Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncysteine-type endopeptidase inhibitor activity

PTTG3P PTTG1 PTTG2

2.34e-0543263GO:0004869
GeneOntologyMolecularFunctionSH3 domain binding

SHANK1 PTTG3P PTTG1 PTTG2

3.34e-05143264GO:0017124
GeneOntologyMolecularFunctionheat shock protein binding

CYP1A1 PTTG3P PTTG1 PTTG2

5.56e-05163264GO:0031072
GeneOntologyMolecularFunctionribosome binding

PTTG3P PTTG1 PTTG2

4.97e-04120263GO:0043022
GeneOntologyMolecularFunctionendopeptidase inhibitor activity

PTTG3P PTTG1 PTTG2

1.61e-03180263GO:0004866
GeneOntologyMolecularFunctionpeptidase inhibitor activity

PTTG3P PTTG1 PTTG2

1.79e-03187263GO:0030414
GeneOntologyMolecularFunctionendopeptidase regulator activity

PTTG3P PTTG1 PTTG2

2.20e-03201263GO:0061135
GeneOntologyMolecularFunctionribonucleoprotein complex binding

PTTG3P PTTG1 PTTG2

2.36e-03206263GO:0043021
GeneOntologyMolecularFunctionpeptidase regulator activity

PTTG3P PTTG1 PTTG2

4.40e-03257263GO:0061134
GeneOntologyBiologicalProcessmitotic sister chromatid cohesion

PTTG3P PTTG1 PTTG2

1.23e-0536263GO:0007064
GeneOntologyBiologicalProcesssmoothened signaling pathway

PTTG3P PTTG1 PTTG2 ARL13B

6.61e-05176264GO:0007224
GeneOntologyBiologicalProcesssister chromatid cohesion

PTTG3P PTTG1 PTTG2

8.07e-0567263GO:0007062
GeneOntologyBiologicalProcesshomologous chromosome segregation

PTTG3P PTTG1 PTTG2

1.27e-0478263GO:0045143
GeneOntologyBiologicalProcesscell division

PIK3R4 PTTG3P PTTG1 SETD2 SGF29 PTTG2

1.88e-04697266GO:0051301
GeneOntologyBiologicalProcessprotein localization to organelle

PIK3R4 SETD2 GAK SGF29 CHAMP1 NACA ARL13B

3.08e-041091267GO:0033365
GeneOntologyCellularComponentaxoneme

PIK3R4 PTTG3P PTTG1 PTTG2 ARL13B

4.10e-06207255GO:0005930
GeneOntologyCellularComponentciliary plasm

PIK3R4 PTTG3P PTTG1 PTTG2 ARL13B

4.20e-06208255GO:0097014
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

PIK3R4 PTTG3P PTTG1 PTTG2 ARL13B

3.22e-05317255GO:0032838
GeneOntologyCellularComponentcytoplasmic region

PIK3R4 PTTG3P PTTG1 PTTG2 ARL13B

5.89e-05360255GO:0099568
GeneOntologyCellularComponentcilium

PIK3R4 PTTG3P PTTG1 CCDC34 PTTG2 ARL13B

5.42e-04898256GO:0005929
MousePhenodecreased pancreatic beta cell proliferation

PTTG3P PTTG1 PTTG2

4.78e-0711213MP:0011820
MousePhenoabnormal pancreatic beta cell proliferation

PTTG3P PTTG1 PTTG2

3.82e-0621213MP:0011818
MousePhenodecreased pancreatic beta cell mass

PTTG3P PTTG1 PTTG2

1.41e-0532213MP:0009114
MousePhenothymus hyperplasia

PTTG3P PTTG1 PTTG2

1.70e-0534213MP:0000708
MousePhenodecreased spleen weight

CYP1A1 PTTG3P PTTG1 PTTG2

2.18e-05113214MP:0004953
MousePhenoabnormal pancreatic beta cell mass

PTTG3P PTTG1 PTTG2

4.54e-0547213MP:0009112
MousePhenoabnormal cell cycle checkpoint function

PTTG3P PTTG1 PTTG2

1.26e-0466213MP:0004045
MousePhenoincreased grip strength

SHANK1 PTTG3P PTTG1 SETD2 PTTG2

2.24e-04387215MP:0010052
MousePhenopolyuria

PTTG3P PTTG1 PTTG2

3.05e-0489213MP:0001762
MousePhenosmall spleen

CYP1A1 PTTG3P PTTG1 CHAMP1 PTTG2

3.13e-04416215MP:0000692
MousePhenoincreased bleeding time

PTTG3P PTTG1 PTTG2

3.26e-0491213MP:0005606
MousePhenohyperglycemia

PTTG3P PTTG1 PTTG2

4.96e-04105213MP:0001559
MousePhenoabnormal pancreatic beta cell morphology

PTTG3P PTTG1 PTTG2

6.47e-04115213MP:0005217
MousePhenodecreased IgM level

PTTG3P PTTG1 PTTG2

6.47e-04115213MP:0001806
MousePhenodecreased exploration in new environment

SHANK1 SETD2 ZC2HC1A CHAMP1 CARMIL3

7.94e-04510215MP:0001417
MousePhenoenlarged thymus

PTTG3P PTTG1 GAK PTTG2

8.43e-04292214MP:0000709
MousePhenoabnormal epididymal fat pad morphology

PTTG3P PTTG1 PTTG2

8.45e-04126213MP:0006319
MousePhenoreduced female fertility

PATL2 PTTG3P PTTG1 PTTG2

8.87e-04296214MP:0001923
MousePhenoreduced fertility

SHANK1 GARIN5B PATL2 PTTG3P PTTG1 PTTG2

1.18e-03844216MP:0001921
MousePhenoabnormal thymus size

CYP1A1 PTTG3P PTTG1 GAK PTTG2

1.25e-03564215MP:0002364
MousePhenoabnormal urination

PTTG3P PTTG1 PTTG2

1.34e-03148213MP:0001756
MousePhenoabnormal spleen size

CYP1A1 PTTG3P PTTG1 SMPD1 GAK CHAMP1 PTTG2

1.36e-031203217MP:0002224
MousePhenoabnormal spleen weight

CYP1A1 PTTG3P PTTG1 PTTG2

1.85e-03361214MP:0004951
MousePhenoabnormal grip strength

SHANK1 TNRC6B PTTG3P PTTG1 SETD2 PTTG2

2.12e-03946216MP:0001515
MousePhenodecreased litter size

PATL2 PTTG3P PTTG1 PTTG2

2.23e-03380214MP:0001935
MousePhenoabnormal exploration in a new environment

SHANK1 SETD2 ZC2HC1A CHAMP1 CARMIL3

2.29e-03647215MP:0013189
MousePhenoabnormal litter size

PATL2 PTTG3P PTTG1 PTTG2

2.66e-03399214MP:0001933
MousePhenoincreased food intake

PTTG3P PTTG1 PTTG2

2.70e-03189213MP:0011939
MousePhenoabnormal pancreatic islet morphology

PTTG3P PTTG1 PTTG2

2.74e-03190213MP:0005215
MousePhenoabnormal endocrine pancreas morphology

PTTG3P PTTG1 PTTG2

2.79e-03191213MP:0009165
MousePhenoabnormal response to new environment

SHANK1 SETD2 ZC2HC1A CHAMP1 CARMIL3

2.98e-03687215MP:0001413
MousePhenoabnormal pancreatic beta cell physiology

PTTG3P PTTG1 PTTG2

3.00e-03196213MP:0003562
MousePhenoabnormal physical strength

SHANK1 TNRC6B PTTG3P PTTG1 SETD2 PTTG2

3.22e-031027216MP:0004262
MousePhenoabnormal endocrine pancreas physiology

PTTG3P PTTG1 PTTG2

3.26e-03202213MP:0010147
MousePhenoabnormal hippocampus pyramidal cell morphology

SHANK1 PIK3R4

3.26e-0357212MP:0009940
DomainSecurin

PTTG1 PTTG2

1.45e-062232PF04856
DomainSecurin_separation_inhibitor

PTTG1 PTTG2

1.45e-062232IPR006940
DomainSecurin_separation-inh_met

PTTG1 PTTG2

1.45e-062232IPR018008
DomainMetallo-depent_PP-like

SMPD1 CWF19L1

6.18e-0430232IPR029052
Domain-

SMPD1 CWF19L1

6.18e-04302323.60.21.10
PathwayREACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1

PTTG3P PTTG1 PTTG2

7.40e-0574163MM14678
PathwayREACTOME_ACTIVATION_OF_APC_C_AND_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS

PTTG3P PTTG1 PTTG2

8.34e-0577163MM14692
PathwayREACTOME_APC_C_MEDIATED_DEGRADATION_OF_CELL_CYCLE_PROTEINS

PTTG3P PTTG1 PTTG2

1.20e-0487163MM14677
PathwayKEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING

PTTG1 PTTG2

1.44e-0416162M47476
PathwayKEGG_MEDICUS_REFERENCE_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING

PTTG1 PTTG2

2.50e-0421162M47583
Pubmed

Identification of disease-relevant modulators of the SHH pathway in the developing brain.

PTTG3P PTTG1 PTTG2 ARL13B

3.08e-11926434463328
Pubmed

Mice lacking pituitary tumor transforming gene show testicular and splenic hypoplasia, thymic hyperplasia, thrombocytopenia, aberrant cell cycle progression, and premature centromere division.

PTTG3P PTTG1 PTTG2

3.71e-10326311682618
Pubmed

PTTG is a secretory protein in human pituitary adenomas and in mouse pituitary tumor cell lines.

PTTG3P PTTG1 PTTG2

3.71e-10326317652795
Pubmed

Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging.

PTTG3P PTTG1 PTTG2

3.71e-10326333173537
Pubmed

Pituitary tumor transforming gene (PTTG) transforming and transactivation activity.

PTTG3P PTTG1 PTTG2

3.71e-10326310713046
Pubmed

Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes.

PTTG3P PTTG1 PTTG2

3.71e-10326312626748
Pubmed

Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II.

PTTG3P PTTG1 PTTG2

3.71e-10326328516917
Pubmed

PTTG1 Reprograms Asparagine Metabolism to Promote Hepatocellular Carcinoma Progression.

PTTG3P PTTG1 PTTG2

3.71e-10326337159932
Pubmed

Sex-steroid milieu determines diabetes rescue in pttg-null mice.

PTTG3P PTTG1 PTTG2

3.71e-10326316731783
Pubmed

Pttg1/securin is required for the branching morphogenesis of the mammary gland and suppresses mammary tumorigenesis.

PTTG3P PTTG1 PTTG2

3.71e-10326324395789
Pubmed

Mechanisms for growth factor-induced pituitary tumor transforming gene-1 expression in pituitary folliculostellate TtT/GF cells.

PTTG3P PTTG1 PTTG2

3.71e-10326316959877
Pubmed

Characterization of the murine pituitary tumor transforming gene (PTTG) and its promoter.

PTTG3P PTTG1 PTTG2

3.71e-10326310650958
Pubmed

Regulation of pituitary tumor transforming gene (PTTG) expression and phosphorylation in thyroid cells.

PTTG3P PTTG1 PTTG2

3.71e-10326323867215
Pubmed

The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function.

PTTG3P PTTG1 PTTG2

3.71e-10326331073078
Pubmed

A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes.

PTTG3P PTTG1 PTTG2

3.71e-10326334262048
Pubmed

Characterization of the pituitary tumor transforming gene 1 knockout mouse retina.

PTTG3P PTTG1 PTTG2

3.71e-10326321203837
Pubmed

Pituitary tumor transforming gene as a novel regulatory factor of liver fibrosis.

PTTG3P PTTG1 PTTG2

3.71e-10326325936962
Pubmed

Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes.

PTTG3P PTTG1 PTTG2

3.71e-10326316322543
Pubmed

PTTG1 alleviates acute alcoholic liver injury by inhibiting endoplasmic reticulum stress-induced hepatocyte pyroptosis.

PTTG3P PTTG1 PTTG2

3.71e-10326336737842
Pubmed

Murine pituitary tumor-transforming gene functions as a securin protein in insulin-secreting cells.

PTTG3P PTTG1 PTTG2

3.71e-10326317065388
Pubmed

Discordant proliferation and differentiation in pituitary tumor-transforming gene-null bone marrow stem cells.

PTTG3P PTTG1 PTTG2

3.71e-10326317626243
Pubmed

Pituitary tumor transforming gene: an update.

PTTG3P PTTG1 PTTG2

3.71e-10326315281346
Pubmed

Pituitary senescence: the evolving role of Pttg.

PTTG3P PTTG1 PTTG2

3.71e-10326320153804
Pubmed

Securin and not CDK1/cyclin B1 regulates sister chromatid disjunction during meiosis II in mouse eggs.

PTTG3P PTTG1 PTTG2

3.71e-10326318639540
Pubmed

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

PTTG3P PTTG1 PTTG2

1.48e-09426315919720
Pubmed

Anaphase B precedes anaphase A in the mouse egg.

PTTG3P PTTG1 PTTG2

1.48e-09426322342753
Pubmed

Securin and separase phosphorylation act redundantly to maintain sister chromatid cohesion in mammalian cells.

PTTG3P PTTG1 PTTG2

1.48e-09426316030258
Pubmed

Tumorigenic potential of pituitary tumor transforming gene (PTTG) in vivo investigated using a transgenic mouse model, and effects of cross breeding with p53 (+/-) transgenic mice.

PTTG3P PTTG1 PTTG2

1.48e-09426323164239
Pubmed

Abnormal megakaryocyte development and platelet function in Nbeal2(-/-) mice.

PTTG3P PTTG1 PTTG2

1.48e-09426323861251
Pubmed

Degradation of securin in mouse and pig oocytes is dependent on ubiquitin-proteasome pathway and is required for proteolysis of the cohesion subunit, Rec8, at the metaphase-to-anaphase transition.

PTTG3P PTTG1 PTTG2

1.48e-09426316720305
Pubmed

The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer.

PTTG3P PTTG1 PTTG2

1.48e-09426317127711
Pubmed

Spatial learning and long-term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice.

PTTG3P PTTG1 PTTG2

1.48e-09426330259712
Pubmed

Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene.

PTTG3P PTTG1 PTTG2

1.48e-09426320116377
Pubmed

Expression of PTTG and prc1 genes during telencephalic neurogenesis.

PTTG3P PTTG1 PTTG2

1.48e-09426310727870
Pubmed

Pituitary tumor-transforming gene 1 regulates the patterning of retinal mosaics.

PTTG3P PTTG1 PTTG2

1.48e-09426324927528
Pubmed

The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase.

PTTG3P PTTG1 PTTG2

1.48e-09426316533944
Pubmed

Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression.

PTTG3P PTTG1 PTTG2

1.48e-09426316533945
Pubmed

Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression.

PTTG3P PTTG1 PTTG2

1.48e-09426317039256
Pubmed

Pituitary tumor transforming gene 1 induces tumor necrosis factor-α production from keratinocytes: implication for involvement in the pathophysiology of psoriasis.

PTTG3P PTTG1 PTTG2

1.48e-09426323677169
Pubmed

Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells.

PTTG3P PTTG1 PTTG2

1.48e-09426325421944
Pubmed

Preimplantation mouse embryos depend on inhibitory phosphorylation of separase to prevent chromosome missegregation.

PTTG3P PTTG1 PTTG2

1.48e-09426319124608
Pubmed

A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.

PTTG3P PTTG1 PTTG2

1.48e-09426317234588
Pubmed

Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation.

PTTG3P PTTG1 PTTG2

1.48e-09426319477929
Pubmed

The pituitary tumour-transforming gene 1/delta-like homologue 1 pathway plays a key role in liver fibrogenesis.

PTTG3P PTTG1 PTTG2

1.48e-09426335050550
Pubmed

Homologue disjunction in mouse oocytes requires proteolysis of securin and cyclin B1.

PTTG3P PTTG1 PTTG2

1.48e-09426314593421
Pubmed

Securin regulates entry into M-phase by modulating the stability of cyclin B.

PTTG3P PTTG1 PTTG2

1.48e-09426318364698
Pubmed

Securin is not required for cellular viability, but is required for normal growth of mouse embryonic fibroblasts.

PTTG3P PTTG1 PTTG2

1.48e-09426311516952
Pubmed

Glypican-1 regulates anaphase promoting complex/cyclosome substrates and cell cycle progression in endothelial cells.

PTTG3P PTTG1 PTTG2

1.48e-09426318417614
Pubmed

Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth.

PTTG3P PTTG1 PTTG2

3.70e-09526317975001
Pubmed

p21(Cip1) restrains pituitary tumor growth.

PTTG3P PTTG1 PTTG2

3.70e-09526318981426
Pubmed

The meiosis I-to-meiosis II transition in mouse oocytes requires separase activity.

PTTG3P PTTG1 PTTG2

3.70e-09526314561405
Pubmed

MEIKIN expression and its C-terminal phosphorylation by PLK1 is closely related the metaphase-anaphase transition by affecting cyclin B1 and Securin stabilization in meiotic oocyte.

PTTG3P PTTG1 PTTG2

3.70e-09526339093409
Pubmed

Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase.

PTTG3P PTTG1 PTTG2

3.70e-09526321156286
Pubmed

PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8.

PTTG3P PTTG1 PTTG2

3.70e-09526322535767
Pubmed

Smurf1 targets Securin for ubiquitin-dependent degradation and regulates the metaphase-to-anaphase transition.

PTTG3P PTTG1 PTTG2

3.70e-09526328658604
Pubmed

The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.

PTTG3P PTTG1 PTTG2

3.70e-09526316355229
Pubmed

Altered expression of securin (Pttg1) and serpina3n in the auditory system of hearing-impaired Tff3-deficient mice.

PTTG3P PTTG1 PTTG2

3.70e-09526321076990
Pubmed

mTOR promotes pituitary tumor development through activation of PTTG1.

PTTG3P PTTG1 PTTG2

7.41e-09626327524416
Pubmed

Involvement of histone deacetylase 1/2 in adrenocorticotropic hormone synthesis and proliferation of corticotroph tumor AtT-20 cells.

PTTG3P PTTG1 PTTG2

7.41e-09626333181265
Pubmed

Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation.

PTTG3P PTTG1 PTTG2

7.41e-09626321991377
Pubmed

Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos.

PTTG3P PTTG1 PTTG2

1.30e-08726317325031
Pubmed

Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy.

PTTG3P PTTG1 PTTG2

4.43e-081026326731471
Pubmed

Separase phosphosite mutation leads to genome instability and primordial germ cell depletion during oogenesis.

PTTG3P PTTG1 PTTG2

6.09e-081126321494564
Pubmed

Specificity and Redundancy of Profilin 1 and 2 Function in Brain Development and Neuronal Structure.

PTTG3P PTTG1 PTTG2

1.06e-071326334571959
Pubmed

Diminished pancreatic beta-cell mass in securin-null mice is caused by beta-cell apoptosis and senescence.

PTTG3P PTTG1 PTTG2

1.06e-071326319213844
Pubmed

TIF1β association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesis.

PTTG3P PTTG1 PTTG2

1.68e-071526321163256
Pubmed

Inhibitory phosphorylation of separase is essential for genome stability and viability of murine embryonic germ cells.

PTTG3P PTTG1 PTTG2

2.06e-071626318232736
Pubmed

Murine candidate bleomycin induced pulmonary fibrosis susceptibility genes identified by gene expression and sequence analysis of linkage regions.

PTTG3P PTTG1 PTTG2

4.89e-072126315937080
Pubmed

Gene signatures and prognostic analyses of the Tob/BTG pituitary tumor-transforming gene (PTTG) family in clinical breast cancer patients.

PTTG3P PTTG1

5.37e-07226233173433
Pubmed

The lncRNA PTTG3P promotes the progression of CRPC via upregulating PTTG1.

PTTG3P PTTG1

5.37e-07226233743960
Pubmed

The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma.

PTTG3P PTTG1

5.37e-07226229803224
Pubmed

Identification of the human pituitary tumor transforming gene (hPTTG) family: molecular structure, expression, and chromosomal localization.

PTTG3P PTTG2

5.37e-07226210806349
Pubmed

Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development.

PTTG3P PTTG1 PTTG2

9.53e-072626337727504
Pubmed

Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye.

PTTG3P PTTG1 PTTG2

1.07e-062726323676271
Pubmed

Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development.

PTTG3P PTTG1 PTTG2

1.49e-063026316420439
Pubmed

Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma.

PTTG3P PTTG1 PTTG2

2.19e-063426334050187
Pubmed

Individual retinal progenitor cells display extensive heterogeneity of gene expression.

PTTG3P PTTG1 PTTG2

3.88e-064126318270576
Pubmed

Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.

PATL2 PTTG3P PTTG1 BAHD1 PTTG2

3.93e-0632626517015433
Pubmed

Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior.

PTTG3P PTTG1 PTTG2

1.00e-055626329184203
Pubmed

Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure.

PTTG3P PTTG1 PTTG2

1.11e-055826337973188
Pubmed

Emergence of young human genes after a burst of retroposition in primates.

PTTG3P NACA

1.01e-042026216201836
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PTTG3P PTTG1 SGF29 CHAMP1 PTTG2 NACA

1.72e-04115526620360068
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TNRC6B SETD2 GAK CHAMP1 NACA

5.68e-0493426533916271
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

TNRC6B SETD2 GAK CHAMP1

6.97e-0454926438280479
CoexpressionLIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_QTL

PTTG3P PTTG1 PTTG2

8.31e-0719263MM848
CoexpressionVIETOR_IFRD1_TARGETS

PTTG3P PTTG1 PTTG2

2.49e-0627263MM655
CoexpressionLIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_DN

PTTG3P PTTG1 PTTG2

5.55e-0635263MM542
CoexpressionCHESLER_BRAIN_HIGHEST_GENETIC_VARIANCE

PTTG3P PTTG1 PTTG2

9.69e-0642263MM617
CoexpressionHU_GENOTOXIC_DAMAGE_4HR

PTTG3P PTTG1 PTTG2

1.04e-0543263MM1204
CoexpressionLIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP

PTTG3P PTTG1 PTTG2

1.36e-0547263MM539
CoexpressionBURTON_ADIPOGENESIS_PEAK_AT_24HR

PTTG3P PTTG1 PTTG2

1.45e-0548263MM1181
CoexpressionGSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_DN

CARD6 PTTG1 ZC2HC1A ARL13B

1.98e-05164264M2972
CoexpressionISHIDA_E2F_TARGETS

PTTG3P PTTG1 PTTG2

2.20e-0555263MM1264
CoexpressionGSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_DN

CARD6 SGF29 CWF19L1 ARL13B

4.23e-05199264M9283
CoexpressionGUO_HEX_TARGETS_DN

PTTG3P PTTG1 PTTG2

4.54e-0570263MM629
CoexpressionMCBRYAN_PUBERTAL_TGFB1_TARGETS_DN

PTTG3P PTTG1 PTTG2

4.54e-0570263MM994
CoexpressionCHESLER_BRAIN_QTL_CIS

PTTG3P PTTG1 PTTG2

5.81e-0576263MM611
CoexpressionMCBRYAN_PUBERTAL_BREAST_6_7WK_DN

PTTG3P PTTG1 PTTG2

8.69e-0587263MM992
CoexpressionDURCHDEWALD_SKIN_CARCINOGENESIS_UP

PTTG3P PTTG1 PTTG2

1.79e-04111263MM705
CoexpressionZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR

PTTG3P PTTG1 PTTG2

2.66e-04127263M2608
CoexpressionTABULA_MURIS_SENIS_MARROW_MATURE_ALPHA_BETA_T_CELL_AGEING

CARD6 PTTG3P PTTG1 SGF29 PTTG2

2.99e-04612265MM3804
CoexpressionTABULA_MURIS_SENIS_LIMB_MUSCLE_SKELETAL_MUSCLE_SATELLITE_CELL_AGEING

PTTG3P PTTG1 PTTG2

3.26e-04136263MM3747
CoexpressionTABULA_MURIS_SENIS_LIMB_MUSCLE_ENDOTHELIAL_CELL_AGEING

PTTG3P PTTG1 PTTG2

3.93e-04145263MM3744
CoexpressionKAUFFMANN_DNA_REPLICATION_GENES

PTTG3P PTTG1 PTTG2

4.01e-04146263M9372
CoexpressionTABULA_MURIS_SENIS_DIAPHRAGM_MESENCHYMAL_STEM_CELL_AGEING

PTTG3P PTTG1 PTTG2 NACA

5.95e-04397264MM3695
CoexpressionWANG_TUMOR_INVASIVENESS_UP

PTTG3P PTTG1 PTTG2 NACA

6.24e-04402264MM1248
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2

PTTG3P PTTG1 PTTG2

7.25e-04179263MM534
CoexpressionGSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_UP

CHAMP1 FAM186A NACA

8.23e-04187263M3287
CoexpressionJNK_DN.V1_DN

CYP1A1 ZC2HC1A BCL9

8.62e-04190263M2745
CoexpressionGSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_UP

CARD6 PTTG1 RGS22

9.16e-04194263M6159
CoexpressionGSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_DN

PTTG1 PXDNL RGS22

9.43e-04196263M9979
CoexpressionGSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_DN

CARD6 TNRC6B ZC2HC1A

9.85e-04199263M6711
CoexpressionGSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_UP

CYP1A1 PTTG1 CCDC34

1.00e-03200263M5093
CoexpressionGSE21360_NAIVE_VS_TERTIARY_MEMORY_CD8_TCELL_DN

PTTG3P PTTG1 SMPD1

1.00e-03200263M7612
CoexpressionGSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_UP

PIK3R4 TNRC6B CCDC34

1.00e-03200263M7072
CoexpressionGSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_UP

CARD6 TNRC6B BCL9

1.00e-03200263M9258
CoexpressionGSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_DN

CARD6 GAK BCL9

1.00e-03200263M7900
CoexpressionGSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN

CARD6 GAK CHAMP1

1.00e-03200263M7915
CoexpressionGSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_UP

PIK3R4 TNRC6B BCL9

1.00e-03200263M6019
CoexpressionGSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_DN

PATL2 PTTG1 BAHD1

1.00e-03200263M6552
CoexpressionGSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_DN

TNRC6B PATL2 PTTG1

1.00e-03200263M6554
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTTG3P PTTG1 CCDC34 PTTG2

8.63e-07127264aca98d8c91f2aa0a777b6e9480c9ea70d38ff393
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTTG3P PTTG1 CCDC34 PTTG2

1.77e-06152264f748ee34167f79ecda116aa1914afab47403385a
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTTG3P PTTG1 PTTG2

6.68e-05136263c71a02ae8feabb1f51477a7728800b765ef19675
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTTG3P PTTG1 PTTG2

7.91e-0514426381a18478bc7284b903a4cad67b9049576a8c2b72
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTTG1 CARMIL3 CWF19L1

1.38e-041742632a96a4fd7d9ef05213b26103c689cf3a26968713
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTTG3P PTTG1 PTTG2

1.58e-04182263f549b986caebc5eb1b2d12f34fe33087e8324a31
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PTTG1 CARMIL3 CCDC34

1.66e-041852639d424a8608b339dd6129c58d87626678d4ec4af7
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHANK1 PTTG1 CCDC34

1.82e-0419126350854384fdaa0efa2e3227659d544ed09ac102f2
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTTG1 CCDC34 PTTG2

1.85e-04192263f518839ecd9377537a414e8798766f7d91eafeac
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTTG3P PTTG1 PTTG2

1.85e-04192263849ac3c115e6f913e68ca050c308bc4c32cf662b
ToppCellcontrol-Lymphocytic-Prol._cells|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PTTG3P PTTG1 CCDC34

1.91e-041942634c76508de3291c952386caffda2d559629ba5998
ToppCellcontrol-Lymphocytic-Prol._cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PTTG3P PTTG1 CCDC34

1.97e-04196263886f7c865b086d6ebb4a1746865c30af6bbed345
ToppCellwk_15-18-Mesenchymal-Fibroblast-Early_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PTTG1 CCDC34 NACA

2.03e-04198263ecf0a8f2e07f336e23b6f32a2c48d3c7eb66572b
ToppCell15-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

PTTG1 CCDC34 PTTG2

2.06e-041992635c8b847b794b3e88722f5b841f2539a27251106c
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PTTG1 CCDC34 PTTG2

2.06e-0419926388d130e2451e61afb710edf552e6b346b9fcfb2b
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-T/NK_proliferative|Int-URO / Disease, condition lineage and cell class

PTTG1 CCDC34 PTTG2

2.09e-0420026399acc1ea01288efdd5b166aa20d66735f2bbe543
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a7-Slc17a6.Fezf2-3110035E14Rik_(Layer_5,_Retrosplenial_cortex_(RSG)_and_Subiculum,_Tshz2+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CYP1A1 FAM186A

8.45e-047426283b762542508f9d6407e4b0087d70bea81a8fc7d
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)--|Striatum / BrainAtlas - Mouse McCarroll V32

CYP1A1 PATL2

9.15e-04772627bb18406d404c51ee938cc577c155dc51868ddb9
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)|Striatum / BrainAtlas - Mouse McCarroll V32

CYP1A1 PATL2

9.15e-0477262ac311740424ff75b478b3c19fa0fae93776eb54e
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)-|Striatum / BrainAtlas - Mouse McCarroll V32

CYP1A1 PATL2

9.15e-04772629f2dbf922acb905d636427a766a217c0db9671d2
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|356C / Donor, Lineage, Cell class and subclass (all cells)

PIK3R4 CARMIL3

2.23e-031212624ec70ad316942d9ade7bbdbf0e117e7c52b59d90
ToppCellCOVID-19-kidney-Mito-rich_Int|kidney / Disease (COVID-19 only), tissue and cell type

CYP1A1 RGS22

2.53e-0312926257b705106aec7bbfc587de1ccd4f2335fc44dd6f
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTTG1 RGS22

2.73e-031342624d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTTG1 ZC2HC1A

2.98e-031402629f105687f5749399fd76043fd85da58be30f2caf
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PTTG1 ZC2HC1A

2.98e-03140262a3be1fb7d2eb44bc123456d03250502938d46d9d
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PIK3R4 CARMIL3

3.14e-0314426257d2846ec26d4490ec11c171af447b17a729437e
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

CYP1A1 PTTG2

3.27e-03147262743767abdb3b5ecad870b617f515b037ce280818
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

PATL2 BAHD1

3.32e-0314826280470353e12599440f711b6e107730763376d04d
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic_-_developing-DN4_thymocyte|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SHANK1 PTTG1

3.36e-0314926289faa84af68d4727180f39718964bb3bc65d8fe6
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTTG1 CCDC34

3.36e-031492622624ad3926efc9f0f169daae263cef16861f132b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CARD6 CARMIL3

3.45e-03151262b545823113a3450c5f841f7de48bf0937593544f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CARD6 CARMIL3

3.45e-031512620cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FAM186A ARL13B

3.54e-03153262ee6f4770c6e35d59bdeec5b0ecb10119fa8c3ca5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FAM186A ARL13B

3.54e-0315326290cd6efda83c0b4b80eae2c90e7ff45dfd936dc2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FAM186A ARL13B

3.54e-03153262a35149a0c8b4ec9ad27cc4b3d34fba3b8714a6a2
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CARD6 CARMIL3

3.54e-03153262e7d20c88466ff81db613869cf7a6a4bb95fd6c2f
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PIK3R4 PATL2

3.54e-03153262764fb5e5fa028c137b8ea65dcd5e4ec9b22191e9
ToppCell(2)_NK/T-(23)_CD4+_T_cell-(230)_CD4+/CD25+_Reg_T_cell|(23)_CD4+_T_cell / immune cells in Peripheral Blood (logTPM normalization)

PTTG1 ZC2HC1A

3.58e-03154262059bdf6843f94f5028d4df6aa025865a9edb4521
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5|390C / Donor, Lineage, Cell class and subclass (all cells)

PATL2 BCL9

3.63e-03155262afdd0aba0f3788c2fb916ffb453c5dd7cde2304c
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BAHD1 CCDC34

3.68e-03156262abea3c183d32062b009a79a2bdf861021989c7ef
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SGF29 CARMIL3

3.68e-03156262fbe23876f0899853cea3c5c4f3044a9cea064d5b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZC2HC1A CCDC34

3.72e-0315726229622bac6b16bb39cec4319bf4c4f92d33345e8a
ToppCellLPS-antiTNF-Endothelial-Epi-like-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SMPD1 CCDC34

3.72e-03157262abfd05ed993b80822739f47a735f154092a23632
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|367C / Donor, Lineage, Cell class and subclass (all cells)

PATL2 CARMIL3

3.77e-03158262c08b5e12cc2975e52965e22ec987d0d45a9a68e9
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZC2HC1A RGS22

3.82e-03159262b05fda31b77536a1878f55d3199563b53f9420b2
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ZC2HC1A RGS22

3.82e-03159262ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCellIIF-Lymphocyte-T_NK-CD4_CTL|IIF / Disease, Lineage and Cell Type

PATL2 PXDNL

3.82e-0315926264e2b57e09bf25b2582f154375bb88cfd02a2521
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 CARD6

3.82e-03159262656aa20706bdba81bbcc3e68e6058215b92b8802
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Neutrophil|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1A1 PATL2

3.86e-031602627af3fbe555ff2eb1272381411617646e9e8c0440
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTTG1 ZC2HC1A

3.91e-03161262b24293fdae9637983fcf4f2d4659a3554e00a53f
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PTTG1 ZC2HC1A

3.91e-03161262eddcbe266d4a84a340fa8f2128d2b7e293968dca
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTTG1 NACA

4.00e-03163262fd35f1237c23367753ac2bc3e893f0e3c714129c
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHANK1 CYP1A1

4.00e-0316326200e791358a7eb6c3e95f87afe22153845012e4a1
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Seminoma-_NOS|TCGA-Testes / Sample_Type by Project: Shred V9

PXDNL BAHD1

4.00e-0316326267551fefe22bd5b8178fa248fed2a6c17b19fb0f
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Seminoma-_NOS-5|TCGA-Testes / Sample_Type by Project: Shred V9

PXDNL BAHD1

4.00e-0316326280bc3732afd8501938753120b8403098c7c5e928
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTTG1 CHAMP1

4.10e-0316526260b500eb2c10cccf309b8fb28a9119da22d6889c
ToppCellsevere_influenza-CD4+_CTL|World / disease group, cell group and cell class (v2)

PATL2 PTTG1

4.15e-03166262cdc3e200373718f26fe02ee516928097103f46e2
ToppCellDividing_Macrophages-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

PTTG1 CCDC34

4.15e-03166262ea95b94ccc2ac67df741b30c27f4ae698925875f
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

ZC2HC1A RGS22

4.20e-0316726226cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

CCDC34 PTTG2

4.20e-03167262315cde87eed2b42a1b9b068fae94caa10ec64c70
ToppCellfacs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZC2HC1A CHAMP1

4.20e-03167262961e722442d786ab15d1e490941d2be265a9057a
ToppCellfacs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZC2HC1A CHAMP1

4.20e-031672623760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCellmild_COVID-19-Treg|World / disease group, cell group and cell class (v2)

PTTG1 ZC2HC1A

4.20e-0316726269330689b6e353c8ee9ea1b63a5eac6ab38d456f
ToppCellCOVID-19_Moderate-Treg|COVID-19_Moderate / disease group, cell group and cell class

PTTG1 ZC2HC1A

4.20e-031672624ddb21421cbe72c06b61dd3a5eb1337e59de42e5
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP1A1 PTTG1

4.25e-03168262c7021748003e5949f7caf7b3291c5bad294948c1
ToppCellsevere_influenza-CD4+_CTL|severe_influenza / disease group, cell group and cell class (v2)

PATL2 PTTG1

4.25e-0316826250697fda702a09d9a621e9f79c2b52d53792dd2a
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZC2HC1A RGS22

4.25e-031682629a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tnaive/CM_CD8|GI_small-bowel / Manually curated celltypes from each tissue

CCDC34 PTTG2

4.25e-03168262c51244b4bdbfd961e2725306aa9cb25dd66d58bd
ToppCellDividing_Macrophages-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

PTTG1 CCDC34

4.30e-03169262eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCellDividing_Macrophages-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

PTTG1 CCDC34

4.30e-03169262bc859a103cad567caf50c3c3882d2d2017807c73
ToppCellsevere_influenza-gd_T|World / disease group, cell group and cell class (v2)

CYP1A1 PATL2

4.30e-031692626d514dd2d1e5253bce49279f43aa2fa2b7c2653e
ToppCellMild-Treg|World / Disease group and Cell class

PTTG1 ZC2HC1A

4.35e-03170262f3f177534badca34e1ae8671b7f583ee6688e14b
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 CARMIL3

4.40e-0317126243d8fd9b9546e84a652564fe96b514b34b06262b
ToppCellT_cells-GNLY+GZMB+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PATL2 CARMIL3

4.40e-0317126204c811817cfec45af5f2891793106cc7ddb0300e
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CCDC34 PTTG2

4.40e-031712624ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCellNS-critical-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTTG1 SGF29

4.40e-03171262bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 CARMIL3

4.40e-03171262a31c23406cf6d6a17358a8fb41d392a7fb0306e0
ToppCellmild_COVID-19-Treg|mild_COVID-19 / disease group, cell group and cell class (v2)

PTTG1 ZC2HC1A

4.45e-0317226277af6324c06b67867e7ce07706536fe38de5ed7b
ToppCellIIH-CD8-CD8_2|IIH / Condition, Cell_class and T cell subcluster

PATL2 PXDNL

4.45e-031722621466cb4298c63e995b3368d296b254e0e76a1b41
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PTTG1 CCDC34

4.45e-031722627f3d0ef18f5df1ed80498d435b0378ca398c0b88
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GARIN5B PTTG1

4.45e-03172262e9095c3dac66cf93d31f5f88364b565abacb1e2d
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CARD6 SETD2

4.50e-03173262b6bb2a136a40f0946bbcde8d5972d3f059d080c7
ToppCellcontrol-Lymphocytic-CD4_T_cells_3|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PTTG1 ZC2HC1A

4.50e-031732620c9fb18536ddd61b51b7bb4d40841f67b017f360
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTTG1 CCDC34

4.55e-03174262b6725086fe5a2b057c7c495ec63c970ac52c2580
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTTG1 CCDC34

4.55e-03174262e70cc623a3a6aceec813ed852fec0c4240561133
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SETD2 BAHD1

4.55e-03174262271c51d220842402975d97c86c9acfdbdf62a32c
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTTG1 CCDC34

4.55e-031742629bb8159a62640756d18ecbade3bf32bcbb7dd590
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTTG1 CCDC34

4.55e-0317426246cbb462173a684ceb9e680f9259dc3b133763f7
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PATL2 ARL13B

4.60e-0317526226bd957498e41a3f1ffa60d3effa27ca8c4ba631
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PATL2 SMPD1

4.60e-0317526241174b7381932a2cc94063c7202eeff6d3208cc7
ToppCell5'-Adult-LargeIntestine-Mesenchymal-stromal_related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZC2HC1A RGS22

4.60e-03175262b8995e7ada85ba959f06264a0295b61e390c4e6c
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PTTG1 CCDC34

4.60e-031752626b4e841bde6cfa4956e1a0231672cea20f11210c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZC2HC1A RGS22

4.60e-031752627ae76bd3b4f610b2f98716a4456437cd3696b686
ToppCell(2)_NK/T-(23)_CD4+_T_cell-(232)_CD4+/CD45RA+_Naive_T_cell|(23)_CD4+_T_cell / immune cells in Peripheral Blood (logTPM normalization)

SMPD1 NACA

4.60e-03175262fc40fda0fb9954cb0970c6ac71f6d6df7d27dc5c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTTG1 CCDC34

4.60e-0317526216c835e62a3321f6cf6163954889946bbb869498
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PTTG1 ZC2HC1A

4.65e-03176262856a8c4211ea33d926b18d8959a03909562aa563
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

PTTG1 CCDC34

4.65e-03176262a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TNRC6B PXDNL

4.70e-03177262b7fee75de7e96924af488a5baa2334711889ae7c
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZC2HC1A BCL9

4.70e-031772624672cc75225a4a23b298afa8ce439628262519db
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM186A CCDC34

4.70e-031772623081ce5fc66a1bb833719d6c0e0a6fc7115eeb91
DiseaseNeurodevelopmental Disorders

TNRC6B SETD2

2.59e-0393242C1535926
DiseasePsychotic Disorders

SHANK1 BCL9

3.05e-03101242C0033975
DiseasePapillary Renal Cell Carcinoma

SHANK1 SETD2

4.84e-03128242C1306837
DiseaseRenal Cell Carcinoma

SHANK1 SETD2

4.84e-03128242C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

SHANK1 SETD2

4.84e-03128242C1266043
DiseaseChromophobe Renal Cell Carcinoma

SHANK1 SETD2

4.84e-03128242C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

SHANK1 SETD2

4.84e-03128242C1266044
DiseaseIntellectual Disability

SETD2 CHAMP1 ARL13B

5.52e-03447243C3714756
DiseaseSclerocystic Ovaries

TNRC6B CARMIL3

6.08e-03144242C1136382
DiseasePolycystic Ovary Syndrome

TNRC6B CARMIL3

6.08e-03144242C0032460
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

SHANK1 SETD2

6.42e-03148242C0279702

Protein segments in the cluster

PeptideGeneStartEntry
WNISLPTVPKPPPKP

SMPD1

176

P17405
PPPPPVGWGTPKVTR

ARL13B

376

Q3SXY8
PQVPKGLKNPPGPWG

CYP1A1

31

P04798
SWKPPPPPQSTKPSF

CARMIL3

1201

Q8ND23
KQPRKPPQPPGPCWF

CWF19L1

316

Q69YN2
PSPPAKKPWSQQPDP

PATL2

171

C9JE40
KTGFPWPPSGKPLLP

PXDNL

921

A1KZ92
WPPQAKPPPKACTQP

GAK

1131

O14976
PCKSTQPKPSQPWPP

CARD6

986

Q9BX69
YNPIPWKPIHMPPPK

CCDC34

316

Q96HJ3
PAKPAPSVSPGPWKP

CHAMP1

336

Q96JM3
LPAPSPGWTSSPKPP

BCL9

926

O00512
STEPPAPKAPRPKWP

BAHD1

236

Q8TBE0
PPTLWPSPAPGKPQK

FAM186A

1931

A6NE01
LGPPSPVKMPSPPWE

PTTG1

161

O95997
SPWIVKKPPSLPPPA

RGS22

166

Q8NE09
LGPPSPLKMPSPPWK

PTTG3P

161

Q9NZH4
LGPPSPVKMPSPPWE

PTTG2

161

Q9NZH5
FQNWPKPPLPPLPTG

SHANK1

1941

Q9Y566
ESKPPPPGWRPKGLL

PIK3R4

971

Q99570
PLWIGKPGDKPPPLC

SGF29

131

Q96ES7
PSPPKPKTIVLPPNW

SETD2

2381

Q9BYW2
PLKPRPEPPKKPSNW

ZC2HC1A

66

Q96GY0
PPPGLTNPKPSSPWS

TNRC6B

1601

Q9UPQ9
PASSWKPPPGLAPPQ

GARIN5B

426

Q8N5Q1
PPWDPKGPPKVPFRS

GARIN5B

786

Q8N5Q1
WAPTPPAATPPSPKG

NACA

961

E9PAV3