Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	HMG_box	SOX4 SOX11 SOX12	7.60e-04	53	63	3	PF00505
Domain	HMG_BOX_2	SOX4 SOX11 SOX12	8.03e-04	54	63	3	PS50118
Domain	HMG	SOX4 SOX11 SOX12	8.03e-04	54	63	3	SM00398
Domain	-	SOX4 SOX11 SOX12	8.47e-04	55	63	3	1.10.30.10
Domain	HMG_box_dom	SOX4 SOX11 SOX12	1.38e-03	65	63	3	IPR009071
Domain	DAPIN	NLRP12 NLRP13	2.48e-03	22	63	2	PS50824
Domain	PYRIN	NLRP12 NLRP13	2.48e-03	22	63	2	PF02758
Domain	DAPIN	NLRP12 NLRP13	2.48e-03	22	63	2	IPR004020
Domain	PYRIN	NLRP12 NLRP13	2.48e-03	22	63	2	SM01289
Domain	NACHT	NLRP12 NLRP13	2.71e-03	23	63	2	PS50837
Domain	NACHT_NTPase	NLRP12 NLRP13	2.71e-03	23	63	2	IPR007111
Pubmed	The transcription factor Sry-related HMG box-4 (SOX4) is required for normal renal development in vivo.	SOX4 SOX11 SOX12 DES	7.84e-09	13	65	4	23559562
Pubmed	SOXC and MiR17-92 gene expression profiling defines two subgroups with different clinical outcome in mantle cell lymphoma.	SOX4 SOX11 SOX12	2.49e-08	4	65	3	26998831
Pubmed	SoxC transcription factors are essential for the development of the inner ear.	SOX4 SOX11 SOX12	6.21e-08	5	65	3	26504244
Pubmed	Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors.	SOX4 SOX11 SOX12	1.24e-07	6	65	3	18505825
Pubmed	The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties.	SOX4 SOX11 SOX12	1.24e-07	6	65	3	18403418
Pubmed	SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair.	SOX4 SOX11 SOX12	5.19e-07	9	65	3	31492871
Pubmed	SoxC Transcription Factors Promote Contralateral Retinal Ganglion Cell Differentiation and Axon Guidance in the Mouse Visual System.	SOX4 SOX11 SOX12	7.41e-07	10	65	3	28215559
Pubmed	Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators.	SOX4 SOX11 SOX12	1.35e-06	12	65	3	11071752
Pubmed	Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3.	SOX4 SOX11 SOX12	1.35e-06	12	65	3	7590241
Pubmed	SOXC proteins amplify canonical WNT signaling to secure nonchondrocytic fates in skeletogenesis.	SOX4 SOX11 SOX12	1.76e-06	13	65	3	25452386
Pubmed	Seven new members of the Sox gene family expressed during mouse development.	SOX4 SOX11 SOX12	1.76e-06	13	65	3	8441686
Pubmed	Cis-regulatory control of corticospinal system development and evolution.	SOX4 SOX11 SOX12	1.76e-06	13	65	3	22678282
Pubmed	Novel Regulatory Mechanisms for the SoxC Transcriptional Network Required for Visual Pathway Development.	SOX4 SOX11 SOX12	1.76e-06	13	65	3	28411269
Pubmed	Numerous members of the Sox family of HMG box-containing genes are expressed in developing mouse teeth.	SOX4 SOX11 SOX12	2.23e-06	14	65	3	8921394
Pubmed	Differential isoform expression and alternative splicing in sex determination in mice.	SOX4 SOX11 SOX12	2.79e-06	15	65	3	30871468
Pubmed	Ablation of the Sox11 Gene Results in Clefting of the Secondary Palate Resembling the Pierre Robin Sequence.	SOX4 SOX11 SOX12	2.79e-06	15	65	3	26826126
Pubmed	Sox11 prevents tumorigenesis of glioma-initiating cells by inducing neuronal differentiation.	SOX11 PLAG1	3.44e-06	2	65	2	19808959
Pubmed	Differential expression of SOX4 and SOX11 in medulloblastoma.	SOX4 SOX11	3.44e-06	2	65	2	12125983
Pubmed	SoxC transcription factors are required for neuronal differentiation in adult hippocampal neurogenesis.	SOX4 SOX11	3.44e-06	2	65	2	22378879
Pubmed	The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells.	SOX4 SOX11	3.44e-06	2	65	2	23318640
Pubmed	Spatio-temporal expression of Sox genes in murine palatogenesis.	SOX4 SOX11 SOX12	4.16e-06	17	65	3	27241892
Pubmed	SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling.	SOX4 SOX11 SOX12	4.98e-06	18	65	3	25761772
Pubmed	SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models.	SOX4 SOX11 SOX12	4.98e-06	18	65	3	25652387
Pubmed	Expression of Sox genes in tooth development.	SOX4 SOX11 SOX12	4.98e-06	18	65	3	26864488
Pubmed	Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors.	SOX4 SOX11 SOX12	5.91e-06	19	65	3	20596238
Pubmed	Expression of Sox transcription factors in the developing mouse pancreas.	SOX4 SOX11 SOX12	8.09e-06	21	65	3	12815626
Pubmed	The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas.	SOX4 SOX11 SOX12	8.09e-06	21	65	3	16306355
Pubmed	Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types.	SOX4 SOX11 SOX12	9.35e-06	22	65	3	24310815
Pubmed	SOX4, SOX11 and PAX6 mRNA expression was identified as a (prognostic) marker for the aggressiveness of neuroendocrine tumors of the lung by using next-generation expression analysis (NanoString).	SOX4 SOX11	1.03e-05	3	65	2	25804118
Pubmed	The closely related transcription factors Sox4 and Sox11 function as survival factors during spinal cord development.	SOX4 SOX11	1.03e-05	3	65	2	20646169
Pubmed	The transcription factor prospero homeobox protein 1 is a direct target of SoxC proteins during developmental vertebrate neurogenesis.	SOX4 SOX11	1.03e-05	3	65	2	29749639
Pubmed	Expression of Sox4 and Sox11 is regulated by multiple mechanisms during retinal development.	SOX4 SOX11	1.03e-05	3	65	2	23313252
Pubmed	Class-C SOX transcription factors control GnRH gene expression via the intronic transcriptional enhancer.	SOX4 SOX11	1.03e-05	3	65	2	21527504
Pubmed	Sox4 links tumor suppression to accelerated aging in mice by modulating stem cell activation.	SOX4 SOX11 SOX12	1.23e-05	24	65	3	25043184
Pubmed	A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings.	SOX4 SOX11 SOX12	1.39e-05	25	65	3	19369396
Pubmed	Catenary cultures of embryonic gastrointestinal tract support organ morphogenesis, motility, neural crest cell migration, and cell differentiation.	DES NOS1	2.06e-05	4	65	2	10090150
Pubmed	Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors.	SOX4 SOX11 SOX12	2.44e-05	30	65	3	35830813
Pubmed	Distinct expression of select and transcriptome-wide isolated 3'UTRs suggests critical roles in development and transition states.	SOX4 SOX11 SOX12	3.27e-05	33	65	3	33951080
Pubmed	Cooperative function of POU proteins and SOX proteins in glial cells.	SOX4 SOX11	3.43e-05	5	65	2	9632656
Pubmed	Roles of Sox4 in central nervous system development.	SOX4 SOX11	5.13e-05	6	65	2	10925158
Pubmed	Emerin interacts in vitro with the splicing-associated factor, YT521-B.	PSME1 YTHDC1	5.13e-05	6	65	2	12755701
Pubmed	Late embryonic and postnatal development of interstitial cells of cajal in mouse esophagus: distribution, proliferation and kit dependence.	DES ANO1	5.13e-05	6	65	2	22269660
Pubmed	Phosphorylation of the neurogenic transcription factor SOX11 on serine 133 modulates neuronal morphogenesis.	SOX4 SOX11	5.13e-05	6	65	2	30385877
Pubmed	Sox gene expression during neuronal development.	SOX4 SOX11	5.13e-05	6	65	2	7821514
Pubmed	Two novel transcripts encoding two Ankyrin repeat containing proteins have preponderant expression during the mouse spermatogenesis.	POTEB2 POTEB	5.13e-05	6	65	2	17171436
Pubmed	The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network.	SOX4 SOX11	5.13e-05	6	65	2	23933087
Pubmed	SOX4 regulates gonad morphogenesis and promotes male germ cell differentiation in mice.	SOX4 SOX11 SOX12	6.31e-05	41	65	3	28118982
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TPP2 KNTC1 GTF3C1 VPS8 SF3A3 PRPF6 DDX60L PSME1 DDX41 TOP2B LRCH3	6.75e-05	1440	65	11	30833792
Pubmed	Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.	SOX4 SOX11 PDE9A RASGEF1B NOS1 NOTCH2	7.40e-05	376	65	6	24154525
Pubmed	POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.	POTEB2 POTEB	9.56e-05	8	65	2	12475935
Pubmed	Prolonged Sox4 expression in oligodendrocytes interferes with normal myelination in the central nervous system.	SOX4 SOX11	9.56e-05	8	65	2	17515609
Pubmed	Striking parallels between carotid body glomus cell and adrenal chromaffin cell development.	SOX4 SOX11	9.56e-05	8	65	2	29807017
Pubmed	Sox4-deficiency syndrome in mice is an animal model for common trunk.	SOX4 DES	9.56e-05	8	65	2	9815146
Pubmed	Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators.	SOX4 SOX11	1.23e-04	9	65	2	12100890
Pubmed	Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice.	ANO1 ADCY3	1.23e-04	9	65	2	26067252
Pubmed	Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.	SOX4 SOX12 DES P3H2	1.41e-04	140	65	4	26930384
Pubmed	Many sequence variants affecting diversity of adult human height.	MYO1F RASGEF1B PLAG1 ADCY3	1.53e-04	143	65	4	18391951
Pubmed	From head to toes: the multiple facets of Sox proteins.	SOX4 SOX11	1.53e-04	10	65	2	10037800
Pubmed	Splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3.	TPP2 DES	1.53e-04	10	65	2	1682057
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	SOX4 PDE9A NCKAP1 BUB1 TTC21B SF3A3 PRPF6 DDX41 WNK1 LRCH3	1.61e-04	1321	65	10	27173435
Pubmed	Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system.	SOX4 SOX11	1.87e-04	11	65	2	20147379
Pubmed	SoxC transcription factors shape the epigenetic landscape to establish competence for sensory differentiation in the mammalian organ of Corti.	SOX4 SOX11	1.87e-04	11	65	2	37585469
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	DES GTF3C1 NCKAP1 SF3A3 YTHDC1 TRIB1 TOP2B NOTCH2	1.92e-04	857	65	8	25609649
Pubmed	De novo genic mutations among a Chinese autism spectrum disorder cohort.	NCKAP1 YTHDC1	2.24e-04	12	65	2	27824329
Pubmed	Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.	BUB1 DDX41	2.24e-04	12	65	2	16595651
Pubmed	Single cell transcriptomics reveals lineage trajectory of retinal ganglion cells in wild-type and Atoh7-null retinas.	SOX4 SOX11	2.24e-04	12	65	2	33674582
Pubmed	Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells.	SOX4 SOX11	2.24e-04	12	65	2	23649630
Pubmed	Widespread Differential Expression of Coding Region and 3' UTR Sequences in Neurons and Other Tissues.	SOX11 SOX12	2.24e-04	12	65	2	26687222
Pubmed	Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation.	DES NOTCH2	2.65e-04	13	65	2	11171333
Pubmed	Usp11 controls cortical neurogenesis and neuronal migration through Sox11 stabilization.	SOX4 SOX11	2.65e-04	13	65	2	33579706
Pubmed	Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex.	SOX4 SOX11	2.65e-04	13	65	2	35915179
Pubmed	Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families.	SOX4 SOX11	2.65e-04	13	65	2	12194848
Pubmed	Opposing Effects of Growth and Differentiation Factors in Cell-Fate Specification.	SOX4 SOX11	2.65e-04	13	65	2	31155355
Pubmed	The genetics of NOD-like receptors in Crohn's disease.	NLRP12 NLRP13	3.08e-04	14	65	2	20403135
Pubmed	NALPs: a novel protein family involved in inflammation.	NLRP12 NLRP13	3.08e-04	14	65	2	12563287
Pubmed	Bmp in podocytes is essential for normal glomerular capillary formation.	DES NOTCH2	3.08e-04	14	65	2	18272846
Pubmed	FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons.	SOX4 SOX11	3.08e-04	14	65	2	35613274
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	GTF3C1 NCKAP1 PRPF6 HERC1 SMC5 SYNGAP1	3.35e-04	497	65	6	36774506
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	TPP2 SOX11 RIPOR2 SF3A3 ADCY3	3.46e-04	322	65	5	26514267
Pubmed	Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.	DES NOTCH2	3.56e-04	15	65	2	17194759
Pubmed	Orchestration of Neuronal Differentiation and Progenitor Pool Expansion in the Developing Cortex by SoxC Genes.	SOX4 SOX11	3.56e-04	15	65	2	26203155
Pubmed	Differentially expressed genes in the testicular tissues of adenylyl cyclase 3 knockout mice.	ADCY3 DNTT	3.56e-04	15	65	2	27864010
Pubmed	Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method.	ARHGEF28 TTC21B	3.56e-04	15	65	2	12056414
Pubmed	The familial dysautonomia disease gene IKBKAP is required in the developing and adult mouse central nervous system.	NOS1 ADCY3	3.56e-04	15	65	2	28167615
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	NCKAP1 AUTS2 CPD ABCD1 SMC5 YTHDC1 TOP2B NOTCH2 SYNGAP1	3.86e-04	1203	65	9	29180619
Pubmed	Unraveling the genetic landscape of bladder development in mice.	SOX11 DES	4.06e-04	16	65	2	19303107
Pubmed	Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development.	DES NOTCH2	4.06e-04	16	65	2	24353058
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	MYO1F PRPF6 SMC5 TOP2B LRCH3	4.43e-04	340	65	5	29478914
Pubmed	Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus.	SOX4 PDE9A	4.59e-04	17	65	2	33084572
Pubmed	Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.	SF3A3 PRPF6 DDX41	4.62e-04	80	65	3	11991638
Pubmed	PLZF regulates fibroblast growth factor responsiveness and maintenance of neural progenitors.	SOX11 SOX12	5.76e-04	19	65	2	24115909
Pubmed	Primary cilia maintain corneal epithelial homeostasis by regulation of the Notch signaling pathway.	KRT12 NOTCH2	5.76e-04	19	65	2	27122169
Pubmed	Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex.	SOX4 SOX11	5.76e-04	19	65	2	34431536
Pubmed	Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation.	SOX4 SOX11	6.39e-04	20	65	2	12447396
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	GTF3C1 NOL12 SF3A3 PRPF6 DDX41	6.49e-04	370	65	5	22922362
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	NOL12 YTHDC1 DDX41 TOP2B	6.56e-04	210	65	4	16565220
Pubmed	Long-range enhancers regulating Myc expression are required for normal facial morphogenesis.	SOX11 ANO1	7.06e-04	21	65	2	24859337
Pubmed	Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development.	DES NOTCH2	8.48e-04	23	65	2	28036337
Pubmed	DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex.	SOX4 SOX11	8.48e-04	23	65	2	30329130
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	GTF3C1 NOL12 SF3A3 PRPF6 YTHDC1 DDX41 TOP2B SYNGAP1	8.98e-04	1082	65	8	38697112
Cytoband	2q14	BUB1 SANBR	1.08e-04	11	65	2	2q14
Cytoband	8q24.13	TBC1D31 TRIB1	1.21e-03	36	65	2	8q24.13
GeneFamily	SRY-boxes	SOX4 SOX11 SOX12	5.26e-06	19	33	3	757
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEB2 POTEB	2.49e-04	13	33	2	685
GeneFamily	Pyrin domain containing\|Pyrin and HIN domain family	NLRP12 NLRP13	9.44e-04	25	33	2	994
GeneFamily	NLR family	NLRP12 NLRP13	9.44e-04	25	33	2	666
GeneFamily	Ankyrin repeat domain containing	POTEB2 POTEB NOTCH2	9.61e-03	242	33	3	403
Coexpression	GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP	KNTC1 TBC1D31 RASGEF1B CPD SCLY TRIB1	4.69e-06	174	65	6	M333
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	SOX11 TBC1D31 GTF3C1 PDE9A TYW5 SANBR PRPF6 SMC5 SCLT1 WNK1	1.50e-05	629	63	10	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
ToppCell	Control-Myeloid-Monocytes\|Control / group, cell type (main and fine annotations)	NLRP12 RIPOR2 MYO1F SCLT1 NOTCH2	8.35e-06	189	65	5	3335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCell	NS-moderate-d_16-33-Myeloid-Neutrophil\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RIPOR2 MYO1F CPD DDX60L TRIB1	9.01e-06	192	65	5	545c3990cbe3c04bfd95a0ab7499d2c4af509be1
ToppCell	moderate-Myeloid-Neutrophil\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RIPOR2 MYO1F CPD DDX60L TRIB1	9.01e-06	192	65	5	8105408400dac5dcb0ce62b558433257559c9f09
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RIPOR2 MYO1F RASGEF1B SCLT1 NOTCH2	9.48e-06	194	65	5	dfe0ece81922bfd7c6673726d3ea2365cbdb5513
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RIPOR2 MYO1F CPD DDX60L TRIB1	9.96e-06	196	65	5	fe8d3f45a64323947c36b127355d5940eb56c0ca
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 DES YTHDC1 TRIB1 NOTCH2	9.96e-06	196	65	5	97ac47daf5bb07fa5dda3976e1ae402750f959b5
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RIPOR2 MYO1F CPD DDX60L TRIB1	9.96e-06	196	65	5	526d037bb12d81f1c235c60ddc787fbad0bbad77
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RIPOR2 MYO1F CPD DDX60L TRIB1	1.02e-05	197	65	5	340ce4fef244176fb52e38ffbcbdfda5ac3467dd
ToppCell	NS-critical-d_07-13-Myeloid-Neutrophil\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RIPOR2 MYO1F CPD DDX60L TRIB1	1.02e-05	197	65	5	f38037dfa6c33e9336130d0cc65eaba0f120efb9
ToppCell	moderate-Myeloid-Neutrophil\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RIPOR2 MYO1F CPD DDX60L TRIB1	1.05e-05	198	65	5	a6306dac34af5783f3a734ef1eaa7a0c03267b4f
ToppCell	critical-Myeloid-Neutrophil\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RIPOR2 MYO1F CPD DDX60L TRIB1	1.05e-05	198	65	5	4da73dc3acb29d70b160903600d2bf7fdab34333
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD8-positive,_alpha-beta_T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NCKAP1 C10orf67 NOL12 PLAG1	4.69e-05	136	65	4	9d7080f695de4ef183e3dbdc18ba464a3b8e3469
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ABRA DES P3H2 YTHDC1	6.34e-05	147	65	4	27e97a7b1dc296f52990b5810a52ab0a7ef2b9e6
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51AP2 KRT12 KSR2 DLEC1	6.86e-05	150	65	4	47ea08d7609e1d2382bf56ef9e5c767e3597cf93
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NAP1L2 CFAP58 WNK1 PLEKHD1	7.41e-05	153	65	4	79c4f4ccdc8249c8461075c73491bc3b2d13344a
ToppCell	NS-critical-d_0-4-Lymphoid-NKT\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TBC1D31 NAP1L2 AUTS2 PLEKHD1	7.60e-05	154	65	4	08ffa4b6f4a1c3de037acf9d30bd14c195738ad9
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cbln4_Fezf2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KRT12 RASGEF1B CFAP58 TRIB1	8.81e-05	160	65	4	d8241404d775f9a709abdf17988f36293fcf4c58
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 SOX11 MAGED4 AUTS2	9.02e-05	161	65	4	bd520c9a1927d5d5355b4421e6b90b58bfb76a42
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TPP2 SOX12 NAP1L2 DLEC1	9.02e-05	161	65	4	5fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX11 RGCC ADCY3 SYNGAP1	9.24e-05	162	65	4	c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX11 RGCC ADCY3 SYNGAP1	9.24e-05	162	65	4	f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX11 RGCC ADCY3 SYNGAP1	9.24e-05	162	65	4	5d902bb31e691aea9749617cc88303c2448f24b8
ToppCell	droplet-Fat-Gat-18m-Myeloid-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP12 RIPOR2 MYO1F TRIB1	9.46e-05	163	65	4	3d12a8ca97005308403a3ab136af483ab25f9b0e
ToppCell	droplet-Fat-Gat-18m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP12 RIPOR2 MYO1F TRIB1	9.92e-05	165	65	4	c3ca2b35299294a5e3d1881fd11617e3ab720692
ToppCell	facs-Heart-LV-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DES NLRP12 RIPOR2 DNTT	9.92e-05	165	65	4	84eca6a0f5e996b6955ae79fa102af239098fe8f
ToppCell	facs-Heart-LV-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DES NLRP12 RIPOR2 DNTT	9.92e-05	165	65	4	af59a095ecc6758abc13d763c00e44447c488167
ToppCell	droplet-Fat-Gat-18m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP12 RIPOR2 MYO1F TRIB1	9.92e-05	165	65	4	af32eae9324ef053f4f76e2144fb84c6e264c482
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX11 MAGED4 P3H2 ANO1	1.06e-04	168	65	4	e40a3f85be7e9bb23bfbc1f9cb5e5fc54bb43863
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX11 MAGED4 P3H2 ANO1	1.06e-04	168	65	4	b1d6c35a5ae69c8638afd68c2be5bc9ce6fd2659
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Interneuron\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	SOX4 SOX11 RIPOR2	1.13e-04	64	65	3	fefabdf8d72a8f3caf78eb79d759edb475bdb2ad
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 RGCC CFAP58 DNTT	1.22e-04	174	65	4	0fccd90ef72ec2e5eb369fe6d6d126c60886485a
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 RGCC CFAP58 DNTT	1.22e-04	174	65	4	b2fc2a756f8e373ad903bd416d9de703d945fa1c
ToppCell	P03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ARHGEF28 RGCC ANO1 WNK1	1.27e-04	176	65	4	f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGEF28 P3H2 RGCC ANO1	1.33e-04	178	65	4	a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGEF28 P3H2 RGCC ANO1	1.33e-04	178	65	4	b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAD51AP2 ARHGEF28 P3H2 AUTS2	1.36e-04	179	65	4	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 SOX11 PDE9A RASGEF1B	1.42e-04	181	65	4	4e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 SOX11 PDE9A RASGEF1B	1.42e-04	181	65	4	ad30c01290fb98adbd0caed301a584761212c977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 SOX11 PDE9A RASGEF1B	1.42e-04	181	65	4	3a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NAP1L2 PLAG1 SCLY TRIB1	1.42e-04	181	65	4	9275531e896e118cee043ed94fd31a0070d9581c
ToppCell	facs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DES P3H2 ANO1 PKDREJ	1.48e-04	183	65	4	8d45dff06a199b1369576657f7f9dc0249c5f841
ToppCell	CF-Myeloid-Neutrophil\|CF / Disease state, Lineage and Cell class	RIPOR2 CPD DDX60L TRIB1	1.48e-04	183	65	4	da43827952e6fdee2ce94648c316182f272b321c
ToppCell	facs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DES P3H2 ANO1 PKDREJ	1.48e-04	183	65	4	421265fa15d5a028cb567bb0904e670473ef102b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RIPOR2 ANO1 NOS1 NOTCH2	1.51e-04	184	65	4	e2de27cee3ea80f9b7a9a7884ceceeaa67b3214a
ToppCell	NS-moderate-d_07-13-Myeloid-Neutrophil\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RIPOR2 MYO1F DDX60L TRIB1	1.51e-04	184	65	4	4c7d05f1a4556b13cedbaaf88d67ac32d09b109b
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NLRP12 RIPOR2 MYO1F CPD	1.51e-04	184	65	4	7ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CCDC13 C10orf67 CFAP58 DLEC1	1.54e-04	185	65	4	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPP2 SOX11 NCKAP1 WNK1	1.54e-04	185	65	4	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CCDC13 C10orf67 CFAP58 DLEC1	1.57e-04	186	65	4	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABRA DES AUTS2 CLHC1	1.60e-04	187	65	4	218c9b4f28499389c43005d9626af2ac01066027
ToppCell	CV-Severe-3\|Severe / Virus stimulation, Condition and Cluster	SOX4 KNTC1 RGCC BUB1	1.60e-04	187	65	4	68cb43a73945f5e252530da25613f6b3f484b4d5
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 KNTC1 SOX11 BUB1	1.60e-04	187	65	4	a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 KNTC1 SOX11 BUB1	1.60e-04	187	65	4	38ee33295a21db4aae5ba085df033db9693e41c6
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 KNTC1 SOX11 BUB1	1.60e-04	187	65	4	dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABRA DES AUTS2 CLHC1	1.60e-04	187	65	4	c7ac4b328efc2ebb72f71154661914193ff402ca
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-ELP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SOX4 PDE9A PSME1 TOP2B	1.67e-04	189	65	4	af391c321753743709e2da01a5aa7782d8cc54e3
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SOX4 PSME1 TOP2B DNTT	1.71e-04	190	65	4	f623f0bdece6002b68ac2207e99408b24a2b1194
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SOX4 AUTS2 TOP2B DNTT	1.74e-04	191	65	4	40813c397f533c2f4a6359a77757f736b6d9e07d
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RIPOR2 MYO1F CPD TRIB1	1.74e-04	191	65	4	b9b091d6b352d5128bb864ff52d2e5fb3387b766
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RIPOR2 MYO1F CPD TRIB1	1.74e-04	191	65	4	47156e5f1d790707f42f6283104a44b33af613e5
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DES P3H2 ANO1 NOTCH2	1.74e-04	191	65	4	96ff4cfbdcaec4b8568f9482d732dddd399121d3
ToppCell	COVID-19-kidney-TAL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGEF28 PDE9A P3H2 NOS1	1.74e-04	191	65	4	fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO1F CPD DDX60L TRIB1	1.74e-04	191	65	4	4d7f6216958fb202426b7a102e74682105ce7fca
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO1F CPD DDX60L TRIB1	1.74e-04	191	65	4	e979f6768065b8b3e522d66999ca794d844eccb4
ToppCell	COVID-19-kidney-Mito-rich_Distal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGEF28 PDE9A P3H2 NOS1	1.74e-04	191	65	4	0965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 SOX11 DES TRIB1	1.74e-04	191	65	4	4fcbc214853e115608b3be7b35639247ae41c9dc
ToppCell	P03-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ARHGEF28 RGCC ANO1 WNK1	1.78e-04	192	65	4	be5e246b2350398b985767b2fbede17a8dd8cc44
ToppCell	(210)_NKT_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	ARHGEF28 GTF3C1 MYO1F YTHDC1	1.78e-04	192	65	4	08dc0c019c594da7b9944db8fd706aa7780e6ae9
ToppCell	MatrixFB-Fibroblast-D_(Pericyte)\|MatrixFB / shred on cell class and cell subclass (v4)	ABRA RGCC ANO1 PLEKHD1	1.78e-04	192	65	4	630444302511f511ec6976bc045a3b4b9d8d4547
ToppCell	facs-Diaphragm\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 DES TRIB1 NOTCH2	1.78e-04	192	65	4	486cbf9791ca619e307e8b18aa70ce22111f4f26
ToppCell	NS-critical-d_0-4-Myeloid-Neutrophil\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RIPOR2 CPD DDX60L TRIB1	1.78e-04	192	65	4	3db74359c30172a51177e00eac1f48f483e15578
ToppCell	10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-ELP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SOX4 PDE9A PSME1 TOP2B	1.78e-04	192	65	4	38ec82aa2ec4f2c0a843e83f7fe54f6b2483ca3d
ToppCell	(21)_NKT_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	ARHGEF28 GTF3C1 MYO1F YTHDC1	1.78e-04	192	65	4	b0a573ddde2978485a857b8261ee1ee5ef68ecef
ToppCell	COVID-19-kidney-Myeloid\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RIPOR2 MYO1F CPD DDX60L	1.78e-04	192	65	4	0b9d22a222f1201e375f8e55cace9ef939febae4
ToppCell	EC-Sinusoidal_ECs\|EC / Lineage and Cell class	SOX4 RGCC RASGEF1B TRIB1	1.81e-04	193	65	4	1291b1d3494dcb4b9309f8bff63fb662e7eca0c8
ToppCell	Control-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	RIPOR2 MYO1F SCLT1 NOTCH2	1.81e-04	193	65	4	3479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	KNTC1 TBC1D31 BUB1 SCLT1	1.81e-04	193	65	4	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DES KSR2 YTHDC1 TRIB1	1.81e-04	193	65	4	1aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCell	10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SOX4 PSME1 TOP2B DNTT	1.85e-04	194	65	4	f64da5f62e29253d60b9546edf734ba5c17daae1
ToppCell	nucseq-Immune-Immune_Myeloid-pMON-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RIPOR2 MYO1F SCLT1 NOTCH2	1.85e-04	194	65	4	e237384b02be460d44eeada3026a5691c66f6fc1
ToppCell	nucseq-Immune-Immune_Myeloid-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RIPOR2 MYO1F SCLT1 NOTCH2	1.85e-04	194	65	4	0bc83ae79873a5e473e6e1e3111924cd003986a1
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RIPOR2 MYO1F CPD TRIB1	1.85e-04	194	65	4	4eef50c38e6edb2ef2cdcd14eb50805f6cd65bc8
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DES P3H2 ANO1 NOTCH2	1.85e-04	194	65	4	3bff2e4eb16719ab7419b2f94c9c6e7302aa6629
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TPP2 BUB1 SANBR SMC5	1.85e-04	194	65	4	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DES P3H2 ANO1 NOTCH2	1.85e-04	194	65	4	fdaf61cbe7f77ff5358d150b38adb1fe3778e961
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ARHGEF28 NCKAP1 CPD NOS1	1.88e-04	195	65	4	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ARHGEF28 NCKAP1 CPD NOS1	1.88e-04	195	65	4	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	10x5'v1-week_14-16-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SOX4 PSME1 TOP2B DNTT	1.88e-04	195	65	4	dc84a910b6f6eb9994cd683aa4fd813a82198e5f
ToppCell	Control-Myeloid-ncMonocyte\|Control / Disease state, Lineage and Cell class	RIPOR2 MYO1F SCLT1 NOTCH2	1.88e-04	195	65	4	fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_NK-NK_CD16\|lymph-node_spleen / Manually curated celltypes from each tissue	GTF3C1 MYO1F AUTS2 SCLT1	1.88e-04	195	65	4	e756733cf48768bf40058d6cf9039e52f7563133
ToppCell	Control-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	RIPOR2 MYO1F SCLT1 NOTCH2	1.88e-04	195	65	4	b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCell	control-Myeloid-Neutrophils_1\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RIPOR2 MYO1F SCLT1 TRIB1	1.92e-04	196	65	4	9c8623232c47af5de9f360fd5c5113362e37c6c9
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO1F CPD DDX60L TRIB1	1.92e-04	196	65	4	6230b4a26770d30f1ab83345c087f03be1be0f9e
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	SOX4 SOX11 RASGEF1B AUTS2	1.92e-04	196	65	4	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 SOX11 DES TRIB1	1.92e-04	196	65	4	3dc6394c5de1f875a19ad0e8799827fad29f8f02
ToppCell	COVID-19_Severe-Neu_0\|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients	RIPOR2 CPD DDX60L TRIB1	1.92e-04	196	65	4	4831243fcd680cf4821fa0246e758c3e7c13a962
ToppCell	BL-critical-LOC-Myeloid-Neutrophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RIPOR2 CPD DDX60L TRIB1	1.92e-04	196	65	4	f64d7fed31e418c55fe946744d78c3cbecec9bbf
ToppCell	Adult-Immune-monocyte-D122\|Adult / Lineage, Cell type, age group and donor	NLRP12 RIPOR2 MYO1F SCLT1	1.92e-04	196	65	4	16b0acb6157534938ca83d4e909471e33a7d3c52
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	SOX4 SOX11 RASGEF1B AUTS2	1.92e-04	196	65	4	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NLRP12 RIPOR2 MYO1F SCLT1	1.92e-04	196	65	4	cacd69be72e6167814f7adea7c5fa114f3103bbb
Drug	S-methylisothiourea sulfate	DES SCLY NOS1 DNTT	4.34e-06	39	64	4	CID000013347
Disease	FEV/FEC ratio	DES ARHGEF28 PDE9A KSR2 MYO1F ANO1 DLEC1 HERC1 TRIB1 ADCY3 TOP2B	3.83e-05	1228	61	11	EFO_0004713
Disease	BRICHOS domain-containing protein 5 measurement	NLRP12 NOL12	6.27e-05	6	61	2	EFO_0801430
Disease	Obesity, Morbid	KSR2 ADCY3	8.77e-05	7	61	2	C0028756
Disease	Coffin-Siris syndrome	SOX4 SOX11	3.23e-04	13	61	2	C0265338
Disease	body surface area	KNTC1 SF3A3 AUTS2 PLAG1 DLEC1 WNK1 TRIB1	3.55e-04	643	61	7	EFO_0022196
Disease	sexual dimorphism measurement	MYO1F RASGEF1B PCIF1 SF3A3 PLAG1 CPD HERC1 TRIB1 ADCY3	4.25e-04	1106	61	9	EFO_0021796
Disease	visceral adipose tissue measurement	KNTC1 RIPOR2 AUTS2 ABCD1 WNK1 ADCY3	4.73e-04	481	61	6	EFO_0004765
Disease	chronic obstructive pulmonary disease	SOX11 DES ARHGEF28 SF3A3 DLEC1 SCLT1 TOP2B	5.32e-04	688	61	7	EFO_0000341
Disease	free cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	PCIF1 TRIB1	8.61e-04	21	61	2	EFO_0022277
Disease	Squamous cell carcinoma of esophagus	DLEC1 PSME1 NOTCH2	1.02e-03	95	61	3	C0279626
Disease	preterm premature rupture of the membranes, spontaneous preterm birth	KSR2 TTC21B	1.53e-03	28	61	2	EFO_0006917, MONDO_0012511

Protein segments in the cluster

Peptide	Gene	Start	Entry
IGRHDKAREYIDRMI	TTC21B	121	Q7Z4L5
EDRHYMKRKEANAFE	BUB1	271	O43683
RKFDLVLEELRMFHE	RAD51AP2	966	Q09MP3
REERHQEYLKMLAER	NOL12	61	Q9UGY1
REFHDIERKFAEMYQ	NAP1L2	131	Q9ULW6
FMEPRYHVRREDLDK	POTEB2	91	H3BUK9
EEARRKGELRYMHSR	ABCD1	271	P33897
LEIHRHFFYSMKERR	ARHGEF28	901	Q8N1W1
RDRMHHDIVRLLDEY	NOTCH2	2051	Q04721
IREFQKTEDMRRYLH	LRCH3	426	Q96II8
RADMLKDVIREYDEH	MAGED4	436	Q96JG8
AEDFRMKYENELALR	KRT12	211	Q99456
LEKFRIEYERLHAVM	CFAP58	36	Q5T655
AFKREVMAYRQTRHE	KSR2	706	Q6VAB6
KEYVERAIEYRLHEM	HERC1	4681	Q15751
QYMGHYLIRDERKDR	DDX60L	721	Q5H9U9
SRDRYEELKRIDDAM	PDE9A	546	O76083
ERERLHMLREDYEHT	AUTS2	1151	Q8WXX7
ILEKFIRVYMREHDL	KNTC1	736	P50748
PMDYHEDDKRFRREE	ANO1	116	Q5XXA6
FEMAIRHFEQALREY	P3H2	226	Q8IVL5
YVLSMSEERHERVRK	DDX41	151	Q9UJV9
HRARMIEYFIDVARE	RASGEF1B	281	Q0VAM2
AELIFYMEELRAHVR	NCKAP1	406	Q9Y2A7
ISRMRDDNRYHEDIF	NOS1	1386	P29475
KEDYMDRLEHLRRQC	PCIF1	331	Q9H4Z3
ALRGKEEDFRMYHEI	CCDC13	681	Q8IYE1
HLKDEMARHLREYQD	DES	376	P17661
MDEFARYARLERKIN	GET1	66	O00258
RLRQHHDEYEDEIRM	CPD	1336	O75976
EYDHKRFREHDLPMV	ADCY3	801	O60266
LYKQRLDEFEMLERH	DLEC1	141	Q9Y238
VHELDEAEYRDIRLM	PSME1	201	Q06323
EAERLRLKHMADYPD	SOX11	101	P35716
EAERLRLKHMADYPD	SOX4	111	Q06945
ALAKEMRADADAYRR	TBC1D31	841	Q96DN5
MRADADAYRRKVDLE	TBC1D31	846	Q96DN5
KEYFADMERHRILFR	TOP2B	646	Q02880
ERDLRRYATHERKMI	DNTT	456	P04053
ADAIYAALDKRMDER	PRPF6	101	O94906
FMEPRYHVRREDLDK	POTEB	91	A0A0A6YYL3
DHVYFFRMVIRKDSR	PKDREJ	426	Q9NTG1
ADRMVEILFHYADRA	VPS8	546	Q8N3P4
ARMLDDLHKYRDVIV	SANBR	481	Q6NSI8
ERYMRRLEFHISKVD	RIPOR2	126	Q9Y4F9
AERAKRAEEHIYREM	ABRA	296	Q8N0Z2
RRAKEAEIMLHYIER	CLHC1	286	Q8NHS4
MDSRDRLREELHYEK	C10orf67	306	Q8IYJ2
DRRFYTRKDVRRHMV	PLAG1	191	Q6DJT9
AHMRDVRDYLEERLE	SCLY	321	Q96I15
DMHSYVRSRKRLREE	TRIB1	166	Q96RU8
SEVDRFMEREHLIFR	SYNGAP1	471	Q96PV0
RMRADVSHLKRFFEE	PLEKHD1	391	A6NEE1
REAERLRLKHMADYP	SOX12	91	O15370
FHYEEHLERMKRRSS	RGCC	51	Q9H4X1
YVARLHQLDAEKERM	TPP2	1056	P29144
SDYRKLEEMHQRFLV	SCLT1	441	Q96NL6
ARYRDKRVHDYDMRV	YTHDC1	646	Q96MU7
KRVHDYDMRVDDFLR	YTHDC1	651	Q96MU7
EQQRRYHEEKERLMD	SF3A3	6	Q12874
TEEYRRRRHTMDKDS	WNK1	51	Q9H4A3
RFHVDRRSKYDILME	GTF3C1	246	Q12789
ERFYERKRHLDLIEM	SMC5	251	Q8IY18
EEYRDFYARRMVLHI	TYW5	291	A2RUC4
DYVRRKFRLMEDRNA	NLRP12	131	P59046
LEEADHRRKYRENMK	NLRP13	171	Q86W25
RHVAVRKYEEMREEA	MYO1F	706	O00160