Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

FZD6 TAAR9 CASR ADGRL2 ADGRL3

1.89e-03884215GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

FZD6 IL12RB1 TAAR9 CASR ADGRL2 ADGRL3

2.14e-031353216GO:0004888
DomainLatrophilin

ADGRL2 ADGRL3

4.35e-063232PF02354
DomainGPCR_2_latrophilin_rcpt_C

ADGRL2 ADGRL3

4.35e-063232IPR003334
DomainLectin_gal-bd_dom

ADGRL2 ADGRL3

1.45e-055232IPR000922
DomainGal_Lectin

ADGRL2 ADGRL3

1.45e-055232PF02140
DomainSUEL_LECTIN

ADGRL2 ADGRL3

1.45e-055232PS50228
DomainGPCR_2_latrophilin

ADGRL2 ADGRL3

1.45e-055232IPR003924
DomainGPCR_2-like

FZD6 ADGRL2 ADGRL3

5.33e-0560233IPR017981
DomainGPCR_2_secretin-like

FZD6 ADGRL2 ADGRL3

5.33e-0560233IPR000832
DomainG_PROTEIN_RECEP_F2_4

FZD6 ADGRL2 ADGRL3

5.60e-0561233PS50261
DomainGAIN_dom_N

ADGRL2 ADGRL3

7.92e-0511232IPR032471
DomainGAIN

ADGRL2 ADGRL3

7.92e-0511232PF16489
DomainOlfac-like_dom

ADGRL2 ADGRL3

1.12e-0413232IPR003112
DomainOLF

ADGRL2 ADGRL3

1.12e-0413232SM00284
DomainOLF

ADGRL2 ADGRL3

1.12e-0413232PF02191
DomainOLF

ADGRL2 ADGRL3

1.12e-0413232PS51132
DomainNPIP

NPIPB8 NPIPB6

1.31e-0414232IPR009443
DomainHormR

ADGRL2 ADGRL3

4.28e-0425232SM00008
DomainHRM

ADGRL2 ADGRL3

5.38e-0428232PF02793
DomainGPS

ADGRL2 ADGRL3

7.95e-0434232SM00303
DomainGPCR_2_secretin-like_CS

ADGRL2 ADGRL3

7.95e-0434232IPR017983
DomainGPS

ADGRL2 ADGRL3

8.42e-0435232PF01825
DomainGPS

ADGRL2 ADGRL3

8.91e-0436232PS50221
DomainGPS

ADGRL2 ADGRL3

9.41e-0437232IPR000203
DomainG_PROTEIN_RECEP_F2_1

ADGRL2 ADGRL3

1.10e-0340232PS00649
DomainG_PROTEIN_RECEP_F2_3

ADGRL2 ADGRL3

1.10e-0340232PS50227
DomainGPCR_2_extracellular_dom

ADGRL2 ADGRL3

1.10e-0340232IPR001879
DomainG_PROTEIN_RECEP_F2_2

ADGRL2 ADGRL3

1.71e-0350232PS00650
Domain7tm_2

ADGRL2 ADGRL3

1.71e-0350232PF00002
PathwayWP_GPCRS_NONODORANT

FZD6 CASR ADGRL2 ADGRL3

2.43e-04266174MM15843
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

ADGRL2 ADGRL3

3.72e-0424172MM15992
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

ADGRL2 ADGRL3

3.72e-0424172M39643
Pubmed

Association of KIR2DL5B gene with celiac disease supports the susceptibility locus on 19q13.4.

KIR2DL5A KIR2DL5B

4.96e-07225217215859
Pubmed

Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B.

KIR2DL5A KIR2DL5B

4.96e-07225212185535
Pubmed

Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 gene.

KIR2DL5A KIR2DL5B

4.96e-07225211086080
Pubmed

Latrophilin GPCR signaling mediates synapse formation.

ADGRL2 ADGRL3

4.96e-07225233646123
Pubmed

Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins.

ADGRL2 ADGRL3

4.96e-07225230792275
Pubmed

A family of heptahelical receptors with adhesion-like domains: a marriage between two super families.

ADGRL2 ADGRL3

1.49e-06325210994649
Pubmed

The multiple actions of black widow spider toxins and their selective use in neurosecretion studies.

ADGRL2 ADGRL3

1.49e-06325215066411
Pubmed

Promoter variants of KIR2DL5 add to diversity and may impact gene expression.

KIR2DL5A KIR2DL5B

1.49e-06325218461314
Pubmed

JMJD3 aids in reprogramming of bone marrow progenitor cells to hepatic phenotype through epigenetic activation of hepatic transcription factors.

EZH2 F8

1.49e-06325228328977
Pubmed

Cyclin G associated kinase interacts with interleukin 12 receptor beta2 and suppresses interleukin 12 induced IFN-gamma production.

IL12RB1 GAK

1.49e-06325217937931
Pubmed

alpha-Latrotoxin and its receptors: neurexins and CIRL/latrophilins.

ADGRL2 ADGRL3

1.49e-06325211520923
Pubmed

Killer-cell immunoglobulin-like receptors (KIR) in severe A (H1N1) 2009 influenza infections.

KIR2DL5A KIR2DL5B

2.97e-06425222652695
Pubmed

KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains.

KIR2DL5A KIR2DL5B

2.97e-06425210820258
Pubmed

Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum.

ADGRL2 ADGRL3

2.97e-06425232202499
Pubmed

Investigation of killer cell immunoglobulin-like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5.

KIR2DL5A KIR2DL5B

2.97e-06425218498296
Pubmed

The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins.

ADGRL2 ADGRL3

7.43e-06625210964907
Pubmed

Mid-region parathyroid hormone-related protein (PTHrP) and gene expression of MDA-MB231 breast cancer cells.

FZD6 EBAG9

1.39e-05825217516841
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

ADGRL2 ADGRL3

2.22e-051025238713721
Pubmed

Physical linkage of the A-raf-1, properdin, synapsin I, and TIMP genes on the human and mouse X chromosomes.

F8 ARAF

2.72e-05112521572636
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DL5A KIR2DL5B

3.85e-051325219120281
Pubmed

Essential functions of synapsins I and II in synaptic vesicle regulation.

F8 ARAF

3.85e-05132527777057
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR2DL5A KIR2DL5B

5.92e-051625216403292
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR2DL5A KIR2DL5B

6.70e-051725219218127
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR2DL5A KIR2DL5B

6.70e-051725220878400
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR2DL5A KIR2DL5B

6.70e-051725220650299
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR2DL5A KIR2DL5B

6.70e-051725219450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR2DL5A KIR2DL5B

6.70e-051725219761533
Pubmed

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.

KIR2DL5A KIR2DL5B

7.54e-051825220200544
Pubmed

HLA and KIR frequencies in Sicilian Centenarians.

KIR2DL5A KIR2DL5B

9.35e-052025220426625
Pubmed

Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.

KIR2DL5A KIR2DL5B

9.35e-052025220193031
Pubmed

Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).

KIR2DL5A KIR2DL5B

1.14e-042225220492596
Pubmed

In Vitro Identification of Histatin 5 Salivary Complexes.

MUC7 F8

1.72e-042725226544073
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRL2 ADGRL3

1.99e-042925215203201
Pubmed

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.

ADGRL2 ADGRL3

2.58e-043325225713288
Pubmed

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

KIR2DL5A KIR2DL5B

2.91e-043525219683555
Pubmed

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.

ADGRL2 ADGRL3

6.43e-045225224613359
CytobandEnsembl 112 genes in cytogenetic band chr4q13

MUC7 ADGRL3

3.31e-03157252chr4q13
Cytoband16p11.2

NPIPB8 NPIPB6

4.85e-0319125216p11.2
Cytoband19p13.3

KIR2DL5A KIR2DL5B

7.36e-0323725219p13.3
GeneFamilyAdhesion G protein-coupled receptors, subfamily L

ADGRL2 ADGRL3

4.40e-064162918
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DL5A KIR2DL5B

1.11e-0418162620
CoexpressionGSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP

SPIRE1 SLFN12L F8 TRIM62

2.60e-05200234M6524
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDE3B ADGRL2 F8 ADGRL3

3.02e-061982341d30a1f73b6d6d838f49751402a29c5ef54aa81f
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDE3B ADGRL2 F8 ADGRL3

3.08e-06199234d58edc5f74970bb26d844746184e4bae7c494d6b
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Polydendrocyte.Tnr.Ctps_(Ctps)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR TEX50

8.66e-06782332b0973122052bb26153f066e7b87c26f8a319698
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr|Entopeduncular / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR TEX50

8.66e-06782331ddbb2247450a8b1c159f524dee15bf688748955
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SVOP F8 TRIM62

6.13e-051502336785b695a01de47a47f5c94fdc432428ef80bada
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SVOP F8 TRIM62

6.13e-05150233ddfb7dd696f06e834c45d6c3f9b1138bc17d62b3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPIRE1 PDE3B ADGRL2

7.70e-05162233285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPIRE1 PDE3B ADGRL2

7.98e-051642336fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCell(6)_Endothelial_cells-(6)_Endothelial-E|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

PDE3B ADGRL2 ADGRL3

9.51e-051742334a1b67ce5ea353b3f81f59fa57da07668146afca
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE3B ADGRL2 ADGRL3

9.51e-05174233f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL12RB1 SLFN12L PDE3B

9.51e-0517423347e308a777c927ae69ed344cb3dd8561bf2c48a5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL12RB1 SLFN12L PDE3B

9.51e-05174233a92c745d20633909db0f08effa13fc738fda79a6
ToppCellControl|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.00e-04177233b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-MAIT_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL12RB1 SLFN12L PDE3B

1.02e-04178233f52f837e948deb6a2d031325f49891bca8d375da
ToppCelldroplet-Spleen-nan-21m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 LHFPL4 EZH2

1.03e-04179233dabecd283c1f0f71a66b804c99be8bd48ea36e35
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.05e-04180233544fb373a3346186ec60afe2cfcf141bb04a1eed
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

GAK ADGRL2 F8

1.05e-04180233493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPIRE1 PDE3B ADGRL2

1.05e-04180233788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD6 ADGRL2 F8

1.07e-04181233a53f05c4c47465ee62e353716456bd09ab464b23
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(other)|COVID-19 / group, cell type (main and fine annotations)

ADGRL2 F8 ADGRL3

1.07e-0418123326eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCellNS-moderate-d_0-4-Lymphoid-CTL|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IL12RB1 SLFN12L PDE3B

1.07e-041812337fb3c1d29c542a3cea7fa654432d501d82df138f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPIRE1 PDE3B ADGRL2

1.09e-04182233f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.10e-04183233e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL12RB1 SLFN12L PDE3B

1.12e-041842336ce9aea2c1c9098f37bdf5135b5e2192ef03b50b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL12RB1 SLFN12L PDE3B

1.12e-04184233895f7492d47c4782809bbb125c258127de04f888
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 EZH2 TRIM62

1.12e-04184233b998803180322a5ea2b567928dea531c26816c3c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL12RB1 SLFN12L PDE3B

1.12e-041842336119140287ab4b88e41194bf8d6f77ae264b3b98
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.18e-04187233ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDE3B ADGRL2 ADGRL3

1.18e-0418723397b2463fb37e7196dd2f92553acf8e7bc3ec40dd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SPIRE1 CASR ADGRL2

1.18e-0418723377886f99c229610abd28c4c370d2c7d1536c9782
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRL2 F8 ADGRL3

1.20e-04188233117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellCOVID-19-kidney-T-cells-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLFN12L PDE3B EZH2

1.20e-0418823315484c05cb496cd98ed3f79a6134c5cec8f09a4d
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.20e-0418823373f6ec915934154f435a376cb274b058ff7c5f35
ToppCellControl-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

PDE3B ADGRL2 ADGRL3

1.20e-0418823388b3415e33db81726dd29c1f50c886e057af50a0
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.23e-04190233474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

ADGRL2 F8 ADGRL3

1.23e-04190233812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellEndothelial-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CASR ADGRL2 F8

1.25e-04191233f702dfe88a9b04091dae87df61b2b4f43525f86a
ToppCellCOVID-19-kidney-T-cells-2|kidney / Disease (COVID-19 only), tissue and cell type

SLFN12L PDE3B EZH2

1.25e-04191233698e6a28276704f8baa082d028db2345b973c4bc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPIRE1 PDE3B ADGRL2

1.25e-0419123396b78b4e819ea6052334bfcbc7abbf35897df885
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.27e-04192233c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.27e-0419223304f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellNS-critical-d_07-13-Lymphoid-Treg|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IL12RB1 SLFN12L PDE3B

1.27e-04192233cd34defac6565d34db507918e791b09c79f7d1f8
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.27e-04192233c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.29e-04193233aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.29e-04193233af5108260783e69a7d67896c5bf64f862525926d
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.29e-04193233c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.29e-04193233a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.29e-041932335122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.29e-0419323302f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.29e-041932336e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRL2 F8 ADGRL3

1.31e-0419423371ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.31e-041942330b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.31e-04194233bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.31e-041942331d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.31e-0419423343f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B ADGRL2 ADGRL3

1.31e-0419423358f069efdefa0366033764446b9d6ffd4a17807e
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLFN12L PDE3B ADGRL2

1.31e-04194233b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRL2 F8 ADGRL3

1.33e-04195233094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLFN12L PDE3B ADGRL2

1.33e-041952330e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

SLFN12L PDE3B EZH2

1.33e-041952337e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCellTracheal-10x5prime-Immune_Lymphocytic-T-T_CD4-T_reg|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL12RB1 SLFN12L PDE3B

1.35e-04196233c0028307cf5dddfc4b5db1445fa83b74019a20bd
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3B ADGRL2 F8

1.35e-04196233ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCellproximal-Endothelial-Capillary-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PDE3B ADGRL2 ADGRL3

1.37e-04197233ddb8ea895f0f34d4f20a0740b708fa0f3e378801
ToppCellproximal-3-Endothelial-Capillary|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PDE3B ADGRL2 ADGRL3

1.37e-04197233a1a61c03d67272693ec23e0d15f0a12bf618e2da
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDE3B ADGRL2 F8

1.37e-0419723381718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCellproximal-Endothelial-Capillary|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PDE3B ADGRL2 ADGRL3

1.37e-0419723353baef54bd85c60ae24a3c163b3a3d937fb6ff0b
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGRL2 F8 ADGRL3

1.39e-04198233d5990cab01de6e6f3757f5a50ef70ced711bb1fa
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDE3B ADGRL2 ADGRL3

1.41e-04199233dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
ToppCellControl_saline|World / Treatment groups by lineage, cell group, cell type

FZD6 PDE3B ADGRL2

1.41e-0419923311c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PDE3B ADGRL2 ADGRL3

1.44e-042002335c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PDE3B ADGRL2 ADGRL3

1.44e-0420023372ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDE3B ADGRL2 ADGRL3

1.44e-04200233a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD3-NKT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IL12RB1 SLFN12L PDE3B

1.44e-04200233846d3f0e647040d0e372df0dfcd69a21d5da5aea
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD3|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IL12RB1 SLFN12L PDE3B

1.44e-04200233c70f06b243ae9804f97308ee02b4b5e1a4a6f9f3
ToppCellTracheal-10x5prime-Immune_Lymphocytic-NK-ILC|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL12RB1 SLFN12L PDE3B

1.44e-0420023344674ccfd1ad4ac45968484d70220bc0506e2651
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL12RB1 SLFN12L PDE3B

1.44e-042002339ef322486e46e4ff05a8cbe06cf8019e996c94b3
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDE3B ADGRL2 ADGRL3

1.44e-04200233105c67e4f5eff036013d655c8e8ac577d32dae2e
ToppCellTracheal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL12RB1 SLFN12L PDE3B

1.44e-0420023372e1cc0b222df3ab76164524676e91628e237995
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDE3B ADGRL2 ADGRL3

1.44e-0420023358a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDE3B ADGRL2 ADGRL3

1.44e-04200233d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDE3B ADGRL2 ADGRL3

1.44e-04200233b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellTracheal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL12RB1 SLFN12L PDE3B

1.44e-04200233b5d00efb4286ae63cb081ef774aa0b0ff90d6c8a
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

5.74e-04692323da27f504e82277fa4a8fb67d60fc26dee0a414f
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

5.91e-0470232ee86e3790ff1fd684b7dff8c9de70e75133e9046
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Polydendrocyte.Tnr.Ctps_(Ctps)|Thalamus / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

6.43e-04732320ea6106a85b31d037c9aa16e1ad6a9bcb5b2eda9
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr|Thalamus / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

6.43e-0473232f2361804ed2e052efc1236d8abfa39ab7cb68dd8
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL12RB1 CASR

6.43e-0473232582faedb369a099d0acf1565413e6b3ca2cfc564
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Tmem2_(Pdgfa)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

7.52e-0479232bcb9181d7de7a385b890523299f8290836aa536e
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Tmem2_(Pdgfa)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

7.52e-0479232cd182dbc8d0ccc2406e78c9ba71476c1f463359b
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

7.90e-04812329ac80b8393182676f061e0e71b8361f5ccba495c
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

7.90e-0481232fec374d1ae512f85e2f32620834c0ce2800faecb
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Oligodendrocyte.Tnf.Igsf8-Ctps_(Ctps)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

7.90e-04812324529c9b40330361d999a8532268e0ee935affd8d
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Polydendrocyte.Tnr.Opalin_(Opalin)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

8.10e-04822325cd8e47edb775eabf3e9a407c1c2d8a78afb9509
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

8.10e-04822321eeb259ec555879ee1962b7bc2c31c200fbb85cf
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Polydendrocyte.Tnr.Opalin_(Opalin)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

8.49e-0484232c798f5831711749273b2d47d645ab242839295a9
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

8.49e-048423238981522315205c356a7fa269a5e3c3331c9ee83
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

9.74e-049023278d902ca4490bd9cf6b3c8c239dd91c500c28f42
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-P1_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

9.74e-0490232d1caa6229848ff323d5f389ab9e5a018c362d6c8
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

9.74e-049023245a54b29d2696c50a3dc3a4b6dd00664c7052be8
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Ctps_(Ctps)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

IL12RB1 CASR

9.74e-04902324d75217fd6b376bfda3300962cbe4875b31ffdaf
Drug1y6r

EZH2 F8 ARAF

5.77e-0635233CID000446609
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

ADGRL2 ADGRL3

1.98e-0428222DOID:1094 (implicated_via_orthology)
Diseaseinvasive ductal carcinoma (is_marker_for)

EBAG9 EZH2

4.07e-0440222DOID:3008 (is_marker_for)
Diseaseautoimmune thyroid disease, systemic lupus erythematosus, type 1 diabetes mellitus, ankylosing spondylitis, psoriasis, common variable immunodeficiency, celiac disease, ulcerative colitis, Crohn's disease, autoimmune disease, juvenile idiopathic arthritis

ADGRL2 NPIPB6

1.24e-0370222EFO_0000384, EFO_0000676, EFO_0000729, EFO_0001060, EFO_0002609, EFO_0003898, EFO_0005140, EFO_0006812, MONDO_0005147, MONDO_0007915, MONDO_0015517
Diseasecardiomyopathy (implicated_via_orthology)

CASR ARAF

1.28e-0371222DOID:0050700 (implicated_via_orthology)
Diseasesoluble triggering receptor expressed on myeloid cells 2 measurement

SLFN12L SVOP ADGRL3

1.34e-03296223EFO_0010151

Protein segments in the cluster

PeptideGeneStartEntry
FSLLCCFSSSLFFIG

CASR

656

P41180
CLLAAICFFFAFKSR

CASR

781

P41180
LVCLLICIFTFCFFR

ADGRL3

876

Q9HAR2
CLAICIFTFCFFRGL

ADGRL2

861

O95490
FRLFKFCTCLATVFS

EBAG9

6

O00559
LFIILFFFLLHCCCS

KIR2DL5A

251

Q8N109
WSFLSSLFFCCTVFS

KCNK18

101

Q7Z418
LFIILFFFLLHCCCS

KIR2DL5B

251

Q8NHK3
FHTLFCRRCFKYDCF

EZH2

281

Q15910
ACAFFFLTCFLTRTK

PDE3B

126

Q13370
LRCYTFNILFCTSCL

NPIPB8

86

E9PQR5
FNILFCTSCLCVSFL

NPIPB8

91

E9PQR5
STCFFLCLLRFCFSA

F8

6

P00451
ILGCITCFSLFFFCN

LHFPL4

106

Q7Z7J7
LFVCICALSACFSFS

MUC7

6

Q8TAX7
SIFCLCATLFTFLTF

FZD6

206

O60353
AVAVCSFLCFCRLFS

GAK

516

O14976
SFLCFCRLFSTAEAA

GAK

521

O14976
FVRKTFFSLAFCDFC

ARAF

101

P10398
FCDFCLKFLFHGFRC

ARAF

111

P10398
FLRCCLSSGRCCYFA

IL12RB1

76

P42701
FNILFCTSCLCVSFL

NPIPB6

91

E9PJ23
CFVIFSFCSLLLFIC

SVOP

406

Q8N4V2
FDTSFCFASLFHLCC

TAAR9

111

Q96RI9
IFLFVCLFRFCLFVC

SLFN12L

566

Q6IEE8
CLFRFCLFVCWFVCF

SLFN12L

571

Q6IEE8
SSCLICFGFTLQSFC

TMEM94

1181

Q12767
GKLCFCCRTRRFSFF

SPIRE1

591

Q08AE8
SLLFICFFGESFCIC

TEX50

11

A0A1B0GTY4
LCFGSFLSCVCQTFS

nan

121

Q1RN00
LFCLTDRALLCFFCD

TRIM62

101

Q9BVG3