Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	keratin filament binding	VIM FAM83H	1.28e-04	6	59	2	GO:1990254
Domain	Rhs_assc_core	TENM4 TENM3	2.64e-05	3	56	2	IPR022385
Domain	Tox-GHH_dom	TENM4 TENM3	5.28e-05	4	56	2	IPR028916
Domain	Ten_N	TENM4 TENM3	5.28e-05	4	56	2	IPR009471
Domain	Ten_N	TENM4 TENM3	5.28e-05	4	56	2	PF06484
Domain	TENEURIN_N	TENM4 TENM3	5.28e-05	4	56	2	PS51361
Domain	Tox-GHH	TENM4 TENM3	5.28e-05	4	56	2	PF15636
Domain	YD	TENM4 TENM3	8.78e-05	5	56	2	IPR006530
Domain	BRK	CHD6 CHD7	1.31e-04	6	56	2	SM00592
Domain	BRK_domain	CHD6 CHD7	1.31e-04	6	56	2	IPR006576
Domain	BRK	CHD6 CHD7	1.31e-04	6	56	2	PF07533
Domain	DUF1669	FAM83H FAM83B	2.44e-04	8	56	2	IPR012461
Domain	DUF1669	FAM83H FAM83B	2.44e-04	8	56	2	PF07894
Domain	CAP_GLY	TBCB CLIP1	3.91e-04	10	56	2	PF01302
Domain	CAP_GLY_1	TBCB CLIP1	3.91e-04	10	56	2	PS00845
Domain	CAP_GLY_2	TBCB CLIP1	3.91e-04	10	56	2	PS50245
Domain	CAP-Gly_domain	TBCB CLIP1	3.91e-04	10	56	2	IPR000938
Domain	CAP_GLY	TBCB CLIP1	3.91e-04	10	56	2	SM01052
Domain	-	TBCB CLIP1	3.91e-04	10	56	2	2.30.30.190
Domain	NHL	TENM4 TENM3	6.74e-04	13	56	2	PS51125
Domain	CarboxyPept-like_regulatory	TENM4 TENM3	1.17e-03	17	56	2	IPR008969
Domain	Chromo_domain	CHD6 CHD7	2.34e-03	24	56	2	IPR023780
Domain	Rho_GTPase_activation_prot	PLXNA3 ARHGAP23 DEPDC1	2.34e-03	88	56	3	IPR008936
Domain	Chromo	CHD6 CHD7	2.74e-03	26	56	2	PF00385
Domain	CHROMO_1	CHD6 CHD7	3.17e-03	28	56	2	PS00598
Domain	CHROMO_2	CHD6 CHD7	3.17e-03	28	56	2	PS50013
Domain	ArfGap	ARFGAP3 GIT2	3.40e-03	29	56	2	SM00105
Domain	ArfGap	ARFGAP3 GIT2	3.40e-03	29	56	2	PF01412
Domain	ARFGAP	ARFGAP3 GIT2	3.40e-03	29	56	2	PS50115
Domain	ArfGAP	ARFGAP3 GIT2	3.40e-03	29	56	2	IPR001164
Domain	SNF2_N	CHD6 CHD7	4.13e-03	32	56	2	IPR000330
Domain	Chromodomain-like	CHD6 CHD7	4.13e-03	32	56	2	IPR016197
Domain	SNF2_N	CHD6 CHD7	4.13e-03	32	56	2	PF00176
Domain	Chromo/shadow_dom	CHD6 CHD7	4.39e-03	33	56	2	IPR000953
Domain	CHROMO	CHD6 CHD7	4.39e-03	33	56	2	SM00298
Domain	DNA/RNA_helicase_DEAH_CS	CHD6 CHD7	4.93e-03	35	56	2	IPR002464
Domain	EGF_3	FAT1 TENM4 HMCN1 TENM3	5.38e-03	235	56	4	PS50026
Domain	EGF	FAT1 TENM4 HMCN1 TENM3	5.38e-03	235	56	4	SM00181
Domain	DEAH_ATP_HELICASE	CHD6 CHD7	5.79e-03	38	56	2	PS00690
Domain	-	TENM4 TENM3	6.09e-03	39	56	2	2.120.10.30
Domain	EGF-like_dom	FAT1 TENM4 HMCN1 TENM3	6.58e-03	249	56	4	IPR000742
Domain	EGF_1	FAT1 TENM4 HMCN1 TENM3	7.15e-03	255	56	4	PS00022
Domain	EGF-like_CS	FAT1 TENM4 HMCN1 TENM3	7.75e-03	261	56	4	IPR013032
Domain	EGF_2	FAT1 TENM4 HMCN1 TENM3	8.17e-03	265	56	4	PS01186
Domain	6-blade_b-propeller_TolB-like	TENM4 TENM3	8.40e-03	46	56	2	IPR011042
Domain	PH_dom-like	ARHGAP23 ELMO2 FRMPD2 PLCB3 ARHGEF15	8.87e-03	426	56	5	IPR011993
Domain	SANT	CHD6 CHD7	9.86e-03	50	56	2	SM00717
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	FMNL3 VIM ARHGAP23 ELMO2 ARFGAP3 PPP1R12A GIT2 LAMTOR1 CLIP1 ARHGEF15 FAM83B	9.32e-07	649	39	11	MM15690
Pathway	REACTOME_RHO_GTPASE_CYCLE	FMNL3 VIM ARHGAP23 ELMO2 ARFGAP3 GIT2 LAMTOR1 ARHGEF15 FAM83B	2.34e-06	439	39	9	MM15595
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	FMNL3 VIM ARHGAP23 ELMO2 ARFGAP3 PPP1R12A GIT2 LAMTOR1 CLIP1 ARHGEF15 FAM83B	2.58e-06	720	39	11	M41838
Pathway	REACTOME_RHO_GTPASE_CYCLE	FMNL3 VIM ARHGAP23 ELMO2 ARFGAP3 GIT2 LAMTOR1 ARHGEF15 FAM83B	2.87e-06	450	39	9	M27078
Pathway	REACTOME_CDC42_GTPASE_CYCLE	FMNL3 ARFGAP3 GIT2 LAMTOR1 ARHGEF15	6.41e-05	155	39	5	M41808
Pathway	PID_ILK_PATHWAY	ELMO2 PPP1R12A GIT2	2.56e-04	45	39	3	M71
Pathway	REACTOME_RHOJ_GTPASE_CYCLE	FMNL3 GIT2 LAMTOR1	4.65e-04	55	39	3	M41815
Pubmed	Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands.	TENM4 TENM3	2.83e-06	2	59	2	35484136
Pubmed	The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.	CHD6 CHD7	8.48e-06	3	59	2	28533432
Pubmed	Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.	TENM4 TENM3	1.69e-05	4	59	2	10225957
Pubmed	Gigaxonin controls vimentin organization through a tubulin chaperone-independent pathway.	TBCB VIM	1.69e-05	4	59	2	19168853
Pubmed	All four members of the Ten-m/Odz family of transmembrane proteins form dimers.	TENM4 TENM3	1.69e-05	4	59	2	12000766
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	TBCB PLXNA3 VIM KRT7 RUNDC3A PCDHGB7 SETD5 PPP1R12A CHD6 ABCC2 PNISR	2.68e-05	1442	59	11	35575683
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ZNF48 SETD5 ARFGAP3 PPP1R12A ZFHX3 CHD6 CHD7 LAMTOR1 PNISR CCDC86 FAM83B	3.78e-05	1497	59	11	31527615
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TENM4 CHD6 CHD7 GIT2 ARHGEF15	4.08e-05	225	59	5	12168954
Pubmed	FGF2-dependent mesenchyme and laminin-111 are niche factors in salivary gland organoids.	VIM KRT7	5.91e-05	7	59	2	29361536
Pubmed	The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.	TENM4 TENM3	5.91e-05	7	59	2	10625539
Pubmed	Evidence for mesenchymal-epithelial transition associated with mouse hepatic stem cell differentiation.	VIM KRT7	5.91e-05	7	59	2	21347296
Pubmed	Identification of novel cadherins expressed in human melanoma cells.	FAT1 PCDHGB7	5.91e-05	7	59	2	9182820
Pubmed	The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.	TENM4 TENM3	5.91e-05	7	59	2	12915301
Pubmed	Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.	TENM4 TENM3	7.87e-05	8	59	2	10331952
Pubmed	Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae.	FMNL3 RUNDC3A ARHGAP23	8.08e-05	49	59	3	31609468
Pubmed	FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands.	FMNL3 ZFHX3	1.26e-04	10	59	2	9171351
Pubmed	Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.	TENM4 TENM3	1.26e-04	10	59	2	38713721
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	ZNF22 ARHGAP23 ELMO2 PPP1R12A NKTR GIT2 CCDC86 ARHGEF15	1.52e-04	916	59	8	32203420
Pubmed	The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms.	FAM83H FAM83B	1.54e-04	11	59	2	29789297
Pubmed	Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.	ARHGAP23 AJM1 PPP1R12A	2.06e-04	67	59	3	29254152
Pubmed	Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development.	VIM CHD7	2.18e-04	13	59	2	23319608
Pubmed	Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.	TBCB VIM ELMO2 GIT2 LAMTOR1	2.35e-04	327	59	5	15592455
Pubmed	Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch.	TENM3 ZFHX3	2.93e-04	15	59	2	31812516
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	VIM FAT1 TENM3 ARFGAP3 ZFHX3 LAMTOR1 FAM83B	3.36e-04	777	59	7	35844135
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	TGM1 FAT1 PLCB3 LAMTOR1 ABCC2 FAM83B	4.04e-04	569	59	6	30639242
Pubmed	Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities.	TENM4 IQUB	4.25e-04	18	59	2	20602751
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	TBCB VIM TGM1 ARHGAP23 CHD7 WDR13 CCDC86 FAM83H XPOT	4.33e-04	1353	59	9	29467282
Pubmed	Chronic otitis media is initiated by a bulla cavitation defect in the FBXO11 mouse model.	VIM KRT7	5.27e-04	20	59	2	30898767
Pubmed	Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.	PLXNA3 VIM	5.82e-04	21	59	2	21835343
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	VIM IKBKE ELMO2 PPP1R12A TESK2 FAM83H FAM83B	6.20e-04	861	59	7	36931259
Pubmed	Characterization and mapping of human genes encoding zinc finger proteins.	ZNF22 ZNF48	6.39e-04	22	59	2	1946370
Pubmed	The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity.	VIM KRT7	6.39e-04	22	59	2	11696558
Pubmed	Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.	ZNF22 ZNF48	6.39e-04	22	59	2	1505991
Pubmed	Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor.	VIM KRT7	7.00e-04	23	59	2	19841136
Pubmed	A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.	PLXNA3 VIM	7.62e-04	24	59	2	28893946
Pubmed	Screening the proteins that interact with calpain in a human heart cDNA library using a yeast two-hybrid system.	VIM LAMTOR1	8.28e-04	25	59	2	12358155
Pubmed	Identification of FBXO25-interacting proteins using an integrated proteomics approach.	VIM PPP1R12A XPOT	9.27e-04	112	59	3	20473970
Pubmed	Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate.	VIM KRT7	1.12e-03	29	59	2	18038450
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	PLXNA3 VIM DEPDC1 CHD6	1.27e-03	277	59	4	30745168
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	NKTR CCDC86 CLIP1 XPOT	1.41e-03	285	59	4	32838362
Pubmed	Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.	VIM FAT1 PPP1R12A GIT2	1.41e-03	285	59	4	21423176
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	VIM SETD5 ARFGAP3 PPP1R12A TESK2 NKTR GIT2 CLIP1	1.68e-03	1321	59	8	27173435
Interaction	RUNDC3A interactions	VIM USP2 RUNDC3A SYT17 CLIP1	9.38e-07	63	57	5	int:RUNDC3A
Interaction	BICD2 interactions	TBCB VIM USP2 ARFGAP3 CLIP1 ARHGEF15 FAM83B XPOT	2.49e-05	426	57	8	int:BICD2
Coexpression	GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_DN	RNF19A NAB2 CHD6 GIT2 CCDC86 CLIP1	5.73e-06	199	59	6	M3569
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TGM1 KRT7 CRYBG2 FAM83H FAM83B	5.44e-06	191	59	5	cd4e2e883c4955fb2d875e41bb6ebc680994dc8c
ToppCell	facs-Trachea-18m-Epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TGM1 KRT7 CRYBG2 FAM83H FAM83B	5.58e-06	192	59	5	c5823c5d4c58a4e9121a4b7d7256481d6d9e9b7f
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Airway-Club\|Control_saline / Treatment groups by lineage, cell group, cell type	USP2 KRT7 CRYBG2 SLC9A2 FAM83B	6.64e-06	199	59	5	5cc8b553a58669a30eb10845beb23983dcdf5a6a
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 VIM KRT7 FAT1 PNISR	6.64e-06	199	59	5	174f6013af6eafa577f84205a62927f2b367fda3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP2 NAB2 ZFHX3 PLCB3	4.45e-05	148	59	4	fd0d8386b94adb1bdc993fbb44d2d87852bfd7f0
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|367C / Donor, Lineage, Cell class and subclass (all cells)	FMNL3 PLXNA3 IKBKE RAD17	4.56e-05	149	59	4	41f28138bde45d0b814e116837e5a32b5e80d54a
ToppCell	367C-Lymphocytic-ILC-ILC-3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	USP2 HMCN1 NAB2 APOL4	6.17e-05	161	59	4	8de421c61f4d5a6e05fdb20e4d230e2db98ee4d5
ToppCell	facs-Brain_Myeloid-Hippocampus-24m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBG2 SPDYA ZFHX3 PNISR	7.11e-05	167	59	4	7f3224af9b30082b927a822b91f96e0c88151b4e
ToppCell	facs-Brain_Myeloid-Hippocampus-24m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBG2 SPDYA ZFHX3 PNISR	7.11e-05	167	59	4	a21a2b301d0a3d7a41e605f7a3c37548962a331d
ToppCell	facs-Brain_Myeloid-Hippocampus-24m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBG2 SPDYA ZFHX3 PNISR	7.11e-05	167	59	4	0e746483773bde6582874a33591ab2a578d724eb
ToppCell	facs-Brain_Myeloid-Hippocampus-24m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBG2 SPDYA ZFHX3 PNISR	7.61e-05	170	59	4	b4f2c05db2c2591561fd42febc72eed3b5e8f9fb
ToppCell	wk_20-22-Mesenchymal-Chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TENM4 TENM3 DCAF10 ZFHX3	7.79e-05	171	59	4	d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	CRYBG2 ARHGAP23 CLIP1 FAM83B	8.52e-05	175	59	4	0cc215109d9915af47e4d0a120ce2e46910715fa
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)\|343B / Donor, Lineage, Cell class and subclass (all cells)	HMCN1 IP6K3 TENM3 PCDHGB7	8.90e-05	177	59	4	e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	HMCN1 IP6K3 TENM3 PCDHGB7	8.90e-05	177	59	4	43ba6f12c2fb32698a420bf799d46ac1b558f146
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	HMCN1 RNF6 ELMO2 CHD6	9.10e-05	178	59	4	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FMNL3 VIM HMCN1 NAB2	9.10e-05	178	59	4	c30d3390fc4a7856f50ba8ff6694c0333165ddde
ToppCell	ASK454-Epithelial\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	KIAA0408 TGM1 KRT7 PCDHGB7	9.91e-05	182	59	4	ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 VIM HMCN1 ARHGEF15	9.91e-05	182	59	4	3b4dbf61ca0fe50efe05449815630e301cb76630
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 VIM HMCN1 ARHGEF15	9.91e-05	182	59	4	ab5761bf9af439231cd0f487b6467e372672a517
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT1 IKBKE CCDC86 FAM83H	1.01e-04	183	59	4	bbf27d2f4369031fadacacd6c432c06b1ec5abdb
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Basal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT7 FAT1 FAM83H FAM83B	1.01e-04	183	59	4	ecac1cfaff7553a60305b34d6cede6973ffb5430
ToppCell	facs-Lung-EPCAM-3m-Epithelial-respiratory_basal_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT7 FAT1 FAM83H FAM83B	1.01e-04	183	59	4	f6ebfd7f61e912f92bd07313cc213a171747ac03
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0408 FAT1 TENM4 HMCN1	1.03e-04	184	59	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN12 VIM PPP1R12A ZFHX3	1.03e-04	184	59	4	94748f63947db79a6b4540e3090a63689fdd9452
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN12 VIM PPP1R12A ZFHX3	1.03e-04	184	59	4	819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0408 FAT1 TENM4 HMCN1	1.03e-04	184	59	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0408 FAT1 TENM4 HMCN1	1.03e-04	184	59	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Mild_COVID-19-Epithelial-AT1/AT2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	KRT7 FAT1 SLC9A2 FAM83B	1.06e-04	185	59	4	c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FMNL3 PLXNA3 IKBKE RAD17	1.08e-04	186	59	4	74c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCell	facs-Trachea-nan-18m-Epithelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGM1 CRYBG2 FAM83H FAM83B	1.10e-04	187	59	4	8882a638af7165b2910ba8e932d55475d7bfb003
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	FMNL3 PLXNA3 IKBKE RAD17	1.10e-04	187	59	4	816d37a70f7ec382a268fe828b3dfe737a36a4bf
ToppCell	ASK454-Epithelial-Type_1\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	KIAA0408 TGM1 KRT7 PCDHGB7	1.12e-04	188	59	4	13f8ce8f24ac7d7ed87f4ae3b8f4096de29383c2
ToppCell	COVID-19-Epithelial-Ionocytes\|COVID-19 / Condition, Lineage and Cell class	KRT7 FAT1 SLC9A2 FAM83B	1.12e-04	188	59	4	a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Basal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT7 FAT1 FAM83H FAM83B	1.15e-04	189	59	4	783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCell	facs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT7 FAT1 FAM83H FAM83B	1.15e-04	189	59	4	88b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	USP2 IP6K3 NKTR PNISR	1.15e-04	189	59	4	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT7 FAT1 FAM83H FAM83B	1.17e-04	190	59	4	47e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT7 FAT1 FAM83H FAM83B	1.17e-04	190	59	4	261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 ARFGAP3 SPDYA FAM83B	1.17e-04	190	59	4	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 ARFGAP3 SPDYA FAM83B	1.17e-04	190	59	4	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT7 FAT1 RUNDC3A FAM83H	1.19e-04	191	59	4	b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FAT1 TENM4 PCDHGB7 APOL4	1.24e-04	193	59	4	5e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell	facs-Tongue-nan-3m-Epithelial-keratinocyte\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGM1 CRYBG2 CLIP1 FAM83B	1.24e-04	193	59	4	33437fdb417d78463caee14a9f0e094da1733829
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	SETD5 CHD6 NKTR PNISR	1.24e-04	193	59	4	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	VIM TENM4 HMCN1 TENM3	1.27e-04	194	59	4	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KRT7 FAT1 SLC9A2 GIT2	1.29e-04	195	59	4	3d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KRT7 TENM4 IP6K3 SYT17	1.32e-04	196	59	4	b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCell	severe-dn_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FAT1 SLC9A2 IKBKE RNF19A	1.32e-04	196	59	4	14baf176bce5750ef50d6838b748caf68c151e05
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VIM FAT1 TENM3 ARHGAP23	1.32e-04	196	59	4	545d2e4469924d333e3f655f559c899fa1260196
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FAT1 TENM4 TENM3 PCDHGB7	1.34e-04	197	59	4	2ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	USP2 IP6K3 PPP1R12A ZFHX3	1.34e-04	197	59	4	d16bb765afdc02406ffd7ce6a75bae72b66db66c
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TGM1 FAT1 ARHGAP23 FAM83B	1.37e-04	198	59	4	fc00cb25cdc6c31b7f9d397bc9f9a8f4e9708003
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VIM FAT1 TENM3 ARHGAP23	1.40e-04	199	59	4	b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VIM FAT1 TENM3 ARHGAP23	1.40e-04	199	59	4	c972d3036151403f26fa9d6271520639c281ab84
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HMCN1 NKTR CHD7 ARHGEF15	1.42e-04	200	59	4	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KIAA0408 FAT1 PPP1R12A ZFHX3	1.42e-04	200	59	4	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FAT1 TENM4 TENM3 APOL4	1.42e-04	200	59	4	3c898e81444b001835c3f1bbc68183078701b135
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KIAA0408 FAT1 PPP1R12A ZFHX3	1.42e-04	200	59	4	67dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FAT1 TENM4 TENM3 APOL4	1.42e-04	200	59	4	3eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCell	LPS_only-Mesenchymal_myocytic\|LPS_only / Treatment groups by lineage, cell group, cell type	KIAA0408 FAT1 PPP1R12A ZFHX3	1.42e-04	200	59	4	8bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCell	LPS_IL1RA-Mesenchymal_myocytic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KIAA0408 FAT1 PPP1R12A ZFHX3	1.42e-04	200	59	4	77631c471cc5d453a749784f838cfa6408caf09b
Disease	CHARGE syndrome (implicated_via_orthology)	CHD6 CHD7	7.38e-05	7	56	2	DOID:0050834 (implicated_via_orthology)
Disease	esophagus squamous cell carcinoma (is_marker_for)	KRT7 FAT1 SETD5	3.81e-04	74	56	3	DOID:3748 (is_marker_for)
Disease	Child Behaviour Checklist assessment	TENM4 TENM3	5.31e-04	18	56	2	EFO_0005661
Disease	Squamous cell carcinoma of esophagus	FAT1 RNF6 ABCC2	7.92e-04	95	56	3	C0279626
Disease	age at assessment, lateral ventricle volume change measurement	TENM4 RNF19A	1.20e-03	27	56	2	EFO_0008007, EFO_0021502
Disease	word list delayed recall measurement, memory performance	TENM4 CHD6	1.80e-03	33	56	2	EFO_0004874, EFO_0006805
Disease	lung non-small cell carcinoma (is_implicated_in)	FAT1 ZFHX3 ABCC2	2.36e-03	139	56	3	DOID:3908 (is_implicated_in)
Disease	Secondary Biliary Cholangitis	KRT7 ABCC2	2.90e-03	42	56	2	C0238065
Disease	Biliary cirrhosis	KRT7 ABCC2	2.90e-03	42	56	2	C0023892
Disease	Biliary Cirrhosis, Primary, 1	KRT7 ABCC2	2.90e-03	42	56	2	C4551595
Disease	Primary biliary cirrhosis	KRT7 ABCC2	3.62e-03	47	56	2	C0008312
Disease	Alzheimer disease, dementia, family history of Alzheimer’s disease	FMNL3 ASB3	3.77e-03	48	56	2	EFO_0009268, MONDO_0001627, MONDO_0004975

Protein segments in the cluster

Peptide	Gene	Start	Entry
YETRARLERLSASSS	ARFGAP3	441	Q9NP61
SLTSVSRTRRALVEF	CCDC86	21	Q9H6F5
YTRSAELTASRLTAT	APOL4	196	Q9BPW4
RRYAALSLSETSLTE	AJM1	501	C9J069
VRTSLRLLTSSAYRL	GIT2	696	Q14161
VTSEASYLRSLRLLT	ARHGEF15	426	O94989
TSTLTTRLRRLITAY	CHD7	1906	Q9P2D1
TRSLLREYSTSIATR	RAD17	486	O75943
RVSYSLIASDLESRT	PCDHGB7	486	Q9Y5F8
TTQLRSRYELTVRAS	FAT1	1941	Q14517
LLKAYSIRTASASRR	KRT7	451	P08729
LSRQVARESTYLSSL	NAB2	346	Q15742
RTLEVARTSLLYLSS	IKBKE	456	Q14164
SELLRSHSTDRRVYS	FAM83B	921	Q5T0W9
FTRSLSRYESLLRTA	PLXNA3	1591	P51805
ILRARRTTSSSDLTT	DCAF10	341	Q5QP82
QSLLLRSSTRRNSYI	DEPDC1	511	Q5TB30
LRRTTHNYTISLRSE	KIAA0408	676	Q6ZU52
YVSTSRQLRRLDSVT	ABCC2	1141	Q92887
LRALLSVIRSQSSYR	IP6K3	306	Q96PC2
YRNSRTSLSRTRRTI	HMCN1	5401	Q96RW7
ISSIRDTRTGRYARL	PLCB3	66	Q01970
RSSLKSERLRSDSYI	ASB3	471	Q9Y575
TQTLTSRYRDSRLRV	CAPN12	661	Q6ZSI9
SLSYSEILRLRQSER	ELMO2	501	Q96JJ3
SSALTARLRRLVTVY	CHD6	1391	Q8TD26
SYLLRKRLRGTSSES	FRMPD2	206	Q68DX3
SLARSARQSVLRYST	FMNL3	191	Q8IVF7
SRSLEEYRVTRTVRT	CRYBG2	166	Q8N1P7
RQYSTRLAVLSSSLT	LAMTOR1	86	Q6IAA8
TEFSVSSTSRRIYRC	IQUB	611	Q8NA54
RLAQYSGRTTLTSRE	H2BK1	76	A0A2R8Y619
VQRSSRLRSSLIFST	FAM83H	676	Q6ZRV2
SRTGLLTETSSRYAR	CLIP1	331	P30622
YVLTLILRTSSNDRR	DPY19L2P2	121	Q6ZN68
YITTALRDTRTTRRF	RUNDC3A	141	Q59EK9
RYVRLGLSSSSSLSS	SPDYA	236	Q5MJ70
STYSLTRRISSLESR	SYT17	101	Q9BSW7
RSSCVRKYSESRSSL	NKTR	791	P30414
SRLERSGIRTYVSTI	RNF6	446	Q9Y252
KSRISRYRTSSAQRL	SETD5	616	Q9C0A6
RAYSNSIVRSSRTTL	WDR13	76	Q9H1Z4
ELTRVLSSSSATERY	ATG4D	411	Q86TL0
RTFSLSSTLLRHRLT	ZNF48	366	Q96MX3
RLRTIRSSSISYSQE	RNF19A	276	Q9NV58
REHRASTSTSRYLSL	SLC9A2	656	Q9UBY0
AGRRSSYLLAITTER	ARHGAP23	606	Q9P227
TFRSEKRYSRSLTIA	TBCB	21	Q99426
VTTSTRTYSLGSALR	VIM	31	P08670
SLTRRRDAERRYTSS	TENM4	11	Q6N022
RRQTRLSEILYDSTR	TENM3	1951	Q9P273
SSAKVRSRTAYLFSR	XPOT	536	O43592
TIRFDSSFSRLRRSL	ZNF22	36	P17026
SRSRSYSRRIKIESN	PNISR	571	Q8TF01
LLLSRTYESSDRITL	TGM1	151	P22735
SSYRALISAFSRLTR	TESK2	41	Q96S53
LARDFSSLRTSDSYR	USP2	146	O75604
SKRSSRTRFTDYQLR	ZFHX3	2241	Q15911
VSSTTEVRERRRSYL	PPP1R12A	656	O14974