ATP11C ATP2B2

8.71e-0337712IPR008250
DomainE1-E2_ATPase

ATP11C ATP2B2

8.71e-0337712PF00122
DomainCadherin_CBD

PCDHGA11 PCDHGA10

8.71e-0337712IPR031904
DomainDeath_domain

UNC5C TNFRSF10B

9.17e-0338712IPR000488
DomainDEATH_DOMAIN

UNC5C TNFRSF10B

9.17e-0338712PS50017
DomainCadherin_C_2

PCDHGA11 PCDHGA10

1.11e-0242712PF16492
DomainCadherin_C

PCDHGA11 PCDHGA10

1.11e-0242712IPR032455
PathwayREACTOME_PREDNISONE_ADME

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.32e-1423588MM16639
PathwayREACTOME_GLUCURONIDATION

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

3.47e-1424588MM14599
PathwayREACTOME_GLUCURONIDATION

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.09e-1425588M17787
PathwayWP_GLUCURONIDATION

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.09e-1425588MM15820
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.09e-1425588M605
PathwayWP_GLUCURONIDATION

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.33e-1426588M39404
PathwayWP_GPCRS_NONODORANT

PRLHR ADRA1D GPR65 P2RY12 ADGRG2 CXCR6 GLP1R S1PR2 LPAR2 CCR7 TAS2R40 S1PR1 GPR132 LPAR1 OPRD1

1.33e-132665815MM15843
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.45e-1328588M19580
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

4.27e-1241588M7399
PathwayREACTOME_ASPIRIN_ADME

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.85e-1244588M45014
PathwayREACTOME_ASPIRIN_ADME

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

9.52e-1245588MM15694
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.76e-1151588M17726
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

3.25e-1152588M14171
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.21e-1155588M14933
PathwayREACTOME_GPCR_LIGAND_BINDING

PRLHR ADRA1D GPR65 P2RY12 CXCR6 GPR35 GLP1R S1PR2 LPAR2 CCR7 TAS2R40 S1PR1 GPR132 LPAR1 OPRD1

1.29e-104305815MM15160
PathwayKEGG_RETINOL_METABOLISM

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.84e-1064588M9488
PathwayREACTOME_GPCR_LIGAND_BINDING

PRLHR ADRA1D GPR65 P2RY12 CXCR6 GPR35 GLP1R S1PR2 LPAR2 CCR7 TAS2R40 S1PR1 GPR132 LPAR1 OPRD1

3.63e-104635815M507
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

3.85e-1070588M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

4.85e-1072588M9257
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

PRLHR ADRA1D GPR65 P2RY12 CXCR6 GPR35 S1PR2 LPAR2 CCR7 S1PR1 GPR132 LPAR1 OPRD1

6.13e-103305813M18334
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

PRLHR ADRA1D GPR65 P2RY12 CXCR6 GPR35 S1PR2 LPAR2 CCR7 S1PR1 GPR132 LPAR1 OPRD1

6.84e-103335813MM14963
PathwayREACTOME_SIGNALING_BY_GPCR

PRLHR ADRA1D GPR65 P2RY12 CXCR6 GPR35 GLP1R S1PR2 LPAR2 CCR7 TAS2R40 S1PR1 GPR132 LPAR1 ADCY5 OPRD1

4.17e-096465816MM14962
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.18e-08107588MM14595
PathwayREACTOME_SIGNALING_BY_GPCR

PRLHR ADRA1D GPR65 P2RY12 CXCR6 GPR35 GLP1R S1PR2 LPAR2 CCR7 TAS2R40 S1PR1 GPR132 LPAR1 ADCY5 OPRD1

1.36e-087025816M746
PathwayREACTOME_DRUG_ADME

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.37e-08109588M45012
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.37e-08109588M18788
PathwayREACTOME_DRUG_ADME

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.74e-08119588MM15692
PathwayREACTOME_LYSOSPHINGOLIPID_AND_LPA_RECEPTORS

S1PR2 LPAR2 S1PR1 LPAR1

2.50e-0714584M27331
PathwayREACTOME_LYSOSPHINGOLIPID_AND_LPA_RECEPTORS

S1PR2 LPAR2 S1PR1 LPAR1

2.50e-0714584MM15062
PathwayREACTOME_PARACETAMOL_ADME

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.11e-0739585MM15695
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.62e-07183588M39588
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

PRLHR ADRA1D GPR35 GLP1R S1PR2 LPAR2 S1PR1 LPAR1 OPRD1

1.51e-06272589M13380
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

P2RY12 CXCR6 S1PR2 LPAR2 CCR7 TAS2R40 LPAR1 ADCY5 OPRD1

2.49e-06289589MM15057
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.93e-06219588MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

3.04e-06220588M10320
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

P2RY12 CXCR6 S1PR2 LPAR2 CCR7 TAS2R40 LPAR1 ADCY5 OPRD1

4.91e-06314589M600
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

PRLHR ADRA1D GPR21 GPR65 P2RY12 GPR35 CCR7 OPRD1

1.04e-05260588M39397
PathwayREACTOME_ATORVASTATIN_ADME

UGT1A4 UGT1A3 UGT1A5

2.90e-0515583MM15697
PathwayWP_GPCRS_SMALL_LIGAND

S1PR2 S1PR1 LPAR1

5.16e-0518583MM15858
PathwayWP_SMALL_LIGAND_GPCRS

S1PR2 S1PR1 LPAR1

6.11e-0519583M39728
PathwayREACTOME_HEME_DEGRADATION

UGT1A4 UGT1A3 UGT1A5

7.17e-0520583MM14721
PathwayWP_TAMOXIFEN_METABOLISM

UGT1A4 UGT2B7 UGT2B15

8.34e-0521583M39631
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN11A SCN7A SCN9A

2.74e-0431583M877
PathwayREACTOME_METABOLISM_OF_PORPHYRINS

UGT1A4 UGT1A3 UGT1A5

3.01e-0432583MM14719
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN11A SCN7A SCN9A

3.01e-0432583M27455
PathwayBIOCARTA_AKAP13_PATHWAY

LPAR2 LPAR1

5.88e-049582MM1477
PathwayKEGG_MEDICUS_REFERENCE_LPA_GNAQ_11_RHOA_SIGNALING_PATHWAY

LPAR2 LPAR1

5.88e-049582M47732
PathwayWP_GPCRS_OTHER

S1PR2 CCR7 S1PR1 GPR132

6.47e-0496584MM15939
PathwayREACTOME_PREDNISONE_ADME

UGT1A3 UGT2B7

7.33e-0410582M46430
PathwayBIOCARTA_AKAP13_PATHWAY

LPAR2 LPAR1

8.93e-0411582M17668
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

ADRA1D GPR65 P2RY12 GPR35 OPRD1

9.86e-04186585MM15994
PathwayKEGG_MEDICUS_REFERENCE_LPA_GNA12_13_RHOA_SIGNALING_PATHWAY

LPAR2 LPAR1

1.26e-0313582M47731
PathwayWP_CODEINE_AND_MORPHINE_METABOLISM

UGT2B4 UGT2B7

1.47e-0314582M39328
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

ADRA1D GPR65 LPAR2 GPR132 LPAR1

1.69e-03210585MM15043
PathwayWP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE

ADRA1D ADCY5

1.92e-0316582M39849
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

ADRA1D GPR65 LPAR2 GPR132 LPAR1

1.95e-03217585M18437
PathwayREACTOME_CARDIAC_CONDUCTION

SCN11A SCN7A SCN9A ATP2B2

1.99e-03130584M27454
PathwayPID_LYSOPHOSPHOLIPID_PATHWAY

LPAR2 LPAR1 ADCY5

2.41e-0365583M15
PathwayWP_ESTROGEN_METABOLISM_WP697

UGT1A3 UGT2B7

2.44e-0318582M39424
PathwayWP_GPCRS_PEPTIDE

CXCR6 CCR7 OPRD1

2.98e-0370583MM15959
PathwayPID_S1P_META_PATHWAY

S1PR2 S1PR1

3.32e-0321582M155
PathwayWP_PEPTIDE_GPCRS

CXCR6 CCR7 OPRD1

3.62e-0375583M39696
PathwayWP_ESTROGEN_METABOLISM

UGT1A3 UGT1A5

3.65e-0322582MM15888
PathwayKEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY

LPAR2 LPAR1

3.98e-0323582M47549
PathwayWP_SIGNAL_TRANSDUCTION_OF_S1P_RECEPTOR

S1PR2 S1PR1

3.98e-0323582MM15952
PathwayWP_UNFOLDED_PROTEIN_RESPONSE

TNFRSF10B EIF2AK3

4.33e-0324582M39878
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

ADGRG2 GLP1R

4.33e-0324582M39643
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

ADGRG2 GLP1R

4.33e-0324582MM15992
PathwayWP_S1P_RECEPTOR_SIGNAL_TRANSDUCTION

S1PR2 S1PR1

4.70e-0325582M39384
Pubmed

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.42e-13773526074487
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.32e-126673819898482
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.97e-12873532093886
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT1A4 UGT1A3 UGT2B4 UGT2B7 UGT2B15

2.77e-111273520308471
Pubmed

Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis.

UGT1A4 UGT1A3 UGT2B4 UGT2B7 UGT2B15

2.77e-111273518161889
Pubmed

Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism.

UGT1A4 UGT1A3 UGT2B7 UGT2B15

1.24e-09873412695355
Pubmed

Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.

UGT1A4 UGT1A3 UGT2B7 UGT2B15

1.24e-09873422579593
Pubmed

Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine.

UGT1A3 UGT2B4 UGT2B7 UGT2B15

1.24e-09873410748067
Pubmed

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

UGT1A3 UGT2B4 UGT2B7 UGT2B15

1.24e-09873418719240
Pubmed

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

UGT1A3 UGT2B4 UGT2B7 UGT2B15

1.24e-09873420142249
Pubmed

Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis.

S1PR2 LPAR2 S1PR1 LPAR1

3.71e-091073412401212
Pubmed

Sphingosine-1-phosphate inhibits cell migration and endothelial to mesenchymal cell transformation during cardiac development.

S1PR2 LPAR2 S1PR1 LPAR1

3.71e-091073416434032
Pubmed

Dissociation of heterotrimeric g proteins in cells.

P2RY12 CXCR6 GLP1R S1PR2 CCR7 S1PR1 LPAR1 OPRD1

4.25e-0917973818577758
Pubmed

Stimulatory actions of lysophosphatidic acid on mouse ATDC5 chondroprogenitor cells.

S1PR2 LPAR2 S1PR1 LPAR1

5.83e-091173420458606
Pubmed

Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13.

UGT2B4 UGT2B7 UGT2B15

8.87e-0937337835904
Pubmed

Pharmacogenetics of UGT1A4, UGT2B7 and UGT2B15 and Their Influence on Tamoxifen Disposition in Asian Breast Cancer Patients.

UGT1A4 UGT2B7 UGT2B15

8.87e-09373327098059
Pubmed

Expression patterns of the lysophospholipid receptor genes during mouse early development.

S1PR2 LPAR2 S1PR1 LPAR1

1.26e-081373418924241
Pubmed

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

UGT1A4 UGT1A3 UGT1A5 UGT2B4

1.76e-08147349295054
Pubmed

Lysophospholipid receptor nomenclature review: IUPHAR Review 8.

S1PR2 LPAR2 S1PR1 LPAR1

2.40e-081573424602016
Pubmed

Sphingosine 1-phosphate: a ligand for the EDG-1 family of G-protein-coupled receptors.

S1PR2 LPAR2 S1PR1

3.54e-08473310818441
Pubmed

Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate.

S1PR2 S1PR1 LPAR1

3.54e-0847339931453
Pubmed

Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior.

LPAR2 S1PR1 LPAR1

3.54e-08473311087877
Pubmed

Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.

UGT1A4 UGT2B7 UGT2B15

3.54e-08473326176234
Pubmed

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.

UGT1A3 UGT2B4 UGT2B7 UGT2B15

5.34e-081873420056724
Pubmed

UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.

UGT2B4 UGT2B7 UGT2B15

8.84e-08573315318931
Pubmed

Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3.

S1PR2 S1PR1 LPAR1

1.77e-07673311443127
Pubmed

Lysophosphatidic acid 2 receptor-mediated supramolecular complex formation regulates its antiapoptotic effect.

LPAR2 S1PR1 LPAR1

3.09e-07773319293149
Pubmed

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.

UGT1A3 UGT2B4 UGT2B7

4.93e-07873318052087
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A4 UGT1A3 UGT1A5

7.38e-07973322511988
Pubmed

A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

UGT1A4 UGT1A3 UGT1A5

7.38e-0797331339448
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A4 UGT1A3 UGT1A5

1.05e-061073323642732
Pubmed

UDP-glucuronosyltransferases.

UGT1A4 UGT1A3 UGT1A5

1.05e-061073311465080
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

UGT1A4 UGT1A3 UGT1A5

1.05e-061073323371916
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A4 UGT1A3 UGT1A5

1.05e-061073322558097
Pubmed

Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development.

S1PR2 LPAR2 S1PR1 LPAR1

1.54e-064073421319224
Pubmed

Stable association between G alpha(q) and phospholipase C beta 1 in living cells.

ADRA1D GPR65 LPAR2 GPR132 LPAR1

1.77e-069573516754659
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

UGT1A4 UGT1A3 UGT1A5

1.93e-061273319419973
Pubmed

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

UGT1A4 UGT1A3 UGT1A5

1.93e-061273311434514
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A4 UGT1A3 UGT1A5

2.50e-061373322085899
Pubmed

Genome-wide analysis of hepatic lipid content in extreme obesity.

UGT1A4 UGT1A3 UGT1A5

2.50e-061373325246029
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

UGT1A4 UGT1A3 UGT1A5

3.18e-061473321646302
Pubmed

Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

UGT1A4 UGT1A3 UGT1A5

3.18e-061473310836148
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

UGT1A4 UGT1A3 UGT1A5

3.18e-061473314672974
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

ADRA1D P2RY12 CXCR6 GLP1R CCR7 OPRD1

4.14e-0620073618240029
Pubmed

Role of sphingosine-1-phosphate receptor 1 and sphingosine-1-phosphate receptor 2 in hyperglycemia-induced endothelial cell dysfunction.

S1PR2 S1PR1

4.35e-06273225673082
Pubmed

Correlation between UDP-glucuronosyltransferase genotypes and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronidation phenotype in human liver microsomes.

UGT1A4 UGT2B7

4.35e-06273214871856
Pubmed

Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate.

UGT2B4 UGT2B7

4.35e-06273210222050
Pubmed

Cloning and characterization of cDNAs encoding mouse Ugt1.6 and rabbit UGT1.6: differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

UGT1A3 UGT1A5

4.35e-0627328068691
Pubmed

Lysophosphatidic acid stimulates the proliferation and motility of malignant pleural mesothelioma cells through lysophosphatidic acid receptors, LPA1 and LPA2.

LPAR2 LPAR1

4.35e-06273218754873
Pubmed

Changes in S1P1 and S1P2 expression during embryonal development and primitive endoderm differentiation of F9 cells.

S1PR2 S1PR1

4.35e-06273216631609
Pubmed

Association of UGT2B7 and UGT1A4 Polymorphisms with Serum Concentration of Antiepileptic Drugs in Children.

UGT1A4 UGT2B7

4.35e-06273227795544
Pubmed

Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability.

UGT1A4 UGT1A3

4.35e-06273224641623
Pubmed

Identification and validation of the microRNA response elements in the 3'-untranslated region of the UDP glucuronosyltransferase (UGT) 2B7 and 2B15 genes by a functional genomics approach.

UGT2B7 UGT2B15

4.35e-06273228962835
Pubmed

Impact of UGT1A4 and UGT2B7 polymorphisms on lamotrigine plasma concentration in patients with bipolar disorder.

UGT1A4 UGT2B7

4.35e-06273239171428
Pubmed

S1P Stimulates Erythropoietin Production in Mouse Renal Interstitial Fibroblasts by S1P1 and S1P3 Receptor Activation and HIF-2α Stabilization.

S1PR2 S1PR1

4.35e-06273234502385
Pubmed

Pharmacokinetic and pharmacodynamic interaction of lorazepam and valproic acid in relation to UGT2B7 genetic polymorphism in healthy subjects.

UGT2B7 UGT2B15

4.35e-06273217687269
Pubmed

Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding.

LPAR2 LPAR1

4.35e-06273214625558
Pubmed

Cell surface targeting of mu-delta opioid receptor heterodimers by RTP4.

RTP4 OPRD1

4.35e-06273218836069
Pubmed

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33.

UGT2B4 UGT2B7

4.35e-06273217263731
Pubmed

Nomenclature of voltage-gated sodium channels.

SCN11A SCN7A

4.35e-06273211144347
Pubmed

Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling.

LPAR2 LPAR1

4.35e-06273215195086
Pubmed

Influence of valproic acid concentration and polymorphism of UGT1A4*3, UGT2B7 -161C > T and UGT2B7*2 on serum concentration of lamotrigine in Chinese epileptic children.

UGT1A4 UGT2B7

4.35e-06273226303110
Pubmed

Differential activation of receptors and signal pathways upon stimulation by different doses of sphingosine-1-phosphate in endothelial cells.

S1PR2 S1PR1

4.35e-06273225557733
Pubmed

Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

S1PR2 S1PR1

4.35e-06273218323526
Pubmed

Quantitative analysis of UGT2B28 mRNA expression by real-time RT-PCR and application to human tissue distribution study.

UGT2B28 UGT2B11

4.35e-06273221679149
Pubmed

Proximal tubule LPA1 and LPA2 receptors use divergent signaling pathways to additively increase profibrotic cytokine secretion.

LPAR2 LPAR1

4.35e-06273233427061
Pubmed

Cell type-specific localization of human cardiac S1P receptors.

S1PR2 S1PR1

4.35e-06273211967277
Pubmed

The significance of the altered expression of lysophosphatidic acid receptors, autotaxin and phospholipase A2 as the potential biomarkers in type 1 endometrial cancer biology.

LPAR2 LPAR1

4.35e-06273226327335
Pubmed

Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathways.

S1PR2 S1PR1

4.35e-06273223300082
Pubmed

Bearing variant alleles at uridine glucuronosyltransferase polymorphisms UGT2B7 -161C > T (rs7668258) or UGT1A4*3 c.142 T > G (rs2011425) has no relevant consequences for lamotrigine troughs in adults with epilepsy.

UGT1A4 UGT2B7

4.35e-06273237340142
Pubmed

LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells.

LPAR2 LPAR1

4.35e-06273217496233
Pubmed

Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population.

UGT2B4 UGT2B7

4.35e-06273215319348
Pubmed

Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate.

S1PR1 LPAR1

4.35e-06273235136060
Pubmed

Painful and painless mutations of SCN9A and SCN11A voltage-gated sodium channels.

SCN11A SCN9A

4.35e-06273232601768
Pubmed

Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization.

LPAR2 LPAR1

4.35e-0627329804623
Pubmed

S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress.

CCR7 S1PR1

4.35e-06273218164221
Pubmed

Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure.

LPAR2 LPAR1

4.35e-06273218703779
Pubmed

Important role of platelets in modulating endotoxin-induced lung inflammation in CFTR-deficient mice.

SELPLG CFTR

4.35e-06273224367540
Pubmed

N-glucuronidation of nicotine and cotinine by human liver microsomes and heterologously expressed UDP-glucuronosyltransferases.

UGT1A4 UGT1A3

4.35e-06273214570768
Pubmed

Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2).

LPAR2 LPAR1

4.35e-06273212215548
Pubmed

Modulation of LPA receptor expression in the human brain following neurotrauma.

LPAR2 LPAR1

4.35e-06273221234797
Pubmed

Lysophosphatidic acid signaling may initiate fetal hydrocephalus.

LPAR2 LPAR1

4.35e-06273221900594
Pubmed

UGT polymorphisms and lamotrigine clearance during pregnancy.

UGT1A4 UGT2B7

4.35e-06273229395496
Pubmed

Genome-wide association meta-analysis for total serum bilirubin levels.

UGT1A4 UGT1A3 UGT1A5

4.87e-061673319414484
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

UGT1A4 UGT1A3 UGT1A5

5.91e-061773320639394
Pubmed

A genome-wide assessment of variability in human serum metabolism.

UGT1A4 UGT1A3 UGT1A5

8.39e-061973323281178
Pubmed

Differential expression of S1P receptor subtypes in human bladder transitional cell carcinoma.

S1PR2 S1PR1

1.30e-05373230712233
Pubmed

A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis.

S1PR2 S1PR1

1.30e-05373223148237
Pubmed

Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia-induced remodeling.

LPAR2 LPAR1

1.30e-05373222015657
Pubmed

Role of sphingosine kinase and sphingosine-1-phosphate receptor in the liver pathology of mice infected with Plasmodium berghei ANKA.

S1PR2 S1PR1

1.30e-05373235333897
Pubmed

Differential expression of sphingosine-1-phosphate receptors in abdominal aortic aneurysms.

S1PR2 S1PR1

1.30e-05373222547907
Pubmed

SERCA and PMCA pumps contribute to the deregulation of Ca2+ homeostasis in human CF epithelial cells.

CFTR ATP2B2

1.30e-05373225661196
Pubmed

Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism.

UGT2B15 UGT2B28

1.30e-05373219572376
Pubmed

Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation.

SELPLG CCR7

1.30e-05373221659540
Pubmed

Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection.

CFTR IL1R1

1.30e-05373225500839
Pubmed

Enhanced Chemokine Receptor Recycling and Impaired S1P1 Expression Promote Leukemic Cell Infiltration of Lymph Nodes in Chronic Lymphocytic Leukemia.

CCR7 S1PR1

1.30e-05373226282174
Pubmed

The immune modulator FTY720 targets sphingosine-kinase-dependent migration of human monocytes in response to amyloid beta-protein and its precursor.

S1PR2 LPAR1

1.30e-05373215208267
Pubmed

Structural insights into PDZ-mediated interaction of NHERF2 and LPA(2), a cellular event implicated in CFTR channel regulation.

CFTR LPAR2

1.30e-05373224613836
Pubmed

Vascular smooth muscle migration and proliferation in response to lysophosphatidic acid (LPA) is mediated by LPA receptors coupling to Gq.

LPAR2 LPAR1

1.30e-05373216504475
Pubmed

[Regulation of Rho family G proteins and cell motility by the Edg family of sphingosin 1-phosphate receptors].

S1PR2 S1PR1

1.30e-05373211915348
InteractionCERS6 interactions

GPR21 P2RY12 ADGRG2 GPR35 LPAR2 ATP2B2 S1PR1 LPAR1

1.94e-09104678int:CERS6
InteractionSLC15A4 interactions

GPR21 GPR35 GLP1R TNFRSF10B ATP2B2

3.89e-0829675int:SLC15A4
InteractionKIAA2013 interactions

P2RY12 GPR35 LPAR2 RNF139 S1PR1 LPAR1 CLEC2B

1.14e-07116677int:KIAA2013
InteractionSACM1L interactions

P2RY12 GPR35 CFTR LPAR2 S1PR1 LPAR1 SLC35A5

7.20e-07152677int:SACM1L
InteractionTTYH3 interactions

P2RY12 GPR35 LPAR2 S1PR1 LPAR1

5.03e-0675675int:TTYH3
InteractionACP2 interactions

P2RY12 S1PR2 LPAR2 S1PR1 LPAR1

8.29e-0683675int:ACP2
InteractionSLC30A7 interactions

P2RY12 GPR35 LPAR2 LPAR1 CLEC2B

9.32e-0685675int:SLC30A7
InteractionPTDSS2 interactions

P2RY12 GPR35 LPAR2 S1PR1 LPAR1

1.17e-0589675int:PTDSS2
InteractionCMTM6 interactions

P2RY12 GPR35 LPAR2 S1PR1 LPAR1

1.17e-0589675int:CMTM6
InteractionITM2C interactions

GPX8 FURIN CFTR EIF2AK3 CLEC2B

1.96e-0599675int:ITM2C
InteractionTSPAN3 interactions

GPR21 TNFRSF10B S1PR1 LPAR1 CLEC2B

2.16e-05101675int:TSPAN3
InteractionATP2C1 interactions

SCN11A GPR35 SCN9A LPAR2 S1PR1

2.16e-05101675int:ATP2C1
InteractionXPO4 interactions

P2RY12 GLCE CFTR LRRC4 S1PR1

2.27e-05102675int:XPO4
InteractionTSPAN15 interactions

P2RY12 SPACA1 DPY19L4 S1PR2 LPAR2 S1PR1 LPAR1

3.61e-05276677int:TSPAN15
InteractionMFSD8 interactions

GPR21 P2RY12 S1PR2 LPAR1

4.42e-0559674int:MFSD8
InteractionGPR89A interactions

GPR21 P2RY12 ADGRG2 ATP2B2 LPAR1

4.95e-05120675int:GPR89A
InteractionTMBIM6 interactions

KCNA10 GPX8 GPR35 GLP1R UGT2B11

5.15e-05121675int:TMBIM6
InteractionUGT1A3 interactions

UGT1A3 UGT1A5

1.08e-045672int:UGT1A3
InteractionTM9SF3 interactions

P2RY12 FURIN CFTR S1PR1 LPAR1

1.14e-04143675int:TM9SF3
InteractionATP2A3 interactions

GPX8 GPR35 CFTR LPAR2 IL1R1 S1PR1

1.21e-04232676int:ATP2A3
InteractionNDUFAF1 interactions

GPR21 FURIN LPAR2 S1PR1 LPAR1

1.25e-04146675int:NDUFAF1
InteractionLMBR1 interactions

GPR21 P2RY12 S1PR1 LPAR1

1.32e-0478674int:LMBR1
InteractionTNPO3 interactions

P2RY12 GPR35 GLCE CFTR ATP2B2 S1PR1

1.36e-04237676int:TNPO3
InteractionUGT2B28 interactions

UGT2B28 UGT2B11

1.62e-046672int:UGT2B28
InteractionGINM1 interactions

GLCE CFTR TNFRSF10B ATP2B2

1.76e-0484674int:GINM1
InteractionSORCS1 interactions

FURIN CFTR

2.26e-047672int:SORCS1
InteractionUGT2B11 interactions

UGT2B28 UGT2B11

2.26e-047672int:UGT2B11
InteractionATP9A interactions

GPR35 LPAR2 ATP2B2 LPAR1

2.30e-0490674int:ATP9A
InteractionFAM241B interactions

GPR35 LPAR2 S1PR1 LPAR1

2.30e-0490674int:FAM241B
InteractionTMEM164 interactions

GPR21 P2RY12 LPAR1

2.52e-0437673int:TMEM164
InteractionGNAI1 interactions

FURIN S1PR2 S1PR1 ADCY5 OPRD1

2.62e-04171675int:GNAI1
InteractionXKR8 interactions

GPR21 CFTR

3.01e-048672int:XKR8
InteractionITPRIPL1 interactions

GPR21 LPAR2 S1PR1

3.18e-0440673int:ITPRIPL1
InteractionRPRM interactions

SPACA1 GPX8 DPY19L4 OPRD1

3.19e-0498674int:RPRM
InteractionDGAT1 interactions

GPR21 ATP2B2 CLEC2B

3.42e-0441673int:DGAT1
InteractionSMAGP interactions

SPACA1 GPX8 OPRD1

3.67e-0442673int:SMAGP
InteractionTNFRSF10C interactions

ATP11C LPAR2 TNFRSF10B LPAR1

3.85e-04103674int:TNFRSF10C
InteractionPAQR6 interactions

GPX8 GLP1R

3.86e-049672int:PAQR6
InteractionSAAL1 interactions

P2RY12 GLCE CFTR LPAR2 S1PR1

3.95e-04187675int:SAAL1
InteractionHTR3A interactions

GPX8 FURIN DPY19L4 ATP2B2

4.61e-04108674int:HTR3A
InteractionTTYH1 interactions

SLC4A7 DPY19L4 ATP11C S1PR2 ATP2B2 LPAR1

4.82e-04300676int:TTYH1
InteractionEXTL2 interactions

KCNA10 LPAR1 CLEC2B

5.13e-0447673int:EXTL2
InteractionALG10 interactions

P2RY12 ATP2B2 LPAR1

5.80e-0449673int:ALG10
Cytoband4q13

UGT2B4 UGT2B7 UGT2B15

1.73e-06157334q13
CytobandEnsembl 112 genes in cytogenetic band chr4q13

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.46e-06157735chr4q13
Cytoband2q37

UGT1A4 UGT1A3 UGT1A5

1.68e-05317332q37
CytobandEnsembl 112 genes in cytogenetic band chr2q37

UGT1A4 UGT1A3 GPR35 UGT1A5

4.77e-04226734chr2q37
Cytoband4q13.2

UGT2B28 UGT2B11

1.13e-03317324q13.2
CytobandEnsembl 112 genes in cytogenetic band chr12q15

PTPRR KCNMB4

3.63e-0356732chr12q15
GeneFamilyUDP glucuronosyltransferases

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

4.99e-1432568363
GeneFamilySphingosine 1-phosphate receptors|CD molecules

S1PR2 S1PR1

9.37e-055562206
GeneFamilyG protein-coupled receptors, Class A orphans

GPR21 GPR65 GPR35 GPR132

9.93e-0578564262
GeneFamilyLysophosphatidic acid receptors

LPAR2 LPAR1

1.40e-046562205
GeneFamilyADAM metallopeptidase domain containing|CD molecules

SELPLG CXCR6 SIGLEC9 CCR7 TNFRSF10B IL1R1 S1PR1

2.05e-04394567471
GeneFamilySodium voltage-gated channel alpha subunits

SCN11A SCN9A

3.35e-0495621203
CoexpressionVANLOO_SP3_TARGETS_DN

GPR155 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

4.03e-07103726MM919
CoexpressionSERVITJA_ISLET_HNF1A_TARGETS_DN

GLP1R UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.04e-06121726MM935
CoexpressionGSE15271_CXCR4_POS_VS_NEG_GC_BCELL_DN

TMEM176B ZNRF3 FURIN CCR7 RNF139 EIF2AK3

8.82e-06175726M7101
CoexpressionWENG_POR_TARGETS_LIVER_UP

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.38e-0553724MM1203
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_DN

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11 IL1R1

1.41e-05190726MM1311
CoexpressionHALLMARK_INFLAMMATORY_RESPONSE

CXCR6 CCR7 IL1R1 RTP4 GPR132 LPAR1

1.88e-05200726M5932
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 SHISA5 CCR7 RTP4 S1PR1

1.28e-0817073790f7640f04672c800cb28aea50004b1bb0565e8a
ToppCellfacs-GAT-Fat-18m-Lymphocytic-T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG SCN11A TMEM176B ZNRF3 CXCR6 FURIN GPR132

1.39e-0817273717a486c5d0430abb133eab9f087e2ef8b60f7d25
ToppCellfacs-MAT-Fat-3m-Lymphocytic-T_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 TMEM176B CXCR6 FURIN TNFRSF10B GPR132

1.63e-0817673771b3309ddadd035a1224fca4fc5946dc4c0283fe
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN4|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 RTP4 S1PR1

3.31e-0716773610c9fab3573c2948081aac2cec1798e46e59e38a
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 RTP4 S1PR1

3.55e-071697362de213b083f57f47be58427c0ce127fee9f85caa
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

GPR155 TMEM176B SCN7A SCN9A KCNMB4 LPAR1

3.55e-07169736a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN4|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 RTP4 S1PR1

3.81e-07171736f08402d0f42822c35673522043b652f8fb68d2f6
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN4|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 RTP4 S1PR1

3.94e-07172736d098e8a9c7666354803225cf2650faad436bab66
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELPLG GPR21 CXCR6 GLP1R S1PR1 GPR132

4.07e-07173736da0f1461643294f92e20b5e456a50211a2780a91
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

GPR155 TMEM176B SCN7A SCN9A KCNMB4 LPAR1

4.07e-071737366fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 RTP4 S1PR1

4.21e-07174736319bfafc66a21ad05ab35e0fd024c8b372a07165
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 P2RY12 PTPRR SLITRK4 SCN9A S1PR1

4.36e-07175736c36b4526970db9ccfbe2c70b00961fab9f13b133
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 P2RY12 PTPRR SLITRK4 SCN9A S1PR1

4.36e-07175736c1e082538f31b5c98ac63f71dcca4a1211a14708
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 P2RY12 PTPRR SLITRK4 SCN9A S1PR1

4.36e-071757362f9b5bdf8a62e8e99d1c4f677a8e5525bfd3b4ce
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 KCNMB4 CCR7 GPR132

4.66e-071777369d2d70d53b919fed3328812889a55e5e1a0759de
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-ILC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SELPLG CMTM1 GPR65 CXCR6 GPR132 CLEC2B

4.66e-071777369828504591599619649d41a78daf7c052729c669
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG SCN11A KCNMB4 CCR7 TNFRSF10B GPR132

5.14e-071807368cef63866c205df3825df84ce51fa61aa04ae491
ToppCellRA-16._Neuronal|World / Chamber and Cluster_Paper

GPR155 TMEM176B SCN7A SCN9A KCNMB4 LPAR1

5.31e-071817367d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCellfacs-GAT-Fat-24m-Lymphocytic|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 TMEM163 CCR7 GPR132

5.66e-07183736377c2c6fcb2fd41396dd7a7a90e9d7ccafccf2f0
ToppCellfacs-GAT-Fat-24m-Lymphocytic-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 TMEM163 CCR7 GPR132

5.66e-07183736f0a6f4f8563491c83fb991b9fb81e75fec7d1ace
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELPLG GPR21 TMEM176B CXCR6 KCNMB4 GPR132

6.43e-07187736fae08f34dc4b15352bd4d10bc6c924fe119b5d5e
ToppCelldroplet-Limb_Muscle-nan-24m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 TMEM163 CCR7 GPR132

6.43e-07187736890e80d0ee3cd548e4c1d0fa917c1d4080a06c13
ToppCelldroplet-Limb_Muscle-nan-24m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 TMEM163 CCR7 GPR132

6.43e-0718773667dc43f17f4b75c6a841bca5e2755fa895b390ab
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELPLG GPR21 TMEM176B CXCR6 KCNMB4 GPR132

6.43e-07187736e6b140b9fb582abf07aa6ea9bc437de3ba0d6de1
ToppCellCOPD-Myeloid-DC_Mature|COPD / Disease state, Lineage and Cell class

TMEM176B ATP11C CCR7 S1PR1 GPR132 LPAR1

6.63e-07188736de93ccb53edb8599da9e312db0e3af604c21f673
ToppCelldroplet-Mammary_Gland-nan-18m-Lymphocytic-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 SHISA5 CCR7 GPR132

6.63e-0718873613e72b0a2b62d95c805294645fca79d8f96e9e78
ToppCelldistal-Hematologic-IGSF21+_Dendritic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GPR155 SLC4A7 TMEM176B P2RY12 SCN9A GPR132

8.71e-07197736a357ee2ba9100dfaeba9ecae8138a2776bb54b0b
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCN11A PTPRR FURIN KCNMB4 S1PR1 OPRD1

9.24e-071997369735a1dc10910f02f1106b20ae5ab4c09c21305e
ToppCellwk_08-11-Mesenchymal-Fibroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GPX8 UNC5C SCN7A S1PR1 LPAR1 FAM162B

9.51e-07200736482dfbbd8958b64c31568dccbffe3cc9589f876b
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UNC5C SCN7A UGT2B15 IL1R1 LRRC4

2.22e-0612873558639cfdc70ff6764adcc5c1ce9eba9d033b8209
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

UNC5C SCN7A UGT2B15 IL1R1 LRRC4

2.22e-061287359b3c57d559a5ed8d590dd89b64a57a3227d8c684
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_P2ry12|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SCN11A GPR21 P2RY12 TMEM163 LPAR1

2.48e-0613173580630812f8894b9358d36dc2dd03fea7ee870502
ToppCellP03-Hematopoietic-Immune-immune_cell_unspecified|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GPR65 P2RY12 GPR35 CCR7 GPR132

4.67e-0614973543d756f81d532b5c7f2306e6af9d072d496cbc8e
ToppCellP03-Hematopoietic-Immune|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GPR65 P2RY12 GPR35 CCR7 GPR132

4.67e-061497351c5a2572741c47246d455c865e8e1677c9f49598
ToppCellLymphoid-Lymphoid-T_cells_(Cd4+_Tnaive-Tcm)|Lymphoid / shred on cell class and cell subclass (v4)

SELPLG SETX SHISA5 CCR7 S1PR1

5.31e-06153735ffb8ac88513e83d3ba01574e60beb5476154372b
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELPLG SHISA5 CCR7 SMIM33 GPR132

5.31e-061537350ad401cb70b9edfc6ae6ccba6879c6c2b6c4d296
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG TMEM217 P2RY12 UNC5C CCR7

5.66e-061557350e24e767a3895d31d34cabeaca0354aadae34e44
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG TMEM217 P2RY12 UNC5C CCR7

5.66e-06155735f3489a548a2c0cc2d9117ff85865c6089ea0835d
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 SMIM33 GPR132

5.84e-0615673539aa3adbee9f04cdc0055487d393edfa515e062b
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 SMIM33 GPR132

5.84e-06156735a09e3aefe78d63ad5428ad48c6f83e547eb819f6
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 SMIM33 GPR132

6.21e-06158735b1b1e50ddd231dcd10cc8e6bb68b2a5e0bb1450a
ToppCellHealthy/Control-Treg|Healthy/Control / Disease group and Cell class

GPR155 ADGRG2 CXCR6 GLCE SMIM33

6.40e-0615973516a322760c99f3e2c3b73cbb399f77868951d3cb
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 UGT1A5 GPR132

6.60e-0616073597c899df1b57fd2bd1867e02bfedf1920c00ad17
ToppCellImmune_cells-T_cells|World / Lineage and Cell class

SELPLG CXCR6 SHISA5 CCR7 S1PR1

7.22e-06163735c5afdb5e7700bbd3ee8276910f9c4b4b3bcc3266
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 GPR35 SCN7A GPR132

7.22e-061637358028636632c168dc50731d0ebecaf88a70daf81d
ToppCellfacs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELPLG GPR65 GPR35 CCR7 GPR132

7.44e-061647355ca7b69684a8bb12dd0b45e7ad94e30d16ed01ce
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

GPR155 TMEM176B SCN7A SCN9A KCNMB4

7.67e-061657356ed52cb756d21addf46c7f6c457458b01339fe04
ToppCelldroplet-Bladder-Unstain-18m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 CCR7 GPR132

7.89e-0616673500c53ee34ff4b988a9accd296bc0a2e14d9e7c49
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Th1|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SELPLG SLC9A8 GPR65 CXCR6 FURIN

8.13e-061677359c55ec8f70b86d4d3d5c2a6ecd9bff2dafe68c11
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

GPR155 SCN7A SCN9A KCNMB4 LPAR1

8.37e-0616873588c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCelldroplet-Bladder-nan-24m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 CCR7 GPR132

8.37e-06168735c6e0daa790dd5db20dd1ab8c1e7142484976d743
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 CCR7 GPR132

8.37e-06168735dc1143bd8db70c490167d73a525fd9b783eba960
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 CCR7 GPR132

8.37e-06168735a75d63ae8ad64b5560853775f6df398feb314ce8
ToppCellPND10-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELPLG GPR65 CCR7 GPR132 OPRD1

8.61e-06169735a83e4078db91ecedee637b28b12ec38640fe45f9
ToppCellPND10-Immune-Immune_Myeloid-DC-maDC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELPLG GPR65 CCR7 GPR132 OPRD1

8.61e-06169735f914aa8899fa170a09da31e5fad86de897ea789b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 UGT1A5 GPR132

8.86e-06170735c4f00c1acde1d3b521101e469101d10fd257653e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 GPR132

8.86e-061707357040f7b1e4d8d26db787449e557371c5d872c95a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 UGT1A5 GPR132

8.86e-06170735d3c1edaf0190d8927578043c372dba7477e75e14
ToppCellfacs-Thymus-Flowthrough-24m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 S1PR1

9.12e-06171735e2b72282244dee008e3b5d03667be9f26b7c2f6d
ToppCellfacs-Thymus-Flowthrough-24m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 S1PR1

9.12e-061717351064c20c37fae6cefb2eb4fa0628e4037a78179c
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CXCR6 SPACA1 CCR7 S1PR1 GPR132

9.38e-0617273509c03cc7717373f10e51281be76d53979fcb7ccd
ToppCellBronchial_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGRG2 CFTR SCN7A SCN9A ADCY5

9.64e-06173735e1de849dcd96063136bdac87e050ddbd55cabdcc
ToppCellfacs-MAT-Fat-18m-Lymphocytic-T_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 TMEM176B CXCR6 GPR132

9.64e-0617373597391a763c17ce0107c9e2386e88c417ac75a72e
ToppCellBronchial_Brush-Epithelial-Ionocytes|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGRG2 CFTR SCN7A SCN9A ADCY5

9.64e-06173735f2a8f4918c1fb68d98bc3f33cd624de0f0f11e06
ToppCellfacs-Marrow-T-cells|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR6 SHISA5 TMEM163 CCR7 S1PR1

9.64e-06173735806f94f5c3ac836ddffc389d3c2cd7e4da7a608d
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 GPR132

1.02e-05175735b66731573e79576fbf17538059cb8243dd4903c4
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 GPR132

1.02e-051757355f18077e5c3edc6a2708315db53683afa4a6d4a8
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 TBC1D7 GPR132

1.02e-051757352cd85b619f0d4771064db34959f154de3a40f15b
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 TBC1D7 GPR132

1.02e-051757355d9b1d398c1caead7538f19ce1ae207d3e127bfd
ToppCelldroplet-Pancreas-PANCREAS-30m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 KCNMB4 CCR7

1.02e-05175735ca2eabf03b70353e7eb15b6f622b2f9223a99e18
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 CCR7 GPR132

1.05e-0517673527c5ddd67de52101360ef7de8fcfa041066d97db
ToppCelldroplet-Fat-Scat-18m-Lymphocytic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR6 SHISA5 TMEM163 CCR7 GPR132

1.08e-05177735872f05dca01e6d89a0b69d1a34840f09a2fa1948
ToppCelldroplet-Fat-Scat-18m-Lymphocytic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR6 SHISA5 TMEM163 CCR7 GPR132

1.08e-0517773576be975de7ebb2f8f7ea642244757a6dd44acd72
ToppCellfacs-BAT-Fat-3m-Lymphocytic-T_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG ZNRF3 CXCR6 CCR7 GPR132

1.11e-051787357c101e3957ea9b0d4ebf619d1d02e7e64ae28915
ToppCellImmune_cells-T_cells|Immune_cells / Lineage and Cell class

SELPLG CXCR6 SHISA5 CCR7 S1PR1

1.11e-05178735af420242277e2a4e2524002a2914b0538f79a134
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 P2RY12 SHISA5 CCR7 RTP4

1.14e-05179735eadcb22045f66b37ca7ec041dd314cafa50b1911
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Lymphocytic-T_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 CCR7 GPR132

1.14e-051797358bf04a7ad1b0be6722ebfdceba3f083f07bf96c5
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 P2RY12 SHISA5 CCR7 RTP4

1.14e-05179735556f8e67475a6ece6acbe6f274b2451049000384
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG SHISA5 TMEM163 CCR7 S1PR1

1.17e-0518073586cdb1652f1736c38b501f07cf40ce99134cf597
ToppCellfacs-MAT-Fat-24m-Lymphocytic-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG SHISA5 CCR7 S1PR1 GPR132

1.17e-05180735f3f7a610db750fcb84d746a5ea0d8b57f9b7d901
ToppCellfacs-SCAT-Fat-24m-Lymphocytic|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG SHISA5 TMEM163 CCR7 S1PR1

1.17e-05180735115ce9f048f933704a19759948dcc933245e63c4
ToppCellfacs-MAT-Fat-24m-Lymphocytic|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG SHISA5 CCR7 S1PR1 GPR132

1.17e-05180735bb2f1b254371924b2045e9e1a81b6dbf4f00dd6a
ToppCelldroplet-Limb_Muscle-nan-21m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 CCR7 GPR132

1.20e-05181735923b369b1404103f124fcbffa866de26f9d68d33
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADRA1D UNC5C SCN7A ADCY5 FAM162B

1.20e-05181735451b87ac95154bb80018b8dd245b4a6389d81411
ToppCelldroplet-Limb_Muscle-nan-21m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 CCR7 GPR132

1.20e-051817357fd96238673c9596562c43e7c5ddbab7d0e6c0c6
ToppCelldroplet-Lung-nan-21m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 S1PR1

1.23e-051827350fbc70527059cab8be16ae7348c791dfff159604
ToppCelldroplet-Lung-nan-21m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 S1PR1

1.23e-051827354d27bd13d5507862e8cca5def655f93b5c919a0e
ToppCellfacs-Trachea-24m-Hematologic|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELPLG GPR65 CXCR6 FURIN GPR132

1.23e-05182735a6162498a8a41a7fdf84d744e4203f99dfb284fa
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELPLG SHISA5 CCR7 S1PR1 GPR132

1.27e-0518373527219ad7ecdeeb9e55e39772992e14f6c497d020
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

ADRA1D UNC5C LPAR1 ADCY5 FAM162B

1.27e-05183735fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCelldroplet-Fat-Mat-18m-Lymphocytic-T_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 GPR132

1.27e-05183735f7852779190e3ea835d0eedd415870d9fd789bc2
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-maDC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMEM176B ATP11C CCR7 S1PR1 GPR132

1.33e-051857357e3d9f5050e71e91021245c11101e994ae41d22b
ToppCelldroplet-Mammary_Gland-nan-3m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG SHISA5 CCR7 S1PR1 GPR132

1.33e-0518573502a2cbae9238c6c1e80b9a52a575e3b22f0eebb4
ToppCellfacs-Kidney-nan-18m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG SPACA1 SHISA5 CCR7 GPR132

1.33e-05185735a3b937163346d729115e6335336e33d3e71fccb0
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX GPR65 P2RY12 SHISA5 CCR7

1.33e-05185735a2cae8c657e4f4d121476798e424876f7e247973
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX GPR65 P2RY12 SHISA5 CCR7

1.33e-05185735d50406a9a5b8d75110ba5985741aa2293950c543
ToppCell5'-Adult-Distal_Rectal-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B IZUMO2 UNC5C UGT2B4 ADCY5

1.37e-051867354046b701aa29712d9f7c774f8955215122c3c003
ToppCellIPF-Myeloid-DC_Mature|World / Disease state, Lineage and Cell class

TMEM176B ATP11C CCR7 S1PR1 GPR132

1.37e-05186735d0d3953d9b199e0e792990b8551efb993393fe7e
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG CXCR6 SHISA5 CCR7 S1PR1

1.37e-051867351154a42d0fe18859dc289222a4ef39d1d742d4b4
ToppCelldroplet-Tongue-nan-24m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG GPR65 CXCR6 CCR7 GPR132

1.37e-051867353e16781b9646de971d953da2c49d4210a4c23fe3
ComputationalGenes in the cancer module 227.

UGT2B4 UGT2B7 UGT2B15

2.27e-0515413MODULE_227
ComputationalSteroid hormone and heme metabolism.

UGT2B4 UGT2B7 UGT2B15

2.79e-0516413MODULE_505
ComputationalNeighborhood of CD97

SELPLG GPR65 CLEC2B

3.96e-0438413GNF2_CD97
ComputationalGenes in the cancer module 146.

GPR65 CXCR6 S1PR2 LPAR1

5.91e-04102414MODULE_146
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

GPR65 CXCR6 FURIN

8.91e-0450413GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_NAIVE_3
DrugC1 11-32

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.86e-1618728CID000443077
DrugC11131

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.86e-1618728CID000443076
Drugestriol-16-glucuronide

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.32e-1521728CID000122281
Drugestradiol-3-glucuronide

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

3.16e-1523728CID000066651
Drug7-hydroxycoumarin glucuronide

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.72e-1429728CID000125641
DrugAC1Q6OQG

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

8.73e-1433728CID000009686
DrugBP-3,6-quinol

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

8.73e-1433728CID000119292
Drugmorphine hydrochloride

UGT1A4 UGT1A3 PRLHR UGT1A5 CFTR SCN9A UGT2B4 UGT2B7 UGT2B15 CCR7 UGT2B28 TNFRSF10B UGT2B11 EIF2AK3 RTP4 ADCY5 OPRD1

1.17e-134817217CID000004253
DrugAC1NOWCJ

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.47e-1335728CID005120112
Drug3-[(3S,5R,10S,13R,14S,17R)-3-[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.47e-1335728CID010436171
Drugestrone-3-glucuronide

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.47e-1335728CID000115255
Drugl-borneol

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.40e-1337728CID000010049
Drugharmol

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

4.75e-1340728CID000068094
Drugtestosterone glucuronide

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.89e-1341728CID000108192
Drugandrosterone glucuronide

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

8.89e-1343728CID000114833
Drug7,8-benzoquinoline

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

8.89e-1343728CID000009191
DrugMS-222

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.08e-1244728CID000011400
Drugsalicylamide

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.28e-1248728CID000005147
DrugAC1N8H7N

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11 OPRD1

2.89e-1278729CID004318740
DrugAC1NQGK1

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

4.51e-1252728CID005195977
Drugranirestat

UGT1A4 UGT1A3 UGT2B4 UGT2B7 UGT2B15

5.74e-127725ctd:C115070
Drugmenthol

UGT1A4 UGT1A3 ADGRG2 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.94e-1287729CID000001254
DrugR(-)-Denopamine

UGT1A4 UGT1A3 ADRA1D UGT1A5 UGT2B4 UGT2B7 UGT2B15

9.38e-1233727CID000003818
Drugphenolphthalein

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.13e-1158728CID000004764
Drugurochloralic acid

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.31e-1159728CID003036914
Drug4-hydroxybiphenyl

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.31e-1159728CID000007103
Drug4-hydroxyestrone

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.31e-1159728CID000018418
Drugacetaminophen glucuronide

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.31e-1159728CID000083944
DrugSN-38G

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.31e-1159728CID000443154
DrugUDP-alpha-d-xylopyranose

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.50e-1160728CID000001165
DrugDCNB

UGT1A4 UGT1A3 UGT1A5 SCN9A UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.78e-1195729CID000007443
DrugDNCB

UGT1A4 UGT1A3 GPX8 UGT1A5 SCN9A UGT2B4 UGT2B7 UGT2B15 CCR7 UGT2B28 UGT2B11

1.87e-111897211CID000000006
Drug3-OHBaP

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.26e-1163728CID000025890
DrugAC1L1OBF

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

3.02e-1120726CID000032736
DrugMeldola

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

4.26e-1168728CID000081507
Drug2,2,2-trichloroethanol

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.64e-1173728CID000008259
Drugeugenol

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.64e-1173728CID000003314
Drug7-hydroxycoumarin

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

9.55e-1175728CID005281426
DrugAS-3201

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

1.04e-1024726CID000153948
Druglithocholic acid

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 KCNMB4 UGT2B28 UGT2B11

1.10e-10116729CID000009903
Drug16-epiestriol

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.18e-1077728CID000003269
Drug4-nitrophenyl)imidazole

UGT1A4 UGT1A3 UGT1A5 UGT2B7 UGT2B15

1.25e-1011725CID000123155
Drugalpha-naphthoflavone

UGT1A4 UGT1A3 UGT1A5 CFTR UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.28e-10118729CID000011790
Drugbenzyloxyresorufin

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.32e-1078728CID000114982
Drugglucosiduronate

UGT1A4 UGT1A3 GLCE UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11 CLEC2B

1.57e-101717210CID000000610
Drugacridine

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.79e-1081728CID000009215
Drug5 alpha-androstane

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.41e-1084728CID000094144
Drug7-ethoxycoumarin

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.92e-1086728CID000035703
Drugpentoxyresorufin

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

3.21e-1087728CID000107683
Drugcotinine-N-glucuronide

UGT1A4 UGT1A3 UGT1A5 UGT2B7 UGT2B15

3.46e-1013725CID000000411
Drugtrans-3'-hydroxycotinine

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

3.63e-1029726CID000000414
Druguridine 5'-diphosphoglucuronic acid

UGT1A4 UGT1A3 GPX8 UGT1A5 CFTR UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

4.20e-101897210CID000000390
Drugtolcapone

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

4.52e-1030726CID004659569
DrugAC1L7AJI

UGT1A4 UGT1A3 PCDHGA11 PCDHGA10 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 TNFRSF10B UGT2B11

4.83e-102567211CID000003750
Drug4-aminobiphenyl

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.05e-1092728CID000007102
Drugp-nitroanisole

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.05e-1092728CID000007485
Drugpropranolol glucuronide

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7

5.38e-1014725CID000119515
Drug2-naphthol

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

5.51e-1093728CID000008663
Drugethoxyresorufin

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

6.54e-1095728CID000003294
DrugNNAL

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

6.86e-1032726CID000104856
Drugbutylated hydroxytoluene

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11 LPAR1

7.18e-10143729CID000031404
DrugDB04103

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.74e-1097728CID004469987
Drug1-naphthol

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

8.41e-1098728CID000007005
Drug3-hydroxyandrostan-17-one

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.16e-09102728CID000000225
Drug1'-hydroxyestragole

UGT1A4 UGT1A3 UGT1A5 UGT2B7 UGT2B15

1.17e-0916725CID000040003
Drugchrysin

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.58e-09106728CID005281607
Drug3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7

1.65e-0917725CID000003573
Drugfluconazole

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.70e-09107728CID000003365
Drugdisulfiram

UGT1A4 UGT1A3 UGT1A5 CFTR UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.74e-09158729CID000003117
DrugAC1MRGT8

UGT1A4 UGT1A3 UGT1A5 SCN9A UGT2B7 UGT2B15 OPRD1

1.75e-0967727CID003517815
DrugAC1LCF1F

UGT1A4 UGT1A3 UGT1A5 NPC1L1 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.05e-09161729CID000627275
Drug2-naphthylamine

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.12e-09110728CID000007057
Drugal-Badry

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11 LRRC4

2.55e-09165729CID000004545
DrugT4-G

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

3.08e-0919725CID000152424
Drugethoxyquin

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

3.24e-09116728CID000003293
Drugbuprenorphine hydrochloride solution

UGT1A4 UGT1A3 UGT1A5 UGT2B7 UGT2B15 OPRD1

3.33e-0941726CID000002476
DrugAC1Q7AUJ

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

3.47e-09117728CID000003303
Drug2-methoxyestradiol

UGT1A4 UGT1A3 UGT1A5 CFTR UGT2B4 UGT2B7 UGT2B15 UGT2B28 TNFRSF10B UGT2B11

3.62e-092367210CID000001573
Drugfibrates

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

3.72e-09118728CID000002797
DrugPTBP

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

3.88e-0942726CID000007393
DrugAC1NFJIQ

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

3.88e-0942726CID004659568
Drugbenzphetamine

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

3.97e-09119728CID000002341
DrugN-hydroxy-PhIP

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

4.49e-0943726CID000104954
Drug4-nitrophenol

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 KCNMB4 UGT2B28 UGT2B11

4.73e-09177729CID000000980
Drug8-azaguanine

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28

5.18e-0978727CID000008646
Drughexobarbital

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

6.66e-09127728CID000003608
DrugAC1L1FK5

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

7.53e-09129728CID000003272
Drugpropofol

UGT1A4 UGT1A3 UGT1A5 SCN7A SCN9A UGT2B4 UGT2B7 UGT2B15 IL1R1

9.19e-09191729CID000004943
Drugscopoletin

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15

1.15e-0850726CID005280460
Drugoltipraz

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.21e-08137728CID000047318
DrugHymecromone

UGT1A3 UGT2B4 UGT2B7 UGT2B15 UGT2B11

1.39e-0825725ctd:D006923
DrugN-acetylbenzidine

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7

1.39e-0825725CID000018787
DrugUDP-N-acetylglucosamine

UGT1A4 UGT1A3 UGT1A5 FURIN UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.56e-08203729CID000001167
Druganiline

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.60e-08142728CID000006115
Drug2 E1

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

1.89e-08145728CID006102788
Druglicochalcone A

UGT1A4 UGT1A3 UGT2B4 UGT2B7 UGT2B15

2.10e-0827725ctd:C070840
Drugdiflunisal

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7

2.10e-0827725CID000003059
DrugL-idaro-1,4-lactone

UGT2B4 UGT2B7 UGT2B15 UGT2B28 UGT2B11

2.55e-0828725CID000078997
Drug7-hydroxy-4-trifluoromethylcoumarin

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7

3.07e-0829725CID005375667
DrugAC1L9E0Q

UGT1A4 UGT1A3 UGT1A5 UGT2B7 UGT2B15

3.68e-0830725CID000443095
Diseaseplasma clozapine-to-N-desmethylclozapine ratio measurement

UGT2B4 UGT2B7 UGT2B15 UGT2B11

3.84e-099714EFO_0600040
DiseaseX-19141 measurement

UGT2B4 UGT2B7 UGT2B15 UGT2B11

2.16e-0813714EFO_0800799
DiseaseX-24947 measurement

UGT2B4 UGT2B7 UGT2B15 UGT2B11

2.18e-0722714EFO_0800910
DiseaseX-11793--oxidized bilirubin measurement

UGT1A4 UGT1A3 UGT1A5

7.41e-078713EFO_0021260
DiseaseSuccinimide measurement

UGT1A4 UGT1A3 UGT1A5

7.41e-078713EFO_0022118
DiseaseX-11530 measurement

UGT1A4 UGT1A3 UGT1A5

7.41e-078713EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A4 UGT1A3 UGT1A5

7.41e-078713EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A4 UGT1A3 UGT1A5

7.41e-078713EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A4 UGT1A3 UGT1A5

7.41e-078713EFO_0800696
DiseaseX-10458 measurement

UGT1A4 UGT1A3 UGT1A5

7.41e-078713EFO_0800692
DiseaseX-24849 measurement

UGT1A4 UGT1A3 UGT1A5

7.41e-078713EFO_0800909
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A4 UGT1A3 UGT1A5

7.41e-078713EFO_0802740
DiseaseX-16946 measurement

UGT1A4 UGT1A3 UGT1A5

7.41e-078713EFO_0800766
DiseaseX-11442 measurement

UGT1A4 UGT1A3 UGT1A5

1.11e-069713EFO_0021236
DiseaseX-11441 measurement

UGT1A4 UGT1A3 UGT1A5

1.11e-069713EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A4 UGT1A3 UGT1A5

1.11e-069713EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A4 UGT1A3 UGT1A5

1.11e-069713EFO_0801037
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A4 UGT1A3 UGT1A5

1.11e-069713EFO_0802127
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A4 UGT1A3 UGT1A5

1.11e-069713EFO_0801036
DiseaseX-11880 measurement

UGT1A4 UGT1A3 UGT1A5

1.11e-069713EFO_0800698
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A4 UGT1A3 UGT1A5

1.11e-069713EFO_0004570, GO_0009410
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A4 UGT1A3 UGT1A5

1.11e-069713EFO_0020691
DiseaseX-21448 measurement

UGT1A4 UGT1A3 UGT1A5

1.58e-0610713EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A4 UGT1A3 UGT1A5

1.58e-0610713EFO_0802185
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN7A SCN9A

1.58e-0610713DOID:0111294 (implicated_via_orthology)
DiseaseX-23974 measurement

UGT1A4 UGT1A3 UGT1A5

1.58e-0610713EFO_0800867
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN7A SCN9A

1.58e-0610713DOID:0080422 (implicated_via_orthology)
Diseasebilirubin measurement, response to tenofovir

UGT1A4 UGT1A3 UGT1A5

1.58e-0610713EFO_0004570, EFO_0009279
Diseasevitamin D deficiency

UGT1A5 UGT2B4 UGT2B7 UGT2B11

1.91e-0637714EFO_0003762
DiseaseX-21796 measurement

UGT1A4 UGT1A3 UGT1A5

2.17e-0611713EFO_0800825
Diseaseplasma N-desmethylclozapine measurement

UGT1A4 UGT1A5 UGT2B15

2.17e-0611713EFO_0600039
Diseaseinsomnia, bilirubin measurement

UGT1A4 UGT1A3 UGT1A5

2.17e-0611713EFO_0004570, EFO_0004698
Diseasehistidine betaine (hercynine) measurement

UGT1A4 UGT1A3 UGT1A5

2.17e-0611713EFO_0800972
Diseasealdosterone measurement

UGT1A4 UGT1A3 UGT1A5

2.17e-0611713EFO_0010219
Diseasebiliverdin measurement

UGT1A4 UGT1A3 UGT1A5

2.89e-0612713EFO_0021033
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN7A SCN9A

2.89e-0612713DOID:0060170 (implicated_via_orthology)
Diseasep-cresol glucuronide measurement

UGT1A4 UGT1A3 UGT1A5

2.89e-0612713EFO_0800079
Diseaseretinol dehydrogenase 16 measurement

UGT1A4 UGT1A3 UGT1A5

3.75e-0613713EFO_0802007
DiseaseCongenital bilateral aplasia of vas deferens

ADGRG2 CFTR

5.71e-062712C0403814
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A4 UGT1A3 UGT1A5

8.86e-0617713EFO_0004611, EFO_0007800
Diseasephosphatidylcholine 36:4 measurement

UGT2B4 UGT2B28 UGT2B11

1.06e-0518713EFO_0010382
Diseaseangiopoietin-related protein 1 measurement

UGT1A4 UGT1A3 UGT1A5

1.06e-0518713EFO_0801382
Diseaseurate measurement, spine bone mineral density

UGT1A4 UGT1A3 UGT1A5 KCNMB4

1.18e-0558714EFO_0004531, EFO_0007701
Diseasedisease progression measurement

UGT2B4 UGT2B7 UGT2B11 ADCY5

1.45e-0561714EFO_0008336
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN11A SCN9A

1.71e-053712C1833661
DiseasePrimary Erythermalgia

SCN11A SCN9A

1.71e-053712C0014805
Diseasetissue factor measurement

UGT1A4 UGT1A3 UGT1A5

1.72e-0521713EFO_0010623
Diseasexanthurenate measurement

UGT1A4 UGT1A3 UGT1A5

4.66e-0529713EFO_0010551
Diseaseresponse to dolutegravir

UGT1A4 UGT1A3 UGT1A5

5.17e-0530713EFO_0600017
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN11A SCN9A

1.19e-047712C0020075
DiseaseX-24418 measurement

UGT2B4 UGT2B15

1.19e-047712EFO_0800879
DiseaseCongenital Pain Insensitivity

SCN11A SCN9A

1.19e-047712C0002768
Diseasevanillylmandelate (VMA) measurement

UGT2B4 UGT2B15

1.19e-047712EFO_0800119
Diseasecerebrovascular disease (is_implicated_in)

P2RY12 GLCE

1.58e-048712DOID:6713 (is_implicated_in)
Diseasedeoxycholic acid glucuronide measurement

UGT2B7 UGT2B15

1.58e-048712EFO_0800575
Diseaseserum N-desmethylclozapine measurement

UGT1A5 UGT2B15

1.58e-048712EFO_0600043
DiseaseX-12844 measurement

UGT2B4 UGT2B15

2.03e-049712EFO_0021339
Diseasevitamin D measurement, COVID-19

UGT1A5 UGT2B4 UGT2B7

2.27e-0449713EFO_0004631, MONDO_0100096
Diseasepregnenetriol sulfate measurement

UGT1A4 UGT1A5

3.10e-0411712EFO_0800586
DiseaseDrugs used in diabetes use measurement

ZNRF3 PTPRR GLP1R UNC5C ADCY5

3.79e-04255715EFO_0009924
Diseasemetabolite measurement

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B15 UGT2B11

3.98e-04560717EFO_0004725
Diseasepregnenetriol disulfate measurement

UGT1A4 UGT1A5

4.38e-0413712EFO_0800587
DiseaseParkinson's disease (implicated_via_orthology)

PRLHR VPS13A ADCY5 OPRD1

5.68e-04157714DOID:14330 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN11A KCNA10 SCN7A SCN9A

6.54e-04163714DOID:1826 (implicated_via_orthology)
Diseaselymphocyte count

SLC4A7 ZNRF3 PCDHGA11 PCDHGA10 TBC1D7 S1PR2 CCR7 MEAK7 S1PR1 LPAR1 ADCY5

7.13e-0414647111EFO_0004587
Diseasealkaline phosphatase measurement

TMEM176B ZNRF3 SIGLEC9 UGT2B4 UGT2B7 UGT2B15 S1PR2 UGT2B11 ADCY5

7.16e-041015719EFO_0004533
DiseaseX-21441 measurement

UGT1A4 UGT1A5

7.58e-0417712EFO_0800814
Diseasecardiovascular disease

ADRA1D TBC1D7 UNC5C NPC1L1 S1PR2 CCR7

8.18e-04457716EFO_0000319
Diseasetestosterone measurement

UGT1A4 TMEM176B UGT1A5 UGT2B4 UGT2B7 UGT2B15 TNFRSF10B UGT2B11 ATP2B2 S1PR1

9.19e-0412757110EFO_0004908
Diseaseandrosterone glucuronide measurement

UGT2B4 UGT2B15

1.05e-0320712EFO_0800317
Diseasethyroxine measurement

UGT1A4 UGT1A3 UGT1A5

1.07e-0383713EFO_0005130
Diseasehormone measurement

UGT1A4 UGT1A3 UGT1A5

1.11e-0384713EFO_0004730
DiseaseHMG CoA reductase inhibitor use measurement

FURIN NPC1L1 UGT2B7 UGT2B15

1.13e-03189714EFO_0009932
Diseasecholelithiasis

UGT1A4 UGT1A3 UGT1A5

1.27e-0388713EFO_0004799
Diseasealcohol use disorder (implicated_via_orthology)

PRLHR ADRA1D GPR21 GLP1R

1.27e-03195714DOID:1574 (implicated_via_orthology)
Diseasevitamin D measurement

UGT1A4 UGT1A5 UGT2B4 UGT2B7 UGT2B11

1.31e-03336715EFO_0004631
Diseasehemoglobin A1 measurement

GPR155 PTPRR GLP1R VPS13A MEAK7 ADCY5

1.58e-03520716EFO_0007629
Diseasegallstones

UGT1A4 UGT1A3 UGT1A5

2.27e-03108713EFO_0004210

Protein segments in the cluster

PeptideGeneStartEntry
LLAVVLTVAFITFKC

UGT1A3

496

P35503
IILRKIFTTISFCIV

CFTR

331

P13569
TCITVDRFIVVVKAT

CXCR6

121

O00574
VATILFCIIATTFIV

EIF2AK3

526

Q9NZJ5
FKIFLVIICLHVVLV

ADGRG2

21

Q8IZP9
AIKVIIAVVVVFIVF

CCR7

261

P32248
KTLIIICALFTLVTV

GLCE

11

O94923
TLVVFVSVIYSCVKL

ADCY5

801

O95622
EVFIQVLIKLRVCFV

ASTE1

121

Q2TB18
VKFFIIGVTVLVVAV

ATP2B2

441

Q01814
VAVAAVSCIFLVFVI

PCDHGA11

696

Q9Y5H2
VSCIFLVFVIVLLAL

PCDHGA11

701

Q9Y5H2
LVKTVVIILGAFVVC

LPAR2

236

Q9HBW0
FLIFVRVICIVVSKL

GLP1R

321

P43220
ILIAKASVFFIVCVL

GPR155

106

Q7Z3F1
LLKTVVIVLGAFIIC

LPAR1

256

Q92633
VAAVSCVFLAFVIVL

PCDHGA10

701

Q9Y5H3
TKIIIGCFVAVTLLA

LRRC4

526

Q9HBW1
VAIFLSVVICKGFLI

MEAK7

206

Q6P9B6
VKVFIIIAVFFICFV

P2RY12

236

Q9H244
VVVFCSLKVVTALAQ

GPR35

186

Q9HC97
TVTKICVFLFAFVVP

OPRD1

211

P41143
VVIFLSIFVIIVTCL

PTPRR

231

Q15256
VLIIILCSVFAVVTI

NPC1L1

286

Q9UHC9
VSVLVVVISITIFCL

KCNA10

221

Q16322
SCAFIVLVFVTVFLV

FURIN

721

P09958
IIKVINFYLVCTLTI

DPY19L4

346

Q7Z388
FVVGVLIVVLTICAK

KCNMB4

181

Q86W47
AKVFAVLLSIVLCTV

GPX8

16

Q8TED1
TCQIFGFVVSVLKSV

GPR21

101

Q99679
KLTSVVFILICCFII

S1PR1

46

P21453
LLKTVTIVLGVFIVC

S1PR2

231

O95136
FVLTIGVIICVFIIF

SPACA1

221

Q9HBV2
ICVTLTVIIVCSVFI

IL1R1

341

P14778
TVIIVCSVFIYKIFK

IL1R1

346

P14778
SLAVFVFVVIVVSAC

IZUMO2

196

Q6UXV1
LTIIACFAVIVSAKR

FAM162B

116

Q5T6X4
NVVLDFCCFIVIIIT

OR14A16

201

Q8NHC5
KHSAIAVVVIFLVCF

GPR132

241

Q9UNW8
FCVELCLKVIVSLTV

RNF139

426

Q8WU17
FILLLVFIVVKCFTS

RTP4

231

Q96DX8
FKVTFTLVVSGIECI

TAS2R40

16

P59535
VVLILTVFVAFCLLV

SLITRK4

626

Q8IW52
ILALVATIFFVCTVV

SELPLG

326

Q14242
KVHIFTVIQLTCLVL

SLC4A7

1081

Q9Y6M7
TFCLLVVIVVVFAVC

PRLHR

276

P49683
NVVFIILFTGECVLK

SCN9A

1551

Q15858
TVIVAVFVLLAVCII

SMIM33

46

A0A1B0GW64
CDKVTEFFLLILVSV

SETX

451

Q7Z333
TALVFLSFCVIFVVV

SIGLEC9

356

Q9Y336
IFVLSVVTIIICFTC

SHISA5

116

Q8N114
KFEISFVIWCIVLVL

SLC9A8

376

Q9Y2E8
SCKILVFVAVEILLT

TBC1D7

231

Q9P0N9
IRALFLAVCVLKVIV

TMEM176B

206

Q3YBM2
AAKTLAIVVGVFVLC

ADRA1D

346

P25100
KKCFIIVGVLITTNI

CLEC2B

6

Q92478
FITITSLEICIVVFF

CMTM1

46

Q8IZ96
IVFTVLVFTVTLKLA

ATP11C

1001

Q8NB49
LIVGCIEVVFVTKFL

VPS13A

1151

Q96RL7
VCSELVKLVFCVLVS

SLC35A5

56

Q9BS91
VKLVFCVLVSFCVIK

SLC35A5

61

Q9BS91
FLLACVATVIFIITK

UGT2B4

496

P06133
VATVIFIITKCLFCV

UGT2B4

501

P06133
LLAVVLTVAFITFKC

UGT1A5

496

P35504
AAVVLIVAVFVCKSL

TNFRSF10B

221

O14763
FLLACVATVIFIITK

UGT2B11

496

O75310
VATVIFIITKFCLFC

UGT2B11

501

O75310
KLLVSITVTFVLCFT

GPR65

226

Q8IYL9
IFLAFFVVVSLVCLI

ZNRF3

221

Q9ULT6
FVVVSLVCLILLVKI

ZNRF3

226

Q9ULT6
VVVIVFCLSLIGKTR

SCN7A

1006

Q01118
LCVIVFILITVIGKL

SCN11A

786

Q9UI33
VVIFTLECLIKIFAL

SCN11A

1406

Q9UI33
CVATVIFIITKFCLF

UGT2B15

501

P54855
FLLACVATVIFVVTK

UGT2B28

496

Q9BY64
FLLVCVATVIFIVTK

UGT2B7

496

P16662
KIVLFLSFITILISC

TMEM217

66

Q8N7C4
IFLLSSICIVVKAIH

TMEM163

161

Q8TC26
AVIVCLAISVVVALF

UNC5C

386

O95185
LLAVVLTVAFITFKC

UGT1A4

496

P22310