Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphatidylserine 1-acylhydrolase activity

PLAAT2 PLAAT3 PLAAT4

5.39e-0712283GO:0052739
GeneOntologyMolecularFunctionphospholipase A1 activity

PLAAT2 PLAAT3 PLAAT4

2.36e-0619283GO:0008970
GeneOntologyMolecularFunctionphospholipase A2 activity

PLAAT2 PLAAT3 PLAAT4

1.86e-0537283GO:0004623
GeneOntologyMolecularFunctioncarboxylic ester hydrolase activity

PLAAT2 PLAAT3 AADACL4 PLAAT4

6.50e-05157284GO:0052689
GeneOntologyMolecularFunctionN-acyltransferase activity

PLAAT2 PLAAT3 PLAAT4

3.86e-04102283GO:0016410
GeneOntologyMolecularFunctionphospholipase activity

PLAAT2 PLAAT3 PLAAT4

5.35e-04114283GO:0004620
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

PLAAT2 PLAAT3 AADACL4 ARSF PLAAT4 CPSF3

7.51e-04807286GO:0016788
GeneOntologyMolecularFunctionlipase activity

PLAAT2 PLAAT3 PLAAT4

9.32e-04138283GO:0016298
GeneOntologyMolecularFunctionproteoglycan binding

LRP1 HPSE

2.32e-0351282GO:0043394
GeneOntologyMolecularFunctionacyltransferase activity

PLAAT2 PLAAT3 PLAAT4 UBE3B HHATL

4.06e-03775285GO:0016746
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

PLAAT2 PLAAT3 PLAAT4

4.40e-03238283GO:0016747
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

HPSE HYAL3

9.13e-03103282GO:0004553
GeneOntologyBiologicalProcessN-acylphosphatidylethanolamine metabolic process

PLAAT2 PLAAT3 PLAAT4

1.49e-079263GO:0070292
GeneOntologyBiologicalProcessphosphatidylethanolamine acyl-chain remodeling

PLAAT2 PLAAT3 PLAAT4

2.91e-0711263GO:0036152
GeneOntologyBiologicalProcessphosphatidylethanolamine metabolic process

PLAAT2 PLAAT3 PLAAT4

7.06e-0630263GO:0046337
GeneOntologyBiologicalProcessphosphatidylcholine metabolic process

PLAAT2 PLAAT3 PLAAT4

1.27e-0478263GO:0046470
DomainLRAT-like_dom

PLAAT2 PLAAT3 PLAAT4

1.50e-078273IPR007053
DomainLRAT

PLAAT2 PLAAT3 PLAAT4

1.50e-078273PF04970
DomainEGF_3

LRP1 SNED1 MALRD1 HYAL3

3.41e-04235274PS50026
DomainEGF

LRP1 SNED1 MALRD1 HYAL3

3.41e-04235274SM00181
DomainEGF-like_dom

LRP1 SNED1 MALRD1 HYAL3

4.25e-04249274IPR000742
DomainEGF_1

LRP1 SNED1 MALRD1 HYAL3

4.65e-04255274PS00022
DomainEGF-like_CS

LRP1 SNED1 MALRD1 HYAL3

5.08e-04261274IPR013032
DomainEGF_2

LRP1 SNED1 MALRD1 HYAL3

5.38e-04265274PS01186
DomainEGF

LRP1 SNED1 MALRD1

7.79e-04126273PF00008
DomainLDLR_class-A_CS

LRP1 MALRD1

1.52e-0340272IPR023415
DomainLdl_recept_a

LRP1 MALRD1

1.92e-0345272PF00057
Domain-

LRP1 MALRD1

2.00e-03462724.10.400.10
DomainLDLRA_1

LRP1 MALRD1

2.18e-0348272PS01209
DomainLDrepeatLR_classA_rpt

LRP1 MALRD1

2.27e-0349272IPR002172
DomainLDLa

LRP1 MALRD1

2.27e-0349272SM00192
DomainLDLRA_2

LRP1 MALRD1

2.27e-0349272PS50068
DomainGlycoside_hydrolase_SF

HPSE HYAL3

2.65e-0353272IPR017853
DomainEGF_Ca-bd_CS

LRP1 SNED1

8.61e-0397272IPR018097
DomainEGF_CA

LRP1 SNED1

8.96e-0399272PS01187
DomainASX_HYDROXYL

LRP1 SNED1

9.13e-03100272PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1 SNED1

1.02e-02106272IPR000152
DomainEGF_CA

LRP1 SNED1

1.34e-02122272SM00179
DomainEGF-like_Ca-bd_dom

LRP1 SNED1

1.38e-02124272IPR001881
PathwayREACTOME_ACYL_CHAIN_REMODELLING_OF_PE

PLAAT2 PLAAT3 PLAAT4

8.72e-0629203M702
PathwayKEGG_GLYCOSAMINOGLYCAN_DEGRADATION

HPSE HYAL3

3.95e-0421202M3624
Pubmed

Characterization of the human tumor suppressors TIG3 and HRASLS2 as phospholipid-metabolizing enzymes.

PLAAT2 PLAAT3 PLAAT4

4.67e-10328319615464
Pubmed

Generation of N-acylphosphatidylethanolamine by members of the phospholipase A/acyltransferase (PLA/AT) family.

PLAAT2 PLAAT3 PLAAT4

9.33e-09628322825852
Pubmed

Structural and functional characterization of tumor suppressors TIG3 and H-REV107.

PLAAT3 PLAAT4

6.25e-07228225871522
Pubmed

Expression, purification and biochemical characterization of the N-terminal regions of human TIG3 and HRASLS3 proteins.

PLAAT3 PLAAT4

6.25e-07228220100577
Pubmed

Effects of apolipoprotein E on the human immunodeficiency virus protein Tat in neuronal cultures and synaptosomes.

LRP1 HPSE

1.87e-06328215264223
Pubmed

Structural basis for the acyltransferase activity of lecithin:retinol acyltransferase-like proteins.

PLAAT2 PLAAT3

1.87e-06328222605381
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

SNED1 P4HB AFG3L2

3.32e-0416828330631154
Pubmed

Roquin promotes constitutive mRNA decay via a conserved class of stem-loop recognition motifs.

P4HB AFG3L2

6.06e-044528223663784
Cytoband11q12.3

PLAAT2 PLAAT3

2.49e-043828211q12.3
GeneFamilyHRAS like suppressor family

PLAAT2 PLAAT3 PLAAT4

9.83e-0951931227
CoexpressionAtlasJC_hmvEC_top-relative-expression-ranked_1000

SNED1 PLAAT3 GPR4 PLAAT4 HPSE ERAP2 IL4I1

8.07e-05990247JC_hmvEC_1000
CoexpressionAtlasMyeloid Cells, MF.Thio5.II-480int.PC, CD115+ MHCII- F480int SiglecF- CD11c+, Peritoneal Cavity, avg-3

LRP1 EMP1 HPSE

1.02e-0481243GSM605865_100
CoexpressionAtlasMyeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3

LRP1 EMP1 HPSE

1.14e-0484243GSM605862_100
ToppCellSevere_COVID-19|World / Disease group,lineage and cell class (2021.01.30)

EMP1 PLAAT4 HPSE IL4I1

6.86e-0619828409fd456077bb3a657ad3b10c6cfe799b7266456a
ToppCellBAL-Severe|BAL / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EMP1 PLAAT4 HPSE IL4I1

6.86e-06198284454aee3f4fe6d0beeccc55200b4495f4f9b44feb
ToppCellBAL-Severe|BAL / Location, Disease Group, Cell group, Cell class (2021.03.09)

EMP1 PLAAT4 HPSE IL4I1

6.86e-06198284687f69c16343227854c882b4a0f3930ce534a3d2
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|Fibroblasts / Location, Cell class and cell subclass

LRP1 PLAAT3 EMP1 P4HB

7.14e-06200284f62833c63f9c6a94b6cc2ba8e2f960e67f093f48
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

LRP1 EMP1 P4HB

7.16e-0512928313cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

EMP1 IL4I1 KLHL23

9.52e-05142283d60d2a5d0876a552bc161fc4e2dfe180f88f03a5
ToppCellBAL-Mild-Myeloid-MoAM-MoAM2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EMP1 HPSE IL4I1

1.19e-041532835fbb90b8477f9fdabf3be19efd3068fbf70abee6
ToppCellBAL-Mild-Myeloid-MoAM-MoAM2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EMP1 HPSE IL4I1

1.19e-041532832c46183481e6d5a7fa190a743062509465f88e56
ToppCellBAL-Mild-Myeloid-MoAM-MoAM2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

EMP1 HPSE IL4I1

1.19e-04153283decc4f3098a9374a6b65c015a9d36380986290bf
ToppCellBAL-Mild-Myeloid-MoAM-MoAM2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EMP1 HPSE IL4I1

1.19e-0415328336a28805c0545c2f410c74a6ca0a70d840e75715
ToppCell18-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

PLAAT2 PLAAT4 IL4I1

1.21e-04154283ecfaed6fbffd1305a2216d48ecb33d8a182a9dd9
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

WDR35 EMP1 IL4I1

1.26e-04156283fc8b8aef29d6d1c0f0c1d08280d8aaff8d30535e
ToppCellPND03-Immune-Immune_Myeloid-DC-maDC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLAAT3 GPR4 IL4I1

1.26e-04156283095281ea78aefa0ee638191a03f8d6f62a86a9ff
ToppCellPND03-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLAAT3 GPR4 IL4I1

1.26e-0415628329b04143f71a0ecc600ac670abd1d521bee55fe7
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-2|TCGA-Colorectal / Sample_Type by Project: Shred V9

PLAAT4 HPSE IL4I1

1.28e-0415728367641089eeb1a502e01fb6ea35c3d19e21a5789e
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

EMP1 IL4I1 P4HB

1.35e-041602836d941e584360975e1fdbb2fc67af8e31f18759d8
ToppCellMild_COVID-19-Myeloid-MoAM2|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

EMP1 HPSE IL4I1

1.41e-04162283e5fc80ab19d513af6a7e677a5e67bfebca2e963b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-RGCs_early_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

PLAAT2 PLAAT3 PLAAT4

1.48e-04165283e460e03992781073cd836a655f15dda3157cea55
ToppCellControl-Myeloid-MoAM1,_IL1R2|Control / Condition, Lineage and Cell class

EMP1 HPSE IL4I1

1.54e-04167283ab6029ba037b6a499da8758864c44e174cde5587
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLAAT2 P2RY8 PLAAT4

1.54e-04167283484de3ca4a905067c18d06995601479eef8fc15e
ToppCellControl-Myeloid-MoAM1,_IL1R2|Myeloid / Condition, Lineage and Cell class

EMP1 HPSE IL4I1

1.54e-041672836e5140527437193f441ca96893b9a00d346614f3
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Intermediate_macrophages|bone_marrow / Manually curated celltypes from each tissue

LRP1 EMP1 IL4I1

1.56e-041682838ade4d098aeecda2d80c1cad1cebe9a063eae948
ToppCellPCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

P2RY8 PLAAT4 IL4I1

1.59e-0416928345ac692a0c9064ce6b6a31c2cd21c85ccf594670
ToppCellPCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_natural_killer_[NK]_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

P2RY8 PLAAT4 IL4I1

1.59e-041692833514a74980c7bd4bb76dbd06693f492e8dce21e0
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 HPSE HPS3

1.62e-04170283a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 HPSE HPS3

1.62e-04170283ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

P2RY8 SNED1 EMP1

1.85e-04178283375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 SIGIRR HYAL3

1.89e-04179283dd94ebe69ade6f51b94058abe066216f0de9feda
ToppCellPCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC2_(21)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

P2RY8 PLAAT4 IL4I1

1.95e-041812831fa882ee66e6f835acf3f293fd24dc7f8b1eff99
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC2_(21)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

P2RY8 PLAAT3 PLAAT4

2.04e-0418428333db879e629821fb75684e60f8f0749cf9623bdd
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell|356C / Donor, Lineage, Cell class and subclass (all cells)

P2RY8 ARSF PLAAT4

2.04e-041842835b4f18b26d03e8e5798cac70d124534749fc4cc0
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RY8 PLAAT4 IL4I1

2.08e-04185283e1fd66f4295056807aa29c0e4ce6b1a79cc8dfcf
ToppCellMild-CD4+_T|Mild / Disease group and Cell class

P2RY8 EMP1 IL4I1

2.08e-04185283c28ecb63146de1b02418e5a4fad0ae7c2b66a41d
ToppCell(5)_Epithelial_cells-(5)_Glands_duct|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

PLAAT3 PLAAT4 IL4I1

2.11e-04186283219b1aeca17503244fabbb780bca58f22c7c0f27
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLAAT2 PLAAT3 PLAAT4

2.14e-04187283d17352f769c3c66601b65d060626eecff41b0482
ToppCellCOVID-19_Moderate-NK_activated|COVID-19_Moderate / disease group, cell group and cell class

PLAAT3 PLAAT4 SIGIRR

2.21e-041892838f9f1e71857bed6d59c4b087b6a6970f30fd86be
ToppCellPCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC2_(21)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

P2RY8 PLAAT4 IL4I1

2.21e-04189283620d5a71b8cb6288540e2d2d848b9d4d66c1226f
ToppCellPCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_natural_killer_[NK]_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

P2RY8 PLAAT4 IL4I1

2.25e-041902835c6801046ab88aad76697984342319872a8f9e38
ToppCellASK428-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

PLAAT4 SIGIRR UBE3B

2.25e-04190283d649f7e17c4227787465dfc02037f791ff85378b
ToppCellPCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_B-im_lymphoid_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

P2RY8 PLAAT4 IL4I1

2.25e-0419028358f2278694931d4b104234810165715b510ab835
ToppCell(1)_Control_(PBS)-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

LRP1 SNED1 EMP1

2.25e-04190283ec0ab31266583a0966ac7615d5c0fabb7b7e66e8
ToppCellControl-Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PLAAT2 PLAAT3 P4HB

2.28e-041912833df5bbdb29bbcbcb8476fdf126b6d4c1ac67d64b
ToppCellPCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_B|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

P2RY8 PLAAT4 IL4I1

2.28e-04191283beb15dcc6df156ab342fc21a60a874c868780ce4
ToppCellPCW_07-8.5-Immune_Lymphocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

P2RY8 PLAAT4 IL4I1

2.28e-041912838911b88f70e5deed027177be2e6745b80308616b
ToppCellPCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC3_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

P2RY8 PLAAT4 IL4I1

2.32e-0419228342fed1a4c88e62dffda026503e5da1eb21fe877f
ToppCellCOVID-19-Myeloid-MoAM1,_IL1R2|Myeloid / Condition, Lineage and Cell class

PLAAT4 HPSE IL4I1

2.32e-04192283be9d5685fa03563322f147a4b38ed31e4da59487
ToppCellPCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

P2RY8 PLAAT4 IL4I1

2.32e-041922836eadf0f37beae22838e930ad897a9b89e5e12cdb
ToppCell(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells|(0)_Normal/No_Treatment / Stress and Cell class

LRP1 SNED1 EMP1

2.32e-041922837a2ad0bdae647b88e799e62767605f2f3c5a426f
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRP1 EMP1 HPSE

2.32e-041922830219093e7921a0db78053aee13ec480b520f5662
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LRP1 EMP1 HPSE

2.32e-04192283f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCellT/NK_cells-CD8+_Effector_T_cell|World / Lineage and Cell class

P2RY8 PLAAT3 PLAAT4

2.35e-0419328379fa0f482cd98642b1d38835cda98622f21e5bd0
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARSF PLAAT4 HPSE

2.35e-041932837cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EMP1 ARSF HPSE

2.35e-0419328396c85b250d04b5f400512097d925061c6dc2906b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLAAT2 PLAAT3 PLAAT4

2.35e-04193283778fcf8448e81fe18972d97ea8a30ab036d16fe5
ToppCellnormal_Lymph_Node-T/NK_cells-CD8_low_T|normal_Lymph_Node / Location, Cell class and cell subclass

PLAAT3 PLAAT4 SIGIRR

2.35e-04193283e20ad6b62ad3aa386aa10b7a5d057d24a64ad386
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLAAT2 PLAAT3 PLAAT4

2.39e-0419428364535db0420e53e4d777d2333b5051e63e8a3373
ToppCellnormal_Lymph_Node-T/NK_cells-Naive_CD8+_T|normal_Lymph_Node / Location, Cell class and cell subclass

PLAAT2 PLAAT3 PLAAT4

2.39e-0419428381b8f60d3b81e494051721ce9b8b6aefd415442c
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

LRP1 SNED1 EMP1

2.39e-04194283234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLAAT2 PLAAT3 PLAAT4

2.39e-04194283b0a7f5ca0c6f4f5764a8b35b5de80d82b828c66c
ToppCellMonocytes-Phagocytic_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

EMP1 HPSE IL4I1

2.39e-0419428340dbfdf1d7e6b73d120d8f802f08e573fe9a739e
ToppCellnormal_Lymph_Node-T/NK_cells-Naive_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

PLAAT2 PLAAT3 PLAAT4

2.39e-0419428372749ab1dd36a0d58624328961e1db08ccba2686
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

P2RY8 SNED1 EMP1

2.42e-04195283a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLAAT2 PLAAT3 SIGIRR

2.42e-04195283eb96439b59914954f684c4bfd9e9a6dbd3201a20
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

LRP1 SNED1 EMP1

2.42e-041952836a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellCV-Moderate-6|Moderate / Virus stimulation, Condition and Cluster

PLAAT3 ERAP2 IL4I1

2.42e-041952832b8a72d7e755b9655c7a496000d10ff06e50862b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

EMP1 PLAAT4 HHATL

2.42e-041952831e28617ca55e5f318a228357737b968dfac8cca0
ToppCellBAL-Mild-Myeloid-MoAM-MoAM1-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EMP1 HPSE IL4I1

2.46e-04196283bcd274db4955ea76ca26267a272c7d1929db24f4
ToppCellILEUM-inflamed-(1)_T_cell-(1)_Cytotoxic_T_cells|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

P2RY8 PLAAT3 PLAAT4

2.46e-04196283a8217c8e27027c0444ce072fe194404345c34022
ToppCellBAL-Control-cDC_10|Control / Compartment, Disease Groups and Clusters

P2RY8 WDR64 IL4I1

2.46e-04196283c32b7b7e6a4781c19c30c6e32d5563f82355deb0
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

P2RY8 PLAAT4 SIGIRR

2.46e-04196283072e0e29be4639344ead4ea6ad521e3338f5f8af
ToppCellBAL-Mild-Myeloid-MoAM-MoAM1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EMP1 HPSE IL4I1

2.46e-0419628380b9139d91dda4de69830d2d443859e047ab5503
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SNED1 P4HB

2.46e-04196283b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellMild_COVID-19-Myeloid-MoAM1|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

EMP1 HPSE IL4I1

2.46e-04196283ea3fbe81b4ecb6ccc8031f6d99da93c9f9f8c1aa
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY8 PLAAT4 SIGIRR

2.46e-04196283f424c45be7f34cbef76e1696dea10c1e3a9af2e0
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY8 PLAAT4 SIGIRR

2.46e-041962839bb87d20c25df0dc8e48bcb32b57f81a3dc1c0cd
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

PLAAT3 ERAP2 IL4I1

2.46e-041962837bced0cc2112697593c478fa291b8ed3941fb811
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SNED1 P4HB

2.46e-04196283787c6cd92035e0b1108c2c086c42a229016e476b
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 EMP1 P4HB

2.46e-04196283fcb275746bf51269ed8ba4cf93edb054a45f1ccd
ToppCellBAL-Mild-Myeloid-MoAM-MoAM1|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

EMP1 HPSE IL4I1

2.46e-041962837c8aa5853d7096628e35af665097c0299c329753
ToppCellBAL-Mild-Myeloid-MoAM-MoAM1-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EMP1 HPSE IL4I1

2.46e-04196283f60b220ed117bcc33e0f7bbf5b53d3b1422ebaca
ToppCellCOVID-19|World / Condition, Lineage and Cell class

EMP1 PLAAT4 IL4I1

2.50e-04197283228f641d79282cc3dc51b95a1f4b0cccfc200735
ToppCellNS-critical-d_16-33-Epithelial-IRC-IFNG_responsive_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PLAAT2 EMP1 PLAAT4

2.50e-041972838eb007fe2a60b1bfc9d0fd5fc92d2f21388806f7
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

P2RY8 PLAAT4 SIGIRR

2.50e-04197283836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell10x5'-Lung-Lymphocytic_T_CD8-Tem/emra_CD8|Lung / Manually curated celltypes from each tissue

P2RY8 PLAAT4 SIGIRR

2.50e-04197283a573a59e2271f5d0ce5de0b851951ab72659e060
ToppCell10x5'-Lung-Lymphocytic_T_CD8|Lung / Manually curated celltypes from each tissue

P2RY8 PLAAT4 SIGIRR

2.50e-04197283b2f5b35e931c1342e541ecf05933350c41612415
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 SNED1 GPR4

2.50e-041972832cb1f557ce1400398975de94638126b4522567f3
ToppCell3'_v3-Lung-Myeloid_Mac-Intermediate_macrophages|Lung / Manually curated celltypes from each tissue

EMP1 HPSE IL4I1

2.50e-04197283bcb4dc17dae705bd84ea6a2842d6b107562baeb7
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RY8 PLAAT4 ERAP2

2.50e-041972830b4fdf0131dd67a86ee3209fa66db0ca2e01a10e
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PLAAT3 GPR4 EMP1

2.50e-041972834e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCell(1)_B_cell-(101)_plasma|(1)_B_cell / immune cells in Peripheral Blood (logTPM normalization)

PLAAT2 PLAAT3 P4HB

2.50e-04197283c86fcd779f30074bdf0b23d763fee5b7e4a6e4f5
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RY8 PLAAT4 ERAP2

2.50e-04197283b3876076684781fb8384117f2cf367d828985986
ToppCellmild_COVID-19-CD8+_Tem|World / disease group, cell group and cell class (v2)

PLAAT2 P2RY8 PLAAT4

2.50e-0419728397fead264e986d922669a6006cbcec530c697df7
ToppCellBAL-Mild-Myeloid-MoAM|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EMP1 HPSE IL4I1

2.50e-041972830f40dd3530eb8d02e79b32f942efe3b65b8f6ee6
ToppCellBAL-Mild-Myeloid-MoAM|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

EMP1 HPSE IL4I1

2.50e-04197283a6aa5991d566c28440f7e24a30933e69669064f2
ToppCell(1)_B_cell-(10)_B_cell-(101)_plasma|(10)_B_cell / immune cells in Peripheral Blood (logTPM normalization)

PLAAT2 PLAAT3 P4HB

2.50e-04197283c7af5510e2dd69b6a044244b22e62b82f474fdbd
ToppCellsevere-Myeloid-CD14_Monocytes_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

LRP1 EMP1 P4HB

2.54e-04198283cb8f099cf4ed320615b1c60ddab86b89d8db9a43
ToppCellMild-Myeloid-Macrophages-FCN1_high|Mild / Condition, Lineage, Cell class and cell subclass

EMP1 HPSE IL4I1

2.54e-0419828317aab4dc3b2cd6eb7dda77dd51bdc20490fcfe19
ToppCellsevere-Myeloid-CD14_Monocytes_3|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

LRP1 EMP1 P4HB

2.54e-04198283374d7a24e00cd3f435ca980123ab3c6a441c9ad5
ToppCellControl-CD4+_T|Control / Disease group and Cell class

P2RY8 IL4I1 P4HB

2.54e-041982832682eea9b34cfc7e82891c1f1117d3c874107af6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

P2RY8 SNED1 EMP1

2.54e-041982830a172c6d997c7cfbad34b56e80121bd104dee67d
DiseaseMajor Depressive Disorder

LRP1 EMP1 HPSE

1.25e-03243263C1269683
Diseasephysical activity measurement

TLE7 EMP1 ERAP2

1.28e-03245263EFO_0008002
DiseaseUnipolar Depression

LRP1 EMP1 HPSE

1.50e-03259263C0041696
Diseaseankylosing spondylitis

MALRD1 ERAP2

2.91e-0391262EFO_0003898
Diseaseurate measurement

LRP1 PLAAT2 MALRD1 PLAAT4

7.38e-03895264EFO_0004531

Protein segments in the cluster

PeptideGeneStartEntry
YAHWAIYVGDGYVVH

PLAAT2

21

Q9NWW9
FHYCGSYLHAVRWIP

ARSF

446

P54793
VAGIKFWCYHAGHVL

CPSF3

146

Q9UKF6
VAYHEAGHAVAGWYL

AFG3L2

571

Q9Y4W6
RVTWYHLYDGFHGSI

AADACL4

366

Q5VUY2
YHHCFWLTVGVYVLG

OR8G2P

151

Q6IF36
YYHCNRHHWVFGVLL

P2RY8

81

Q86VZ1
TQYHHGYSYILGWIC

EMP1

126

P54849
WLCKYVYNHIGGEHS

HHATL

346

Q9HCP6
FGLCHHGNYLFWTEY

LRP1

746

Q07954
HKYLLVEFYAPWCGH

P4HB

41

P07237
YICTLPLWVDYFLHH

GPR4

66

P46093
GGEVIDSVTWHHYYL

HPSE

286

Q9Y251
YYVWVGAKHGFTLNH

MALRD1

316

Q5VYJ5
YIIGGYYWHPLSEVH

KLHL23

276

Q8NBE8
CWHLHDYLVDTLGPY

HYAL3

331

O43820
YIVHYEGHGWDQLIT

ERAP2

631

Q6P179
IYFAGEHTAYPHGWV

IL4I1

476

Q96RQ9
YRHWAIYVGDGYVVH

PLAAT3

21

P53816
CSHYGLIYPWVHVVI

HPS3

831

Q969F9
YEHWALYIGDGYVIH

PLAAT4

21

Q9UL19
LGIGGHYSLHEYSWV

SIGIRR

56

Q6IA17
WEGGVCHHVYKRVYR

SNED1

1366

Q8TER0
AVLVHAGWSCHDGYY

USP17L4

321

A6NCW7
HHVYTCGSGYIRVWD

TLE7

171

A0A1W2PR48
VYYGGFHGSHRVIIW

UBE3B

941

Q7Z3V4
SIAGIHWYHGTEGYV

WDR35

206

Q9P2L0
VRLWHALNGHYCGYF

WDR64

891

B1ANS9