Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium/calmodulin-dependent protein kinase activity	CAMK1D CAMK1G MAPKAPK5 MYLK2 PHKG1	2.33e-07	27	102	5	GO:0004683
GeneOntologyMolecularFunction	protein serine kinase activity	CAMK1D PAK5 MAP3K20 RIOK3 CAMK1G MAPKAPK5 PHKG1 STK33 MAP3K11 MAPK6 EIF2AK2 PRKX	3.38e-07	363	102	12	GO:0106310
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CAMK1D PAK5 MAP3K20 RIOK3 CAMK1G MAPKAPK5 MYLK2 PHKG1 STK33 MAP3K11 MAPK6 EIF2AK2 PRKX	4.45e-07	446	102	13	GO:0004674
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CAMK1D PAK5 MAP3K20 DGKA RIOK3 CAMK1G MAPKAPK5 MYLK2 PHKG1 PI4KB STK33 DGKK MAP3K11 MAPK6 EIF2AK2 PRKX	5.95e-07	709	102	16	GO:0016773
GeneOntologyMolecularFunction	kinase activity	CAMK1D PAK5 MAP3K20 DGKA RIOK3 CAMK1G MAPKAPK5 MYLK2 PHKG1 PI4KB STK33 DGKK MAP3K11 MAPK6 EIF2AK2 PRKX	1.58e-06	764	102	16	GO:0016301
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	CAMK1D PAK5 MAP3K20 DGKA RIOK3 CAMK1G MAPKAPK5 MYLK2 POLR3F PHKG1 PI4KB STK33 DGKK MAP3K11 MAPK6 EIF2AK2 PRKX	5.08e-06	938	102	17	GO:0016772
GeneOntologyMolecularFunction	protein kinase activity	CAMK1D PAK5 MAP3K20 RIOK3 CAMK1G MAPKAPK5 MYLK2 PHKG1 STK33 MAP3K11 MAPK6 EIF2AK2 PRKX	1.15e-05	600	102	13	GO:0004672
GeneOntologyMolecularFunction	nitric-oxide synthase regulator activity	ATP2B4 HSP90AA1 HSP90AB1	1.51e-05	10	102	3	GO:0030235
GeneOntologyMolecularFunction	CTP binding	HSP90AA1 HSP90AB1	2.58e-05	2	102	2	GO:0002135
GeneOntologyMolecularFunction	sulfonylurea receptor binding	HSP90AA1 HSP90AB1	7.73e-05	3	102	2	GO:0017098
GeneOntologyMolecularFunction	UTP binding	HSP90AA1 HSP90AB1	1.54e-04	4	102	2	GO:0002134
GeneOntologyMolecularFunction	phosphatidylinositol-5-phosphate binding	PLEKHF1 RS1 PLEKHA5	2.13e-04	23	102	3	GO:0010314
GeneOntologyMolecularFunction	pyrimidine ribonucleotide binding	HSP90AA1 HSP90AB1	2.56e-04	5	102	2	GO:0032557
GeneOntologyMolecularFunction	dATP binding	HSP90AA1 HSP90AB1	2.56e-04	5	102	2	GO:0032564
GeneOntologyMolecularFunction	adenyl deoxyribonucleotide binding	HSP90AA1 HSP90AB1	3.82e-04	6	102	2	GO:0032558
GeneOntologyMolecularFunction	purine deoxyribonucleotide binding	HSP90AA1 HSP90AB1	5.34e-04	7	102	2	GO:0032554
GeneOntologyMolecularFunction	TPR domain binding	HSP90AA1 HSP90AB1	7.09e-04	8	102	2	GO:0030911
GeneOntologyMolecularFunction	glutamate-gated calcium ion channel activity	GRIA1 GRIN2A	7.09e-04	8	102	2	GO:0022849
GeneOntologyMolecularFunction	phosphatidylinositol-4-phosphate binding	PLEKHF1 RS1 PLEKHA5	8.17e-04	36	102	3	GO:0070273
GeneOntologyMolecularFunction	deoxyribonucleotide binding	HSP90AA1 HSP90AB1	9.09e-04	9	102	2	GO:0032552
GeneOntologyMolecularFunction	disordered domain specific binding	HSP90AA1 HSP90AA2P HSP90AB1	1.03e-03	39	102	3	GO:0097718
GeneOntologyMolecularFunction	ATP-dependent protein folding chaperone	HSP90AA1 HSP90AA2P HSP90AB1	1.11e-03	40	102	3	GO:0140662
GeneOntologyMolecularFunction	calmodulin binding	CAMK1D CAMK1G MAPKAPK5 MYLK2 PHKG1 ATP2B4	1.17e-03	230	102	6	GO:0005516
GeneOntologyMolecularFunction	lipid kinase activity	DGKA PI4KB DGKK	1.20e-03	41	102	3	GO:0001727
GeneOntologyMolecularFunction	kinase binding	BLNK GRIA1 GRIN2A MAPKAPK5 EIF4ENIF1 FAM83F MAP3K11 MAPK6 CDH5 ATP2B4 MOB4 HSP90AA1 HSP90AB1	1.30e-03	969	102	13	GO:0019900
GeneOntologyMolecularFunction	scaffold protein binding	GRIA1 GRIN2A ATP2B4 HSP90AA1	1.32e-03	93	102	4	GO:0097110
GeneOntologyMolecularFunction	ATP-dependent diacylglycerol kinase activity	DGKA DGKK	1.38e-03	11	102	2	GO:0004143
GeneOntologyMolecularFunction	pyrimidine nucleotide binding	HSP90AA1 HSP90AB1	1.38e-03	11	102	2	GO:0019103
GeneOntologyMolecularFunction	JUN kinase kinase kinase activity	MAP3K20 MAP3K11	1.65e-03	12	102	2	GO:0004706
GeneOntologyMolecularFunction	phosphatidylinositol-3-phosphate binding	PLEKHF1 RS1 PLEKHA5	1.89e-03	48	102	3	GO:0032266
GeneOntologyMolecularFunction	glutamate-gated receptor activity	GRIA1 GRIN2A	3.34e-03	17	102	2	GO:0004970
GeneOntologyMolecularFunction	cell adhesion molecule binding	ATXN2L GRIN2A OLA1 TENM3 PTPRM FGB IGSF9 CDH5 HSP90AB1	3.57e-03	599	102	9	GO:0050839
GeneOntologyMolecularFunction	unfolded protein binding	ERO1B HSP90AA1 HSP90AA2P HSP90AB1	3.99e-03	126	102	4	GO:0051082
GeneOntologyMolecularFunction	intracellularly calcium-gated channel activity	TTYH1 BEST3	4.62e-03	20	102	2	GO:0141147
GeneOntologyMolecularFunction	intracellularly calcium-gated chloride channel activity	TTYH1 BEST3	4.62e-03	20	102	2	GO:0005229
GeneOntologyMolecularFunction	protein kinase binding	BLNK GRIA1 GRIN2A MAPKAPK5 FAM83F MAP3K11 MAPK6 CDH5 ATP2B4 HSP90AA1 HSP90AB1	4.98e-03	873	102	11	GO:0019901
Domain	Ser/Thr_kinase_AS	CAMK1D PAK5 MAP3K20 CAMK1G MAPKAPK5 MYLK2 PHKG1 STK33 MAP3K11 MAPK6 EIF2AK2 PRKX	6.35e-07	357	103	12	IPR008271
Domain	S_TKc	CAMK1D PAK5 MAP3K20 CAMK1G MAPKAPK5 MYLK2 PHKG1 STK33 MAP3K11 MAPK6 EIF2AK2 PRKX	6.74e-07	359	103	12	SM00220
Domain	PROTEIN_KINASE_ST	CAMK1D PAK5 MAP3K20 CAMK1G MAPKAPK5 MYLK2 PHKG1 STK33 MAP3K11 MAPK6 EIF2AK2 PRKX	7.36e-07	362	103	12	PS00108
Domain	Kinase-like_dom	CAMK1D PAK5 MAP3K20 RIOK3 CAMK1G MAPKAPK5 MYLK2 PHKG1 PI4KB STK33 MAP3K11 MAPK6 EIF2AK2 PRKX	1.63e-06	542	103	14	IPR011009
Domain	Ca/CaM-dep_Ca-dep_prot_Kinase	CAMK1D CAMK1G MAPKAPK5 MYLK2 PHKG1 STK33	2.20e-06	69	103	6	IPR020636
Domain	Prot_kinase_dom	CAMK1D PAK5 MAP3K20 RIOK3 CAMK1G MAPKAPK5 MYLK2 PHKG1 STK33 MAP3K11 MAPK6 EIF2AK2 PRKX	2.90e-06	489	103	13	IPR000719
Domain	PROTEIN_KINASE_DOM	CAMK1D PAK5 MAP3K20 RIOK3 CAMK1G MAPKAPK5 MYLK2 PHKG1 STK33 MAP3K11 MAPK6 EIF2AK2 PRKX	3.17e-06	493	103	13	PS50011
Domain	Pkinase	CAMK1D PAK5 CAMK1G MAPKAPK5 MYLK2 PHKG1 STK33 MAP3K11 MAPK6 EIF2AK2 PRKX	8.20e-06	381	103	11	PF00069
Domain	PROTEIN_KINASE_ATP	CAMK1D PAK5 MAP3K20 CAMK1G MAPKAPK5 MYLK2 PHKG1 STK33 MAP3K11 MAPK6 EIF2AK2 PRKX	8.50e-06	459	103	12	PS00107
Domain	Protein_kinase_ATP_BS	CAMK1D PAK5 CAMK1G MYLK2 PHKG1 STK33 MAP3K11 MAPK6 EIF2AK2 PRKX	4.64e-05	379	103	10	IPR017441
Domain	DBINO	SMARCA5 INO80	9.00e-05	3	103	2	PF13892
Domain	DBINO	SMARCA5 INO80	9.00e-05	3	103	2	IPR020838
Domain	Heat_shock_protein_90_CS	HSP90AA1 HSP90AB1	9.00e-05	3	103	2	IPR019805
Domain	Tscrpt_reg_Myc_N	MYCL MYCLP1	1.79e-04	4	103	2	IPR012682
Domain	Tscrpt_reg_Myc	MYCL MYCLP1	1.79e-04	4	103	2	IPR002418
Domain	Hsp90_fam	HSP90AA1 HSP90AB1	1.79e-04	4	103	2	IPR001404
Domain	Hsp90_N	HSP90AA1 HSP90AB1	1.79e-04	4	103	2	IPR020575
Domain	Myc_N	MYCL MYCLP1	1.79e-04	4	103	2	PF01056
Domain	HSP90	HSP90AA1 HSP90AB1	1.79e-04	4	103	2	PF00183
Domain	HSP90	HSP90AA1 HSP90AB1	1.79e-04	4	103	2	PS00298
Domain	FN3	MPL FNDC3B PTPRM CNTN3 IGSF9 IL5RA	8.24e-04	199	103	6	PS50853
Domain	FN3_dom	MPL FNDC3B PTPRM CNTN3 IGSF9 IL5RA	1.06e-03	209	103	6	IPR003961
Domain	DAGK_acc	DGKA DGKK	1.32e-03	10	103	2	PF00609
Domain	Diacylglycerol_kin_accessory	DGKA DGKK	1.32e-03	10	103	2	IPR000756
Domain	DAGKa	DGKA DGKK	1.32e-03	10	103	2	SM00045
Domain	PH	PLEKHF1 MCF2 PLEKHA6 DGKK PLEKHA5 AKAP13	1.69e-03	229	103	6	PF00169
Domain	fn3	MPL FNDC3B PTPRM CNTN3 IGSF9	2.04e-03	162	103	5	PF00041
Domain	DAGKc	DGKA DGKK	2.62e-03	14	103	2	SM00046
Domain	Diacylglycerol_kinase_cat_dom	DGKA DGKK	3.02e-03	15	103	2	IPR001206
Domain	DAGK_cat	DGKA DGKK	3.02e-03	15	103	2	PF00781
Domain	DAGK	DGKA DGKK	3.02e-03	15	103	2	PS50146
Domain	FN3	MPL FNDC3B PTPRM CNTN3 IGSF9	3.62e-03	185	103	5	SM00060
Domain	Gal_mutarotase_SF_dom	MAN2A1 SI	3.88e-03	17	103	2	IPR011013
Domain	NAD/diacylglycerol_kinase	DGKA DGKK	3.88e-03	17	103	2	IPR016064
Domain	Iontro_rcpt	GRIA1 GRIN2A	4.35e-03	18	103	2	IPR001320
Domain	Lig_chan-Glu_bd	GRIA1 GRIN2A	4.35e-03	18	103	2	PF10613
Domain	Iono_rcpt_met	GRIA1 GRIN2A	4.35e-03	18	103	2	IPR001508
Domain	Glu/Gly-bd	GRIA1 GRIN2A	4.35e-03	18	103	2	IPR019594
Domain	Lig_chan-Glu_bd	GRIA1 GRIN2A	4.35e-03	18	103	2	SM00918
Domain	Lig_chan	GRIA1 GRIN2A	4.35e-03	18	103	2	PF00060
Domain	PBPe	GRIA1 GRIN2A	4.35e-03	18	103	2	SM00079
Domain	HATPase_c	HSP90AA1 HSP90AB1	4.35e-03	18	103	2	SM00387
Domain	PH	PLEKHF1 MCF2 PLEKHA6 DGKK PLEKHA5 AKAP13	4.42e-03	278	103	6	SM00233
Domain	PH_DOMAIN	PLEKHF1 MCF2 PLEKHA6 DGKK PLEKHA5 AKAP13	4.50e-03	279	103	6	PS50003
Domain	PH_domain	PLEKHF1 MCF2 PLEKHA6 DGKK PLEKHA5 AKAP13	4.57e-03	280	103	6	IPR001849
Domain	HATPase_c	HSP90AA1 HSP90AB1	4.84e-03	19	103	2	PF02518
Domain	DH_1	MCF2 ARHGEF10 AKAP13	5.09e-03	63	103	3	PS00741
Domain	ZF_DAG_PE_1	DGKA DGKK AKAP13	5.32e-03	64	103	3	PS00479
Domain	ZF_DAG_PE_2	DGKA DGKK AKAP13	5.32e-03	64	103	3	PS50081
Domain	-	HSP90AA1 HSP90AB1	5.36e-03	20	103	2	3.30.565.10
Domain	C1	DGKA DGKK AKAP13	5.55e-03	65	103	3	SM00109
Domain	Ig-like_fold	MPL FNDC3B ADAMTSL3 PKHD1L1 PTGFRN PTPRM IGHG3 CNTN3 IGSF9 IL5RA	5.59e-03	706	103	10	IPR013783
Domain	PE/DAG-bd	DGKA DGKK AKAP13	5.80e-03	66	103	3	IPR002219
Pathway	KEGG_MEDICUS_REFERENCE_CA2_CAM_CAMK_SIGNALING_PATHWAY	CAMK1D CAMK1G MYLK2 PHKG1	3.00e-06	19	77	4	M47957
Pubmed	A human MAP kinase interactome.	PACSIN1 PAK5 PLEKHA6 LCP2 MAPKAPK5 MAP3K11 PLEKHA5 AKAP13 MAPK6 MOB4 HSP90AA1 HSP90AB1	3.25e-08	486	106	12	20936779
Pubmed	Reelin signaling facilitates maturation of CA1 glutamatergic synapses.	RELN GRIA1 GRIN2A	2.74e-07	5	106	3	17229826
Pubmed	Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signaling.	MAP3K11 HSP90AA1 HSP90AB1	2.74e-07	5	106	3	15001580
Pubmed	Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33.	STK33 HSP90AA1 HSP90AB1	1.52e-06	8	106	3	22451720
Pubmed	The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons.	CD37 HSP90AA1 HSP90AB1	2.28e-06	9	106	3	16280321
Pubmed	Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.	ATXN2L HECTD3 PAK5 OLA1 EIF4ENIF1 HSP90AA1 HSP90AB1	8.35e-06	236	106	7	36339263
Pubmed	Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway.	MAPKAPK5 MAPK6	9.20e-06	2	106	2	15577943
Pubmed	Expression of hsp90 and cyclin D1 in human breast cancer.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	10376793
Pubmed	Macrophage activation and Fcgamma receptor-mediated signaling do not require expression of the SLP-76 and SLP-65 adaptors.	BLNK LCP2	9.20e-06	2	106	2	14694181
Pubmed	Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	33179566
Pubmed	Regulation of embryonic stem cell pluripotency by heat shock protein 90.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	22696450
Pubmed	The human L-myc gene encodes multiple nuclear phosphoproteins from alternatively processed mRNAs.	MYCL MYCLP1	9.20e-06	2	106	2	3054516
Pubmed	Role of major NMDA or AMPA receptor subunits in MK-801 potentiation of ethanol intoxication.	GRIA1 GRIN2A	9.20e-06	2	106	2	18565157
Pubmed	Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	22895790
Pubmed	Hsp90 is cleaved by reactive oxygen species at a highly conserved N-terminal amino acid motif.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	22848402
Pubmed	Expression of Hsp90 chaperone [corrected] proteins in human tumor tissue.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	19576239
Pubmed	A mouse tumor-specific transplantation antigen is a heat shock-related protein.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	3458168
Pubmed	Mechanism of dimer formation of the 90-kDa heat-shock protein.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	7588731
Pubmed	Murine 86- and 84-kDa heat shock proteins, cDNA sequences, chromosome assignments, and evolutionary origins.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	2925609
Pubmed	Heat-shock proteins, Hsp84 and Hsp86, of mice and men: two related genes encode formerly identified tumour-specific transplantation antigens.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	2469626
Pubmed	Cloning and analysis of a human 86-kDa heat-shock-protein-encoding gene.	HSP90AA1 HSP90AA2P	9.20e-06	2	106	2	2591742
Pubmed	Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing.	MYCL MYCLP1	9.20e-06	2	106	2	2827002
Pubmed	HSP90 expression and early recurrence in gastroenteropancreatic neuroendocrine tumors: Potential for a novel therapeutic target.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	33080545
Pubmed	Circulating Hsp90 Isoform Levels in Overweight and Obese Children and the Relation to Nonalcoholic Fatty Liver Disease: Results from a Cross-Sectional Study.	HSP90AA2P HSP90AB1	9.20e-06	2	106	2	31885746
Pubmed	Heat shock protein 90 facilitates SARS-CoV-2 structural protein-mediated virion assembly and promotes virus-induced pyroptosis.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	37011862
Pubmed	Cell surface heparan sulfate proteoglycans are involved in the binding of Hsp90α and Hsp90β to the cell plasma membrane.	HSP90AA2P HSP90AB1	9.20e-06	2	106	2	26651243
Pubmed	Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	36270993
Pubmed	Hsp90 regulation of fibroblast activation in pulmonary fibrosis.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	28239659
Pubmed	Proximity interactome of lymphatic VE-cadherin reveals mechanisms of junctional remodeling and reelin secretion.	RELN CDH5	9.20e-06	2	106	2	39232006
Pubmed	Despite their structural similarities, the cytosolic isoforms of human Hsp90 show different behaviour in thermal unfolding due to their conformation: An FTIR study.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	37028636
Pubmed	Proliferation, migration, and resistance to oxidative and thermal stresses of HT1080 cells with knocked out genes encoding Hsp90α and Hsp90β.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	37406487
Pubmed	Expression and therapeutic relevance of heat-shock protein 90 in pancreatic endocrine tumors.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	22194440
Pubmed	Circadian expression of 86- and 84-kDa heat shock proteins in the mouse suprachiasmatic nucleus.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	18480550
Pubmed	Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	22841823
Pubmed	Substitution of only two residues of human Hsp90alpha causes impeded dimerization of Hsp90beta.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	18347946
Pubmed	Heat shock protein 90 overexpression independently predicts inferior disease-free survival with differential expression of the alpha and beta isoforms in gastrointestinal stromal tumors.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	19047110
Pubmed	Conserved conformational changes in the ATPase cycle of human Hsp90.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	18400751
Pubmed	Inhibition of RPE cell sterile inflammatory responses and endotoxin-induced uveitis by a cell-impermeable HSP90 inhibitor.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	22019372
Pubmed	The fibrin-derived peptide Bbeta15-42 protects the myocardium against ischemia-reperfusion injury.	FGB CDH5	9.20e-06	2	106	2	15723073
Pubmed	Two dimensional Blue Native-/SDS-PAGE analysis of SLP family adaptor protein complexes.	BLNK LCP2	9.20e-06	2	106	2	16356554
Pubmed	Heat shock protein HSP86 expression during mouse embryo development, especially in the germ-line.	HSP90AA1 HSP90AB1	9.20e-06	2	106	2	12136260
Pubmed	The HSP90 family of genes in the human genome: insights into their divergence and evolution.	HSP90AA1 HSP90AA2P HSP90AB1	1.50e-05	16	106	3	16269234
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	SMARCA5 KDM5A ANAPC1 PWP2 ANKRD11 HSP90AA1 HSP90AB1	2.09e-05	272	106	7	31010829
Pubmed	BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2.	RELN GRIA1 GRIN2A	2.17e-05	18	106	3	12588844
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	ATXN2L SMARCA5 MAP3K20 PLEKHA6 ZC3H4 MAP3K11 PLEKHA5 AKAP13 HSP90AB1	2.45e-05	503	106	9	16964243
Pubmed	The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR.	EIF2AK2 HSP90AA1	2.76e-05	3	106	2	11447118
Pubmed	A pilot proteomic study with a prospective cohort suspected to develop preeclampsia.	RELN FGB	2.76e-05	3	106	2	32472113
Pubmed	Molecular recognition via coupled folding and binding in a TPR domain.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	15713458
Pubmed	Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	2492519
Pubmed	Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84).	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	1406681
Pubmed	Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking.	PACSIN1 PAK5	2.76e-05	3	106	2	22371566
Pubmed	Mammalian CHORD-containing protein 1 is a novel heat shock protein 90-interacting protein.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	15642353
Pubmed	Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	20226818
Pubmed	PLEKHA5, PLEKHA6, and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to the cell periphery and regulate copper homeostasis.	PLEKHA6 PLEKHA5	2.76e-05	3	106	2	34613798
Pubmed	Modulation of Akt kinase activity by binding to Hsp90.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	10995457
Pubmed	The regulatory mechanism of extracellular Hsp90{alpha} on matrix metalloproteinase-2 processing and tumor angiogenesis.	HSP90AA1 HSP90AA2P	2.76e-05	3	106	2	20937816
Pubmed	Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	18550790
Pubmed	Regulator of G-Protein Signaling 4 (RGS4) Controls Morphine Reward by Glutamate Receptor Activation in the Nucleus Accumbens of Mouse Brain.	GRIA1 GRIN2A	2.76e-05	3	106	2	29754475
Pubmed	N-terminal domain of human Hsp90 triggers binding to the cochaperone p23.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	21183720
Pubmed	Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	29386344
Pubmed	Hsp90 stabilizes Cdc25A and counteracts heat shock-mediated Cdc25A degradation and cell-cycle attenuation in pancreatic carcinoma cells.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	22843495
Pubmed	HSP90 affects the stability of BMAL1 and circadian gene expression.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	24682203
Pubmed	PMCA4 gene expression is regulated by the androgen receptor in the mouse testis during spermatogenesis.	PLEKHA5 ATP2B4	2.76e-05	3	106	2	33355366
Pubmed	Mammalian heat shock factor 1 is essential for oocyte meiosis and directly regulates Hsp90alpha expression.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	19158073
Pubmed	Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	22849407
Pubmed	Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5.	MAPKAPK5 MAPK6	2.76e-05	3	106	2	16973613
Pubmed	Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness.	HSP90AA1 HSP90AA2P	2.76e-05	3	106	2	15146192
Pubmed	Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	16531226
Pubmed	Heat Shock Protein 90 Family Isoforms as Prognostic Biomarkers and Their Correlations with Immune Infiltration in Breast Cancer.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	33145341
Pubmed	Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	19996089
Pubmed	HSP-enriched properties of extracellular vesicles involve survival of metastatic oral cancer cells.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	29768689
Pubmed	Hsp90 activity is necessary to acquire a proper neuronal polarization.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	24286867
Pubmed	Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	15358771
Pubmed	The significance of HSP90AA1, HSP90AB1 and HSP90B1 gene polymorphisms in a Turkish population with non-small cell lung cancer.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	24511009
Pubmed	Chaperone ligand-discrimination by the TPR-domain protein Tah1.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	18412542
Pubmed	Interaction of pro-apoptotic protein HGTD-P with heat shock protein 90 is required for induction of mitochondrial apoptotic cascades.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	16698020
Pubmed	HSP90 regulates cell survival via inositol hexakisphosphate kinase-2.	HSP90AA1 HSP90AB1	2.76e-05	3	106	2	18195352
Pubmed	SLP-65 signal transduction requires Src homology 2 domain-mediated membrane anchoring and a kinase-independent adaptor function of Syk.	BLNK LCP2	2.76e-05	3	106	2	17681949
Pubmed	Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5.	MAPKAPK5 MAPK6	2.76e-05	3	106	2	18720373
Pubmed	Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex.	MYLK2 HSP90AA1 HSP90AB1	3.52e-05	21	106	3	23428871
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SART3 FNDC3B MAN2A1 GEMIN2 KDM5A MAP3K20 INO80 OLA1 WRAP53 MYLK2 EIF4ENIF1 ANAPC1 PWP2 ANKRD11 EIF2AK2	4.91e-05	1497	106	15	31527615
Pubmed	HSP90 promotes radioresistance of cervical cancer cells via reducing FBXO6-mediated CD147 polyubiquitination.	HSP90AA1 HSP90AB1	5.50e-05	4	106	2	35043518
Pubmed	Functional requirement of p23 and Hsp90 in telomerase complexes.	HSP90AA1 HSP90AB1	5.50e-05	4	106	2	10197982
Pubmed	The levels of retinoic acid-inducible gene I are regulated by heat shock protein 90-alpha.	HSP90AA1 HSP90AA2P	5.50e-05	4	106	2	19234166
Pubmed	Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes.	BLNK LCP2	5.50e-05	4	106	2	11487585
Pubmed	Mapping of the gene family for human heat-shock protein 90 alpha to chromosomes 1, 4, 11, and 14.	HSP90AA1 HSP90AA2P	5.50e-05	4	106	2	1740332
Pubmed	Myc and Max: molecular evolution of a family of proto-oncogene products and their dimerization partner.	MYCL MYCLP1	5.50e-05	4	106	2	7479755
Pubmed	The E3 ligase CHIP mediates ubiquitination and degradation of mixed-lineage kinase 3.	MAP3K11 HSP90AA1	5.50e-05	4	106	2	24912674
Pubmed	Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells.	HSP90AA1 HSP90AB1	5.50e-05	4	106	2	16394098
Pubmed	Replicative verification of susceptibility genes previously identified from families with segregating developmental dysplasia of the hip.	TENM3 ATP2B4	5.50e-05	4	106	2	34174923
Pubmed	HECTD3 Mediates an HSP90-Dependent Degradation Pathway for Protein Kinase Clients.	HECTD3 HSP90AA1	5.50e-05	4	106	2	28636940
Pubmed	Cloning and characterization of a family of proteins associated with Mpl.	MPL ATXN2L	5.50e-05	4	106	2	11784712
Pubmed	Hsp90-Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis.	HSP90AA1 HSP90AB1	5.50e-05	4	106	2	15782121
Pubmed	Regulation of proto-oncogenic dbl by chaperone-controlled, ubiquitin-mediated degradation.	MCF2 HSP90AA1	5.50e-05	4	106	2	17178836
Pubmed	Extracellular heat shock protein 90 binding to TGFβ receptor I participates in TGFβ-mediated collagen production in myocardial fibroblasts.	HSP90AA1 HSP90AB1	5.50e-05	4	106	2	27418101
Pubmed	Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2.	HSP90AA1 HSP90AB1	5.50e-05	4	106	2	12482853
Pubmed	Hsp90 interactions and acylation target the G protein Galpha 12 but not Galpha 13 to lipid rafts.	HSP90AA1 HSP90AB1	5.50e-05	4	106	2	12117999
Pubmed	Combination of pan-histone deacetylase inhibitor and autophagy inhibitor exerts superior efficacy against triple-negative human breast cancer cells.	HSP90AA1 HSP90AB1	5.50e-05	4	106	2	22367781
Pubmed	Involvement of heat-shock protein 90 in the interleukin-6-mediated signaling pathway through STAT3.	HSP90AA1 HSP90AB1	5.50e-05	4	106	2	12559950
Pubmed	Stabilization of Notch1 by the Hsp90 Chaperone Is Crucial for T-Cell Leukemogenesis.	HSP90AA1 HSP90AB1	5.50e-05	4	106	2	28143869
Interaction	UNC45B interactions	GRIA1 PWP2 HSP90AA1 HSP90AB1	4.56e-06	22	104	4	int:UNC45B
Cytoband	Ensembl 112 genes in cytogenetic band chr1p34	MPL MYCL HECTD3 ADPRS SF3A3 IPO13	6.54e-05	294	106	6	chr1p34
GeneFamily	Heat shock 90kDa proteins	HSP90AA1 HSP90AB1	1.34e-04	5	67	2	586
GeneFamily	Fibronectin type III domain containing	MPL FNDC3B PTPRM CNTN3 IGSF9	3.16e-04	160	67	5	555
GeneFamily	EF-hand domain containing\|Diacylglycerol kinases	DGKA DGKK	5.97e-04	10	67	2	1178
GeneFamily	Immunoglobulin like domain containing	ADAMTSL3 PTGFRN PTPRM CNTN3 IGSF9	7.44e-04	193	67	5	594
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	MCF2 ARHGEF10 AKAP13	1.88e-03	66	67	3	722
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	ADAMTSL3 PTPRM CNTN3 IGSF9	3.00e-03	161	67	4	593
GeneFamily	Neuroblastoma breakpoint family	NBPF12 NBPF1	3.25e-03	23	67	2	662
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K20 MAP3K11	3.54e-03	24	67	2	654
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN ERO1B BLNK GPATCH2 IGHG3 CD37 MAPK6	1.00e-07	157	106	7	6730b775308f45a2f3946016bdbb7f8e5b5efe49
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	RIOK3 IGHG3 ANKRD11 AKAP13 EIF2AK2 HSP90AA1 HSP90AB1	5.19e-07	200	106	7	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	TCGA-Brain\|World / Sample_Type by Project: Shred V9	TTYH1 BEST3 GRIA1 RFTN2 PHKG1 AMER2	3.32e-06	170	106	6	f78e360a6a44d599ec0d207cba4704e50aa314f8
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_2\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	SMARCA5 BEST3 RFTN2 OLA1 STK33 PRKX	4.47e-06	179	106	6	d95367d689732ab2653e8d70d8d8e5eb15ae6eef
ToppCell	droplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL FNDC3B PACSIN1 FAM83F ARHGEF10 CDH5	4.47e-06	179	106	6	d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL PACSIN1 BLNK FAM83F ARHGEF10 CDH5	4.77e-06	181	106	6	fb64da1dde37fe6ba7de2586cd58848ac1974f24
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN CACNA2D2 BEST3 LCP2 PTPRM PRKX	5.24e-06	184	106	6	7f6c8912677764d438ab0555faca344d74c2f483
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	FNDC3B RELN PRODH2 TENM3 PTPRM PLEKHA5	5.41e-06	185	106	6	1d874608aa2062024323512f68889219471b2f00
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN CACNA2D2 LCP2 TENM3 PTPRM PRKX	5.75e-06	187	106	6	85f1678338a47d91e296f0620d4887f057eb7e70
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN CACNA2D2 ADAMTSL3 TENM3 PTPRM PRKX	6.89e-06	193	106	6	d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FNDC3B CAMK1D PLEKHA6 PTPRM ANKRD11 AKAP13	6.89e-06	193	106	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN CACNA2D2 ADAMTSL3 TENM3 PTPRM PRKX	6.89e-06	193	106	6	2c15186d15545804cc262da9137ab825609d4b2c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN CACNA2D2 ADAMTSL3 TENM3 PTPRM PRKX	6.89e-06	193	106	6	010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN CACNA2D2 ADAMTSL3 TENM3 PTPRM PRKX	6.89e-06	193	106	6	3ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN CACNA2D2 ADAMTSL3 TENM3 PTPRM PRKX	6.89e-06	193	106	6	e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN CACNA2D2 ADAMTSL3 TENM3 PTPRM PRKX	6.89e-06	193	106	6	658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-MGE2\|World / Primary Cells by Cluster	RELN CACNA2D2 GRIA1 GRIN2A SLC7A14 PTPRM	7.09e-06	194	106	6	b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-MGE2-10\|World / Primary Cells by Cluster	RELN CACNA2D2 GRIA1 GRIN2A SLC7A14 PTPRM	7.09e-06	194	106	6	81e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN CACNA2D2 ADAMTSL3 TENM3 PTPRM PRKX	7.09e-06	194	106	6	1bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCell	facs-Trachea\|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FNDC3B ADAMTSL3 TENM3 HAS1 MAPK6 HSP90AA1	7.52e-06	196	106	6	8209f2b0f7efebaaf81d642d18a1aee8a9a8dcf6
ToppCell	facs-Trachea\|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC3B ADAMTSL3 TENM3 HAS1 MAPK6 HSP90AA1	7.52e-06	196	106	6	34020d6553309daa269dff05de0a8567211ea4d2
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ERO1B BLNK BEST3 CD37 HSP90AA1 HSP90AB1	7.97e-06	198	106	6	5f465cf5c7493e32d9afe9e9d05757d0a95acc33
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ERO1B BLNK BEST3 CD37 HSP90AA1 HSP90AB1	7.97e-06	198	106	6	77ce3fe1ab161c0faf8987e73a64ab61294b9255
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pre_B_progenitor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CCDC69 ERO1B BEST3 CD37 ANKRD11 HSP90AA1	8.20e-06	199	106	6	dd94e42b62af7cbd69c472681d3c758552694ae2
ToppCell	Control_saline-Hematopoietic_Myeloid-Granulocytic_cells\|Control_saline / Treatment groups by lineage, cell group, cell type	LCP2 AMER2 LRRC25 CD37 HAS1 IL5RA	8.20e-06	199	106	6	a4d6525e70de39802ff9fdef0d877c4463a6200d
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN CACNA2D2 ADAMTSL3 TENM3 PTPRM PRKX	8.44e-06	200	106	6	858421b91f5207b7934b5c219752cb9322a3da31
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN CACNA2D2 ADAMTSL3 TENM3 PTPRM PRKX	8.44e-06	200	106	6	a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCell	Sepsis-Int-URO-Lymphocyte-B-B_intermediate\|Int-URO / Disease, condition lineage and cell class	BLNK RFTN2 PKHD1L1 ARHGEF10 IGHG3 CD37	8.44e-06	200	106	6	221dd8d8851c47f2202ba848de3a041b17b1db3f
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN CACNA2D2 ADAMTSL3 TENM3 PTPRM PRKX	8.44e-06	200	106	6	2131c8e7fa054b79906eaf60536da892438b09cd
ToppCell	P03-Hematopoietic-Immune-immune_cell_unspecified\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MPL BLNK LCP2 LRRC25 CD37	2.88e-05	149	106	5	43d756f81d532b5c7f2306e6af9d072d496cbc8e
ToppCell	P03-Hematopoietic-Immune\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MPL BLNK LCP2 LRRC25 CD37	2.88e-05	149	106	5	1c5a2572741c47246d455c865e8e1677c9f49598
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MCF2 ZNF510 VIPAS39 IPO13 ATP2B4	3.48e-05	155	106	5	5687416773809b8c478567bc54310af102b3029a
ToppCell	368C-Lymphocytic-Plasma_cell-\|368C / Donor, Lineage, Cell class and subclass (all cells)	PACSIN1 BLNK PKHD1L1 AMER2 IGHG3	4.30e-05	162	106	5	c21a54310b239d999bbc9d8fb5e8fda16e0bc336
ToppCell	facs-Lung-Endomucin_-18m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1B BLNK VIPAS39 CD37 IL5RA	4.30e-05	162	106	5	e81dec1db8e5a808d96e58410c91961e5d065c94
ToppCell	368C-Lymphocytic-Plasma_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	PACSIN1 BLNK PKHD1L1 AMER2 IGHG3	4.30e-05	162	106	5	f945688815229c8386cbcbf46deee7df316fa8d3
ToppCell	facs-Lung-Endomucin_-18m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1B BLNK VIPAS39 CD37 IL5RA	4.30e-05	162	106	5	d19b469f64c9064cfb82dadb6c8135e28949a02a
ToppCell	facs-Lung-Endomucin_-18m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1B BLNK VIPAS39 CD37 IL5RA	4.30e-05	162	106	5	10c2aa047f33f48e4abe676236bbdb593079dd1d
ToppCell	facs-Heart-RA-18m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1B BLNK AMER2 CD37 IL5RA	4.83e-05	166	106	5	fc2cf67311c86fda75b35fcd4768b6f6f14c59d0
ToppCell	facs-Heart-RA-18m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1B BLNK AMER2 CD37 IL5RA	4.83e-05	166	106	5	33a6876d06e26176135a73a77c19e634ec53f7ce
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1B BLNK CD37 DGKK IL5RA	4.97e-05	167	106	5	691f3589de0f8c13f9137812cfa9040c07d237b4
ToppCell	Immune_cells-Dendritic_cells\|World / Lineage and Cell class	MYCL PACSIN1 BLNK CD37 CDH5	5.41e-05	170	106	5	094dc211d80c89ecb1010855f1fe6eeb71bf0e20
ToppCell	facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL FNDC3B PACSIN1 ARHGEF10 CDH5	5.56e-05	171	106	5	6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCell	facs-Marrow-T-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL FNDC3B PACSIN1 ARHGEF10 CDH5	5.56e-05	171	106	5	e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCell	ASK428-Immune-B_cell\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	CAMK1D BLNK ARHGEF10 IGHG3 CD37	6.04e-05	174	106	5	b5a7a612a515736cf3489afd0f6ad2054d54526f
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL PACSIN1 FAM83F PLA2G4F CDH5	6.37e-05	176	106	5	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL PACSIN1 FAM83F PLA2G4F CDH5	6.37e-05	176	106	5	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMARCA5 ANKRD11 CDH5 HSP90AA1 HSP90AB1	6.72e-05	178	106	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL PACSIN1 BLNK ARHGEF10 CDH5	6.90e-05	179	106	5	1757b9f3f4c634277a67c4f5a39d27d6b4937073
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Pre-B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC69 BLNK BEST3 STK33 CD37	6.90e-05	179	106	5	dc0b806904ef4c2f74f34ade2b1c0d6893f3b2ec
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL PACSIN1 BLNK ARHGEF10 CDH5	7.09e-05	180	106	5	df60970520fba2ac0639faa54096766d07418ca4
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL PACSIN1 BLNK ARHGEF10 CDH5	7.09e-05	180	106	5	64f01494a4052186773720e10b4e7c724ff94547
ToppCell	PCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CCDC69 CAMK1D BLNK BEST3 CD37	7.27e-05	181	106	5	51e4d6bfdbf414d8e30aee2e6f7492f4f7f54373
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL PACSIN1 BLNK ARHGEF10 CDH5	7.47e-05	182	106	5	33afbb7c4352b03266501b1f4f0e751c12c7350d
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RELN GRIA1 PKHD1L1 TENM3 CDH5	7.66e-05	183	106	5	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	droplet-Thymus-nan-18m-Myeloid-Plasma_cells_and_B_cells\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC3B RELN ERO1B IGSF9 IL5RA	7.66e-05	183	106	5	ffb1bbbccb34d1a7e99872611f497450039d5019
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LCP2 ADAMTSL3 TENM3 PTPRM PRKX	7.86e-05	184	106	5	23515c28e1f42aab29cef9e5b4a7f45bda7f5520
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-Pre-B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC69 ERO1B BLNK BEST3 CD37	8.06e-05	185	106	5	0fa7970709dc957dea95fabbd83263a0335babd5
ToppCell	PCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CCDC69 BLNK BEST3 LCP2 CD37	8.06e-05	185	106	5	8fc357ee041bfd588986730a52ea2021b5f88941
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL PACSIN1 BLNK ARHGEF10 CDH5	8.06e-05	185	106	5	65dcb0a7ee64990a34a87c167b44497107f035ee
ToppCell	metastatic_Brain-B_lymphocytes\|metastatic_Brain / Location, Cell class and cell subclass	BLNK PKHD1L1 IGHG3 CD37 IL5RA	8.06e-05	185	106	5	153b82dc5ace03f84dc82d724d56bdc93aa020df
ToppCell	droplet-Bladder-nan-24m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 RELN SLC7A14 PTPRM CDH5	8.06e-05	185	106	5	90caab8d9361a541c5d5121c97c3f1cdffeeae4a
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TTYH1 ISM1 GRIA1 ADAMTSL3 TENM3	8.27e-05	186	106	5	4d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCell	Anterior_Cingulate_gyrus_(CgG)\|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIA1 NBPF1 TENM3 PRMT2 ATP2B4	8.27e-05	186	106	5	32af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ERO1B SLC7A14 TENM3 AKAP13	8.70e-05	188	106	5	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_2\|Striatum / BrainAtlas - Mouse McCarroll V32	MPL PLEKHF1 KIF24 FCGBP	8.87e-05	98	106	4	7a62a77ca83153dacff4d02d6e32104227d0980d
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocye.Tnr.Pdgfa_(Pdgfa)\|Striatum / BrainAtlas - Mouse McCarroll V32	MPL PLEKHF1 KIF24 FCGBP	8.87e-05	98	106	4	26250ea4171a0557a67505839cf79d3fe4d9d41a
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr\|Striatum / BrainAtlas - Mouse McCarroll V32	MPL PLEKHF1 KIF24 FCGBP	8.87e-05	98	106	4	42875d16ae9fcbaf988cd71be82568f2f862f2dd
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA2D2 ADAMTSL3 TENM3 PTPRM PRKX	8.92e-05	189	106	5	06c44746fa4f02e6e2b3b635cdf2d8dfef3754d3
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA2D2 BEST3 TENM3 PTPRM PRKX	9.14e-05	190	106	5	26843ec1d19ac85a50990705353b802745d33e4d
ToppCell	PSB-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAN2A1 CACNA2D2 PAK5 BEST3 TENM3	9.37e-05	191	106	5	8f4637e801554e2343b974fe7794f01dd2151418
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA2D2 ADAMTSL3 TENM3 PTPRM PRKX	9.37e-05	191	106	5	9c0ee270209b02043393416ecc9a81ddedfbb8b6
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B PTPRM ANKRD11 PLEKHA5 AKAP13	9.60e-05	192	106	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA2D2 BEST3 TENM3 PTPRM PRKX	9.84e-05	193	106	5	4979862c0c16e6b4baa4c79894f1d237c861f5a5
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN CACNA2D2 TENM3 PTPRM PRKX	9.84e-05	193	106	5	2189da4b727e25e62669d7b9257f06493be21a27
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN GRIN2A PTGFRN ARHGEF10 CDH5	9.84e-05	193	106	5	2483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN CACNA2D2 ADAMTSL3 TENM3 PRKX	1.01e-04	194	106	5	83863da11dfbe59b2d0a2c08db40b537c150588c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC69 RELN PKHD1L1 PTPRM CDH5	1.01e-04	194	106	5	ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	MAP3K20 STK33 PLEKHA5 AKAP13 ATP2B4	1.03e-04	195	106	5	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FNDC3B BLNK PKHD1L1 IGHG3 IL5RA	1.03e-04	195	106	5	fb3d6a3b10aedc7fdd9789b2c47b4e80fa8e411f
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-B-B_cell\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	BLNK PKHD1L1 SLC7A14 IGHG3 CD37	1.06e-04	196	106	5	f37ffb916480281e5905733ac304102dd2e0c05f
ToppCell	severe_COVID-19-B_memory\|severe_COVID-19 / disease group, cell group and cell class (v2)	CAMK1D BLNK IGHG3 CD37 HSP90AB1	1.06e-04	196	106	5	c6e00cb59a88b9903cca233cefe05f80c5ea4153
ToppCell	medial-Hematologic-Myeloid_Dendritic_Type_1\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MYCL CAMK1D CAMK1G RS1 FGB	1.08e-04	197	106	5	5bd2f32137fd849931e52093d630d2e7e27daf4f
ToppCell	medial-Hematologic-Myeloid_Dendritic_Type_1-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MYCL CAMK1D CAMK1G RS1 FGB	1.08e-04	197	106	5	d9baa0be469fd8737a74b5078d30ce7d66759160
ToppCell	medial-2-Hematologic-Myeloid_Dendritic_Type_1\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MYCL CAMK1D CAMK1G RS1 FGB	1.08e-04	197	106	5	3c1147857de6a7ab6b0cf77f5a6364d4c8669693
ToppCell	severe_COVID-19-B_intermediate\|severe_COVID-19 / disease group, cell group and cell class (v2)	CAMK1D BLNK IGHG3 CD37 HSP90AB1	1.08e-04	197	106	5	3ba64850b344cb24a4d20d64392a0b2752950d40
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-B-Plasmablast\|ICU-NoSEP / Disease, condition lineage and cell class	BLNK PKHD1L1 KIF24 IGHG3 STK33	1.08e-04	197	106	5	8f35f9741086a38f0e594dce0547b575946f52bb
ToppCell	Bronchus_Control_(B.)-Immune-TX-B_cells\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	PKHD1L1 IGHG3 CD37 HSP90AA1 HSP90AB1	1.11e-04	198	106	5	6231c44a909dd06f85c8210814e976a5f29148d0
ToppCell	LPS_IL1RA-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYCL PACSIN1 BLNK LRRC25 CD37	1.14e-04	199	106	5	f197ab861767ee06aa47b86c537fb3d8c2b2bc3e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	PAK5 GRIA1 AMER2 PRKX HSP90AA1	1.16e-04	200	106	5	84e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCell	Control_saline-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells\|Control_saline / Treatment groups by lineage, cell group, cell type	LCP2 LRRC25 CD37 HAS1 IL5RA	1.16e-04	200	106	5	58b25dc2d29e98354bfc8e8e161796c237c3dc23
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN CACNA2D2 TENM3 PTPRM PRKX	1.16e-04	200	106	5	347a510755374c6a66acee326565dfc447993f18
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T\|COVID-19_Severe / Disease, condition lineage and cell class	CACNA2D2 PLEKHF1 FCGBP DGKK ATP2B4	1.16e-04	200	106	5	f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCell	Neuronal-Inhibitory-iB\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CACNA2D2 BEST3 TENM3 PTPRM PRKX	1.16e-04	200	106	5	45ddc5ef2caa87ada88327b63ba9b150a6bb3aa5
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN CACNA2D2 CBY2 IGSF9	1.65e-04	115	106	4	ac73aa06e617ed791c6ae9e38189bac74188c27b
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte1_(20)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MPL LCP2 PKHD1L1 IL5RA	2.48e-04	128	106	4	a190aa5a6db9c4120f4667af40ac3da2f267d4da
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod-3\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	ERO1B GPATCH2 CBY2 MAPK6	3.21e-04	137	106	4	a1e34ebbeda3d5a4f14917282d44fcb4dcbf3133
ToppCell	LPS-IL1RA-Hematopoietic_Mast-Mast_cells-Mast-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CCDC69 PRODH2 CD37 IL5RA	3.40e-04	139	106	4	f1d1a51a79afdddc82e73cd29b3240e3e973db28
ToppCell	facs-Aorta-Heart-3m-Myeloid-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCF2 RIOK3 DGKK FGB	3.40e-04	139	106	4	22a769d5195ed761ef333ef542746e1ba617a698
ToppCell	facs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCF2 RIOK3 DGKK FGB	3.40e-04	139	106	4	292533e04178dd36d57377562077f9deb2cb9746
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RFTN2 PTGFRN KIF24 CDH5	3.68e-04	142	106	4	e160f35b3c18e77c4107fe96db5f56227c91785e
Drug	neotrehalose	MPL PACSIN1 SI GRIN2A CNTN3 EIF2AK2 HSP90AA1 HSP90AA2P HSP90AB1	6.66e-07	214	105	9	CID000001143
Drug	NSC330499	HSP90AA1 HSP90AA2P HSP90AB1	3.29e-06	7	105	3	CID000433447
Drug	phenyldichloroarsine	HSP90AA1 HSP90AA2P HSP90AB1	5.25e-06	8	105	3	CID000012762
Drug	benzoquinone	PACSIN1 SI GRIN2A EIF2AK2 ATP2B4 HSP90AA1 HSP90AA2P HSP90AB1	5.74e-06	209	105	8	CID000004650
Drug	5,8-quinolinedione	HSP90AA1 HSP90AA2P HSP90AB1	7.85e-06	9	105	3	CID000388306
Drug	Pu-3	HSP90AA1 HSP90AA2P HSP90AB1	1.53e-05	11	105	3	CID000448965
Drug	kainite	GRIA1 GRIN2A MAP3K11 AKAP13	2.00e-05	35	105	4	CID000164810
Drug	3-amino-5-chlorobenzoic acid	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID010986726
Drug	monocillin III	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID006478910
Drug	pochonin A	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID006478909
Drug	PU-H71	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID009549213
Drug	9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine	HSP90AA1 HSP90AB1	2.11e-05	2	105	2	DB02754
Drug	1uyc	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID000448969
Drug	PU-9	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID000448971
Drug	P u 0	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID000448974
Drug	2qf6	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID013373715
Drug	Geldanamycin	HSP90AA1 HSP90AB1	2.11e-05	2	105	2	DB02424
Drug	CHEBI:42139	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID011562562
Drug	2qfo	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID000600769
Drug	3eko	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID011160307
Drug	8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE	HSP90AA1 HSP90AB1	2.11e-05	2	105	2	DB07877
Drug	1uyi	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID005289232
Drug	4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL	HSP90AA1 HSP90AB1	2.11e-05	2	105	2	DB07594
Drug	NSC683666	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID005469153
Drug	H 64	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID006914564
Drug	SureCN4151355	HSP90AA1 HSP90AA2P	2.11e-05	2	105	2	CID015942101
Drug	Fenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A	ALKBH4 HECTD3 MAP3K20 DGKA WRAP53 AKAP13 PRKX	3.19e-05	193	105	7	3412_DN
Drug	Risperidone [106266-06-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A	CACNA2D2 PACSIN1 PLEKHF1 TENM3 PTPRM ATP2B4 IL5RA	3.52e-05	196	105	7	3508_UP
Drug	Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; HL60; HG-U133A	MYCL SMARCA5 GEMIN2 RIOK3 LCP2 POLR3F TOPORS	3.52e-05	196	105	7	1586_UP
Drug	Methapyrilene hydrochloride [135-23-9]; Up 200; 13.4uM; HL60; HG-U133A	GEMIN2 RIOK3 POLR3F PRODH2 ANKRD11 AKAP13 TOPORS	3.75e-05	198	105	7	1588_UP
Drug	Tranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; MCF7; HT_HG-U133A	MYCL MAP3K20 ZNF510 PLEKHA6 TENM3 ATP2B4 IL5RA	4.00e-05	200	105	7	5996_DN
Drug	AC1L9PMA	HSP90AA1 HSP90AA2P HSP90AB1	4.17e-05	15	105	3	CID000451405
Drug	pochonin D	HSP90AA1 HSP90AA2P	6.30e-05	3	105	2	CID006478913
Drug	azaquinone	HSP90AA1 HSP90AA2P	6.30e-05	3	105	2	CID000099132
Drug	d 1 v	HSP90AA1 HSP90AA2P	6.30e-05	3	105	2	CID000683940
Drug	AC1MD0RC	HSP90AA1 HSP90AA2P	6.30e-05	3	105	2	CID002829073
Drug	HM-9	HSP90AA1 HSP90AA2P	6.30e-05	3	105	2	CID000433437
Drug	Glyoxylspermidine	HSP90AA1 HSP90AA2P	6.30e-05	3	105	2	CID000133564
Drug	gamma-Glutamylglutamate	MPL HSP90AA1 HSP90AA2P	1.03e-04	20	105	3	CID000092865
Drug	dimethyl pimelimidate	HSP90AA1 HSP90AA2P HSP90AB1	1.03e-04	20	105	3	CID000065403
Drug	N-(5-methylisoxazol-3-yl)-2-(4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetamide	HSP90AA1 HSP90AB1	1.26e-04	4	105	2	ctd:C576667
Drug	uranyl chloride	HSP90AA1 HSP90AA2P	1.26e-04	4	105	2	CID000082259
Drug	methoxyhydroquinone	HSP90AA1 HSP90AA2P	1.26e-04	4	105	2	CID000069988
Drug	Poly C	GRIA1 GRIN2A	1.26e-04	4	105	2	ctd:D011066
Drug	11p110	HSP90AA1 HSP90AA2P	1.26e-04	4	105	2	CID002382787
Drug	tamoxifen aziridine	HSP90AA1 HSP90AA2P HSP90AB1	1.38e-04	22	105	3	CID003033894
Drug	CCT018159	HSP90AA1 HSP90AA2P HSP90AB1	1.38e-04	22	105	3	CID005327091
Drug	Ra X Peptide	EFEMP2 EIF2AK2 HSP90AA1 HSP90AA2P	1.50e-04	58	105	4	CID006444175
Drug	S2A	HSP90AA1 HSP90AA2P HSP90AB1	1.58e-04	23	105	3	CID016058643
Drug	oleth-3-phosphate	LCP2 PTGFRN CD37 ATP2B4	1.71e-04	60	105	4	CID000021452
Drug	fenthion	MCF2 HSP90AA1 HSP90AA2P	1.80e-04	24	105	3	CID000003346
Drug	HF-2035	CAMK1D CAMK1G MYLK2	2.04e-04	25	105	3	CID006439511
Drug	1uyd	HSP90AA1 HSP90AA2P	2.09e-04	5	105	2	CID000448970
Drug	HCV-796	HSP90AA1 HSP90AA2P	2.09e-04	5	105	2	CID011561383
Drug	chaetochromin	HSP90AA1 HSP90AA2P	2.09e-04	5	105	2	CID000053277
Drug	1,1-diphenyl-2-propyn-1-ol	HSP90AA1 HSP90AA2P	2.09e-04	5	105	2	CID000092976
Drug	1uy7	HSP90AA1 HSP90AA2P	2.09e-04	5	105	2	CID005289227
Drug	Org 31806	HSP90AA1 HSP90AA2P	2.09e-04	5	105	2	CID000164147
Drug	CRT0044876	HSP90AA1 HSP90AA2P	2.09e-04	5	105	2	CID000081409
Drug	CTK8G2960	PACSIN1 GRIN2A EIF2AK2 HSP90AA1 HSP90AA2P HSP90AB1	2.26e-04	186	105	6	CID005361912
Disease	blood copper measurement	CAMK1D MAPKAPK5 ADPRS ATP2B4	2.85e-05	50	103	4	EFO_0007578
Disease	Morphine Abuse	GRIA1 GRIN2A	2.51e-04	7	103	2	C0600272
Disease	Morphine Dependence	GRIA1 GRIN2A	2.51e-04	7	103	2	C0026552
Disease	primary immunodeficiency disease (is_implicated_in)	LCP2 POLR3F DPP9	4.30e-04	42	103	3	DOID:612 (is_implicated_in)
Disease	carbohydrate measurement	GRIA1 PTPRM ATP2B4	5.62e-04	46	103	3	EFO_0004998
Disease	hyperhomocysteinemia (implicated_via_orthology)	GRIA1 GRIN2A	6.50e-04	11	103	2	DOID:9279 (implicated_via_orthology)
Disease	cesarean section, intelligence	GRIN2A MYLK2	7.78e-04	12	103	2	EFO_0004337, EFO_0009636
Disease	idiopathic pulmonary fibrosis	TTYH1 DPP9 AKAP13	1.05e-03	57	103	3	EFO_0000768
Disease	central nervous system disease (implicated_via_orthology)	SMARCA5 GRIA1	1.40e-03	16	103	2	DOID:331 (implicated_via_orthology)
Disease	grip strength measurement	ATXN2L PAK5 GRIA1 OLA1 ZC3H4 HAS1	1.45e-03	350	103	6	EFO_0006941
Disease	sexual dimorphism measurement	ATXN2L FNDC3B CACNA2D2 PACSIN1 RIOK3 GRIN2A ADAMTSL3 ZC3H4 SF3A3 ANKRD11 MAP3K11	1.68e-03	1106	103	11	EFO_0021796
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	ATXN2L FNDC3B RELN ADAMTSL3 ZC3H4 ATP2B4	1.77e-03	364	103	6	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	intrahepatic cholangiocarcinoma (is_marker_for)	HSP90AA1 HSP90AB1	1.99e-03	19	103	2	DOID:4928 (is_marker_for)
Disease	corneal hysteresis	FNDC3B ANAPC1	2.20e-03	20	103	2	EFO_0010066
Disease	Huntington's disease (is_implicated_in)	GRIN2A EIF2AK2	2.91e-03	23	103	2	DOID:12858 (is_implicated_in)
Disease	frailty measurement	INO80 MAPK6	2.91e-03	23	103	2	EFO_0009885
Disease	Periodontal Pocket	ISM1 TENM3	3.44e-03	25	103	2	EFO_1001393
Disease	Ataxia	CACNA2D2 ADPRS	3.44e-03	25	103	2	C0004134

Protein segments in the cluster

Peptide	Gene	Start	Entry
AWALFPPSDDYDDTD	TTYH1	416	Q9H313
NPFGEDDDDFETNWC	BEST3	296	Q8N1M1
VGTEESDFEGWAFPF	ALKBH4	56	Q9NXW9
ASPDEVDDTYLQEFW	AMER2	426	Q8N7J2
DEGYWDSTTPGPEED	AMER2	521	Q8N7J2
EYGWSSSEFESYEEQ	ARHGEF10	271	O15013
YDPEDTWQDEEYFGS	PRMT2	91	P55345
DFKGEDSWDSPVTDY	ANKRD11	851	Q6UB99
EDWTENPEPFNASFY	CACNA2D2	776	Q9NY47
APSRGEDDGESFYTW	ERO1B	221	Q86YB8
EENAGEPDSWSSLSY	AKAP13	221	Q12802
SDSDVDYDFLNDWGP	CDH5	751	P33151
AYRDFDDTEPSWDNE	ATP2B4	641	P23634
WEGGDSNSDDYDLES	ATXN2L	231	Q8WWM7
DYGSPSQFWEQELES	CCDC69	166	A6NI79
EEPDSAAKSGEAWYE	PRODH2	191	Q9UF12
AFDDDSTSWAYQEGI	RFTN2	251	Q52LD8
EYFFTAGPDEVRAWT	OLA1	306	Q9NTK5
TAADTVIFYDSDWNP	INO80	1186	Q9ULG1
ARPSETGSDDDWEYL	ANAPC1	696	Q9H1A4
CEPQWFYEETESSDD	C8orf76	36	Q96K31
AYSESEWGPSLDDYD	PAK5	251	Q9P286
FWGSNTATTEYEAPA	DGKK	946	Q5KSL6
DDEQYAWESSAGGSF	HSP90AB1	151	P08238
GSFEFPEEEWSQISE	MAPKAPK5	261	Q8IW41
GFDITYESNEWDTEP	MAN2A1	151	Q16706
EYLSNWFGERDFTPE	GEMIN2	196	O14893
WDEQGAHPSEDNDFY	LRRC25	256	Q8N386
STYDRDNDGWLTSDP	FGB	406	P02675
EDPAFDTNYSTEPCW	MAPK6	411	Q16659
SGNWYFDEETFEAVS	MYLK2	496	Q9H1R3
EIDYDGSGSVSQAEW	DGKA	166	P23743
DTLDNGDYGEPDYDW	KCT2	141	Q8NC54
PDYDWTTGPRDDDES	KCT2	151	Q8NC54
QYDADAEETGLDGSW	KIF24	1171	Q5T7B8
GEDFYRSTTPSEDIW	MYCLP1	16	P12525
DDEDSYPQGGWDTVF	GPR152	21	Q8TDT2
SGEDFAEWCEFTPYE	PLA2G4F	506	Q68DD2
EVPQESWDEGYSTLS	NBPF1	826	Q3BBV0
IPSKYDWSGAEESDD	KDM5A	1591	P29375
QPVFSGEDYDQWAVD	RELN	1201	P78509
YEFESPFWDDISESA	CAMK1G	236	Q96NX5
APEETTDSFWEVGNY	PACSIN1	11	Q9BY11
DRGQPYATEWSDDES	PACSIN1	351	Q9BY11
YATEWSDDESGNPFG	PACSIN1	356	Q9BY11
AYWAQAEDTAAPAEE	CBY2	266	Q8NA61
TWLVGTDAPEDTQYF	IL5RA	156	Q01344
DYASESPADEEEQWS	BLNK	51	Q8WV28
EEQWSDDFDSDYENP	BLNK	61	Q8WV28
CWDGFDYDPETSDDS	EIF2AK2	326	P19525
YDWSEPFSPGEDEFK	DPP9	466	Q86TI2
LTWEAVPGSEFSYAE	FCGBP	381	Q9Y6R7
GWESPDSSGADISEY	FNDC3B	786	Q53EP0
PESWQQSCEGYEETD	ADPRS	336	Q9NX46
GGWETFLSYEDPDQD	ELP3	431	Q9H9T3
VFADEDPATYVWDGN	HAS1	151	Q92839
LPSFEIGAWTEDDVY	MAP3K20	331	Q9NYL2
AEISEEPAEWSSNYF	MCF2	886	P10911
GFYPSDIAVEWESSG	IGHG3	301	P01860
DDEQYAWESSAGGSF	HSP90AA1	156	P07900
SPYEWHSEEFEEGRD	GRIA1	561	P42261
DEQSDWFYEKESGGA	GPATCH2	281	Q9NW75
EEPDSYTECTDGYEW	EFEMP2	31	O95967
YTECTDGYEWDPDSQ	EFEMP2	36	O95967
AESSPGEYEWEYDEE	SART3	76	Q15020
QPEYDSTDGEGDWSL	ISM1	211	B1AKI9
AQFPSDEEYGFWSSD	IPO13	401	O94829
AWIFNEYPSFVEEDS	CNTN3	156	Q9P232
DDEQYAWESSAGGSF	HSP90AA2P	156	Q14568
WTALFDYEPSGQDEL	MAP3K11	46	Q16584
GTNPEETAAEESWDY	CD37	131	P11049
KEEYESFFEGQSAPW	PTPRM	901	P28827
NYQFGSPEWDDYSDT	PHKG1	246	Q16816
SDYDGPSEQNFDWSF	PTGFRN	46	Q9P2B2
SRDGDWPSSVEFYAS	PLEKHF1	256	Q96S99
WGNVPDANYTSDEEE	STK33	431	Q9BYT3
PAAEDEGDTAWNYSF	WRAP53	136	Q9BUR4
DFYNWPDESFDEMDS	MOB4	21	Q9Y3A3
EVPQESWDEGYSTLS	NBPF12	826	Q5TAG4
GRGDNWYSEDEDTDT	RIC8B	461	Q9NVN3
WDQDPEQSTGNYSED	NANOGNB	41	Q7Z5D8
VTGGAWYSDQDFESE	POLR3F	161	Q9H1D9
QGSLFWDDGESIDTY	SI	1721	P14410
FSTVPNYDNDDEAWS	PI4KB	446	Q9UBF8
SGESLAYWPDRSDTE	FAM83F	101	Q8NEG4
AEYEFDSPYWDDISD	CAMK1D	236	Q8IU85
NDSYTEEEPEWFSAG	EIF4ENIF1	211	Q9NRA8
ASPEKGAETWFDSYD	CLN5	216	O75503
PYEDSDSSEDEVDWQ	RIOK3	121	O14730
EGFSYATEGESQEDW	SLC7A14	706	Q8TBB6
YFFSAESPEEQEAWI	PLEKHA6	136	Q9Y2H5
GEDFYRSTAPSEDIW	MYCL	16	P12524
FGPYDETTCIDWTDD	PWP2	141	Q15269
SDETGWTTFFDYDSE	TENM3	1621	Q9P273
GEYRDYSNDWSPSDT	VIPAS39	146	Q9H9C1
EDYPGWSEDSFGARV	PKHD1L1	3266	Q86WI1
FWDEEEAAPSGTYQL	MPL	51	P40238
SVDENYEWDSEFPGD	IGSF9	1081	Q9P2J2
SNFETYPENDWDTAA	PRKX	331	P51817
ENEEGDTGNWYSSDE	ZC3H4	796	Q9UPT8
GSDTAVDAAFEPVYW	ZDHHC16	56	Q969W1
WDDETPGPSYSSSEQ	TOPORS	416	Q9NS56
GEEPWFSEEEFSNQS	ZNF510	101	Q9Y2H8
WQPDTEEEYEDSSGN	SF3A3	471	Q12874
GLSSTEDEGEDPWYQ	RS1	21	O15537
PDVFNSADDFDSWFD	SMARCA5	356	O60264
TDLPTGWEEAYTFEG	PLEKHA5	56	Q9HAU0
EEYGRFDPSSWESVA	TMEM260	571	Q9NX78
EEWRSLDPSQTDFYG	ZNF641	121	Q96N77
DSETTYDWEYAGFTP	ADAMTSL3	641	P82987
EDFEPSDSRVQYFWE	HECTD3	761	Q5T447
DNGGWSSFEEDDYES	LCP2	101	Q13094
EFPSGLISVSYDDWD	GRIN2A	271	Q12879