Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glucan 1,4-alpha-glucosidase activity	MGAM MGAM2	3.35e-05	2	116	2	GO:0004339
GeneOntologyCellularComponent	anchoring junction	MPP1 CLDN14 OCEL1 SORBS1 ERBIN PDLIM4 MAGI2 FAP MISP FNDC1 CD44 LRRC7 PEAK1 CTNND2 ATP1B1 ALKBH6 PLEKHA7	3.80e-05	976	119	17	GO:0070161
GeneOntologyCellularComponent	actin-based cell projection	MPP1 UBE2K MYO6 MYO1B MTM1 PTPRQ CD44 LRRC7	1.94e-04	278	119	8	GO:0098858
GeneOntologyCellularComponent	cell-cell junction	MPP1 CLDN14 OCEL1 SORBS1 PDLIM4 MAGI2 FNDC1 LRRC7 CTNND2 ATP1B1 PLEKHA7	5.63e-04	591	119	11	GO:0005911
GeneOntologyCellularComponent	apical part of cell	MGAM OCEL1 PLB1 MYO6 MYO1B TF FAP PTPRQ CD44 ATP1B1 ATP4B	5.70e-04	592	119	11	GO:0045177
GeneOntologyCellularComponent	filopodium	UBE2K MYO6 MYO1B MTM1 LRRC7	6.95e-04	123	119	5	GO:0030175
GeneOntologyCellularComponent	male pronucleus	STPG4 TET3	8.80e-04	8	119	2	GO:0001940
GeneOntologyCellularComponent	zonula adherens	SORBS1 PLEKHA7	8.80e-04	8	119	2	GO:0005915
GeneOntologyCellularComponent	clathrin-coated pit	MYO6 AAK1 TF CEMIP	1.13e-03	80	119	4	GO:0005905
GeneOntologyCellularComponent	mediator complex	MED29 MED12L MED23	1.21e-03	37	119	3	GO:0016592
GeneOntologyCellularComponent	female pronucleus	STPG4 TET3	1.40e-03	10	119	2	GO:0001939
GeneOntologyCellularComponent	basal part of cell	ERBIN TF LEPR FAP PTPRQ CD44 LRRC7 ATP1B1	1.46e-03	378	119	8	GO:0045178
Domain	TF_fork_head_CS_2	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	9.48e-06	46	116	5	IPR030456
Domain	TF_fork_head_CS_1	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.06e-05	47	116	5	IPR018122
Domain	FH	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.30e-05	49	116	5	SM00339
Domain	FORK_HEAD_1	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.30e-05	49	116	5	PS00657
Domain	FORK_HEAD_2	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.30e-05	49	116	5	PS00658
Domain	Fork_head_dom	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.30e-05	49	116	5	IPR001766
Domain	FORK_HEAD_3	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.30e-05	49	116	5	PS50039
Domain	Forkhead	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.30e-05	49	116	5	PF00250
Domain	WHTH_DNA-bd_dom	CUL9 FOXD4L6 LARP1B FOXD4L5 FARSA FOXD4L4 FOXD4L1 FOXD4L3 HFM1	2.03e-05	242	116	9	IPR011991
Domain	SAXO1/2	SAXO2 SAXO1	3.82e-05	2	116	2	IPR033336
Domain	MAGE	MAGEB1 MAGEB18 MAGED2 MAGEB17	5.67e-05	34	116	4	SM01373
Domain	-	CUL9 FOXD4L6 LARP1B FOXD4L5 FARSA FOXD4L4 FOXD4L1 FOXD4L3	6.54e-05	218	116	8	1.10.10.10
Domain	MAGE	MAGEB1 MAGEB18 MAGED2 MAGEB17	7.14e-05	36	116	4	PS50838
Domain	MHD_dom	MAGEB1 MAGEB18 MAGED2 MAGEB17	7.14e-05	36	116	4	IPR002190
Domain	MAGE	MAGEB1 MAGEB18 MAGED2 MAGEB17	7.14e-05	36	116	4	PF01454
Domain	Gal_mutarotase_N	MGAM MGAM2	2.28e-04	4	116	2	IPR031727
Domain	NtCtMGAM_N	MGAM MGAM2	2.28e-04	4	116	2	PF16863
Domain	ATPASE_NA_K_BETA_2	ATP1B1 ATP4B	2.28e-04	4	116	2	PS00391
Domain	MAGE_N	MAGEB1 MAGEB18 MAGEB17	2.46e-04	20	116	3	SM01392
Domain	PDZ	MPP1 ERBIN PDLIM4 MAGI2 LRRC7 RIMS2	2.50e-04	141	116	6	PF00595
Domain	PDZ	MPP1 ERBIN PDLIM4 MAGI2 LRRC7 RIMS2	3.24e-04	148	116	6	SM00228
Domain	MAGE_N	MAGEB1 MAGEB18 MAGEB17	3.30e-04	22	116	3	PF12440
Domain	MAGE_N	MAGEB1 MAGEB18 MAGEB17	3.30e-04	22	116	3	IPR021072
Domain	EGF_Ca-bd_CS	EDIL3 LRP1B EGFL6 BMP1 C1S	3.47e-04	97	116	5	IPR018097
Domain	-	MPP1 ERBIN PDLIM4 MAGI2 LRRC7 RIMS2	3.49e-04	150	116	6	2.30.42.10
Domain	PDZ	MPP1 ERBIN PDLIM4 MAGI2 LRRC7 RIMS2	3.61e-04	151	116	6	PS50106
Domain	PDZ	MPP1 ERBIN PDLIM4 MAGI2 LRRC7 RIMS2	3.74e-04	152	116	6	IPR001478
Domain	Na/K_ATPase_sub_beta	ATP1B1 ATP4B	3.78e-04	5	116	2	IPR000402
Domain	Na_K-ATPase	ATP1B1 ATP4B	3.78e-04	5	116	2	PF00287
Domain	ATPASE_NA_K_BETA_1	ATP1B1 ATP4B	3.78e-04	5	116	2	PS00390
Domain	EGF_CA	EDIL3 LRP1B EGFL6 BMP1 C1S	3.81e-04	99	116	5	PS01187
Domain	ASX_HYDROXYL	EDIL3 LRP1B EGFL6 BMP1 C1S	3.99e-04	100	116	5	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	EDIL3 LRP1B EGFL6 BMP1 C1S	5.21e-04	106	116	5	IPR000152
Domain	Peptidase_S8_Asp-AS	FURIN PCSK4	5.64e-04	6	116	2	IPR023827
Domain	Glyco_hydro_31_AS	MGAM MGAM2	5.64e-04	6	116	2	IPR030458
Domain	Peptidase_Metallo	MMP27 BMP1 MMP3	7.58e-04	29	116	3	IPR006026
Domain	ZnMc	MMP27 BMP1 MMP3	7.58e-04	29	116	3	SM00235
Domain	STAT_TF_DNA-bd_sub	STAT1 STAT4	7.87e-04	7	116	2	IPR012345
Domain	STAT	STAT1 STAT4	7.87e-04	7	116	2	IPR001217
Domain	Glyco_hydro_31	MGAM MGAM2	7.87e-04	7	116	2	IPR000322
Domain	STAT_int	STAT1 STAT4	7.87e-04	7	116	2	SM00964
Domain	STAT_TF_DNA-bd	STAT1 STAT4	7.87e-04	7	116	2	IPR013801
Domain	STAT_bind	STAT1 STAT4	7.87e-04	7	116	2	PF02864
Domain	STAT_int	STAT1 STAT4	7.87e-04	7	116	2	PF02865
Domain	Glyco_hydro_31	MGAM MGAM2	7.87e-04	7	116	2	PF01055
Domain	-	STAT1 STAT4	7.87e-04	7	116	2	1.10.532.10
Domain	P_proprotein	FURIN PCSK4	7.87e-04	7	116	2	PF01483
Domain	STAT_alpha	STAT1 STAT4	7.87e-04	7	116	2	PF01017
Domain	S8_pro-domain	FURIN PCSK4	7.87e-04	7	116	2	IPR032815
Domain	-	STAT1 STAT4	7.87e-04	7	116	2	1.20.1050.20
Domain	STAT_TF_prot_interaction	STAT1 STAT4	7.87e-04	7	116	2	IPR013799
Domain	STAT_TF_coiled-coil	STAT1 STAT4	7.87e-04	7	116	2	IPR015988
Domain	PrprotnconvertsP	FURIN PCSK4	7.87e-04	7	116	2	IPR002884
Domain	-	STAT1 STAT4	7.87e-04	7	116	2	2.60.40.630
Domain	-	FURIN PCSK4	7.87e-04	7	116	2	3.30.70.850
Domain	S8_pro-domain	FURIN PCSK4	7.87e-04	7	116	2	PF16470
Domain	GLYCOSYL_HYDROL_F31_1	MGAM MGAM2	7.87e-04	7	116	2	PS00129
Domain	EGF_CA	EDIL3 LRP1B EGFL6 BMP1 C1S	9.86e-04	122	116	5	SM00179
Domain	STAT_TF_alpha	STAT1 STAT4	1.04e-03	8	116	2	IPR013800
Domain	Trefoil	MGAM MGAM2	1.04e-03	8	116	2	PF00088
Domain	Tim17/Tim22/Tim23/PMP24	TIMM23 TIMMDC1	1.04e-03	8	116	2	IPR003397
Domain	Tim17	TIMM23 TIMMDC1	1.04e-03	8	116	2	PF02466
Domain	EGF-like_Ca-bd_dom	EDIL3 LRP1B EGFL6 BMP1 C1S	1.06e-03	124	116	5	IPR001881
Domain	-	CUL9 EDIL3 FURIN PCSK4	1.11e-03	73	116	4	2.60.120.260
Domain	Peptidase_S8_His-AS	FURIN PCSK4	1.34e-03	9	116	2	IPR022398
Domain	Peptidase_S8_Ser-AS	FURIN PCSK4	1.34e-03	9	116	2	IPR023828
Domain	P_TREFOIL_2	MGAM MGAM2	1.34e-03	9	116	2	PS51448
Domain	PD	MGAM MGAM2	1.34e-03	9	116	2	SM00018
Domain	Peptidase_S8_subtilisin-rel	FURIN PCSK4	1.67e-03	10	116	2	IPR015500
Domain	SUBTILASE_ASP	FURIN PCSK4	1.67e-03	10	116	2	PS00136
Domain	SUBTILASE_HIS	FURIN PCSK4	1.67e-03	10	116	2	PS00137
Domain	SUBTILASE_SER	FURIN PCSK4	1.67e-03	10	116	2	PS00138
Domain	EGF_CA	LRP1B EGFL6 BMP1 C1S	2.03e-03	86	116	4	PF07645
Domain	-	MGAM MGAM2	2.03e-03	11	116	2	4.10.110.10
Domain	-	FURIN PCSK4	2.03e-03	11	116	2	3.40.50.200
Domain	Peptidase_S8/S53_dom	FURIN PCSK4	2.03e-03	11	116	2	IPR000209
Domain	Peptidase_S8	FURIN PCSK4	2.03e-03	11	116	2	PF00082
Domain	P_trefoil_dom	MGAM MGAM2	2.42e-03	12	116	2	IPR000519
Domain	Pkinase	NPR2 AAK1 TSSK2 NEK7 SGK3 PIK3R4 PEAK1 TSSK1B	2.61e-03	381	116	8	PF00069
Domain	Galactose-bd-like	CUL9 EDIL3 FURIN PCSK4	2.80e-03	94	116	4	IPR008979
Domain	Growth_fac_rcpt_	LRP1B EGFL6 BMP1 FURIN PCSK4	2.91e-03	156	116	5	IPR009030
Domain	Prot_kinase_dom	NPR2 AAK1 TSSK2 NEK7 SGK3 PIK3R4 FGFR2 PEAK1 TSSK1B	3.45e-03	489	116	9	IPR000719
Domain	PROTEIN_KINASE_DOM	NPR2 AAK1 TSSK2 NEK7 SGK3 PIK3R4 FGFR2 PEAK1 TSSK1B	3.64e-03	493	116	9	PS50011
Domain	Pept_M10A_Zn_BS	MMP27 MMP3	3.81e-03	15	116	2	IPR021158
Domain	Guanylate_kinase_CS	MPP1 MAGI2	4.34e-03	16	116	2	IPR020590
Domain	Gal_mutarotase_SF_dom	MGAM MGAM2	4.89e-03	17	116	2	IPR011013
Domain	Hemopexin_CS	MMP27 MMP3	4.89e-03	17	116	2	IPR018486
Domain	Propept_inh	FURIN PCSK4	4.89e-03	17	116	2	IPR009020
Domain	Pept_M10A_stromelysin-type	MMP27 MMP3	5.48e-03	18	116	2	IPR016293
Domain	Furin_repeat	FURIN PCSK4	5.48e-03	18	116	2	IPR006212
Domain	FU	FURIN PCSK4	5.48e-03	18	116	2	SM00261
Pubmed	Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	2.58e-12	6	119	5	27092474
Pubmed	The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	2.39e-11	8	119	5	8530406
Pubmed	An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	5.37e-11	9	119	5	12412011
Pubmed	A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	5.42e-10	13	119	5	16884697
Pubmed	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	5.42e-10	13	119	5	7957066
Pubmed	Six members of the mouse forkhead gene family are developmentally regulated.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.26e-09	15	119	5	7689224
Pubmed	Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.26e-09	15	119	5	22045912
Pubmed	Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.83e-09	16	119	5	8861101
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.83e-09	16	119	5	10208738
Pubmed	Functional equivalency between Otx2 and Otx1 in development of the rostral head.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	4.82e-09	19	119	5	9895322
Pubmed	Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	6.41e-09	20	119	5	12812790
Pubmed	Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	8.39e-09	21	119	5	9449667
Pubmed	Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.08e-08	22	119	5	17389379
Pubmed	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	ACADL CYP4B1 SORBS1 PPARG LEPR STAT1 EHHADH LSS IRS2 MED23	1.65e-08	250	119	10	18660489
Pubmed	Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.74e-08	24	119	5	11820816
Pubmed	A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	1.74e-08	24	119	5	29992973
Pubmed	Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	2.68e-08	26	119	5	15857913
Pubmed	Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	4.79e-08	29	119	5	22972626
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RALGAPA1 ACADL NRDC MYO6 AAK1 SPIRE1 SORBS1 ERBIN TF OPCML PIK3R4 AGBL4 MAGI2 MISP FARSA LRRC7 PEAK1 CTNND2 ATP1B1 PLEKHA7	8.55e-08	1431	119	20	37142655
Pubmed	Hemicentin 1 influences podocyte dynamic changes in glomerular diseases.	PPARG EDIL3 LEPR	1.56e-07	4	119	3	29488390
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FNIP2 EIF4H CUL9 SORBS1 ERBIN MAGI2 SETDB1 RRP12 CHPF2 LRRC7 TET3	1.68e-07	407	119	11	12693553
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	CUL9 SORBS1 CEMIP MAGI2 SETDB1 RRP12 MED23	3.43e-07	130	119	7	12421765
Pubmed	FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.	FOXD4L6 FOXD4L5 FOXD4L4	3.89e-07	5	119	3	12234674
Pubmed	Combination of DPP-4 inhibitor and PPARγ agonist exerts protective effects on pancreatic β-cells in diabetic db/db mice through the augmentation of IRS-2 expression.	PPARG LEPR IRS2	3.89e-07	5	119	3	26116826
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 COBLL1 AAK1 TSSK2 SPIRE1 SORBS1 LARP1B ERBIN DNAH7 PIK3R4 IRS2 PEAK1 PLEKHA7 TSSK1B	1.56e-06	861	119	14	36931259
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MYO6 VPS39 CUL9 SORBS1 EDIL3 LRP1B TF STAT1 PIK3R4 MAGI2 SETDB1 SCG2 MTM1 C1S CTNND2 ALKBH6 MGAT5B	1.87e-06	1285	119	17	35914814
Pubmed	Genome-scale study of transcription factor expression in the branching mouse lung.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	3.51e-06	67	119	5	22711520
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	EIF4H MYO6 COBLL1 AAK1 MYO1B SORBS1 ERBIN STAT1 LRRC7 PEAK1 PLEKHA7	4.09e-06	565	119	11	25468996
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	RALGAPA1 MYO6 COBLL1 AAK1 MYO1B ERBIN STAT1 FARSA MAGED2 LRRC7 IRS2 PEAK1	6.02e-06	708	119	12	39231216
Pubmed	Host PDZ-containing proteins targeted by SARS-CoV-2.	ERBIN MAGI2 LRRC7 RIMS2	6.28e-06	35	119	4	33864728
Pubmed	Loci controlling plasma non-HDL and HDL cholesterol levels in a C57BL /6J x CASA /Rk intercross.	PPARG LEPR IRS2	6.32e-06	11	119	3	12810823
Pubmed	Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors.	ERBIN LRRC7 CTNND2	6.32e-06	11	119	3	39256359
Pubmed	Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions.	FOXD4L4 FOXD4L1 FOXD4L3	6.32e-06	11	119	3	12421752
Pubmed	Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.	FOXD4L6 FOXD4L5 PDLIM4 FOXD4L4 FOXD4L1 MRPL15 FOXD4L3 FGFR2	1.10e-05	306	119	8	18973680
Pubmed	Fanconi anemia core complex gene promoters harbor conserved transcription regulatory elements.	STAT1 STAT4	1.16e-05	2	119	2	21826217
Pubmed	High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.	STAT1 STAT4	1.16e-05	2	119	2	19333953
Pubmed	Polymorphisms of signal transducers and activators of transcription 1 and 4 (STAT1 and STAT4) contribute to progression of childhood IgA nephropathy.	STAT1 STAT4	1.16e-05	2	119	2	20045654
Pubmed	STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.	STAT1 STAT4	1.16e-05	2	119	2	24920804
Pubmed	cDNA cloning, expression and chromosome mapping of the human STAT4 gene: both STAT4 and STAT1 genes are mapped to 2q32.2-->q32.3.	STAT1 STAT4	1.16e-05	2	119	2	9284918
Pubmed	PPARγ Controls Ectopic Adipogenesis and Cross-Talks with Myogenesis During Skeletal Muscle Regeneration.	PPARG EDIL3	1.16e-05	2	119	2	30011852
Pubmed	Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region.	STAT1 STAT4	1.16e-05	2	119	2	18803832
Pubmed	Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.	STAT1 STAT4	1.16e-05	2	119	2	9630226
Pubmed	Interaction of S-SCAM with neural plakophilin-related Armadillo-repeat protein/delta-catenin.	MAGI2 CTNND2	1.16e-05	2	119	2	10080919
Pubmed	Epigenetic control of innate and adaptive immune memory.	STAT1 STAT4	1.16e-05	2	119	2	30082830
Pubmed	Signal transducer and activator of transcription 1 and matrix metalloproteinase 3 genetic expression and clinical significance on urothelial tumors after renal transplantation.	STAT1 MMP3	1.16e-05	2	119	2	20832538
Pubmed	L312, a novel PPARγ ligand with potent anti-diabetic activity by selective regulation.	PPARG LEPR	1.16e-05	2	119	2	25305559
Pubmed	Tyrosine phosphorylation regulates the partitioning of STAT1 between different dimer conformations.	STAT1 STAT4	1.16e-05	2	119	2	18591661
Pubmed	Control of beta cell function and proliferation in mice stimulated by small-molecule glucokinase activator under various conditions.	LEPR IRS2	1.16e-05	2	119	2	22456697
Pubmed	The Ets transcription factor ERM is Th1-specific and induced by IL-12 through a Stat4-dependent pathway.	STAT1 STAT4	1.16e-05	2	119	2	10097133
Pubmed	CD44 promotes angiogenesis in myocardial infarction through regulating plasma exosome uptake and further enhancing FGFR2 signaling transduction.	CD44 FGFR2	1.16e-05	2	119	2	36463112
Pubmed	Identification of Diagnostic Variants in FGFR2 and NPR2 Genes in a Chinese Family Affected by Crouzon Syndrome and Acromesomelic Dysplasia, Type Maroteaux.	NPR2 FGFR2	1.16e-05	2	119	2	36322898
Pubmed	Deletion of CD44 promotes adipogenesis by regulating PPARγ and cell cycle-related pathways.	PPARG CD44	1.16e-05	2	119	2	38692289
Pubmed	Disease Risk-Associated Genetic Variants in STAT1 and STAT4 Function in a Complementary Manner to Increase Pattern-Recognition Receptor-Induced Outcomes in Human Macrophages.	STAT1 STAT4	1.16e-05	2	119	2	32661180
Pubmed	Dynamic compartmentalization of protein tyrosine phosphatase receptor Q at the proximal end of stereocilia: implication of myosin VI-based transport.	MYO6 PTPRQ	1.16e-05	2	119	2	18412156
Pubmed	Localization of Kex2-like processing endoproteases, furin and PC4, within mouse testis by in situ hybridization.	FURIN PCSK4	1.16e-05	2	119	2	8422932
Pubmed	Regulating type 1 IFN effects in CD8 T cells during viral infections: changing STAT4 and STAT1 expression for function.	STAT1 STAT4	1.16e-05	2	119	2	22968462
Pubmed	Complement Activation and STAT4 Expression Are Associated with Early Inflammation in Diabetic Wounds.	LEPR STAT4	1.16e-05	2	119	2	28107529
Pubmed	Human FAM154A (SAXO1) is a microtubule-stabilizing protein specific to cilia and related structures.	SAXO2 SAXO1	1.16e-05	2	119	2	25673876
Pubmed	Nephropathy in Pparg-null mice highlights PPARγ systemic activities in metabolism and in the immune system.	PPARG EDIL3	1.16e-05	2	119	2	28182703
Pubmed	An overview of the MAGE gene family with the identification of all human members of the family.	MAGEB1 MAGED2 MAGEB17	3.07e-05	18	119	3	11454705
Pubmed	Association of FAM65B, AGBL4, and CUX2 genetic polymorphisms with susceptibility to antituberculosis drug-induced hepatotoxicity: validation study in a Chinese Han population.	CUX2 AGBL4	3.47e-05	3	119	2	30720667
Pubmed	IL-21 promotes differentiation of naive CD8 T cells to a unique effector phenotype.	STAT1 STAT4	3.47e-05	3	119	2	17548600
Pubmed	Evolution of testis-specific kinases TSSK1B and TSSK2 in primates.	TSSK2 TSSK1B	3.47e-05	3	119	2	23258646
Pubmed	Skeletal stem cell fate defects caused by Pdgfrb activating mutation.	EDIL3 STAT1	3.47e-05	3	119	2	34738614
Pubmed	A C-terminal lobe of the beta subunit of Na,K-ATPase and H,K-ATPase resembles cell adhesion molecules.	ATP1B1 ATP4B	3.47e-05	3	119	2	19694409
Pubmed	STAT1 and STAT6 Act as Antagonistic Regulators of PPARγ in Diabetic Patients with and without Cardiovascular Diseases.	PPARG STAT1	3.47e-05	3	119	2	29739101
Pubmed	The role of Tyk2, Stat1 and Stat4 in LPS-induced endotoxin signals.	STAT1 STAT4	3.47e-05	3	119	2	15226272
Pubmed	SIRT6 transcriptionally regulates fatty acid transport by suppressing PPARγ.	PPARG LEPR	3.47e-05	3	119	2	34077730
Pubmed	NRD1, which encodes nardilysin protein, promotes esophageal cancer cell invasion through induction of MMP2 and MMP3 expression.	NRDC MMP3	3.47e-05	3	119	2	24168165
Pubmed	Epineurial adipocytes are dispensable for Schwann cell myelination.	PPARG EDIL3	3.47e-05	3	119	2	22849425
Pubmed	Circ_FURIN knockdown assuages Testosterone-induced human ovarian granulosa-like tumor cell disorders by sponging miR-423-5p to reduce MTM1 expression in polycystic ovary syndrome.	FURIN MTM1	3.47e-05	3	119	2	35177076
Pubmed	K153R polymorphism in myostatin gene increases the rate of promyostatin activation by furin.	BMP1 FURIN	3.47e-05	3	119	2	25543063
Pubmed	A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.	LEPR IRS2	3.47e-05	3	119	2	24037094
Pubmed	Genetics of leptin and obesity: a HuGE review.	PPARG LEPR	3.47e-05	3	119	2	15972940
Pubmed	Erythrocyte and leukocyte dynamics in the retinal capillaries of diabetic mice.	LEPR STAT1	3.47e-05	3	119	2	12957148
Pubmed	Dermal distribution of hyaluronan in psoriatic arthritis; coexistence of CD44, MMP3 and MMP9.	CD44 MMP3	3.47e-05	3	119	2	22278305
Pubmed	Leptin gene (TTTC)(n) microsatellite polymorphism as well as leptin receptor R223Q and PPARgamma2 P12A substitutions are not associated with hypertensive disorders in pregnancy.	PPARG LEPR	3.47e-05	3	119	2	20070288
Pubmed	CYP2J2 attenuates metabolic dysfunction in diabetic mice by reducing hepatic inflammation via the PPARγ.	PPARG LEPR	3.47e-05	3	119	2	25389363
Pubmed	Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis.	LEPR IRS2	3.47e-05	3	119	2	24567904
Pubmed	Carbon monoxide (CO)-releasing molecule-derived CO regulates tissue factor and plasminogen activator inhibitor type 1 in human endothelial cells.	PPARG TF	3.47e-05	3	119	2	22819264
Pubmed	Multilocus analyses of seven candidate genes suggest interacting pathways for obesity-related traits in Brazilian populations.	PPARG LEPR	3.47e-05	3	119	2	21233811
Pubmed	Idebenone and coenzyme Q10 are novel PPARα/γ ligands, with potential for treatment of fatty liver diseases.	PPARG LEPR	3.47e-05	3	119	2	30171034
Pubmed	[Cloning and expression of Tssk1 & Tssk2 in mice and the presence & localization of them in mature sperm].	TSSK2 TSSK1B	3.47e-05	3	119	2	22855445
Pubmed	Sustained Post-Developmental T-Bet Expression Is Critical for the Maintenance of Type One Innate Lymphoid Cells In Vivo.	STAT1 STAT4	3.47e-05	3	119	2	34795671
Pubmed	PPARgamma in placental angiogenesis.	PPARG EDIL3	3.47e-05	3	119	2	20810566
Pubmed	Stat3 and Stat4: members of the family of signal transducers and activators of transcription.	STAT1 STAT4	3.47e-05	3	119	2	7545930
Pubmed	Immunohistochemical analysis of the expression of two serine-threonine kinases in the maturing mouse testis.	TSSK2 TSSK1B	3.47e-05	3	119	2	9651519
Pubmed	Distinct characteristics of murine STAT4 activation in response to IL-12 and IFN-alpha.	STAT1 STAT4	3.47e-05	3	119	2	17015705
Pubmed	Therapeutic potential of peroxisome proliferators--activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes.	PPARG LEPR	3.47e-05	3	119	2	18065517
Pubmed	Polymorphisms in adiposity-related genes are associated with age at menarche and menopause in breast cancer patients and healthy women.	PPARG LEPR	3.47e-05	3	119	2	22537818
Pubmed	Expression of hepatic fat-specific protein 27 depends on the specific etiology of fatty liver.	PPARG LEPR	3.47e-05	3	119	2	24189421
Pubmed	A reciprocal regulatory circuit between CD44 and FGFR2 via c-myc controls gastric cancer cell growth.	CD44 FGFR2	3.47e-05	3	119	2	27107424
Pubmed	Targeting Peroxisome Proliferator-Activated Receptor-Gamma Decreases Host Mortality After Influenza Infection in Obese Mice.	PPARG LEPR	3.47e-05	3	119	2	31009317
Pubmed	Polymorphisms in LEPR, PPARG and APM1 genes: associations with energy intake and metabolic traits in young children.	PPARG LEPR	3.47e-05	3	119	2	24343628
Pubmed	FAM3A is a target gene of peroxisome proliferator-activated receptor gamma.	PPARG LEPR	3.47e-05	3	119	2	23562554
Pubmed	Densin-180 interacts with delta-catenin/neural plakophilin-related armadillo repeat protein at synapses.	LRRC7 CTNND2	3.47e-05	3	119	2	11729199
Pubmed	Sex Hormone-Binding Globulin Reduction in Metabolic Disorders May Play a Role in NAFLD Development.	PPARG LEPR	3.47e-05	3	119	2	28359088
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	FOXD4L6 PPARG STAT1 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3	3.56e-05	263	119	7	20932939
Pubmed	Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection.	EDIL3 STAT1 STAT4	3.64e-05	19	119	3	32075740
Pubmed	An Alternative Splicing Program for Mouse Craniofacial Development.	MYO1B SORBS1 CD44	4.97e-05	21	119	3	33013468
Cytoband	9q21.11	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.12e-06	30	119	4	9q21.11
Cytoband	Xp21.3	MAGEB1 MAGEB18 PPP4R3C	5.91e-05	29	119	3	Xp21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr2q32	MYO1B DNAH7 STAT1 STAT4	2.00e-04	110	119	4	chr2q32
Cytoband	Ensembl 112 genes in cytogenetic band chrXp21	MAGEB1 MAGEB18 PPP4R3C	1.39e-03	84	119	3	chrXp21
GeneFamily	MAGE family	MAGEB1 MAGEB18 MAGED2 MAGEB17	2.35e-05	40	76	4	1136
GeneFamily	PDZ domain containing	MPP1 ERBIN PDLIM4 MAGI2 LRRC7 RIMS2	4.31e-05	152	76	6	1220
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	FNIP2 NPR2 DENND2D	1.54e-04	25	76	3	504
GeneFamily	Cyclins\|Mediator complex	MED29 MED12L MED23	3.56e-04	33	76	3	1061
GeneFamily	Proprotein convertase subtilisin/kexin family	FURIN PCSK4	6.16e-04	9	76	2	973
GeneFamily	Endogenous ligands\|Matrix metallopeptidases	MMP27 MMP3	4.53e-03	24	76	2	891
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	MPP1 MAGI2	5.31e-03	26	76	2	904
Coexpression	LAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE	RALGAPA1 COBLL1 AAK1 SPIRE1 MYO1B LRP1B AGBL4 SPIDR ATP1B1	9.07e-08	171	119	9	M39234
Coexpression	GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN	UBE2K LAPTM4B OPCML MISP FURIN RRP12 CD44 ATP1B1	3.66e-06	199	119	8	M8388
Coexpression	GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP	NPR2 PLAAT1 FYTTD1 CYP4B1 AAK1 PPARG TF LEPR	3.80e-06	200	119	8	M7765
Coexpression	GOZGIT_ESR1_TARGETS_DN	FNIP2 KRT13 MYO6 COBLL1 MYO1B LEPR STAT1 SGK3 CEMIP CD44 FGFR2 CTNND2 ATP1B1 PLEKHA7	1.37e-05	786	119	14	M10961
Coexpression	GSE21927_SPLEEN_VS_C26GM_TUMOR_MONOCYTE_BALBC_DN	RALGAPA1 GALNT3 LAPTM4B AAK1 LARP1B FAP MGAT5B	3.04e-05	194	119	7	M7573
Coexpression	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	EDIL3 PDLIM4 BMP1 FAP SCG2 CD44 MMP3	3.69e-05	200	119	7	M5930
Coexpression	GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN	MPP1 GALNT3 COBLL1 FAP FNDC1 CD44 MED12L	3.69e-05	200	119	7	M5616
Coexpression	LAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2	EDIL3 AGBL4 MAGI2 SPIDR PLEKHA7	4.60e-05	86	119	5	M39248
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 COBLL1 DNAH7 AGBL4 CD44 ATP1B1 RIMS2 PLEKHA7 HYDIN	3.14e-09	197	119	9	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLB1 SAXO1 LRP1B FREM1 PTPRQ C1S TDRD6 HYDIN	1.20e-08	160	119	8	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLB1 SAXO1 LRP1B FREM1 PTPRQ C1S TDRD6 HYDIN	1.20e-08	160	119	8	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 COBLL1 LRP1B DNAH7 AGBL4 FGFR2 ATP1B1 PLEKHA7	5.61e-08	195	119	8	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 COBLL1 DNAH7 AGBL4 FGFR2 ATP1B1 PLEKHA7 HYDIN	5.83e-08	196	119	8	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CLDN14 MYO6 COBLL1 SPIRE1 LRP1B SCG2 RIMS2	6.04e-07	182	119	7	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 SPIRE1 MYO1B FREM1 STAT1 AGBL4 ATP1B1	6.26e-07	183	119	7	d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 SPIRE1 MYO1B LRP1B FREM1 AGBL4 ATP1B1	6.99e-07	186	119	7	d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 SPIRE1 MYO1B LRP1B FREM1 AGBL4 ATP1B1	6.99e-07	186	119	7	08632045d499e61dd96ff29a5a9a208afe58dc58
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 SPIRE1 MYO1B LRP1B FREM1 AGBL4 ATP1B1	7.51e-07	188	119	7	4154f4787483c7e076e87a187733a9f666742c3d
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MYO6 LAPTM4B FREM1 CD44 FGFR2 MGAT5B HYDIN	7.51e-07	188	119	7	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 SPIRE1 MYO1B LRP1B FREM1 AGBL4 ATP1B1	7.78e-07	189	119	7	90aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 SPIRE1 MYO1B LRP1B FREM1 AGBL4 FGFR2	8.06e-07	190	119	7	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	COVID-19-kidney-CNT\|kidney / Disease (COVID-19 only), tissue and cell type	COBLL1 SPIRE1 MYO1B LRP1B FREM1 AGBL4 ATP1B1	8.64e-07	192	119	7	d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 COBLL1 LRP1B DNAH7 AGBL4 ATP1B1 PLEKHA7	8.95e-07	193	119	7	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 DNAH7 AGBL4 FGFR2 ATP1B1 PLEKHA7 HYDIN	9.27e-07	194	119	7	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 COBLL1 DNAH7 AGBL4 FGFR2 ATP1B1 PLEKHA7	9.27e-07	194	119	7	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ACADL MYO6 COBLL1 MYO1B BMP1 FGFR2 PLEKHA7	1.10e-06	199	119	7	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 COBLL1 SPIRE1 MYO1B LRP1B AGBL4	3.54e-06	153	119	6	9b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CYP4B1 PTGR2 MYO1B SORBS1 AGBL4 MISP	5.67e-06	166	119	6	2e4cb4056e6b0c43290a5588ff525f5f05b8beee
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CYP4B1 PTGR2 MYO1B SORBS1 AGBL4 MISP	5.67e-06	166	119	6	eb8d972326a734549675307e411fc795af66da70
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EDIL3 DNAH7 AGBL4 MAGI2 FGFR2 HYDIN	6.07e-06	168	119	6	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1B FREM1 SCG2 PTPRQ CACNA1I HYDIN	7.92e-06	176	119	6	c6484334187f64cd00cd35e77d8ae436556b4260
ToppCell	Control-Myeloid-pDC\|Control / Disease group,lineage and cell class （2021.01.30）	CUX2 GALNT3 COBLL1 MYO1B AGBL4 MED12L	7.92e-06	176	119	6	baa3563973ea1a351fe028f55828463d2a51bf1a
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_early_2\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	DNAH7 FREM1 EGFL6 MS4A8 FGFR2 HYDIN	7.92e-06	176	119	6	8e0ac3ad5e47614b4befabd674a40e3eaae553f3
ToppCell	wk_15-18-Hematologic-Myeloid-aDC_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 CD44	8.18e-06	177	119	6	ccf5dc54780d6039a4d062dee88440c011ddc0a3
ToppCell	facs-SCAT\|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 MMP27 OPCML BMP1 FAP MMP3	9.00e-06	180	119	6	6c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CUX2 COBLL1 MYO1B STAT4 MAGI2 MGAT5B	9.29e-06	181	119	6	57994ff4ecffb15653aee00644d9f887f5e3461d
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	FNIP2 MYO6 SPIRE1 FGFR2 ATP1B1 TSSK1B	9.29e-06	181	119	6	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO6 IRAG1 LRP1B MAGED2 CD44 ATP1B1	9.89e-06	183	119	6	262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO6 IRAG1 LRP1B MAGED2 CD44 ATP1B1	9.89e-06	183	119	6	c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	CYP4B1 COBLL1 MYO1B PTPRQ PEAK1 CTNND2	1.05e-05	185	119	6	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CUX2 UBE2K SORBS1 TF AGBL4 CTNND2	1.05e-05	185	119	6	1d874608aa2062024323512f68889219471b2f00
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAM OPCML BMP1 FNDC1 C1S TDRD6	1.05e-05	185	119	6	d5f5866924648a3c14e2596218fd548a31777aa3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 SPIRE1 MYO1B FREM1 AGBL4 ATP1B1	1.08e-05	186	119	6	b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	LAPTM4B MYO1B LEPR MAGI2 CD44 CACNA1I	1.12e-05	187	119	6	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	facs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 CYP4B1 DENND2D MISP FGFR2 ATP1B1	1.12e-05	187	119	6	fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCell	COVID-19-Heart-T_cell\|Heart / Disease (COVID-19 only), tissue and cell type	CUX2 GALNT3 DENND2D LRP1B OPCML STAT4	1.22e-05	190	119	6	e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCell	COPD-Epithelial\|COPD / Disease state, Lineage and Cell class	CYP4B1 SAXO2 MYO1B MS4A8 FGFR2 HYDIN	1.30e-05	192	119	6	0644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDLIM4 CEMIP FAP SCG2 CD44 C1S	1.30e-05	192	119	6	f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCell	human_hepatoblastoma-Tumor_cells-T8\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CLDN14 MYO1B SORBS1 TF LEPR LSS	1.30e-05	192	119	6	e785135262f4c9cc66c403bf362bb34643b212c5
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDLIM4 CEMIP FAP SCG2 CD44 C1S	1.30e-05	192	119	6	41a8326cd5bc19ad5041068501bab4c72399222e
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-H_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	KRT13 CYP4B1 EGFL6 PDLIM4 CEMIP MMP3	1.30e-05	192	119	6	7a6dd2ae217b8f8e460d47ad128904408299458c
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ACADL MYO6 COBLL1 SPIRE1 BMP1 FGFR2	1.34e-05	193	119	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 COBLL1 DNAH7 AGBL4 ATP1B1 PLEKHA7	1.34e-05	193	119	6	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	COVID-19-kidney-CD-PC\|kidney / Disease (COVID-19 only), tissue and cell type	COBLL1 SPIRE1 MYO1B PPARG FREM1 AGBL4	1.34e-05	193	119	6	738689d009e4b118d7ce3171a207294b95cbe78b
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IRAG1 EDIL3 EGFL6 FAP FNDC1 C1S	1.34e-05	193	119	6	5de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ACADL MYO6 COBLL1 SPIRE1 BMP1 FGFR2	1.34e-05	193	119	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM ACADL MYO6 PPARG LRP1B FREM1	1.38e-05	194	119	6	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP4B1 EGFL6 PDLIM4 MISP MAGED2 MS4A8	1.38e-05	194	119	6	40251e6415a62fa55d86f2e8609bf0402e1c1abb
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CYP4B1 SAXO2 DNAH7 AGBL4 MS4A8 HYDIN	1.38e-05	194	119	6	958e648138676d46698090b4046cb484083ae449
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLB1 GALNT3 EGFL6 FGFR2 CTNND2 ATP1B1	1.42e-05	195	119	6	5276e874615823bb00e20ff160692e0946d7d400
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FNIP2 ACADL COBLL1 BMP1 LSS ATP1B1	1.42e-05	195	119	6	d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDLIM4 FAP FNDC1 SCG2 CD44 C1S	1.42e-05	195	119	6	47762d9e442fb1f6f0033e3e10f4c6e498d2c081
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ACADL MYO6 CYP4B1 COBLL1 MYO1B FGFR2	1.42e-05	195	119	6	9406866f99555198a9be311fbd65751b70f35446
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NPR2 BMP1 FNDC1 IRS2 FGFR2 ATP1B1	1.42e-05	195	119	6	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	CYP4B1 SAXO2 DNAH7 AGBL4 MS4A8 HYDIN	1.46e-05	196	119	6	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	CYP4B1 SAXO2 DNAH7 AGBL4 MS4A8 HYDIN	1.46e-05	196	119	6	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 DNAH7 AGBL4 FGFR2 ATP1B1 PLEKHA7	1.46e-05	196	119	6	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	CYP4B1 SAXO2 DNAH7 AGBL4 MS4A8 HYDIN	1.46e-05	196	119	6	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	Severe_COVID-19-Epithelial-transitional_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	KRT13 MYO6 CYP4B1 PDLIM4 MISP MS4A8	1.50e-05	197	119	6	5ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COBLL1 MYO1B BMP1 FAP RTL1 PEAK1	1.50e-05	197	119	6	2872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDLIM4 CEMIP BMP1 FAP C1S MMP3	1.55e-05	198	119	6	229588189825b1080181db9515185677b742c668
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FNIP2 ACADL COBLL1 SPIRE1 BMP1 FGFR2	1.55e-05	198	119	6	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SORBS1 IRAG1 EDIL3 OPCML EGFL6 C1S	1.55e-05	198	119	6	dc6d9032c5029527e184ac13b887c0c1f22ef1c0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 MYO1B FREM1 STAT1 AGBL4 ATP1B1	1.55e-05	198	119	6	0d9d401190792fd61434f1b82548253187d805f0
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYP4B1 SAXO2 DNAH7 MISP MS4A8 HYDIN	1.59e-05	199	119	6	1ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ACADL MYO6 COBLL1 MYO1B FGFR2 PLEKHA7	1.59e-05	199	119	6	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	stromal_cell\|World / Lineage and Cell class	PPARG TF LEPR PDLIM4 FNDC1 C1S	1.59e-05	199	119	6	507a82d0529b5b1fa5aebcfe43db53f0b6e3f8f0
ToppCell	stromal_cell-stromal_cell\|World / Lineage and Cell class	PPARG TF LEPR PDLIM4 FNDC1 C1S	1.59e-05	199	119	6	74262363a34da3a1eb55ab375fd61ddd7bb39b23
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYP4B1 SAXO2 DNAH7 MISP MS4A8 HYDIN	1.59e-05	199	119	6	1df69c0cb5f759f6a2152521842506a75bb95cae
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ACADL MYO6 COBLL1 MYO1B FGFR2 PLEKHA7	1.59e-05	199	119	6	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYP4B1 SAXO2 DNAH7 MISP MS4A8 HYDIN	1.59e-05	199	119	6	74087b4b5e567310fc4ac58fb267ff651a180680
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYP4B1 SAXO2 DNAH7 MISP MS4A8 HYDIN	1.59e-05	199	119	6	00b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCell	PSB-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GALNT3 MYO6 CYP4B1 PDLIM4 MS4A8 ATP1B1	1.59e-05	199	119	6	58dcb0eedafa8629585dc99e53147e2287f49689
ToppCell	Mild_COVID-19-Epithelial\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CYP4B1 SAXO2 DNAH7 MISP MS4A8 HYDIN	1.59e-05	199	119	6	72689bda7476930887ae007682fcab27f956f050
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NPR2 EDIL3 CEMIP FAP MAGED2 FGFR2	1.64e-05	200	119	6	be527df943a8cedc6452ecef3cafc282db34ceb8
ToppCell	Bronchial-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GALNT3 CYP4B1 MYO1B MISP MS4A8 FGFR2	1.64e-05	200	119	6	d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCell	Lung_Parenchyma-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	GALNT3 ACADL CYP4B1 COBLL1 MYO1B FGFR2	1.64e-05	200	119	6	c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYO6 SORBS1 IRAG1 LRP1B DNAH7 FGFR2	1.64e-05	200	119	6	d0812817ef99608994193787a62d39adeb2070ca
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NPR2 EDIL3 CEMIP FAP MAGED2 FGFR2	1.64e-05	200	119	6	d254f6634895486f81d7a8b6f006fbc2679eaa5b
ToppCell	Biopsy_IPF-Epithelial-Basal\|Biopsy_IPF / Sample group, Lineage and Cell type	KRT13 CYP4B1 EDIL3 CEMIP FGFR2 ATP1B1	1.64e-05	200	119	6	5cea84581201cee7ba8141b96e65864f4fd67113
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	GALNT3 ACADL CYP4B1 COBLL1 MYO1B FGFR2	1.64e-05	200	119	6	3ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NPR2 EDIL3 CEMIP FAP MAGED2 FGFR2	1.64e-05	200	119	6	8e41a484038216f0c2ad258fd46c0e702a4bb8bf
ToppCell	distal-2-Epithelial\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP4B1 SAXO2 MISP MS4A8 ATP1B1 HYDIN	1.64e-05	200	119	6	2fc1e95706f212bf18ecdf6eb5b3182ac98c9b52
ToppCell	Biopsy_IPF-Epithelial\|Biopsy_IPF / Sample group, Lineage and Cell type	CYP4B1 SAXO2 DNAH7 MS4A8 ATP1B1 HYDIN	1.64e-05	200	119	6	76f1ac00b34d07057d8da03d276438b719b46b1d
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR2 EDIL3 CEMIP FAP MAGED2 FGFR2	1.64e-05	200	119	6	c935caef2988f165e96d8f1ef99ae8963ab9377f
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	GALNT3 ACADL CYP4B1 COBLL1 MYO1B FGFR2	1.64e-05	200	119	6	9970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYO6 SORBS1 IRAG1 LRP1B DNAH7 FGFR2	1.64e-05	200	119	6	cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCell	Healthy_donor-RBC\|Healthy_donor / disease group, cell group and cell class (v2)	MPP1 FAM161B MYO1B C1S PCSK4	5.87e-05	154	119	5	e080d5104fe6f3f6ef617bbcdccf1332ab7231e1
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PLB1 MYO1B AGBL4 BMP1 CACNA1I	6.43e-05	157	119	5	5aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAM161B EDIL3 LEPR CEMIP ATP4B	6.43e-05	157	119	5	1f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCell	AT1-AT2_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	KRT13 CYP4B1 MISP FNDC1 C1S	6.63e-05	158	119	5	3bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPIRE1 PPARG FURIN CD44 MS4A8	6.63e-05	158	119	5	6811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP4B1 LRP1B PTPRQ MINAR1 FGFR2	6.63e-05	158	119	5	d78e7e52657dc094430291fec07e9c298be9e584
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MPP1 MYO6 COBLL1 SPIRE1 LRP1B	6.83e-05	159	119	5	50d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CLDN14 MYO6 COBLL1 LRP1B ATP1B1	7.25e-05	161	119	5	4bb7bae54ba3bdf46b525c01f5ad3db8e49819cb
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP1B PTPRQ LRRC7 RIMS2 HYDIN	7.46e-05	162	119	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3-5_LINC00507_SLN\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CUX2 FNDC1 PPP4R3C PTPRQ MS4A8	7.46e-05	162	119	5	b59a0081e285cdf33de56e8b523fe0e446a198f1
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CUX2 LRP1B EGFL6 FGFR2 ATP1B1	7.46e-05	162	119	5	8e0f03fcc25b2ea777e8478fbf771699cf93719c
Disease	free androgen index	FNIP2 CUX2 COBLL1 DENND2D PPARG LEPR MINAR1 RIMS2	5.92e-05	374	105	8	EFO_0007005
Disease	calcium measurement	CLDN14 COBLL1 LAPTM4B AAK1 PPARG IRAG1 LRP1B AGBL4 HFM1 IRS2	8.36e-05	628	105	10	EFO_0004838
Disease	Malignant neoplasm of breast	VPS39 SORBS1 NDUFA3 LEPR STAT1 STAT4 SGK3 PIK3R4 BMP1 MAGED2 LRRC7 FGFR2 MMP3	1.15e-04	1074	105	13	C0006142
Disease	body fat percentage, fasting blood insulin measurement	COBLL1 PPARG	1.86e-04	6	105	2	EFO_0004466, EFO_0007800
Disease	leptin measurement	COBLL1 LRP1B OPCML FGFR2	2.04e-04	81	105	4	EFO_0005000
Disease	eosinophil count	PLB1 CUX2 PPARG DNAH7 STAT1 STAT4 FAP FNDC1 RRP12 MED12L C1S HFM1 SPIDR PEAK1 TET3	2.50e-04	1488	105	15	EFO_0004842
Disease	colorectal adenocarcinoma (is_implicated_in)	CD44 FGFR2 PCSK4	2.64e-04	35	105	3	DOID:0050861 (is_implicated_in)
Disease	serum albumin measurement	UBE2K COBLL1 LARP1B PPARG TF LEPR MTM1 CD44 FGFR2	2.70e-04	592	105	9	EFO_0004535
Disease	uric acid measurement	CLDN14 CUX2 COBLL1 AAK1 PTGR2 PPARG CEMIP FAP HFM1	3.36e-04	610	105	9	EFO_0004761
Disease	Autistic behavior	CUX2 TET3	3.46e-04	8	105	2	C0856975
Disease	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	TIMMDC1 STAT1 STAT4	3.93e-04	40	105	3	EFO_1001999, EFO_1002019, EFO_1002020
Disease	pancreatitis (implicated_via_orthology)	PPARG LEPR	4.44e-04	9	105	2	DOID:4989 (implicated_via_orthology)
Disease	coffee consumption measurement	FNIP2 CUX2 OPCML SETDB1 HYDIN	4.96e-04	182	105	5	EFO_0006781
Disease	glomerulosclerosis (implicated_via_orthology)	PPARG PLEKHA7	6.76e-04	11	105	2	DOID:0050851 (implicated_via_orthology)
Disease	waist-hip ratio, sexual dimorphism	COBLL1 PPARG	6.76e-04	11	105	2	EFO_0004343, EFO_0005951
Disease	Drug habituation	MYO6 AGBL4 EHHADH ATP1B1	7.73e-04	115	105	4	C0013170
Disease	Drug abuse	MYO6 AGBL4 EHHADH ATP1B1	7.73e-04	115	105	4	C0013146
Disease	Prescription Drug Abuse	MYO6 AGBL4 EHHADH ATP1B1	7.73e-04	115	105	4	C4316881
Disease	Substance-Related Disorders	MYO6 AGBL4 EHHADH ATP1B1	7.73e-04	115	105	4	C0236969
Disease	Drug Use Disorders	MYO6 AGBL4 EHHADH ATP1B1	7.73e-04	115	105	4	C0013222
Disease	Drug Dependence	MYO6 AGBL4 EHHADH ATP1B1	7.73e-04	115	105	4	C1510472
Disease	Substance Dependence	MYO6 AGBL4 EHHADH ATP1B1	7.73e-04	115	105	4	C0038580
Disease	Substance Use Disorders	MYO6 AGBL4 EHHADH ATP1B1	7.73e-04	115	105	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	MYO6 AGBL4 EHHADH ATP1B1	7.73e-04	115	105	4	C0029231
Disease	Substance abuse problem	MYO6 AGBL4 EHHADH ATP1B1	7.98e-04	116	105	4	C0740858
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	CLDN14 MYO6 PTPRQ	8.05e-04	51	105	3	cv:CN043650
Disease	matrix metalloproteinase measurement	MMP27 MMP3	9.54e-04	13	105	2	EFO_0004744
Disease	Skin Abnormalities	LSS FGFR2	9.54e-04	13	105	2	C0037268
Disease	obesity (implicated_via_orthology)	LEPR STAT1 STAT4 MED12L ATP4B	1.05e-03	215	105	5	DOID:9970 (implicated_via_orthology)
Disease	Intellectual Disability	RALGAPA1 CUX2 MED12L LSS FGFR2 MED23 TET3	1.11e-03	447	105	7	C3714756
Disease	hypertension (implicated_via_orthology)	MYO6 PPARG LEPR PLEKHA7	1.15e-03	128	105	4	DOID:10763 (implicated_via_orthology)
Disease	Insulin Resistance	PPARG LEPR IRS2	1.29e-03	60	105	3	C0021655
Disease	Insulin Sensitivity	PPARG LEPR IRS2	1.29e-03	60	105	3	C0920563
Disease	Synostotic Posterior Plagiocephaly	FREM1 FGFR2	1.46e-03	16	105	2	C1833340
Disease	Craniosynostosis, Type 1	FREM1 FGFR2	1.46e-03	16	105	2	C4551902
Disease	Acrocephaly	FREM1 FGFR2	1.46e-03	16	105	2	C0030044
Disease	Trigonocephaly	FREM1 FGFR2	1.46e-03	16	105	2	C0265535
Disease	Scaphycephaly	FREM1 FGFR2	1.46e-03	16	105	2	C0265534
Disease	Synostotic Anterior Plagiocephaly	FREM1 FGFR2	1.46e-03	16	105	2	C2931150
Disease	body mass index, type 2 diabetes mellitus	COBLL1 PPARG	1.46e-03	16	105	2	EFO_0004340, MONDO_0005148
Disease	Metopic synostosis	FREM1 FGFR2	1.46e-03	16	105	2	C1860819
Disease	MAJOR AFFECTIVE DISORDER 2	CUX2 MAGI2	1.65e-03	17	105	2	C1839839
Disease	Muscle hypotonia	RALGAPA1 LSS	1.65e-03	17	105	2	C0026827
Disease	body fat percentage, type 2 diabetes mellitus	COBLL1 PPARG	1.65e-03	17	105	2	EFO_0007800, MONDO_0005148
Disease	Renal Insufficiency	PPARG LEPR	1.65e-03	17	105	2	C1565489
Disease	Brachycephaly	FREM1 FGFR2	1.65e-03	17	105	2	C0221356
Disease	cognitive function measurement	GALNT3 MAGEB18 FAM161B PPARG LRP1B OPCML CEMIP FAP MED12L CACNA1I LRRC7 CTNND2 HYDIN	1.74e-03	1434	105	13	EFO_0008354
Disease	type 1 diabetes mellitus	PLB1 CUX2 LRP1B STAT4 FAP	1.77e-03	242	105	5	MONDO_0005147
Disease	essential hypertension (is_implicated_in)	NPR2 ATP1B1	1.85e-03	18	105	2	DOID:10825 (is_implicated_in)
Disease	BMI-adjusted fasting blood insulin measurement	COBLL1 PPARG	1.85e-03	18	105	2	EFO_0008037
Disease	Lipoidosis	PPARG LSS	2.06e-03	19	105	2	C0023794
Disease	glomerulonephritis (is_marker_for)	TF MMP3	2.06e-03	19	105	2	DOID:2921 (is_marker_for)
Disease	stomach cancer (is_implicated_in)	LRP1B FGFR2 ATP4B	2.19e-03	72	105	3	DOID:10534 (is_implicated_in)
Disease	Craniosynostosis	FREM1 FGFR2	2.29e-03	20	105	2	C0010278
Disease	Nonsyndromic genetic hearing loss	CLDN14 MYO6 PTPRQ	2.55e-03	76	105	3	cv:C5680182
Disease	Kidney Failure	PPARG LEPR	2.77e-03	22	105	2	C0035078
Disease	Ovarian Serous Adenocarcinoma	NEK7 FGFR2	3.02e-03	23	105	2	C1335177
Disease	idiopathic pulmonary fibrosis (is_marker_for)	FGFR2 MMP3	3.02e-03	23	105	2	DOID:0050156 (is_marker_for)
Disease	alcohol drinking	CUX2 TF CTNND2	3.05e-03	81	105	3	EFO_0004329
Disease	Nonsyndromic Deafness	CLDN14 MYO6 CEMIP	3.05e-03	81	105	3	C3711374
Disease	hematocrit	RALGAPA1 CLDN14 COBLL1 AAK1 SPIRE1 SORBS1 PPARG IRAG1 IRS2 HYDIN	3.26e-03	1011	105	10	EFO_0004348
Disease	partial thromboplastin time	CUX2 C1S	3.29e-03	24	105	2	EFO_0004310
Disease	Dyslipidemias	PPARG LEPR	3.29e-03	24	105	2	C0242339
Disease	Dyslipoproteinemias	PPARG LEPR	3.29e-03	24	105	2	C0598784
Disease	systemic scleroderma (is_implicated_in)	STAT4 MMP3	3.29e-03	24	105	2	DOID:418 (is_implicated_in)
Disease	type 2 diabetes mellitus (is_implicated_in)	SORBS1 PPARG LEPR IRS2	3.30e-03	171	105	4	DOID:9352 (is_implicated_in)
Disease	alkaline phosphatase measurement	RALGAPA1 CUX2 GALNT3 NEK7 MYO1B LARP1B PPARG LEPR HFM1 CHPF2	3.36e-03	1015	105	10	EFO_0004533
Disease	coronary artery disease	CUX2 AAK1 IRAG1 BMP1 FAP FNDC1 FURIN C1S LRRC7 ATP1B1 PLEKHA7	3.52e-03	1194	105	11	EFO_0001645
Disease	hypothyroidism	PPARG TIMMDC1 STAT4 FAP CD44	3.52e-03	284	105	5	EFO_0004705

Protein segments in the cluster

Peptide	Gene	Start	Entry
LEPFRVEQAPPVIYY	ALKBH6	11	Q3KRA9
REGNLKRYPTPYPDE	ERBIN	476	Q96RT1
RPNDPKSYEAYVLNI	ATP1B1	91	P05026
TPTPKVNLQPFNYEE	EGFL6	306	Q8IUX8
YPIAKAYVDARVQPI	ACADL	396	P28330
PDPDKRPDIYQVSYF	AAK1	296	Q2M2I8
PYKYPRKVEFVQELP	ACSM4	546	P0C7M7
ITYREPPNPEYQEFQ	NPR2	296	P20594
EALRKAYQLEPYPSQ	CUX2	1181	O14529
VDPYTPDYQDQLRSP	ATP4B	66	P51164
QPRELGQPLQVKYYP	ATP4B	206	P51164
IQSPNYPDDYRPSKV	BMP1	446	P13497
ITEDSYPGYIPKPRQ	CEMIP	651	Q8WUJ3
YNPKPKPSNEITREY	COBLL1	711	Q53SF7
PQEPSRKDYETYQPF	CTNND2	1146	Q9UQB3
KAEETRYPQQYQPSP	RBM15B	491	Q8NDT2
VPDYELKYPPVSSER	OCEL1	146	Q9H607
LPPRYQPDVKFIQVD	HACL1	291	Q9UJ83
EEPPTKYQISQPEVY	FGFR2	36	P21802
KVNRIPPDAYQPYLS	MISP	416	Q8IVT2
PNYVSLDPRKYPLSQ	MMP27	236	Q9H306
RSQKELPTEPPYTAY	EIF4H	31	Q15056
PIRPYENPRYFKNVI	LRP1B	2211	Q9NZR2
VDEYPQSNIYRVPPN	MED12L	1781	Q86YW9
KYEQVPNSDPPRYQF	MAGEB1	256	P43366
LEYQQVPSSDPPRYE	MAGEB17	256	A8MXT2
LKYLEYQQVPNSDPP	MAGEB18	251	Q96M61
YQQVPNSDPPRYEFL	MAGEB18	256	Q96M61
LDYARVPNSNPPEYE	MAGED2	426	Q9UNF1
PYPAPVYSQPEELKE	MAGI2	271	Q86UL8
YDPTNKRYEVPVPLN	MGAM2	1011	Q2M2H8
VEINLKRYPTPYPED	LRRC7	561	Q96NW7
EDARQPAKPPYSYIA	FOXD4L4	101	Q8WXT5
EDARQPAKPPYSYIA	FOXD4L3	101	Q6VB84
YDPNNNRYEVPVPLN	MGAM	1951	O43451
YRIVNYTPDLPKDAV	MMP3	116	P08254
LKQSPASPERDYSPY	KRT13	141	P13646
KYYRQNPDIPQLEPS	EHHADH	681	Q08426
QKENFDPLQYPETTP	IRAG1	281	Q9Y6F6
YYESQRPPEVPAFVK	MGAT5B	496	Q3V5L5
NDYDPDPQPRYTPSK	PCSK4	181	Q6UW60
PYRVVNLEQPLCKPY	PEAK1	461	Q9H792
NPDPEKRPDVTYVYD	NEK7	276	Q8TDX7
YDLNITVYPVDNQPP	FREM1	1011	Q5H8C1
SDYYNFQKPRPSEVP	GAPT	131	Q8N292
SQVPDNPPDYQKYYR	LSS	421	P48449
LLYPEKEYIPVPDIN	MED23	401	Q9ULK4
YPNSIQEYIRQLPPN	LAPTM4B	216	Q86VI4
PRVNPVVPDYEGLYK	FAM161B	366	Q96MY7
PLVPFPLQYQVKYSE	LEPR	261	P48357
KPDAVQPDSLPYPQY	MED29	146	Q9NX70
PPNPNGRIISYIVKY	PTPRQ	121	Q9UMZ3
IPPDRPYGKYQETLI	PPP4R3C	56	Q6ZMV5
PEIYGKVRQEPSEYQ	HFM1	1241	A2PYH4
PDVRKVKITVNYPPY	OPCML	211	Q14982
SDPNLARYPVKPQPY	RIMS2	366	Q9UQ26
SAPQPPRLEYYESEK	IRS2	66	Q9Y4H2
TPPIKAQYVRLYPQV	EDIL3	286	O43854
YPYICQDPKVVFPQR	HYDIN	2791	Q4G0P3
VQKGEYRTNPEDIYP	CD44	156	P16070
YQPPAAYKDNRAPSV	CLDN14	211	O95500
YYTAAELKPVLDRPP	GALNT3	101	Q14435
NIYPEVYVPDLNPVI	GALNT3	491	Q14435
VAPYVTYLNKDPSAP	FNDC1	1611	Q4ZHG4
KRDVYQEPTDPKFPQ	FURIN	106	P09958
EQLPKYQYTRPASDV	FNIP2	121	Q9P278
TIQGDVALPPYYQPE	CACNA1I	246	Q9P0X4
NYIPNPDFVPEKIRN	DNAH7	2771	Q8WXX0
EIASPNYPKPYPENS	C1S	186	P09871
DYYRLNPVVEKVAIP	AGBL4	436	Q5VU57
YPNIYAANPVITPEP	MS4A8	221	Q9BY19
DARQPAKPPYSYIAL	FOXD4L1	101	Q9NU39
YPLPYLQPEPQKNER	CUL9	476	Q8IWT3
KESFRLYPPVPQVYR	CYP4B1	371	P13584
NPEKFVYPVPYTTRP	MPP1	306	Q00013
EYLAPEVIRKQPYDN	SGK3	326	Q96BR1
YEPIITYQFPKRENL	DENND2D	71	Q9H6A0
QDPNKTPRFYPVVKE	LARP1B	611	Q659C4
LYKIYIQPQSPREIN	RGS13	86	O14921
QYLNPVYSPVPDKRR	MINAR1	311	Q9UPX6
YEKPYPQPVQSVDGS	RTL1	451	A6NKG5
YPDIRIEGENYLPQP	SELENOT	66	P62341
PPEELVPYYTDAKNR	MRPL15	206	Q9P015
AENIPENPLKYLYPN	STAT1	656	P42224
VKTRPEYYVGPPLQR	TDRD6	1341	O60522
KKDYNPYPVCRVDPI	SAXO1	106	Q8IYX7
TQLRFKPAYNPYTEP	FARSA	401	Q9Y285
EDARQPAKPPYSYIA	FOXD4L5	101	Q5VV16
EDARQPAKPPYSYIA	FOXD4L6	101	Q3SYB3
KPPEGYDVVAVYPNA	PDLIM4	311	P50479
EYQSAIKVEPASPPY	PPARG	101	P37231
PPPRNLPSDYKYAQD	PLEKHA7	486	Q6IQ23
SYFPNPYNQEKVLPR	SCG2	451	P13521
PYNQEKVLPRLPYGA	SCG2	456	P13521
PRNSNYTYPIKPAIE	PLB1	1051	Q6P1J6
GRPDPYAYIPLNRSK	RRP12	1246	Q5JTH9
DPYVLVDRKFQPYKP	SETDB1	661	Q15047
EDFKPRIVPYYRDPN	CHPF2	66	Q9P2E5
VPRNDINIYPEYILP	PIK3R4	451	Q99570
DEQYPRTINIPYPKA	FAP	241	Q12884
NRPPLSDKNIEQYFP	FYTTD1	121	Q96QD9
VYDAYLAPNNLKPVV	TF	86	P02787
YVPRLQIYQPDSPLK	RALGAPA1	1346	Q6GYQ0
NPFYTKEINRVLYPV	MTM1	511	Q13496
IIDEDPIYKLYQPPV	SPIDR	616	Q14159
QYNVLPAPVPKYASR	STPG4	141	Q8N801
ERQYNPLPIEYQLTP	SPIRE1	291	Q08AE8
ENIPENPLKYLYPDI	STAT4	651	Q14765
EERQKRLPYVPEPYY	TIMMDC1	36	Q9NPL8
NRDTPEENPYFPTYK	SORBS1	406	Q9BX66
PEIVKSPSDPKQYRY	NRDC	101	O43847
TEVAPLYKRLAPQAY	TET3	1026	O43151
RINNKYDETYPPLPV	PLAAT1	81	Q9HDD0
YCPYEIVKQPRHVPE	SAXO2	21	Q658L1
NKATPYNYPVPVRDD	NDUFA3	46	O95167
YQLEIKIPETYPFNP	UBE2K	56	P61086
YAAPEVLQGIPYQPK	TSSK1B	181	Q9BXA7
YAAPEVLQSIPYQPK	TSSK2	181	Q96PF2
ISQYNKDVPYPPPLS	PTGR2	256	Q8N8N7
PLSPYLNVDPRYLVQ	TIMM23	41	O14925
LLPTDYRKQLQYPNP	VPS39	386	Q96JC1
NPYRSLPIYSPEKVE	MYO1B	56	O43795
RIPFIRPADQYKDPQ	MYO6	1181	Q9UM54