Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponenteukaryotic translation initiation factor 3 complex, eIF3m

EIF3C EIF3CL

7.61e-059312GO:0071541
GeneOntologyCellularComponentWASH complex

DNAJC13 WASHC5

2.21e-0415312GO:0071203
GeneOntologyCellularComponenteukaryotic translation initiation factor 3 complex

EIF3C EIF3CL

2.52e-0416312GO:0005852
GeneOntologyCellularComponenteukaryotic 48S preinitiation complex

EIF3C EIF3CL

3.21e-0418312GO:0033290
GeneOntologyCellularComponenteukaryotic 43S preinitiation complex

EIF3C EIF3CL

3.58e-0419312GO:0016282
GeneOntologyCellularComponenttranslation preinitiation complex

EIF3C EIF3CL

3.98e-0420312GO:0070993
GeneOntologyCellularComponentclathrin adaptor complex

AP2M1 AP4M1

9.64e-0431312GO:0030131
GeneOntologyCellularComponentAP-type membrane coat adaptor complex

AP2M1 AP4M1

2.30e-0348312GO:0030119
GeneOntologyCellularComponentclathrin coat

AP2M1 AP4M1

3.12e-0356312GO:0030118
GeneOntologyCellularComponentaxoneme

CFAP61 HYDIN KIF19

3.51e-03207313GO:0005930
GeneOntologyCellularComponentciliary plasm

CFAP61 HYDIN KIF19

3.55e-03208313GO:0097014
MousePhenoabnormal hallux morphology

EIF3C EIF3CL

3.32e-055262MP:0009049
DomainEIF3C_N_dom

EIF3C EIF3CL

2.67e-062312IPR008905
DomaineIF-3c_N

EIF3C EIF3CL

2.67e-062312PF05470
DomainEIF3C

EIF3C EIF3CL

2.67e-062312IPR027516
DomainClathrin_mu_CS

AP2M1 AP4M1

3.98e-056312IPR018240
DomainCLAT_ADAPTOR_M_1

AP2M1 AP4M1

3.98e-056312PS00990
DomainCLAT_ADAPTOR_M_2

AP2M1 AP4M1

3.98e-056312PS00991
DomainClathrin_mu

AP2M1 AP4M1

1.19e-0410312IPR001392
DomainAdap_comp_sub

AP2M1 AP4M1

1.45e-0411312PF00928
DomainMHD

AP2M1 AP4M1

2.06e-0413312IPR028565
DomainMHD

AP2M1 AP4M1

2.06e-0413312PS51072
DomainClat_adaptor_s

AP2M1 AP4M1

3.15e-0416312PF01217
DomainPINT

EIF3C EIF3CL

3.15e-0416312SM00088
DomainAP_mu_sigma_su

AP2M1 AP4M1

3.15e-0416312IPR022775
DomainPCI

EIF3C EIF3CL

3.57e-0417312PF01399
DomainPCI_dom

EIF3C EIF3CL

3.57e-0417312IPR000717
DomainLongin-like_dom

AP2M1 AP4M1

9.81e-0428312IPR011012
DomainTPR_1

TTC32 SH3TC1

9.75e-0390312PF00515
DomainTPR_1

TTC32 SH3TC1

9.75e-0390312IPR001440
DomainP-loop_NTPase

ARHGAP35 DICER1 HYDIN KIF19 AGAP3

1.21e-02848315IPR027417
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

KRT78 DNAJC13 AP2M1 EIF3C SF3B1 ARHGAP35 SBF1 WASHC5 EIF3CL AGAP3

3.79e-071431321037142655
Pubmed

EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.

EIF3C EIF3CL

8.20e-07232236157221
Pubmed

Identification of two new mu-adaptin-related proteins, mu-ARP1 and mu-ARP2.

AP2M1 AP4M1

8.20e-0723229013859
Pubmed

BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs.

ZBTB16 IL6

8.20e-07232225605927
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

KRT78 DNAJC13 AP2M1 EIF3C SF3B1 ARHGAP35 SBF1 RBM12B

4.63e-06108232838697112
Pubmed

Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies.

EIF3C EIF3CL

4.92e-06432210504338
Pubmed

TL1A induces TCR independent IL-6 and TNF-α production and growth of PLZF⁺ leukocytes.

ZBTB16 IL6

4.92e-06432224416448
Pubmed

RME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation.

DNAJC13 WASHC5

8.19e-06532224643499
Pubmed

Subunit-specific regulation of NMDA receptor endocytosis.

AP2M1 AP4M1

1.72e-05732215254094
Pubmed

The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling.

EIF3C EIF3CL

2.94e-05932221292980
Pubmed

The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.

EIF3C EIF3CL

2.94e-05932224003236
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

KRT78 DNAJC13 SBF1 DICER1

3.50e-0520232433005030
Pubmed

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.

EIF3C EIF3CL

3.67e-051032216286006
Pubmed

Conservation and diversity of eukaryotic translation initiation factor eIF3.

EIF3C EIF3CL

3.67e-05103228995409
Pubmed

DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis.

DNAJC13 EIF3C EIF3CL

3.71e-057032334255829
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

MRPL28 AP2M1 EIF3C RBM12B DICER1 EIF3CL

4.52e-0572332634133714
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

KRT78 DNAJC13 ARHGAP35 SBF1 DICER1 NOSIP

4.55e-0572432636232890
Pubmed

Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3.

EIF3C EIF3CL

5.38e-051232214519125
Pubmed

Reconstitution reveals the functional core of mammalian eIF3.

EIF3C EIF3CL

5.38e-051232217581632
Pubmed

The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A.

AP2M1 AP4M1

6.36e-051332232073997
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

AP2M1 EIF3C SF3B1 ARHGAP35 WASHC5 EIF3CL AGAP3

6.51e-05113932736417873
Pubmed

Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

EIF3C EIF3CL

7.41e-051432218599441
Pubmed

Scanning the human proteome for calmodulin-binding proteins.

DNAJC13 EIF3C SF3B1

8.40e-059232315840729
Pubmed

Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

EIF3C EIF3CL

8.55e-051532217322308
Pubmed

Controlling tissue patterning by translational regulation of signaling transcripts through the core translation factor eIF3c.

EIF3C EIF3CL

1.11e-041732234752747
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

MRPL28 KRT78 AP2M1 SF3B1 RBM12B EIF3CL NOSIP

1.21e-04125732736526897
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

KRT78 DNAJC13 AP2M1 EIF3C SF3B1 WASHC5 NOSIP

2.02e-04136732732687490
Pubmed

Dicer is required for Sertoli cell function and survival.

ZBTB16 DICER1

2.24e-042432219876815
Pubmed

Genetic loci influencing natural variations in femoral bone morphometry in mice.

EIF3C EIF3CL

2.84e-042732211518254
Pubmed

The AP-3 complex: a coat of many colours.

AP2M1 AP4M1

3.05e-04283229714600
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

AP2M1 EIF3C SF3B1 RBM12B NOSIP

3.19e-0466032532780723
Pubmed

BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.

ZBTB16 SF3B1

3.75e-043132223086144
Pubmed

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.

MRPL28 MGAT2 DICER1 AGAP3 NOSIP

3.81e-0468632528380382
Pubmed

USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells.

AP2M1 RBM12B

4.79e-043532233378683
Pubmed

Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.

AP4M1 SBF1 DICER1

4.87e-0416732325659891
Pubmed

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.

AP2M1 ARHGAP35 EIF3CL

5.04e-0416932331462741
Pubmed

Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC.

EIF3C EIF3CL

5.07e-043632216097034
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

AP2M1 EIF3C SF3B1 WASHC5 YIPF4 EIF3CL

5.72e-04115532620360068
Pubmed

Quantitative study of the interactome of PKCζ involved in the EGF-induced tumor cell chemotaxis.

MRPL28 DNAJC13 DICER1

6.45e-0418432323402259
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DNAJC13 EIF3C SF3B1 ARHGAP35 EIF3CL

6.59e-0477432515302935
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC32 SH3TC1

7.78e-03115212769
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SBF1 AGAP3

2.35e-02206212682
CoexpressionBILANGES_SERUM_SENSITIVE_VIA_TSC2

EIF3C DICER1 EIF3CL

8.00e-0632323MM1307
CoexpressionGSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN

MGAT2 ZBTB16 ARHGAP35 SH3TC1

9.62e-05198324M6511
CoexpressionGSE9601_NFKB_INHIBITOR_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP

MRPL28 AP2M1 C11orf54 SEC14L1

1.00e-04200324M6884
CoexpressionGSE17721_LPS_VS_CPG_8H_BMDC_UP

DNAJC13 ARHGAP35 DICER1 IL6

1.00e-04200324M4003
CoexpressionFOSTER_KDM1A_TARGETS_DN

AP2M1 EIF3C EIF3CL SEC14L1

1.10e-04205324MM957
ToppCellControl_saline-Epithelial_airway-airway_epithelial|Control_saline / Treatment groups by lineage, cell group, cell type

KRT78 CFAP61 HYDIN KIF19

1.04e-05198314e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCellControl_saline-Epithelial_airway|Control_saline / Treatment groups by lineage, cell group, cell type

KRT78 CFAP61 HYDIN KIF19

1.04e-05198314e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 THSD1 IL6 SEC14L1

1.06e-051993148db1acdcabf97f01b9ca17456c48ec8ac4928390
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CFAP61 HYDIN SEC14L1

1.32e-041433135fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCellCOVID-19-kidney-Mito-rich_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DCLK3 KRT78 SEC14L1

1.38e-04145313afed661aef990edb8e7012ab67ace56443520c9f
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 AP4M1 RBM12B

1.49e-04149313defe2e4a2f3118f8b42e99a4f2bf03e54c1b698f
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP61 HYDIN KIF19

1.65e-041543137556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP61 HYDIN KIF19

1.65e-041543134e3bc24043144143842627cacf6f90dda2228910
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP61 HYDIN KIF19

1.68e-041553135f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP61 HYDIN KIF19

1.68e-041553130944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SH3TC1 TRMT2B KIF19

1.84e-0416031333050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AP4M1 HYDIN LRRC17

1.91e-0416231356f1789e69a6cb29956e46aba92b290847327c1f
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

ZBTB16 THSD1 SEC14L1

2.24e-04171313bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP61 HYDIN KIF19

2.65e-04181313dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASIC2 HYDIN LRRC17

2.74e-04183313f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 SF3B1 IL6

2.82e-04185313eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellP28-Epithelial-airway_epithelial_cell-club_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP61 HYDIN KIF19

2.87e-04186313a26811481668fa25c48a064a56c198685693ad8d
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 SH3TC1 IL6

2.87e-04186313e3a14f3ccadbf3211822c67b8956ee01f563307a
ToppCellP28-Epithelial-airway_epithelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP61 HYDIN KIF19

2.87e-04186313df80f101954b8ec6ccdb03e702de22e70b65181f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRT78 THSD1 SEC14L1

2.92e-041873130ef82111b9049cc7ee78d64d240e1f10ab14d6b6
ToppCelltumor_Lung-Epithelial_cells-tS3|Epithelial_cells / Location, Cell class and cell subclass

CFAP61 HYDIN KIF19

2.92e-041873133cea677279e71fdb9879530dea10a5e6393beacd
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

CFAP61 HYDIN KIF19

2.96e-0418831361a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP61 HYDIN KIF19

2.96e-041883132b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP61 HYDIN KIF19

3.01e-0418931368a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellCOPD-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

ZBTB16 SH3TC1 SEC14L1

3.05e-04190313aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCellfacs-Lung-nan-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP61 HYDIN KIF19

3.05e-04190313e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCellIPF-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

ZBTB16 SH3TC1 SEC14L1

3.05e-04190313f9c2a13c7f6460e3b348581be855b7281c8f70b5
ToppCellfacs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP61 HYDIN KIF19

3.05e-04190313fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP61 HYDIN KIF19

3.10e-04191313649fcb62ad15de2f83e61591e43923a717664ae7
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP61 HYDIN KIF19

3.10e-041913139621e22e14ea069f22713947c9faa2d882abe5fe
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAT2 EIF3C C11orf54

3.10e-0419131360c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAT2 EIF3C C11orf54

3.10e-0419131309db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAT2 EIF3C C11orf54

3.10e-04191313973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellCiliated-cil-3|World / Class top

CFAP61 HYDIN KIF19

3.15e-041923134989ebb8812b8af1870599acd932849122c05a29
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZBTB16 THSD1 SEC14L1

3.20e-04193313ff6e6b825d6c88148216c601580be3c28851ab5c
ToppCellCOPD-Myeloid-ncMonocyte|COPD / Disease state, Lineage and Cell class

ZBTB16 SH3TC1 SEC14L1

3.20e-04193313936ca95995599356b794fba32bfd82d8de339365
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 THSD1 SEC14L1

3.25e-04194313f159ef8541d75a4e98468947f231bb463bec922c
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Ciliated|Control_saline / Treatment groups by lineage, cell group, cell type

CFAP61 HYDIN KIF19

3.30e-0419531360067b5359174f0d1a8b5748bfc0690762e9e740
ToppCellControl-Myeloid-ncMonocyte|Control / Disease state, Lineage and Cell class

ZBTB16 SH3TC1 SEC14L1

3.30e-04195313fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCell3'-Distal_airway-Endothelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 IL6 SEC14L1

3.40e-041973139ffb823c0f3f23cc85f9fd3ca24f77817e90bd86
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SH3TC1 IL6 SEC14L1

3.40e-0419731331bec97c3952c48031bd66a5dad16a70a61519c3
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 IL6 SEC14L1

3.40e-041973136ac8d3e3f573e3848ab33e4df66dfaf8f948ea6c
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 IL6 SEC14L1

3.40e-04197313e3be7758a92f12e0a423394822957e1b7f995110
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 IL6 SEC14L1

3.45e-041983135eedcc20e35adbabe268a93b748ee4566b3ffb66
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 IL6 SEC14L1

3.45e-041983133aae7d146ebbb34da3239041a7c0334abff2597f
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Airway-Club|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KRT78 CFAP61 KIF19

3.45e-041983136712216c5a7fd86b68fd45b0ff7794975f19774e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ASIC2 HYDIN KIF19

3.50e-0419931319a97e27a4758e794ce7246d295e112b47931a48
ToppCell3'-Parenchyma_lung-Endothelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 IL6 SEC14L1

3.50e-04199313920299626a9ec8e50d944f5a7667e855de7edd72
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 IL6 SEC14L1

3.50e-04199313ddfb725ccbcadbd188e20b60a7567e1f8245f18d
ToppCelldistal-1-Endothelial-Capillary|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZBTB16 THSD1 SEC14L1

3.50e-041993134b22769882fdd83f9cdca59e4d39ef441e62856b
ToppCelldistal-Endothelial-Capillary-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZBTB16 THSD1 SEC14L1

3.50e-04199313d27fbd9a651821b2859dfa80bce4e6fc6f8299fc
ToppCellLPS_anti-TNF-Epithelial_airway|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KRT78 HYDIN KIF19

3.50e-041993136aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCelltumor_Lung-Endothelial_cells-Tip-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

ZBTB16 THSD1 SEC14L1

3.50e-0419931380c8641cfd84436eadf2234f1313749e2f73331f
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KRT78 HYDIN KIF19

3.50e-0419931360919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 THSD1 SEC14L1

3.50e-041993136cfe5a3d0ad530411ebc11decb4ab4c529e018d5
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 THSD1 SEC14L1

3.55e-04200313ec9a18576a3d08ddfceb70d114c4ab861fbb0d08
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 THSD1 SEC14L1

3.55e-042003133767abc75176779198505ebc6967d55ce322d9fe
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP61 HYDIN KIF19

3.55e-0420031352aef65f01b06cd98056f17977efe525aee6eb6f
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 IL6 SEC14L1

3.55e-0420031324fa22fb93c4533a79e5d95d241a60f4b13e5631
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP61 HYDIN KIF19

3.55e-0420031312bc7d95c4166d12487081a76d210b7abe5991b0
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 THSD1 SEC14L1

3.55e-04200313e0a003d2a5fd6adfcb817c9bc5dceb9c79e7491b
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Endothelial|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ZBTB16 IL6 SEC14L1

3.55e-042003132ae62c428728c1d9d4471d4be24bd6ab074fa22c
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP61 HYDIN KIF19

3.55e-0420031355c148238d5c80c1faa3428a917ae8075be2c145
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KRT78 HYDIN KIF19

3.55e-04200313cf191104484bfb2b9f87de416b9453135f8833c1
ToppCelldistal-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZBTB16 IL6 SEC14L1

3.55e-042003137a355c3883fd409b2e0868164bb6e7ce4b745776
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZBTB16 THSD1 SEC14L1

3.55e-0420031324e43d3d16d07571f77e0cd5b2e4758c6ff802cb
ToppCellproximal-Endothelial-Bronchial_Vessel_2-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

THSD1 IL6 SEC14L1

3.55e-04200313b6666ade237c39bfde13987685567bad1762baec
ToppCellproximal-Endothelial-Bronchial_Vessel_2|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

THSD1 IL6 SEC14L1

3.55e-042003132ecf7a38799c151ffb09f2677e38a4ffa354c1da
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP61 HYDIN KIF19

3.55e-0420031306ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP61 HYDIN KIF19

3.55e-04200313926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP61 HYDIN KIF19

3.55e-0420031385c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

KRT78 HYDIN KIF19

3.55e-04200313da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellLPS_IL1RA-Epithelial_airway|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KRT78 HYDIN KIF19

3.55e-04200313a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCelldistal-Endothelial-Capillary-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZBTB16 IL6 SEC14L1

3.55e-04200313ab96d3d801373459a2503ccfb665dc3f43bfb5a1
ToppCellproximal-3-Endothelial-Bronchial_Vessel_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

THSD1 IL6 SEC14L1

3.55e-04200313038812912bb9f6c1359765614bb9fd138843a306
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

KRT78 HYDIN KIF19

3.55e-0420031372c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
DrugCP-690334-01 [459212-38-5]; Down 200; 10uM; MCF7; HT_HG-U133A

MGAT2 SF3B1 ARHGAP35 SBF1 SH3TC1 SEC14L1

2.59e-071933263906_DN
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A

SF3B1 THSD1 RBM12B DICER1 SEC14L1

6.60e-061913254279_DN
DrugDipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A

MGAT2 SF3B1 SBF1 SH3TC1 SEC14L1

7.31e-061953253835_DN
Diseasecortical surface area measurement

DNAJC13 ZBTB16 SF3B1 IL6 YIPF4 AGAP3 NOSIP

2.60e-041345297EFO_0010736
Diseasehepatocellular carcinoma (is_implicated_in)

SF3B1 DICER1 IL6

7.38e-04181293DOID:684 (is_implicated_in)
DiseaseThyroid carcinoma

DICER1 IL6

8.60e-0444292C0549473
DiseaseChronic Lymphocytic Leukemia

SF3B1 IL6

1.34e-0355292C0023434
Diseasepolycystic ovary syndrome

ZBTB16 ASIC2

1.59e-0360292EFO_0000660

Protein segments in the cluster

PeptideGeneStartEntry
NIYAIYDLIERIEDL

AGAP3

46

Q96P47
ILKETYGEYFLAELI

CFAP61

206

Q8NHU2
YQRLEFLGDAILDYL

DICER1

1701

Q9UPY3
VALVYELLDEVLDYG

AP4M1

106

O00189
TILELFDYIYELIKE

ASIC2

446

Q16515
ADFLLAEDDIYLLYD

RBM12B

421

Q8IXT5
DGYLYEREAILEYIL

NOSIP

61

Q9Y314
YAGLILFLEEDHYLA

MGAT2

251

Q10469
FDYGVLEDLYFLKLL

LRRC17

331

Q8N6Y2
EIYLILEYVQGGDLF

DCLK3

426

Q9C098
ELEGKLEALREYLYF

KRT78

231

Q8N1N4
VLIYELLDEILDFGY

AP2M1

106

Q96CW1
LDSDYERIELGLLYE

SBF1

1526

O95248
ELYEVYLRELEEGSL

KIF19

631

Q2TAC6
YIRILADLEDYLNEL

EIF3C

106

Q99613
YIRILADLEDYLNEL

EIF3CL

106

B5ME19
EYILDFGYIILGEVR

HYDIN

1596

Q4G0P3
KIGDYYLRLLLEEDE

DNAJC13

826

O75165
EIIEYYLRQLEEEGI

SEC14L1

161

Q92503
ITGLLEFEVYLEYLQ

IL6

116

P05231
YQLLFGEPYIFEELL

TRMT2B

296

Q96GJ1
VKVYLVLGDIIFYDL

SH3TC1

1236

Q8TE82
LLEYSELFYELELDA

ARHGAP35

496

Q9NRY4
DIVEYLGYFLPAEFL

C11orf54

286

Q9H0W9
DVVGALLFLEDYVRY

WASHC5

1121

Q12768
DLLYAAEILEIEYLE

ZBTB16

101

Q05516
VVLYEYLGEEYPEVL

SF3B1

976

O75533
LCDYVLGEAEYLLLR

THSD1

16

Q9NS62
TLDLIDEAYGLDFYI

MRPL28

131

Q13084
ILYRLGYFDDALEDF

TTC32

101

Q5I0X7
PLLEELDIDLKDIYY

YIPF4

76

Q9BSR8
ELAIQFYEIQLELYE

WHAMMP3

111

Q1A5X7